Note: Descriptions are shown in the official language in which they were submitted.
212288 ~ ~
Plant hyoiene disinfectant
The invent~on relates to the use of a plant
hygiene disinfectant according to the above patent
claims.
Plant hygiene disinfectants are sub~ect to ~.
reg~stration in the same way a~ are plant protection
agents, and are used for controling phytopdthogen~c fungL
and bacteria as well as viruse0 in horticultural opera~
I tions for regular and effective di~infection of selected
targets for the purpose of preventlng economic damage.
Plant hygiene disinfectants have hitherto con-
tained as active components phenol~, alcohol~, aldehydes,quaternary ammonLum compounds, amphoteric surfactants,
active-oxygen compound~, heavy metals and halogens; :.
however, the~e are either insufficiently effective, for
example alcohols, sodium hypochlorite and copper ~alt~
or have weakened effectiveness at a higher degree of
soiling, such as quaternary ammonium compounds. Because
of inadequate compatibillty with materials, active-
oxygen compounds and halogens are hardly used at all. ;~
Li~ewise aldehydes, for example glutaraldehyde and
especially formaldehyde are un~uitable owing to increas-
ing ecological and human toxicological consideration~
1 ; The quaternary ammonium compounds used at present
are ob~ected to by the registration authorities because
of their uncertain decomposition characteristics in the .. -
soil; halogenated phenols such as p-chloro-m-cresol are .. ~.
environmentally ob~ectlonable. ::~
~,.,,,..':
~ 2 2012288
The ob~ect of the inventlon i8 to provlde
disinfectant suitable for practical appllcation which i8
effective even in the pre~ence of organic and inorganlc
dirt, i~ reliable in use snd is environmentally friendly,
S offers advantage~ as regard~ toxicity to humans and to
the envlronment, nnd, flnally, 1~ comp~tible wLth plant~,
since in pr~ctice it comeo $nto contact with the plant,
for example, via spray watar or by ad~orptlon via the
vapor phase.
Accordingly, this ob~ect is achieved by the use
of a plant hygiene disinfectant as cl~imed in the main
cla~m, preferred embodiment~ being outlined in the
subclaims.
It has been shown that, surprisingly, a combina- ;
lS tion of .
A. a nsturally occurring phenol compound, in particular ~-~
. thymol, and
j ~. an aromatic alcohol, preferably phenoxyethanol, in
1 con~unction with
C. a wetting agent, preferably an alkyl bensenesulfon~
ate
provides a preparation which meets very well the above .
requirements, the certain volstility of the active :
1 substance being advantageous for the effectiveness of the :
novel agent, since the active substances in the vapor
phase penetrate the finest pores of the peat and sub~
str~te residues found in soiled areas. The excellent ; ~ :~
wetting act~on of the llquid disinfectants known hitherto
i8 clearly insufficient to penetrate these areas; the low ~; ~
-:
~ 3 ~ 20~2288
dlrt compo,tlbility of the non-volatlle quatern~ry com-
pounds lends support to this view. ;
The use according to the invention of the~e
mixtures offers con~idernble adv~ntages~ the subst,nces
S used a~ active substancea are n~turally occurring com-
pound~, which produce virtually no enviro,nmentally-
d,amaging residues, are env$ronment,~11y friendly and
biologically degrAdable and in ready-for-use dilution
constituts virtually no danger to plant~, humans and ~ -~
animals. The active substances pessess a volatility
which i8 eminently suit,~ble for disinfection in the field
of plant hygiene; on the one hand they are not too
volatile with the a~ociated risk of rapid 1088 of active
sub~tances from the ready-for-use solution, but on the
lS other hand they are volatil~a enough to provide effective
action in the proximity of the appllcation s$te via the
vapor phase,. ~ecause of their good compatibility with
plants, the risk of economic d,amage due to incorrect
application, long-term ,~ction or spr,~y cont,~ct i8
20 reduced. -~
The mixture is furthermcre in the form of a
concentrate and in ready-for-use dolution is virtually
odorless or has a pleas,ant odor. ~he solution is chemi- ;~
,~ . .
cally stable both as a concentrate and in ready-for-use
dilution and has a high flash point of more than lOO-C.
