USE OF MACROLIDES IN PEST CONTROL

UTILISATION DE MACROLIDES DANS LA LUTTE CONTRE LES PARASITES

English Abstract

There is now described a method of controlling pests with macrolide compounds;
more specifically: A) a method of controlling
pests in and on transgenic crops of useful plants, such as, for example, in
crops of maize, cereals, soya beans, tomatoes, cotton, potatoes,
rice and mustard, with a macrolide compound, characterized in that a
pesticidal composition comprising a macrolide compound in free
form or in agrochemically useful salt form and at least one auxiliary is
applied to the pests or their environment, in particular to the crop
plant itself; B) a method of protecting plant propagation material and plant
organs formed at a later point in time from attack by pests,
characterized in that a pesticide comprising, as pesticidally active compound,
at least one macrolide compound as active ingredient and at
least one auxiliary in close spatial proximity to, or spatially together with,
planting or applying the propagation material is employed to the
site of planting or sowing; C) a method of controlling wood pests and molluscs
with a macrolide compound, wherein a pesticidally active
amount of a pesticide comprising, as pesticidally active compound, at least
one macrolide, in free form or agrochemically utilizable salt
form, as active ingredient and at least one auxiliary is applied to the pests
or their environment; the corresponding use of these compounds,
corresponding pesticides whose active ingredient is selected from amongst
these compounds, a method for the preparation and the use of
these compositions, and plant propagation material which is protected in this
manner from attack by pests.

French Abstract

L'invention concerne un procédé de lutte contre les parasites avec des composés de macrolides; plus spécifiquement: A) un procédé de lutte contre les parasites dans et sur des récoltes transgéniques de plantes utiles, telles que par exemple, du maïs, des céréales, du soja, des tomates, du coton, des pommes de terre, du riz et de la moutarde, avec un composé de macrolide, le procédé se caractérisant par l'application d'une composition pesticide comprenant un composé de macrolide sous forme libre ou sous forme de sel utilisable dans l'agrochimie et au moins un composé auxiliaire, sur les parasites ou leur milieu, notamment sur la plante elle-même; B) un procédé de protection, de matières de multiplication de plantes et d'organes végétaux formés ultérieurement, contre des attaques par des parasites, le procédé se caractérisant par le fait qu'on utilise sur le site de plantation ou de semis un pesticide comprenant, comme composé actif pesticide, au moins un composé de macrolide comme ingrédient actif et au moins un composé auxiliaire dans un espace proche ou dans le même espace que la matière de multiplication au moment où elle est plantée ou appliquée; C) un procédé de lutte contre les parasites du bois et les mollusques avec un composé de macrolide, le procédé consistant à appliquer une quantité active comme pesticide d'un pesticide comprenant, comme composé pesticide, au moins un macrolide, sous forme libre ou sous forme de sel utilisable dans l'agrochimie comme ingrédient actif et au moins un composé auxiliaire, sur les parasites ou leur milieu; l'invention comprend également l'utilisation correspondante de ces composés, des pesticides correspondants dont l'ingrédient actif est sélectionné parmi ces composés, un procédé de préparation et d'utilisation de ces compositions et une matière de multiplication de plantes protégée de cette façon contre les attaques de parasites.

Claims

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1. Method of protecting a seed and plant organs which
grow at a later point in time against attack by a pest
selected from the class Insecta, class Arachnida and class
Nematoda, which comprises treating the seed with a
pesticidal composition comprising emamectin, abamectin or
spinosad or an agrochemically utilisable salt thereof and at
least one auxillary.

2. Method of controlling a pest selected from the
group consisting of class Insecta, class Arachnida and
class Nematoda in crop plants, which comprises treating a
seed of the crop plant with a pesticidal composition
comprising emamectin, abamectin or spinosad in free form or
in agrochemically utilisable salt form and at least one
auxiliary.

3. The method according to claim 1 or 2, wherein the
seed is treated prior to planting or sowing.

4. A method of controlling a pest selected from the
group consisting of class Insecta, class Arachnida and
class Nematoda in a cultivated plant which comprises

treating plant seed with a pesticidal composition
comprising emamectin, abamectin or spinosad or an
agrochemically utilisable salt thereof and at least one
auxiliary,

planting or sowing the treated seed, and
achieving control of pests selected from
representatives of the class Insecta, class Arachnida and
class Nematoda at the site of planting or sowing.



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5. The method according to any one of claims 1 to 4,
wherein the pesticidal composition comprises abamectin and
at least one auxiliary.

6. The method according to any one of claims 1 to 5,
wherein the pest is from the class Nematoda.

7. The method according to any one of claims 1 to 6,
wherein the pesticidal composition is derived from a
suspension concentrate, emulsifiable concentrate, dust,
granule or wettable powder.

8. The method according to any one of claims 1 to 7,
wherein the seed is selected from cereals, cotton, soya
beans, oilseed rape, vegetables, potatoes, sunflowers and
sugar beet.

9. The method according to claim 8, wherein the
cereal is selected from rice, maize and sorghum.

10. The method according to any one of claims 1 to 9,
wherein the seed is a genetically modified seed containing
one or more genes expressing pesticidal resistance.

11. The method according to any one of claims 1 to 10,
wherein the pesticidal composition further comprises a
compound selected from azoxystrobin; bitertanol; carboxin;
Cu2O; cymoxanil; cyproconazole; cyprodinil; dichiofluamid;
difenoconazole; diniconazole; epoxiconazole; fenpiclonil;
fludioxonil; fluquiconazole; flusilazole; flutriafol;
furalaxyl; guazatin; hexaconazole; hymexazol; imazalil;
imibenconazole; ipconazole; kresoxim-methyl; mancozeb;
metalaxyl; R-metalaxyl; metconazole; oxadixyl, pefurazoate;
penconazole; pencycuron; prochloraz; propiconazole;
pyroquilone; SSF-109; spiroxamin; tebuconazole;



-147-

thiabendazole; tolifluamide; triazoxide; triadimefon;
triadimenol; triflumizole; triticonazole and uniconazole.
12. The method according to any one of claims 1 to 11,
wherein the pesticidal composition further comprises a
compound selected from NI-25, TI-304, TI-435, MTI-446,
fipronil, thiacloprid, imidacloprid, thiamethoxam and
tefluthrin.

13. A pesticidal composition selected from suspension
concentrate and wettable powder, which composition comprises
emamectin, abamectin or spinosad or an agrochemically
utilisable salt thereof and at least one auxillary and
optionally one or more further pesticides.

14. The composition according to claim 13, wherein the
pesticidal composition comprises abamectin, one or more
further pesticides and at least one auxiliary.

15. The composition according to either claim 13 or
claim 14 wherein the one or more further pesticides are
selected from azoxystrobin; bitertanol; carboxin; Cu2O;
cymoxanil; cyproconazole; cyprodinil; dichlofluamid;
difenoconazole; diniconazole; epoxiconazole; fenpiclonil;
fludioxonil; fluquiconazole; flusilazole; flutriafol;
furalaxyl; guazatin; hexaconazole; hymexazol; imazalil;
imibenconazole; ipconazole; kresoxim-methyl; mancozeb;
metalaxyl; R-metalaxyl; metconazole; oxadixyl, pefurazoate;
penconazole; pencycuron; prochloraz; propiconazole;
pyroquilone; SSF-109; spiroxamin; tebuconazole;
thiabendazole; tolifluamide; triazoxide; triadimefon;
triadimenol; triflumizole; triticonazole, uniconazole,
NI-25, TI-304, TI-435, MTI-446, fipronil, thiacloprid,
imidacloprid, thiamethoxam, spinosad and tefluthrin.



-148-

16. Use of the composition defined in any one of
claims 13 to 15 for seed dressing.

17. Use of the composition defined in any one of
claims 13 to 15 for controlling a representative of the
class Nematoda against attack on a seed and plant organs
which grow at a later point in time comprising treating the
seed with the composition prior to sowing or planting.

Description

li
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Use of macrolides in pest control

The present invention relates to a method of
controlling pests with macrolide compounds; more
specifically to

(A) a novel method of controlling pests in and on
transgenic crops of useful plants with a macrolide compound;
(B) method of protecting plant propagation
material and plant organs formed at a later point in time
from attack by pests with such a macrolide compound; and
(C) a method of controlling wood pests and
molluscs with a macrolide compound.

Certain pest control methods are proposed in the
literature. However, these methods are not fully
satisfactory in the field of pest control, which is why

there is a demand for providing further methods for
controlling and combating pests, in particular insects and
representatives of the order Acarina, or for protecting
plants, especially crop plants. This object is achieved
according to the invention by providing the present method.

According to one aspect of the present invention,
there is provided a method of protecting seed which is to be
grown at a later point in time against attack by pests
selected from insects, representatives of order Acarina and
representatives of class Nematoda; wherein said method

comprises treating the seed, prior to sowing, with a
pesticidal formulation selected from a wettable powder and a
suspension concentrate, the formulation comprising as active
ingredient one or more compound selected from Abamectin,
Emamectin and Spinosad in free form or in agrochemically
utilizable salt form.


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(A) A first aspect of the present invention
therefore relates to a method of controlling pests in crops
of transgenic useful plants, such as, for example, in crops
of maize, cereals, soya beans, tomatoes, cotton, potatoes,
rice and mustard, characterized in that a pesticidal
composition comprising a macrolide compound, in particular
abamectin, in free form or in agrochemically useful salt
form and at least one auxiliary is applied to the pests or
their environment, in particular to the crop plant itself;

to the use of the composition in question and to propagation
material of transgenic plants which has been treated with
it.

Surprisingly, it has now emerged that the use of a
macrolide compound for controlling pests on transgenic

useful plants which contain - for instance - one or more
genes expressing a pesticidally, particularly
insecticidally, acaricidally, nematocidally or fungicidally
active ingredient, or which are tolerant against herbicides,
has a synergistic effect. It is highly surprising that the
use of a macrolide compound in combination with a transgenic
plant exceeds the additive effect, to be expected in
principle, on the pests to be controlled and thus extends
the range of action of the macrolide compound and of the
active principle expressed by the transgenic plant in

particular in two respects:

In particular, it has been found, surprisingly,
that within the scope of invention (A) the pesticidal
activity of a macrolide compound in combination with the
effect expressed by the


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transgenic useful plant, is not only additive in comparison with the
pesticidal activities of the
macrolide compound alone and of the transgenic crop plant alone, as can
generally be
expected, but that a synergistic effect is present. The term "synergistic",
however, is in no
way to be understood in this connection as being restricted to the pesticidal
activity, but the
term also refers to other advantageous properties of the method according to
the invention
compared with the macrolide compound alone and the transgenic useful plant
alone.
Examples of such advantageous properties which may be mentioned are: extension
of the
pesticidal spectrum of action to other pests, for example to resistant
strains; reduction in the
application rate of the macrotide compound, or sufficient control of the pests
with the aid of
the compositions according to the invention even at an application rate of the
macrolide
compound alone and the transgenic useful plant alone are entirely ineffective;
enhanced
crop safety; improved quality of produce such as higher content of nutrient or
oil, better fiber
quality, enhanced shelf life, reduced content of toxic products such as
mycotoxins, reduced
content of residues or unfavorable constituents of any kind or better
digestability; improved
tolerance to unfavorable temperatures, draughts or salt content of water;
enhanced
assimilation rates such as nutrient uptake, water uptake and photosynthesis;
favorable crop
properties such as altered leaf aerea, reduced vegetative growth, increased
yields,
favorable seed shape/seed thickness or germination properties, altered
colonialisation by
saprophytes or epiphytes, reduction of senescense, improved phytoalexin
production,
improved of accelerated ripening, flower set increase, reduced boll fall and
shattering,
better attraction to beneficials and predators, increased pollination, reduced
attraction to
birds; or other advantages known to those skilled in the art.

The macrolide compounds used according to the inventions part (A), (B) and (C)
are known
to those skilled in the art. They are the classes of substances which are
disclosed as
milbemycins and avermectins, for example in US-P-4 310 519, US-P-5 077 298,
German
Offenlegungsschrift 2 717 040 or US-P-4 427 663. These macrolides are also to
be
understood as meaning, in accordance with the invention, the derivatives of
these
substances, that is, for example, milbemycin oxime, moxidectin, ivermectin,
abamectin,
emamectin and doramectin, and also spinosyns of the formula


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ORS
R4
Ra
2O ORZ (III),
O
R6 O

R,
in which R1, R2, R3, R4, R5 and R6 independently of one another are hydrogen
or a sub-
stituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl or
heterocyclyl group and the
substructures A,and B independently of one another denote that the two carbon
atoms, to
which each of these substructures is bonded, are linked by a single bond, by a
double bond
or by a single bond and an epoxy bridge, in free form or, if appropriate, in
agrochemically
utilizable salt form.

Within the scope of invention (A) abamectin is preferred. Abamectin is a
mixture of aver-
mectin B,, and avermectin Bib and is described, for example, in The Pesticide
Manual,
10"'Ed. (1994), The British Crop Protection Council, London, page 3.

Also preferred within the scope of invention (A) is emamectin, which is 4"-De-
oxy-4"-epi-N-methylamino avermectin Bib/B,,, known from US-P-4,874,749 and as
MK-244
described in Journal of Organic Chemistry, Vol. 59 (1994), pages 7704-7708.
Agro-
chemically especially useful salts of emamectin are described in US-P-5,288,71
0.

Also preferred within the scope of invention (A) is the group of compounds
consisting of the
spinosyns and their derivatives; the group of compounds consisting of the
naturally
occurring spinosyns; or the group of compounds consisting of the derivatives
of the
naturally occurring spinosyns. Preferably, the active ingredient may comprise,
within the
scope of the subject-matter of the invention (A), spinosyn A; spinosyn D; or a
mixture
composed of spinosyn A and spinosyn D; especially preferred is spinosad.
spinosad is
known from the The Pesticide Manual", 11"' Ed. (1997), The British Crop
Protection
Council, London, United Kingdom, pages 1272-1273.

The agrochemically compatible salts of the macrolide compounds are, for
example, acid
addition salts of inorganic and organic acids, in particular of hydrochloric
acid, hydrobromic
acid, sulfuric acid, nitric acid, perchioric acid, phosphoric acid, formic
acid, acetic acid, tri-
fluoroacetic acid, oxalic acid, malonic acid, toluenesulfonic acid or benzoic
acid. Preferred


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within the scope of the present invention is a composition known per se which
comprises,
as active ingredient, abamectin or spinosad in the free form, and emamectin as
the
benzoate salt.

The transgenic plants used according to the invention (A) are plants, or
propagation
material thereof, which are transformed by means of recombinant DNA technology
in such a
way that they are - for instance - capable of synthesizing selectively acting
toxins as are
known, for example, from toxin-p roducinginvertebrates, especially of the
phylum
Arthropoda, as can be obtained from Bacillus thuringiensis strains; or as are
known from
plants, such as lectins; or in the alternative capable of expressing a
herbicidal or fungicidal
resistance. Examples of such toxins, or transgenic plants which are capable of
synthesizing
such toxins, have been disclosed, for example, in EP-A-0 374 753, WO 93/07278,
WO 95/34656, EP-A-0 427 529 and EP-A-451 878.

The methods for generating such transgenic plants are widely known to those
skilled in the
art and described, for example, in the publications mentioned above.

The toxins which can be expressed by such transgenic plants include, for
example, toxins,
such as proteins which have insecticidal properties and which are expressed by
transgenic
plants, for example Bacillus cereus proteins or Bacillus popliae proteins; or
Bacillus
thuringiensis endotoxins (B.t.), such as CryIA(a), CrylA(b), CrylA(c), CryllA,
CryllIA, CrylIIB2
orCytA; VIP1; VIP2; VIP3; or insecticidal proteins of bacteria colonising
nematodes like
Photorhabdus spp or Xenorhabdus spp such as Photorhabdus luminescens,
Xenorhabdus
nematophilus etc.; proteinase inhibitors, such as trypsin inhibitors, serine
protease
inhibitors, patatin, cystatin, papain inhibitors; ribosome-inactivating
proteins (RIP), such as
ricin, maize RIP, abrin, luffin, saporin or bryodin; plant lectins such as pea
lectins, barley
lectins or snowdrop lectins; or agglutinins; toxins produced by animals, such
as scorpion
toxins, spider venoms, wasp venoms and other insect-specific neurotoxins;
steroid
metabolism enzymes, such as 3-hydroxysteroid oxidase, ecdysteroid UDP-glycosyl
transferase, cholesterol oxidases, ecdysone inhibitors, HMG-COAreductase, ion
channel
blockers such as sodium and calcium, juvenile hormone esterase, diuretic
hormone
receptors, stilbene synthase, bibenzyl synthase, chitinases and glucanases.

Examples of known transgenic plants which comprise one or more genes which
encode
insecticidal resistance and express one or more toxins are the following:
KnockOut


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(maize), YieldGard (maize); NuCOTN 33B (cotton), Boligard (cotton), NewLeaf

(potatoes), NatureGard and Protecta .

The following table comprises further examples of targets and principles and
crop
phenotypes of transgenic crops which show tolerance against pests mainly
insects, mites,
nematodes, virus, bacteria and diseases or are tolerant to specific herbicides
or classes of
herbicides.

Table Al: Crop: Maize

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transterase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitnles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or suitosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenyipyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as
Sulfonylureas
Dimboa biosynthesis (Bxl gene) Helminthosporium turcicum,
Rhopalosiphum maydis, Diplodia
maydis, Ostrinia nubilalis, lepidoptera sp.
CMIII (small basic maize seed peptide plant pathogenes eg. fusarium,
altemaria, scierotina
Corn- SAFP (zeamatin) plant pathogenes eg. fusarium,
altemaria, scierotina, rhizoctonia,
chaetomium,phycomyces
Hml gene Cochliobulus
Chitinases plant pathogenes
Glucanases plant pathogenes
Coat proteins viruses such as maize dwarf mosaic
virus, maize chlorotic dwarf virus
Bacillus thuringiensis toxins, VIP 3, lepidoptera, coleoptera, diptera,
Bacillus cereus toxins, Photorabdus and nematodes, eg. ostrinia nubilalis,
Xenorhabdus toxins heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,
sesamia sp., black cutworm, asian corn
borer,weevils
3- Hydroxysteroid oxidase lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,
sesamia sp., black cutworm, asian corn
borer, weevils
Peroxidase lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,
sesamia sp., black cutworm, asian corn


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

borer, weevils
Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, diptera,
aminopeptidase inhibitor (LAPI) nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,
sesamia sp., black cutworm, asian corn
borer, weevils
Limonene synthase corn rootworms
Lectines lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,
sesamia sp., black cutworm, asian corn
borer, weevils
Protease Inhibitors eg. cystatin, patatin, weevils, corn rootworm
virgiferin, CPTI
ribosome inactivating protein lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,
sesamia sp., black cutworm, asian corn
borer, weevils
maize 5C9 polypeptide lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,
sesamia sp., black cutworm, asian corn
borer, weevils
HMG-CoA reductase lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, corn rootworms,


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Effected target or expressed principle(s) Crop phenotype I Tolerance to

sesamia sp., black cutworm, asian corn
borer, weevils

Table A2: Crop Wheat

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or suifosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as
Sulfonytureas
Antifungal polypeptide AIyAFP plant pathogenes eg septoria and


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

fusarioum
glucose oxidase plant pathogenes eg. fusarium, septoria
pyrrolnitrin synthesis genes plant pathogenes eg. fusarium, septoria
serine/threonine kinases plant pathogenes eg. fusarium, septoria
and other diseases
Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria
polypeptide and other diseases
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases plant pathogenes
Glucanases plant pathogenes
double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, coleoptera, diptera,
Bacillus cereus toxins, Photorabdus and nematodes,
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, coleoptera, diptera,
nematodes,
Peroxidase lepidoptera, coleoptera, diptera,
nematodes,
Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, diptera,
aminopeptidase inhibitor nematodes,
Lectines lepidoptera, coleoptera, diptera,
nematodes, aphids
Protease Inhibitors eg. cystatin, patatin, lepidoptera, coleoptera, diptera,
virgiferin, CPTI nematodes, aphids
ribosome inactivating protein lepidoptera, coleoptera, diptera,
nematodes, aphids
HMG-CoA reductase lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

sesamia sp., black cutworm, asian corn
borer, weevils

Table A3: Crop Barley

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazoiopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or suifosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as
Sulfonylureas
Antifungal polypeptide AIyAFP plant pathogenes eg septoria and


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Effected target or expressed principle(s) Crop phenotype I Tolerance to

fusarioum
glucose oxidase plant pathogenes eg. fusarium, septoria
pyrrolnitrin synthesis genes plant pathogenes eg. fusarium, septoria
serine/threonine kinases plant pathogenes eg. fusarium, septoria
and other diseases
Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria
polypeptide and other diseases
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases plant pathogenes
Glucanases plant pathogenes
double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, coleoptera, diptera,
Bacillus cereus toxins, Photorabdus and nematodes,
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, coleoptera, diptera,
nematodes,
Peroxidase lepidoptera, coleoptera, diptera,
nematodes,
Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, diptera,
aminopeptidase inhibitor nematodes,
Lectines lepidoptera, coleoptera, diptera,
nematodes, aphids
Protease Inhibitors eg. cystatin, patatin, lepidoptera, coleoptera, diptera,
virgiferin, CPTI nematodes, aphids
ribosome inactivating protein lepidoptera, coleoptera, diptera,
nematodes, aphids
HMG-CoA reductase lepidoptera, coleoptera, diptera,
nematodes, aphids

Table A4: Crop Rice


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Acetolactate synthase (ALS) Sulfonylureas, imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachiortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or suifosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as
Sulfonylureas
Antifungal polypeptide AIyAFP plant pathogenes
glucose oxidase plant pathogenes
pyrrolnitrin synthesis genes plant pathogenes
serine/threonine kinases plant pathogenes
Phenylalanine ammonia lyase (PAL) plant pathogenes eg bacterial leaf blight
and rice blast, inducible


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

phytoalexins plant pathogenes eg bacterial leaf blight
and rice blast
B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight
and rice blast
receptor kinase plant pathogenes eg bacterial leaf blight
and rice blast
Hypersensitive response eliciting plant pathogenes
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases plant pathogenes eg bacterial leaf blight
and rice blast
Glucanases plant pathogenes
double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera eg. stemborer, coleoptera eg
Bacillus cereus toxins, Photorabdus and rice water weevil, diptera, rice
hoppers
Xenorhabdus toxins eg brown rice hopper
3- Hydroxysteroid oxidase lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper
Peroxidase lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper
Aminopeptidase inhibitors eg. Leucine lepidoptera eg. stemborer, coleoptera eg
aminopeptidase inhibitor rice water weevil, diptera, rice hoppers
eg brown rice hopper
Lectines lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper

Protease Inhibitors, lepidoptera eg. stemborer, coleoptera eg


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

rice water weevil, diptera, rice hoppers
eg brown rice hopper
ribosome inactivating protein lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper
HMG-CoA reductase lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper

Table A5: Crop Soya

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transf erase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopytate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Antifungal polypeptide AIyAFP bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
oxalate oxidase bacterial and fungal pathogens such as
fusarium, sclerotinia, stemrot
glucose oxidase bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
pyrrolnitrin synthesis genes bacterial and fungal pathogens such as
fusarium. sclerotinia, stemrot
serine/threonine kinases bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as
fusarium, sclerotinia, stemrot
phytoalexins plant pathogenes eg bacterial leaf blight
and rice blast
B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight
and rice blast
receptor kinase bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
Hypersensitive response eliciting plant pathogenes
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
Glucanases bacterial and fungal pathogens such as
fusarium, sclerotinia, stemrot


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

double stranded ribonuclease viruses such as BPMV and SbMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, coleoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, coleoptera, aphids
Peroxidase lepidoptera, coleoptera, aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, aphids
aminopeptidase inhibitor
Lectines lepidoptera, coleoptera, aphids
Protease Inhibitors eg virgiferin lepidoptera, coleoptera, aphids
ribosome inactivating protein lepidoptera, coleoptera, aphids
HMG-CoA reductase lepidoptera, coleoptera, aphids

