Canadian Patents Database

Patent Summary

(12) Patent Application:	(11) CA 2145545
(54) English Title:	"SENSITIZING HIV-1 INHIBITORS" SENSITIZE HIV INFECTED INDIVIDUALS TO "NON-NUCLEOSIDE HIV TREATMENT DRUGS"
(54) French Title:	SENSIBILISATION DE PERSONNES INFECTEES PAR LE VIH A DES «MEDICAMENTS NON NUCLEOSIDIQUES CONTRE LE VIH» A L'AIDE D'«INHIBITEURS DU VIH-1 A ACTION SENSIBILISANTE»

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English Abstract

Note: The Abstract is shown in the official language in which it was submitted.

The present invention are methods of treating a HIV positive human which Comprises (1) administering to the HIV positive
individual a sensitizingly effective amount of a SENSITIZING HIV-I INHIBITOR until increased sensitivity to a NON-NU-
CLEOSIDE HIV TREATMENT DRUG develops, (2) administering to the HIV positive individual an effective amount of a
NON-NUCLEOSIDE HIV TREATMENT DRUG. An alternative method is a method of treating a HIV positive human which
comprises administering to the HIV positive individual a sensitizingly effective amount of one or more SENSITIZING HIV-I
INHIBITOR concurrently with an effective amount of a NON-NUCLEOSIDE HIV TREATMENT DRUG.

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Patent Details

(51) International Patent Classification (IPC):	A61K 31/55 (2006.01) A61K 31/165 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 45/06 (2006.01)
(72) Inventors (Country):	TARPLEY, WILLIAM GARY (United States of America) DUEWEKE, THOMAS JEROME (United States of America) BATTS, DONALD HERMAN (United States of America)
(73) Owners (Country):	THE UPJOHN COMPANY (United States of America)
(71) Applicants (Country):
(74) Agent:	MACRAE & CO.
(45) Issued:
(86) PCT Filing Date:	1993-09-10
(87) PCT Publication Date:	1994-05-11
(30) Availability of licence:	N/A
(30) Language of filing:	English

Patent Cooperation Treaty (PCT):	Yes
(86) PCT Filing Number:	PCT/US1993/008354
(87) International Publication Number:	WO1994/009781
(85) National Entry:	1995-03-24

(30) Application Priority Data:
Application No. Country Date 967,639 United States of America 1992-10-28 017,119 United States of America 1993-02-12

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View Patent Image	Download Patent Image in PDF Format	Size of Image (KB)	Number of Pages
Cover Page	Cover Page	20	1
Abstract	Abstract	54	1
Claims	Claims	499	13
Description	Description	2,298	56
Drawings	Drawings	N/A	N/A
Representative Drawing	Representative Drawing	N/A	N/A