Note: Descriptions are shown in the official language in which they were submitted.
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PERFUMED COMPOSITIONS AND METHODS
FOR REDUCING BODY ODORS AND EXCESS MOISTURE
BACKGROUND OF THE INVENTION
Body odor is most commonly caused by fatty acids on skin and by malodors
from microbial sources. The human skin is naturally populated with numerous
micro-
organisms which are nourished by various skin secreted substances (eccrine and
apocrine sweat, and sebum), skin cell debris, breakdown products of the skin
and the
organisms themselves. These unpleasant body odors are mainly organic molecules
which have different structures and functional groups, such as amines, acids,
alcohols, aldehydes, ketones, phenolics, polycyclics, indoles, aromatics,
polyaromatics, etc. They can also be made up of sulfur-containing functional
groups,
such as, thiol, mercaptan, sulfide and/or disulfide groups.
Numerous attempts have been made to control or absorb body odors.
Attempts have been made to deprive the microbials responsible for body odor of
the
moist/humid environment they need to proliferate and grow. Such efforts
include the
use of powders and/or antiperspirants. Body powders and powder-based
compositions of the prior art have limited absorption capabilities.
Antiperspirants are
not always preferred in a body odor control product since, when used over the
entire
body, they may interfere with the body's thermal regulatory process by
inhibiting
perspiration through the action of astringent salts. Additionally, such salts
may be
irritating to a large number of users, particularly when applying them to
sensitive
areas such as the pelvic region.
Other deodorant compositions aimed at combating/controlling odor
associated with skin secretions, which have been described in the chemical and
cosmetic literature, include emulsion sticks or suspensoid sticks, aerosols,
roll-ons,
pads, pump sprays, and even soap bars. These known deodorants attempt to
control
odor through a variety of means. For instance, U.S. Patent No. 5,525,331, to
Betts,
issued 3une 11, 1996, discloses compositions which inhibit the growth of nucro-
organisms in the body-secretions. Deodorants may also include antibacterial
compounds which help destroy/control the amount of bacteria present on skin,
thereby minimizing odor produced via bacterial metabolism of skin secretions.
Zeolites are known odor absorbers. However, these solid odor absorbers, in
addition to known activated charcoal odor absorbers, lose functionality when
wet.
Therefore, when wetted by body fluids or when carried in an aqueous solution,
these
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odor absorbers are not preferred as they lose their desired odor absorbent
characteristics. Furthermore, zeolites can cause "harsh" feel if too much is
deposited
onto the skin.
In addition to the aforementioned attempts at controlling andlor absorbing
body odor, numerous attempts have been made to mask body odors with other
odors
or perfumes. However, perfumes are often inadequate at fully concealing body
odors
and may be irritating to the user when used alone for odor control.
Thus, there remains a need for an improved, perfumed odor and moisture
absorbing composition and methods of use thereof, which is essentially free of
irritating, astringent antiperspirants and which is safe and effective for use
on the
entire body. More particularly, there is a need for a composition which is
left on the
skin and is capable of absorbing a broad spectrum of body odors and excess
moisture
that are not fully suppressed by the aforementioned means.
It has been discovered that such enhanced body odor and optionally moisture
control can be safely provided to the entire body by applying a composition,
which is
left on the skin, which incorporates odor absorbing, uncomplexed
cyclodextrins;
highly effective moisture absorbing ingredients; perfume composition; and a
powder
carrier. Surprisingly, it has been discovered that perfume composition may be
added
without defeating the body odor absorption utility of the uncomplexed
cyclodextrins.
A particular advantage of the present invention is the ability to provide
convenient,
non-irritating odor and optionally moisture protection when applied to
occluded skin
areas such as the pelvic region, the external vagina, the panty-area, the bra-
line, and
skin-folds, which may be very sensitive. Moreover, it has been discovered that
the
aforementioned benefits may be delivered in a powder carrier which also
optionally
delivers skin aid benefits to the user such as protection and/or
moisturization.
All percentages, ratios, and parts herein, in the Specification, Examples, and
Claims are by weight unless otherwise stated. The term "g", as used herein,
means
gram. The term "ml", as used herein, means milliliter. The term "wt", as used
herein,
means weight.
SUNIIyIARY OF THE INVENTION
The present invention relates to a perfumed powder, odor and moisture
absorbing composition comprising from about 0.1 % to about 25%, by weight of
the
composition, of uncomplexed cyclodextrin; optionally, from about 5% to about
60%,
by weight of the composition, of a highly effective moisture absorber; a
perfume
composition selected from the group consisting of from about 0.05% to about
15%,
by weight of the odor absorbing composition, of an encapsulated perfume, and
from
about 0.01% to about 5% by weight of the odor absorbing composition of a free
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perfume, and mixtures thereof; and a powder carrier. The compositions of the
present invention may also contain an additional odor controlling agent
selected from
the group consisting of zeolites, activated charcoal, sodium bicarbonate,
antimicrobial
agents, and antiperspirants. The present invention also relates to methods of
using
the above mentioned compositions.
DETAILED DESCRIPTION OF THE INVENTION
The present invention relates to a perfumed dry powder composition useful in
reducing body odor and moisture from occluded skin sites. The present
invention
also relates to an article of manufacture comprising the compositions herein
deposited on a flexible dispensing means. The composition of the present
invention
comprises dry ingredients preferably having particle sizes of from about 1
micron to
about 100 microns; more preferred from about 1 micron to about 60 microns; and
most preferred from about 1 micron to about 20 microns. As used herein, the
particle size refers to the largest dimension of the particle and to the
ultimate (or
primary) particles.
The term "occluded skin", as used herein, refers to regions of a human or
mammalian body covered by undergarments, such as the pelvic area, panty-area,
and
bra-line; and skin-folds or intertriginous regions, where there is continuing
skin to
skin contact. The term "excess moisture", as used herein, means an undesirable
and/or unhealthy level of body fluids deposited on the skin. The term "body
fluids",
as used herein, includes eccrine sweat, apocrine sweat, sebum, build up of
sensible
moisture from transepidermal water loss, vaginal discharge, urine, and
mixtures
thereof. The term "body odor" as used herein means odors which are generated
as a
result of the natural functioning of a human or mammalian body. Such odors
include,
but are not limited to odors produced by microorganisms of the skin (i.e.
bacterial
decomposition of skin secretions), urine, or vaginal discharge, and mixtures
thereof.
The term "skin" means human or mammalian skin. The term "entire body" means
the
entire external surface of human or mammalian skin. The term "vaginal odor"
relates
specifically to those body odors which emanate from the pelvic region of a
woman,
particularly the vagina and the panty line.
A detailed description of essential and optional components of the present
invention is given below. .
CYCLODEXTRIN: As used herein, the term "cyclodextrin" includes any of
the known cyclodextrins such as unsubstituted cyclodextrins containing from
six to
twelve glucose units, especially alpha-cyclodextrin, beta-cyclodextrin, gamma-
cyclodextrin and/or their derivatives and/or mixtures thereof. The term
"uncomplexed cyclodextrin" as used herein means that the cavities within the
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cyclodextrin in the composition of the present invention should remain
essentially
unfilled prior to application to skin in order to allow the cyclodextrin to
absorb
various odor molecules when the composition is applied to the skin.