Bamase nematodes eg root knot nematodes and
cyst nematodes
Cyst nematode hatching stimulus cyst nematodes
Antifeeding principles nematodes eg root knot nematodes and
cyst nematodes

Table A6: Crop Potatoes

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoies such as Isoxaflutol or


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

(HPPD) Isoxachiortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitnies such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol blackspot bruise
oxidase antisense
Metallothionein bacterial and fungal pathogens such as
phytophtora
Ribonuclease Phytophtora, Verticillium, Rhizoctonia
Antifungal polypeptide AIyAFP bacterial and fungal pathogens such as
phytophtora
oxalate oxidase bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
glucose oxidase bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
pyrrolnitrin synthesis genes bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
serine/threonine kinases bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
Cecropin B bacteria such as corynebacterium
sepedonicum, Erwinia carotovora
Phenylalanine ammonia Iyase (PAL) bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
phytoalexins bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
B-1,3-glucanase antisense bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
receptor kinase bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
Hypersensitive response eliciting bacterial and fungal pathogens such as
polypeptide Phytophtora, Verticillium, Rhizoctonia
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
Bamase bacterial and fungal pathogens such as
Phytophtora, Verticillium,
Rhizoctonia
Disease resistance response gene 49 bacterial and fungal pathogens such as
Phytophtora, Verticillium,
Rhizoctonia
trans aldolase antisense blackspots
Glucanases bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
double stranded ribonuclease viruses such as PLRV, PVY and TRV
Coat proteins viruses such as PLRV, PVY and TRV
17kDa or 60 kDa protein viruses such as PLRV, PVY and TRV
Nuclear inclusion proteins eg. a or b viruses such as PLRV, PVY and TRV


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Pseudoubiquitin viruses such as PLRV, PVY and TRV
Replicase viruses such as PLRV, PVY and TRV
Bacillus thuringiensis toxins, VIP 3, coleoptera eg colorado potato beetle,
Bacillus cereus toxins, Photorabdus and aphids
Xenorhabdus toxins
3- Hydroxysteroid oxidase coleoptera eg colorado potato beetle,
aphids
Peroxidase coleoptera eg colorado potato beetle,
aphids
Aminopeptidase inhibitors eg. Leucine coleoptera eg colorado potato beetle,
aminopeptidase inhibitor aphids
stilbene synthase coleoptera eg colorado potato beetle,
aphids
Lectines coleoptera eg colorado potato beetle,
aphids
Protease Inhibitors eg cystatin, patatin coleoptera eg colorado potato beetle,
aphids

ribosome inactivating protein coleoptera eg colorado potato beetle,
aphids
HMG-CoA reductase coleoptera eg colorado potato beetle,
aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
Antifeeding principles nematodes eg root knot nematodes and
cyst nematodes

Table A7: Crop Tomatoes

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol blackspot bruise
oxidase antisense
Metallothionein bacterial and fungal pathogens such as
phytophtora
Ribonuclease Phytophtora, Verticillium, Rhizoctonia
Antifungal polypeptide AIyAFP bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

etc.
oxalate oxidase bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
glucose oxidase bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
pyrroinitrin synthesis genes bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
serine/threonine kinases bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Cecropin B bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 leaf mould
Osmotin altemaria solani
Alpha Hordothionin bacteria
Systemin bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

etc.
Polygalacturonase inhibitors bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Prf regulatory gene bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
12 Fusarium resistance locus fusarium
phytoalexins bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
B-1,3-glucanase antisense bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
receptor kinase bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Hypersensitive response eliciting bacterial and fungal pathogens such as
poiypeptide bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Bamase bacterial and fungal pathogens such as
bacterial speck, fusarium, soft
rot, powdery mildew, crown rot,
leaf mould etc.
Glucanases bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
double stranded ribonuclease viruses such as PLRV, PVY and ToMoV
Coat proteins viruses such as PLRV, PVY and ToMoV
17kDa or 60 kDa protein viruses such as PLRV, PVY and ToMoV
Nuclear inclusion proteins eg. a or b or viruses such as PLRV, PVY and ToMoV
Nucleoprotein TRV
Pseudoubiquitin viruses such as PLRV, PVY and ToMoV
Replicase viruses such as PLRV, PVY and ToMoV
Bacillus thuringiensis toxins, VIP 3, lepidoptera eg heliothis, whiteflies
Bacillus cereus toxins, Photorabdus and aphids
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera eg heliothis, whiteflies
aphids
Peroxidase lepidoptera eg heliothis, whiteflies
aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera eg heliothis, whiteflies
aminopeptidase inhibitor aphids
Lectines lepidoptera eg heliothis, whiteflies
aphids
Protease Inhibitors eg cystatin, patatin lepidoptera eg heliothis, whiteflies
aphids
ribosome inactivating protein lepidoptera eg heliothis, whiteflies
aphids
stilbene synthase lepidoptera eg heliothis, whiteflies


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

aphids
HMG-CoA reductase lepidoptera eg heliothis, whiteflies
aphids
Cyst nematode hatching stimulus cyst nematodes
Barnase nematodes eg root knot nematodes and
cyst nematodes
Antifeeding principles nematodes eg root knot nematodes and
cyst nematodes

Table A8: Crop Peppers

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens
oxidase antisense
Metaliothionein bacterial and fungal pathogens
Ribonuclease bacterial and fungal pathogens
Antifungal polypeptide AIyAFP bacterial and fungal pathogens
oxalate oxidase bacterial and fungal pathogens
glucose oxidase bacterial and fungal pathogens
pyrrolnitrin synthesis genes bacterial and fungal pathogens
serine/threonine kinases bacterial and fungal pathogens
Cecropin B bacterial and fungal pathogens rot, leaf
mould etc.

Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens
Osmotin bacterial and fungal pathogens
Alpha Hordothionin bacterial and fungal pathogens
Systemin bacterial and fungal pathogens
Polygalacturonase inhibitors bacterial and fungal pathogens
Prf regulatory gene bacterial and fungal pathogens
12 Fusarium resistance locus fusarium
phytoalexins bacterial and fungal pathogens
B-1,3-glucanase antisense bacterial and fungal pathogens
receptor kinase bacterial and fungal pathogens
Hypersensitive response eliciting bacterial and fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Chitinases bacterial and fungal pathogens
Bamase bacterial and fungal pathogens
Glucanases bacterial and fungal pathogens
double stranded ribonuclease viruses such as CMV, TEV
Coat proteins viruses such as CMV, TEV
17kDa or 60 kDa protein viruses such as CMV, TEV
Nuclear inclusion proteins eg. a or b or viruses such as CMV, TEV
Nucleoprotein
Pseudoubiquitin viruses such as CMV, TEV
Replicase viruses such as CMV, TEV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, whiteflies aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, whiteflies aphids
Peroxidase lepidoptera, whiteflies aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, whiteflies aphids
aminopeptidase inhibitor
Lectines lepidoptera, whiteflies aphids
Protease Inhibitors eg cystatin, patatin lepidoptera, whiteflies aphids
ribosome inactivating protein lepidoptera, whiteflies aphids
stilbene synthase lepidoptera, whiteflies aphids
HMG-CoA reductase lepidoptera, whitef lies aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
Antifeeding principles nematodes eg root knot nematodes and
cyst nematodes

Table A9: Crop Grapes

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Triazolopyrimidines,
Pyrimidyioxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachiortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitnles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like
oxidase antisense Botrytis and powdery mildew
Metallothionein bacterial and fungal pathogens like
Botrytis and powdery mildew
Ribonuclease bacterial and fungal pathogens like
Botrytis and powdery mildew
Antifungal polypeptide AIyAFP bacterial and fungal pathogens like
Botrytis and powdery mildew


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

oxalate oxidase bacterial and fungal pathogens like
Botrytis and powdery mildew
glucose oxidase bacterial and fungal pathogens like
Botrytis and powdery mildew
pyrrolnitrin synthesis genes bacterial and fungal pathogens like
Botrytis and powdery mildew
serine/threonine kinases bacterial and fungal pathogens like
Botrytis and powdery mildew
Cecropin B bacterial and fungal pathogens like
Botrytis and powdery mildew
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens like
Botrytis and powdery mildew
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like
Botrytis and powdery mildew
Osmotin bacterial and fungal pathogens like
Botrytis and powdery mildew
Alpha Hordothionin bacterial and fungal pathogens like
Botrytis and powdery mildew
Systemin bacterial and fungal pathogens like
Botrytis and powdery mildew
Polygalacturonase inhibitors bacterial and fungal pathogens like
Botrytis and powdery mildew
Prf regulatory gene bacterial and fungal pathogens like
Botrytis and powdery mildew
phytoalexins bacterial and fungal pathogens like
Botrytis and powdery mildew
B-1,3-giucanase antisense bacterial and fungal pathogens like
Botrytis and powdery mildew

receptor kinase bacterial and fungal pathogens like
Botrytis and powdery mildew
Hypersensitive response eliciting bacterial and fungal pathogens like


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

polypeptide Botrytis and powdery mildew
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens like
Botrytis and powdery mildew
Bamase bacterial and fungal pathogens like
Botrytis and powdery mildew
Glucanases bacterial and fungal pathogens like
Botrytis and powdery mildew
double stranded ribonuclease viruses
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or viruses
Nucleoprotein
Pseudoubiquitin viruses
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids
Peroxidase lepidoptera, aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids
aminopeptidase inhibitor
Lectines lepidoptera, aphids
Protease Inhibitors eg cystatin, patatin lepidoptera, aphids
ribosome inactivating protein lepidoptera, aphids
stilbene synthase lepidoptera, aphids, diseases
HMG-CoA reductase lepidoptera, aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes or general diseases
CBI root knot nematodes


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Antifeeding principles nematodes eg root knot nematodes or
root cyst nematodes

Table Al0: crop Oil Seed rape

Effected target or expressed principle(s) Crop phenotype J Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Suitonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

oxidase antisense Cylindrosporium, Phoma, Sclerotinia
Metallothionein bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Ribonuclease bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Antifungal polypeptide AIyAFP bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
oxalate oxidase bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
glucose oxidase bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
pyrrolnitrin synthesis genes bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
serine/threonine kinases bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Cecropin B bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Osmotin bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Alpha Hordothionin bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Systemin bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Polygalacturonase inhibitors bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Prf regulatory gene bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
phytoalexins bacterial and fungal pathogens like


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Cylindrosporium, Phoma, Sclerotinia
B-1,3-glucanase antisense bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
receptor kinase bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Hypersensitive response eliciting bacterial and fungal pathogens like
polypeptide Cylindrosporium, Phoma, Scierotinia
Systemic acquires resistance. (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Bamase bacterial and fungal pathogens like
Cylindrosporium, Phoma,
Sclerotinia, nematodes
Giucanases bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
double stranded ribonuclease viruses
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or viruses
Nucleoprotein
Pseudoubiquitin viruses
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids
Peroxidase lepidoptera, aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids
aminopeptidase inhibitor
Lectines lepidoptera, aphids
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

CPTI
ribosome inactivating protein lepidoptera, aphids
stilbene synthase lepidoptera, aphids, diseases
HMG-CoA reductase lepidoptera, aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A11: Crop Brassica vegetable (cabbage, brussel sprouts, broccoli etc.)
Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens
oxidase antisense
Metallothionein bacterial and fungal pathogens
Ribonuclease bacterial and fungal pathogens
Antifungal polypeptide AIyAFP bacterial and fungal pathogens
oxalate oxidase bacterial and fungal pathogens
glucose oxidase bacterial and fungal pathogens
pyrrolnitrin synthesis genes bacterial and fungal pathogens
serine/threonine kinases bacterial and fungal pathogens
Cecropin B bacterial and fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens
Osmotin bacterial and fungal pathogens
Alpha Hordothionin bacterial and fungal pathogens
Systemin bacterial and fungal pathogens
Polygalacturonase inhibitors bacterial and fungal pathogens
Prf regulatory gene bacterial and fungal pathogens
phytoalexins bacterial and fungal pathogens
B-1,3-glucanase antisense bacterial and fungal pathogens
receptor kinase bacterial and fungal pathogens
Hypersensitive response eliciting bacterial and fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Barnase bacterial and fungal pathogens
Glucanases bacterial and fungal pathogens
double stranded ribonuclease viruses
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or viruses
Nucleoprotein
Pseudoubiquitin viruses
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids
Peroxidase lepidoptera, aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids
aminopeptidase inhibitor
Lectines lepidoptera, aphids
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids
CPTI
ribosome inactivating protein lepidoptera, aphids
stilbene synthase lepidoptera, aphids, diseases
HMG-CoA reductase lepidoptera, aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes


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Table A12 : Crop Pome fruits eg apples, pears

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transf erase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihaio-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or suifosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or suifosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like
oxidase antisense apple scab or fireblight
Metallothionein bacterial and fungal pathogens like
apple scab or fireblight
Ribonuclease bacterial and fungal pathogens like


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

apple scab or fireblight
Antifungal polypeptide AIyAFP bacterial and fungal pathogens like
apple scab or fireblight
oxalate oxidase, bacterial and fungal pathogens like
apple scab or fireblight
glucose oxidase bacterial and fungal pathogens like
apple scab or fireblight
pyrrolnitrin synthesis genes bacterial and fungal pathogens like
apple scab or fireblight
serine/threonine kinases bacterial and fungal pathogens like
apple scab or fireblight
Cecropin B bacterial and fungal pathogens like
apple scab or fireblight
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens like
apple scab or fireblight
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like
apple scab or fireblight
Osmotin bacterial and fungal pathogens like
apple scab or fireblight
Alpha Hordothionin bacterial and fungal pathogens like
apple scab or fireblight
Systemin bacterial and fungal pathogens like
apple scab or fireblight
Polygalacturonase inhibitors bacterial and fungal pathogens like
apple scab or fireblight
Prt regulatory gene bacterial and fungal pathogens like
apple scab or fireblight
phytoalexins bacterial and fungal pathogens like
apple scab or fireblight
B-1,3-glucanase antisense bacterial and fungal pathogens like
apple scab or fireblight
receptor kinase bacterial and fungal pathogens like


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

apple scab or fireblight
Hypersensitive response eliciting bacterial and fungal pathogens like
polypeptide apple scab or fireblight

Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial and fungal pathogens like
apple scab or fireblight
Lysozym bacterial and fungal pathogens like
apple scab or fireblight
Chitinases bacterial and fungal pathogens like
apple scab or fireblight
Bamase bacterial and fungal pathogens like
apple scab or fireblight
Glucanases bacterial and fungal pathogens like
apple scab or fireblight
double stranded ribonuclease viruses
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or viruses
Nucleoprotein
Pseudoubiquitin viruses
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, iepidoptera, aphids, mites
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites
Peroxidase lepidoptera, aphids, mites
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites
aminopeptidase inhibitor
Lectines lepidoptera, aphids, mites
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

CPTI
ribosome inactivating protein lepidoptera, aphids, mites
stilbene synthase lepidoptera, aphids, diseases, mites
HMG-CoA reductase lepidoptera, aphids, mites
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table Al 3: Crop Melons

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transf erase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitriiase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or suitosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens like
oxidase antisense phytophtora
Metallothionein bacterial or fungal pathogens like
phytophtora
Ribonuclease bacterial or fungal pathogens like
phytophtora
Antifungal polypeptide AIyAFP bacterial or fungal pathogens like
phytophtora

oxalate oxidase bacterial or fungal pathogens like
phytophtora
glucose oxidase bacterial or fungal pathogens like
phytophtora
pyrrolnitrin synthesis genes bacterial or fungal pathogens like
phytophtora
serine/threonine kinases bacterial or fungal pathogens like
phytophtora
Cecropin B bacterial or fungal pathogens like
phytophtora
Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens like
phytophtora
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens like
phytophtora
Osmotin bacterial or fungal pathogens like
phytophtora


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Alpha Hordothionin bacterial or fungal pathogens like
phytophtora
Systemin bacterial or fungal pathogens like
phytophtora
Polygalacturonase inhibitors bacterial or fungal pathogens like
phytophtora
Prf regulatory gene bacterial or fungal pathogens like
phytophtora
phytoalexins bacterial or fungal pathogens like
phytophtora
B-1,3-glucanase antisense bacterial or fungal pathogens like
phytophtora
receptor kinase bacterial or fungal pathogens like
phytophtora
Hypersensitive response eliciting bacterial or fungal pathogens like
polypeptide phytophtora
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens like
phytophtora
Lysozym bacterial or fungal pathogens like
phytophtora

Chitinases bacterial or fungal pathogens like
phytophtora
Bamase bacterial or fungal pathogens like
phytophtora
Glucanases bacterial or fungal pathogens like
phytophtora
double stranded ribonuclease viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
Coat proteins viruses as CMV,, PRSV, WMV2, SMV,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

ZYMV
17kDa or 60 kDa protein viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
Nuclear inclusion proteins eg. a or b or viruses as CMV,, PRSV, WMV2, SMV,
Nucleoprotein ZYMV
Pseudoubiquitin viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
Replicase viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, whitefly
Peroxidase lepidoptera, aphids, mites, whitefly
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, whitefly
aminopeptidase inhibitor
Lectines lepidoptera, aphids, mites, whitefly
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, whitefly
CPTI, virgiferin
ribosome inactivating protein lepidoptera, aphids, mites, whitefly
stilbene synthase lepidoptera, aphids, mites, whitefly
HMG-CoA reductase lepidoptera, aphids, mites, whitefly
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A14: Crop Banana

Effected target or expressed principle(s) ( Crop phenotype / Tolerance to


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pynmidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cydohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitnles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens
glucose oxidase bacterial or fungal pathogens


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

pyrrolnitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens
Chitinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuclease viruses as Banana bunchy top virus
(BBTV)
Coat proteins viruses as Banana bunchy top virus
(BBTV)
17kDa or 60 kDa protein viruses as Banana bunchy top virus
(BBTV)
Nuclear inclusion proteins eg. a or b or viruses as Banana bunchy top virus
Nucleoprotein (BBTV)
Pseudoubiquitin viruses as Banana bunchy top virus
(BBTV)


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Replicase viruses as Banana bunchy top virus
(BBTV)
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes
Peroxidase lepidoptera, aphids, mites, nematodes
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes
aminopeptidase inhibitor
Lectines lepidoptera, aphids, mites, nematodes
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes
CPTI, virgiferin
ribosome inactivating protein lepidoptera, aphids, mites, nematodes
stilbene synthase lepidoptera, aphids, mites, nematodes
HMG-CoA reductase lepidoptera, aphids, mites, nematodes
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table Al 5: Crop Cotton

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) isoxachlortol, Triones such as


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

mesotrione or suicotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens
glucose oxidase bacterial or fungal pathogens
pyrrolnitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens
Chitinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuciease viruses as wound tumor virus (WTV)
Coat proteins viruses as wound tumor virus (WTV)
17kDa or 60 kDa protein viruses as wound tumor virus (WTV)
Nuclear inclusion proteins eg. a or b or viruses as wound tumor virus (WTV)
Nucleoprotein
Pseudoubiquitin viruses as wound tumor virus (WTV)
Replicase viruses as wound tumor virus (WTV)
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefly
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes,
whitefly
Peroxidase lepidoptera, aphids, mites, nematodes,
whitefly
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly
Lectines lepidoptera, aphids, mites, nematodes,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

whitefly
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whtfefly
ribosome inactivating protein lepidoptera, aphids, mites, nematodes,
whitefly
stilbene synthase lepidoptera, aphids, mites, nematodes,
whitefly
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A16: Crop Sugarcane

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) lsoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sultonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens
glucose oxidase bacterial or fungal pathogens
pyrrolnitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens eg
clavibacter
Chitinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuclease viruses as SCMV, SrMV
Coat proteins viruses as SCMV, SrMV
17kDa or 60 kDa protein viruses as SCMV, SrMV
Nuclear inclusion proteins eg. a or b or viruses as SCMV, SrMV
Nucleoprotein
Pseudoubiquitin viruses as SCMV, SrMV
Replicase viruses as SCMV, SrMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefly, beetles eg mexican rice
borer
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
Peroxidase lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly, beetles eg mexican rice borer
Lectines lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whitefly, beetles eg mexican rice borer


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

ribosome inactivating protein lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
stitbene synthase lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
Cyst nematode hatching stimulus cyst nematodes
Barnase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A17: Crop Sunflower

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazotopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine syrithetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitritase 3,5-dihalo-4-hydroxy-benzonitriles such


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopytate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens
oxidase antisense
Metaliothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens eg
scierotinia
glucose oxidase bacterial or fungal pathogens
pyrrolnitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 ON Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens
Chitinases bacterial or fungal pathogens
Barnase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuclease viruses as CMV, TMV
Coat proteins viruses as CMV, TMV
17kDa or 60 kDa protein viruses as CMV, TMV
Nuclear inclusion proteins eg. a or b or viruses as CMV, TMV
Nucleoprotein
Pseudoubiquitin viruses as CMV, TMV
Replicase viruses as CMV, TMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefly, beetles
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes,
whitefly, beetles
Peroxidase lepidoptera, aphids, mites, nematodes,
whitefly, beetles

Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly, beetles
Lectines lepidoptera, aphids, mites, nematodes,
whitefly, beetles
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whitefly, beetles
ribosome inactivating protein lepidoptera, aphids, mites, nematodes,
whitefly, beetles
stilbene synthase lepidoptera, aphids, mites, nematodes,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

whitefly, beetles
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly, beetles
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A18: Crop Sugarbeet, Beet root

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transf erase Phosphinothricin
O-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens eg
scierotinia
glucose oxidase bacterial or fungal pathogens
pyrrolnitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
AX + WIN proteins bacterial or fungal pathogens like
Cercospora beticola
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens
Chitinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuclease viruses as BNYVV
Coat proteins viruses as BNYVV
17kDa or 60 kDa protein viruses as BNYVV
Nuclear inclusion proteins eg. a or b or viruses as BNYVV
Nucleoprotein
Pseudoubiquitin viruses as BNYVV
Replicase viruses as BNYVV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefly, beetles, rootflies
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies
Peroxidase lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly, beetles, rootflies
Lectines lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whitefly, beetles, rootflies
ribosome inactivating protein lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies
stilbene synthase lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
Beet cyst nematode resistance locus cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

The abovementioned animal pests which can be controlled by the method
according to the
invention (A) include, for example, insects, representatives of the order
acarina and
representatives of the class nematoda; especially

from the order Lepidoptera Acleris spp., Adoxophyes spp., especially
Adoxophyes
reticulana; Aegeria.spp., Agrotis spp., especially Agrotis spinifera; Alabama
argillaceae,
Amylois spp., Anticarsia gemmatalis, Archips spp., Argyrotaenia spp.,
Autographa spp.,
Busseola fusca, Cadre, cautella, Carposina nipponensis, Chilo spp.,
Choristoneura spp.,
Ciysia ambiguella, Cnaphalocrocis spp., Cnephasia spp., Cochylis spp.,
Coleophora spp.,
Crocidolomia binotalis, Cryptophlebia leucotreta, Cydia spp., especially Cydia
pomonella;
Diatraea spp., Diparopsis castanea, Earias spp., Ephestia spp., especially E.
Khuniella;
Eucosma spp., Eupoecilia ambiguella, Euproctis spp., Euxoa spp., Grapholita
spp., Hedya
nubiferana, Heliothis spp., especially H. virescens and H. zea; Hellula
undalis, Hyphantria
cunea, Keiferia lycopersicella, Leucoptera scitella, Lithocollethis spp.,
Lobesiaspp.,
Lymantria spp., Lyonetia spp., Malacosoma spp., Mamestra brassicae, Manduca
sexta,
Operophtera spp., Ostrinia nubilalis, Pammene spp., Pandemis spp., Panolis
flammea,
Pectinophora spp., Phthorimaea operculella, Pieris rapae, Pieris spp.,
Plutella xylostella,
Prays spp., Scirpophaga spp., Sesamia spp., Sparganothis spp.,
Spodopteralittoralis,
Synanthedon spp., Thaumetopoea spp., Tortrix spp., Trichoplusia ni and
Yponomeuta spp.;
from the order Coleoptera, for example Agriotes spp., Anthonomus spp.,
Atomaria linearis,
Chaetocnema tibialis, Cosmopolites spp., Curculio spp., Dermestes spp.,
Diabrotica spp.,
Epilachna spp., Eremnus spp., Leptinotarsa decemlineata, Lissorhoptrus spp.,
Melolontha
spp., Oryzaephilus spp., Otiorhynchus spp., Phlyctinus spp., Popillia spp.,
Psylliodes spp.,
Rhizopertha spp., Scarabeidae, Sitophilus spp., Sitotroga spp., Tenebrio spp.,
Tribolium
spp. and Trogoderma spp.;


