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Patent 2317050 Summary

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(12) Patent: (11) CA 2317050
(54) English Title: USE OF NEONICODINOIDS ON TRANSGENIC PLANTS
(54) French Title: UTILISATION DE NEONICOTINOIDES SUR DES PLANTES TRANSGENIQUES
Status: Expired
Bibliographic Data
(51) International Patent Classification (IPC):
  • A01N 51/00 (2006.01)
  • A01N 47/40 (2006.01)
(72) Inventors :
  • LEE, BRUCE (Germany)
  • SUTTER, MARIUS (Switzerland)
  • BUHOLZER, HUBERT (Switzerland)
(73) Owners :
  • SYNGENTA PARTICIPATIONS AG (Switzerland)
(71) Applicants :
  • NOVARTIS AG (Switzerland)
(74) Agent: FETHERSTONHAUGH & CO.
(74) Associate agent:
(45) Issued: 2008-06-10
(86) PCT Filing Date: 1999-01-14
(87) Open to Public Inspection: 1999-07-22
Examination requested: 2004-01-14
Availability of licence: N/A
(25) Language of filing: English

Patent Cooperation Treaty (PCT): Yes
(86) PCT Filing Number: PCT/EP1999/000183
(87) International Publication Number: WO1999/035913
(85) National Entry: 2000-06-27

(30) Application Priority Data:
Application No. Country/Territory Date
80/98 Switzerland 1998-01-16
706/98 Switzerland 1998-03-25

Abstracts

English Abstract




There is now described a method of controlling pests with nitroimino- or
nitroguanidino-compounds; more specifically a method of
controlling pests in and on transgenic crops of useful plants, such as, for
example, in crops of maize, cereals, soya beans, tomatoes, cotton,
potatoes, rice and mustard, with a nitroimino- or nitroguanidino-compound,
especially with thiamethoxam, characterized in that a pestical
composition comprising a nitroimino- or nitroguanidino- compound in free form
or in agrochemically useful salt form and at least one
auxiliary is applied to the pests or their environment, in particular to the
crop plant itself.


French Abstract

L'invention concerne un procédé de lutte antiparasitaire à l'aide de composés nitroimino ou nitroguanidino. Elle porte plus spécifiquement sur un procédé de lutte antiparasitaire dans et sur les cultures transgéniques de plantes utiles, comme par exemple, les cultures de maïs, de céréales, de germes de soja, de tomates, de coton, de pommes de terre, de riz et de moutarde, à l'aide d'un composé nitroimino ou nitroguanidino, en particulier du thiaméthoxame. Ledit procédé se caractérise en qu'il consiste à appliquer une composition pesticide comprenant un composé nitroimino ou nitroguanidino se présentant sous forme libre ou sous forme de sel utile en agrochimie, et au moins un auxiliaire, sur les parasites ou leur environnement, en particulier sur la plante cultivée elle-même.

Claims

Note: Claims are shown in the official language in which they were submitted.




-130-
CLAIMS:


1. A method of controlling pests in crops of
transgenic plants, wherein a pesticidal composition
comprising a nitroimino- or nitroguanidino-compound selected
from the group consisting of thiamethoxam, clothianidin and
thiacloprid as the active ingredient and at least one
auxiliary is applied to the pests or their environment.

2. The method according to claim 1, wherein the
nitroimino- or nitroguanidino-compound is thiamethoxam.
3. The method according to claim 1, wherein the
nitroimino- or nitroguanidino-compound is clothianidin.
4. The method according to claim 1, wherein the
nitroimino- or nitroguanidino-compound is thiacloprid.

5. The method according to any one of claims 1 to 4,
wherein the transgenic plant or propagation material thereof
is treated.

6. The method according to any one of claims 1 to 5,
wherein the crop of transgenic plants is maize.

7. The method according to any one of claims 1 to 5,
wherein the crop of transgenic plants is soya beans.

8. The method according to claim 5, wherein the
propagation material of the transgenic plant is treated.

Description

Note: Descriptions are shown in the official language in which they were submitted.



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USE OF NEONICODINOIDS ON TRANSGENIC PLANTS

The present invention relates to a method of oontrolling pests with a
nitroimino- or
nitroguanidino-compound, especially thiamethoxam; more specifically to a novel
method of
controlling pests in and on transgenic crops of useful plants with a
nitroimino- or
nitroguanidino-compound.

Certain pest control methods are proposed in the iitereture. However, these
mettiods are
not fully satisfactory in the field of pest control, which is why there is a
demand for providing
further methods for controlling and combating pests, in particular insects and
repre-
sentatives of the order Acarina, or for protecting plants, especially crop
plants. This object is
achieved according to the invention by providing the present method.

The present invention therefore relates to a method of controlling pests in
crops of
transgenic useful plants, such as, for example, in crops of maize, cereals,
soya beans,
tomatoes, cotton, potatoes, rice and mustard, characterized in that a
pesticidal composition
comprising a nitroimino- or nitroguanidino-compound, especially thiamethoxam,
imidacloprid, Ti-435 or thiacioprid in tree form or in agrochemically useful
salt form and at
least one auxiliary is applied to the pests or their environment, in
particular to the crop plant
itsetf; to the use of the composition In question and to propagation material
of transgenic
plants which has been treated with it.

Surprisingly, it has now emerged that the use of a nitroimino- or
nitroguanidino-compound
compound for controlling pests on transgenic' useful plants which contain -
for instance -
one or more genes expressing a pesticidally, particularly insecticidally,
acaricidally,
nematocidally or fugicidally active ingredient, or which are tolerant against
herbicides or
resistent against the attack of fungi, has a synergistic effect. It is highly
surprising that the
use of a nitroimino- or nitroguanidino-compound in combination with a
transgenic plant
exceeds the additive effect, to be expected in principle, on the pests to be
controlled and
thus extends the range of action of the nitroimino- or nitroguanidino-compound
and of the
active principle expressed by the transgenic plant in particular in two
respects:

In particular, it has been found, surprisingly, that wjthin the scope of
invention the pesticidal
activity of a nitroimino- or nitroguanidino-compound in combination with the
effect
expressed by the transgenic useful plant, is not only additive in comparison
with the
pesticidal activities of the nitroimino- or nitroguanidino-compound alone and
of the


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transgenic crop plant alone, as can generally be expected, but that a
synergistic effect is
present. The term "synergistic", however, Is in no way to be understood in
this connecaon
as being restricted to the pesticidal activity, but the term also refers to
other advantageous
properties of the method according to the invention compared with the
nitroimino- or
nitroguanidino-compound and the transgenic useful plant alone. Examples of
such
advantageous properties which may be mentioned are: extension of the
pesticidal spectrum
of action to other pests, for example to resistant strains; reduction in the
application rate of
the nitroimino- or nitroguanidino-compound, or sufficient control of the pests
with the aid of
the compositions according to the invention even at an application rate of the
nitroimino- or
nitroguanidino-compound alone and the transgenic useful plant alone are
entirely
ineffective; enhanced crop safety; improved quality of produce such as higher
content of
nutrient or oil, better fiber quality, enhanced shelf life, reduced content of
toxic products
such as mycotoxins, reduced content of residues or unfavorable constituents of
any kind or
better digestability; improved tolerance to unfavorable temperatures, draughts
or salt
content of water; enhanced assimilation rates such as riutrient uptake, water
uptake and
photosynthesis; favorable crop properties such as altered leaf aerea, reduced
vegetative
growth, increased yields, favorable seed shape/seed thickness or germination
properties,
altered colonialisation by saprophytes or epiphytes, reduction of senescense,
improved
phytoalexin production, improved of accelerated ripening, flower set increase,
reduced boll
fall and shattering, better attraction to beneficials and predators, increased
pollination,
reduced attraction to birds; or other advantages known to those skilled in the
art.

Nitroimino- and nitroguanidino-cpmpounds, such as thiamethoxam (5-(2-
Chlorthiazol-5-
ylmethyl)-3-methyl-4-nitroimino-perhydro-1,3,5-oxadiazin), are known from EP-A-
O'580'553.
Within the scope of invention thiamethoxam is preferred.

