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Patent 2097919 Summary

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(12) Patent Application: (11) CA 2097919
(54) English Title: JET INJECTOR FOR MASS INOCULATION
(54) French Title: PISTOLET A INJECTION POUR INOCULATION DE MASSE
Status: Dead
Bibliographic Data
(51) International Patent Classification (IPC):
  • A61M 5/307 (2006.01)
  • A61M 5/30 (2006.01)
  • A61M 5/20 (2006.01)
(72) Inventors :
  • ROSENZWEIG, PETER ELLIOTT (Australia)
(73) Owners :
  • COLUMBIA PACIFIC TECHNOLOGIES LIMITED (Australia)
(71) Applicants :
(74) Agent: NORTON ROSE FULBRIGHT CANADA LLP/S.E.N.C.R.L., S.R.L.
(74) Associate agent:
(45) Issued:
(86) PCT Filing Date: 1991-12-06
(87) Open to Public Inspection: 1992-06-25
Examination requested: 1998-12-07
Availability of licence: N/A
(25) Language of filing: English

Patent Cooperation Treaty (PCT): Yes
(86) PCT Filing Number: PCT/AU1991/000566
(87) International Publication Number: WO1992/010226
(85) National Entry: 1993-06-07

(30) Application Priority Data:
Application No. Country/Territory Date
PK 3801 Australia 1990-12-07

Abstracts

English Abstract



ABSTRACT

A needleless jet injector device (100) for
use with separate storage tanks of gas and
medicament, the device (100) comprising a body
having a gas inlet for connection to the gas storage
tank and a medicament inlet for connection to the
medicament storage tank, an active chamber for
receiving medicament and having a jet nozzle (1)
through which the medicament is discharged, the
active chamber further receiving a piston head (3)
movable to force the medicament through the nozzle
(1) upon movement of the piston head (3) in the
chamber towards the nozzle (1), the piston head (3)
being connected to a piston (9) movable within a gas
chamber (24) within the body, and means (14, 15, 20)
for selectively allowing gas to enter the gas
chamber (24) so as to move the piston (9) and the
piston head (3) to discharge medicament through the
nozzle (1).


Claims

Note: Claims are shown in the official language in which they were submitted.


WO 92/10226 - 5 - PCT/AU91/00566

CLAIMS

1. A needleless jet injector device for use with a supply of gas
under pressure and medicament, the device comprising a body having a gas
inlet for said gas and a medicament inlet for said medicament, a first
chamber communicating with said medicament inlet and having an outlet, a
jet nozzle communicating with said outlet so as to receive medicament,
under pressure, for injection, a second chamber communicating with said
gas inlet, a first piston at least partly defining said first chamber and
movable to vary the volume thereof so as to deliver a dose of medicament
under pressure to said outlet, a second piston at least partly defining
said second chamber and movable to vary the volume thereof, connection
means coupling the first and second pistons so that movement of said
second piston causes movement of said first piston, medicament flow
control means to operatively restrict flow of the medicament from the
medicament inlet to said first chamber, and control means to regulate the
flow of gas to said second chamber to cause movement of said second
piston and therefor movement of said first piston.
2. A needleless jet injector device according to claim 1, wherein
the medicament flow control means comprises a one way valve between the
first chamber and the nozzle to allow medicament to pass out from the
first chamber through the nozzle but to prevent air being drawn back into
the first chamber.
3. A needleless jet injector device according to either claim l
or claim 2, wherein said body is provide with a medicament storage
chamber coupled to receive medicament from the medicament inlet and an
outlet connected to the first chamber.
4. A needleless jet injector device according to claim 3, further
comprising a one way valve between the first chamber and the medicament
storage chamber to allow medicament to pass from the medicament storage
chamber to the first chamber but to prevent passage back into the
medicament storage chamber.
5. A needleless jet injector device according to any preceding
claim, wherein said body is provided with a gas storage chamber coupled
to receive gas from the gas inlet and an outlet connected to the second
chamber.