Preferred cyclodextrins for use in the present invention are alpha-
cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin and/or their derivatives.
More
preferred are beta cyclodextrin, hydroxypropyl alpha-cyclodextrin,
hydroxypropyl
beta-cyclodextrin, methylated-alpha-cyclodextrin or methylated-beta-
cyclodextrin.
Most preferred is beta-cyclodextryn.
It is also preferable to use a mixture of cyclodextrins. Such mixtures absorb
body odors more broadly by complexing with a wider range of odoriferous
molecules
having a wider range of molecular sizes. The levels of cyclodextrin are from
about
0.1% to about 25%, preferably from about 1% to about 20%, more preferably from
about 2% to about 15%, most preferably from about 3% to about 10%, by weight
of
the composition.
The complexation between cyclodextrin and odorous molecules occurs
rapidly when wetted with body fluids. This is convenient for the user because
the
cyclodextrins, while on dry skin, will not fill their cavities with other
environmental
odors which would otherwise render them less efficient for absorbing body
odors.
More particularly, upon solubiIization of the cyclodextrins by the body
fluids, the
isolated cavities become available to form inclusion complexes with the body
odor
molecules. Thus, ultimately, the availability of solubilized uncomplexed
cyclodextrin
is essential for an effective and efficient odor control performance.
Cyclodextrins having small particle sizes aid in providing higher cyclodextrin
surface availability for odor absorption and therefore are preferred. As used
herein,
the particle size refers to the largest dimension of the particle and to the
ultimate (or
primary) particles. Small particle cyclodextrins of this invention are those
having a
particle size of less than about 12 microns, preferably less than about 10
microns, and
more preferably less than about 5 microns. A more complete description of the
cyclodextrins, cyclodextrin derivatives, and cyclodextrin particle sizes
useful in the
present invention can be found in U.S. Patent No. 5,429,628, Trinh et al.,
issued July
4, 1995, which is incorporated herein by reference in its entirety.
HIGHLY EFFECTIVE MOISTURE ABSORBERS: Highly effective moisture
absorbers are optionally included in the present invention to aid in reducing
excess
moisture on occluded skin and to increase the flowability (the ability to flow
without
caking due to moisture) of the compositions of the present invention. As used
herein,
the phrase "highly effective moisture absorbers" refers to silicas (silicon
dioxide),
silicates or carbonates wherein the silicates and carbonates are formed by
reaction of
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a carbonate or silicate with the alkali (IA) metals, alkaline earth (IIA)
metals, or
transition metals. Preferred highly effective moisture absorbers are calcium
silicate,
amorphous silicas, calcium carbonate, magnesium carbonate, or zinc carbonate,
and
mixtures thereof. Some specific examples of the silicates and carbonates
useful in the
present invention are more fully explained in Van Nostrand Reinhold's
Encyclopedia
of Chemistry, 4th Ed. pages 155, 169, 556, and 849, (1984), which is
incorporated
herein by reference.
Preferred are synthetic versions of the highly effective moisture absorbers,
particularly in regards to silicas and silicates due to safety risks related
to crystalline
silica, Synthetic versions are formed by controlled chemical reactions in a
manufacturing process rather than using a natural, mined version of these
compounds
which is then further refined. Synthetic carbonates useful in the present
invention can
be obtained from various suppliers such as Mallinckrodt or Whittaker, Clark,
and
Daniels. Examples of synthetic calcium silicates useful in the present
invention are
Hubersorb~ 250 or Hubersorb~ 600 available from J.M. Huber.
It is preferred that the highly effective moisture absorbers comprise from
about 5% to about 60%; more preferred, from about 10% to about 50%; and most
preferred, from about 20% to about 40% by weight of the total composition.
PERFUME COMPOSITION: Perfume is an essential component of the present
invention and is included at a level which is non-irntating to the ordinary
user's skin
and/or respiratory tract, yet is discernible by the human sense of smell
either before
and/or after application to the skin. The perfume compositions should be safe
for use
on skin. The perfume compositions useful herein are comprised of perfume
ingredients. The perfume compositions can be either in the form of free
perfume, in
the form of encapsulated perfume, or mixtures thereof. The perfume composition
is
typically present at a level of from about 0.01% to about 20% by weight of the
odor
absorbing composition.
Encapsulated Perfume: It is preferred that an effective amount, typically from
about
0.05% to about IS%, preferably from about 0.1% to about 10%, more preferably
from about 0.2% to about 8%, and even more preferably from about 0.5% to about
5%, by weight of the odor absorbing composition, be in the form of
encapsulated
perfume. Encapsulating perfume helps prevent premature loss of the perfume
composition to the atmosphere as well as helping avoid strong odor which can
be
uncomfortable to the user. As used herein, the phrase "encapsulated perfume"
refers
to perfume compositions which are contained in or, preferably, encapsulated in
a
carrier. Examples of encapsulation means suitable for forming the encapsulated
perfume herein include formation of cyclodextrin/perfume ingredient inclusion
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complexes, coacervate encapsulation, cellular matrix encapsulation, crude
formation
of perfume-filled porous particles, and mixtures thereof. The encapsulated
perfumes
are preferably those which are released by a moisture activation mechanism
whereby
upon being wetted, e.g., by perspiration or other body fluids, the
encapsulated
perfume releases the perfume composition. Thus, skin irritation caused by
perfume is
minimized as encapsulated perfume is released only when wetted.
Cyclodextrin/perfume ingredient inclusion complexes are preferred not only
because they display the preferred moisture activation release, but also for
their
effectiveness and ease of processing. Perfume loading in the cyclodextrin
complex is
fairly low, e.g., from about 10% to about 18% in beta-cyclodextrin/perfume
complex.
The cyclodextrin/perfume ingredient inclusion complexes, particle sizes, and
methods
of formation useful herein, are disclosed in detail in U.S. Patent No.
5,429,628, Trinh
et al., issued July 4, 1995, which is incorporated herein by reference in its
entirety.
At least an effective amount of the cyclodextrin/perfume ingredient inclusion
complex
is to be applied to the odor absorbing compositions herein in order to deliver
the
desired levels of perfume composition. Effective amounts are typically in the
range
of from about 0.01 % to about 10%, preferably from about 0.1 % to about 3%,
more
preferably from about 0.2% to about 2%, by weight of the odor absorbing
composition.
Coacervate perfume encapsulation is a commonly known encapsulation method
wherein a droplet of one or more perfume ingredients is enclosed in a solid
wall
material. In cellular matrix perfume encapsulation, a solid particle contains
many
small droplets of one or more perfume ingredients stably held in the cells.
Water-
soluble (moisture-activated) cellular matrix perfume microcapsules which are
preferred for use herein, and preparation thereof, are described in detail in
U.S.
Patent No. 5,429,628, Trinh et al., issued July 4, 1995, which is incorporated
herein
by reference in its entirety. Water-soluble cellular matrix perfume
microcapsules
useful in the present invention preferably have size of from about 0.5 micron
to about
60 microns, more preferably from about 1 micron to about SO microns, most
preferably from about 2 microns to about 40 microns.
