CONFECTION CONTAINING XYLITOL

PRODUIT CONTENANT DU XYLITOL

English Abstract

Abstract

The invention provides a novel chewable pressed
tablet containing xylitol and prepared by dry-blending
xylitol in an amount of from 10 to 80% by weight and a
polyol in an amount of from 10 to 80% by weight and
directly compressing the dry-blended admixture.

Claims

The embodiments of the invention in which an exclu-
sive property or privilege is claimed are defined as follows:


1. A dry-blended admixture directly compressed to
a chewable tablet, said tablet comprising xylitol in an amount
of from about 10 to about 80% by weight of the tablet and a
polyol in an amount of from about 10 to about 80% by weight,
said polyol being selected from the group consisting of sor-
bitol, mannitol, maltitol, hydrogenated starch hydrolysates
and mixtures thereof.


2. The tablet as defined in claim 1 wherein the
polyol is sorbitol, mannitol or mixtures thereof.


3. The tablet as defined in claim 1 further inclu-
ding a flavoring, coloring agent or mixtures thereof.


4. The tablet as defined in claim 1 further inclu-
ding a medicament dispersed therein.


5. The tablet as defined in claim 1 wherein the
xylitol is present in a weight ratio to the polyol of from
about 2:1 to about 1:2.


6. The tablet as defined in claim 2 comprising xyli-
tol in an amount of from about 20 to about 60% by weight and
sorbitol or mannitol in an amount of from about 20 to about
60% by weight.


7. The tablet as defined in claim 1 wherein the xyli-
tol is present in an amount of from 30 to about 60% by weight,
the polyol is sorbitol which is present in an amount of from
30 to 60% by weight, and further including flavoring in an amount
of from 0.01 to 2% by weight and a lubricant in an amount of
from 0.1 to 3% by weight.




8. Process for preparing a chewable compressed
tablet which comprises dry-blending xylitol in an amount
of from 10 to 80% by weight and a polyol in an amount of
from 10 to 80% by weight and directly compressing the dry-
blended mixture into a chewable tablet.
9. The process of claim 8 wherein the polyol is
sorbitol or mannitol.
10. The process of claim 8 which comprises dry-
blending xylitol, the polyol, a lubricant and a flavoring
agent and directly compressing the dry-blended mixture into
a chewable tablet.
11. The process of claim 8 which comprises dry-
blending xylitol, the polyol and a medicament and directly
compressing the dry-blended mixture into a chewable tablet.
12. The process of claim 8 wherein the xylitol is
present in a weight ratio to the polyol of from 2:1 to 1:2.
13. The process of claim 8 wherein xylitol in an
amount of from 20 to 60% by weight and sorbitol or mannitol
in an amount of from 20 to 60% by weight are dry-blended and
the dry-blended mixture directly compressed into a chewable
tablet.
14. The process of claim 8 wherein xylitol in an
amount of from 30 to 60% by weight, sorbitol in an amount of
from 30 to 60% by weight, flavoring in an amount of from 0.01
to 2% by weight and a lubricant in an amount of from 0.1 to
3% by weight are dry-blended and the dry-blended mixture
directly compressed into a chewable tablet.

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Description

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The present invention relates to a novel chewable
pressed tablet containing xylitol and one or more polyhydric
alcohols.
Xylitol is a natural sugar-alcohol known for its
use as a sugar substitute r particularly for children, because
it is non-cariogenic. Thus, xylitol has been employed as a
sugar-substitute in milk chocolate, chewing gum, ice cream,
gum-type candies, puddings, jams, jellies, marmalade and the
like.
It has also been suggested to use xylitol in pressed
tablets. Unfortunately, however, it has been found that
xylitol possesses very poor tablettlng characterist:Lcs and
there~ore compressed tablets containing the same have never
been satisfactorily produced.
The use of sorbitol as a sugar substitute in com- - -
pressed tablets is well known. However, the use of sorbitol
suffers from the drawback that it forms a very hard tablet
which may be too brittle or otherwise undesirable.
It has now been found that chewable pressed tablets
containing xylitol as a sugar substitute may be formed in an
efficient and economic manner by employing a polyol, such as
sorbitol, in combination with the xylitol. Surprisingly, the -
pressed tablet formed is softer than and has-improved texture
over con~entional pressed tablets containing sorbitol alone
as a sugar-substitute. While being harder than a tablet con-
taining xylitol alone, the xylitol tablet being too soft and
friable to have any practical use.
The present invention provides a dry-blended admixture
directly compressed to a chewable tablet, said tablet co]m-

prising xylitol in an amount of from about 10 to about 80%


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by weight of the tablet and a polyol in an amount o~ fromabout 10 to about 80~ by weight.
The present invention further provides a process for
preparing a chewable compressed tablet wh:ich comprises dry- -
blending xylitol in an amount of from 10 to 80~ by weight
and a polyol in an amount of from 10 to 80% by weight and
directly compressing the dry-blended mixture into a chewable
tablet.
The chewable pressed tablet or pressed mint-type
candy of the invention contains xylitol in an amount within
the range of from about 10 to about 80%, and preferably from
about 20 to about 60~ by weight of the tablet, and a polyol
in an amount within the range of ~rom about 10 to about 80%
and preferably ~rom about 20 to about 60% by weight of the
tablet. In addition, the tablet may include flavoring, color-