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from the order Orthoptera, for example Blatta spp., Blattella spp.,
Gryllotalpa spp.,
Leucophaea maderae, Locusta spp., Periplaneta spp. and Schistocerca spp.;

from the order Isoptera, for example Reticulitermes spp.;
from the order Psocoptera, for example Liposcelis spp.;

from the order Anoplura, for example Haematopinus spp., Linognathus spp.,
Pediculus
spp., Pemphigus spp. and Phylloxera spp.;

from the order Mallophaga, for example Damalinea spp. and Trichodectes spp.;
from the order Thysanoptera, for example Frankliniella spp., Hercinothrips
spp.,
Taeniothrips spp., Thrips palmi, Thrips tabaci and Scirtothrips aurantii;

from the order Heteroptera, for example Cimex spp., Distantiella theobroma,
Dysdercus
spp., Euchistus spp. Eurygaster spp. Leptocorisa spp., Nezara spp., Piesma
spp., Rhodnius
spp., Sahlbergella singularis, Scotinophara spp. and Triatoma spp.;

from the order Homoptera, for example Aleurothrixus floccosus, Aleyrodes
brassicae,
Aonidielia aurantii, Aphididae, Aphiscraccivora, A. fabae, A. gosypii;
Aspidiotus spp.,
Bemisia tabaci, Ceroplaster spp., Chrysomphalus aonidium, Chrysomphalus
dictyospermi,
Coccus hesperidum, Empoasca spp., Eriosoma lanigerum, Erythroneura spp.,
Gascardia
spp., Laodelphax spp., Lecanium corni, Lepidosaphes spp., Macrosiphus spp.,
Myzus spp.,
especially M.persicae; Nephotettix spp., especially N. cincticeps; Nilaparvata
spp.,
especially N. lugens; Paratoria spp., Pemphigus spp., Planococcus spp.,
Pseudaulacaspis
spp., Pseudococcus spp., especially P. Fragilis, P. citriculus and P.
comstocki; Psylla spp.,
especially P. pyri; Pulvinaria aethiopica, Quadraspidiotus spp., Rhopalosiphum
spp.,
Saissetia spp., Scaphoideus spp., Schizaphis spp., Sitobion spp., Trialeurodes
vaporariorum, Trioza erytreae and Unaspis citri;

from the order Hymenoptera, for example Acromyrmex, Atta spp., Cephus spp.,
Diprion
spp., Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium
pharaonis, Neodiprion spp., Solenopsis spp. and Vespa spp.;

from the order Diptera, for example Aedes spp., Antherigona soccata, Bibio
hortulanus,
Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp.,
Cuterebra spp.,
Dacus spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Glossina
spp.,
Hypoderma spp., Hyppobosca spp., Linomyza spp., Lucilia spp., Melanagromyza
spp.,
Musca spp., Oestrus spp., Orseolia spp., Oscinella frit, Pegomyia hyoscyami,
Phorbia spp.,


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Rhagoletis pomonella, Sciara spp., Stomoxys spp., Tabanus spp., Tannia spp.
and Tipula
sPP=;

from the order Siphonaptera, for example Ceratophyllus spp. and Xenopsylla
cheopis;
from the order Thysanura, for example Lepisma saccharins and

from the order Acarina, for example Acarus siro, Aceria sheldoni; Aculus spp.,
especially A.
schlechtendali; Amblyomma spp., Argas spp., Boophilus spp., Brevipalpus spp.,
especially
B. califomicus and B. phoenicis; Bryobia.praetiosa, Calipitrimerus spp.,
Chorioptes spp.,
Dermanyssus gallinae, Eotetranychus spp., especially E.carpini and E.
orientalis; Eriophyes
spp., especially E. vitis; Hyalomma spp., Ixodes spp., Olygonychus pratensis,
Omithodoros
spp., Panonychus spp., especially P. utmi and P. citri; Phyllocoptruta spp.,
especially P.
oleivora; Polyphagotarsonemus spp., especially P. latus; Psoroptes spp.,
Rhipicephalus
spp., Rhizoglyphus spp., Sarcoptes spp., Tarsonemus spp. and Tetranychus spp.,
in
particular T. urticae, T. cinnabarinus and T. Kanzawai;

representatives of the class Nematoda;

(1) nematodes selected from the group consisting of root knot nematodes, cyst-
forming
nematodes, stem eelworms and foliar nematodes;

(2) nematodes selected from the group consisting of Anguina spp.;
Aphelenchoides spp.;
Ditylenchus spp.; Globodera spp., for example Globodera rostochiensis;
Heterodera spp.,
for example Heterodera avenae, Heterodera glycines, Heterodera schachtii or
Heterodera
trifolii; Longidorus spp.; Meloidogyne spp., for example Meloidogyne incognita
or
Meloidogyne javanica; Pratylenchus, for example Pratylenchus neglectans or
Pratylenchus
penetrans; Radopholus spp., for example Radopholus similis; Trichodorus spp.;
Tylenchulus, for example Tylenchulus semipenetrans; and Xiphinema spp.; or

(3) nematodes selected from the group consisting of Heterodera spp., for
example
Heterodera glycines; and Meloidogyne spp., for example Meloidogyne incognita.

The method according to the invention (A) allows pests of the abovementioned
type to be
controlled, i.e. contained or destroyed, which occur, in particular, on
transgenic plants,
mainly useful plants and ornamentals in agriculture, in horticulture and in
forests, or on
parts, such as fruits, flowers, foliage, stalks, tubers or roots, of such
plants, the protection
against these pests in some cases even extending to plant parts which form at
a later point
in time.


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The method according to the invention (A) can be employed advantageously for
controlling
pests in rice, cereals such as maize or sorghum; in fruit, for example stone
fruit, pome fruit
and soft fruit such as apples, pears, plums, peaches, almonds, cherries or
berries, for
example strawberries, raspberries and blackberries; in legumes such as beans,
lentils, peas
or soya beans; in oil crops such as oilseed rape, mustard, poppies, olives,
sunflowers,
coconuts, castor-oil plants, cacao or peanuts; in the marrow family such as
pumpkins,
cucumbers or melons; in fibre plants such as cotton, flax, hemp or jute; in
citrus fruit such as
oranges, lemons, grapefruit or tangerines; in vegetables such as spinach,
lettuce,
asparagus, cabbage species, carrots, onions, tomatoes, potatoes, beet or
capsicum; in the
laurel family such as avocado, Cinnamonium or camphor; or in tobacco, nuts,
coffee, egg
plants, sugar cane, tea, pepper, grapevines, hops, the banana family, latex
plants or
ornamentals, mainly in maize, rice, cereals, soya beans, tomatoes, cotton,
potatoes, sugar
beet, rice and mustard; in particular in cotton, rice, soya beans, potatoes
and maize.

It has emerged that the method according to the invention (A) is valuable
preventatively
and/or curatively in the field of pest control even at low use concentrations
of the pesticidal
composition and that a very favourable biocidal spectrum is achieved thereby.
Combined
with a favourable compatibility of the composition employed with warm-blooded
species,
fish and plants, the method according to the invention can be employed against
all or
individual developmental stages of normally-sensitive, but also of normally-
resistant, animal
pests such as insects and representatives of the order Acarina, depending on
the species
of the transgenic crop plant to be protected from attack by pests. The
insecticidal and/or
acaricidal effect of the method according to the invention may become apparent
directly, i.e.
in a destruction of the pests which occurs immediately or only after some time
has elapsed,
for example, during ecdysis, or indirectly, for example as a reduced
oviposition and/or
hatching rate, the good action corresponding to a destruction rate (mortality)
of at least 40
to 50%.

Depending on the intended aims and the prevailing circumstances, the
pesticides within the
scope of invention (A), which are known per se, are emulsifiable concentrates,
suspension
concentrates, directly sprayable or dilutable solutions, spreadable pastes,
dilute emulsions,
wettable powders, soluble powders, dispersible powders, wettable powders,
dusts, granules
or encapsulations in polymeric substances which comprise a macrolide compound.


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The active ingredients are employed in these compositions together with at
least one of the
auxiliaries conventionally used in art of formulation, such as extenders, for
example
solvents or solid carriers, or such as surface-active compounds (surfactants).

Formulation auxiliaries which are used are, for example, solid carriers,
solvents, stabilizers,
"slow release" auxiliaries, colourants and, if appropriate, surface-active
substances
(surfactants). Suitable carriers and auxiliaries are all those substances
which are con-
ventionally used for crop protection products. Suitable auxiliaries such as
solvents, solid
carriers, surface-active compounds, non-ionic surfactants, cationic
surfactants, anionic
surfactants and other auxiliaries in the compositions employed according to
the invention
are, for example, those which have been described in EP-A-736 252.

These compositions for controlling pests can be formulated, for example, as
wettable
powders, dusts, granules, solutions, emulsifiable concentrates, emulsions,
suspension
concentrates or aerosols. For example, the compositions are of the type
described in EP-
A-736 252.

The action of the compositions within the scope of invention (A) which
comprise a macrolide
compound can be extended substantially and adapted to prevailing circumstances
by
adding other insecticidally, acaricidally and/or fungicidally active
ingredients. Suitable
examples of added active ingredients are representatives of the following
classes of active
ingredients: organophosphorous compounds, nitrophenols and derivatives,
formamidines,
ureas, carbamates, pyrethroids, chlorinated hydrocarbons; especially preferred
components
in mixtures are, for example, thiamethoxam, pymetrozine, fenoxycarb,
imidacloprid, Ti-435,
fipronil, pyriproxyfen, emamectin, diazinon or diafenthiuron.

As a rule, the compositions within the scope of invention (A) comprise 0.1 to
99%, in
particular 0.1 to 95 %, of a macrolide compound and 1 to 99.9 %, in particular
5 to 99.9 %,
of - at least - one solid or liquid auxiliary, it being possible, as a rule,
for 0 to 25 %, in parti-
cular 0.1 to 20 %, of the compositions to be surfactants (% in each case
meaning per cent
by weight). While concentrated compositions are more preferred as commercial
products,
the end user will, as a rule, use dilute compositions which have considerably
lower
concentrations of active ingredient.

The compositions according to the invention (A) may also comprise other solid
or liquid
auxiliaries, such as stabilisers, for example epoxidized or unepoxidized
vegetable oils (for
example epoxidized coconut oil, rapeseed oil or soya bean oil), antifoams, for
example


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silicone oil, preservatives, viscosity regulators, binders and/or tackifiers,
and also fertilizers
or other active ingredients for achieving specific effects, for example,
bactericides,
fungicides, nematicides, molluscicides or herbicides.

The compositions according to the invention (A) are produced in a known
manner, for
example prior to mixing with the auxiliary/auxiliaries by grinding, screening
and/or
compressing the active ingredient, for example to give a particular particle
size, and by
intimately mixing and/or grinding the active ingredient with the
auxiliary/auxiliaries.

The method according to the invention for controlling pests of the
abovementioned type is
carried out in a manner known per se to those skilled in the art, depending on
the intended
aims and prevailing circumstances, that is to say by spraying, wetting,
atomizing, dusting,
brushing on, seed dressing, scattering or pouring of the composition. Typical
use concen-
trations are between 0.1 and 1000 ppm, preferably between 0.1 and 500 ppm of
active
ingredient. The application rate may vary within wide ranges and depends on
the soil
constitution, the type of application (foliar application; seed dressing;
application in the seed
furrow), the transgenic crop plant, the pest to be controlled, the climatic
circumstances
prevailing in each case, and other factors determined by the type of
application, timing of
application and target crop. The application rates per hectare are generally 1
to 2000 g of
macrolide compound per hectare, in particular 10 to 1000 g/ha, preferably 10=
to 500 g/ha,
especially preferably 10 to 200 g/ha.

A preferred type of application in the field of crop protection within the
scope of invention
(A) is application to the foliage of the plants (foliar application), it being
possible to adapt
frequency and rate of application to the risk of infestation with the pest in
question.
However, the active ingredient may also enter into the plants via the root
system (systemic
action), by drenching the site of the plants with a liquid composition or by
incorporating the
active ingredient in solid form into the site of the plants, for example into
the soil, for
example in the form of granules (soil application). In the case of paddy rice
crops, such
granules may be metered into the flooded paddy field.

The compositions according to invention (A) are also suitable for protecting
propagation
material of transgenic plants, for example seed, such as fruits, tubers or
kernels, or plant
cuttings, from animal pests, in particular insects and representatives of the
order Acarina.
The propagation material can be treated with the composition prior to
application, for
example, seed being dressed prior to sowing. The active ingredient may also be
applied to


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seed kernels (coating), either by soaking the kernels in a liquid composition
or by coating
them with a solid composition. The composition may also be applied to the site
of
application when applying the propagation material, for example into the seed
furrow during
sowing. These treatment methods for plant propagation material and the plant
propagation
material treated thus are a further subject of the invention.

Examples of formulations of macrolide compounds which can be used in the
method
according to the invention (A), for instance solutions, granules, dusts,
sprayable powders,
emulsion concentrates, coated granules and suspension concentrates, are of the
type as
has been described in, for example, EP-A-580 553, Examples F1 to F10.

Table B

The following abreviations are used in the table:
Active Principle of transgenic plant: AP
Photorhabdus luminescens: PL
Xenorhabdus nematophilus: XN
Proteinase Inhibitors: Plnh.
Plant lectins Plec
Agglutinins: Aggi.
3-Hydroxysteroid oxidase: HO
Cholesteroloxidase: CO
Chitinase: CH
Glucanase: GL
Stilbensynthase SS
Table 0:

AP Control of AP Control of
B.1 CrylA(a) Adoxophyes spp. B.5 CrylA(a) Chilo spp.
B.2 CrylA(a) Agrotis spp. B.6 CrylA(a) Clysia ambiguella
B.3 CrylA(a) Alabama B.7 CrylA(a) Crocidolomia
argillaceae binotalis
B.4 CrylA(a) Anticarsia B.8 CrylA(a) Cydia spp.
gemmatalis B.9 CrylA(a) Diparopsis


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AP Control of AP Control of

castanea B.38 CryIA(a) Aleyrodes spp.
B.10 CrylA(a) Earias spp. B.39 CrylA(a) Aonidiella spp.
B. 11 CrylA(a) Ephestia spp. B.40 CrylA(a) Aphididae spp.
B.12 CrylA(a) Heliothis spp. B.41 CrylA(a) Aphis spp.
B. 13 CrylA(a) Hellula undalis B.42 CrylA(a) Bemisia tabaci
B. 14 CryIA(a) Keiferia B.43 CrylA(a) Empoasca spp.
lycopersicella B.44 CrylA(a) Mycus spp.
B. 15 CrylA(a) Leucoptera scitella B.45 CrylA(a) Nephotettix spp.
B. 16 CrylA(a) Lithocollethis spp. B.46 CrylA(a) Nitaparvata spp.
B. 17 CrylA(a) Lobesia botrana B.47 CrylA(a) Pseudococcus spp.
B.18 CrylA(a) Ostrinia nubilalis B.48 CrylA(a) Psylla spp.
B. 19 CrylA(a) Pandemis spp. B.49 CrylA(a) Quadraspidiotus
B.20 CrylA(a) Pectinophora spp.
gossyp. B.50 CrylA(a) Schizaphis spp.
B.21 CrylA(a) Phyliocnistis citrella B.51 CrylA(a) Trialeurodes spp.
B.22 CrylA(a) Pieris spp. B.52 CrylA(a) Lyriomyza spp.
B.23 CrylA(a) Plutella xylostella B.53 CrylA(a) Oscinella spp.
B.24 CrylA(a) Scirpophaga spp. B.54 CrylA(a) Phorbia spp.
B.25 CrylA(a) Sesamia spp. B.55 CrylA(a) Frankliniella spp.
B.26 CrylA(a) Sparganothis spp. B.56 CrylA(a) Thrips spp.
B.27 CrylA(a) Spodoptera spp. B.57 CrylA(a) Scirtothrips aurantii
B.28 CrylA(a) Tortrix spp. B.58 CrylA(a) Aceria spp.
B.29 CrylA(a) Trichoplusia ni B.59 CrylA(a) Aculus spp.
B.30 CrylA(a) Agriotes spp. B.60 CrylA(a) Brevipalpus spp.
B.31 CrylA(a) Anthonomus B.61 CrylA(a) Panonychus spp.
grandis B.62 CrylA(a) Phyllocoptruta spp.
B.32 CrylA(a) Curculio spp. B.63 CryIA(a) Tetranychus spp.
B.33 CrylA(a) Diabrotica balteata B.64 CrylA(a) Heterodera spp.
B.34 CrylA(a) Leptinotarsa spp. B.65 CrylA(a) Meloidogyne spp.
B.35 CrylA(a) Lissorhoptrus spp. B.66 CrylA(b) Adoxophyes spp.
B.36 CrylA(a) Otiorhynchus spp. B.67 CrylA(b) Agrotis spp.
B.37 CrylA(a) Aleurothrixus spp. B.68 CrylA(b) Alabama


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AP Control of AP Control of

argillaceae B.95 CrylA(b) Agriotes spp.
B.69 CrylA(b) Anticarsia B.96 CrylA(b) Anthonomus
gemmatalis grandis
B.70 CrylA(b) Chilo spp. B.97 CrylA(b) Curculio spp.
B.71 CrylA(b) Clysia ambiguella B.98 CrylA(b) Diabrotica balteata
B.72 CryIA(b) Crocidolomia B.99 CrylA(b) Leptinotarsa spp.
binotalis B.100 CrylA(b) Lissorhoptrus spp.
B.73 CrylA(b) Cydia spp. B.101 CrylA(b) Otiorhynchus spp.
B.74 CrylA(b) Diparopsis B.102 CryIA(b) Aleurothrixus spp.
castanea B. 103 CrylA(b) Aleyrodes spp.
B.75 CrylA(b) Earias spp. B.104 CrylA(b) Aonidiella spp.
B.76 CrylA(b) Ephestia spp. B.105 CrylA(b) Aphididae spp.
B.77 CrylA(b) Heliothis spp. B.106 CrylA(b) Aphis spp.
B.78 CrylA(b) Hellula undalis B.107 CrylA(b) Bemisia tabaci
B.79 CrylA(b) Keiferia B.108 CrylA(b) Empoasca spp.
iycopersicella B.109 CrylA(b) Mycus spp.
B.80 CrylA(b) Leucoptera scitella B.110 CrylA(b) Nephotettix spp.
B.81 CrylA(b) Lithocollethis spp. B.111 CrylA(b) Nilaparvata spp.
B.82 CrylA(b) Lobesia botrana B.112 CrylA(b) Pseudococcus spp.
B.83 CrylA(b) Ostrinia nubilalis B.113 CrylA(b) Psylla spp.
B.84 CrylA(b) Pandemis spp. B.114 CrylA(b) Quadraspidiotus
B.85 CrylA(b) Pectinophora spp.
gossyp. B.115 CrylA(b) Schizaphis spp.
B.86 CrylA(b) Phyllocnistis citrella B.116 CrylA(b) Trialeurodes spp.
B.87 CrylA(b) Pieris spp. B.117 CrylA(b) Lyriomyza spp.
B.88 CrylA(b) Plutella xylostella B.118 CrylA(b) Oscinella spp.
B.89 CrylA(b) Scirpophaga spp. B.119 CryIA(b) Phorbia spp.
B.90 CrylA(b) Sesamia spp. B.120 CrylA(b) Frankliniella spp.
B.91 CryIA(b) Sparganothis spp. B.121 CrylA(b) Thrips spp.
B.92 CrylA(b) Spodoptera spp. B.122 CrylA(b) Scirtothrips aurantii
B.93 CrylA(b) Tortrix spp. B.123 CrylA(b) Aceria spp.
B.94 CrylA(b) Trichoplusia ni B.124 CrylA(b) Aculus spp.


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AP Control of AP Control of

B.125 CrylA(b) Brevipalpus spp. B. 151 CrylA(c) Phyllocnistis citrella
B.126 CrylA(b) Panonychus spp. B.152 CrylA(c) Pieris spp.
B.127 CrylA(b) Phyllocoptruta spp. B.153 CrylA(c) Plutella xylostella
B.128 CrylA(b) Tetranychus spp. B.154 CrylA(c) Scirpophaga spp.
B.129 CrylA(b) Heterodera spp. B.155 CrylA(c) Sesamia spp.
B.130 CrylA(b) Meloidogyne spp. B.156 CrylA(c) Sparganothis spp.
B.131 CrylA(c) Adoxophyes spp. B.157 CrylA(c) Spodoptera spp.
B.132 CryIA(c) Agrotis spp. B.158 CrylA(c) Tortrix spp.
B.133 CrylA(c) Alabama B.159 CrylA(c) Trichoplusia ni
argillaceae B.160 CrylA(c) Agriotes spp.
B.134 CrylA(c) Anticarsia B.161 CrylA(c) Anthonomus
gemmatalis grandis
B.135 CrylA(c) Chilo spp. B.162 CrylA(c) Curculio spp.
B.136 CrylA(c) Clysia ambiguella B.163 CryIA(c) Diabrotica balteata
B.137 CrylA(c) Crocidolomia B.164 CrylA(c) Leptinotarsa spp.
binotalis B.165 CrylA(c) Lissorhoptrus spp.
B.138 CrylA(c) Cydia spp. B.166 CrylA(c) Otiorhynchus spp.
B.139 CrylA(c) Diparopsis B.167 CrylA(c) Aleurothrixus spp.
castanea B.168 CrylA(c) Aleyrodes spp.
B.140 CrylA(c) Earias spp. B.169 CrylA(c) Aonidiella spp.
B.141 CrylA(c) Ephestia spp. B.170 CrylA(c) Aphididae spp.
B.142 CrylA(c) Heliothis spp. B.171 CrylA(c) Aphis spp.
B.143 CrylA(c) Hellula undalis B.172 CrylA(c) Bemisia tabaci
B. 144 CrylA(c) Keiferia B.173 CrylA(c) Empoasca spp.
lycopersicella B.174 CryIA(c) Mycus spp.
B.145 CrylA(c) Leucoptera scitella B.175 CrylA(c) Nephotettix spp.
B. 146 CrylA(c) Lithocollethis spp. B.176 CrylA(c) Nilaparvata spp.
B.147 CrylA(c) Lobesia botrana B.177 CrylA(c) Pseudococcus spp.
B. 148 CrylA(c) Ostrinia nubilalis B.178 CrylA(c) Psylla spp.
B.149 CrylA(c) Pandemis spp. B.179 CrylA(c) Quadraspidiotus
B.150 CrylA(c) Pectinophora spp.
gossypiella. B.180 CrylA(c) Schizaphis spp.


