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(12) Patent: | (11) CA 1315689 |
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(21) Application Number: | 548964 |
(54) English Title: | QUARTERNARY DERIVATIVES OF NOROXYMORPHONE WHICH RELIEVE NAUSEA AND EMESIS |
(54) French Title: | DERIVES QUATERNAIRES DE LA NOROXYMORPHONE SOULAGEANT LA NAUSEE ET LE VOMISSEMENT |
Status: | Expired |
(52) Canadian Patent Classification (CPC): |
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(51) International Patent Classification (IPC): |
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(72) Inventors : |
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(73) Owners : |
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(71) Applicants : | |
(74) Agent: | FETHERSTONHAUGH & CO. |
(74) Associate agent: | |
(45) Issued: | 1993-04-06 |
(22) Filed Date: | 1987-10-09 |
Availability of licence: | N/A |
(25) Language of filing: | English |
Patent Cooperation Treaty (PCT): | No |
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(30) Application Priority Data: | ||||||
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QUATERNARY DERIVATIVES OF NOROXYMORPHONE
WHICH RELIEVE NAUSEA AND EMESIS
ABSTRACT OF THE DISCLOSURE
Quaternary derivatives of noroxymorphone are used
to prevent or relieve nausea and emesis associated with
the use of narcotic analgesics without interfering with
the analgesic activity of the drugs. A particularly
preferred compound is methylnaltrexone. The compound is
administered in a concentration between 0.05 mg/kg and
1.0 mg/kg prior to or concurrently with the
administration of the narcotic analgesic.
Note: Claims are shown in the official language in which they were submitted.
Note: Descriptions are shown in the official language in which they were submitted.
Sorry, the representative drawing for patent document number 1315689 was not found.
For a clearer understanding of the status of the application/patent presented on this page, the site Disclaimer , as well as the definitions for Patent , Administrative Status , Maintenance Fee and Payment History should be consulted.
Title | Date |
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Forecasted Issue Date | 1993-04-06 |
(22) Filed | 1987-10-09 |
(45) Issued | 1993-04-06 |
Expired | 2010-04-06 |
There is no abandonment history.
Fee Type | Anniversary Year | Due Date | Amount Paid | Paid Date |
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Application Fee | $0.00 | 1987-10-09 | ||
Registration of a document - section 124 | $0.00 | 1987-12-21 | ||
Maintenance Fee - Patent - Old Act | 2 | 1995-04-06 | $100.00 | 1995-03-10 |
Maintenance Fee - Patent - Old Act | 3 | 1996-04-08 | $100.00 | 1996-03-19 |
Maintenance Fee - Patent - Old Act | 4 | 1997-04-07 | $100.00 | 1997-03-19 |
Maintenance Fee - Patent - Old Act | 5 | 1998-04-06 | $75.00 | 1998-03-18 |
Maintenance Fee - Patent - Old Act | 6 | 1999-04-06 | $150.00 | 1999-03-24 |
Maintenance Fee - Patent - Old Act | 7 | 2000-04-06 | $150.00 | 2000-03-20 |
Maintenance Fee - Patent - Old Act | 8 | 2001-04-06 | $350.00 | 2001-04-19 |
Maintenance Fee - Patent - Old Act | 9 | 2002-04-08 | $150.00 | 2002-03-25 |
Maintenance Fee - Patent - Old Act | 10 | 2003-04-07 | $400.00 | 2003-05-21 |
Maintenance Fee - Patent - Old Act | 11 | 2004-04-06 | $250.00 | 2004-04-01 |
Maintenance Fee - Patent - Old Act | 12 | 2005-04-06 | $250.00 | 2005-03-21 |
Maintenance Fee - Patent - Old Act | 13 | 2006-04-06 | $250.00 | 2006-03-17 |
Maintenance Fee - Patent - Old Act | 14 | 2007-04-10 | $250.00 | 2007-03-19 |
Maintenance Fee - Patent - Old Act | 15 | 2008-04-07 | $450.00 | 2008-03-17 |
Maintenance Fee - Patent - Old Act | 16 | 2009-04-06 | $450.00 | 2009-03-18 |
Note: Records showing the ownership history in alphabetical order.
Current Owners on Record |
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UNIVERSITY OF CHICAGO |
Past Owners on Record |
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GOLDBERG, LEON I. |