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Patent Summary

(12) Patent: (11) CA 1225398
(21) Application Number: 471120
(54) English Title: PHENYLACETIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM
(54) French Title: DERIVES DE L'ACIDE PHENYLACETIQUE, COMPOSES PHARMACEUTIQUES LES CONTENANT ET PROCEDE DE PREPARATION

Abstracts

English Abstract


Abstract

New phenylacetic acid derivatives of general
formula
Image (I)

wherein
R1 represents an unbranched alkyleneimino
group optionally substituted by one or two alkyl
groups,
R2 represents a hydrogen or halogen atom
or a methyl or methoxy group,
R3 represents a hydrogen atom, an alkyl group
or a phenyl group optionally substituted by a halogen
atom or by a methyl or methoxy group,
R4 represents a hydrogen atom, an alkyl group
optionally substituted by a phenyl group, or an
allyl, acetyl or propionyl group and
W represents a methyl, hydroxymethyl, formyl
carboxy group or an alkoxycarbonyl group optionally
substituted by a phenyl group,
and their salts have interesting pharmacological
properties, particularly a hypoglycaemic effect.
Processes for preparing these compounds and compositions
containing them are described and exemplified



Patent Details

(52) Canadian Patent Classification (CPC):
  • 260/292
  • 260/325.2
  • 260/241.51
(51) International Patent Classification (IPC):
  • C07D 211/14 (2006.01)
  • C07D 295/135 (2006.01)
  • C07D 295/14 (2006.01)
  • C07D 307/14 (2006.01)
  • C07D 309/04 (2006.01)
(72) Inventors (Country):
  • GRELL, WOLFGANG (Germany)
  • HURNAUS, RUDOLF (Germany)
  • GRISS, GERHART, (DECEASED) (Germany)
  • SAUTER, ROBERT (Germany)
  • RUPPRECHT, ECKHARD (Germany)
(73) Owners (Country):
  • THOMAE (DR. KARL) GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (Afghanistan)
(71) Applicants (Country):
(74) Agent: FETHERSTONHAUGH & CO.
(45) Issued: 1987-08-11
(22) Filed Date: 1984-12-28
(30) Availability of licence: N/A
(30) Language of filing: English

(30) Application Priority Data:
Application No. Country Date
P 33 47 565.2 Germany 1983-12-30

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View Patent Image Download Patent Image in PDF Format Size of Image (KB) Number of Pages
Cover Page Cover Page 24 1
Abstract Abstract 27 1
Claims Claims 398 13
Description Description 2,236 65
Drawings Drawings 15 1
Representative Drawing Representative Drawing N/A N/A

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