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(12) Patent: | (11) CA 2352528 |
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(54) English Title: | PHOSPHATIDYL-L-SERINE AND PHOSPHATIDIC ACID COMPOSITION AS ANTI-DEPRESSANT, STRESS SUPPRESSOR AND MOOD IMPROVER |
(54) French Title: | COMPOSITION ACIDE PHOSPHATIDIQUE ET DE PHOSPHATYIDYL-L-SERINE COMME ANTIDEPRESSEUR, REDUCTEUR DE STRESS ET PSYCHOTROPE |
Status: | Expired and beyond the Period of Reversal |
(51) International Patent Classification (IPC): |
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(72) Inventors : |
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(73) Owners : |
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(71) Applicants : |
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(74) Agent: | SMART & BIGGAR LP |
(74) Associate agent: | |
(45) Issued: | 2005-12-06 |
(22) Filed Date: | 2001-07-06 |
(41) Open to Public Inspection: | 2002-04-23 |
Examination requested: | 2002-09-04 |
Availability of licence: | N/A |
Dedicated to the Public: | N/A |
(25) Language of filing: | English |
Patent Cooperation Treaty (PCT): | No |
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(30) Application Priority Data: | ||||||
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An anti-depressant, mental & emotional stress suppressor and mood improver having a prominent action for decreasing blood cortisol level and serotonin reuptake and has an effect of alleviating symptoms associated with depression and mental & emotional stress of a subject administered with the improver. The improver contains as the effective ingredient a combination of phosphatidyl-L-serine and phosphatidic acid, or the salts thereof, comprising at least 200 (w/w) phosphatidyl-L-serine and typically within the range of about 20%-40% of phosphatidyl-L-serine, out of the total phospholipid content of the composition and at least 3% (w/w) of phosphatidic acid, preferably above about 10% and typically within the range of about 20%-40% of phosphatidic acid, out of the total phospholipid content of the composition. The phosphatidyl-L-serine and phosphatidic acid has a structural fatty acid chain derived from at least one raw material lecithin selected from the group consisting of soy bean lecithin, rapeseed lecithin or egg yolk lecithin. Using the raw material lecithin as the substrate, phosphatidyl-L-serine and phosphatidic acid can be produced by enzymatic conversion utilizing phospholipase-D.
Un agent antidépresseur, suppresseur de stress émotionnel et mental, et améliorateur de l'humeur, dont l'action prédominante est d'abaisser le niveau de cortisol sanguin et la réabsorption de la sérotonine, et qui soulage les symptômes associés avec la dépression et le stress mental et émotionnel chez un sujet ayant reçu cet agent d'amélioration. L'agent d'amélioration contient comme ingrédient actif un mélange de phosphatidyl-L-sérine et d'acide phosphatidique, ou de leurs sels, comprenant au moins 20 % (en poids) de phosphatidyl-L-sérine et typiquement, environ entre 20 %-40 % de phosphatidyl-L-sérine, sur la concentration totale en phospholipides du mélange et au moins 3 % (en poids) d'acide phosphatidique, de préférence plus de 10 % environ, et typiquement entre environ 20 %-40 % d'acide phosphatidique, sur la concentration totale en phospholipides du mélange. La phosphatidyl-L-sérine et l'acide phosphatidique présentent une chaîne d'acide gras structurale dérivée d'au moins une lécithine en tant que matière première provenant du groupe comprenant la lécithine de soja, la lécithine de colza ou la lécithine de jaune d'oeuf. En utilisant cette matière première de lécithine comme substrat, la phosphatidyl-L-sérine et l'acide phosphatidique peuvent être produits par conversion enzymatique utilisant une phospholipase D.
Note: Claims are shown in the official language in which they were submitted.
Note: Descriptions are shown in the official language in which they were submitted.
Sorry, the representative drawing for patent document number 2352528 was not found.
2024-08-01:As part of the Next Generation Patents (NGP) transition, the Canadian Patents Database (CPD) now contains a more detailed Event History, which replicates the Event Log of our new back-office solution.
Please note that "Inactive:" events refers to events no longer in use in our new back-office solution.
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Description | Date |
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Time Limit for Reversal Expired | 2020-08-31 |
Inactive: COVID 19 - Deadline extended | 2020-08-19 |
Inactive: COVID 19 - Deadline extended | 2020-08-19 |
Inactive: COVID 19 - Deadline extended | 2020-08-06 |
Inactive: COVID 19 - Deadline extended | 2020-08-06 |
Inactive: COVID 19 - Deadline extended | 2020-07-16 |
Inactive: COVID 19 - Deadline extended | 2020-07-16 |
Inactive: COVID 19 - Deadline extended | 2020-07-02 |
Inactive: COVID 19 - Deadline extended | 2020-07-02 |
Common Representative Appointed | 2019-10-30 |
Common Representative Appointed | 2019-10-30 |
Letter Sent | 2019-07-08 |
Maintenance Request Received | 2018-06-07 |
Change of Address or Method of Correspondence Request Received | 2018-03-28 |
Inactive: Late MF processed | 2017-10-16 |
Maintenance Request Received | 2017-10-16 |
Letter Sent | 2017-07-06 |
Maintenance Request Received | 2016-06-06 |
Maintenance Request Received | 2015-06-02 |
Maintenance Request Received | 2014-06-19 |
Maintenance Request Received | 2013-06-25 |
Inactive: IPC from MCD | 2006-03-12 |
Inactive: IPC from MCD | 2006-03-12 |
Grant by Issuance | 2005-12-06 |
Inactive: Cover page published | 2005-12-05 |
Pre-grant | 2005-09-27 |
Inactive: Final fee received | 2005-09-27 |
Letter Sent | 2005-04-22 |
Notice of Allowance is Issued | 2005-04-22 |
Notice of Allowance is Issued | 2005-04-22 |
4 | 2005-04-22 |
Inactive: IPC assigned | 2005-04-20 |
Inactive: Approved for allowance (AFA) | 2005-04-12 |
Amendment Received - Voluntary Amendment | 2005-03-02 |
Inactive: S.30(2) Rules - Examiner requisition | 2004-11-08 |
Inactive: S.29 Rules - Examiner requisition | 2004-11-08 |
Amendment Received - Voluntary Amendment | 2004-01-16 |
Amendment Received - Voluntary Amendment | 2003-12-16 |
Inactive: Entity size changed | 2003-07-10 |
Amendment Received - Voluntary Amendment | 2002-11-14 |
Letter Sent | 2002-10-01 |
All Requirements for Examination Determined Compliant | 2002-09-04 |
Request for Examination Requirements Determined Compliant | 2002-09-04 |
Request for Examination Received | 2002-09-04 |
Application Published (Open to Public Inspection) | 2002-04-23 |
Inactive: Cover page published | 2002-04-22 |
Inactive: Applicant deleted | 2002-04-19 |
Inactive: Applicant deleted | 2002-04-19 |
Letter Sent | 2001-12-04 |
Inactive: Single transfer | 2001-11-07 |
Inactive: First IPC assigned | 2001-09-07 |
Inactive: IPC assigned | 2001-09-07 |
Inactive: Courtesy letter - Evidence | 2001-08-07 |
Inactive: Filing certificate - No RFE (English) | 2001-07-31 |
Application Received - Regular National | 2001-07-31 |
There is no abandonment history.
The last payment was received on 2005-06-21
Note : If the full payment has not been received on or before the date indicated, a further fee may be required which may be one of the following
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Note: Records showing the ownership history in alphabetical order.
Current Owners on Record |
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LIPOGEN LTD. |
Past Owners on Record |
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DAVID RUTENBERG |