Note: Descriptions are shown in the official language in which they were submitted.
File No. P4334CA00
Title: NON-CARCINOGENIC CREAM FOR DELIVERY OF ACTIVE
INGREDIENT INTO THE DERMIS
BACKGROUND
(a) Field
[0001] The subject matter disclosed generally relates to a non-
carcinogenic cream for delivery of active ingredients into the dermis of a
patient for pain related to joint, lymphatic and blood circulation, nerve and
skin.
(b) Related Prior Art
[0002] Many pharmaceutical analgesic topical compositions for
treating
muscular cramps, soreness and pain contain irritants, counter-irritants and
toxic ingredients that are mostly carcinogenic and mask pain instead of
alleviating it. These compositions irritate the skin and do not treat all the
symptoms, causes pain and side effects and/or increase the risk of
developing cancer.
[0003] Homeopathy is an ancient healing art and forms a vital part
of
medical therapy. The practice of homeopathy is widespread, particularly in
eastern cultures and many European countries. Homeopathic medicine
teaches the use of natural based remedies and, as such, provides an
alternative to traditional allopathic medicine which relies heavily on the use
of
petrochemical based pharmaceuticals. There has been a large increase in
interest in homeopathic medicine in the United States in recent years due, in
large part, to a growing disenchantment with allopathic medications and the
complications and side effects arising from their use. Frequently, the
administration of allopathic medications results in serious side effects more
deleterious to the patient than the basic condition being treated. Today, more
and more individuals are looking for a gentler, safer path to good health free
of the risks and side effects associated with traditional allopathic
medicines.
[0004] In order to relieve pain in many inflammatory injuries or
diseases
it is desirable to promote healing, improve circulation to tissues nerves,
provide anti-inflammatory activity, while alleviating pain instead of masking
it.
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Many injuries have a multiplicity of symptoms which require a cocktail of
ingredients working together in order to provide relief.
[0005] Furthermore, it is desirable to obtain deep penetration of the
active ingredients so as to act in the dermis to provide the proper response
to
cause healing of the injury and/or inflammation.
[0006] It is further desirable to provide an analgesic which does not
rely
upon counter-irritants that act by causing a superficial inflammation on the
skin, which numbs the sensation of pain perceived by the sensory organ and
results in only masking the pain instead of alleviating it.
[0007] It is further desirable to relax soft tissues, vasodilate
blood
vessels which are vasoconstricted so as to allow blood to flow normally,
returning nutrients and oxygen to areas to promote healing. It is also
desirable
to release nerves which have been entrapped by hypercontraction of muscle
tissue.
[0008] U.S. Pat. No. 5,162,037 to Whitson-Fischman discloses a
method for treating pathogenic conditions of the body by preparing a
homeopathic mixture of at least one herb or herbal extract which exhibits
therapeutic property and add a magnetically permeable substance to the
mixture, magnetizing the resulting mixture in a magnetic field during delivery
to impart a substantially unipolar magnetic charge on said mixture; and
administering the magnetized mixture through one or more specific
acupuncture points of the body which are associated with producing a desired
response to the particular condition being treated.
[0009] U.S. Pat. No. 5,795,573 to Paradise discloses homeopathic
topical anti-inflammatory and pain relieving compositions. Although the
compositions active ingredients include homeopathic extracts from Arnica
Montana, Rhus toxicodendron and Aesculus hippocastanum and belladonna,
they also include carcinogenic ingredients such as PEG, PPG,
ethoxydiglycol, paraben, isopropyl myristate and Dowicil 200TM
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File No. P4334CA00
[0010] Finally, it is highly desirable to have a non-carcinogenic
cream
for the treatment of pain.
SUMMARY
[0011] It is an object of the present disclosure to provide a non-
carcinogenic cream for delivery of active ingredients in the dermis of a
patient
for pain related to joint, lymphatic and blood circulation, nerve and skin.