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AP Control of AP Control of

B.181 CrylA(c) Trialeurodes spp. B.209 CryllA Keiferia
B.182 CrylA(c) Lyriomyza spp. lycopersicella
B.183 CrylA(c) Oscinella spp. B.210 CryllA Leucoptera scitella
B.184 CrylA(c) Phorbia spp. B.211 CryllA Lithocollethis spp.
B.185 CrylA(c) Frankliniella spp. B.212 CryllA Lobesia botrana
B.186 CrylA(c) Thrips spp. B.213 CryllA Ostrinia nubilalis
B.187 CrylA(c) Scirtothrips aurantii B.214 CryllA Pandemis spp.
B.188 CrylA(c) Aceria spp. B.215 CryllA Pectinophora
B.189 CrylA(c) Aculus spp. gossyp.
B.190 CrylA(c) Brevipalpus spp. B.216 CryllA Phyllocnistis citrella
B.191 CrylA(c) Panonychus spp. B.217 CryllA Pieris spp.
B.192 CrylA(c) Phyllocoptruta spp. B.218 CryllA Plutella xylostella
B.193 CrylA(c) Tetranychus spp. B.219 CryllA Scirpophaga spp.
B.194 CrylA(c) Heterodera spp. B.220 CryllA Sesamia spp.
B.195 CrylA(c) Meloidogyne spp. B.221 CryllA Sparganothis spp.
B.196 CryIlA Adoxophyes spp. B.222 CrylIA Spodoptera spp.
B.197 CrylIA Agrotis spp. B.223 CryllA Tortrix spp.
B.198 CryllA Alabama B.224 CryllA Trichoplusia ni
argillaceae B.225 CryllA Agriotes spp.
B.199 CryllA Anticarsia B.226 CryllA Anthonomus
gemmatalis grandis
B.200 CryllA Chilo spp. B.227 CryIlA Curculio spp.
B.201 CryllA Clysia ambiguella B.228 CryllA Diabrotica balteata
B.202 CryllA Crocidolomia B.229 CryllA Leptinotarsa spp.
binotalis B.230 CryllA Lissorhoptrus spp.
B.203 CryllA Cydia spp. B.231 CryllA Otiorhynchus spp.
B.204 CryllA Diparopsis B.232 CryllA Aleurothrixus spp.
castanea B.233 CryllA Aleyrodes spp.
B.205 CryllA Earias spp. B.234 CryllA Aonidiella spp.
B.206 CryllA Ephestia spp. B.235 CryllA Aphididae spp.
B.207 CryllA Heliothis spp. B.236 CryllA Aphis spp.
B.208 CryllA Hellula undalis B.237 CryllA Bemisia tabaci


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AP Control of AP Control of

B.238 CryllA Empoasca spp. B.267 CryillA Crocidolomia
B.239 CryllA Mycus spp. binotalis
B.240 CryllA Nephotettix spp. B.268 CrylitA Cydia spp.
B.241 CryllA Nilaparvata spp. B.269 CryllIA Diparopsis
B.242 CryllA Pseudococcus spp. castanea
B.243 CryllA Psylla spp. B.270 CryllIA Earias spp.
B.244 CryllA Quadraspidiotus B.271 CryIIIA Ephestia spp.
spp. B.272 CryllIA Heliothis spp.
B.245 CryIlA Schizaphis spp. B.273 CryllIA Hellula undalis
B.246 CryllA Trialeurodes spp. B.274 CryllIA Keiferia
B.247 CryIlA Lyriomyza spp. lycopersicella
B.248 CryIlA Oscinella spp. B.275 CryllIA Leucoptera scitella
B.249 CryllA Phorbia spp. B.276 CryllIA Lithocollethis spp.
B.250 CryllA Frankliniella spp. B.277 CryillA Lobesia botrana
B.251 CryllA Thrips spp. B.278 CryllIA Ostrinia nubilalis
B.252 CryIlA Scirtothrips aurantii B.279 CryllIA Pandemis spp.
B.253 CryIlA Aceria spp. B.280 CryllIA Pectinophora
B.254 CryllA Aculus spp. gossyp.
B.255 CryllA Brevipalpus spp. B.281 CryllIA Phyllocnistis citrella
B.256 CryllA Panonychus spp. B.282 CryllIA Pieris spp.
B.257 CryllA Phyllocoptruta spp. B.283 CryllIA Plutella xylostella
B.258 CryllA Tetranychus spp. B.284 CryllIA Scirpophaga spp.
B.259 CryllA Heterodera spp. B.285 CryllIA Sesamia spp.
B.260 CryllA Meloidogyne spp. B.286 CrylliA Sparganothis spp.
B.261 CrylllA Adoxophyes spp. B.287 CryillA Spodoptera spp.
B.262 CryllIA Agrotis spp. B.288 CrylliA Tortrix spp.
B.263 CryllIA Alabama B.289 CryllIA Trichoplusia ni
argillaceae B.290 CryllIA Agriotes spp.
B.264 CryIIIA Anticarsia B.291 CryllIA Anthonomus
gemmatalis grandis
B.265 CryllIA Chilo spp. B.292 CryllIA Curculio spp.
B.266 CryllIA Clysia ambiguella B.293 CryllIA Diabrotica balteata


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AP Control of AP Control of

B.294 CryIIIA Leptinotarsa spp. B.325 CryllIA Meloidogyne spp.
B.295 CryllIA Lissorhoptrus spp. B.326 CrylllB2 Adoxophyes spp.
B.296 CryllIA Otiorhynchus spp. B.327 CryIIIB2 Agrotis spp.
B.297 CryIIIA Aleurothrixus spp. B.328 CryIIIB2 Alabama
B.298 CryllIA Aleyrodes spp. argillaceae
B.299 CryllIA Aonidiella spp. B.329 CryIIIB2 Anticarsia
B.300 CryllIA Aphididae spp. gemmatalis
B.301 CryllIA Aphis spp. B.330 CryIIIB2 Chilo spp.
B.302 CryllIA Bemisia,tabaci B.331 CrylllB2 Clysia ambiguella
B.303 CryllIA Empoasca spp. B.332 CryIIIB2 Crocidolomia
B.304 CryllIA Mycus spp. binotalis
B.305 CryllIA Nephotettix spp. B.333 CryIIIB2 Cydia spp.
B.306 CryillA Nilaparvata spp. B.334 CryIIIB2 Diparopsis
B.307 CryllIA Pseudococcus spp. castanea
B.308 CryllIA Psylla spp. B.335 CryIIIB2 Earias spp.
B.309 CryllIA Quadraspidiotus B.336 CryIIIB2 Ephestia spp.
spp. B.337 CryIIIB2 Heliothis spp.
B.310 CryllIA Schizaphis spp. B.338 CryIIIB2 Hellula undalis
B.311 CryllIA Trialeurodes spp. B.339 CrylIIB2 Keiferia
B.312 CryllIA Lyriomyza spp. lycopersicella
B.313 CryllIA Oscinella spp. B.340 CrylllB2 Leucoptera scitella
B.314 CryIIIA Phorbia spp. B.341 CryIIIB2 Lithocollethis spp.
B.315 CryllIA Frankliniella spp. B.342 CrylllB2 Lobesia botrana
B.316 CryllIA Thrips spp. B.343 CrylllB2 Ostrinia nubilalis
B.317 CryllIA Scirtothrips aurantii B.344 CryIIIB2 Pandemis spp.
B.318 CryllIA Aceria spp. B.345 CrylllB2 Pectinophora
B.319 CrylllA Aculus spp. gossyp.
B.320 CryllIA Brevipalpus spp. B.346 CryIIIB2 Phyllocnistis citrella
B.321 CryllIA Panonychus spp. B.347 CryIIIB2 Pieris spp.
B.322 CryIIIA Phyllocoptruta spp. B.348 CrylIIB2 Plutella xylostella
B.323 CryllIA Tetranychus spp. B.349 CrylIIB2 Scirpophaga spp.
B.324 CryllIA Heterodera spp. B.350 CryIIIB2 Sesamia spp.


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AP Control of AP Control of

B.351 CrylIIB2 Sparganothis spp. B.381 CrylIIB2 Thrips spp.
B.352 CrylIIB2 Spodoptera spp. B.382 CrylIIB2 Scirtothrips aurantii
B.353 CrylIIB2 Tortrix spp. B.383 CrylllB2 Aceria spp.
B.354 CrylIIB2 Trichoplusia ni B.384 CrylllB2 Aculus spp.
B.355 CrylllB2 Agriotes spp. B.385 CrylllB2 Brevipalpus spp.
B.356 CrylllB2 Anthonomus B.386 CrylIIB2 Panonychus spp.
grandis B.387 CrylIIB2 Phyllocoptruta spp.
B.357 CrylIIB2 Curculio spp. B.388 CrylIIB2 Tetranychus spp.
B.358 CrylIIB2 Diabrotica balteata B.389 CrylIIB2 Heterodera spp.
B.359 CrylIIB2 Leptinotarsa spp. B.390 CrylIIB2 Meloidogyne spp.
B.360 CrylIIB2 Lissorhoptrus spp. B.391 CytA Adoxophyes spp.
B.361 CrylIIB2 Otiorhynchus spp. B.392 CytA Agrotis spp.
B.362 CrylllB2 Aleurothrixus spp. B.393 CytA Alabama
B.363 CrylIIB2 Aleyrodes spp. argillaceae
B.364 CrylllB2 Aonidiella spp. B.394 CytA Anticarsia
B.365 CrylIIB2 Aphididae spp. gemmatalis
B.366 CrylllB2 Aphis spp. B.395 CytA Chilo spp.
B.367 CrylIIB2 Bemisia tabaci B.396 CytA Clysia ambiguella
B.368 CrylIIB2 Empoasca spp. B.397 CytA Crocidolomia
B.369 CrylllB2 Mycus spp. binotalis
B.370 CrylIIB2 Nephotettix spp. B.398 CytA Cydia spp.
B.371 CrylIIB2 Nilaparvata spp. B.399 CytA Diparopsis
B.372 CrylIIB2 Pseudococcus spp. castanea
B.373 CrylIIB2 Psylla spp. B.400 CytA Earias spp.
B.374 CrylllB2 Ouadraspidiotus B.401 CytA Ephestia spp.
spp. B.402 CytA Heliothis spp.
B.375 CrylIIB2 Schizaphis spp. B.403 CytA Hellula undalis
B.376 CrylIIB2 Trialeurodes spp. B.404 CytA Keiferia
B.377 CrylllB2 Lyriomyza spp. lycopersicella
B.378 CrylIIB2 Oscinella spp. B.405 CytA Leucoptera scitella
B.379 CrylllB2 Phorbia spp. B.406 CytA Lithocollethis spp.
B.380 CrylIIB2 Frankliniella spp. B.407 CytA Lobesia botrana


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-71-
AP Control of AP Control of

B.408 CytA Ostrinia nubilalis B.438 CytA Psylla spp.
B.409 CytA Pandemis spp. B.439 CytA Quadraspidiotus
B.410 CytA Pectinophora spp.
gossyp. B.440 CytA Schizaphis spp.
B.411 CytA Phyllocnistis citrella B.441 CytA Trialeurodes spp.
B.412 CytA Pieris spp.- B.442 CytA Lyriomyza spp.
B.413 CytA Plutella xylostella B.443 CytA Oscinella spp.
B.414 CytA Scirpophaga spp. B.444 CytA Phorbia spp.
B.415 CytA Sesamia spp. B.445 CytA Frankliniella spp.
B.416 CytA Sparganothis spp. B.446 CytA Thrips spp.
B.417 CytA Spodoptera spp. B.447 CytA Scirtothrips aurantii
B.418 CytA Tortrix spp. B.448 CytA Aceria spp.
B.419 CytA Trichoplusia ni B.449 CytA Aculus spp.
B.420 CytA Agriotes spp. B.450 CytA Brevipalpus spp.
B.421 CytA Anthonomus B.451 CytA Panonychus spp.
grandis B.452 CytA Phyllocoptruta spp.
B.422 CytA Curculio spp. B.453 CytA Tetranychus spp.
B.423 CytA Diabrotica balteata B.454 CytA Heterodera spp.
B.424 CytA Leptinotarsa spp. B.455 CytA Meloidogyne spp.
B.425 CytA Lissorhoptrus spp. B.456 VIP3 Adoxophyes spp.
B.426 CytA Otiorhynchus spp. B.457 VIP3 Agrotis spp.
B.427 CytA Aleurothrixus spp. B.458 VIP3 Alabama
B.428 CytA Aleyrodes spp. argillaceae
B.429 CytA Aonidiella spp. B.459 VIP3 Anticarsia
B.430 CytA Aphididae spp. gemmatalis
B.431 CytA Aphis spp. B.460 VIP3 Chilo spp.
B.432 CytA Bemisia tabaci B.461 VIP3 Clysia ambiguella
B.433 CytA Empoasca spp. B.462 VIP3 Crocidolomia
B.434 CytA Mycus spp. binotalis
B.435 CytA Nephotettix spp. B.463 VIP3 Cydia spp.
B.436 CytA Nilaparvata spp. B.464 VIP3 Diparopsis
B.437 CytA Pseudococcus spp. castanea


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-72-
AP Control of AP Control of

B.465 VIP3 Earias spp. B.494 VIP3 Aonidiella spp.
B.466 VIP3 Ephestia spp. B.495 VIP3 Aphididae spp.
B.467 VIP3 Heliothis spp. B.496 VIP3 Aphis spp.
B.468 VIP3 Hellula undalis B.497 VIP3 Bemisia tabaci
B.469 VIP3 Keiferia B.498 VIP3 Empoasca spp.
lycopersicella B.499 VIP3 Mycus spp.
B.470 VIP3 Leucoptera scitella B.500 VIP3 Nephotettix spp.
B.471 VIP3 Lithocollethis spp. B.501 VIP3 Nilaparvata spp.
B.472 VIP3 Lobesia botrana B.502 VIP3 Pseudococcus spp.
B.473 VIP3 Ostrinia nubilalis B.503 VIP3 Psylla spp.
B.474 VIP3 Pandemis spp. B.504 VIP3 Quadraspidiotus
B.475 VIP3 Pectinophora spp.
gossyp. B.505 VIP3 Schizaphis spp.
B.476 VIP3 Phyllocnistis citrella B.506 VIP3 Trialeurodes spp.
B.477 VIP3 Pieris spp. B.507 VIP3 Lyriomyza spp.
B.478 VIP3 Plutella xylostella B.508 VIP3 Oscinella spp.
B.479 VIP3 Scirpophaga spp. B.509 VIP3 Phorbia spp.
B.480 VIP3 Sesamia spp. B.510 VIP3 Frankliniella spp.
B.481 VIP3 Sparganothis spp. B.511 VIP3 Thrips spp.
B.482 VIP3 Spodoptera spp. B.512 VIP3 Scirtothrips aurantii
B.483 VIP3 Tortrix spp. B.513 VIP3 Aceria spp.
B.484 VIP3 Trichoplusia ni B.514 VIP3 Aculus spp.
B.485 VIP3 Agriotes spp. B.515 VIP3 Brevipalpus spp.
B.486 VIP3 Anthonomus B.516 VIP3 Panonychus spp.
grandis B.517 VIP3 Phyllocoptruta spp.
B.487 VIP3 Curculio spp. B.518 VIP3 Tetranychus spp.
B.488 VIP3 Diabrotica balteata B.519 VIP3 Heterodera spp.
B.489 VIP3 Leptinotarsa spp. B.520 VIP3 Meloidogyne spp.
B.490 VIP3 Lissorhoptrus spp. B.521 GL Adoxophyes spp.
B.491 VIP3 Otiorhynchus spp. B.522 GL Agrotis spp.
B.492 VIP3 Aleurothrixus spp. B.523 GL Alabama
B.493 VIP3 Aleyrodes spp. argillaceae


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-73-
AP Control of AP Control of

B.524 GL Anticarsia B.551 GL Anthonomus
gemmatalis grandis
B.525 GL Chilo spp. B.552 GL Curculio spp.
B.526 GL Clysia ambiguella B.553 GL Diabrotica balteata
B.527 GL Crocidolomia B.554 GL Leptinotarsa spp.
binotalis B.555 GL Lissorhoptrus spp.
B.528 GL Cydia spp. B.556 GL Otiorhynchus spp.
B.529 GL Diparopsis B.557 GL Aleurothrixus spp.
castanea B.558 GL Aleyrodes spp.
B.530 GL Earias spp. B.559 GL Aonidiella spp.
B.531 GL Ephestia spp. B.560 GL Aphididae spp.
B.532 GL Heliothis spp. B.561 GL Aphis spp.
B.533 GL Hellula undalis B.562 GL Bemisia tabaci
B.534 GL Keiferia B.563 GL Empoasca spp.
lycopers'icella B.564 GL Mycus spp.
B.535 GL Leucoptera scitella B.565 GL Nephotettix spp.
B.536 GL Lithocollethis spp. B.566 GL Nilaparvata spp.
B.537 GL Lobesia botrana B.567 GL Pseudococcus spp.
B.538 GL Ostrinia nubilalis B.568 GL Psylla spp.
B.539 GL Pandemis spp. B.569 GL Quadraspidiotus
B.540 GL Pectinophora spp.
gossyp. B.570 GL Schizaphis spp.
B.541 GL Phyllocnistis citrella B.571 GL Trialeurodes spp.
B.542 GL Pieris spp. B.572 GL Lyriomyza spp.
B.543 GL Plutella xylostella B.573 GL Oscinella spp.
B.544 GL Scirpophaga spp. B.574 GL Phorbia spp.
B.545 GL Sesamia spp. B.575 GL Frankliniella spp.
B.546 GL Sparganothis spp. B.576 GL Thrips spp.
B.547 GL Spodoptera spp. B.577 GL Scirtothrips aurantii
B.548 GL Tortrix spp. B.578 GL Aceria spp.
B.549 GL Trichoplusia ni B.579 GL Aculus spp.
B.550 GL Agriotes spp. B.580 GL Brevipalpus spp.


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-74-
AP Control of AP Control of

B.581 GL Panonychus spp. B.607 PL Pieris spp.
B.582 GL Phyllocoptruta spp. B.608 PL Plutella xylostella
B.583 GL Tetranychus spp. B.609 PL Scirpophaga spp.
B.584 GL Heterodera spp. B.610 PL Sesamia spp.
B.585 GL Meloidogyne spp. B.611 PL Sparganothis spp.
B.586 PL Adoxophyes spp. B.612 PL Spodoptera spp.
B.587 PL Agrotis spp. B.613 PL Tortrix spp.
B.588 PL Alabama B.614 PL Trichoplusia ni
argillaceae B.615 PL Agriotes spp.
B.589 PL Anticarsia B.616 PL Anthonomus
gemmatalis grandis
B.590 PL Chilo spp. B.617 PL Curculio spp.
B.591 PL Clysia ambiguella B.618 PL Diabrotica balteata
B.592 PL Crocidolomia B.619 PL Leptinotarsa spp.
binotalis B.620 PL Lissorhoptrus spp.
B.593 PL Cydia spp. B.621 PL Otiorhynchus spp.
B.594 PL Diparopsis B.622 PL Aleurothrixus spp.
castanea B.623 PL Aleyrodes spp.
B.595 PL Earias spp. B.624 PL Aonidiella spp.
B.596 PL Ephestia spp. B.625 PL Aphididae spp.
B.597 PL Heliothis spp. B.626 PL Aphis spp.
B.598 PL Hellula undalis B.627 PL Bemisia tabaci
B.599 PL Keiferia B.628 PL Empoasca spp.
iycopersicella B.629 PL Mycus spp.
B.600 PL Leucoptera scitella B.630 PL Nephotettix spp.
B.601 PL Lithocofethis spp. B.631 PL Nilaparvata spp.
B.602 PL Lobesia botrana B.632 PL Pseudococcus spp.
B.603 PL Ostrinia nubilalis B.633 PL Psylia spp.
B.604 PL Pandemis spp. B.634 PL Quadraspidiotus
B.605 PL Pectinophora spp.
gossyp. B.635 PL Schizaphis spp.
B.606 PL Phytlocnistis citrella B.636 PL Trialeurodes spp.


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
AP Control of AP Control of

B.637 PL Lyriomyza spp. lycopersicella
B.638 PL Oscinella spp. B.665 XN Leucoptera scitella
B.639 PL Phorbia spp. B.666 XN Lithocollethis spp.
B.640 PL Frankliniella spp. B.667 XN Lobesia botrana
B.641 PL Thrips spp. B.668 XN Ostrinia nubilalis
B.642 PL Scirtothrips aurantii B.669 XN Pandemis spp.
B.643 PL Aceria spp. B.670 XN Pectinophora
B.644 PL Aculus spp. gossyp.
B.645 PL Brevipalpus spp. B.671 XN Phyllocnistis citrella
B.646 PL Panonychus spp. B.672 XN Pieris spp.
B.647 PL Phyllocoptruta spp. B.673 XN Plutella xylostella
B.648 PL Tetranychus spp. B.674 XN Scirpophaga spp.
B.649 PL Heterodera spp. B.675 XN Sesamia spp.
B.650 PL Meloidogyne spp. B.676 XN Sparganothis spp.
B.651 XN Adoxophyes spp. B.677 XN Spodoptera spp.
B.652 XN Agrotis spp. B.678 XN Tortrix spp.
B.653 XN Alabama B.679 XN Trichoplusia ni
argillaceae B.680 XN Agriotes spp.
B.654 XN Anticarsia B.681 XN Anthonomus
gemmatalis grandis
B.655 XN Chilo spp. B.682 XN Curculio spp.
B.656 XN Clysia ambiguella B.683 XN Diabrotica balteata
B.657 XN Crocidolomia B.684 XN Leptinotarsa spp.
binotalis B.685 XN Lissorhoptrus spp.
B.658 XN Cydia spp. B.686 XN Otiorhynchus app.
B.659 XN Diparopsis B.687 XN Aleurothrixus spp.
castanea B.688 XN Aleyrodes spp.
B.660 XN Earias spp. B.689 XN Aonidiella spp.
B.661 XN Ephestia spp. B.690 XN Aphididae spp.
B.662 XN Heliothis spp. B.691 XN Aphis spp.
B.663 XN Hellula undalis B.692 XN Bemisia tabaci
B.664 XN Keiferia B.693 XN Empoasca spp.


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-76-
AP Control of AP Control of

B.694 XN Mycus spp. binotalis
B.695 XN Nephotettix spp. B.723 Plnh. Cydia spp.
B.696 XN Nilaparvata spp. B.724 Pinh. Diparopsis
B.697 XN Pseudococcus spp. castanea
B.698 XN Psylla spp. B.725 Plnh. Earias spp.
B.699 XN Quadraspidiotus B.726 Pinh. Ephestia spp.
spp. B.727 Pinh. Heliothis spp.
B.700 XN Schizaphis spp. B.728 Plnh. Hellula undalis
B.701 XN Trialeurodes spp. B.729 Plnh. Keiferia
B.702 XN Lyriomyza spp. lycopersicella
B.703 XN Oscinella spp. B.730 Plnh. Leucoptera scitella
B.704 XN Phorbia spp. B.731 Pinh. Lithocollethis spp.
B.705 XN Frankliniella spp. B.732 Plnh. Lobesia botrana
B.706 XN Thrips spp. B.733 Plnh. Ostrinia nubilalis
B.707 XN Scirtothrips aurantii B.734 Plnh. Pandemis spp.
B.708 XN Aceria spp. B.735 Plnh. Pectinophora
B.709 XN Aculus spp. gossyp.
B.710 XN Brevipalpus spp. B.736 Plnh. Phyllocnistis citrella
B.711 XN Panonychus spp. B.737 Plnh. Piers spp.
B.712 XN Phyllocoptruta spp. B.738 Plnh. Plutella xylostella
B.713 XN Tetranychus spp. B.739 Plnh. Scirpophaga spp.
B.714 XN Heterodera spp. B.740 Plnh. Sesamia spp.
B.715 XN Meloidogyne spp. B.741 Plnh. Sparganothis spp.
B.716 Plnh. Adoxophyes spp. B.742 Plnh. Spodoptera spp.
B.717 Pinh. Agrotis spp. B.743 Plnh. Tortrix spp.
B.718 Plnh. Alabama B.744 Plnh. Trichoplusia ni
argillaceae B.745 Pinh. Agriotes spp.
B.719 Plnh. Anticarsia B.746 Pinh. Anthonomus
gemmatalis grandis
B.720 Plnh. Chilo spp. B.747 Plnh. Curculio spp.
B.721 Plnh. Clysia ambiguella B.748 Plnh. Diabrotica balteata
B.722 Pinh. Crocidolomia B.749 Pinh. Leptinotarsa spp.