Coacervate perfume encapsulation and cellular matrix perfume encapsulation
are preferred for their perfume loading which can be as high as 60%-80%.
Effective
amounts of coacervate and/or cellular matrix perfume microcapsules are
typically in
the range of from about 0.002% to about 6%, preferably from about 0.007% to
about 1%, more preferably from about 0.01% to about 0.5%, by weight of the
odor
absorbing composition.
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The crudely formed perfume-filled porous particles are used when a slow,
continuous perfume composition release is desired. The perfume-filled porous
particles are perfume ingredients/compositions which are more crudely embedded
in a
matrix and which release via diffusion. Starch matrix perfume-filled porous
particles
can be prepared according to the disclosure in U.S. Pat. 5,267,531, Appel et
al.,
issued Dec. 7, 1993, which is incorporated herein by reference in its
entirety. A
nonlimiting example of useful porous particles, starch granules, are disclosed
by
Whistler et al., Food Technolo~v, July 1994, pp. 104-105, incorporated herein
by
reference. The perfume-filled porous particles can b: coated with suitable
materials
to improve perfume ingredient retention. The preferred particle size for the
porous
particle is from about 10 microns to about 60 microns, more preferably from
about
15 microns to about 40 microns.
Preferably, the encapsulated perfume, whatever form it takes, is composed of
perfume ingredients selected predominantly from two groups of ingredients,
namely,
(a) volatile perfume ingredients having a boiling point at normal pressure of
less than
about 260°C, more preferably less than about 250°C, and (b)
ingredients having
significant low odor detection threshold, and mixtures thereof. The boiling
points of
many perfume ingredients are given in, e.g., "Perfume and Flavor Chemicals
(Aroma
Chemicals)," Steffen Arctander, published by the author, 1969, incorporated
herein
by reference in its entirety. Typically, at least about 50%, preferably at
least about
60%, more preferably at least about 70%, and most preferably at least about
80% by
weight of the encapsulated perfume is composed of perfume ingredients of the
above
groups (a) and (b}.
Nonlimiting examples of the more preferred volatile perfume ingredients are
allo-ocimene, allyl caproate, allyl cyclohexaneacetate, allyl
cyclohexanepropionate,
allyl heptanoate, amyl acetate, amyl propionate, anethol, anisic aldehyde,
anisole,
benzaldehyde, benzyl acetate, benzyl acetone, benzyl alcohol, benzyl butyrate,
benzyl
formate, benzyl iso valerate, benzyl propionate, beta gamma hexenol, butyl
benzoate,
butyl caproate, 4-tert-butylcyclohexyl formate, camphene, camphor gum,
carvacrol,
laevo-carveol, d-carvone, laevo-carvone, cinnamyl formate, cis jasmone, cis-3-
hexenyl acetate, cis-3-hexenyl butyrate, cis-3-hexenyl caproate, cis-3-hexenyl
tiglate,
cis-3-hexenyl vaierate, citral (neral), citronellol, citronellyl acetate,
citronellyl
formate, citronellyl isobutyrate, citronellyl nitrile, citronellyl
oxyacetaldehyde,
citronellyl propionate, cuminic alcohol, cuminic aldehyde, CycIal C,
cyclohexyl ethyl
acetate, beta-damascone, 2-decenal, decyl aldehyde, dihydro myrcenol,
dihydromyrcenyl acetate, dimethyl benzyl carbinol, dimethyl benzyl carbinyl
acetate,
dimethyl benzyl carbinyl propionate, dimethyl phenylethyl carbinyl acetate,
3,7-
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dimethyloctanal, dimethyl octanol, diphenyl oxide, ethyl acetate, ethyl aceto
acetate,
ethyl amyl ketone, ethyl benzoate, ethyl butyrate, ethyl hexyl ketone, ethyl
phenyl
acetate, eucalyptol, fenchyl acetate, fenchyl alcohol, flor acetate (tricyclo
decenyl
acetate), frutene (tricyclo decenyl propionate), gamma methyl ionone, gamma-
nonalactone, geraniol, geranyl acetate, geranyl acetoacetate, geranyl
butyrate, geranyl
formate, geranyl isobutyrate, geranyl nitrite, geranyl propionate, heptyl
acetate, heptyl
isobutyrate, heptyl propionate, hexenol, hexenyl acetate, hexenyl isobutyrate,
hexyl
acetate, hexyl formate, hexyl isobutyrate, hexyl isovalerate, hexyl
neopentanoate,
hexyl tiglate, hydratropic alcohol, hydroxycitronellal, alpha-ionone, beta-
ionone,
gamma-ionone, alpha-irone, isoamyl alcohol, isobornyl acetate, isobornyl
propionate,
isobutyl benzoate, isobutyl caproate, isononyl acetate, isononyl alcohol,
isomenthol,
isomenthone, isononyl acetate, isopulegol, isopulegyl acetate, isoquinoline,
lauric
aldehyde (dodecana(), lavandulyl acetate, ligustral, d-iimonene, linalool,
Iinalool
oxide, linalyl acetate, linalyl butyrate, linalyl isobutyrate, linalyl
formate, linalyl
propionate, menthone, menthyl acetate, methyl acetophenone, methyl amyl
ketone,
methyl anthranilate, methyl benzoate, methyl benzyl acetate, methyl chavicol,
methyl
eugenol, methyl heptenone, methyl heptine carbonate, methyl heptyl ketone,
methyl
hexyl ketone, alpha-iso "gamma" methyl ionone, methyl nonyl acetaldehyde,
methyl
octyl acetaldehyde, methyl octyl ketone, methyl phenyl carbinyl acetate,
methyl
salicylate, myrcene, myrcenyl acetate, neral, nerol, neryl acetate,
nonalactone, nonyl
butyrate, nonyl alcohol, nonyl acetate, nonyl aldehyde, octalactone, octyl
acetate,
octyl alcohol (octanol-2), octyl aldehyde, orange terpenes (d-limonene), para-
cresol,
para-cresyl methyl ether, para-cymene, para-isopropyl para-methyl
acetophenone,
phenethyl anthranilate, phenoxy ethanol, phenyl acetaldehyde, phenyl ethyl
acetate,
phenyl ethyl alcohol, phenyl ethyl dimethyl carbinol, alpha-pinene, beta-
pinene, alpha-
terpinene, prenyl acetate, propyl butyrate, pulegone, rose oxide, safrole,
alpha-
terpinene, gamma-terpinene, 4-terpinenol, terpineol, terpinolene, terpinyl
acetate,
terpinyl propionate, tetrahydro linalool, tetrahydro myrcenol, thymol, delta-
undecalactone, gamma-undecalactone, undecanal, undecenal, undecyl alcohol,
Veratrol, Verdox, Vertenex, and viridine.
Nonlimiting examples of other preferred volatile perfume ingredients which
can be used in perfume compositions of this invention are amyl benzoate, beta-
caryophyllene, cinnamic alcohol, Biphenyl methane, dodecalactone, ethyl methyl
phenyl glycidate, eugenol, fenchyl acetate, gamma-n-methyl ionone,
heliotropine,
indole, isobutyl quinoIine, Lilial (p-t-Bucinal), methyl-N-methyl
anthranilate, para-
methoxy acetophenone, phenethyl butyrate, phenyl heptanol, phenyl hexanol, and
phenoxy ethyl proprionate.