[0012] According to an embodiment, there is provided a non-
carcinogenic cream for delivery of active ingredients in the dermis of a
patient,
comprises a synergistic combination of
= about 10 to 25% of oil
= about 10 to 25 of emulsifier
= about 1 to 12% of preservative
= about 45 to 80% of water, aloe water or hamamelis water, and
= about 1 to 25% of at least one homeopathic active ingredient chosen
from pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale,
symphytum officinalis, salix alba, harpagophytum, bryonia, capsicum,
rhododendron, benzoic acid, salicilicum acid, arnica montana, atropa
belladonna, achillea millefolium, hamamelis, agaricus, aesculus, mercurius
solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia,
echinacea purpurea, scrofularia nosada, pulsatilla, aconitum napellus,
hypericum perforatum, bellis perennis, matricaria chamomilla, ranunculus,
phytolacca decandra, dulcamara solanum, kalmia, actea racemosa, spigelia,
gnaphalium, calendula officinalis, hepar sulphuris, somniferrum, calcarea
fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica
urens, aloe, graphite, petroleum or a synergistic combination thereof.
[0013] The oil is chosen from emu oil, olive oil, argan nut oil,
sunflower/safflower oil, coconut oil, castor oil, avocado oil, jojoba oil,
lavender
oil, grape seed oil, poppy seed oil, sunflower oil or wheat germ oil.
[0014] The emulsifier is chosen from oleyl oleate, cetearyl
alcohol,
cetearyl wheat straw glucosides, glyceryl stearate, sodium stearoyl lactylate,
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cetearyl olivate, sorbitan olivate, propylene glycol esters (pgms), borax with
bees wax, bees wax, BTMS 25%, carbomer, emulsifying wax¨NF, lecithin,
stearate, silky emulsifying wax, stearyl alcohol NF, shea butter, cocoa
butter,
coconut oil or stearic acid.
[0015] The preservative is chosen from a combination of glucose,
glucose oxidase and lactoperoxidase (BiovertTM enzymes), a combination of
benzyl alcohol, salicylic acid, glycerin and sorbic acid (GeoguardTM ECT),
polylysine, natamycin, nisin, isothiazolinones, benzoic acid ¨ sodium
benzoate, sorbic acid - potassium sorbate, levulinic acid, anisic acid,
rosemary oil extract, grapefruit seed extract, T-50 vitamin E oil, jermaben
11,
or jermaben 11-E.
[0016] The non-carcinogenic cream for improving joint conditions
contains at least one homeopathic active ingredient chosen from
pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale,
symphytum officinalis, salix alba, harpagophytum, bryonia, capsicum,
rhododendron, benzoic acid, salicilicum acid or a synergistic combination
thereof.
[0017] The non-carcinogenic cream for improving blood circulation
contains at least one homeopathic active ingredient chosen from arnica
montana, atropa belladonna, achillea millefolium, hamamelis, agaricus,
aesculus or a synergistic combination thereof.
[0018] The non-carcinogenic cream for improving lymphatic
circulation
contains at least one homeopathic active ingredient chosen from mercurius
solubilis, mercurius iodatus, conium maculatum, echinacea angustifolia,
echinacea purpurea, gallium aparine, phytolacca decandra, scrofularia
nosada, pulsatilla or a synergistic combination thereof.
[0019] The non-carcinogenic cream for improving sensitive nerves
contains at least one homeopathic active ingredient chosen from aconitum
napellus, hypericum perforatum, bellis perennis, matricaria chamomilla,
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ranunculus, phytolacca decandra, dulcamara solanum, kalmia, actea
racemosa, spigelia, gnaphalium or a synergistic combination thereof.
[0020] The non-carcinogenic cream for reducing scars and/or
keloids of
the skin contains at least one homeopathic active ingredient chosen from
pancreatinum, calendula officinalis, hepar sulphuris, somniferrum, calcarea
fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine, urtica
urens, aloe, graphite, petroleum or a synergistic combination thereof.
[0021] The preferred non-carcinogenic cream comprises
= about 14.7% of oil;
= about 12.8% of emulsifier;
= about 1.05% of preservative; and
= about 65.67% of water; and
= about 4.78% the homeopathic active ingredient comprises at least
pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale,
symphytum officinalis, arnica montana, atropa belladonna, achillea
millefolium, hamamelis, mercurius solubilis, mercurius iodatus, conium
maculatum, echinacea angustifolia, echinacea purpurea, aconitum napellus,
hypericum perforatum, bellis perennis, matricaria chamomilla, calendula
officinalis and hepar sulphur's.
