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Patent Summary

(12) Patent: (11) CA 1341625
(21) Application Number: 495255
(54) English Title: RECOMBINANT MAMMALIAN GM-CSF, DNA ENCODING MAMMALIAN GM-SCF AND METHODS OF USE THEREOF
(54) French Title: GM-CSF RECOMBINANT DE MAMMIFERE ADN CODENT POUR CELUI-CIET METHODES D'UTILISATION

Abstracts

English Abstract



This invention provides a DNA sequence coding for a
mammalian granulocyte macrophage colony stimulating factor
(GM-CSF), a method cf obtaining same, vectors and hosts
harboring same. The sequence is useful as a probe for
identifying related sequences, selecting GM-CSF encoding mRNA
from a mixture of mRNAs containing same, and a source of
GM-CSF DNA for expression in an appropriate expression
vector. The GM-CSF protein encoded by the sequence is useful
for stimulating the production of granulocytes and
macrophages from their respective progenitor cells.



Patent Details

(52) Canadian Patent Classification (CPC):
  • 530/13
  • 167/103.2
  • 195/1.235
  • 195/1.34
(51) International Patent Classification (IPC):
  • C12N 15/27 (2006.01)
  • A61K 38/19 (2006.01)
  • C07K 14/535 (2006.01)
  • C12N 15/63 (2006.01)
(72) Inventors (Country):
  • DUNN, ASHLEY ROGER (Australia)
  • GOUGH, NICHOLAS MARTIN (Australia)
  • METCALF, DONALD (Australia)
(73) Owners (Country):
  • RESEARCH CORPORATION TECHNOLOGIES, INC. (United States of America)
(71) Applicants (Country):
  • RESEARCH CORPORATION (United States of America)
(74) Agent: MCFADDEN, FINCHAM
(45) Issued: 2011-12-20
(22) Filed Date: 1985-11-13
(30) Availability of licence: N/A
(30) Language of filing: English

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Cover Page Cover Page 17 1
Abstract Abstract 17 1
Claims Claims 572 16
Description Description 931 23
Drawings Drawings 92 5
Representative Drawing Representative Drawing N/A N/A

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