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Preferred encapsulated perfume composition contain at least 5, preferably at
least 6, more preferably at least 7, and even more preferably at least 8
different
volatile perfume ingedients. Most common perfume ingredients which are derived
from natural sources are composed of a multitude of components. When each such
material is used in the formulation of encapsulated perfume compositions of
the
present invention, it is counted as one single ingredient, for the purpose of
defining
the invention.
The use of small amounts of perfume ingredients that have low odor detection
threshold values can improve perfume odor character, even though they are not
as
volatile as perfume ingedients of group (a) which are given hereinabove. The
phrase
"odor detection threshold" of an odorous material means the lowest vapor
concentration of that material which can be olfactorily detected. The odor
detection
threshold and some odor detection threshold values are discussed in, e.g.,
"Standardized Human Olfactory Thresholds", M. Devos et al, IRL Press at Oxford
University Press, 1990; and "Compilation of Odor and Taste Threshold Values
Data", F. A. Fazzalari, editor, ASTM Data Series DS 48A, American Society for
Testing and Materials, 1978, both of said publications being incorporated by
reference. Perfume ingredients that do not belong to group (a) above, but have
a
significantly low odor detection threshold useful herein, are selected from
the group
consisting of ambrox dl, bacdanol, benzyl salicylate, calone, cetalox, cis-3-
hexenyl
salicylate, cymal, ebanol, ethyl anthranilate, ethyl methyl phenyl glycidate,
ethyl
vanillin, dihydro iso jasmonate, gamma dodecalactone, flor acetate,
florhydral,
frutene, heliotropine, alpha ionone, beta ionone, iso eugenol, alpha
isomethylionone,
filial, lyral, methyl dihydrojasmonate, methyl beta naphthyl ketone, beta
naphthol
methyl ether, para hydroxy phenyl butanone, undecalactone gamma, vanillin.,
and
mixtures thereof. These materials are preferably present at low levels in
addition to
the volatile ingedients of group (a), typically less than about 20%,
preferably less
than about 15%, more preferably less than about 10%, by weight of the perfume
composition.
There are also volatile ingredients of group (a) that have a significantly low
odor detection thresholds which are useful herein. Examples of these
ingedients are
allyl amyl glycolate, anethol, benzyl acetone, butyl anthranilate, cinnamic
alcohol,
cyclal C, cyclogalbanate, 4-decenal, ethyl-2-methyl butyrate, eugenol,
damascenone,
alpha damascone, fructone, herbavert, indole, iso cyclo citral, keone,
linalool, methyl
anthranilate, methyl heptine carbonate, methyl isobutenyl tetrahydropyran,
methyl
nonyl ketone, nerol, para anisic aldehyde, phenyl acetaldehyde, and
undecylenic
aldehyde.
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Free Perfume: The perfume composition may also be in the form of a free
perfume.
The term "free perfume", as used herein, means a perfume composition which is
not
encapsulated. Where desired, the free perfume may be diluted in a solvent to
aid in
incorporation into the compositions herein. Suitable solvents include the skin
aids
disclosed herein and solvents found in the Cosmetic Bench Reference 1994
Edition,
page 54, which is incorporated herein by reference. Free perfume may be
composed
of conventional perfume ingredients at a level of from about 0.01 % to about
5%,
preferably from about 0.05% to about 3%, more preferably from about 0.05% to
about 2%, and most preferably from about 0.1 % to about 1 %, by weight of the
odor
absorbing composition.
POWDER CARRIER: The cyclodextrins and highly effective moisture absorbers
useful in the present invention should be dispersed in a pharmaceutically-
acceptable
powder carrier for convenient, uniform application and disbursement onto the
skin.
The term "pharmaceutically-acceptable", as used herein, means a powder
suitable for
topical use on the skin without undue toxicity, irritation, allergic response,
and the
like. The powder carrier also helps prevent any solubilized cyclodextrin from
washing away from the desired skin contact. Powder carriers useful in the
present
invention include powders known in the art to be safe for human skin. Such
powders
include but are not limited to cornstarch (topical starch), talc, rice starch,
oat starch,
tapioca starch, microcrystalline cellulose (for example Avicel~), aluminum
starch
octenyl succinate (sold by National Starch & Chemical Co. as Dry Flo~ Pure,
Dry
Flo~ XT, and/or Dry Flo~ PC), kaolin, and mixtures thereof. Preferred is
cornstarch.
The powder carrier of the present invention will comprise from about 10% to
about 95%, preferably from about 15% to about 80%, more preferably from about
25% to about 50%, by weight of the composition.
ADJUNCT ODOR CONTROLLING AGENTS: Optionally, the compositions of the
present invention may comprise zeolites, carbon odor-controlling agents,
sodium
bicarbonates, antimicrobial agents and/or antiperspirant ingredients for added
body
odor control.
The term "zeolite", as used herein, refers to non-fibrous zeolites. When
included in the present invention, zeolites may be present from about 0.1 % to
about
25%, preferably from about 1% to about 15%, by weight of the composition. A
detailed description of zeolites useful in the present invention is found in
U.S. Patent
No. 5,429,628, Trinh et al., issued July 4, 1995, incorporated herein by
reference in
its entirety.
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Carbon odor-controlling agents described in U.S. Patent No. 5,429,628 may
be used in the present invention at a level of from about 0.1% to about 25%,
by
weight of the composition.
Alkali metal carbonate and/or bicarbonate salts, such as sodium bicarbonate,
potassium bicarbonate, potassium carbonate, cesium carbonate, sodium
carbonate,
and mixtures thereof, may be added to the powder composition of the present
invention in order to help to control acid-type odors. An example of sodium
bicarbonate and its use as an underarm deodorant is found in U.S. Patent No.
4,382,079, to Marschner, issued May 3, 1983, which is incorporated herein in
its
entirety by reference. Preferred salts are sodium carbonate monohydrate,
potassium
carbonate, sodium bicarbonate, potassium bicarbonate, and mixtures thereof.
Alkali
metal carbonate and bicarbonate salts are typically present at a level of from
about
0.1% to about 30%, preferably from about 0.2% to about 20%, more preferably
from
about 0.3% to about 10%, by weight of the powder composition.
The antimicrobial agents of the present invention are selected from a group
consisting of antibacterial agents, antifungal agents, and mixtures thereof.
Antimicrobial agents help destroy and/or control the amount of bacteria and/or
fungi
present on the skin. Preferred antimicrobial agents are zinc phenolsulfonate,
zinc
oxide, triclosan, Zelec~ AM by DuPont, zinc ricinoleate, zinc undecylenate,
and
mixtures thereof. More preferred are zinc phenolsulfonate, zinc oxide, and
triclosan.
Triclosan is available from Ciba-Geigy as Irgasan DP-300. Examples of
antimicrobial
agents useful in the present invention are found in the Cosmetic Bench
Reference,
1994 Edition, page 10, which is incorporated herein by reference. When
included in
the present invention, the antimicrobials are at a level of from about 0.01%
to about
25%. Preferably from about 0.1% to about 10%, by weight of the present
composition.
