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Patent Summary

(12) Patent: (11) CA 2137363
(54) English Title: USE OF ZONA PELLUCIDA GLYCOPROTEINS FOR IMMUNOCONTRACEPTION
(54) French Title: UTILISATION DE GLYCOPROTEINES DE LA MEMBRANE PELLUCIDE A DES FINS D'IMMUNOCONTRACEPTION

Abstracts

English Abstract



A vaccine for the immunocontraception of mammals is described. The vaccine consists of zona pellucida antigens and an
adjuvant encapsulated in a liposome delivery system. The liposome delivery system allows for the slow release of antigen resulting
in a prolonged immune response. In particular, after a single injection of the vaccine, levels of anti-zona pellucida antibodies
were detected for up to 22 months. Thus, the vaccine according to the present invention is effective after a single dose and is
therefore very useful in immunocontraceptive protocols.



Patent Details

(51) International Patent Classification (IPC):
  • A61K 39/00 (2006.01)
  • A61K 9/127 (2006.01)
(72) Inventors (Country):
  • BROWN, ROBERT (Canada)
  • KIMMINS, WARWICK (Canada)
  • MEZEI, MICHAEL (Canada)
  • POHAJDAK, BILL (Canada)
(73) Owners (Country):
  • IMMUNOVACCINE TECHNOLOGIES INC. (Canada)
(71) Applicants (Country):
  • DALHOUSIE UNIVERSITY (Canada)
(74) Agent: SMART & BIGGAR
(45) Issued: 1999-06-15
(86) PCT Filing Date: 1993-06-07
(87) PCT Publication Date: 1993-12-23
Examination requested: 1997-11-03
(30) Availability of licence: N/A
(30) Language of filing: English

(30) Application Priority Data:
Application No. Country Date
892,807 United States of America 1992-06-05

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Cover Page Cover Page 27 1
Abstract Abstract 45 1
Claims Claims 35 2
Description Description 725 19
Drawings Drawings N/A N/A
Representative Drawing Representative Drawing N/A N/A

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