Also preferred within the scope of invention is imidacloprid of the formula
CI

N N~N, H , known from The Pesticide Manual, 10"'Ed. (1991), The
N~,
NO2
British Crop Protection Council, London, page 591;


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-3-
also also preferred is Thiacloprid of the formula N~ N S , known from
I I
N, CN
EP-A-235'725;

CI

S
also preferred is the compound of the formula N H CH3 , known as
N N,
Y H
INI NO2
N~

Ti-435 (Clothiamidin) from EP-A-376'279

The agrochemically compatible salts of the nitroimino- or nitroguanidino-
compounds are, for
example, acid addition salts of inorganic and organic acids, in particular of
hydrochloric
acid, hydrobromic acid, sulfuric acid, nitric acid, perchioric acid,
phosphoric acid, formic
acid, acetic acid, trifluoroacetic acid, oxalic acid, malonic acid,
toluenesulfonic acid or
benzoic acid. Preferred within the scope of the present invention is a
composition known
per se which comprises, as active ingredient, thiamethoxam and imidacloprid,
each in the
free form, especially thiamethoxam.

The transgenic plants used according to the invention are plants, or
propagation material
thereof, which are transformed by means of recombinant DNA technology in such
a way
that they are - for instance - capable of synthesizing selectively acting
toxins as are known,
for example, from toxin-producinginvertebrates, especially of the phylum
Arthropoda, as can
be obtained from Bacillus thuringiensis strains; or as are known from plants,
such as lectins;
or in the alternative capable of expressing a herbicidal or fungicidal
resistance. Examples of
such toxins, or transgenic plants which are capable of synthesizing such
toxins, have been
disclosed, for example, in EP-A-O 374 753, WO 93/07278, WO 95/34656, EP-A-0
427 529
and EP-A-451 878.

The methods for generating such transgenic plants are widely known to those
skilled in the
art and described, for example, in the publications mentioned above.


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The toxins which can be expressed by such transgenic plants indude, for
example, toxins,
such as proteins which have insecticidal properties and which are expressed by
transgenic
plants, for example Bacillus cereus proteins or Bacillus popliae proteins; or
Bacillus
thuringiensis endotoxins (B.t.), such as CrylA(a), CrylA(b), CrylA(c), CryllA,
CryltlA, CryIIlB2
orCytA; VIP1; VIP2; VIP3; or insecticidal proteins of bacteria colonising
nematodes like
Photorhabdus spp or Xenorhabdus spp such as Photorhabdus luminescens,
Xenorhabdus
nematophilus etc.; proteinas6 inhibitors, such as trypsin inhibitors, serine
protease
inhibitors, patatin, cystatin, papain inhibitors; ribosome-inactivvating
proteins (RIP), such as
ricin, maize RIP, abrin, luffin, saporin or bryodin; plant lectins such as pea
lectins, barley
lectins or snowdrop lectins; or agglutinins; toxins produced by animals, such
as scorpion
toxins, spider venoms, wasp venoms and other insect-specific neurotoxins;
steroid
metabolism enzymes, such as 3-hydroxysteroid oxidase, ecdysteroid UDP-glycosyl
transferase, cholesterol oxidases, ecdysone inhibitors, HMG-COAreductase, ion
channel
blockers such as sodium and calcium, juvenile hormone esterase, diuretic
hormone
receptors, stilbene synthase, bibenzyl synthase, chitinases and glucanases.

Examples of known transgenic plants which comprise one or more genes which
encode
insecticidal resistance and express one or more toxins are the foilowing:
KnockOut
(maize), YieldGard (maize); NuCOTN 33B (cotton), Bollgard(t (cotton),
NewLeaf
(potatoes), NatureGard and Protecta .

The following tables comprise further examples of targets and principles and
crop
phenotypes of transgenic crops which show tolerance against pests mainly
insects, mites,
nematodes, virus, bacteria and diseases or are tolerant to specific herbicides
or classes of
herbicides.

Table Al: Crop: Maize

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones


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Effected target or expressed principle(s) Crop phenotype / Toierance to
Hydroxyphenyipyruvate dioxygenase isoxazofes such as tsoxafiutol or
(HPPD) isoxachiortoi, Triones such as
mesotrione or suicotrione
Phosphinothricin acetyl transferase Phosphinothftn
0-Methyl transferase altered lignin levels
Giutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) tnhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enoipyruvyi-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or suffosate
Protoporphyrinogen oxidase (PROTOX) Diphenyiethers, cyclic imides,
phenyipyrazoies, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as
Sulfonyiureas
Dimboa biosynthesis (Bxl gene) Helminthosporium turcicum,
Rhopalosiphum maydis, Diplodia
maydis, Ostrinia nubilalis, lepidoptera sp.
CMIII (small basic maize seed peptide plant pathogenes eg. fusarium,
aitemaria, scterotina
Com- SAFP (zeamatin) plant pathogenes eg. fusarium,
altemaria, sclerotina, rhizoctonia,
chaetomium,phycomyces
Hml gene Cochliobulus
Chitinases plant pathogenes
Glucanases plant pathogenes
Coat proteins viruses such as maize dwarf mosaic


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Effected target or expressed principie(s) Crop phenotype / Toleran+re to

virus, maize chiorotic dwarf virus
Bacillus thuringiensis toxins, VIP 3, iepidoptera, coieoptera, diptera,
Bacillus cereus toxins, Photorabdus and nematodes, eg. ostrinia nubilaiis,
Xenorhabdus toxins heiiothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., black cuiworm, asian com
borer,weeviis
3- Hydroxysteroid oxidase iepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., black cutworm, asian com
borer, weevils
Peroxidase lepidoptera, coieoptera, diptera,
nematodes, eg. ostrinia nubilatis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., black cutworm, asian com
borer, weevils
Aminopeptidase inhibitors eg. Leucine lepidoptera, coieoptera, diptera,
aminopeptidase inhibitor (LAPI) nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., black cutworm, asian com
borer, weevils
Limonene synthase com rootworms
Lectines lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., biack cutworm, asian com
borer, weevils


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Protease Inhibitors eg. cystatin, patatin, weevils, com rootwomn
virgiferin, CPTI
ribosome inactivating protein lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
hellothis zea, armywomns eg.
spodop=.era frugiperda, com rootworms,
sesamia sp., black cutworm, asian com
borer, weevils
maize 5C9 polypeptide lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., black cutworm, asian com
borer, weevils
HMG-CoA reductase lepidoptera, coieoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., black cutworm, asian com
borer, weevils

Table A2: Crop Wheat

Effected target or expressed principle(s) Crop phenotype / Toierance to
Acetolactate synthase (ALS) Sulfonylureas, lmidazoiinones,
Triazoiopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxafiutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione


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Effected target or expressed principie(s) Crop phenotype / Tolerance to
Phosphinothricin acetyl transferase Phosphinothrkin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase inhibitors of adenytosuccinate synthesis
Anthranitate Synttt.:se inhibitors of tryptophan synthesis and
catabolism
Nitritase 3,5-dihaio-4-hydroxy-benzonitriies such
as Bromoxynil and loxinyl
5-Enoipyruvyi-3phosphoshikimate Glyphosate or suifosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenyipyrazoies, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 Xenobiotics and herbicides such as
Sulfonyiureas
Antifungal polypeptide AIyAFP plant pathogenes eg septoria and
fusarioum
glucose oxidase plant pathogenes eg. fusarium, septoria
pyrroinitrin synthesis genes plant pathogenes eg. fusarium, septoria
serine/threonine kinases plant pathogenes eg. fusarium, septoria
and other diseases
Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria
polypeptide and other diseases
Systemic acquires resistance (SAR) viral, bacteriai, fungal, nematodal
genes pathogens
Chitinases plant pathogenes
Glucanases plant pathogenes
double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, iepidoptera, coleoptera, diptera,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Bacillus cereus toxins, Photorabdus and nematodes,
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, coieoptera, diptera,
nematodes,
Peroxidase lepidoptera, coieoptera, diptera,
nematodes,
Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, diptera,
aminopeptidase inhibitor nematodes,
Lectines lepidoptera, coleoptera, diptera,
nematodes, aphids
Protease Inhibitors eg. cystatin, patatin, lepidoptera, coleoptera, diptera,
virgiferin, CPTI nematodes, aphids
ribosome inactivating protein lepidoptera, coleoptera, diptera,
nematodes, aphids
HMG-CoA reductase lepidoptera, coleoptera, diptera,
nematodes, eg. ostrinia nubilalis,
heliothis zea, armyworms eg.
spodoptera frugiperda, com rootworms,
sesamia sp., black cutworm, asian com
borer, weevils