When used on the underarms, antiperspirant ingredients may be included in
the present invention. Examples of antiperspirants known in the art are found
in the
Cosmetic Bench Reference, 1994 Edition, page 13, which is incorporated herein
by
reference. When included in the present invention, antiperspirants may be
present
from about 0.1% to about 25%, by weight of the composition.
SKIN AmS: The compositions of the present invention also optionally include
skin
aids. The term "skin aids", as used herein, refers to skin protectants,
emollients, and
moisturizers.
Skin protectants useful in the present invention are found in the Cosmetic
Bench Reference, 1994 Edition, page 53; and the Monograph on Skin Protectant
Drug Products for Over-the-Counter Human Use, 21 CFR 347. Preferred skin
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protectants are corn starch, kaolin, mineral oil, sodium bicarbonate,
dimethicone, zinc
oxide, colloidal oatmeal, and mixtures thereof. When present, the skin
protectants
comprise from about 0.1% to about 80%, preferably from about 0.1% to about
30%,
most preferably from about 0.1% to about 10%, by weight of the composition.
Emollients and moisturizers useful in the present invention can be found in
the
Cosmetic Bench Reference, 1994 Edition, pages 27-32 and 46-48, incorporated
herein by reference. Preferred emollients and moisturizers are tocopherol,
tocopheryl
acetate, aloe, vegetable oils, mineral oil, petrolatum, jojoba oil, and
mixtures thereof.
More preferred are encapsulated or spray/freeze dried emollients. The use of
spray/freeze dried or encapsulated emollients keeps the emollients protected
in the
powder carrier until they are released through shearing (such as rubbing
against
undergarments or clothes) or through contact with skin moisture. Examples of
preferred commercial spray/freeze dried aloe useful in the present invention
are
Terra-DryTM Freeze Dried Aloe, Terra-PureTM Freeze or Spray Dried Aloe, and
Terra-Spray TM Spray Dried Aloe, all from Terry Laboratories. When present,
the
emollients/moisturizers comprise from about 0.1% to about 50%, preferably from
about 0.1 % to about 25%, most preferably from about 0.1 % to about 10%, by
weight of the composition.
SLIP COMPOUNDS: The present compositions may optionally comprise slip
compounds. The term "slip compounds", as used herein, refers to compounds
which
have unique structures which provide enhanced slip/lubrication characteristics
of
powders andlor reduced skin to skin friction between intertriginous skin
sites.
SIip compounds of the present invention include polyethylene; nylon;
polytetra-fluoroethylene; silica which is in the form of microspheres,
ellipsoids,
barrel-shapes, and the like; mica, silicone (e.g. dimethicone) and metallic
stearates
(e.g. zinc stearate); and mixtures thereof. Preferred slip compounds are
silicas which
are in the form of microspheres, ellipsoids, barrel-shapes, and the like.
Silica
ellipsoids useful in the present invention are available from DuPont as ZELEC~
Sil.
Silica microspheres are available from KOBO as MSS-500, MSS 500/3, MSS-SOO/H,
MSS-500/3H, MSS-500lN, and MSS-500/3N. Additionally, it is preferred that some
of the silica of the present invention be fumed silica for increased
flowability of the
powder in addition to enhancing the slip characteristics. Fumed silica is
available
from Cabot Corporation (Cab-O-Sil~) and from Degussa (Aerosil~). When present
in the compositions of the invention, the slip compounds comprise from about
0.1%
to about 35% , preferably from about 1% to about 10%, by weight of the
composition.
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BINDERS: The present invention may optionally also include dry or wet binders
to
help promote adhesion of the powder and active ingredients to the skin.
Binders
useful in the present invention are found in the Cosmetic Bench Reference,
1994
Edition, pages 13-14, which is incorporated herein by reference. Preferred
binders
are calcium stearate, zinc stearate, isopropyl myristate, magnesium myristate,
silicone, and mixtures thereof. More preferred are zinc stearate, dimethicone,
and
mixtures thereof. When included in the composition, the binders are at a level
of
from about 0.1% to about 25%, preferably from about 1% to about 15%, by weight
of the composition.
ANTI-PRURITIC AGENTS: Anti-pruritic agents such as those known in the art
may be included in the compositions of the present invention. Examples of anti-
pruritic agents useful in the present invention are Magnesium-L-Lactate,
hydrocortisone, hydrocortisone acetate, and colloidal oatmeal. A description
of anti-
pruritic agents are found in the Handbook of Non Prescription Drugs, 10th
Edition,
p. 529, 1993; which is incorporated herein by reference. When included in the
composition, anti-pruritic agents may be present from about 0.1 % to about
40%, by
weight of the composition.
COLORANTS: Colorants and dyes can be optionally added to the odor absorbing
compositions for visual appeal and performance impression. Colorants suitable
for
use in the present invention are found in the Cosmetic Bench Reference, 1994
Edition, pages 21-22, which is incorporated herein by reference.
PROCESS OF MAKING COMPOSITIONS
The compositions of the present invention are prepared by the following
steps: creating a mixture by mixing cyclodextrin, any highly effective
moisture
absorbers, and optional ingredients in a powder carrier via a commercially
available
mixer such as a vee-blender, double cone blender, or ribbon blender until the
mixture
is uniform; and creating a reduced size mixture using a commercially available
size
reduction technique such as hammer milling, impact milling, ball milling, or
fluid
energy milling until the desired particle size distribution is achieved.
Perfume composition, whether encapsulated or free, may be added to the
present compositions in many different ways. One suitable method of including
encapsulated perfume involves forming cyclodextrin complexes in the manner
described in U.S. Patent 5,429,628, to Trinh et al., issued July 4, 1995,
which is
incorporated herein by reference, and blending the perfume/cylcodextrin
complexes
with the composition above in a final or in an intermediate step. Where
desired, free
perfume may be incorporated by spraying the cyclodextrin, carrier, or any of
the
powder ingredients with the free perfume. Preferably, the free perfume is
blended
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with one or more of the liquid ingredients herein, such as the skin aids,-
prior to the
spraying.
Since the compositions of the present invention are to be applied directly to
the skin or hair, various applicators are useful for delivering the
compositions to the
entire body for maximum odor control. For example, the compositions are
preferably
deposited in a bottle, a canister, a spray dispenser, a manually activated
spray
dispenser, or on a wipe structure which later is contacted with the skin to
transfer the
composition to the skin. Bottles and canisters known in the art are suitable
for use in
delivering the compositions of the present invention. Bottles and canisters
preferably
comprise lids with small apertures for convenient dispensing of the
composition.
The composition of the present invention can also be delivered as a suspended
solution via a spray dispenser or a bottle, such that when applied or sprayed
onto the
skin, the solvent would immediately dry/volatilize off to leave a powder film.
Examples of such suspension forms are aerosols, liquid powder suspensions, or
silicone suspensions. When present in an aerosol composition, the powders of
the
present invention will usually be present in the range of from about 0.1% to
about
I S%, by weight of the composition. The incorporation of a powder into an
aerosol is
more fully explained in U.S. Patent No. 4,078,051, to Pomot et al., issued
March 7,
1978; which is incorporated herein by reference in its entirety. This method
is not
preferred however for use on sensitive areas of the body such as the panty-
area or
other occluded skin areas since skin irritations may result from propellants
commonly
used in aerosol containers.