In addition, the combination of vegatable phenols
such ~8 thymol ,~nd nrom,~tic ,~lcohols such as, phenoxy- -~
ethanol i~ more effective thhn are the indivldual com- ~;
ponent~, and especially 80 in the presence of dirt; the j-
.... ~ . '
,, . j , ' ,ii ~ ! . :, . ~ '. ! ' . ... .
4 ~ 2 ~1 Z2
com~ination i8 thus ~uper~or to the known formulat~on~
ba~ed on quatern~ry ~mmonium compounds and more econo~i-
cally v~able on account of lt~ good effectlvene~ ~nd
comparatlvely low appllcatlon concentr~tion.
The composftion of the mixture u~ble accordlng
to the inventlon lle~ wlthln the followlng welght r~nge-~
A. phenolic compound 1 - 804, prefer~bly
; 5 - 40~, particularly
preferably 10 - 30%
B. aromstic alcohol 20 - g9~, prefar~bly
60 - 95~, particularly
preferably 70 - 90%
C. wetting agent or surfactant 0.1 - 15~, preferably
1 - 10~, particularly
preferably 2 - 8
The phenolic compounds are preferred in the
following order~ thymol, guaiacol, eugenol, carvacrol,
~alicyllc acid and lt~ salt~, methyl ~licylato, p-
cumaric acid, c~ffoic ~cid, ferulic acid, sinapic acid
and fin~lly ~180 sinapic ~lcohol.
The aromatic ~lcohols are prefer~bly used in the
: following orders phenoxyethanol, phenethyl ~lcohol,
benzyl alcohol, 2-phenoxypropan-1-ol and l-phenoxypropan-
2-ol prefer~bly as a mixture, 3-phenoxypropan-1-ol,
cinnamyl alcohol and finally also 2-phenylcyclohexanol.
Suitable wetting agents or surfactants are
~nionic surf~ctants, non-~nionic surfact~nts, quaternnry
~mmonium compounds, amphoteric surf~ct~nts or mixture~
thereof, ~lkyl benzenesulfon~tes, alkyl sulfates, alkyl
. ~
' . ,', i .'. `, . . . ~ . ' i
- s - ;~0122~38
sulfonates, fatty alcohol ether sulfates or mixture~
thereof being preferred.
The pH of the formulation ~ccordin~ to tho
invention ranges from pH 1 to pH 12 and may be ad~usted
by an appropriate addition of chemical~. To relnforce
the effectivene~s, ~n ~cid pH r~n~e 1~ Adv~ntngeou~,
while to improve cleansinq ~ction the alkaline pN range
is preferred.
The mixture~ may also contain customary additive~
such as other known bactericidal and fungicidal active
substances, corrosion inhibitor~, dyes, odorants, stabil~
izer~ as well as alkalis, acids and buffer salts for
ad~usting or stabilizing the pH of the concentrate and/or
.~. , ~,.~.,
of the ready-for-u~e solution, and additionally also
solvents, solubilizing agents, auxiliary substances for ~;
ad~ustinq viscosity, plant nutrients or insecticides.
In additlon to their wetting action, the surf~c-
tants also pos~ess good dispersing and emulsifying action
~nd have ~ benefici~l effect on the t~biliz~tlon of the
re~dy-for-u~e ~olutlon by counteracting tendency for
~ep~r~tion ~nd cry~t~lliz~tion. ~ ~
:,' ";.~.
I Example 1
` To establish microbiological potency against
phytopathogenic micro-organisms with or without loading,
the formulations given below were prep~red; of these, ~ -
formul~tlon A corre~ponds to the invention, while the
comparison formul~tlons B, ~, D and E contain in each
case one of the component~ required according to the
.. :: :,
... . .
. " "" ;I .i,; ;".. ~ ' r'` ;;i
: . - 6 -
invention. 2 O~ 22 88
Formul~tlons~
A B C D E
2-Phenoxy-
eth~nol 75 100 : ~ :
Thymol 20 20 20 ~.