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-77-
AP Control of AP Control of

B.750 Pinh. Lissorhoptrus spp. B.781 Plec Adoxophyes spp.
B.751 Pinh. Otiorhynchus spp. B.782 Plec Agrotis spp.
B.752 Plnh. Aleurothrixus spp. B.783 Plec Alabama
B.753 Plnh. Aleyrodes spp. argillaceae
B.754 Plnh. Aonidiella spp. B.784 Plec Anticarsia
B.755 Plnh. Aphididae spp. gemmatalis
B.756 Pinh. Aphis spp. B.785 Plec Chilo spp.
B.757 Pinh. Bemisia tabaci B.786 Plec Clysia ambiguella
B.758 Pinh. Empoasca spp. B.787 Plec Crocidolomia
B.759 Plnh. Mycus spp. binotalis
B.760 Plnh. Nephotettix spp. B.788 Plec Cydia spp.
B.761 Plnh. Nilaparvata spp. B.789 Plec Diparopsis
B.762 Pinh. Pseudococcus spp. castanea
B.763 Pinh. Psylla spp. B.790 Plec Earias spp.
B.764 Pinh. Quadraspidiotus B.791 Plec Ephestia spp.
spp. B.792 Plec Heliothis spp.
B.765 Plnh. Schizaphis spp. B.793 Plec Hellula undalis
B.766 Plnh. Trialeurodes spp. B.794 Piec Keiferia
B.767 Pinh. Lyriomyza spp. lycopersicella
B.768 Pinh. Oscineila spp. B.795 Plec Leucoptera scitelia
B.769 Pinh. Phorbia spp. B.796 Plec Lithocollethis spp.
B.770 Plnh. Frankliniella spp. B.797 Plec Lobesia botrana
B.771 Pinh. Thrips spp. B.798 Plec Ostrinia nubilalis
B.772 Pinh. Scirtothrips aurantii B.799 Plec Pandemis spp.
B.773 Pinh. Aceria spp. B.800 Plec Pectinophora
B.774 Plnh. Aculus spp. gossyp.
B.775 Pinh. Brevipalpus spp. B.801 Plec Phyllocnistis citrella
B.776 Pinh. Panonychus spp. B.802 Plec Pieris spp.
B.777 Pinh. Phyllocoptruta spp. B.803 Plec Plutella xylostella
B.778 Pinh. Tetranychus spp. B.804 Plec Scirpophaga spp.
B.779 Plnh. Heterodera spp. B.805 Plec Sesamia spp.
B.780 Pinh. Meloidogyne spp. B.806 Plec Sparganothis spp.


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-78-
AP Control of AP Control of

B.807 Plec Spodoptera spp. B.837 Plec Scirtothrips aurantii
B.808 Plec Tortrix spp. B.838 Plec Aceria spp.
B.809 Plec Trichoplusia ni B.839 Plec Aculus spp.
B.810 Plec Agriotes spp. B.840 Plec Brevipalpus spp.
B.811 Plec Anthonomus B.841 Piec Panonychus spp.
grandis B.842 Plec Phyllocoptruta spp.
B.812 Plec Curculio spp. B.843 Plec Tetranychus spp.
B.813 Plec Diabrotica balteata B.844 Piec Heterodera spp.
B.814 Plec Leptinotarsa spp. B.845 Plec Meloidogyne spp.
B.815 Plec Lissorhoptrus spp. B.846 Aggi. Adoxophyes spp.
B.816 Plec Otiorhynchus spp. B.847 Aggl. Agrotis spp.
B.817 Plec Aleurothrixus spp. B.848 Aggl. Alabama
B.818 P1ec Aleyrodes spp. argillaceae
B.819 Plec Aonidiella spp. B.849 Aggi. Anticarsia
B.820 Plec Aphididae spp. gemmatalis
B.821 Plec Aphis spp. B.850 Aggi. Chilo spp.
B.822 Plec Bemisia tabaci B.851 Aggi. Clysia ambiguella
B.823 Plec Empoasca spp. B.852 Aggl. Crocidolomia
B.824 Plec Mycus spp. binotalis
B.825 Plec Nephotettix spp. B.853 Aggl. Cydia spp.
B.826 Plec Nilaparvata spp. B.854 Aggl. Diparopsis
B.827 Plec Pseudococcus spp. castanea
B.828 Plec Psylla spp. B.855 Aggi. Earias spp.
B.829 Plec Quadraspidiotus B.856 Aggl. Ephestia spp.
spp. B.857 Aggl. Heliothis spp.
B.830 Plec Schizaphis spp. B.858 Aggl. Hellula undalis
B.831 Plec Trialeurodes spp. B.859 Aggl. Keiferia
B.832 Plec Lyriomyza spp. lycopersicella
B.833 Plec Oscinella spp. B.860 Aggi. Leucoptera scitella
B.834 Plec Phorbia spp. B.861 Aggi. Lithocollethis spp.
B.835 Plec Frankliniella spp. B.862 Aggi. Lobesia botrana
B.836 Plec Thrips spp. B.863 Aggi. Ostrinia nubilalis


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-79-
AP Control of AP Control of

B.864 Aggi. Pandemis spp. B.894 Aggl. Quadraspidiotus
B.865 Aggl. Pectinophora spp.
gossyp. B.895 Aggl. Schizaphis spp.
B.866 Aggl. Phyllocnistis citrella B.896 Aggl. Trialeurodes spp.
B.867 Aggl. Pieris spp. B.897 Aggl. Lyriomyza spp.
B.868 Aggi. Plutella xylostella B.898 Aggi. Oscinella spp.
B.869 Aggi. Scirpophaga spp. B.899 Aggl. Phorbia spp.
B.870 Aggi. Sesamia spp. B.900 Aggl. Frankliniella spp.
B.871 Aggl. Sparganothis spp. B.901 Aggl. Thrips spp.
B.872 Aggi. Spodoptera spp. B.902 Aggl. Scirtothrips aurantii
B.873 Aggl. Tortrix spp. B.903 Aggi. Aceria spp.
B.874 Aggi. Trichoplusia ni B.904 Aggl. Aculus spp.
B.875 Aggl. Agriotes spp. B.905 Aggl. Brevipalpus spp.
B.876 Aggl. Anthonomus B.906 Aggi. Panonychus spp.
grandis B.907 Aggl. Phyllocoptruta spp.
B.877 Aggl. Curculio spp. B.908 Aggi. Tetranychus spp.
B.878 Aggi. Diabrotica balteata B.909 Aggl. Heterodera spp.
B.879 Aggi. Leptinotarsa spp. B.910 Aggi. Meloidogyne spp.
B.880 Aggi. Lissorhoptrus spp. B.911 CO Adoxophyes spp.
B.881 Aggl. Otiorhynchus spp. B.912 CO Agrotis spp.
B.882 Aggl. Aleurothrixus spp. B.913 CO Alabama
B.883 Aggl. Aleyrodes spp. argillaceae
B.884 Aggl. Aonidiella spp. B.914 CO Anticarsia
B.885 Aggl. Aphididae spp. gemmatalis
B.886 Aggl. Aphis spp. B.915 CO Chilo spp.
B.887 Aggl. Bemisia tabaci B.916 CO Clysia ambiguella
B.888 Aggl. Empoasca spp. B.917 CO Crocidolomia
B.889 Aggl. Mycus spp. binotalis
B.890 Aggi Nephotettix spp. B.918 CO Cydia spp.
B.891 Aggl. Nilaparvata spp. B.919 CO Diparopsis
B.892 Aggi. Pseudococcus spp. castanea
B.893 Aggl. Psylla spp. B.920 CO Earias spp.


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-80-
AP Control of AP Control of

B.921 CO Ephestia spp. B.950 CO Aphididae spp.
B.922 CO Heliothis spp. B.951 CO Aphis spp.
B.923 CO Hellula undalis B.952 CO Bemisia tabaci
B.924 CO Keiferia B.953 CO Empoasca spp.
lycopersicella B.954 CO Mycus spp.
B.925 CO Leucoptera scitella B.955 CO Nephotettix spp.
B.926 CO Lithocollethis spp. B.956 CO Nilaparvata spp.
B.927 CO Lobesia botrana B.957 CO Pseudococcus spp.
B.928 CO Ostrinia nubilalis B.958 CO Psylla spp.
B.929 CO Pandemis spp. B.959 CO Quadraspidiotus
B.930 CO Pectinophora spp.
gossyp. B.960 CO Schizaphis spp.
B.931 CO Phyllocnistis citrella B.961 CO Trialeurodes spp.
B.932 CO Pieris spp. B.962 CO Lyriomyza spp.
B.933 CO Plutella xylostella B.963 CO Oscinella spp.
B.934 CO Scirpophaga spp. B.964 CO Phorbia spp.
B.935 CO Sesamia spp. B.965 CO Frankliniella spp.
B.936 CO Sparganothis spp. B.966 CO Thrips spp.
B.937 CO Spodoptera spp. B.967 CO Scirtothrips aurantii
B.938 CO Tortrix spp. B.968 CO Aceria spp.
B.939 CO Trichoplusia ni B.969 CO Aculus spp.
B.940 CO Agriotes spp. B.970 CO Brevipalpus spp.
B.941 CO Anthonomus B.971 CO Panonychus spp.
grandis B.972 CO Phyllocoptruta spp.
B.942 CO Curculio spp. B.973 CO Tetranychus spp.
B.943 CO Diabrotica balteata B.974 CO Heterodera spp.
B.944 CO Leptinotarsa spp. B.975 CO Meloidogyne spp.
B.945 CO Lissorhoptrus spp. B.976 CH Adoxophyes spp.
B.946 CO Otiorhynchus spp. B.977 CH Agrotis spp.
B.947 CO Aleurothrixus spp. B.978 CH Alabama
B.948 CO Aleyrodes spp. argillaceae
B.949 CO Aonidiella spp. B.979 CH Anticarsia


CA 02318331 2000-06-13

WO 99/33343 PCT/EP98/08384
-81-
AP Control of AP Control of

gemmataiis grandis
B.980 CH Chilo spp. B.1007 CH Curculio spp.
B.981 CH Clysia ambiguella B.1008 CH Diabrotica balteata
B.982 CH Crocidolomia B.1009 CH Leptinotarsa spp.
binotalis B.1010 CH Lissorhoptrus spp.
B.983 CH Cydia spp. B.1011 CH Otiorhynchus spp.
B.984 CH Diparopsis B.1012 CH Aleurothrixus spp.
castanea B.1013 CH Aleyrodes spp.
B.985 CH Earias spp. B.1014 CH Aonidiella spp.
B.986 CH Ephestia spp. B.1015 CH Aphididae spp.
B.987 CH Heliothis spp. B.1016 CH Aphis spp.
B.988 CH Hellula undalis B.1017 CH Bemisia tabaci
B.989 CH Keiferia B.1018 CH Empoasca spp.
lycopersicella B.1019 CH Mycus spp.
B.990 CH Leucoptera scitella B.1020 CH Nephotettix spp.
B.991 CH Lithocollethis spp. B.1021 CH Nilaparvata spp.
B.992 CH Lobesia botrana B.1022 CH Pseudococcus spp.
B.993 CH Ostrinia nubilalis B.1023 CH Psylla spp.
B.994 CH Pandemis spp. B.1024 CH Quadraspidiotus
B.995 CH Pectinophora spp.
gossyp. B.1025 CH Schizaphis spp.
B.996 CH Phyllocnistis citrella B.1026 CH Trialeurodes spp.
B.997 CH Pieris spp. B.1027 CH Lyriomyza spp.
B.998 CH Plutella xylostella B.1028 CH Oscinella spp.
B.999 CH Scirpophaga spp. B.1029 CH Phorbia spp.
B.1000 CH Sesamia spp. B.1030 CH Frankliniella spp.
B.1001 CH Sparganothis spp. B.1031 CH Thrips spp.
B.1002 CH Spodoptera spp. B.1032 CH Scirtothrips aurantii
B.1003 CH Tortrix spp. B.1033 CH Aceria spp.
B.1004 CH Trichoplusia ni B.1034 CH Aculus spp.
B.1005 CH Agriotes spp. B.1035 CH Brevipalpus spp.
B.1006 CH Anthonomus B.1036 CH Panonychus spp.


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B.1037 CH Phyllocoptruta spp. B.1063 SS Plutella xylostella
B.1038 CH Tetranychus spp. B.1064 SS Scirpophaga spp.
B.1039 CH Heterodera spp. B.1065 SS Sesamia spp.
B.1040 CH Meloidogyne spp. B.1066 SS Sparganothis spp.
B.1041 SS Adoxophyes spp. B.1067 SS Spodoptera spp.
B.1042 SS Agrotis spp. B.1068 SS Tortrix spp.
B.1043 SS Alabama B.1069 SS Trichoplusia ni
argillaceae B.1070 SS Agriotes spp.
B.1044 SS Anticarsia B.1071 SS Anthonomus
gemmatalis grandis
B.1045 SS Chilo spp. B.1072 SS Curculio spp.
B.1046 SS Clysia ambiguella B.1073 SS Diabrotica balteata
B.1047 SS Crocidolomia B.1074 SS Leptinotarsa spp.
binotalis B.1075 SS Lissorhoptrus spp.
B.1048 SS Cydia spp. B.1076 SS Otiorhynchus spp.
B.1049 SS Diparopsis B.1077 SS Aleurothrixus spp.
castanea B.1078 SS Aleyrodes spp.
B.1050 SS Earias spp. B.1079 SS Aonidiella spp.
B.1051 SS Ephestia spp. B.1080 SS Aphididae spp.
B.1052 SS Heliothis spp. B.1081 SS Aphis spp.
B.1053 SS Hellula undalis B.1082 SS Bemisia tabaci
B.1054 SS Keiferia B.1083 SS Empoasca spp.
lycopersicella B. 1084 SS Mycus spp.
B.1055 SS Leucoptera scitella B.1085 SS Nephotettix spp.
B.1056 SS Lithocollethis spp. B.1086 SS Nilaparvata spp.
B.1057 SS Lobesia botrana B.1087 SS Pseudococcus spp.
B.1058 SS Ostrinia nubilalis B.1088 SS Psylla spp.
B.1059 SS Pandemis spp. B.1089 SS Quadraspidiotus
B. 1060 SS Pectinophora spp.
gossyp. B.1090 SS Schizaphis spp.
B.1061 SS Phyllocnistis citrella B.1091 SS Trialeurodes spp.
B. 1062 SS Pieris spp. B.1092 SS Lyriomyza spp.


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B. 1093 SS Oscinella spp. B. 1120 HO Leucoptera scitella
B.1094 SS Phorbia spp. B.1121 HO Lithocollethis spp.
B.1095 SS Frankliniella spp. B.1122 HO Lobesia botrana
B.1096 SS Thrips spp. B.1123 HO Ostrinia nubilalis
B.1097 SS Scirtothrips aurantii B.1124 HO Pandemis spp.
B.1098 SS Aceria spp. B.1125 HO Pectinophora
B.1099 SS Aculus spp. gossypiella
B.1100 SS Brevipalpus spp. B.1126 HO Phyllocnistis citrella
B.1101 SS Panonychus spp. B.1127 HO Pieris spp.
B.1102 SS Phyllocoptruta spp. B.1128 HO Plutella xylostella
B.1103 SS Tetranychus spp. B.1129 HO Scirpophaga spp.
B.1104 SS Heterodera spp. B.1130 HO Sesamia spp.
B.1105 SS Meloidogyne spp. B.1131 HO Sparganothis spp.
B. 1106 HO Adoxophyes spp. B.1132 HO Spodoptera spp.
B.1107 HO Agrotis spp. B.1133 HO Tortrix spp.
B.1108 HO Alabama B.1134 HO Trichoplusia ni
argillaceae B.1135 HO Agriotes spp.
B. 1109 HO Anticarsia B.1136 HO Anthonomus
gemmatalis grandis
B.1110 HO Chilo spp. B.1137 HO Curculio spp.
B.1111 HO Clysia ambiguella B.1138 HO Diabrotica balteata
B.1112 HO Crocidolomia B.1139 HO Leptinotarsa spp.
binotalis B.1140 HO Lissorhoptrus spp.
B.1 113 HO Cydia spp. B.1141 HO Otiorhynchus spp.
B. 1114 HO Diparopsis B. 1142 HO Aleurothrixus spp.
castanea B. 1143 HO Aleyrodes spp.
B.1115 HO Earias spp. B.1144 HO Aonidiella spp.
B.1116 HO Ephestia spp. B.1145 HO Aphididae spp.
B.1117 HO Heliothis spp. B.1146 HO Aphis spp.
B.1118 HO Hellula undalis B.1147 HO Bemisia tabaci
B.1119 HO Keiferia B.1148 HO Empoasca spp.
lycopersicella B. 1149 HO Mycus spp.


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B.1150 HO Nephotettix spp. B.1160 HO Frankliniella spp.
B. 1151 HO Nilaparvata spp. B.1161 HO Thrips spp.
B.1152 HO Pseudococcus spp. B.1162 HO Scirtothrips aurantii
B.1153 HO Psylla spp. B.1163 HO Aceria spp.
B.1154 HO Quadraspidiotus B.1164 HO Aculus spp.
spp. B.1165 HO Brevipaipus spp.
B.1155 HO Schizaphis spp. B.1166 HO Panonychus spp.
B.1156 HO Trialeurodes spp. B.1167 HO Phyllocoptruta spp.
B.1157 HO Lyriomyza spp. B.1168 HO Tetranychus spp.
B.1158 HO Oscinella spp. B.1169 HO Heterodera spp.
B.1159 HO Phorbia spp. B.1170 HO Meloidogyne spp.
Biological Examples

Table 1: A method of controlling pests comprising the application of Abamectin
to
transgenic cotton, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 2: A method of controlling pests comprising the application of Abamectin
to
transgenic rice, wherein the combination of the active principle expressed by
the transgenic
plant and the pest to be controlled correspond to a line of the table B.

Table 3: A method of controlling pests comprising the application of Abamectin
to
transgenic potatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 4: A method of controlling pests comprising the application of Abamectin
to
transgenic brassica, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 5: A method of controlling pests comprising the application of Abamectin
to
transgenic tomatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.


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Table 6: A method of controlling pests comprising the application of Abamectin
to
transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 7: A method of controlling pests comprising the application of Abamectin
to
transgenic soybeans, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 8: A method of controlling pests comprising the application of Abamectin
to
transgenic maize, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 9: A method of controlling pests comprising the application of Abamectin
to
transgenic wheat, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 10: A method of controlling pests comprising the application of
Abamectin to
transgenic bananas, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 11: A method of controlling pests comprising the application of
Abamectin to
transgenic citrus trees, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 12: A method of controlling pests comprising the application of
Abamectin to
transgenic pome fruit trees, wherein the combination of the active principle
expressed by
the transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 13: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic cotton, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 14: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic rice, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 15: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic potatoes, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.


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TT bl 16: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic tomatoes, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 17: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 18: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic soybeans, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 19: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic maize, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 20: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic wheat, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 21: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic bananas, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 22: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic orange trees, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 23: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic pome fruit, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 24: A method of controlling pests comprising the application of
Emamectin-Benzoate
to transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

Table 25: A method of controlling pests comprising the application of Spinosad
to
transgenic cotton, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.


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Table 26: A method of controlling pests comprising the application of Spinosad
to
transgenic rice, wherein the combination of the active principle expressed by
the transgenic
plant and the pest to be controlled correspond to a line of the table B.

Table 27: A method of controlling pests comprising the application of Spinosad
to
transgenic potatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 28: A method of controlling pests comprising the application of Spinosad
to
transgenic brassica, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 29: A method of controlling pests comprising the application of Spinosad
to
transgenic tomatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 30: A method of controlling pests comprising the application of Spinosad
to
transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 31: A method of controlling pests comprising the application of Spinosad
to
transgenic soybeans, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.

T bile 32: A method of controlling pests comprising the application of
Spinosad to
transgenic maize, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 33: A method of controlling pests comprising the application of Spinosad
to
transgenic wheat, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table 34: A method of controlling pests comprising the application of Spinosad
to
transgenic bananas, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table A method of controlling pests comprising the application of Spinosad to
transgenic citrus trees, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to a line of the
table B.


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Table 36: A method of controlling pests comprising the application of Spinosad
to
transgenic pome fruit trees, wherein the combination of the active principle
expressed by
the transgenic plant and the pest to be controlled correspond to a line of the
table B.
Table C:
Abbreviations:
Acetyl-COA Carboxylase: ACCase
Acetolactate Synthase: ALS
Hydroxyphenylpyruvat dioxygenase: HPPD
Inhibition of protein synthesis: IPS
Hormone mimic: HO
Glutamine Synthetase: GS
Protoporphyrinogen oxidase: PROTOX
5-Enolpyruvyl-3-Phosphoshikimate Synthase: EPSPS

Principle Tolerant to Crop
C.1 ALS Sulfonylureas etc.*** Cotton
C.2 ALS Sulfonylureas etc. '** Rice
C.3 ALS Sulfonylureas etc. Brassica
C.4 ALS Sulfonylureas etc. *** Potatoes
C.5 ALS Sulfonylureas etc. *** Tomatoes
C.6 ALS Sulfonylureas etc. '** Cucurbits
C.7 ALS Sulfonylureas etc. `** Soybeans
C.8 ALS Sulfonylureas etc. Maize
C.9 ALS Sulfonylureas etc. **` Wheat
C.10 ALS Sulfonylureas etc. pome fruit
C.11 ALS Sulfonylureas etc. stone fruit
C.12 ALS Sulfonylureas etc. citrus
C.13 ACCase +++ Cotton
C.14 ACCase +++ Rice
C.15 ACCase +++ Brassica
C.16 ACCase +++ Potatoes
C.17 ACCase +++ Tomatoes


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Principle Tolerant to Crop

C.18 ACCase +++ Cucurbits
C.19 ACCase +++ Soybeans
C.20 ACCase +++ Maize
C.21 ACCase +++ Wheat
C.22 ACCase +++ pome fruit
C.23 ACCase +++ stone fruit
C.24 ACCase +++ citrus
C.25 HPPD Isoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion Cotton
C.26 HPPD Isoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion Rice
C.27 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Mesotrion Brassica
C.28 HPPD Isoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion Potatoes
C.29 HPPD Isoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion Tomatoes
C.30 HPPD Isoxaflutol, lsoxachlotol, Sulcotnon, Mesotrion Cucurbits
C.31 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Soybeans
C.32 HPPD Isoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion Maize
C.33 HPPD Isoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion Wheat
C.34 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Mesotrion pome fruit
C.35 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion stone fruit
C.36 HPPD Isoxaflutol, Isoxachlotol, Sulcotrion, Mesotrion citrus
C.37 Nitrilase Bromoxynil, loxynil Cotton
C.38 Nitrilase Bromoxynil, loxynil Rice
C.39 Nitrilase Bromoxynil, loxynil Brassica
C.40 Nitrilase Bromoxynil, loxynil Potatoes
C.41 Nitrilase Bromoxynil, loxynil Tomatoes
C.42 Nitrilase Bromoxynil, loxynil Cucurbits
C.43 Nitrilase Bromoxynil, loxynil Soybeans
C.44 Nitrilase Bromoxynil, loxynil Maize
C.45 Nitrilase Bromoxynil, loxynil Wheat
C.46 Nitrilase Bromoxynil, loxynil pome fruit
C.47 Nitrilase Bromoxynil, loxynil stone fruit
C.48 Nitrilase Bromoxynil, loxynil citrus
C.49 IPS Chloroactanilides &&& Cotton