Table A3: Crop Barley

Effected target or expressed principle(s) Crop phenotype I Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazoiinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transfemse attered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
ATdhranilsa-a Synthase lnhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sutfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenyfpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SUI Xenobiotics and herbicides such as
Sulfonylureas
Antifungal polypeptide AIyAFP plant pathogenes eg septoria and
fusarioum
glucose oxidase plant pathogenes eg. fusarium, septoria
pyrroinitrin synthesis genes plant pathogenes eg. fusarium, septoria
serine/threonine kinases plant pathogenes eg. fusarium, septoria
and other diseases
Hypersensitive response eliciting plant pathogenes eg. fusarium, septoria
polypeptide and other diseases
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases plant pathogenes
Glucanases plant pathogenes
double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins viruses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, coieoptera, diptera,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Bacillus cereus toxins, Photorabdus and nematodes,
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, coleoptera, diptera,
nematodes,
Peroxidase lepidoptera, coleoptera, diptera,
nematodes,
Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, diptera,
aminopeptidase inhibitor nematodes,
Lectines lepidoptera, coleoptera, diptera,
nematodes, aphids
Protease Inhibitors eg. cystatin, patatin, lepidoptera, coleoptera, diptera,
virgiferin, CPTI nematodes, aphids
ribosome inactivating protein iepidoptera, coleoptera, diptera,
nematodes, aphids
HMG-CoA reductase lepidoptera, co{eoptera, diptera,
nematodes, aphids

Table A4: Crop Rice

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sutfonylureas, lmidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenyfpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Adenyiosuccinate Synthase inhlbitors of adenyiosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitdlase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvy!-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenyfethers, cyclic imides,
phenyipyn3zoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SUI Xenobiotics and herbicides such as
Sulfonylureas
Antifungal polypeptide AIyAFP plant pathogenes
glucose oxidase plant pathogenes
pyrroinitrin synthesis genes plant pathogenes
serine/threonine kinases plant pathogenes
Phenylaianine ammonia lyase (PAL) plant pathogenes eg bacterial leaf blight
and rice blast, inducible
phytoalexins plant pathogenes eg bacterial leaf blight
and rice blast
B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight
and rice blast
receptor kinase plant pathogenes eg bacterial leaf blight
and rice blast
Hypersensitive response eliciting plant pathogenes
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases plant pathogenes eg bacterial leaf blight
and rice blast
Glucanases plant pathogenes


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-13-
Effected target or expressed principle(s) Crop phenotype / Tolemnce to

double stranded ribonuclease viruses such as BYDV and MSMV
Coat proteins vinlses such as BYDV and MSMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera eg. stemborer, coleoptera eg
Bacillus cereus toxins, Photorabdus and rice water weevil, diptera, rice
hoppers
Xenorhabdus toxins eg brown rice hopper
3- Hydroxyrteroid oxidase lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper
Peroxidase iepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper
Aminopeptidase inhibitors eg. Leucine lepidoptera eg. stemborer; coleoptera eg
aminopeptidase inhibitor rice water weevil, diptera, rice hoppers
eg brown rice hopper
Lectines lepidoptera eg. stemborer, coieoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper

Protease Inhibitors, iepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper
ribosome inactivating protein lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper
HMG-CoA reductase lepidoptera eg. stemborer, coleoptera eg
rice water weevil, diptera, rice hoppers
eg brown rice hopper

Table A5: Crop Soya

Effected target or expressed principle(s) Crop phenotype / Toierance to


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Effected target or expressed principie(s) Crop phenotype / Toieranoe to

Acetolactate synthase (ALS) Sulfonyiureas, Imidazoiinones,
Triazotopyrimidines,
Pyrimidyioxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyaikanecarboxyiic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as tsoxatiutol or
(HPPD) Isoxachlortoi, Triones such as
mesotrione or suicotrione
Phosphinothricin acetyl transfen3se Phosphinothricin
0-Methyl transf erase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihato-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enoipyruvyi-3phosphoshikimate Giyphosate or sulfosate
Synthase (EPSPS)
Gtyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenytpyrazoies, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
setection Suifonyiureas
Antifungat polypeptide AIyAFP bacterial and fungal pathogens such as
fusarium, scterotinia, stemrot
oxalate oxidase bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
glucose oxidase bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
pyrrolnitrin synthesis genes bacterial and fungal pathogens such as


CA 02317050 2000-06-27

WO 99/35913 PCT/I:P99/00183
-15-
Effected target or expressed principte(s) Crop phenotype / Toleranos to

fusarium, scierotinia, stemrot
serine/threonine kinases bacterial and fungal pathogens such as
fusarium, sderotinia, stemrot
Phenytaianine ammonia lyase (PAL) bacterial and fungal pathogens such as
fusarium, sderotinia, stemrot
phytoaiexins plant pathogenes eg bacterisl leaf blight
and rice blast
B-1,3-glucanase antisense plant pathogenes eg bacterial leaf blight
and rice blast
receptor kinase bacterial and fungal pathogens such as
fusarium, sclerotinia, stemrot
Hypersensitive response eliciting plant pathogenes
poiypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens such as
fusarium, sderotinia, stemrot
Glucanases bacterial and fungal pathogens such as
fusarium, scierotinia, stemrot
double stranded ribonuclease viruses such as BPMV and SbMV
Coat proteins viruses such as BYDV and MSMV
Bacilius thuringiensis toxins, VIP 3, lepidoptera, coleoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, coleoptera, aphids
Peroxidase lepidoptera, coleoptera, aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, coleoptera, aphids
aminopeptidase inhibitor
Lectines lepidoptera, coleoptera, aphids
Protease Inhibitors eg virgiferin lepidoptera, coleoptera, aphids


CA 02317050 2000-06-27

WO 9955913 PCT/EP99/00183
-16-

Effected target or expressed principle(s) Crop phenotype / Tolerance to
ribosome inactivating protein lepidoptera, coleoptera, aphids
HMG-CoA reductase lepidoptera, coleoptera, aphids

Bamase nematodes eg root knot nematodes and
cyst nematodes
Cyst nematode hatching stimulus cyst nematodes
Antifeeding principles nematodes eg root knot nematodes and
cyst nematodes

Table A6: Crop Potatoes

Effected target or expressed principle(s) Crop phenotype ! Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase isoxazoles such as isoxafiutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)


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Effected target or expressed principie(s) Crop phenotype / Toierance to

Giypnosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derrvatives,
phenopyiate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sultonytureas
Polyphenol oxidase or Polyphenol blackspot bnjise
oxidase antisense
Metallothionein bacterial and fungal pathogens such as
phytophtora
Ribonuciease Phytophtora, Verticiliium, Rhizoctonia
Antifungat polypeptide AIyAFP bacterial and fungal pathogens such as
phytophtora
oxalate oxidase bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
glucose oxidase bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
pyrrotnitrin synthesis genes bacterial and fungal pathogens such as
Phytophtora, Verticiilium, Rhizoctonia
serine/threonine kinases bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
Cecropin B bacteria such as corynebacterium
sepedonicum, Erwinia carotovora
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
phytoalexins bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
B-1,3-gtucanase antisense bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
receptor kinase bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
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Effected target or expressed principie(s) Crop phenotype I Toierance to