Preferred is a manually activated spray dispenser which delivers the
composition as a powder without the use of propellants, and without the
composition
being in a solution form. Spray dispensers useful herein are described more
fully in
U.S. Patent No. 2,450,205, to Rose, issued September 28, 1948; and U.S. Patent
No.
2,840,277, to Bach, issued June 24, 1958, both of which are incorporated
herein by
reference in their entireties.
Any wipe structures and/or methods of making the wipe structures commonly
known in the art may be used. The wipe comprises a flexible dispensing means.
The
term "flexible dispensing means", as used herein, includes papers, cloths, non-
wovens, films, foams, sponges, rollers, pads, tissues, cotton balls, and the
like.
Preferred wipe substrates comprise a porous material, such as the non-woven
substrates, foams, or sponges, which are capable of holding the composition
within
the pores of the substrates. Examples of cellulosic non-wovens are described
in U.S.
Patent Number 4,191,609, Trokhan, issued March 4, 1980, which is incorporated
herein by reference in its entirety.
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Techniques for combining the wipe substrates with the composition of the
present invention are well known in the art. Examples of common techniques
include
coating, immersing, dipping, sprinkling, or spraying, the wipe substrate with
the
compositions herein. The composition of the present invention is added to the
wipe
substrate at a level sufficient to provide the desired odor control and/or
other desired
skin benefits.
Packages suitable for use herein are any commonly known in the art and
include resealable packages and those suitable for one time use.
METHODS OF USE
The present invention also encompasses a method of reducing body odor
comprising the application of an effective amount of the compositions
described
herein to skin. The present invention also encompasses a method of reducing
vaginal
odor comprising applying an effective amount of the compositions described
herein
onto a pelvic region, external vagina, and/or panty-area. However, the
compositions
of the present invention should not be inserted into the vagina, nor applied
onto the
vulva. An "effective amount" of the compositions of the present invention, as
used
herein, means an amount sufficient to absorb body odor so that it is less
noticeable by
the human sense of smell. While the determination of an effective amount used
and
the number of uses per day is ultimately left to the discretion of the user,
typically an
effective amount will be from about 1 cc (cubic centimeter) to about 3 cc of
odor
absorbing composition per use, applied about 1 to about 3 times daily, for as
many
days as desired by user.
The compositions herein are topically applied directly to the skin or hair.
The
compositions can be delivered by placing the composition into a dispensing
means
and applying an effective amount via spraying, sprinkling, shaking, or rubbing
the
composition onto the desired skin surface; typically the entire body.
Preferably the
dispensing means is a sprinkling canister, a spray bottle, or a pre-formed
wipe which
comprises a flexible dispensing means.
Alternatively, the user may deposit the composition herein onto a wipe
comprising a flexible dispensing means of his or her own choosing. To do this,
the
user chooses a flexible dispensing means such as a washcloth or puff;
transfers the
composition from a bottle or other suitable container over the chosen flexible
dispensing means, and applies the composition to the desired area of the body.
The
user may also use his/her hand to apply the compositions. The user may use as
much
or as little of the composition as he/she desires, depending upon their
intended use
and degree of odor control necessary.
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The following non-limiting examples illustrate useful perfume compositions
and odor absorbing composition formulations along with methods of use of the
present invention. Perfume compositions A-G are all useful for formulating as
encapsulated perfume. Perfume compositions E-G may also, optionally, be used
as
free perfume.
PERFUME COMPOSITION A PERFUME COMPOSITION B
In redients Wt.% ingredients Wt.%
Ambrox dl 10% in 1.5 Benryl acetate 2.4
DPG
Benzyl acetate 1.9 Cinnamic alcohol 0.1
Benzyl salicylate 3.1 cis 3 Hexenyl acetate 0.3
beta gamma Hexenol 0.4 cis Jasmone 0.4
cis 3 Hexenyl acetate0.5 Citronellol 4.1
cis-3-Hexenyi salicylate2.5 Citronellyl acetate 1.3
Citronella) nitrile1.5 Dimethyl octanol 1.6
Citronellol 9.2 Ethyllinalool 7,3
Cyclal C 0.9 Flor acetate 4.9
Cyclo galbanate 0.5 Frutene 3.3
Dihydro myrcenol 0.9 Geraniol 4.9
Ebanol 0.1 Helional 4.1
Eucalyptol 0.6 Hexyl cinnamic aldehyde16.0
Eugenol 0.5 Hydroxycitronellal 1.6
Flor acetate 8.3 Ionone gamma methyl 5.7
Frutene 4.0 iso E Super 4.1
Geranyl nitrile 0.3 Lyral 3.3
Hexyl cinnamic aldehyde10.5 Methyl dihydro jasmonate16.2
Hydroxycitronellal 2.3 Methyl phenyl carbinyl 0.3
acetate
iso Bornyl acetate 0.2 P. T. Bucinal g_9
iso Cyclo geraniol 0.6 Phenyl ethyl alcohol 4.9
Linalool 1.9 Phenyl hexanol p,g
Linalyl acetate 4.2 Terpineol 3.3
Methyl cedrylone 0.2 Undecylenic aldehyde 0.2
Methyl dihydro jasmonate0.9
Methyl iso butenyl 0.3
tetrahydro pyran
Methyl phenyl carbinyl0.9
acetate
Orange terpenes 17.6
P.T.Bucinal 17.8
Phenyl ethyl alcohol4.6
Prenyl acetate 1.2
_..._..__?.... ._ .. .......... _._._ __......