WO 92/10226 PCT/AU91/00566 - 6 -

6. A needleless jet injector device according to claim 5, wherein
said control means comprises a release valve between the second chamber
and the gas storage chamber to allow gas to pass from the gas storage
chamber of the second chamber.
7. A needleless jet injector device according to claim 6, further
comprising a trigger means for releasing the release valve upon actuation
of the trigger means.
8. A needleless jet injector device according to any preceding
claim, wherein the connection means is movable in a cylinder, the
cylinder being provided with a vent to atmosphere.
9. A needleless jet injector device according to any preceding
claim, further comprising means for adjusting the amount of travel of the
first and second pistons so as to thereby adjust the amount of medicament
discharged through the nozzle.
10. A needleless jet injector device according to claim 9, wherein
said means for adjusting comprises a movable collar arranged within the
second chamber against which collar the second piston abuts when at a
rearmost position of its stroke.
11. A needleless jet injector device according to claim 10,
wherein the collar is movable forwards and rearwards by means of a worm
screw arrangement to thereby move the first piston within the first
chamber to decrease or increase the volume of the first chamber and hence
the amount of medicament therein.
12. A combination of a needleless jet injector device according to
any preceding claim and a backpack containing a gas storage tank and a
medicament storage tank connected to the gas inlet and the medicament
inlet, respectively.
13. A combination according to claim 12, further comprising a
manifold between the gas storage tank and the gas inlet and the
medicament storage tank and the medicament inlet.
14. A combination according to either claim 12 or claim 13,
wherein the backpack is provided with a frame and straps for mounting the
backpack on a user.

Description

Note: Descriptions are shown in the official language in which they were submitted.


2~97~
W O 92~1022~ ~ . PCT/AU~1~00566

JET l 1QR QR ~S IN~C~LATION
BA~K~RQ~LND OF THE_LN.VENTION
The presen~ lnvention per~ains to needleless injectors and ~ore
particularly to a needleless ~e~ injector for mass lnoculation.
SUMMARY OF THE INVENl~LON
~t i5 ~n ob~ect of ~he present invention to provide ~ iet injector
which facilit~tes mass ad~inistration, by in~ection, of ~eterinary or
human ~edicat~on from a bulk supply.
Accordlngly, the ln~ention provides, in a first aspe~t, a
n~edleles5 Jet inje~t~r device ~or use with a supply of gas under
pressure and medlcament, th~ devlce comprist~g a body ha~tng a gas lnlet
for sai~ ~as and a medicament iniet ~o~ said medicament, a ~irst chambe~
communicatjng w~th said medicament inlet and havin~ an out1et, ~ jet
nozzle eommunicating wi~h said outlet so ~s to receive medtcament, under
pressur~, ~or ~njection, a second chamber communicatlng with said ~as
inle.~, a ~irst piston at least partly defining sald flrst cha~ber zn~
mova41e ~o vary the volume thereo~ so as to ~eliver a dose of medieament
und~r pressurQ ~o sa1d ou~l~k, a second piston ~t least partly de~tning
sald second ~h~mber and ~vable to ~ary the volume thereof, connection
means ~oupllng th~ first and second plstons so that movement of said
second plston causes movement of sai~ first piston, medicament flow
control means to operatively restrict flow of the medicamen~ ~rom the
medicament inlet to said ~rs~ chamber, and control me~ns to ~egulate the
flow o~ gas to said s~cond chamber to cause moYem~nt of sald second
pis~on ~nd therefor movement of said first pis~on.
In a preferred embodiment, the medication is carrled by a ~ckpac~
which suppll~s ~he ln~ector. The inj~c~or p~eferably au~omatically
r~l4ads a medication cylinder upon th~ releas~ of a trigg~r m2chanlsm at
the c~mpletlon of ~ch injection.
3~ It ts ~r~fPrr~d that tho do~ago bo roa~l ly ad justablo by me~n~ o~
piston st~ok~ ~djust2r.