Hypersensitive response eliciting bacterial and fungai pathogens such as
polypeptide Phytophtora, Veraciliium, Rhizoctonia
Systemic acquires resistance (SAR) virai, bacterial, fungai, nematodai
genes pathogens
Chitinases bacterial and fungal pathogens such as
Phytophtora, Verticiiiium, Rhizocionia
Bamase bacterial and fungal pathogens such as
Phytophtora, Verticiiiium,
Rhizoctonia
Disease resistance response gene 49 bacteriai and fungal pathogens such as
Phytophtora, Verticillium,
Rhizoctonia
trans aldolase antisense blackspots
Glucanases bacterial and fungal pathogens such as
Phytophtora, Verticillium, Rhizoctonia
double stranded ribonuciease viruses such as PLRV, PVY and TRV
Coat proteins vinises such as PLRV, PVY and TRV
17kDa or 60 kDa protein viruses such as PLRV, PVY and TRV
Nuclear inclusion proteins eg. a or b viruses such as PLRV, PVY and TRV
Pseudoubiquitin viruses such as PLRV, PVY and TRV
Replicase viruses such as PLRV, PVY and TRV
Bacillus thuringiensis toxins, VIP 3, coieoptera eg colorado potato beetle,
Bacillus cereus toxins, Photorabdus and aphids
Xenorhabdus toxins
3- Hydroxysteroid oxidase coleoptera eg colorado potato beetle,
aphids
Peroxidase coleoptera eg coiorado potato beetle,
aphids
Aminopeptidase inhibitors eg. Leucine coleoptera eg colorado potato beetle,
aminopeptidase inhibitor aphids
stilbene synthase coleoptera eg colorado potato beetle,
aphids


CA 02317050 2000-06-27

WO 99/35913 PCT/EP"/00183
-19-
Effected target or expressed principie(s) Crop phenotype / Toierance to

Lectines coleoptera eg colorado potato beetle,
aphids
Protease Inhibitors eg cystatin, patatin coleoptera eg colorado potato beetle,
aphids
rbosome inactivating protein coleoptera eg coiorado potato beetle,
aphids
HMG-CoA reductase coleoptera eg colorado potato beetle,
aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
Antifeeding principles nematodes eg root knot nematodes and
cyst nematodes

Table A7:.Crop Tomatoes

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) lsoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transf erase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
-20-
Effected target or expressed principle(s) Crop phenotype / Tolerance to

catabolism
Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such
as Bromoxynii and loxinyl
5-Enoipyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosete
Protoporphyrinogen oxidase (PROTOX) Diphenyiethers, cyclic imides,
phenyipyrazoies, pyridin derivatives,
phenopyiate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonyiureas
Polyphenol oxidase or Polyphenol blackspot bruise
oxidase antisense
Metallothionein bacterial and fungal pathogens such as
phytophtora
Ribonuclease Phytophtora, Verticillium, Rhizoctonia
Antifungal polypeptide AiyAFP bacteriai and fungal pathogens such as
bacteriai speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.

oxalate oxidase bacterial and fungal pathogens such as
bacteriai speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
glucose oxidase bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
pyrroinitrin synthesis genes bacteriai and fungal pathogens such as
bacteriai speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould


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WO 99/35913 PCT/EP99M1S3
-21 -

Effected target or expressed principle(s) Crop phenotype / Tolerance to
etc.
serine/threonine kinases bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery miidew, crown rot, leaf mould
etc.
Cecropin B bacterial and fungai pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 leaf mould
Osmotin aitemaria solani
Alpha Hordothionin bacteria
Systemin bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Poiygalacturonase inhibitors bacterial and fungal pathogens such as
bacteriai speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Prf regulatory gene bacterial and fungal pathogens such as
bacteriai speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
12 Fusarium resistance locus fusarium
phytoalexins bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould


CA 02317050 2000-06-27

WO 9955913 PCT/EP99/00183
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Effected target or expressed principle(s) Crop phenotype / Tolerance to

etc.
B-1,3-giucanase antisense bacteriai and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
receptor kinase bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Hypersensitive response eliciting bacterial and fungal pathogens such as
polypeptide bacteriai speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Systemic acquires resistance (SAR) virai, bacterial, fungal, nematodal
geries pathogens
Chitinases bacterial and fungal pathogens such as
bacterial speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
Bamase bacteriai and fungal pathogens such as
bacterial speck, fusarium, soft
rot, powdery mildew, crown rot,
leaf mould etc.
Glucanases bacterial and fungal pathogens such as
bacteriai speck, fusarium, soft rot,
powdery mildew, crown rot, leaf mould
etc.
double stranded ribonuciease viruses such as PLRV, PVY and ToMoV
Coat proteins viruses such as PLRV, PVY and ToMoV
17kDa or 60 kDa protein viruses such as PLRV, PVY and ToMoV
Nuclear inclusion proteins eg. a or b or viruses such as PLRV, PVY and ToMoV


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WO 99/35913 PCT~~~193
-23-
Effected target or expressed principle(s) Crop phenotype / Tolerancx3 to

Nucleoprotein TRV
Pseudoubiquitin vinises such as PLRV, PVY and ToMoV
Replicase viruses such as PLRV, PVY and ToMoV
Bacillus thuringiensis toxins, VIP 3, lepidoptera eg heliothis, whiteflies
Bacillus cereus toxins, Photorabdus and aphids
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera eg heliothis, whitefties
aphids
Peroxidase lepidoptera eg heliothis, whiteflies
aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera eg heliothis, whiteflies
aminopeptidase inhibitor aphids
Lectines lepidoptera eg heliothis, whiteflies
aphids
Protease Inhibitors eg cystatin, patatin lepidoptera eg heliothis, whiteflies
aphids
ribosome inactivating protein lepidoptera eg heliothis, whiteflies
aphids
stilbene synthase lepidoptera eg heliothis, whitefties
aphids
HMG-CoA reductase lepidoptera eg heliothis, whiteflies
aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
Antifeeding principles nematodes eg root knot nematodes and
cyst nematodes

Table AB: Crop Peppers

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, lmidazolinones,


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WO 99/35913 PCT/EP99/00183
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Effected target or expressed principie(s) Crop phenotype / Tolerance to
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered iignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitrifes such
as Bromoxynil and loxinyl
5-Enotpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
seiection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens
oxidase antisense
Metallothionein bacterial and fungal pathogens
Ribonuclease bacterial and fungal pathogens
Antifungal polypeptide AIyAFP bacterial and fungal pathogens
oxalate oxidase bacterial and fungal pathogens
glucose oxidase bacterial and fungal pathogens
pyrroinitrin synthesis genes bacterial and fungal pathogens


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WO 99/35913 PCT/EP99/00183
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Effected target or expressed principle(s) Crop phenotype / Tolerance to
serine/threonine kinases bacterial and fungal pathogens
Cecropin B bacterial and fungal pathogens rot, leaf
mould etc.

Phenylaianine ammonia lyase (PAL) bacteriai and fungal pathogens
Cf genes eg. Cf 9 Ct5 C4 Cf2 bacteriai and fungai pathogens
Osmotin bacterial and fungal pathogens
Alpha Hordothionin bacterial and fungal pathogens
Systemin bacterial and fungal pathogens
Polygalacturonase inhibitors bacterial and fungal pathogens
Prf regulatory gene bacterial and fungal pathogens
12 Fusarium resistance locus fusarium
phytoalexins bacterial and fungal pathogens
B-1,3-glucanase antisense bacterial and fungal pathogens
receptor kinase bacterial and fungal pathogens
Hypersensitive response eliciting bacterial and fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens
Bamase bacterial and fungal pathogens
Glucanases bacterial and fungal pathogens
double stranded ribonuclease viruses such as CMV, TEV
Coat proteins viruses such as CMV, TEV
17kDa or 60 kDa protein viruses such as CMV, TEV
Nuclear inclusion proteins eg. a or b or viruses such as CMV, TEV
Nucleoprotein
Pseudoubiquitin viruses such as CMV, TEV
Replicase viruses such as CMV, TEV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, whitefiies aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins


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Effected target or expressed principie(s) Crop phenotype / Tolerance to