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PERFUME COMPOSITION C PERFUME COMPOSITION D
In~tredie_nts Wt.% Ingredients Wt.%
4-tertiary Butyl cyclohexyl 10.0 4-tertiary Butyl cyclohexylI2.3
acetate acetate
Bacdanol 0.5 Ambrox DL 10% in DPG 1.6
Cetalox 0.1 Anisic aldehyde 4.5
Citral 1.0 Bacdanol 0.6
CitronelloL 5.0 cis Jasmone 0.1
Damascenone 0.3 Citronellol 6.2
Dihydro myrcenol 1.0 Ethyl cinnamate 1.3
Dimethyl benzyl carbinyl 1.5 Ethyl vanillin 1.7
acetate
Ethyl vanillin 0.5 Eugenol 0.4
Geraniol 2.0 Geraniol 12.3
Geranyl nitrite 0.5 Geranyl acetate 1.2
Heliotropin 5.1 Heliotropin 12.3
Hexyl cinnamic aldehyde 15.4 Hexyl cinnamic aldehyde12.3
Ionone gamma methyl 3.2 Ionone methyl 3.5
iso E Super 3.5 iso Bornyl acetate 1.7
Linalyl acetate 8.1 iso Eugenol 0.3
Methyl anthranilate 1.5 Lauric aldehyde 1.2
Methyl dihydro jasmonate 20.0 Menthyl acetate 0.7
Methyl iso butenyl tetrahydro 0.1 Methyl anthranilate 1.5
pyran
Orange terpenes 10.0 Methyl cinnamate 1.2
para Methoxy acetophenone 0.4 Methyl phenyl carbinyl2.7
acetate
Vanillin 10.3 Phenyl ethyl alcohol 12.3
Undecalactone 0.6
Undecylenic aldehyde 0.6
Vanillin 6.9
PERFUME COMPOSITION E PERFUME COMPOSITION F
Ingredients Wt.% Ingredients Wt.%
Citronellol 10 Benzyl salicylate 20
Benzyl salicylate 15 Benzyl acetate 15
Benzyl acetate 10 Benzophenone 5
Benzophenone 3 Phenyl ethyl alcohol10
Cedrol 2 Linalool 15
Dihydromyrcenol 10 Methyl dihydro 10
jasmonate
Flor acetate 5 Lilial 15
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Phenyl ethyl 15 Phenyl ethyl acetate S -
alcohol
Linalyl acetate 4
Linalool 6
Methyl dihydro 3
jasmonate
Lilial 10
Phenyl ethyl 2
acetate
alpha-Terpineol 5
PERFUME COMPOSITION G
Ingredients Wt.%
CitroneIlol 5
Benzyl salicylate5
Benryl acetate 5
Dihydromyrcenol 5
Flor acetate 5
Phenyl ethyl 20
alcohol
Linalyl acetate 5
Linalool 5
Methyl dihydro 5
jasmonate
Lilial 20
Phenyl ethyl 1
acetate
Vanillin
alpha-Terpineol 8
Anisic aldehyde 2
Cymal 3
EXAMPLE I EXAMPLE II
In redient %W/ Ingredient %W/
W W
Corn Starch (Topical 35.55 Corn Starch (Topical 12.20
Starch) Starch)
Silica (Microspheres)10.00 Talc 10.00
Magnesium Carbonate 8.00 Silica (Microspheres) 10.00
Calcium Silicate, 20.00 Fumed Silica 5.00
Synthetic
Fumed Silica 5.00 Zinc Phenolsulfonate 3.00
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Zinc Phenolsulfonate 3.00 Triclosan 0.30
Triclosan 0.20 Cyclodextrin 6.00
Nylon-12 3.00 Aloe Vera, Freeze/Spray0.50
Dried
Zinc Stearate 3.00 Magnesium Carbonate 8.00
Beta Cyclodextrin 3.00 Nylon-12 5.00
Aloe Vera Freeze/Spray0.10 Calcium Silicate 20.00
Dried
Tocopheryl Acetate 2.00 Zinc Stearate 3.00
Microcapsules
Dipropylene Glyco! 2.00 Tocopheryl Acetate 2.00
Microcapsules
Free Perfume* * 0.15 Mineral Oil 2.00
Dimethicone 5.00 Dimethicone 5.00
Encapsulated Perfume*8.00
Example I may also comprise an Example II may also
anti-pruritic agent such as comprise a zeolite.
Magnesium-L-Lactate.
EXAMPLE III EXAMPLE IV
Ing-redient %W/ Ingredient %W/
W W
Rice Starch 25.00 Aluminum Starch Octenyl12.40
Succinate
Mica 2.00 Silica (Ellipsoids) 8.00
Silica (Ellipsoids) 14.50 Fumed Silica 8.00
Fumed Silica 5.00 Zinc Phenolsulfonate 7.00
Triclosan 0.10 Triclosan 0.60
Aluminum Chlorohydrate5.00 Cyclodextrin 10.00
Cyclodextrin 6.00 Aloe Vera GeUOiI 1.00
Aloe Vera, Freeze/Spray1.00 Magnesium Carbonate 7.00
Dried
Calcium Carbonate 10.00 Calcium Carbonate 3.00
Polyethylene Powder 3.00 Polyethylene Powder 7.00
Calcium Silicate 10.00 Calcium Silicate 15.00
Zinc Stearate 7.00 Zinc Stearate 5.00
Dimethicone 10.00 Mineral Oil 5.00
Encapsulated Perfume* 1.00 Dimethicone 6.00
Free Perfume* * 0.40 Encapsulated Perfume* 4.00
Free Perfume** 1.00
Example III may also comprise
a colorant.
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EXAMPLE V EXAMPLE VI -
Ingredient %W/ Ingredient %W/W
_W
Tapioca Starch 10.00 Corn Starch (Topical 10.00
Starch)
Talc 4.90 Oat Flour/Colloidal Oatmeal8.35
Silica (Microspheres)20.00 Silica (Microspheres) 5.00
Fumed Silica 2.00 Silica (Ellipsoids) 10.00
Zinc Oxide 4.00 Fumed Silica 5.00
Triclosan 1.00 Zinc Oxide 2.00
Cyclodextrin 4.00 Triclosan 0.40
Aloe Vera GeUOiI 2.00 Cyclodextrin 5.00
Magnesium Carbonate5.00 Aloe Vera GeU0i1 2.00
Calcium Carbonate 4.00 Magnesium Carbonate 4.00
Nylon-12 10.00 Calcium Carbonate 5.00
Calcium Silicate 15.00 Nylon-12 4.00
Zinc Stearate 6.00 Polyethylene Powder 4.00
Isopropyl Myristate4.00 Calcium Silicate 10.00
Dimethicone 5.00 Zinc Stearate 10.00
Encapsulated Perfume*3.00 Tocopheryl Acetate 5.00
Mircocapsules
Free Perfume** 0.10 Dimethicone 10.00
Free Perfume** 0.25
Example VI may also
comprise sodium bicarbonate.
EXAMPLE VII EXAMPLE VIII
Ingredient %W/ In redient %WlW
_W
Corn Starch 6.80 Corn Starch (Topical 43.10
Starch)
Kaolin 4.00 Silica (Microspheres) 30.00
Silica (Microspheres)5.00 Zinc Phenolsulfonate 3.00
Silica (Ellipsoids)5.00 Triclosan 0.30
Fumed Silica 5.00 Nylon-12 10.00
Zinc Phenolsulfonate2.00 Beta Cyclodextrin 3.00
Triclosan 0.20 Tocopheryl Acetate 5.00
Microcapsules
Cyclodextrin 8.00 Dipropylene Glycol 0.30
Aloe Vera GeU0i1 3.00 Free Perfume** 0.30
Magnesium Carbonate10.00 Dimethicone 5.00
Nylon-12 2.00
Polyethylene Powder5.00
Calcium Silicate 25.00
Zinc Stearate 7.00
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Tocopheryl Acetate 3.00
Microcapsules
Isopropyl Myristate 2.00
Dimethicone 5.00
Encapsulated Perfume* 2.00
EXAMPLE IX
Ingredient %W/W
Corn Starch (Topical 47.50
Starch)
Silica (Microspheres) 40.00
Triclosan 0.30
Zinc Stearate 3.00
Beta Cyclodextrin 3.00
Dipropylene Glycol 0.60
Free Perfume** 0.60
Dimethicone 5.00
EXAMPLE X EXAMPLE XI
In red dient %W/W Ingredient %W/
W
Corn Starch (Topical 60.80 Corn Starch (Topical 50.00
Starch) Starch)
Silica (Microspheres) 2.00 Talc 10.00
Fumed Silica 2.00 Silica (Microspheres) 3.00
Zinc Phenolsulfonate 3.00 Fumed Silica 1.00
Triclosan .20 Zinc Phenolsulfonate 3.00
Cyclodextrin 3.00 Triclosan 0.30
Aloe Vera, Freeze/Spray1.00 Cyclodextrin 13.00
Dried
Nylon-12 5.00 Aloe Vera, Freeze/Spray 0.50
Dried
Zinc Stearate 7.00 Nylon-12 5.00
Tocopheryl Acetate 2.00 Zinc Stearate 3.00
Microcapsules
Dimethicone 10.00 Tocopheryl Acetate 2.00
Microcapsules
Encapsulated Perfume* 4.00 Mineral Oil 2.00
Dimethicone 5.00
Free Perfume* * 0.20
Encapsulated PerFume* 2.00
Example X may also comprise Example VI may also
a colorant. comprise a zeolite.