; .
ing agents, medicaments, preservatives and the like as will - -
be apparent to those skilled in the art.
The polyo~s suitable for use herein include, but are
not limited to, sorbitol, mannitol, maltitol and hydrogenated
starch hydrolysates, and combinations thereof, with sorbitol

,
being preferred.
In addition to the xylitol and polyol, the con~ection
o~ the invention may include synthetic sweeteners such as
sodium saccharin, calcium saccharin, dihydrochalcones, gly-
cyrrhizin, glycyrrhizic acid ammonium salt, L-aspartyl-L-
phenylalanine (methyl ester), as well as Stevia rebaudiana
(Stevioside), Richardella dulcifica (Miracle Berry), Dio-
scoreophyllum cumminsii (Serendipity Berry), cyclamates and

the like. `



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The confection in accordance with the invention may
also comprise flavoring agents in an amo~mt of from about
0.01 to about 10~ by weight and preferably ~rom about 0.2 to
about 0.25% by weight, e.g., oil of wintergreen, oil of
spearmint, oil of peppermint, clove oil, bay oil, anise oil,
eucalyptus oil, thyme oil, cedar leaf oil, cinnamon oil, oil
of nutmeg, oil of sage, oil of bitter almonds and cassia oil
and mixed ~ruit, natural and artificial fruit flavors such
as ascorbic acid, citric acid, lactic acid, adipic acid, malic
acid and tartaric acid, spice oils, etc. The con~ection may
also contain a tableting lubricant, ~uch as calcium stearate
or magnesium st0arate. Thu9, a pre~erred coneation o the
invention may have the following percentage o ingredients:


Xylitol 30-60%
Sorbitol 30-60%
Flavoring 0.01-2%
Lubricant 0.1-3%


The ~ollowing Examples represent pre~erred embodiments
o ~he present invention.
Example 1
Preparation of a Chewable Pressed-Mint Confection
... . _ ..

Parts by Weight


Xylitol 470
Sorbitol 470
Malic Acid 55
Magnesium stearate 18
Raspberry Flavor 4
FD&C Red #2 Lake Dye 0.4
FD&C Blue ~1 Lake Dye 0.04
.: :
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The above ingredients are blended thoroughly and
tabletted on a conventional tablet press.
When compared against control pre!3sed mints con-
taining no sorbitol or no xylitol, the mint of Example 1
is observed to have better texture, is softer and is more
readily compacted than are the control mints.
Example 2

Preparation of a Chewable Vitamin
- '

Parts by Weight

Xylitol 470
Sorbitol 470
~scorbic Acid 55
Magnesium stearate 18
Orange Flavor 5
FD&C Yellow #6 Lake Dye
The above ingredients are blended thoroughly and
tabletted on a conventional tablet press.
~ When compared against control chewable vitamins
con~aining no sorbitol or no xylitol, the chewable vitamin
o~ Example 2 is observed to have better texture, is softer
and is more readily compacted than are the co~trol vitamins.




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Example 3
Preparation of a Chewable Vitamin


Parts by Weight
'.

Xylitol 470
Mannitol 470
Ascorbic Acid 55
Magnesium stearate 18
Orange Flavor 5
FD&C Yellow #6 Lake Dye
The above ingredients are blended thoroughly and
tabletted on a conventional tablet press.
When compared against control chewable vitamins
containing no mannitol or no xylitol, the chewable vitamin
of Example 3 is observed to have better texture, is softer
and is more readily compacted than are the control vitamins.
Example 4
Preparation of a Chewable Aspirin
.
Parts by Weight
-~~~~

Powdered Aspirin 150

Sorbitol/Xylltol 597/256 "

~- Glycine ~ 20

Orange Flavor 7


Stearic Acid 20

FD&C Yellow #6 Lake Dye

The above ingredients are blended thQroughly and
:........ .. . .
tabletted on a conventional tablet press. ~
: . .
When compared against control chewable aspirin con-

taining no sorbitol or no xylitol, the chewable aspirin of
., '

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Example 4 is observed to have better texture, is softer and
is more readily compacted than are the control chewable
aspirins.
Example 5
,
Comparison of Pressed Mint Confections
. . _
Control A Control B

1000 parts xylitol 1000 parts sorbitol
4 parts peppermint oil 4 parts peppermint oil
10 parts magnesium 10 parts magnesium stearate
5 tearate

Composition of the Invention
. . _ . _ _ ,
500 parts xylitol
500 parts sorbitol
~ parts ~eppermint oil
10 parts magnesium stearate


The enclosed copy of the a~fidavit has not as ~et
been signed. However, a completed executed copy will be
forwarded to the Patent Office at the earliest possible time.
Each of the three above compositions was prepared by
dry-blending the various ingredients thereof and thereafter
directly compressing the dry-blended admixture into a tablet
using a conventional tablet press. The tablet in each case
was of the same weight and size (thickness). The results
obtained are as follows.
The Control A tablet containing only xylitol was
extremely friable, very soft and not capable o~ withstanding
; the slightest abuse, such as encountered during conventional

packaging procedures.
The Control B tablet containing sorbitol alone was not
sweet enough and was extremely hard and unsuitable as a chew-
able tablet.


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The inventive composition containing a combination
of xylitol and sorbitol had a pleasant sweet taste, was soft
enough to be of a chewable nature, but hard enough to with-
stand the normal amount of abuse received during a standard
packaging operation.




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