3- Hydroxysteroid oxidase iepidoptera, whiteflies aphids
Peroxidase lepidoptera, whiteflies aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, whiteflies aphids
aminopeptidase inhibitor
Lectines lepidoptera, whiteflies aphids
Protease Inhibitors eg cystatin, patatin lepldoptera, whitefiies aphids
ribosome inactivating protein lepidoptera, whiteflies aphids
stilbene synthase lepidoptera, whitefiies aphids
HMG-CoA reductase lepidoptera, whitefiies aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
Antifeeding principies nematodes eg root knot nematodes and
cyst nematodes

Table A9: Crop Grapes

Effected target or expressed principie(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as lsoxaflutol or
(HPPD) Isoxachiortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transterase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenyiosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
-27-
Effected target or expressed principle(s) Crop phenotype / Toleranoe to

catabolism
Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such
as Bromoxynil and loxinyi
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Giyphosate oxidoreduC.ar.e a!yphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides;
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like
oxidase antisense Botrytis and powdery mildew
Metallothionein bacterial and fungal pathogens like
Botrytis and powdery mildew
Ribonuclease bacterial and fungal pathogens like
Botrytis and powdery mildew
Antifungal polypeptide AIyAFP bacterial and fungal pathogens like
Botrytis and powdery mildew
oxalate oxidase bacterial and fungal pathogens like
Botrytis and powdery mildew
glucose oxidase bacterial and fungal pathogens like
Botrytis and powdery mildew
pyrrolnitrin synthesis genes bacterial and fungal pathogens like
Botrytis and powdery mildew
serine/threonine kinases bacterial and fungal pathogens like
Botrytis and powdery mildew
Cecropin B bacterial and fungal pathogens like
Botrytis and powdery mildew
Phenylalanine ammonia lyase (PAL) bacterial and fungat pathogens like
Botrytis and powdery mildew
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like


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Effected target or expressed principie(s) Crop phenotype / Toierance to

Botrytis and powdery mildew
Osmotin bacteriai and fungal pathogens like
Botrytis and powdery mildew
Alpha Hordothionin bacterial and fungal pathogens like
Botrytis and powdery mildew
Systemin bacterial and fungal pathogens like
Botryas and powdery mildew
Polygalacturonase inhibitors bacterial and fungal pathogens like
Botrytis and powdery mildew
Prf regulatory gene bacterial and fungal pathogens like
Botrytis and powdery mildew
phytoalexins bacterial and fungal pathogens like
Botrytis and powdery mildew
B-1,3-glucanase anbsense bacteriai and fungal pathogens like
Botrytis and powdery mildew

receptor kinase bacteriai and fungal pathogens like
Botrytis and powdery mildew
Hypersensitive response eliciting bacterial and fungal pathogens like
poiypeptide Botrytis and powdery mildew
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens like
Botrytis and powdery mildew
Barnase bacterial and fungal pathogens like
Botrytis and powdery mildew
Glucanases bacterial and fungal pathogens like
Botrytis and powdery mildew
double stranded ribonuclease viruses
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or viruses


CA 02317050 2000-06-27

WO 99/35913 PCT~~~IS3
-29-

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Nucleoprotein
Pseudoubiquidn viruses
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, iepidoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids
Peroxidase lepidoptera, aphids
Aminopeptidase inhibitors eg. Leucine iepidoptera, aphids
aminopeptidase inhibitor
Lectines lepidoptera, aphids
Protease Inhibitors eg cystatin, patatin lepidoptera, aphids
ribosome inactivating protein lepidoptera, aphids
stilbene synthase lepidoptera, aphids, diseases
HMG-CoA reductase lepidoptera, aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes or general diseases
CBI root knot nematodes
Antifeeding principles nematodes eg root knot nematodes or
root cyst nematodes

Table A10: crop Oil Seed rape

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtatides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase lsoxazoles such as isoxaflutol or
(HPPD) Isoxachlortol, Triones such as


CA 02317050 2000-06-27

WO 99/35913 1'CT/EP99M183
-30-
Effected target or expressed principle(s) Crop phenotype / Tolerance to

mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase altered lignin ievels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adehylosuccinQte synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihaio-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyraZoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Suifonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like
oxidase antisense Cylindrosporium, Phoma, Sderotinia
Metallothionein bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sderotinia
Ribonuclease bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Antifungal polypeptide AIyAFP bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
oxalate oxidase bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
glucose oxidase bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
pyrroinitrin synthesis genes bacterial and tungal pathogens like
Cylindrosporium, Phoma, Sclerotinia


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Effected target or expressed principle(s) Crop phenotype / Toleranoa to

serine/threonine kinases bacterial and fungat pathogens like
Cylindrosporium, Phoma, Sclerotinia
Cecropin B bacterial and fungal pathogens like
Cyiindrosporium, Phoma, Scierotinia
Phenyialanine ammonia lyase (PAL) bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Cf genes eg. Cf 9 Cf5 Cf4Cf2 bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Osmotin bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Alpha Hordothionin bacteriai and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Systemin bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
Polygalacturonase inhibttors bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Prf regulatory gene bacterial and fungal pathogens like
Cytindrosporium, Phoma, Scierotinia
phytoalexins bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
B-1,3-glucanase antisense bacterial and fungal pathogens like
Cylindrosporium, Phoma, Scierotinia
receptor kinase bacterial and fungat pathogens like
Cylindrosporium, Phoma, Scierotinia
Hypersensitive response eliciting bacterial and fungal pathogens like
polypeptide Cylindrosporium, Phoma, Sclerotinia
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
Bamase bacterial and fungal pathogens like
Cyiindrosporium, Phoma,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Sclerotinia, nematodes
Glucanases bacterial and fungal pathogens like
Cylindrosporium, Phoma, Sclerotinia
double stranded ribonuclease vinises
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or vinjses
Nucleoprotein
Pseudoubiquitin vinises
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids
Peroxidase lepidoptera, aphids
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids
aminopeptidase inhibitor
Lectines lepidoptera, aphids
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids
CPTI
ribosome inactivating protein lepidoptera, aphids
stilbene synthase lepidoptera, aphids, diseases
HMG-CoA reductase lepidoptera, aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A11: Crop Brassica vegetabie (cabbage, brussel sprouts, broccoli etc.)


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Acetolactate synthase (ALS) . Sutfonylureas, lmidazolinones,
Triazolopyrimidines,
Pyrimidyioxybenzoates, Phtalides
AcetylCoA Carboxyiase (ACCase) Aryioxyphenoxyalkanecarboxyfic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazo!es such as Isoxaflutol or
(HPPD) Isoxachlortoi, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such
as Bromoxynil and loxinyl
5-Enoipyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopyiate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonyiureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens
oxidase antisense
Metallothionein bacterial and fungal pathogens
Ribonuclease bacterial and fungal pathogens
Antifungai polypeptide AIyAFP bacterial and fungal pathogens
oxalate oxidase bacterial and fungal pathogens
glucose oxidase bacteriai and fungal pathogens


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
pyrroinitrin synthesis genes bacterial and fungal pathogens
serine/threonine kinases bacterial and fungal pathogens
Cecropin B bacterial and fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial and fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Ct2 bacterial and fungal pathogens
Osmatir~ bacterial and fungal pathogens
Alpha Hordothionin bacterial and fungal pathogens
Systemin bacterial and fungal pathogens
Polygalacturonase inhibitors bacterial and fungal pathogens
Prt regulatory gene bacterial and fungal pathogens
phytoalexins bacterial and fungal pathogens
B-1,3-glucanase antisense bacterial and fungal pathogens
receptor kinase bacterial and fungal pathogens
Hypersensitive response eliciting bacterial and fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Chitinases bacterial and fungal pathogens
Bamase bacterial and fungal pathogens
Glucanases bacterial and fungal pathogens
double stranded ribonuclease viruses
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or viruses
Nucleoprotein
Pseudoubiquitin viruses
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, iepidoptera, aphids
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids
Peroxidase lepidoptera, aphids