[0022] According to another embodiment, there is provided a non-
carcinogenic cream for delivery of active ingredients in the dermis of a
patient
comprises a synergistic combination of
= about 10 to 25% of oil
= about 10 to 25 of emulsifier
= about 1 to 12% of preservative
= about 45 to 80% of water, aloe water or hamamelis water, and
= about 1 to 25% of a synergistic combination of at least five
homeopathic active ingredients comprising
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O from at least one of aconitum napellus, hypericum perforatum,
bellis a first ingredient chosen from at least one of ruts graveolens,
ledum palustre, colchicum autumnale or symphytum officinalis;
O a second ingredient chosen from at least one of arnica montana,
atropa belladonna, achillea millefolium or hamamelis;
O a third ingredient chosen from at least one of mercurius solubilis,
mercurius iodatus, conium maculatum, echinacea angustifolia or
echinacea purpurea;
O a fourth ingredient chosen from at least one perennis, matricaria
chamomilla, gallium aparine, phytolacca decandra, scrofularia
nosada, or pulsatilla;
O a fifth ingredient chosen from at least one of pancreatinum,
calendula officinalis, hepar sulphuris, somniferrum, calcarea
fluorica, thiosinaminum, hydrastis, arctium lappa, gallium aparine,
urtica urens, aloe, graphite, or petroleum.
[0023] Features and advantages of the subject matter hereof will
become more apparent in light of the following detailed description of
selected
embodiments, as illustrated in the accompanying figures. As will be realized,
the subject matter disclosed and claimed is capable of modifications in
various respects, all without departing from the scope of the claims.
Accordingly, the drawings and the description are to be regarded as
illustrative in nature, and not as restrictive and the full scope of the
subject
matter is set forth in the claims.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0024] According to the invention, there is provided a non-
carcinogenic
cream for topical application for delivery of active ingredients in the dermis
of
a patient for pain related to joint, lymphatic and blood circulation, nerve
and
skin.
[0025] The composition can be used in combination with an
occlusive
bandage.
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[0026] It has been found that the non-carcinogenic cream for
delivery of
active ingredients in the dermis of a patient for treating pain, includes a
synergistic combination of
= about 10 to 25% of oil
= about 10 to 25% of emulsifier
= about 1 to 12% of preservative
= about 45 to 80% of water, aloe water or hamamelis water; and
= about 1 to 25% of at least one homeopathic active ingredient chosen
from pancreatinum, ruta graveolens, ledum palustre, colchicum autumnale,
symphytum officinalis, arnica montana, atropa belladonna, achillea
millefolium, hamamelis, mercurius solubilis, mercurius iodatus, conium
maculatum, echinacea angustifolia, echinacea purpurea, aconitum napellus,
hypericum perforatum, bellis perennis, matricaria chamomilla, calendula
officinalis, hepar sulphuris or a synergistic combination thereof.
[0027] Although greater amounts of the homeopathic active
ingredient
can be used in the composition it has been found that about 2 to 25% by
weight of the combination of extracts is effective.
[0028] The compositions of the invention can be used in
combination
with other herbs or herbal extracts. For example, it may be desirable to thin
the blood or to better promote circulation such as Naja and Gratalus
horridum.
[0029] To condition the skin graphite and/or trace minerals such
as
copper and zinc salts may be included.
[0030] Other anti-inflammatory agents such as Lachesis Ninta that
contains enzymes which relieves muscle tightness and cramps can be
included in the composition.
[0031] The combinations as used herein stimulate the body's self
healing mechanism by promoting circulation in the micro-capillary system.
This restores blood flow to the inflammed areas where most of the pain is
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realized. When blood flow is improved to an ailing joint, healing begins and
true pain relief is realized.