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Principle Tolerant to Crop

C.50 IPS Chloroactanilides &&& Rice
C.51 IPS Chloroactanilide &&&s Brassica
C.52 IPS Chloroactanilides &&& Potatoes
C.53 IPS Chloroactanilides &&& Tomatoes
C.54 IPS Chloroactanilides &&& Cucurbits
C.55 IPS Chloroactanilides &&& Soybeans
C.56 IPS Chloroactanilides &&& Maize
C.57 IPS Chloroactanilides &&& Wheat
C.58 IPS Chloroactanilides &&& pome fruit
C.59 IPS Chloroactanilides &&& stone fruit
C.60 IPS Chloroactanilides &&& citrus
C.61 HOM 2,4-D, Mecoprop-P Cotton
C.62 HOM 2,4-D, Mecoprop-P Rice
C.63 HOM 2,4-D, Mecoprop-P Brassica
C.64 HOM 2,4-D, Mecoprop-P Potatoes
C.65 HOM 2,4-D, Mecoprop-P Tomatoes
C.66 HOM 2,4-D, Mecoprop-P Cucurbits
C.67 HOM 2,4-D, Mecoprop-P Soybeans
C.68 HOM 2,4-D, Mecoprop-P Maize
C.69 HOM 2,4-D, Mecoprop-P Wheat
C.70 HOM 2,4-D, Mecoprop-P pome fruit
C.71 HOM 2,4-D, Mecoprop-P stone fruit
C.72 HOM 2,4-D, Mecoprop-P citrus
C.73 PROTOX Protox inhibitors Cotton
C.74 PROTOX Protox inhibitors Rice
C.75 PROTOX Protox inhibitors Brassica
C.76 PROTOX Protox inhibitors Potatoes
C.77 PROTOX Protox inhibitors Tomatoes
C.78 PROTOX Protox inhibitors Cucurbits
C.79 PROTOX Protox inhibitors Soybeans
C.80 PROTOX Protox inhibitors/// Maize
C.81 PROTOX Protox inhibitors /// Wheat


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Principle Tolerant to Crop

C.82 PROTOX Protox inhibitors pome fruit
C.83 PROTOX Protox inhibitors /// stone fruit
C.84 PROTOX Protox inhibitors /// citrus
C.85 EPSPS Glyphosate and /or Suiphosate Cotton
C.86 EPSPS Glyphosate and for Suiphosate Rice
C.87 EPSPS Glyphosate and /or Suiphosate Brassica
C.88 EPSPS Glyphosate and for Suiphosate Potatoes
C.89 EPSPS Glyphosate and /or Suiphosate Tomatoes
C.90 EPSPS Glyphosate and /or Suiphosate Cucurbits
C.91 EPSPS Glyphosate and /or Suiphosate Soybeans
C.92 EPSPS Glyphosate and /or Suiphosate Maize
C.93 EPSPS Glyphosate and /or Suiphosate Wheat
C.94 EPSPS Glyphosate and for Suiphosate pome fruit
C.95 EPSPS Glyphosate and for Suiphosate stone fruit
C.96 EPSPS Glyphosate and /or Suiphosate citrus
C.97 GS Gluphosinate and for Bialaphos Cotton
C.98 GS Gluphosinate and /or Bialaphos Rice
C.99 GS Gluphosinate and /or Bialaphos Brassica
C.100 GS Gluphosinate and /or Bialaphos Potatoes
C.101 GS Gluphosinate and /or Bialaphos Tomatoes
C. 102 GS Gluphosinate and /or Bialaphos Cucurbits
C. 103 GS Gluphosinate and /or Bialaphos Soybeans
C.104 GS Gluphosinate and /or Bialaphos Maize
C.105 GS Gluphosinate and /or Bialaphos Wheat
C. 106 GS Gluphosinate and /or Bialaphos pome fruit
C.107 GS Gluphosinate and /or Bialaphos stone fruit
C.108 GS Gluphosinate and /or Bialaphos citrus

"' Included are Sulfonylureas, Imidazolinones, Triazolopyrimidines,
Dimethoxypyrimidines
and N-Acylsulfonamides:
Suifonylureas such as Chiorsulfuron, Chlorimuron, Ethamethsulfuron,
Metsulfuron,
Primisulfuron, Prosulfuron, Triasulfuron, Cinosulfuron, Trifusulfuron,
Oxasulfuron,


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Bensulfuron, Tribenuron, ACC 322140, Fluzasulfuron, Ethoxysulfuron,
Fluzasdulfuron,
Nicosulfuron, Rimsulfuron, Thifensulfuron, Pyrazosulfuron, Clopyrasulfuron, NC
330,
Azimsulfuron, Imazosulfuron, Sulfosulfuron, Amidosulfuron, Flupyrsulfuron, CGA
362622
Imidazolinones such as Imazamethabenz, Imazaquin, Imazamethypyr, Imazethapyr,
Imazapyr and Imazamox;

Triazolopyrimidines such as DE 511, Flumetsulam and Chloransulam;
Dimethoxypyrimidines such as Pyrithiobac, Pyriminobac, Bispyribac and
Pyribenzoxim.
+++ Tolerant to Diclofop-methyl, Fluazifop-P-butyl, Haloxyfop-P-methyl,
Haloxyfop-P-ethyl,
Quizalafop-P-ethyl , clodinafop propargyl, fenoxaprop - -ethyl, -
Tepraloxydim, Alloxydim,
Sethoxydim, Cycloxydim, Cloproxydim, Tralkoxydim, Butoxydim, Caloxydim,
Clefoxydim,
Clethodim.

&&& Chloroacetanilides such as Alachlor Acetochlor, Dimethenamid

/// Protox inhibitors: For instance diphenyethers such as Acifluorfen,
Aclonifen, Bifenox,
Chlornitrofen, Ethoxyfen, Fluoroglycofen, Fomesafen, Lactofen, Oxyfluorfen;
Imides such
as Azafenidin, Carfentrazone-ethyl, Cinidon-ethyl, Flumiclorac-pentyl,
Flumioxazin,
Fluthiacet-methyl, Oxadiargyl, Oxadiazon, Pentoxazone, Sulfentrazone, Imides
and
others,such as Flumipropyn, Flupropacil, Nipyraclofen and Thidiazimin; and
further
Fluazolate and Pyraflufen-ethyl

Biological Examples

Table 39: A method of controlling representatives of the genus Adoxophyes
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 40: A method of controlling representatives of the genus Agrotis
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 41: A method of controlling Alabama argillaceae comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active


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principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 42: A method of controlling Anticarsia gemmatalis comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 43: A method of controlling representatives of the genus Chilo
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

T ba le 44: A method of controlling Clysia ambiguella comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 45: A method of controlling representatives of the genus Cnephalocrocis
comprising
the application of Abamectin to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table
46: A method of controlling Crocidolomia binotalis comprising the application
of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 47: A method of controlling representatives of the genus Cydia
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table A method of controlling Diparopsis castanea comprising the application
of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.


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Table 49: A method of controlling representatives of the genus Earias
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 50: A method of controlling representatives of the genus Ephestia
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 51: A method of controlling representatives of the genus Heliothis
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 52: A method of controlling Hellula undalis comprising the application
of Abamectin to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 53: A method of controlling Keiferia lycopersicella comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 54: A method of controlling Leucoptera scitella comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 55: A method of controlling representatives of the genus Lithocollethis
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Tabl 56: A method of controlling Lobesia botrana comprising the application of
Abamectin
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle


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expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 57: A method of controlling Ostrinia nubilalis comprising the
application of Abamectin
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 58: A method of controlling representatives of the genus Pandemis
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 59: A method of controlling Pectinophora gossypielia comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 60: A method of controlling Phyllocnistis citrella comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 61: A method of controlling representatives of the genus Pieris
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 62: A method of controlling Plutella xylostella comprising the
application of Abamectin
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 63: A method of controlling representatives of the genus Scirpophaga
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.


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Table 64: A method of controlling representatives of the genus Sesamia
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 65: A method of controlling representatives of the genus Sparganothis
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 66: A method of controlling representatives of the genus Spodoptera
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 67: A method of controlling representatives of the genus Tortrix
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table A method of controlling Trichoplusia ni comprising the application of
Abamectin to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 69: A method of controlling representatives of the genus Agriotes
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table A method of controlling Anthonomus grandis comprising the application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 71: A method of controlling representatives of the genus Curculio
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination


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of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 72: A method of controlling Diabrotica balteata comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 73: A method of controlling representatives of the genus Leptinotarsa
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 74: A method of controlling representatives of the genus Lissorhoptrus
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 75: A method of controlling representatives of the genus Otiorhynchus
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 76: A method of controlling representatives of the genus Aleurothrixus
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 77: A method of controlling representatives of the genus Aleyrodes
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 78: A method of controlling representatives of the genus Aonidiella
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.


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Table 79: A method of controlling representatives of the family Aphididae
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 80: A method of controlling representatives of the genus Aphis
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 81: A method of controlling Bemisia tabaci comprising the application of
Abamectin to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 82: A method of controlling representatives of the genus Empoasca
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 83: A method of controlling representatives of the genus Mycus
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 84: A method of controlling representatives of the genus Nephotettix
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 85: A method of controlling representatives of the genus Nilaparvata
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 86: A method of controlling representatives of the genus Pseudococcus
comprising
the application of Abamectin to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 87: A method of controlling representatives of the genus Psylla
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 88: A method of controlling representatives of the genus Quadraspidiotus
comprising
the application of Abamectin to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 89: A method of controlling representatives of the genus Schizaphis
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 90: A method of controlling representatives of the genus Trialeurodes
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 91: A method of controlling representatives of the genus Lyriomyza
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 92: A method of controlling representatives of the genus Oscinella
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 93: A method of controlling representatives of the genus Phorbia
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.


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Table 94: A method of controlling representatives of the genus Frankliniella
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 95: A method of controlling representatives of the genus Thrips
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 96: A method of controlling Scirtothrips aurantii comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 97: A method of controlling representatives of the genus Aceria
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 98: A method of controlling representatives of the genus Aculus
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 99: A method of controlling representatives of the genus Brevipalpus
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 100: A method of controlling representatives of the genus Panonychus
comprising
the application of Abamectin to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 101: A method of controlling representatives of the genus Phyllocoptruta
comprising
the application of Abamectin to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 102: A method of controlling representatives of the genus Tetranychus
comprising
the application of Abamectin to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 103: A method of controlling representatives of the genus Heterodera
comprising the
application of Abamectin to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 104: A method of controlling representatives of the genus Meloidogyne
comprising
the application of Abamectin to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 105: A method of controlling Mamestra brassica comprising the
application of
Abamectin to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 106: A method of controlling representatives of the genus Adoxophyes
comprising
the application of Emamectin-Benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 107: A method of controlling representatives of the genus Agrotis
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 108: A method of controlling Alabama argillaceae comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.


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Table 109: A method of controlling Anticarsia gemmatalis comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 110: A method of controlling representatives of the genus Chilo
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 111: A method of controlling Clysia ambiguella comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 112: A method of controlling representatives of the genus Cnephalocrocis
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 113:: A method of controlling Crocidolomia binotalis comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 114: A method of controlling representatives of the genus Cydia
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 115: A method of controlling Diparopsis castanea comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 116: A method of controlling representatives of the genus Earias
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 117: A method of controlling representatives of the genus Ephestia
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 118: A method of controlling representatives of the genus Heliothis of
Emamectin-
benzoate to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 119: A method of controlling Hellula undalis comprising the application
of Emamectin-
benzoate to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 120: A method of controlling Keiferia lycopersicella comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 121: A method of controlling Leucoptera scitella comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 122: A method of controlling representatives of the genus Lithocollethis
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 123: A method of controlling Lobesia botrana comprising the application
of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.


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Table 124: A method of controlling Ostrinia nubilalis comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 125: A method of controlling representatives of the genus Pandemis
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 126: A method of controlling Pectinophora gossypiella comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 127: A method of controlling Phyllocnistis citrella comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 128: A method of controlling representatives of the genus Pieris
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 129: A method of controlling Plutella xylostella comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 130: A method of controlling representatives of the genus Scirpophaga
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 131: A method of controlling representatives of the genus Sesamia
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 132: A method of controlling representatives of the genus Sparganothis
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 133: A method of controlling representatives of the genus Spodoptera
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 134: A method of controlling representatives of the genus Tortrix
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant, and the
crop to be
protected against the pest correspond to a line of the table C.

Table 135: A method of controlling Trichoplusia ni comprising the application
of Emamectin-
benzoate to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 136: A method of controlling representatives of the genus Agriotes
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 137: A method of controlling Anthonomus grandis comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 138: A method of controlling representatives of the genus Curculio
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.


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Table 139: A method of controlling Diabrotica balteata comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 140: A method of controlling representatives of the genus Leptinotarsa
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 141: A method of controlling representatives of the genus Lissorhoptrus
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 142: A method of controlling representatives of the genus Otiorhynchus
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 143: A method of controlling representatives of the genus Aleurothrixus
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 144: A method of controlling representatives of the genus Aleyrodes
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 145: A method of controlling representatives of the genus Aonidiella
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 146: A method of controlling representatives of the family Aphididae
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 147: A method of controlling representatives of the genus Aphis
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 148: A method of controlling Bemisia tabaci comprising the application
of Emamectin-
benzoate to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 149: A method of controlling representatives of the genus Empoasca
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 150: A method of controlling representatives of the genus Mycus
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 151: A method of controlling representatives of the genus Nephotettix
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 152: A method of controlling representatives of the genus Nilaparvata
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 153: A method of controlling representatives of the genus Pseudococcus
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.


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Table 154: A method of controlling representatives of the genus Psylla
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 155: A method of controlling representatives of the genus
Quadraspidiotus
comprising the application of Emamectin-benzoate to a herbicidally resistant
transgenic
crop, wherein the combination of the active principle expressed by the
transgenic plant and
the crop to be protected against the pest correspond to a line of the table C.

Table 156: A method of controlling representatives of the genus Schizaphis
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 157: A method of controlling representatives of the genus Trialeurodes
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 158: A method of controlling representatives of the genus Lyriomyza
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 159: A method of controlling representatives of the genus Oscinella
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 160: A method of controlling representatives of the genus Phorbia
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 161: A method of controlling representatives of the genus Frankliniella
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 162: A method of controlling representatives of the genus Thrips
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 163: A method of controlling Scirtothrips aurantii comprising the
application of
Emamectin-benzoate to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to a line of the table C.

Table 164: A method of controlling representatives of the genus Aceria
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 165: A method of controlling representatives of the genus Aculus
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 166: A method of controlling representatives of the genus Brevipalpus
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 167: A method of controlling representatives of the genus Panonychus
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 168: A method of controlling representatives of the genus Phyllocoptruta
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.


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Table 169: A method of controlling representatives of the genus Tetranychus
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 170: A method of controlling representatives of the genus Heterodera
comprising the
application of Emamectin-benzoate to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 171: A method of controlling representatives of the genus Meloidogyne
comprising
the application of Emamectin-benzoate to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 172: A method of controlling representatives of the genus Adoxophyes
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 173: A method of controlling representatives of the genus Agrotis
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 174: A method of controlling Alabama argillaceae comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 175: A method of controlling Anticarsia gemmatalis comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 176: A method of controlling representatives of the genus Chilo
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination


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of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 177: A method of controlling Clysia ambiguella comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 178: A method of controlling Crocidolomia binotalis comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 179: A method of controlling representatives of the genus Cydia
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 180: A method of controlling Diparopsis castanea comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 181: A method of controlling representatives of the genus Earias
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 182: A method of controlling representatives of the genus Ephestia
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 183: A method of controlling representatives of the genus Heliothis of
Spinosad to a
herbicidally resistant transgenic crop, wherein the combination of the active
principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.


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Table 184: A method of controlling Hellula undalis comprising the application
of Spinosad to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 185: A method of controlling Keiferia lycopersicella comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 186: A method of controlling Leucoptera scitella comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 187: A method of controlling representatives of the genus Lithocollethis
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 188: A method of controlling Lobesia botrana comprising the application
of Spinosad
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 189: A method of controlling Ostrinia nubilalis comprising the
application of Spinosad
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 190: A method of controlling representatives of the genus Pandemis
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 191: A method of controlling Pectinophora gossypiella comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active


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principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 192: A method of controlling Phyllocnistis citrelia comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 193: A method of controlling representatives of the genus Pieris
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 194: A method of controlling Plutella xylostella comprising the
application of Spinosad
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 195: A method of controlling representatives of the genus Scirpophaga
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 196: A method of controlling representatives of the genus Sesamia
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 197: A method of controlling representatives of the genus Sparganothis
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 198: A method of controlling representatives of the genus Spodoptera
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.


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Table 199: A method of controlling representatives of the genus Tortrix
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 200: A method of controlling Trichoplusia ni comprising the application
of Spinosad to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.

Table 201: A method of controlling representatives of the genus Agriotes
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 202: A method of controlling Anthonomus grandis comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 203: A method of controlling representatives of the genus Curculio
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 204: A method of controlling Diabrotica balteata comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.

Table 205: A method of controlling representatives of the genus Leptinotarsa
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 206: A method of controlling representatives of the genus Lissorhoptrus
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 207: A method of controlling representatives of the genus Otiorhynchus
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 208: A method of controlling representatives of the genus Aleurothrixus
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 209: A method of controlling representatives of the genus Aleyrodes
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 210: A method of controlling representatives of the genus Aonidiella
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 211: A method of controlling representatives of the family Aphididae
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 212: A method of controlling representatives of the genus Aphis
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 213: A method of controlling Bemisia tabaci comprising the application
of Spinosad to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to a line of the table C.


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Table 214: A method of controlling representatives of the genus Empoasca
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 215: A method of controlling representatives of the genus Mycus
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 216: A method of controlling representatives of the genus Nephotettix
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 217: A method of controlling representatives of the genus Nilaparvata
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 218: A method of controlling representatives of the genus Pseudococcus
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 219: A method of controlling representatives of the genus Psylla
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 220: A method of controlling representatives of the genus
Quadraspidiotus
comprising the application of Spinosad to a herbicidally resistant transgenic
crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to a line of the table C.

Table 221: A method of controlling representatives of the genus Schizaphis
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination


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of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 222: A method of controlling representatives of the genus Trialeurodes
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 223: A method of controlling representatives of the genus Lyriomyza
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 224: A method of controlling representatives of the genus Oscinella
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 225: A method of controlling representatives of the genus Phorbia
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 226: A method of controlling representatives of the genus Frankliniella
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 227: A method of controlling representatives of the genus Thrips
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 228: A method of controlling Scirtothrips aurantii comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.


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Table 229: A method of controlling representatives of the genus Aceria
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 230: A method of controlling representatives of the genus Aculus
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 231: A method of controlling representatives of the genus Brevipalpus
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 232: A method of controlling representatives of the genus Panonychus
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 233: A method of controlling representatives of the genus Phyllocoptruta
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 234: A method of controlling representatives of the genus Tetranychus
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 235: A method of controlling representatives of the genus Heterodera
comprising the
application of Spinosad to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to a line of the table C.

Table 236: A method of controlling representatives of the genus Meloidogyne
comprising
the application of Spinosad to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to a line of the table C.

Table 237: A method of controlling Mamestra brassica comprising the
application of
Spinosad to a herbicidally resistant transgenic crop, wherein the combination
of the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to a line of the table C.
Example B1: Action against Anthonomus grandis adults Spodoptera fittoralis or
Heliothis
virescens
Young transgenic cotton plants which express the S-endotoxin CryIIIA are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of emamectin-
benzoate
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising emamectin-
benzoate
and conventional CryIIIA-toxin at a concentration of in each case 100, 50, 10,
5, 1 ppm
respectively..

In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Exam Ike B2: Action against Anthonomus arrandis adults SpodQptera littoralis
or Heliothis
virescens
Young transgenic cotton plants which express the S-endotoxin CryIIIA are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of abamectin
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants


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WO 99/33343 PCT/EP98/08384
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which have been treated with an emulsion spray mixture comprising abamectin
and conven-
tional CryIlIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm
respectively.

In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Example B3: Action against Anthonomus grandis adults. Spodoptera littoralis or
Heliothis
virescens
Young transgenic cotton plants which express the 8-endotoxin CryIlIA are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of spinosad
respectively.
After the spray coating has dried on, the cotton plants are populated with 10
adult
Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens
larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising spinosad and
conven-
tional CryillA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm
respectively.

In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Example B4: Action against Anthonomus grandis adults Spodoptera littoralis or
Heliothis
virescens
Young transgenic cotton plants which express the &-endotoxin Cryla(c) are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of spinosad
respectively.
After the spray coating has dried on, the cotton plants are populated with 10
adult
Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens
larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising spinosad and
conven-
tional CryIlIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm
respectively.

In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.


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Example B5: Action against Anthonomus grandis adults. Spodoptera littoralis or
Heliothis
virescens
Young transgenic cotton plants which express the 8-endotoxin Cryla(c) are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of abamectin
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising abamectin
and conven-
tional CrylIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm
respectively.

In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Example B6: Action against Anthonomus grandis adults. S oddoatera littoralis
or Heliothis
virescens
Young transgenic cotton plants which express the 8-endotoxin Cryla(c) are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of emamectin
benzoate
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising emamectin
benzoate
and conventional CrylIIA-toxin at a concentration of in each case 100, 50, 10,
5, 1 ppm
respectively.

In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Example B7: Action against Ostrinia nubilalis Spodoptera spp or Heliothis soo

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the
same size
which is planted with conventional maize, both showing natural infestation
with Ostrinia


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nubilalis. Spodoptera sp or Heliothis, are sprayed with an aqueous emulsion
spray mixture
comprising 200, 100, 50, 10, 5, 1 ppm of spinosad. Immediately afterwards,
plot (b) is
treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm
of the
endotoxin expressed by KnockOut . Evaluation takes place 6 days later. The
percentage
reduction in population (% action) is determined by comparing the number of
dead pests on
the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis. Spodoptera sgor Heljothis is observed
on the plants
of plot (a), while plot (b) shows a control level of not over 80%.

Example B8: Action against Ostrinia nubilalis. S oddootera sn or Heliothis sp

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the
same size
which is planted with conventional maize, both showing natural infestation
with Ostrinia
nubilalis. Spodoptera sp or Heljothis, are sprayed with an aqueous emulsion
spray mixture
comprising 200, 100, 50, 10, 5, 1 ppm of abamectin. Immediately afterwards,
plot (b) is
treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm
of the
endotoxin expressed by KnockOut . Evaluation takes place 6 days later. The
percentage
reduction in population (% action) is determined by comparing the number of
dead pests on
the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis. Spodo tp era sp or Heliothis is
observed on the plants
of plot (a), while plot (b) shows a control level of not over 80%.

Example B9: Action against Ostrinia nubilalis. S odootera sp or Heliothis sn

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the
same size
which is planted with conventional maize, both showing natural infestation
with O t inia
nubilalis. Spodoptera S2 or Heljothis, are sprayed with an aqueous emulsion
spray mixture
comprising 200, 100, 50, 10, 5, 1 ppm of emamectin benzoate. Immediately
afterwards, plot
(b) is treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5,
1 ppm of the
endotoxin expressed by KnockOut . Evaluation takes place 6 days later. The
percentage
reduction in population (% action) is determined by comparing the number of
dead pests on
the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis. Spodoptera sg or Heliothis is observed
on the plants
of plot (a), while plot (b) shows a control level of not over 80%.


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The invention further relates to

(B) A method of protecting plant propagation material and plant organs formed
at a later
point in time from attack by pests, characterized in that

a pesticide comprising, as pesticidally active compound, at least one
macrolide compound,
especially abamectin, emamectin or spinosad in free form or in agrochemically
utilizable salt
form as active ingredient and at least one auxiliary in close spatial
proximity to, or spatially
together with, planting or applying the propagation material is employed to
the site of
planting or sowing;

the corresponding use of these compounds, corresponding pesticides whose
active
ingredient is selected from amongst these compounds, a method of producing and
using
these compositions, and plant propagation material thus protected against
attack by pests.
The macrolides used according to the invention are known to those skilled in
the art. They
are the classes of substances as mentioned under invention part (A). Abamectin
and
emamectin are preferred.

Agrochemically utilizable salts of the macrolides according to the invention
are, for example,
the same as under invention part (A).

In the case of abamectin, the free form is preferred in the frame of invention
part (B). Espe-
cially preferred within the scope of the invention part (B) is a method in
which emamectin is
employed in free form or as agrochemically acceptable salt; especially as
salt; in particular
as the benzoate, substituted benzoate, benzenesulphonate, citrate, phosphate,
tartrate or
maleate; preferably as the benzoate or benzenesulphonate, especially
preferably as the
benzoate.