One embo~ment of a jet injector accordin~ to the present ~nv~ntion
will now be moro fully describe~, ~y way ~f ex~mDle, with reference to
35 the draw1n~s~ of ~hi~h~
Floure 1 ~* A l~r-nes-s~tion~1 vi~w of ~n~ ~mbc~d~ ent Of A jet
in~ec~or d~cordtng to the present inventlon; ar~d


1 L610 nN 98bS19~ ~ 19 ~IOSn~`d~ OSn~dS 90 l1 ~661 ~In~ l

w 0 92~10~26 ~ 2 - 2 ~ 9 7 9 ~ 9

FigurQ Z is a perspeetiYe view of the injeetor o~ Flgure l and a
bac~pack used to carried ~e~icament and propellant.
DETAILED DESCRIPTION OF THE DRAhlIN~
As shown ln f1gure l, a nee~leless 3et injector lO0 eomprises a
noz~le l through which a high pressured je~ is discharged. Puring the
delivery stroke of a delivery piston 31 a check val~e 2 opens, allowlng
medicat~on to pass through the nozzle l. The check valve 2 closes on the
intake stroke o~ the plston 3 to prevent air from being drawn lnto the
interchangeable medieatlon cylinder 22. As the piston 3 re~iprocates,
medicat~on is al~ernately drawn into the ~ylin~er 22 ~nd ~lscharged
thro4gh the nozzle l.
A me~icatton transfer tube ~ enables medication to be ~ansferred
from a medl~ation receiver 6 to the med~cation cylinder 22. A check
valve 5 clo~es on the dQlivery s~roke o~ the piston 3 preYQnting
medication from passing back into ~he re~eiver 6. The eheck valve 5
opens on the ~ntake s~ro~e of ~he piston to allow medication to flow ~rom
the recetv0r 6 to the cYlinder 22. The medleat~on receiver 6 is a
~hamb~r ~thln the body o~ the injeCtor which receives and holds
medlcation fro~ an external soUrce such as a baekpack.
2~ To ensu~e that the rear port10n o~ the cyllnd~r ~ln ~hlch the
piston rod 8 resl~es~ is open ~o atmospher~c pressure during b~h intaka
and dell~ery stro~e~, a cylinder ven~ 7 ts provided throu~h the rear of
the mQdlcatlon cylin~er.
The piston rod ~ connec~s the delivery piston 3 to a ~2
pis~on 9. When a pressurlzed ~as such as C02 i~ released from ~he
C2 receiv~ng chamber 13 it passes through ~ ~2 release valve 14 (if
open) and tnto a C0z chamber 24. ~ collar st~p lO i5 provided ~n the
ch~mber 24 ~or limiting and ad~sting the retu~n stop position of the
p~ston 9. A ~orm and rack ~echanism ll respond~ to rotation o~ the
30 st~oke adiust~r 12, movlng the stop lO ~orward and backward in a linea~
~shion thereby altering the stroke o~ ~he plstQn 9.
The C02 release v~1ve 14 is opene~ by aetuation o~ ~he tr~er
and l~ver mechanism 20 actlng through ~he release valve actuator 15,
Opening the C02 rel~ase valYe 14 allows pressurized g~s to travel from
~5 ~hQ recelvlng ~hamber 13, lnt~ t~e delivery cha~ber 24 and hence lnto the
working portion of th~ cylinder 23 ~or the p~rpose or displacing the
plston 9.



g 1 1.610 N ~ I.q ~ n~ Nl~r~ n.ll ~fifi~ un~ l.