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Effected target or expressed principie(s) Crop phenotype / Tolerance to
Aminopeptidase inhibitors eg. Leucine iepidoptera, aphids
aminopeptidase inhibitor
Lectines iepidoptera, aphids
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids
CPTI
ribosome inact'riating protein lepidoptera, aphids
stilbene synthase lepidoptera, aphids, diseases
HMG-CoA reductase lepidoptera, aphids
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A12: Crop Pome fruits eg apples, pears

Effected target or expressed principle(s) Crop phenotype / Toierance to
Acetolactate synthase (ALS) Sulfonylureas, imidazoiinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtatides
AcetylCoA Carboxylase (ACCase) Aryioxyphenoxyaikanecarboxytic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase isoxazoies such as Isoxaflutol or
(HPPD) isoxachiortoi, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase inhibitors of adenyiosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

cataboNsm
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoredu~'.ase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenyipyraazoies, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial and fungal pathogens like
oxidase antisense apple scab or firebiight
Metallothionein bacterial and fungal pathogens like
apple scab or fireblight
Ribonuclease bacterial and tungal pathogens like
apple scab or fireblight

Antifungal polypeptide AIyAFP bacterial and fungal pathogens like apple scab
or firebiight

oxalate oxidase bacterial and fungal pathogens like
apple scab or fireblight
glucose oxidase bacterial and fungal pathogens like
apple scab or fireblight
pyrroinitrin synthesis genes bacterial and fungal pathogens like
apple scab or fireblight
serine/threonine kinases bacterial and fungal pathogens like
apple scab or fireblight
Cecropin B bacterial and fungal pathogens like
apple scab or fireblight
Phenylaianine ammonia lyase (PAL) bacterial and fungal pathogens like
apple scab or fireblight
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial and fungal pathogens like


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

apple scab or firebUght
Osmotin bacterial and fungal pathogens like
apple scab or firebiight
Alpha Hordothionin bacterial and fungal pathogens like
apple scab or fireblight
Sysiemir~ bacterial and tungal patnogens iiKe
apple scab or firebiight
Polygalacturonase inhibitors bacterial and fungal pathogens like
apple scab or fireblight
Prf regulatory gene bacteriat and fungal pathogens like
apple scab or fireblight
phytoalexins bacterial and fungal pathogens like
apple scab or fireblight
B-1,3-glucanase antisense bacterial and fungal pathogens like
apple scab or fireblight
receptor kinase bacterial and fungal pathogens like
apple scab or fireblight
Hypersensitive response eliciting bacterial and fungal pathogens like
polypeptide apple scab or fireblight

Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial and fungal pathogens Gke
apple scab or fireblight
Lysozym bacterial and fungal pathogens like
apple scab or firebiight
Chitinases bacteriai and fungal pathogens like
apple scab or fireblight
Bamase bacterial and fungal pathogens like
apple scab or fireblight
Glucanases bacterial and fungal pathogens like
apple scab or fireblight


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.38.

Effected target or expressed principle(s) Crop phenotype / Tolerance to
double stranded ribonuclease viruses
Coat proteins viruses
17kDa or 60 kDa protein viruses
Nuclear inclusion proteins eg. a or b or vinms
Nucleoprotein
Pseudoubiquitin viruses
Replicase viruses
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites
Peroxidase lepidoptera, aphids, mites
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites
aminopeptidase inhibitor
Lectines lepidoptera, aphids, mites
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites
CPTI
ribosome inactivating protein lepidoptera, aphids, mites
stilbene synthase lepidoptera, aphids, diseases, mites
HMG-CoA reductase lepidoptera, aphids, mites
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A13: Crop Melons

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonyiureas, Imidazolinones,
Triazolopyrimidines,


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Effected target or expressed principie(s) Crop phenotype / Tolerance to
Pyrimidyioxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyaikanecarboxyiic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase isoxazoies such as isoxafiutol or
(HPPD) isoxachtortoi, Triones such as
mesoftne or suicotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sutfonylureas
Polyphenol oxidase or Polyphenol bacteriai or fungal pathogens like
oxidase antisense phytophtora
Metallothionein bacterial or fungal pathogens like
phytophtora
Ribonuclease bacterial or fungal pathogens like
phytophtora
Antifungal polypeptide AIyAFP bacterial or fungal pathogens like
phytophtora


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Effected target or expressed principie(s) Crop phenotype / Toierance to

oxalate oxidase bacterial or fungal pathogens like
phytophtora
glucose oxidase bacterial or fungal pathogens iike
phytophtora
pyrroinitrin synthesis genes bacteriai or fungal pathogens iike
phytophtora
serine/threonine kinases bacterial or fungal pathogens like
phytophtora
Cecropin B bacterial or fungal pathogens like
phytophtora
Phenyiaianine ammonia lyase (PAL) bacterial or fungal pathogens like
phytophtora
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens like
phytophtora
Osmotin bacterial or fungal pathogens like
phytophtora
Alpha Hordothionin bacterial or fungal pathogens like
phytophtora
Systemin bacterial or fungal pathogens like
phytophtora
Polygalacturonase inhibitors bacterial or fungal pathogens like
phytophtora
Prf regulatory gene bacterial or fungal pathogens like
phytophtora -
phytoalexins bacterial or fungal pathogens like
phytophtora
B-1,3-giucanase antisense bacterial or fungal pathogens like
phytophtora
receptor kinase bacterial or fungal pathogens like
phytophtora
Hypersensitive response eiiciting bacterial or fungal pathogens like
polypeptide phytophtora


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Effected target or expressed principle(s) Crop phenotype / Toierance to
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodai
genes pathogens
Lytic protein bacterial or fungal pathogens like
phytophtora
Lysozym bacterial or fungal pathogens like
phytophtora

Chitinases bacterial or fungal pathogens like
phytophtora
Bamase bacterial or fungal pathogens like
phytophtora
Glucanases bacterial or fungal pathogens like
phytophtora
double stranded ribonuclease viruses as CMV,, PRSV, WMV2, SMV,
ZYMV . l
Coat proteins viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
17kDa or 60 kDa protein viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
Nuciear inclusion proteins eg. a or b or viruses as CMV,, PRSV, WMV2, SMV,
Nucleoprotein ZYMV
Pseudoubiquitin viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
Replicase viruses as CMV,, PRSV, WMV2, SMV,
ZYMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, whitefly
Peroxidase iepidoptera, aphids, mites, whitefiy
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, whitefiy
aminopeptidase inhibitor


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Effected target or expressed principie(s) Crop phenotype / Toierance to

Lectines lepidoptera, aphids, mites, whitefiy
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites, whitefiy
CPTI, virgiferin
ribosome inactivating protein iepidoptera, aphids, mites, whitefiy
stilbene synthase iepidoptera, aphids, mites, whftefly
HMG-CaA reductase fepidoptera, aphids, mites, wnitefly
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A14: Crop Banana

Effected target or expressed principle(s) Crop phenotype / Toierance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryioxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaflutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or suicotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transf erase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-ben2onitriles such


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Effected target or expressed principle(s) Crop phenotype / Toierance to

as Bromoxynii and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or suifosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin denvativps,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens
glucose oxidase bacterial or fungal pathogens
pyrrolnitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylalanine ammonia lyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens
Hypersensitive response eiiciting bacterial or tungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, tungal, nematodai


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens
Chftinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuclease viruses as Banana bunchy top virus
(BBTV)
Coat proteins viruses as Banana bunchy top virus
(BBTV)
17kDa or 60 kDa protein viruses as Banana bunchy top virus
(BBTV)
Nuclear inciusion proteins eg. a or b or viruses as Banana bunchy top virus
Nucleoprotein (BBTV)
Pseudoubiquitin viruses as Banana bunchy top virus
(BBTV)
Replicase viruses as Banana bunchy top virus
(BBTV)
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes
Bacillus cereus toxins, Photorabdus and
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes
Peroxidase lepidoptera, aphids, mites, nematodes
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes
aminopeptidase inhibitor
Lectines lepidoptera, aphids, mites, nematodes
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes
CPTI, virgiferin
ribosome inactivating protein lepidoptera, aphids, mites, nematodes
stilbene synthase lepidoptera, aphids, mites, nematodes
HMG-CoA reductase tepidoptera, aphids, mites, nematodes
Cyst nematode hatching stimulus cyst nematodes