The scope of the subject-matter of the invention (B) extends in particular to
representatives
of the classes Insecta, Arachnida and Nematoda.

These are mainly insects of the order Lepidoptera, for example
Acleris spp., Adoxophyes spp., Aegeria spp., Agrotis spp., Alabama
argillaceae, Amylois
spp., Anticarsia gemmatalis, Archips spp., Argyrotaenia spp., Astylus
atromaculatus,
Autographa spp., Busseola tusca, Cadra cautella, Carposina nipponensis, Chilo
spp.,
Choristoneura spp., Clysia ambiguella, Cnaphalocrocis spp., Cnephasia spp.,
Cochylis spp.,


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Coleophora spp., Crocidolomia binotalis, Cryptophlebia leucotreta, Cydia spp.,
Diatraea
spp., Diparopsis castanea, Earias spp., Ephestia spp., Eucosma spp.,
Eupoecilia
ambiguella, Euproctis spp., Euxoa spp., Grapholita spp., Hedya nubiferana,
Heliothis spp.,
Hellula undalis, Heteronychus arator, Hyphantria cunea, Keiferia
lycopersicella, Leucoptera
scitella, Lithocollethis spp., Lobesia botrana, Lymantria spp., Lyonetia spp.,
Malacosoma
spp., Mamestra brassicae, Manduca sexta, Operophtera spp., Ostrinia nubilalis,
Pammene
spp., Pandemis spp., Panolis flammea, Pectinophora gossypiella, Phthorimaea
operculella,
Pieris rapae, Pieris spp., Plutella xylostella, Prays spp., Scirpophaga spp.,
Sesamia spp.,
Sparganothis spp., Spodoptera spp., Synanthedon spp., Thaumetopoea spp.,
Tortrix spp.,
Trichoplusia ni and Yponomeuta spp.;
of the order Coleoptera, for example
Agriotes spp., Anthonomus spp., Atomaria linearis, Chaetocnema tibialis,
Cosmopolites
spp., Curculio spp., Dermestes spp., Diabrotica spp., Epilachna spp., Eremnus
spp.,
Leptinotarsa decemlineata, Lissorhoptrus spp., Melolontha spp., Orycaephilus
spp.,
Otiorhynchus spp., Phlyctinus spp., Popillia spp., Psylliodes spp.,
Rhizopertha spp.,
Scarabeidae, Sitophilus spp., Sitotroga spp., Tenebrio spp., Tribolium spp.
and Trogoderma
spp.;
of the order Orthoptera, for example
Blatta spp., Blattella spp., Gryllotalpa spp., Leucophaea maderae, Locusta
spp., Periplaneta
spp. and Schistocerca spp.;
of the order Psocoptera, for example Liposcelis spp.;
of the order Anoplura, for example
Haematopinus spp., Linognathus spp., Pediculus spp., Pemphigus spp. and
Phylloxera
spp.;
of the order Mallophaga, for example Damalinea spp. and Trichodectes spp.;
of the order Thysanoptera, for example Frankliniella spp., Hercinothrips spp.,
Taeniothrips
spp., Thrips palmi, Thrips tabaci and Scirtothrips aurantii;
of the order Heteroptera, for example Cimex spp., Distantiella theobroma,
Dysdercus spp.,
Euchistus spp. Eurygaster spp. Leptocorisa spp., Nezara spp., Piesma spp.,
Rhodnius spp.,
Sahlbergella singularis, Scotinophara spp. and Triatoma spp.;
of the order Homoptera, for example Aleurothrixus floccosus, Aleyrodes
brassicae,
Aonidiella spp., Aphididae, Aphis spp., Aspidiotus spp., Bemisia tabaci,
Ceroplaster spp.,
Chrysomphalus aonidium, Chrysomphalus dictyospermi, Coccus hesperidum,
Empoasca
spp., Eriosoma larigerum, Erythroneura spp., Gascardia spp., Laodelphax spp.,
Lecanium


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WO 99/33343 PCT/EP98/08384
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comi, Lepidosaphes spp., Macrosiphus spp., Myzus spp., Nephotettix spp.,
Nilaparvata
spp., Paratoria spp., Pemphigus spp., Planococcus spp., Pseudaulacaspis spp.,
Pseudococcus spp., Psylla spp., Puivinaria aethiopica, Quadraspidiotus spp.,
Rhopalosiphum spp., Saissetia spp., Scaphoideus spp., Schizaphis spp.,
Sitobion spp.,
Trialeurodes vaporariorum, Tnoza erytreae and Unaspis citri;
of the order Hymenoptera, for example Acromyrmex, Atta spp., Cephus spp.,
Diprion spp.,
Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium
pharaonis,
Neodiprion spp., Sotenopsis spp. and Vespa spp.;
of the order Diptera, for example Aedes spp., Antherigona soccata, Bibio
hortulanus,
Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp.,
Cuterebra spp.,
Dacus spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Glossina
spp.,
Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza
spp.,
Musca spp., Oestrus spp., Orseolia spp., Oscinella frit, Pegomyia hyoscyami,
Phorbia spp.,
Rhagoletis pomonella, Sciara spp., Stomoxys spp., Tabanus spp., Tannic spp.
and Tipula
spp=;
of the order Siphonaptera, for example Ceratophyllus spp. and Xenopsylla
cheopis; or
of the order Thysanura, for example Lepisma saccharina.

Amongst the class Arachnida, they are preferably representatives of the order
Acanna, for
example
Acarus siro, Acena sheldoni, Aculus schlechtendali, Amblyomma spp., Argas
spp.,
Boophilus spp., Brevipalpus spp., Bryobia praetiosa, Calipitrimerus spp.,
Chorioptes spp.,
Dermanyssus gallinae, Eotetranychus carpini, Eriophyes spp., Hyalomma spp.,
Ixodes spp.,
Olygonychus pratensis, Omithodoros spp., Panonychus spp., Phyliocoptruta
oleivora,
Polyphagotarsonemus latus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus
spp.,
Sarcoptes spp., Tarsonemus spp. and Tetranychus spp..

Especially preferred is the control of insects of the orders Coleoptera and
Lepidoptera;

in the order Colepotera especially the genera and species Agriotes spp.,
Anthonomus spp.,
Atomaria linearis, Chaetocnema tibialis, Diabrotica spp. and Leptinotarsa
decemlineata;

in the order Lepidoptera the genera and species Adoxophyes spp., Agrotis spp.,
Alabama
argillaceae, Anticarsia gemmatalis, Chilo spp., Cydia spp., Ephestia spp.,
Heliothis spp.,
Keiferia lycopersicella, Mamestra brassicae, Pectinophora gossypiella,
Plutella xylostella,
Sesamia spp., Spodoptera spp., Tortrix spp., and Trichoplusia.


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A further preferred subject according to the invention part (B) is the control
of repre-
sentatives of the class Nematoda, such as root knot nematodes, stem eelworms
and foliar
nematodes;
especially Heterodera spp., for example Heterodera schachtii, Heterodora
avenae and
Heterodora trifolii; Globodera spp., for example Globodera rostochiensis;
Meloidogyne spp.,
for example Meloidogyne incoginita and Meloidogyne javanica; Radopholus spp.,
for
example Radopholus similis; Pratylenchus, for example Pratylenchus neglectans
and
Pratylenchus penetrans; Tylenchulus, for example Tylenchulus semipenetrans;
Longidorus,
Trichodorus, Xiphinema, Ditylenchus, Aphelenchoides and Anguina,
in particular Meloidogyne, for example Meloidogyne incognita, and Heterodera,
for example
Heterodera glycines.

The macrolides used according to the invention (B) are preventatively and/or
curatively
valuable active ingredients in the fields of insect control, even at low
application rates, while
being well tolerated by warm-blooded species, fish, beneficials and plants.
The active
ingredients used according to the invention are effective against all or
individual
development stages of normally sensitive, but also resistant, pests. The
action of the active
ingredients used according to the invention may become apparent directly, i.e.
in the form
of destruction of the pests, which occurs immediately or only after some time
has elapsed,
for example during ecdysis, or indirectly, for example as a reduced
oviposition and/or
hatching rate, the good action corresponding to a destruction rate (mortality)
of at least 50
to 60%.

With the aid of the active ingredients used in accordance with the invention
part (B), it is
possible to control, i.e. contain or destroy, pests which occur on plant
propagation material,
mainly on propagation material of useful plants and ornamentals in
agriculture, in
horticulture and in forests, and even plant organs which grow at a later point
in time are still
protected from these pests, that is to say the protection lasts, for example,
until resistant
mature plants have developed, and where the propagation material, or the
plants
developing therefrom, are protected not only from pests which attack the
aerial plant
organs, but also from soil-dwelling pests.

Suitable plant propagation material in the invention part (B), that is, for
example, seedlings,
rhizomes, nursery plants, cuttings or, in particular seed (seeds), such as
fruit, tubers,
kernels or bulbs, are, in particular, propagation material of cereals, such as
wheat, barley,
rye, oats, rice, maize or sorghum; beet, such as sugar or fodder beet; fruit,
for example


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pome fruit, stone fruit and soft fruit, for example apples, pears, plums,
peaches, almonds,
cherries or berries, for example strawberries, raspberries and blackberries;
legumes, such
as beans, lentils, peas or soya beans, oil crops, such as oilseed rape,
mustard, poppies,
olives, sunflowers, coconut, castor-oil plants, cacao or peanuts; cucurbits,
such as
pumpkins, cucumbers or melons; fibre plants, such as cotton, flax, hemp or
jute; citrus fruit,
such as oranges, lemons, grapefruit or mandarins; vegetables, such as spinach,
lettuce,
asparagus, cabbage species, carrots, onions, tomatoes, potatoes or capsicums;
Lauraceae,
such as avocado, Cinnamonium or camphor; or tobacco, nuts, coffee, egg plants,
sugar
cane, tea, pepper, grapevines, hops, Musaceae, latex plants or ornamentals;

especially of cereals, rice, cotton, maize, soya beans, oilseed rape,
vegetables, potatoes,
sunflowers, sugar beet and sorghum.

The genetically modified propagation material is preferably propagation
material, in
particular seed, which contains one or more genes expressing a pesticidal
resistance, in
particular an insecticidal or acaricidal, but also a fungicidal or
nematocidal, resistance,
which make the plant resistant to herbicides, which lead to increased
resistance to plant
diseases or which introduce other agronomically advantageous properties into
the plant.
Such plants, or their propagation material, are in particular those which
contain a gene
derived from a Bacillus thuringiensis and which encode an insecticidally
active protein or
contain a gene. These are, especially, genetically modified plant propagation
materials of
potatoes, alfalfa, cereals, such as wheat, barley, rye, oats, rice, maize or
sorghum;
legumes, such as beans, lentils, peas or soya beans; beet such as sugar or
fodder beet; oil
crops, such as oilseed rape, mustard, poppies, olives, sunflowers, coconut,
castor-oil plant,
cacao or peanuts; cucurbits, such as pumpkins, cucumbers or melons; fibre
plants, such as
cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruit
or mandarins;
vegetables, such as spinach, lettuce, asparagus, cabbage species, carrots,
onions or
tomatoes.

Examples of the genetically modified plant propagation material mentioned are,
for
example, the commercially available products Maximizer' (Knockout'),
Yieldgard',
Roundup Ready Soybeans', TC Blend' or NuCOTN 33B', all of which are known to
those
skilled in the art.


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Other fields of application for the active ingredients used in accordance with
the invention
part (B) are, for example, the protection of stored products or stores or in
the hygiene
sector; in particular the protection of domestic animals or productive
livestock from pests.
The invention of subject-matter (B) therefore also relates to corresponding
pesticides for
use, to be selected depending on the intended aims and the prevailing
circumstances, such
as emulsifiable concentrates, suspension concentrates, directly sprayable or
dilutable
solutions, spreadable pastes, dilute emulsions, sprayable powders, soluble
powders,
dispersible powders, wettable powders, dusts, granules or encapsulations in
polymeric
substances which comprise - at least - one of the active ingredients used in
accordance
with the invention, and to the use of these insecticidal compositions for use
in a method.
Preferred is a composition which comprises only one macrolide compound,
especially
emamectin or a salt thereof.

In these compositions, the active ingredient is employed in pure form, for
example a solid
active ingredient in a particular particle size or, preferably, together with -
at least - one of
the auxiliaries conventionally used in the art of formulation, such as
extenders, for example
solvents or solid carriers, or such as surface-active compounds (surfactants).

Suitable auxiliaries such as solvents, solid carriers, surface-active
compounds, non-ionic
surfactants, cationic surfactants and anionic surfactants in the compositions
employed in
accordance with the invention are, for example, those which have been
described in
EP-A-736 252.

Liquid formulations for the treatment of plant propagation material according
to invention
part (B), especially of seed, comprise, for example,
surface-active substances (1 - 15% by weight), such as ethoxylated
tristyrenephenols and
their salts, alkyl polyglycol ether ethoxylates,
polyoxypropylene/polyoxyethylene
copolymers, the sodium salt of lignosulphonic acid, salts of
polynaphthalenesulphonic acid
and alkylbenzenesulphonic acid triethanolamine salt;
antifreeze agents (5 - 15%), such as, for example, DL-propane-1,2-diol or
propane-1,2,3-
triol;
colourants (1 - 10%), such as pigments or water-soluble dyes;
antifoams (0.05 -1 %), such as polydimethylsiloxane;
coatings (1 - 10%), such as polyethylene glycol, polyvinyl acetate,.
polyvinylpyrrolidone,
polyacrylate;


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preservatives (0.1 - I%), such as 1,2-benzoisothiazol-3-one;
thickeners (0.1 - 1 %), such as heteropolysaccharide; and
solvents, such as water.

Solid formulations for the treatment of plant propagation material, especially
of seed,
comprise, for example:
surface-active substances (1- 10%), such as alkyl polyglycol ether ethoxylate,
polyoxypropylene/polyoxyethylene copolymers, the sodium salt of lignosulphonic
acid, salts
of polynaphthalenesulphonic acid;
colourants (1 - 10%), such as pigments or water-soluble dyes;
antifoams (0.05 - 1 %), such as polydimethylsiloxane;
coatings (1 - 10%), such as polyethylene glycol or cellulose; and
carriers (to 100% w/w), such as silica powder, talc powder, clays and the
like.

As a rule, the compositions comprise 0.1 to 99%, in particular 0.1 to 95%, of
active
ingredient and 1 to 99.9%, in particular 5 to 99.9%, of - at least - one solid
or liquid auxiliary,
it being possible, as a rule, for 0 to 25%, in particular 0.1 to 20%, of the
compositions to be
surfactants (% is in each case per cent by weight). While concentrated
compositions are
more preferred as commercially available goods, the end consumer will use, as
a rule, dilute
compositions having much lower concentrations of active ingredient.

Preferred compositions, such as emulsifiable concentrations, dusts, suspension
concentrates, wettable powders and granules have, for example, those
compositions which
are mentioned in EP-A-736 252.

The compositions according to the invention part (B) can also comprise other
solid or liquid
auxiliaries, such as stabilizers, for example unepoxidized or epoxidized
vegetable oils (for
example epoxidized coconut oil, rapeseed oil or soya oil), antifoams, for
example silicone
oil, preservatives, viscosity regulators, binders and/or tackifiers, and also
fertilizers or other
active ingredients for achieving specific effects, for example bactericides,
nematicides,
molluscides or selective herbicides.

The action of the compositions according to the invention part (B) can be
broadened
considerably by adding other, for example insecticidally, acaricidally and/or
fungicidally
active, ingredients and adapted to prevailing circumstances. Suitable
additions of
insecticidally and acaricidally active ingredients are, for example,
representatives of the
following classes of active ingredients: organophosphorus compounds,
nitrophenols and


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derivatives, formamidines, triazine derivatives, nitroenamine derivatives,
nitro- and
cyanoguanidine derivatives, ureas, benzoylureas, carbamates, pyrethroids,
chlorinated
hydrocarbons and Bacillus thuringiensis products. Especially preferred
components in
mixtures are N1-25, TI-304, TI-435, MTI-446, fipronil, lufenuron,
pyripfoxyfen, thiacloprid,
fluxofenime; imidacloprid, thiamethoxam, fenoxycarb, diafenthiuron,
pymetrozine, diazinon,
disulphoton; profenofos, furathiocarb, cyromazin, cypermethrin, tau-
fluvalinate, tefluthrin or
Baciiius thuringiensis products, very especially NI-25, TI-304, TI-435, MTI-
446, fipronil,
thiacloprid, imidacloprid, thiamethoxam and tefluthrin.

Examples of suitable additions of fungicidally active ingredients are the
following
compounds: azoxystrobin; bitertanol; carboxin; Cu20; cymoxanil; cyproconazole;
cyprodinil;
dichlofluamid; difenoconazole; diniconazole; epoxiconazole; fenpiclonil;
fludioxonil;
fluquiconazole; flusilazole; flutriafol; furalaxyl; guazatin; hexaconazole;
hymexazol; imazalil;
imibenconazole; ipconazole; kresoxim-methyl; mancozeb; metalaxyl; R-metalaxyl;
metconazole; oxadixyl, pefurazoate; penconazole; pencycuron; prochloraz;
propiconazole;
pyroquilone; SSF-109; spiroxamin; tebuconazole; teflutrin; thiabendazole;
tolifluamide;
triazoxide; triadimefon; triadimenol; triflumizole; triticonazole and
uniconazole.

The compositions to be used according to the invention part (B) are prepared
in a known
manner, for example in the absence of auxiliaries by grinding and/or
screening, for example
to a particular particle size, or by compressing a solid active ingredient,
and in the presence
of at least one auxiliary, for example by intimately mixing and/or grinding
the active
ingredient with the auxiliary/auxiliaries. These methods for preparing the
compositions
according to the invention and the use of macrolides for preparing these
compositions are
also subjects of the invention.

The application methods according to the invention part (B) for the protection
of plant
propagation material, which, in accordance with the invention, is any plant
material capable
of developing complete plants after planting or sowing to the site of planting
or sowing, for
example seedlings, rhizomes, nursery plants, cuttings or, in particular, seed
(seeds), such
as fruits, tubers, kernels or bulbs, against attack by pests are characterized
in that, for
example, suitable compositions are applied in such a manner that they are
applied in close
spatial proximity to, or spatially together with, planting or sowing the
propagation material to
the site of planting or sowing. Application of these compositions in close
spatial proximity to
planting or sowing the propagation material to the site of planting or sowing
takes place in
accordance with the invention, preferably prior to planting or sowing the
propagation


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material, by applying the compositions by soil application directly to the
site where the
propagation material has been planted or sown, for example preferably prior to
sowing into
the seed furrow or to a closely delimited area around the site of planting or
sowing the
propagation material. Application of such compositions, which takes place
spatially together
with planting or applying the propagation material to the site of planting or
sowing is to be
understood as meaning that propagation material which has been pretreated with
these
compositions is planted or sown at the site of planting or sowing, it being
possible,
depending on the intended aims and prevailing circumstances, for the
pretreatment of the
propagation material to be effected for example by spraying, atomizing,
dusting or
scattering the compositions over the propagation material or brushing or
pouring the
compositions over the propagation material or, in the event of seed, in
particular also by
dressing the seed. When carrying out seed dressing, which is preferred
according to the
invention, i.e. dry seed, wet seed-dressing, liquid seed-dressing or slurry
dressing, a
suitable pesticide is added to the seed prior to sowing in a seed-dressing
apparatus and the
composition is distributed uniformly over the seed, for example by stirring
the contents of
the seed-dressing apparatus and/or by rotating and/or shaking the entire seed-
dressing
apparatus. Particular embodiments of such a seed-dressing treatment comprise,
for
example, immersing the seed in a liquid composition, coating the seed with a
solid
composition (seed coating) or by achieving penetration of the active
ingredient into the seed
by adding the composition to the water used for pre-soaking the seed (seed
soaking).
Typical application rates for the compositions used in the seed-dressing
treatment
according to the invention are, for example, between 0.1 and 100 g of active
ingredient per
100 kg of seed, in particular between 1 and 60 g / 100 kg of seed, preferably
between 4
and 40g / 100 kg of seed.

The seed-dressing treatment according to invention part (B) comprises, in
particular, that
due to the low toxicity of the active ingredient used, good tolerance by birds
of the dressed
seed is observed, for example, in the case of birds which, being seed-eaters
in the open
countryside, tend to take seed from freshly seeded fields, such as buntings,
blackbirds,
thrushes, ducks, pheasants, finches, geese, linnets, chickens, crows,
skylarks, tits,
seagulls, ravens, partridges, wood pigeons, goldf inches, pigeons or siskins.
The seed-
dressing treatment according to the invention also extends to the dressing of
stored seed.
The commercial plant propagation material which has been pretreated according
to
invention part (B) is another subject of the invention.


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Examples of formulations of macrolide compounds which can be used in the
method
according to the invention (B), that is to say solutions, granules, dusts,
sprayable powders,
emulsion concentrates, coated granules and suspension concentrates, are of the
type as
has been described in, for example, EP-A-580 553, Examples F1 to F10.

Example 171: General procedure for liquid seed dressing

The required amount of liquid formulation is placed into an Erlenmeyer flask.
The flask is
shaken to distribute the liquid on the entire bottom of the vessel. The
required amount of
seed is introduced into the flask immediately thereafter. The flask is shaken
vigorously by
hand for approximately one minute so that all the seed is covered with liquid.
The contents
of the flask are turned out onto a drying rack and dried in an oven.

Example F2: General procedure for dry seed dressing

Various wide-necked flasks are each filled with the same number of seed
kernels, and each
flask is charged with such an amount of wettable powder that the desired
amount of active
ingredient per seed kernel (for example 0.03, 0.1 or 0.3 mg per kernel) is
obtained. The
flasks are placed on a roller and rotated for three minutes at 80
rotations/minute. The seed
kernels which are attached to the walls of the flasks are then disengaged by
shaking by
hand, and the flasks are rotated in the opposite direction for three minutes.

Biological exam les (% = per cent by weight, unless otherwise specified)

Example B4: Seed-dressing action against first-instar larvae of Spodoptera
littoralis on
maize leaves

Maize seeds which have been dressed as described in procedure F1 are sown. 12,
19, 26,
33, 40 and 47 days after sowing, sections 5 to 8 cm in length of the top-most
leaves of the
plants are placed in glass beakers and infested with a predetermined quantity
of a
suspension of freshly hatched L1 larvae of Spodoptera littoralis. The beakers
are closed
with a lid and kept at 25 C, a relative atmospheric humidity of 60% and a day-
light cycle of
16 hours. Evaluation takes place three to five days after infestation. The
percentage
reduction in population (% action) is determined by comparing the number of
surviving
larvae on the plants grown from dressed seeds and from untreated seeds.

EX-ample B5: Seed-dressing action ction against adult Diabrotica balteata on
sugar beet leaves
Seeds of sugar beet which have been dressed as described in procedure F1 are
sown. 33,
40, 47, 54 and 61 days after sowing, the leaves of in each case three to 5
plants are placed


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in a glass beaker and infested with a predetermined number of young adult
Diabrotica
balteata. The beakers are closed with a lid and kept at 25 C, a relative
atmospheric
humidity of 60% and 16 hours of daylight. Evaluation takes place three to five
days after
infestation. The percentage reduction in population (% action) is determined
by comparing
the number of surviving Diabrotica adults on the plants grown from dressed
seeds and from
untreated seeds.

Example B6: Seed-dressing action against third-instar larvae of Diabrotica
balteata on
maize roots
Maize seeds which have been treated as described in procedure F1 are sown. 14,
21 and
28 days after sowing, in each case five third-instar larvae of Diabrotica
balteata are placed
on the bottom of each plant pot. Evaluation takes place 6 days after
infestation. The data
registered are the number of surviving instars (larvae and pupae) in the stem
of the plants,
on the soil surface and in the soil. The percentage reduction in population (%
action) is
determined by comparing the number of surviving larvae and pupae on the plants
grown
from dressed seeds and from untreated seeds and their environment.