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EXAMPLE XII EXAMPLE XIII
Ingredient %W/W Ingredient %W/
W
Rice Starch 51.00 Aluminum Starch Octenyl30.20
Succinate (Dry Flo~Pure)
Mica 2.00 Silica (Ellipsoids) 4.00
Silica (Ellipsoids) 2.00 Zinc Phenolsulfonate 7.00
Fumed Silica 1.00 Triclosan 0.60
Triclosan 0.50 Cyclodextrin 10.00
Aluminum Chlorohydrate5.00 Aloe Vera GeU0i1 1.00
Cyclodextrin 6.00 Zeolite 10.00
Aloe Vera, Freeze/Spray1.00 Talc 13.60
Dried
Polyethylene Powder 5.00 Polyethylene Powder 7.00
Zinc Stearate 5.00 Zinc Stearate 5.00
Tocopheryl Acetate 3.00 Mineral Oil 5.00
Oil (Vit.
E. Acetate)
Dimethicone 10.00 Dimethicone 6.00
Nylon N-12 5.00 Free Perfume** 0.60
Free Perfume* * 0.50
Encapsulated Perfume*3.00
Example VII may also
comprise a zeolite.
EXAMPLE XIV EXAMPLE XV
Ingredient %W/W In redient %W1W
Tapioca Starch 46.50 Corn Starch (Topical 29.00
Starch)
Talc 4.90 Oat Flour/Colloidal 16.35
Oatmeal
Silica (Microspheres)2.50 Silica (Microspheres) 2.50
Fumed Silica 2.00 Silica (Ellipsoids) I.50
Zinc Oxide 4.00 Kaolin 8.00
Triclosan 1.00 Zinc Oxide 2.00
Cyclodextrin 4.00 Triclosan 0.40
Aloe Vera GeUOiI 2.00 Cyclodextrin 5.00
Nylon-12 10.00 Aloe Vera GeU0i1 2.00
Zinc Stearate 6.00 Nylon-12 4.00
Isopropyl Myristate4.00 Polyethylene Powder 4.00
Dimethicone 5.00 Zinc Stearate 10.00
Free Perfume** 0.10 Tocopheryl Acetate 5.00
Mircocapsules
Encapsulated Perfume*8.00 Dimethicone 10.00
Free Perfume** 0.25
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EXAMPLE XVI
Inr~redient %W/W
Corn Starch (Topical Starch) 49.00
Kaolin 14.50
Silica (Microspheres) 2.50
Silica (Ellipsoids) I.50
Fumed Silica 0.50
Zinc Phenolsulfonate 2.00
Triclosan 0.20
Cyciodextrin 8.00
Aloe Vera Gel/Oil 3.00
Nylon-12 2.00
Polyethylene Powder 5.00
Tocopheryl Acetate 3.00
Microcapsules
Isopropyl Myristate 2.00
Dimethicone 5.00
Free Perfume* * 0.80
Encapsulated Perfume* 1.00
*Any encapsulated perfume in Examples I-XVI may comprise any of the above
Perfume Compositions of Examples A-G.
**Any free perfume in Examples I-XVI may comprise any of the above Perfume
Compositions of Examples E-G.
Prepare the above Examples by the following steps: create a first mixture by
mixing cyclodextrin, dry ingredients, and a powder earner in a commercially
available
mixer such as a vee-blender, double cone blender, or ribbon blender until the
mixture
is uniform; reduce the particle size of the mixture using a
grinding/pulverizing
technique such as hammer milling, impact milling, ball milling, or fluid
energy milling;
and create a second mixture by adding any liquid phase emollients,
moisturizers,
and/or skin protectants to the mixture, preferably using spray atomization
while
mixing for a more even dispersion. The second mixture can then undergo a
second
pulverizing/grinding step, and if desired, an air classifying operation. Where
the
above Examples include free perfume compositions, creating the second mixture
may
include the addition of the perfume compositions into the liquid phase. Where
the
above Examples include encapsulated perfume, the encapsulated perfume may be
added with the dry ingredients when creating the first mixture; or,
preferably, may be
added in a final step of creating a third mixture by adding the encapsulated
perfume
to the second mixture with mixing.
1
CA 02293663 1999-12-08
- WO 98/56340 PCT1US98/11811
24
Preparation for Application to Skin: The compositions of the present
invention, such
as those formed from the examples may be loaded onto a wipe or deposited into
a
spray device or canister. The compositions may be applied directly onto the
skin or
onto a flexible dispensing means of the user's choosing for convenient
application to
the skin. To prepare wipes, coat, sprinkle, or spray the composition onto a
dry
flexible dispensing means until desired coating or thickness of composition on
the
flexible dispensing means is achieved. To prepare spray, deposit the
composition into
the selected spray package. Close the package for storage until consumer use.
To
prepare a pressurized aerosol spray, transfer the composition into a suitable
container. Pressurize and seal the container after injection of propellant
materials.
Example XVII A woman with stress urinary incontinence finds that the wetness
associated with this condition causes vaginal odor which she wants to remove
from
the skin and control. After urinating, the woman wipes her external vagina and
pelvic
region with a wipe containing the composition in Example X. This woman notices
less vaginal odor after using the wipe.
Example XVIII A large-breasted, obese woman finds that when she exercises, she
tends to experience sweating and skin chafing under the breasts. Before and
after
exercising, she applies the composition from Example III or IX via a manual
spray
bottle. She sprays the perfumed composition under her breasts. The woman also
applies the composition into intertriginous regions between her abdominal skin
folds
as well as other occluded skin sites. She notices less body odor and excess
moisture
after using the powder spray.
Example XIX A man has severe allergies to cosmetic deodorants,
antiperspirants,
and heavy colognes and avoids using such products. This results in
uncontrolled and
embarrassing body odor. His doctor suggests applying the mild, lightly
perfumed
odor absorbing composition of Example I or XV after showering. The man applies
the composition to his entire body via a spray each morning after showering,
and
suffers no allergic reaction. The man feels comfortable without the
embarrassment of
lingering, uncontrollable body odor. The man keeps a pouch of wipes which also
contain the composition of Example I or XV, for convenient and discreet
reapplication as needed.
T.