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A 15: Crop Cotton

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, tmidazolinones,
Triazoiopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxaftutol or
(HPPD) Isoxachiortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriles such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungai pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungai pathogens
Antifungal polypeptide AfyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens
glucose oxidase bacterial or fungal pathogens
pyrroinitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylaianine ammonia iyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens
Chitinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or tungal pathogens
double stranded ribonuclease viruses as wound tumor virus (WTV)


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Effected target or expressed principie(s) Crop phenotype / Toierance to

Coat proteins viruses as wound tumor virus (WTV)
17kDa or 60 kDa protein viruses as wound tumor virus (WTV)
Nuclear inclusion proteins eg. a or b or viruses as wound tumor virus (WTV)
Nucleoprotein
Pseudoubiquitin viruses as wound tumor virus (WTV)
Repiicase viruses as wound tumor virus (WTV)
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefly
Xenorhabdus toxins
3- Hydroxysteroid oxidase iepidoptera, aphids, mites, nematodes,
whitefly
Peroxidase iepidoptera, aphids, mites, nematodes,
whitefly
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly
Lectines lepidoptera, aphids, mites, nematodes,
whitefly
Protease Inhibitors eg cystatin, patatin, iepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whitefly
ribosome inactivating protein lepidoptera, aphids, mites, nematodes,
whitefly
stilbene synthase lepidoptera, aphids, mites, nematodes,
whitefly
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes


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Tabte A 16: Crop Sugarcane

Effected target or expressed principte(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Suffonylureas, Imidazolinones,
Triazolopyrimidines,
Pyrimidyioxybenzoates, Phtalides
AcetylCcA Carboxylese (ACCase) Aryioxyphenoxyalkenecarboxytic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase lsoxazotes such as Isoxaftutol or
(HPPD) Isoxachlortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihato-4-hydroxy-benzonitrites such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazotes, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Potyphenol bacterial or fungal pathogens
oxidase antisense
Metallothionein bacterial or tungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens


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Effected target or expressed principle(s) Crop phenotype / Tolerance to

oxalate oxidase bacterial or fungal pathogens
glucose oxidase bacterial or fungal pathogens
pyrroinitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenylatanine ammonia lyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) virai, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens eg
clavibacter
Chitinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuclease viruses as SCMV, SrMV
Coat proteins viruses as SCMV, SrMV
17kDa or 60 kDa protein viruses as SCMV, SrMV
Nuclear inclusion proteins eg. a or b or viruses as SCMV, SrMV
Nucleoprotein
Pseudoubiquitin viruses as SCMV, SrMV
Replicase viruses as SCMV, SrMV


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
Bacillus thuringiensis toxins, VIP 3, iepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefiy, beeties eg mexican rice
borer
Xenorhabdus toxins
3- Hydroxysteroid oxidase iepidoptera, aphids, mites, nematodes,
whitefiy, beetles eg mexican rice borer
Peroxidase iepkloptera, aphids, mites. nematodes,
whitefly, beetles eg mexican rice borer
Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly, beetles eg mexican rice borer
Lectines iepidoptera, aphids, mites, nematodes,
whitefiy, beetles eg mexican rice borer
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whitefly, beetles eg mexican rice borer
ribosome inactivating protein lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
stilbene synthase lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly, beetles eg mexican rice borer
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A 17: Crop Sunflower

Effected target or expressed principle(s) Crop phenotype / Toierance to
Acetolactate synthase (ALS) Sulfonylureas, Imidazolinones,


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Effected target or expressed principie(s) Crop phenotype / Tolerance to
Triazoiopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryioxyphenoxyalkanecarboxylic acids,
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase Isoxazoles such as Isoxafiutol or
(HPPD) Isoxacniortol, Triones such as
mesotrione or suicotrione
Phosphinothricin acetyl transferase Phosphinothricin
0-Methyl transferase altered lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihalo-4-hydroxy-benzonitriies such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or suifosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonyiureas
Polyphenol oxidase or Polyphenol bacterial or tungal pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens eg
scierotinia
glucose oxidase bacterial or fungal pathogens


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Effected target or expressed principle(s) Crop phenotype / Toierance to
pyrroinitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacterial or fungal pathogens
Phenyiafanine ammonia iyase (PAL) bacteriai or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacteriai or fungai pathogens
Osmatin bacterial or tungat pathogens
Alpha Hordothionin bacteriai or fungal pathogens
Systemin bacteriai or fungal pathogens
Polygalacturonase inhibitors bacterial or fungal pathogens
Prf regulatory gene bacteriai or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-giucanase antisense bacterial or fungal pathogens
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacteriai, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungal pathogens
Lysozym bacterial or fungal pathogens
Chitinases bacterial or fungal pathogens
Bamase bacteriai or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuciease viruses as CMV, TMV
Coat proteins viruses as CMV, TMV
17kDa or 60 kDa protein viruses as CMV, TMV
Nuclear inclusion proteins eg. a or b or viruses as CMV, TMV
Nucleoprotein
Pseudoubiquitin viruses as CMV, TMV
Replicase viruses as CMV, TMV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefiy, beeties
Xenorhabdus toxins


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Effected target or expressed principle(s) Crop phenotype / Toierance to

3- Hydroxysteroid oxidase iepidoptera, aphids, mites, nematodes,
whitefly, beetles
Peroxidase iepidoptera, aphids, mites, nematodes,
whitefly, beetles

Aminopeptidase inhibitors eg. Leucine lepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly, beeties
Lectines lepidoptera, aphids, mites, nematodes,
whitefly, beetles
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whitefly, beetles
ribosome inactivating protein iepidoptera, aphids, mites, nematodes,
whitefly, beetles
stilbene synthase iepidoptera, aphids, mites, nematodes,
whitefly, beetles
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly, beetles
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

Table A 18: Crop Sugarbeet, Beet root

Effected target or expressed principle(s) Crop phenotype / Tolerance to
Acetolactate synthase (ALS) Sulfonylureas, lmidazolinones,
Triazolopyrimidines,
Pyrimidyloxybenzoates, Phtalides
AcetylCoA Carboxylase (ACCase) Aryloxyphenoxyalkanecarboxylic acids,


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Effected target or expressed principie(s) Crop phenotype / Toierance to
cyclohexanediones
Hydroxyphenylpyruvate dioxygenase lsoxazoles such as isoxaflutol or
(HPPD) isoxachtortol, Triones such as
mesotrione or sulcotrione
Phosphinothricin acetyl transferase Phosphinothricin
O-Methyl transferase alterrd lignin levels
Glutamine synthetase Glufosinate, Bialaphos
Adenylosuccinate Lyase (ADSL) Inhibitors of IMP and AMP synthesis
Adenylosuccinate Synthase Inhibitors of adenylosuccinate synthesis
Anthranilate Synthase Inhibitors of tryptophan synthesis and
catabolism
Nitrilase 3,5-dihaio-4-hydroxy-benzonitriies such
as Bromoxynil and loxinyl
5-Enolpyruvyl-3phosphoshikimate Glyphosate or sulfosate
Synthase (EPSPS)
Glyphosate oxidoreductase Glyphosate or sulfosate
Protoporphyrinogen oxidase (PROTOX) Diphenylethers, cyclic imides,
phenylpyrazoles, pyridin derivatives,
phenopylate, oxadiazoles etc.
Cytochrome P450 eg. P450 SU1 or Xenobiotics and herbicides such as
selection Sulfonylureas
Polyphenol oxidase or Polyphenol bacterial or fungal pathogens
oxidase antisense
Metallothionein bacterial or fungal pathogens
Ribonuclease bacterial or fungal pathogens
Antifungal polypeptide AIyAFP bacterial or fungal pathogens
oxalate oxidase bacterial or fungal pathogens eg
scierotinia
glucose oxidase bacterial or fungal pathogens
pyrroinitrin synthesis genes bacterial or fungal pathogens
serine/threonine kinases bacterial or fungal pathogens
Cecropin B bacteriai or fungal pathogens