~o 92/~02~fi _ 3 _ 2 ~ ~ 7 9 ~ 9 PcrfA~9l/005~

A r~lease \lalve ac~ua~4r 15 is provide~ which~ upon upward
deflection of the trig~er and le~er ~echanism 20, opens the C02 release
valve 14 an~ closes the C02 cylinder vent Yalve 16. ~ith the trigger
an~ lever mechanism Z0 Stlll held in the upward deflected posltionl the
rele~se valve actuator lS allows the release valve 14 to ~lose, stopplng
the ~low o~ pressurized g~s lnto the delive~y ¢hamber 24 at the
completlon of ~he delivery st~oke.
The cyl~nde~ vent valve 16 ap~ns upon the rel~ase of the ~r~gger
and l?ver ~echanism ~0 and allows the cylinder Z3 ~o be vented to the
10 atmosphere via the cy1inder port 17, lever por~ 18 ~nd handle vent 19.
At the completion o~ the delivery stroke, a t~nsfer valve 21 opens
and allows pressvrized gas to fill the return chambe~ 2~. Upon release
o~ the tr~gger end lever mechanism 20 the cylinder ~ent ~ e ~6 opens
and the cyllnder 23 is vented ~o atmosphere ~hlch ln turn allows the
1~ pressu~lzed g~s in ~he return chamber 25 to drive the piston 9 back to
the collar stoP 10. With th~ return ~ravel o~ the plston 9, the piston 3
~raws medication into the ~edicatian cyllnder 22.
As sho~n in ~ig~re 2, a trlgger operated jet injec hr ne~teless
syrtn~e 100 according to the teach~ngs o~ the present inventi~n may be
~se~ ln con~U~ct~on with a ba~kp~ck harness 101. The harness 101 m~y be
used to support a medi~amen~ cytlnder 102 and a liquid carbon dioxide
cy71nder 103. The Con~ents of the medicament and C02 cylin~ers ~re
discharge~ through a manl~old 104 and through separate hoses 1~, 105 to
the respect~ve intake ports of the injector 100.
Z5 The backpack harness may consist of a ri~id mount~n~ frame which
includes wa~st and shoulder straps whieh can be ad~usted to the wearer~s
needs. The C02 and medtcament ~anifold(s~ may either be attached to
the harness or separately attached to Qach of the cyllnders.
The pressur ked gas cylinder, preferably a carbondlo~lde cyl~nder,
will 4e ~ high pressure c~linder containing approximately Z.5 kilo~rams
of llquid car~on dioxide which is used as ~he pressu~e medium for
~tuatin~ th~ plston 9.
The ~edicament ~yllnder may be an unpr~ssurized vessel of 1ight
hei~h~ material to contain ~he particular medicament use~ in a partic~lar
35 lnoculation program~ Like ~he pressurized gas cylinder lt ls readily
~eplacable and refillable.




1. ~ n ON q~C 1 ~7 7 l a Mf\Cn~TIT~ :~ AlrlCn~TrTC I n ' l T ~ n ,~ I

WO ~/10226 4 P~T~AII~1/005~6
- 2~7c~
Both the medicament cylinder 2~ and no~zle 1 of the iniecror 100
are replacable. The ~ylinder may be tailored to suit the cor~eCt ~age
o~ a particular medtcament. The noz~le contains a very fine bore whleh,
on release o~ the pts~on 4nder the gas p~essure, wi~l create a high
p~essure, high veloçlty ~et. The nat~re o~ the high veloci~y iet throush
the fine bore creates ~ear within the bore and after a perl~d of time,
thls wear ~ e~uce the efficiency of p~netration o~ the medicamen~.
The nozzle is ~he~e~ore readily replacable in the fiel~ at the first slgn
of r~du~ed ef~iciency which will be not~iç~ble by wetting of the skin
surface.
The ~njector portion 100 may b~ provlded in two or more sizes
utllising the same operating principles. A larger robust unit ts
par~te~larly su~ted to mass inoculation o~ sheepl cattl2, pi~s an~ other
animals, A s~aller ~nit is more suitable for the mass inoculation o~
~hlldren and adults.
A ~a~or benefit of this invention ls the fully auto~atlc reloading
~nd recha~ging for rapi~ multlpte injections. The unlt ls ~u11y
ad~ustable ln ~oth dosage and charge for diffQ~nce thickness s~lns and
~lfferent stzes o~ antmals. ~ecause it is a needleless syringe, tt
completely elimtnates ~he problem of cross contam~natlon or infectton
~hich exlsts w~h mass inoculation ~ith multiple u~e n~edles,
~ hlle the present ln~ention has been des~ribe~ w~h re~erenee to
parttc~lar mechantc~t ~o~ponents and detatls o~ ¢onstruction, these
should ~e understoo~ as having been provided by ~ay of example an~ not as
limt~atjon to the scope of the invention.