Example B7: Seed-dressing action against Aphis fabae

A glass flask or a plastic container is filled with 100 g of bean seeds and
such an amount of
a formulation of the active ingredient that a ratio of 0.1, 1 or 10 g of
active ingredient per kg
of seed is achieved. The active ingredient is distributed uniformly on the
seed surface by
rotating and/or shaking the container. The seeds which have been dressed in
this way are
sown in flowerpots (3 seeds per pot). The plantlets are grown in a greenhouse
at 25 to 30 C
until they have reached the 2-leaf stage and then populated with Aphis fabae.
6 days after
population, the test is evaluated. The percentage reduction in population (%
action) is
determined by comparing the number of surviving individuals on the plants
grown from
dressed seeds and from untreated seeds.

In this test, a good action is shown by abamectin, emamectin and spinosad.
Exam In a B8: Seed-dressing action against Mvzus nersicae

A glass flask or a plastic container is filled with 100 g of sugar beet seeds
and such an
amount of a pasty formulation of the active ingredient, prepared with a
sprayable powder
and a little water, that a ratio of 0.1, 1 or 10 g of active ingredient per kg
of seed is
achieved. The closed seed-dressing container is agitated on a roller until the
paste is
distributed uniformly on the seed surface. The seeds which have been dressed
(coated) in


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this way are dried and sown into loess soil in plastic pots. The seedlings are
grown in a
greenhouse at 24 to 26 C, a relative atmospheric humidity of 50 to 60% and a
daily
illumination time of 14 hours. 4 weeks after germination, the plants, which
are 10 cm high,
are populated with a mixed population of Myzus persicae. Evaluation takes
place 2 and 7
days after the plants have been populated. The percentage reduction in
population (%
action) is determined by comparing the number of surviving individuals on the
plants grown
from dressed seeds and from untreated seeds.

In this test, a good action is shown by abamectin, emamectin and spinosad.
The invention further relates to

(C) A method of controlling wood pests and molluscs, characterized in that

a pesticidally active amount of a pesticide comprising, as pesticidally active
compound, at
least one macrolide, preferably abamectin, emamectin or spinosad, in free form
or
agrochemically utilizable salt form, as active ingredient and at least one
auxiliary is applied
to the pests or their environment;

to the corresponding use of these compounds, to corresponding pesticides whose
active
ingredient is selected from amongst these compounds, to a process for the
preparation of
and to the use of these compositions, and to plant propagation material thus
protected from
attack by pests.

The macrolides used in accordance with the invention are the same as mentioned
under the
aspect (A) of the invention. Also the salt are as mentioned under invention
part (A). In the
case of abamectin, the free form is preferred in accordance with the
invention. Especially
preferred for the purposes of the present invention is a composition which
comprises
emamectin in free form or as an agrochemically tolerated salt as the only
pesticidally active
component; especially as the salt; more especially as the benzoate,
substituted benzoate,
benzenesulphonate, citrate, phosphate, tartrate or maleate; preferably as the
benzoate or
benzenesulphonate, especially preferably as the benzoate.

A larger number of. different classes of active ingredient are mentioned in
the literature as
arthropodecidally acting active ingredients for controlling gastropods and
termites.
Surprisingly, it has now been found that the compounds known under the
collective term


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macrolides, too, exhibit an important molluscicidal and termiticidal activity,
specifically
against gastropods, such as slugs and snails, and against wood pests, in
particular
representatives of the order of Isoptera.

The molluscs include, for example,
Ampullariidae; Arlon (A. ater, A. circumscriptus, A. hortensis, A. rufus);
Bradybaenidae
(Bradybaena fruticum); Cepaea (C. hortensis, C. Nemoralis); Cochlodina;
Deroceras (D.
agrestis, D. empiricorum, D. laeve, D. reticulatum); Discus (D. rotundatus);
Euomphalia;
Galba (G. trunculata); Helicella (H. itala, H. obvia); Helicidae (Helicigona
arbustorum);
Helicodiscus; Helix (H. aperta); Limax (L. cinereoniger, L. flavus, L.
marginatus, L. maximus,
L. tenellus); Lymnaea; Milax (M. gagates, M. marginatus, M. sowerbyi); Opeas;
Pomacea
(P. canaticulata); Vallonia and Zanitoides.

The termites include, in particular, the families Hodotermitidae,
Kalotermitidae, Rhino-
termitidae and Termitidae. Other pests which damage wood by feeding on wood,
using it as
a substrate or reproducing on wood, are to be understood as meaning, for
example, wood-
boring insects such as representatives of the family Lyctidae, the family
Apidae, for
example Xylocopa virginica, and of the family Anobiidae, such as Anobium
punctatum.
Slugs and snails as pests in horticulture and agriculture are a massively
increasing problem.
They can cause severe plant damage by feeding, and can also bring about
undesirable
soiling by slug and snail mucus and faeces. Novel changes in the management of
crops
have led to an increased number in varieties of plant species which are
sensitive to slugs
and snails, and the obligation to dispense with burning stubble fields - which
is based on an
ecological approach - and to plough in the straw instead suggests that the
existing mollusc
problems, especially slug problems, will be made worse.

Termites are capable of inflicting substantial damage to buildings in
particular at
geographical latitudes of between 42 N and 42 S . In principle, two types of
termites can
be distinguished:

Termites which live in the subsoil - the most widely distributed type -
require warm air and a
moist environment. In order always to have available the necessary moisture,
these termites
must have direct access to the moist soil. Damage caused by subterranean
termites is
virtually always associated with damage to wood.

Termites which use dry wood as their substrate represent - even though less
frequently - a
large problem since they do not require contact with the moist soil. They
penetrate into


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buildings underneath roof shingles, through gaps and through ventilation
holes. Others are
brought into households with items of furniture which are already infested.
Pretreatment of
the wood is considered the most efficient method of controlling such termites.
The damages
of termites living on dry wood are caused more slowly than damages of termites
living in a
moist environment, therefore, damage caused by termites of the first-mentioned
type is
found predominantly in old buildings.

Damage caused by termites living subterraneously in a humid environment can be
prevented by the application of insecticidally active substances to the
termites or their
environment. Such compounds are conventionally employed mainly for application
to the
soil around the buildings.

Gastropodicides which are currently commercially available comprise
metaldehyde and
carbamates such as, for example, methiocarb. Carbamates are highly effective
as
molluscicides, but exhibit the serious disadvantage of being highly toxic to
mammals such
as, for example, cats, dogs and hedgehogs, and other organisms such as, for
example,
earthworms, which should be left unharmed. While the metaldehyde molluscicides
exhibit a
lower toxicity, they are not lethal to molluscs but have an anaestheticizing
or dehydrating
effect, thus immobilizing the pests. There is therefore a demand for a useful
molluscicide
which is highly effective against, for example, slugs and snails, but has no,
or a very low,
toxic effect on beneficials such as, for example, earthworms, and mammals.
This object is
achieved with the macrolides of the present invention.

Also, the currently available compositions for controlling termites are not
satisfactory in all
respects since generally relatively large zones around building constructions,
or these
buildings themselves, must be treated with large amounts of insecticide. This
can lead to
secondary problems, in particular in the case of persistent pesticides,
especially in houses.
Here too, there is therefore a further demand for improved solutions, in
particular by
applying active ingredients which can be employed in particularly low
quantities and which
have low volatility.

The invention part (C) therefore also relates to pesticides such as
emulsifiable concen-
trates, suspension concentrates, directly sprayable or dilutable solutions,
spreadable
pastes, dilute emulsions, sprayable powders, soluble powders, dispersible
powders,
wettable powders, dusts, granules, pellets or encapsulations in polymeric
substances, all of


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which are to be chosen to suit the intended aims and the prevailing
circumstances and
which comprise - at least - one of the active ingredients according to the
invention.

The active ingredient is employed in these compositions in pure form, for
example a solid
active ingredient in a particular particle size, or, preferably, together with
- at least - one of
the auxiliaries or carriers conventionally used in formulation technology.

Examples of formulation auxiliaries are solid carriers, solvents, stabilizers,
slow-release
auxiliaries, colorants and, if appropriate, surface-active substances
(surfactants). Suitable
carriers and auxiliaries.are all substances conventionally used in crop
protection products,
in particular in gastropodicides. Suitable auxiliaries such as solvents, solid
carriers, surface-
active compounds, non-ionic surfactants, cationic surfactants, anionic
surfactants and other
auxiliaries in the compositions employed in accordance with the invention are,
for example,
those which have been described in EP-A-736'252.

Other suitable substances which can be used as carriers for molluscicides are
phago-
stimulants, that is to say the attractants and/or food (that is to say
substances which can be
utilized physiologically by slugs and snails) usually contained in slug and
snail bait
formulations. Mixtures of phagostimulants with other suitable organic and/or
inorganic
carriers may also be used.

Suitable phagostimulants for molluscicides are preferably: ground cereals,
such as, for
example, wheat flour, barley flour, rye flour, and also rice starch, crushed
soya beans, fish
meal, molasses, crushed rapeseed and the like. It is possible to employ either
only one
phagostimulant or else a mixture of phagostimulants.

To make the bait more palatable for the molluscs, one or more of the following
substances
can be used as additive for slug and snail baits:

a) a vitamin B, in particular B1, B2, nicotinic acid or nicotinamide;
b) vitamin E;

c) animal or vegetable proteinaceous material, for example albumins and their
hydrolytic
degradation products, in particular those obtained by enzymatic hydrolysis by,
for example,
pepsin, such as metaproteins, proteoses, peptones, polypeptides, peptides,
diketopipera-
zines and amino acids;

d) one or more amino acids or salts or amides thereof, which may also be
synthetic
products;


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e) a nucleic acid or a hydrolytic degradation product thereof, such as a
nucleotide, a
nucleoside, adenine, guanine, cytosine, uracile or thymine;

f) urea, carbamic acid;

g) an ammonium salt, for example ammonium acetate;

h) an amino sugar, for example, glucosamine or galactosamine;

i) compounds of sodium, potassium, calcium or magnesium, or traces of
compounds of
manganese, copper, iron, cobalt, zinc, aluminium, boron or molybdenum, in
particular
chelates of these, such as Versene';

j) phosphoric acid, or glyceryl or sugar phosphates;
k) water.

Stabilizers may be all known food stabilizers which have a fungistatic,
fungicidal,
bacteriostatic and/or bactericidal action, such as sodium benzoate, methyl p-
hydroxy-
benzoate, cetyltrimethylammonium bromide, citric acid, tartaric acid, sorbic
acid, phenols,
alkylphenols or chlorinated phenols.

Slow-release auxiliaries which may be employed include, in addition to the
substances
mentioned as solid carriers, resins such as urea/formaldehyde resins, soya-
bean meal,
waxes, stearates and oils such as castor oil.

Substances which can be employed as auxiliaries for molluscicides according to
part (C) of
the invention are, for example, binders such as methylcetlosolve,
polyvinylpyrrolidone,
polyvinyl alcohol, polyacrylates, polymethacrylates, natural waxes, chemically
modified
waxes and synthetic waxes, sugars, starch, alginates, agar, lignosulphonates
and gum
arabic, humectants such as potyalcohots, for example sugars or glycerol,
preservatives,
colorants, snail and slug attractants, repellents for warm-blooded species
and/or other
formulation auxiliaries. Combinations with known molluscicidally active
ingredients, for
example metaldehyde or mercaptodimethur, are also possible.

The formulation steps can be complemented by kneading, granulating (granules)
and, if
appropriate, compressing (pills, tablets, pellets).

The molluscicidal compositions which preferably comprise, other carriers
and/or auxiliaries
in addition to the active ingredient are preferably present in the ready-to-
use form as
sprayable powders, tracking powders, as granules (the active ingredient being
present as a


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mixture with the carrier material), or as pellets. Especially preferred
formulations are
tracking powders, granules or pellets.

Formulations which are specifically suitable for controlling molluscs
according to part (C) of
the invention are granules or pellets which comprise, as a rule, 0 to 90%,
preferably 0 to
70%, of carrier material, 0.1 to 10%, preferably 1 to 5%, of active
ingredient, 10 to 95%,
preferably 25 to 90%, of phagostimulant, 0.5 to 25%, preferably 5 to 20%, of
binder and, if
appropriate, 0 to 15% of other auxiliaries (% is in each case per cent by
weight).

The amount to be applied in each case as gastropodicide is not critical, due
to the lack of,
or low, toxicity to warm-blooded species and depends on the prevailing
circumstances, such
as severity of infestation, climatic conditions and the plants to be
protected. The application
rate of bait types according to the invention can be varied within a
substantial range. In
general, between 3 and 15 kg of snail and slug bait are used per hectare,
preferably
between 5 and 10 kg per hectare. Expediently, the gastropodicides are
distributed as
uniformly as possible between the crop plants by spraying an aqueous
suspension or by
spreading the powders, granules or pellets on the soil. If the plant canopy is
not dense, it
may also be expedient to establish "trapping strips" around the plants to be
protected.

Since the gastropodicides according to the invention are outstandingly well
tolerated by
plants, no limitations apply to the plants to be protected. Thus, all
ornamentals and crop
plants in agriculture, forests and horticulture (also in greenhouses) in all
growth stages can
be protected from slug and snail damage.

The formulation and the use of the slug and snail baits according to the
invention and of the
compositions for controlling wood pests can be seen from the examples which
follow.

The compositions to be used according to the invention part (C) for
controlling gastropods
and wood pests are prepared in the known manner, in the absence of auxiliaries
for
example by grinding and/or straining, for example to obtain a particular
particle size, or by
compressing a solid active ingredient, and in the presence of at least one
auxiliary for
example by intimately mixing and/or grinding the active ingredient with the
auxiliary /
auxiliaries. These processes for the preparation of the compositions according
to the
invention and the use of the macrolides for the preparation of these
compositions are also
the subject of the invention.

As a rule, the compositions in the frame of part (C) of the invention comprise
0.1 to 99%, in
particular 0.1 to 95%, of active ingredient and 1 to 99.9%, in particular 5 to
99.9%, of - at


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least - one solid or liquid auxiliary, it being possible, as a rule, for
surfactants to account for
0 to 25%, in particular 0.1 to 20%, of the compositions (% is in each case per
cent by
weight). While concentrated compositions are more preferred as commercially
available
goods, the consumer uses, as a rule, dilute compositions which have much lower
concen-
trations of active ingredient.

The activity of the compositions according to the invention can be widened
considerably by
adding other, for example insecticidally, acaricidally and/or fungicidally
active ingredients
and adapted to the prevailing circumstances. Examples of suitable added active
ingredients
are the same as mentioned under part (B) of the invention.

In an especially preferred embodiment of the invention, the macrolide compound
is used for
controlling the termites and other wood-destroying pests in the soil, thus
achieving an in-
direct protection of timber constructions. An amount of the macrolide
sufficient to control the
pests is applied to the soil, preferably at an application rate of 1 g to 2000
g per hectare,
especially 2 to 200 g, in particular 5 to 100 g.

Worker termites must work on the pesticide-treated soil to gain access to the
wood. Inevi-
tably, they will take up some of the pesticide and carry it back to the
termite colony and thus
spread the active ingredient in the termite colony.

The active ingredient(s) can also be applied in the form of baits, for example
in the form of
tablets which comprise the active ingredient, such as are described in U.S.
Patent No.
5,096,710. Especially preferably, the macrolide is applied to materials which
are used by
the termites as food and building materials for the termite colony. Examples
of such
materials are board, paper, wood dust, cellulose powder or cotton. Useful
concentrations on
these materials are 0.01 to 10,000 ppm. Such baits are especially efficient
even when
pheromones are additionally employed and wood is used which has already been
attacked
by fungi. Such uses are discussed, for example, in in U.S. Patent No.
5,151,443.

The macrolides according to the invention part (C) are preventatively and/or
curatively
valuable active ingredients with a very favourable biocidal spectrum in the
field of mollusc
and wood-pest control, even at low use concentrations, and are well tolerated
by warm-
blooded species, fish and plants. The active ingredients according to the
invention are
active against all or individual developmental stages of normally sensitive,
but also
resistant, molluscs and wood pests, especially termites. The molluscicidal
action of the
active ingredients according to the invention may manifest itself directly,
i.e. in destruction


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of the pests, either immediately or only after some time has elapsed, or
indirectly, for
example in a reduced oviposition and/or hatching rate, the good action
corresponding to a
destruction rate (mortality) of at least 50 to 60%.

Using the active ingredients according to the invention part (C), it is
possible to control, i.e.
contain or destroy, mollusc damage in particular on plants, mainly on useful
plants and
ornamentals in agriculture, in horticulture and in forests, or pests of the
abovementioned
type which occur on organs of such plants, such as fruits, flowers, foliage,
stalks, tubers or
roots and in some cases even plant organs which grow at a later point in time
are still
protected from these pests.

Suitable target crops for mollusc control are, in particular, cereals, such as
wheat, barley,
rye, oats, rice, maize or sorghum; beet, such as sugar or fodder beet; fruit,
for example
pome fruit, stone fruit and soft fruit, such as apples, pears, plums, peaches,
almonds,
cherries or berries, for example strawberries, raspberries or blackberries;
legumes such as
beans, lentils, peas or soya beans; oil crops such as oil seed rape, mustard,
poppies,
olives, sunflowers, coconuts, castor, cacao or peanuts; the marrow family,
such as
pumpkins, cucumbers or melons; fibre plants such as cotton, flax, hemp or
jute; citrus fruits
such as oranges, lemons, grapefruits or tangerines; vegetables such as
spinach, lettuce,
asparagus, cabbage species, carrots, onions, tomatoes, potatoes, or capsicums;
the laurel
family such as avocado, Cinnamonium or camphor; and tobacco, nuts, coffee, egg
plants,
sugar cane, tea, pepper, grapevines, hops, the banana family, latex plants and
ornamentals.

Other fields of application for the active ingredients according to the
invention part (C) are
the protection of stored products and stores and of materials from molluscs
and wood
pests.

The compositions according to the invention part (C) are also suitable for the
protection of
plant propagation material, for example seed, such as fruits, tubers or
kernels, or plant
propagules, from gastropods and termites, especially gastropods. The
propagation material
can be treated with the composition prior to planting, for example seed prior
to sowing.
Alternatively, the active ingredients according to the invention can be
applied to seed
kernels (coating) either by soaking the kernels in a liquid composition or by
coating them
with a solid composition. Alternatively, the composition can be applied to the
site of planting
when the propagation material is being planted, for example into the seed
furrow during


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sowing. These treatment methods for plant propagation material and the plant
propagation
material treated thus are further subjects of the invention.

The examples which follow are intended to illustrate part (C) of the
invention. They do not
impose any limitation thereto.

Formulation examples

Example F3: Preparation of slug pellets

40 kg of crushed rapeseed (ratio of extracted/non-extracted crushed rapeseed =
65:35),
2.6 kg of a finely ground premix comprising 2.1 kg of macrolide and 500 g of
highly-disperse
silica, 4.7 kg of cold crosslinked cornstarch, 540 g of urea/formaldehyde
resin, 100 g of
isopropanol, 3 kg of sugar beet molasses and 140 g of blue colorant (1,4-
di(isobutylamino)anthraquinone) are introduced in succession into a mixer and
mixed
intimately. This is followed by compression moulding. The product is left to
cool and dry,
and fines are removed using a 0.5 mm screen. This gives a ready-to-use slug
and snail bait
formulation.

Instead of the abovementioned compression moulding method, another, customary
compacting method may also be used for preparing the slug and snail bait
formulation.
Use examples

Examole Al: Test for determining the efficacy of slug and snail pellets
against Deroceras
reticulatum

The efficacy of slug and snail pellets against small slug species, for example
Deroceras
species, is tested in polycarbonate boxes with a 17 cm x 22 cm base. The
bottom of the box
is covered with several layers of cellulose paper which is moistened
sufficiently. The slug
and snail pellets are scattered uniformly over one half of the test area at an
application rate
of 20 particles; the other half remains untreated. To avoid forced behaviour,
the slugs are
additionally given untreated supplementary feed: two potato halves arranged in
diagonally
opposite comers of the box. 10 adult reticulated field slugs (Derocers
reticulatum) are
introduced to the untreated area of each box. Each test is replicated three
times.
Temperature and atmospheric humidity are kept virtually constant during the
entire test
period: 19 and 90 to 95% relative atmospheric humidity. The state of the
slugs is checked
and scored daily on seven consecutive days. When assessing the efficacy, the
mortality


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rate and the number of animals which show symptoms of damage are taken into
consideration.

In this test, the macrolides according to the invention are very effective.

Example A2: Test for determining the efficacy of slug and snail pellets
against Arlon rufus
The efficacy of slug and snail pellets against larger slug species is tested
in plastic test
boxes equipped with a wire mesh. Each box has a base of 0.25 m2. The bottom of
the box
is covered by a 2 to 3 cm deep layer of potting compost. The potting compost
is moistened
sufficiently before the beginning of the experiment. Slug and snail pellets
are scattered
uniformly over the left half of the experimental area at an application rate
of 3.1 g; the right
half remains untreated. To avoid forced behaviour, the slugs are additionally
given
untreated supplementary feed: two potato halves arranged in diagonally
opposite corners of
the box. 10 adult red slugs (Arlon rugus) are introduced to the untreated area
of each box.
Each test is replicated four times. Temperature and atmospheric humidity are
kept virtually
constant during the entire test period: 190 and 90 to 95% relative atmospheric
humidity. The
state of the slugs is checked and scored daily on seven consecutive days. When
assessing
the efficacy, the mortality rate and the number of animals which show symptoms
of damage
are taken into consideration.

In this test, the macrolides according to the invention are very effective.

Example A3: Test for determining systemic efficacy against Deroceras
reticulatum
a) Lettuce plants

A test solution is prepared by dissolving a macrolide sample in 1 ml of
acetone and making
up the solution with water to 50 ml. The roots, previously cleaned with fresh
water, of young
lettuce plants 6 cm in height are immersed for at least two days in this
solution. For each
test, individual leaves are excised from these lettuce plants and placed on a
paper filter in a
9 cm Petri dish. 1 ml of water is pipetted onto each paper filter to keep the
leaves moist
during the experiment. Then, two medium-sized slugs are introduced into each
Petri dish
and the amount of consumed leaves and the mortality is determined over a
period of two
days.

In this test, the macrolides according to the invention show a good action.
b) Seed


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Batches of 10 slugs are introduced into 5 sealed boxes containing compost and
having a
base of 35 cm x 20 cm. In each case 100 treated winter wheat kernels are
scattered
uniformly into four boxes. In the fifth box, 50 treated winter wheat kernels
are distributed
over one side of the box and 50 untreated winter wheat kernels over the other
side of the
box to test the repellent action.

In this test, the macrolides according to the invention are very effective.
Example A4: Action against termites

Wood baits are treated with different amounts of macrolide, and their effect
on hatching
rate and survival of termites is tested. Solutions with concentrations of 0
ppm, 0.1 ppm, 100
ppm and 1000 ppm of the test substance in acetone are used. Water is used in
the control
study. The baits consist of pine wood which have been kept in a natural
environment for
four months.

The termites are collected from infested pieces of wood in the open. To carry
out the wood
bait study, the wood is kept for 48 hours in an oven at 80 C. The dried wood
is then
weighed, and the pieces are placed for 18 hours in solutions of the active
ingredient at the
desired concentration. The pieces of wood are then removed from the solutions,
dried in the
air and reweighed. To determine the action of the baits against termites, the
pieces of wood
thus treated are placed on a thin layer of untreated soil in Petri dishes.

The termites (50 workers and 2 soldiers) are introduced into each Petri dish.
The dishes are
inspected three times per week, over a period of 8 weeks. Insect development,
abnormalities and mortalities are recorded. After 8 weeks, the logs are rinsed
with water
and dried again in an oven for 48 hours at 80 C. Again, the weight of each
piece of wood is
subsequently determined. The weight differential corresponds to the amount of
the wood
consumed by the termites.

In this test, the macrolides according to the invention are very effective.