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Patent Summary

(12) Patent Application:	(11) CA 2395787
(54) English Title:	NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES
(54) French Title:	ACIDES NUCLEIQUES, PROTEINES ET ANTICORPS

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Abstracts

English Abstract

The present invention relates to novel proteins. More specifically, isolated
nucleic acid molecules are provided encoding novel polypeptides. Novel
polypeptides and antibodies that bind to these polypeptides are provided. Also
provided are vectors, host cells, and recombinant and synthetic methods for
producing human polynucleotides and/or polypeptides, and antibodies. The
invention further relates to diagnostic and therapeutic methods useful for
diagnosing, treating, preventing and/or prognosing disorders related to these
novel polypeptides. The invention further relates to screening methods for
identifying agonists and antagonists of polynucleotides and polypeptides of
the invention. The present invention further relates to methods and/or
compositions for inhibiting or enhancing the production and function of the
polypeptides of the present invention.

French Abstract

La présente invention concerne de nouvelles protéines. Plus spécifiquement, l'invention concerne des molécules d'acides nucléiques isolées codant de nouveaux polypeptides. L'invention concerne également des nouveaux polypeptides et des anticorps se fixant à ces polypeptides. De plus, l'invention concerne des vecteurs, des cellules hôtes ainsi que des méthodes de recombinaison et de synthèse permettant la production de polynucléotides et/ou polypeptides ainsi que des anticorps humains. L'invention concerne aussi des méthodes diagnostiques et thérapeutiques utiles pour diagnostiquer, traiter, prévenir et/ou pronostiquer des troubles liés à ces nouveaux polypeptides. L'invention concerne aussi des méthodes de criblage permettant d'identifier des agonistes et des antagonistes de polynucléotides et de polypeptides de l'invention. En outre l'invention concerne des méthodes et/ou des compositions destinées à inhiber ou à augmenter la production et la fonction des polypeptides de la présente invention.

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Patent Details

(51) International Patent Classification (IPC):	C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12N 9/64 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
(72) Inventors (Country):	ROSEN, CRAIG A. (United States of America) RUBEN, STEVEN M. (United States of America) BARASH, STEVEN C. (United States of America)
(73) Owners (Country):	ROSEN, CRAIG A. (Not Available) RUBEN, STEVEN M. (Not Available) BARASH, STEVEN C. (Not Available)
(71) Applicants (Country):	HUMAN GENOME SCIENCES, INC. (United States of America)
(74) Agent:	MBM & CO.
(45) Issued:
(86) PCT Filing Date:	2001-01-17
(87) PCT Publication Date:	2001-08-02
(30) Availability of licence:	N/A
(30) Language of filing:	English

Patent Cooperation Treaty (PCT):	Yes
(86) PCT Filing Number:	PCT/US2001/001302
(87) International Publication Number:	WO2001/055304
(85) National Entry:	2002-06-21

(30) Application Priority Data:

Application No. Country Date 60/179,065 United States of America 2000-01-31 60/214,886 United States of America 2000-06-28 60/246,613 United States of America 2000-11-08 60/246,609 United States of America 2000-11-08 60/246,478 United States of America 2000-11-08 60/246,524 United States of America 2000-11-08 60/246,523 United States of America 2000-11-08 60/249,299 United States of America 2000-11-17 60/249,216 United States of America 2000-11-17 60/249,210 United States of America 2000-11-17 60/249,217 United States of America 2000-11-17 60/249,211 United States of America 2000-11-17 60/215,135 United States of America 2000-06-30 60/249,215 United States of America 2000-11-17 60/249,218 United States of America 2000-11-17 60/249,208 United States of America 2000-11-17 60/249,213 United States of America 2000-11-17 60/249,212 United States of America 2000-11-17 60/249,207 United States of America 2000-11-17 60/249,245 United States of America 2000-11-17 60/249,244 United States of America 2000-11-17 60/249,297 United States of America 2000-11-17 60/249,214 United States of America 2000-11-17 60/216,647 United States of America 2000-07-07 60/249,264 United States of America 2000-11-17 60/249,209 United States of America 2000-11-17 60/249,300 United States of America 2000-11-17 60/249,265 United States of America 2000-11-17 60/250,160 United States of America 2000-12-01 60/250,391 United States of America 2000-12-01 60/256,719 United States of America 2000-12-05 60/251,030 United States of America 2000-12-05 60/251,988 United States of America 2000-12-05 60/251,479 United States of America 2000-12-06 60/216,880 United States of America 2000-07-07 60/251,869 United States of America 2000-12-08 60/251,856 United States of America 2000-12-08 60/251,868 United States of America 2000-12-08 60/251,990 United States of America 2000-12-08 60/251,989 United States of America 2000-12-08 60/254,097 United States of America 2000-12-11 60/259,678 United States of America 2001-01-05 60/246,532 United States of America 2000-11-08 60/246,474 United States of America 2000-11-08 60/246,476 United States of America 2000-11-08 60/217,487 United States of America 2000-07-11 60/246,526 United States of America 2000-11-08 60/249,299 United States of America 2000-11-17 60/249,216 United States of America 2000-11-17 60/249,210 United States of America 2000-11-17 60/249,217 United States of America 2000-11-17 60/249,211 United States of America 2000-11-17 60/249,215 United States of America 2000-11-17 60/249,218 United States of America 2000-11-17 60/249,208 United States of America 2000-11-17 60/249,213 United States of America 2000-11-17 60/217,496 United States of America 2000-07-11 60/249,212 United States of America 2000-11-17 60/249,207 United States of America 2000-11-17 60/249,245 United States of America 2000-11-17 60/249,244 United States of America 2000-11-17 60/249,297 United States of America 2000-11-17 60/249,214 United States of America 2000-11-17 60/249,264 United States of America 2000-11-17 60/249,209 United States of America 2000-11-17 60/249,300 United States of America 2000-11-17 60/249,265 United States of America 2000-11-17 60/218,290 United States of America 2000-07-14 60/250,160 United States of America 2000-12-01 60/250,391 United States of America 2000-12-01 60/256,719 United States of America 2000-12-05 60/251,030 United States of America 2000-12-05 60/251,988 United States of America 2000-12-05 60/251,479 United States of America 2000-12-06 60/251,869 United States of America 2000-12-08 60/251,856 United States of America 2000-12-08 60/251,868 United States of America 2000-12-08 60/251,990 United States of America 2000-12-08 60/220,963 United States of America 2000-07-26 60/251,898 United States of America 2000-12-08 60/254,097 United States of America 2000-12-11 60/259,678 United States of America 2001-01-05 60/220,964 United States of America 2000-07-26 60/225,758 United States of America 2000-08-14 60/180,628 United States of America 2000-02-04 60/225,447 United States of America 2000-08-14 60/225,270 United States of America 2000-08-14 60/225,267 United States of America 2000-08-14 60/225,757 United States of America 2000-08-14 60/224,518 United States of America 2000-08-14 60/224,519 United States of America 2000-08-14 60/225,268 United States of America 2000-08-14 60/225,759 United States of America 2000-08-14 60/225,213 United States of America 2000-08-14 60/225,266 United States of America 2000-08-14 60/184,664 United States of America 2000-02-24 60/225,214 United States of America 2000-08-14 60/226,279 United States of America 2000-08-18 60/226,868 United States of America 2000-08-22 60/226,681 United States of America 2000-08-22 60/227,182 United States of America 2000-08-22 60/227,009 United States of America 2000-08-23 60/228,924 United States of America 2000-08-30 60/229,345 United States of America 2000-09-01 60/229,343 United States of America 2000-09-01 60/229,344 United States of America 2000-09-01 60/186,350 United States of America 2000-03-02 60/229,287 United States of America 2000-09-01 60/229,513 United States of America 2000-09-05 60/229,509 United States of America 2000-09-05 60/230,438 United States of America 2000-09-06 60/230,437 United States of America 2000-09-06 60/231,413 United States of America 2000-09-08 60/232,080 United States of America 2000-09-08 60/231,414 United States of America 2000-09-08 60/231,244 United States of America 2000-09-08 60/232,081 United States of America 2000-09-08 60/189,874 United States of America 2000-03-16 60/231,242 United States of America 2000-09-08 60/231,243 United States of America 2000-09-08 60/231,968 United States of America 2000-09-12 60/232,400 United States of America 2000-09-14 60/232,399 United States of America 2000-09-14 60/232,401 United States of America 2000-09-14 60/233,064 United States of America 2000-09-14 60/233,063 United States of America 2000-09-14 60/232,397 United States of America 2000-09-14 60/233,065 United States of America 2000-09-14 60/190,076 United States of America 2000-03-17 60/232,398 United States of America 2000-09-14 60/234,223 United States of America 2000-09-21 60/234,274 United States of America 2000-09-21 60/234,997 United States of America 2000-09-25 60/234,998 United States of America 2000-09-25 60/235,484 United States of America 2000-09-26 60/235,834 United States of America 2000-09-27 60/235,836 United States of America 2000-09-27 60/236,369 United States of America 2000-09-29 60/236,327 United States of America 2000-09-29 60/198,123 United States of America 2000-04-18 60/236,368 United States of America 2000-09-29 60/236,367 United States of America 2000-09-29 60/236,370 United States of America 2000-09-29 60/237,038 United States of America 2000-10-02 60/237,039 United States of America 2000-10-02 60/237,040 United States of America 2000-10-02 60/236,802 United States of America 2000-10-02 60/237,037 United States of America 2000-10-02 60/239,937 United States of America 2000-10-13 60/239,935 United States of America 2000-10-13 60/205,515 United States of America 2000-05-19 60/241,809 United States of America 2000-10-20 60/241,785 United States of America 2000-10-20 60/240,960 United States of America 2000-10-20 60/241,787 United States of America 2000-10-20 60/241,808 United States of America 2000-10-20 60/241,221 United States of America 2000-10-20 60/241,786 United States of America 2000-10-20 60/241,826 United States of America 2000-10-20 60/244,617 United States of America 2000-11-01 60/246,532 United States of America 2000-11-08 60/209,467 United States of America 2000-06-07 60/246,474 United States of America 2000-11-08 60/246,476 United States of America 2000-11-08 60/246,526 United States of America 2000-11-08 60/246,527 United States of America 2000-11-08 60/246,475 United States of America 2000-11-08 60/246,525 United States of America 2000-11-08 60/246,477 United States of America 2000-11-08 60/246,528 United States of America 2000-11-08 60/246,611 United States of America 2000-11-08 60/246,610 United States of America 2000-11-08

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View Patent Image	Download Patent Image in PDF Format	Size of Image (KB)	Number of Pages
Cover Page	Cover Page	128	2
Abstract	Abstract	97	1
Claims	Claims	165	4
Description	Description	15,349	287
Drawings	Drawings	N/A	N/A
Representative Drawing	Representative Drawing	N/A	N/A

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