Ethanol .80 80
Marlon A 350 5
NaOH, 45~ 15
H2O 20 65
The microbiological potency of the formulations
was tested according to the guidelines for the official
testing of plant treatment agents, 16-4 guidelines for
15testing plant protection agents for disinfection of
ornsmental plants (issued by the Federal Biological
Institute for Agriculture and ~orestry, Berlin and `-
Brunswick, April 1986); procedure ~ccording to Appendix
1, Laboratory Te~ting.
20The results are listed in the ttached Tables 1
to 4.
~ .
.
'
FR LRDRS PRRRY NY TO:1613232a440 ~RR 9~ 1990 11:40R~ ~041 P.02
~1 2ol2288
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` 11- 2012288
The result~ dhow th~t the comblnation phenoxy-
ethanol + thymol (mixture A) i~ more effective than the
individual components. The combinstion i8 a clear,
colorless liquid with a weak, characteristic, pleasant
odor.
The 0.5, 1 ~nd 2~ re~dy-for-uee solution in water
i8 highly compat~ble with plants both in the 90il ~nd in
the vapor phaee. The 0.5 to 2% ready-for-use solutions
in water are colorless, virtually clear to faintly milky,
- 10 have a neutral pH and are slightly foaming. The ready-
for-use solution $8 an effective cleaning agent, is
comparatively well tolerated by skin, iB heat stable and
,., .:
resistant ~o light.
Determination of oxygen consumption of cultivated
sewage sludge by the Warburg method (German standard
methods for water, effluent and sludge investiqation; L
2 and H 5, 1972) establi~hed that a 0.1~ solution of
formulation A L~ toxicologic~lly harmless to sewage
sludge.
The BOD~ value, determined ~rom the difference
between test ~olution And control, iB 1. 110 mg of
02/liter for the 0.01% solution of formula At i.e. the
0.01% solution acts a~ a ~ubstrate for the flora of the
sewage sludge and i~ oxidatively degraded. -;
The mixture used accordinq to the invention is
useful for controling all important phytopathogenic
micro-organisms, ~uch a~ Xanthomona~ perlargonii and
begonlao (oll ~pot- on polargonlu~- and b-gonla~
Erwlnla ~mylovora (flre bllght), Frwlnia carotovora
: ,. :
' " ;`'''; ' ` ' ! ~ ~
20~2288
2 --
(saintp~ul~as), ~rw~ni~ chry~nthemi (pot chry~anthe-
mums), Botrytis cinerea, Phytophtora, Pythium, Thlela-
viopsis bosicola, (cycl~men, poinsettias, begoni~
Yerticillium dahliae (pelargonium~, begonias), Cyllndro-
S cladium scoparium (eric~s ~nd az~leas)~ Cylindrocladium
parvum, Plasmodiophora brassicae (club root); long-lived
organi~ms such ~8 Botrytis scleroti~ and chl~mydospora,
Thiel~viop~ls and Fusar$um are kllled. Furthermore,
Asperqlllus nlger (mold), moss and algae ~re attacked.
The mixtures are employed in horticulture especi-
ally after preliminary cleaning treatment against
bacterial, fungal and viral phytopathogenic germs on
display surfaces, beet trouqh walls, cultivation ve sels
such as pots, plates or seed trays, greenhouse interior
surfaces, potting tables, substrate storage surfaces,
container store~, surfaces and installations in ~tore
rooms for plants and plant products, and on equipment
such as transport boxe~, service trolleys, wheelbarrows,
shovels and plant dibber~.
~ p~e 2
Mixtures con3isting of 75% by weight of phenoxy-
ethanol and 5% by weight of alkyl benzenesulfonate
! (Marlon A 350-~Wz)-) with other naturally occurring
phenols were prepared in amounts of 20% by weight in each
case as followss
Formulation Fs with guai~col
Formulation G~ with eugenol -
Formulation Ht with chlorothymol
2012288 -:
3 ~
The resultant values are li~ted in Table 5.
~0~2288
F~- LRDRS PRRRY NY TO:1613232P440 MRR 9~ 1990 11:42RM #041 P.06
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