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|(12) Patent:||(11) CA 2137363|
|(54) English Title:||USE OF ZONA PELLUCIDA GLYCOPROTEINS FOR IMMUNOCONTRACEPTION|
|(54) French Title:||UTILISATION DE GLYCOPROTEINES DE LA MEMBRANE PELLUCIDE A DES FINS D'IMMUNOCONTRACEPTION|
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A vaccine for the immunocontraception of mammals is described. The vaccine consists of zona pellucida antigens and an
adjuvant encapsulated in a liposome delivery system. The liposome delivery system allows for the slow release of antigen resulting
in a prolonged immune response. In particular, after a single injection of the vaccine, levels of anti-zona pellucida antibodies
were detected for up to 22 months. Thus, the vaccine according to the present invention is effective after a single dose and is
therefore very useful in immunocontraceptive protocols.
|(51) International Patent Classification (IPC):||
|(72) Inventors (Country):||
|(73) Owners (Country):||
|(71) Applicants (Country):||
|(74) Agent:||SMART & BIGGAR|
|(86) PCT Filing Date:||1993-06-07|
|(87) PCT Publication Date:||1993-12-23|
|(30) Availability of licence:||N/A|
|(30) Language of filing:||English|
|Patent Cooperation Treaty (PCT):||Yes|
|(86) PCT Filing Number:||PCT/CA1993/000239|
|(87) International Publication Number:||WO1993/025231|
|(85) National Entry:||1994-12-05|
|(30) Application Priority Data:|