Note: Descriptions are shown in the official language in which they were submitted.
o~
l A specimen test slide has a front panel and a
rear panel. The front panel has a plurality of openings.
Sheet means underlie each of these openings for the recep-
tion of a specimen. The portion of the sheet under each
opening carries a test reagent. A hinged cover overlies
the openings. The rear panel has tab means opposite the
said openings which are pivotable to e~pose the underside
of the sheet to permit the application of a developing
solution. The reagent at each location may be the same or
different. When the reagents are different, they can be
separa~ely printed on the sheet to underlie diferent
openings. A single sheet is disclosed underlying all of
the openings with the employment of a barrier to llmit the
migration between adjacent portions of the sheet. The use
of separate sheets under each opening is also disclosed.
~ Background of the Invention
; It is known to employ specimen slides having a
specimen receiving sheet between a front panel and a rear
panel with an opening in the front panel and an opening in
the rear panel and pivotaL covers to cover these openings.
TypicallyJ in the case of a test for occult blood in feces,
the specimen receiving sheet is paper impregnated with
guaiac and a developing solution such as a peroxide solution
is applied through the opening in the rear panel.
Fre~uently it is highly desirable to have two or
more specimens for a close side-by-side comparison in the
test involved. For example, it is desirable to test more
than one portion of a fecal sample when testing Eor occult
blood. At times it is desirable ~o test a specimen by more
~han one test, for example, testing a fecal sample by both
--2--
1 the guaiac test and the o-tolidine test which have different
sensitivities is valuable in the diagnosis for occult blood.
The invention provides for the achievement of these objec-
tives.
Brief Summary of the Invention
The invention provides for side-by-side comparison
testing with the same and differen~ t~es~ reagents by pro-
viding multiple openings in the ront and rear panlels with
provisions for covering these openings. Advantageously
barrier means are provided to prevent migration from one
test portion of the slide to another test portion. An
entire sheet lying under all openings may carry the test
reagent or the sheet may carry the same or different test
reagents onl~ in selected portions opposite the openings
with the application of the reagent made, for example, by
printing Separate sheets may be employed under the open
ings with the same or different test reagents being used on
the sheets and applied, for example, by printing.
Brief Description o the Drawin~s
Figure lis a plan view o a partially processed
blank for making a slide in accordance with the invention;
Figure 2 is a front elevational view of a slide
formed from the blank of Figure 1 with the front cover
open;
Figure 3 is a rear view of the slide of Figure 2
with the front cover closed;
Figure 4 is a view, partially broken away, of a
modified blank for forming a slide; and
Figure ~ is a view, partially broken away, of
another modified blank for forming a slide employirlg
~o~
1 separate sheets.
Detailed Description
A blank 2 formed, for example, from paper or
~ardboard has a front panel 4, a rear panel ~ and a cover 8.
The blank 2 is creased between panels 4 and 6 along the line
indicated at 10 to facilitate folding. A crease along the
line indicated at 12 between panel 6 and cover 8 facilitates
the hinging of cover 8. Cover 8 has a tab 14 which is
adapted to pass through circular slit 16 in panel 4 and
circular slit 18 in panel 6 to lock the cover in the closed
position.
Front panel 4 has a pair o~ ad~acent openings 22
and 24. A sheet of absorbent paper 26, for example J filter
paper overlies (as viewed in Figure 1) openings 22 and 24.
Sheet 26 is impregnated with a reagent such as guaiacO A
barrier 28 in the central portion of sheet 2~ prevents
migration of the specimen or a developing solution between :.
the two halves of sheet 26. Barrier 28 may be any material
impregnating paper 26 which will prevent migration, ~or
example, gLue, a wax or a syn~hetic resin such as an epoxy,
phenolic~ polyester or silicone resin commonly used in
paper~resin laminates. As illustrated, barrier 28 is
formed of glue which is also deposi~ed on the front panel
24 as indicated at 32 and on rear panel 6 as indicated at
34 in order to adhere sheet 26 to both panels 4 and 6.
Panels 4 and 6 are adhered together by an adhesive such as
glue indicated at 35.
: For the application of the developing solution,
for example, a peroxide solution~ the rear panel 6 is
provided with tabs 38 and 40 opposite openings 22 and 243
9'~
1 respectively. Perforations 42 are provid~d ~o permit
moving the tabs 38 and 40 away rom sheet 26 pi~oting
about crease lines 44 and 46, respectively.
To form the completed slide 50 shown in Figure 2,
blank 2 is folded along crease line 10 to bring panels 4
and 6 together and hold them together principally by the
glue at 35, Cover 8 is now hinged about crease 12 and
secured to panel 4 by a spot of glue 52.
To use the slide device, the patient sep~rates
cover 8 from panel 4 at the spot 52, opens the cover and
applies with an applicator a thin smear of a specimen from
one portion of his stool on paper 26 through opening 22.
He then applies from another portion of his stool a thin
smear on paper 26 through opening 24. He then closes the
cover locking tab 14 in openings 16 and 18 and returns the
slide to his physician. On receiving the slide, the
physician pulls tabs 38 and 40 free of rear panel 6 and open~
them outwardly. Through the opening thus made the physician
applies a peroxide solution on the guaiac impregnated paper
26 opposite each o the openings 22 and 24 and observes the
test results, i.e,, in the occult blood test the degree to
which the color blue is developed. This provides a good
side-by-side comparison of tes~ results from two different
portions of the patient 19 stool.
As shown in Figure 4, a blank 2 for making a
slide in accordance with the invention has secured there~o
in lieu of sheet 26 a sheet 62 of paper which has a central
glue barrier 64. ShPet 62 differs from sheet 26 in that
rather than being impregnated throughout with one reagent,
it has printed thereon opposite opening 22 one reagent 66
1 and it has printed thereon opposite opening 24 a second
different reagent 68. Reagent 66 may be, for example,
guaiac and reagent 68 may be, for example, o-tolidine. In
use the reagents 66 and 68 may be developed with a peroxide
or an organic peroxide solution.
As shown in Figures 5 a blank 2 for use in making
a slide in accordance with the invent:ion has a separate
sheet 72 opposite opening 22 and a separate sheet 74 opposite
opening 24. Sheet 22 may be impregnated with, for example,
guaiac and sheet 74 impregnated with, for example, o-tolidine.
Sheet 72 is impregnated with epoxy resin indicatecl at 76
which acts as a barrier and secures sheet 72 to both the
front and rear panels. Similarly, sheet 74 is impregnated
with epoxy resin 78 which secures sheet 74 to both the
front and rear panels.
The above embodiments are illustrative and are
not intended to be limiting.
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