8 d l610 N 98~ ( % 1~ Nr)~n~ Nrl~n~i~ 2h l.~ 1 un~ 1

Representative Drawing
A single figure which represents the drawing illustrating the invention.
Administrative Status

For a clearer understanding of the status of the application/patent presented on this page, the site Disclaimer , as well as the definitions for Patent , Administrative Status , Maintenance Fee  and Payment History  should be consulted.

Administrative Status

Title Date
Forecasted Issue Date Unavailable
(86) PCT Filing Date 1991-12-06
(87) PCT Publication Date 1992-06-25
(85) National Entry 1993-06-07
Examination Requested 1998-12-07
Dead Application 2003-12-08

Abandonment History

Abandonment Date Reason Reinstatement Date
2000-12-06 FAILURE TO PAY APPLICATION MAINTENANCE FEE 2001-12-06
2001-12-06 FAILURE TO PAY APPLICATION MAINTENANCE FEE 2002-12-06
2002-12-06 FAILURE TO PAY APPLICATION MAINTENANCE FEE

Payment History

Fee Type Anniversary Year Due Date Amount Paid Paid Date
Application Fee $0.00 1993-06-07
Maintenance Fee - Application - New Act 2 1993-12-06 $100.00 1993-11-09
Registration of a document - section 124 $0.00 1994-03-11
Maintenance Fee - Application - New Act 3 1994-12-06 $100.00 1994-12-02
Maintenance Fee - Application - New Act 4 1995-12-06 $100.00 1995-11-23
Maintenance Fee - Application - New Act 5 1996-12-06 $150.00 1996-11-27
Maintenance Fee - Application - New Act 6 1997-12-08 $150.00 1997-11-21
Maintenance Fee - Application - New Act 7 1998-12-07 $150.00 1998-12-01
Request for Examination $400.00 1998-12-07
Registration of a document - section 124 $50.00 1999-01-14
Maintenance Fee - Application - New Act 8 1999-12-06 $150.00 1999-12-06
Reinstatement: Failure to Pay Application Maintenance Fees $200.00 2001-12-06
Maintenance Fee - Application - New Act 9 2000-12-06 $150.00 2001-12-06
Reinstatement: Failure to Pay Application Maintenance Fees $200.00 2002-12-06
Maintenance Fee - Application - New Act 10 2001-12-06 $200.00 2002-12-06
Owners on Record

Note: Records showing the ownership history in alphabetical order.

Current Owners on Record
COLUMBIA PACIFIC TECHNOLOGIES LIMITED
Past Owners on Record
ROSENZWEIG, PETER ELLIOTT
SY-QUEST INTERNATIONAL LIMITED
Past Owners that do not appear in the "Owners on Record" listing will appear in other documentation within the application.
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Document
Description 
Date
(yyyy-mm-dd) 
Number of pages   Size of Image (KB) 
Claims 1994-04-16 2 98
Representative Drawing 1999-10-05 1 42
Cover Page 1994-04-16 1 17
Abstract 1994-04-16 1 24
Drawings 1994-04-16 2 77
Description 1994-04-16 4 199
Correspondence 1999-02-25 1 2
Assignment 1999-01-14 15 673
Prosecution-Amendment 1998-12-07 2 58
PCT 1993-06-07 19 708
Assignment 1993-06-07 11 372
Fees 2002-12-06 1 46
Fees 2001-12-06 1 45
Fees 1996-11-27 1 43
Fees 1995-11-23 1 44
Fees 1994-12-02 1 46
Fees 1993-11-09 1 33