[0032] The compositions of the invention may include other plant
or
herbal extracts. For example, there may be utilized extracts of Paraguay tea,
Kola and Guarana which provide a source of methylxanthines, saponius,
tannins and glycosides which have been shown to reduce swelling and
redness. The extract of Paraguay tea is known as "Mate extract" and is
described in the "International Cosmetic Ingredient Dictionary", 5th Edition.
Mate extract is commercially available in combination with extracts of Kola
and Guarana which is sold by Cosmetic Ingredient Resources of Stamford
under the trademark "QUENCHT."
(0033] Suitable herbs which can be used also include symphytum,
officianalis, Moschus moscheferous, Cow bezoar, Pripalia geniculata,
Plantago asiatica, Causticum, Helianthemum canadense, Ornithogalum
umbellatum, Clematis crispa, Impatiens pallida, Prunus Cerasus, and the like.
[0034] The present invention will be more readily understood by
referring to the following examples which are given to illustrate the
invention
rather than to limit its scope. The amounts indicated are by weight percent
unless otherwise noted.
EXAMPLE 1
Cream to treat pain
(0035] A non-carcinogenic cream is prepared by admixing the
following
ingredients.
= 12.7% of a synergistic combination of emu oil, olive oil, argan nut oil,
sunflower/safflower oil and coconut oil;
= 15.8% of a synergistic combination of coleyl oleate and cetearyl
alcohol;
= 1.05% of a synergistic combination of glucose, glucose oxidase and
lactoperoxidase;
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= 65.67% of water and
= 4.78% of a combination of homeopathic extracts containing:
O 0.05 % by weight of pancreatinum,
O 0.01% by weight of ruta graveolens,
O 0.01% by weight of ledum palustre,
O 0.1% by weight of colchicum autumnale,
O 0.1% by weight of symphytum officinal's,
O 1.5% by weight of arnica montana,
O 0.5% by weight of atropa belladonna,
O 0.07% by weight of achillea millefolium,
O 0.45% by weight of hamamelis,
O 0.04% by weight of mercurius solubilis,
O 0.01% by weight of mercurius iodatus,
O 0.1% by weight of conium maculatum,
o 0.15% by weight of echinacea angustifolia,
O 0.15% by weight of echinacea purpurea,
O 0.5% by weight of aconitum napellus,
O 0.09% by weight of hypericum perforatum,
o 0.1% by weight of bellis perennis,
O 0.15% by weight of matricaria chamomilla,
O 0.45% by weight of calendula officinalis and
O 0.25% by weight of hepar sulphuris.
EXAMPLE 2
Cream to treat pain
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[0036] A non-
carcinogenic cream is prepared by admixing the following
ingredients.
= 14.7% of a synergistic combination of emu oil, olive oil, argon nut oil,
sunflower/safflower oil and coconut oil;
= 12.8% of a synergistic combination of oleyl oleate and cetearyl
alcohol;
= 1.05% of a synergistic combination of benzyl alcohol, salicylic acid,
glycerin and sorbic acid;
= 65.67% of water and
= 4.78% of a combination of homeopathic extracts containing:
O 0.05 % by weight of pancreatinum,
O 0.01% by weight of ruta graveolens,
o 0.01% by weight of ledum palustre,
O 0.1% by weight of colchicum autumnale,
O 0.1% by weight of symphytum offleinalis,
o 1.5% by weight of arnica montana,
O 0.5% by weight of atropa belladonna,
O 0.07% by weight of achillea millefolium,
= 0.45% by weight of hamamelis,
O 0.04% by weight of mercurius solubilis,
O 0.01% by weight of mercurius iodatus,
O 0.1% by weight of conium maculatum,
O 0.15% by weight of echinacea angustifolia,
O 0.15% by weight of echinacea purpurea,
O 0.5% by weight of aconitum napellus,
O 0.09% by weight of hypericum perforatum,
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O 0.1% by weight of bellis perennis,
o 0.15% by weight of matricaria chamomilla,
O 0.45% by weight of calendula officinalis and
O 0.25% by weight of hepar sulphuris.
While preferred embodiments have been described above and illustrated in
the accompanying drawings, it will be evident to those skilled in the art that
modifications may be made without departing from this disclosure. Such
modifications are considered as possible variants comprised in the scope of
the disclosure.
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