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Effected target or expressed principle(s) Crop phenotype / Toleranoe to

Phenylalanine ammonia iyase (PAL) bacterial or fungal pathogens
Cf genes eg. Cf 9 Cf5 Cf4 Cf2 bacterial or fungal pathogens
Osmotin bacterial or fungal pathogens
Alpha Hordothionin bacterial or fungal pathogens
Systemin bacterial or fungal pathogens
Polygalacturonase inhibitors bacterial or funga! rathoge.~.s
Prf regulatory gene bacterial or fungal pathogens
phytoalexins bacterial or fungal pathogens
B-1,3-glucanase antisense bacterial or fungal pathogens
AX + W!N proteins bacterial or fungal pathogens like
Cercospora beticola
receptor kinase bacterial or fungal pathogens
Hypersensitive response eliciting bacterial or fungal pathogens
polypeptide
Systemic acquires resistance (SAR) viral, bacterial, fungal, nematodal
genes pathogens
Lytic protein bacterial or fungai pathogens
Lysozym bacterial or fungal pathogens
Chitinases bacterial or fungal pathogens
Bamase bacterial or fungal pathogens
Glucanases bacterial or fungal pathogens
double stranded ribonuclease viruses as BNYVV
Coat proteins viruses as BNYVV
17kDa or 60 kDa protein viruses as BNYVV
Nuclear inclusion proteins eg. a or b or viruses as BNYVV
Nucleoprotein
Pseudoubiquitin viruses as BNYVV
Replicase viruses as BNYVV
Bacillus thuringiensis toxins, VIP 3, lepidoptera, aphids, mites, nematodes,
Bacillus cereus toxins, Photorabdus and whitefly, beetles, rootflies
Xenorhabdus toxins
3- Hydroxysteroid oxidase lepidoptera, aphids, mites, nematodes,


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Effected target or expressed principle(s) Crop phenotype / Tolerance to
whitefiy, beeties, rootflies
Peroxidase lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies
Aminopeptidase inhibttors eg. Leucine iepidoptera, aphids, mites, nematodes,
aminopeptidase inhibitor whitefly, beetles, rootflies
Lectines lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootfiies
Protease Inhibitors eg cystatin, patatin, lepidoptera, aphids, mites,
nematodes,
CPTI, virgiferin whitefly, beetles, rootflies
ribosome inactivating protein lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootflies
stilbene synthase lepidoptera, aphids, mites, nematodes,
whftefly, beetles, rootflies
HMG-CoA reductase lepidoptera, aphids, mites, nematodes,
whitefly, beetles, rootfiies
Cyst nematode hatching stimulus cyst nematodes
Bamase nematodes eg root knot nematodes and
cyst nematodes
Beet cyst nematode resistance locus cyst nematodes
CBI root knot nematodes
Antifeeding principles induced at a nematodes eg root knot nematodes, root
nematode feeding site cyst nematodes

The abovementioned animal pests which can be controlled by the method
according to the
invention include; for example, insects, representatives of the order acarina
and
representatives of the class nematoda; especially

from the order Lepidoptera Acieris spp., Adoxophyes spp., especially
Adoxophyes
reticulana; Aegeria spp., Agrotis spp., especially Agrotis spinifera; Alabama
argillaceae,
Amylois spp., Anticarsia gemmatalis, Archips spp., Argyrotaenia spp.,
Autographa spp.,
Busseola fusca, Cadra cautelia, Carposina nipponensis, Chilo spp.,
Choristoneura spp.,
Clysia ambiguella, Cnaphalocrocis spp., Cnephasia spp., Cochylis spp.,
Coleophora spp.,
Crocidolomia binotalis, Cryptophlebia leucotreta, Cydia spp., especially Cydia
pomonella;


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Diatraea spp., Diparopsis castanea, Earias spp., Ephestfa spp., especially E.
KhiinieUa;
Eucosma spp., Eupoecilia ambiguelia, Euproctis spp., Euxoa spp., Grapholita
spp., Hedya
nubiferana, Heliothis spp., especially H. Virescens und H. zea; Hellula
undalis, Hyphantria
cunea, Keiferia lycopersicella, Leucoptera scitella, Lithocollethis spp.,
Lobesiaspp.,
Lymantria spp., Lyonetia spp., Malacosoma spp., Mamestra brassicae, Manduca
sexta,
Operophtera spp., Ostrinia nubilaiis, Pammene spp., Pandemis spp., Panolis
flammea,
Pectinophora spp.. Phthorimaea operculetla, Pieris rapae, Pleris spp.,
Plutelia xylostella,
Prays spp., Scirpophaga spp., Sesamia spp., Sparganothis spp.,
Spodopteralittoralis,
Synanthedon spp., Thaumetopoea spp., Tortrix spp., Trichoplusia ni and
Yponomeuta spp.;
from the order Coleoptera, for example Agriotes spp., Anthonomus spp.,
Atomaria linearis,
Chaetocnema tibialis, Cosmopolites spp., Curculio spp., Dermestes spp.,
Diabrotica spp.,
Epilachna spp., Eremnus spp., Leptinotarsa decemlineata, Lissorhoptrus spp.,
Melolontha
spp., Oryzaephilus spp., Otiorhynchus spp., Phlyctinus spp., Popillia spp.,
Psylliodes spp.,
Rhizopertha spp., Scarabeidae, Sitophilus spp., Sitotroga spp., Tenebrio spp.,
Tribolium
spp. and Trogoderma spp.;

from the order Orthoptera, for example Blatta spp., Blattella spp.,
Gryllotalpa spp.,
Leucophaea maderae, Locusta spp., Periplaneta spp. and Schistocerca spp.;
from the order isoptera, for example Reticulitermes spp.;

from the order Psocoptera, for example Liposcelis spp.;

from the order Anoplura, for example Haematopinus spp., Linognathus spp.,
Pediculus
spp., Pemphigus spp. and Phylloxera spp.;

from the order Mallophaga, for example Damalinea spp. and Trichodectes spp.;
from the order Thysanoptera, for example Frankliniella spp., Hercinothrips
spp.,
Taeniothrips spp., Thrips paimi, Thrips tabaci and Scirtothrips aurantii;

from the order Heteroptera, for example Cimex spp., Distantiella theobroma,
Dysdercus
spp., Euchistus spp. Eurygaster spp. Leptocorisa spp., Nezara spp., Piesma
spp., Rhodnius
spp., Sahlbergella singularis, Scotinophara spp. and Triatoma spp.;

from the order Homoptera, for example Aleurothrixus floccosus, Aleyrodes
brassicae,
Aonidiella aurantii, Aphididae, Aphis craccivora, A. fabae, A. gosypii;
Aspidiotus spp.,
Bemisia tabaci, Ceroplaster spp., Chrysomphalus aonidium, Chrysomphalus
dictyospermi,
Coccus hesperidum, Empoasca spp., Eriosoma lanigerum, Erythroneura spp.,
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spp., Laodelphax spp., Lecanium comi, Lepidosaphes spp., Macrosiphus spp.,
Myzus spp.,
especially M.persicae; Nephotetax spp., especially N. cincticeps; Nilaparvata
spp.,
especially N. lugens; Paratoria spp., Pemphigus spp., Planococcus spp.,
Pseudaulacaspis
spp., Pseudococcus spp., especially P. Fragiiis, P. citriculus and P.
comstocki; Psylia spp.,
especially P. pyri; Pulvlnaria aethiopica, Duadraspidiotus app., Rhopalosiphum
spp.,
Saissetia spp., Scaphoideus spp., Schizaphis spp., Sitobion spp., Trialeurodes
vaporariorum, Trioza erytreae and Unaspis citri;

from the order Hymenoptera, for example Acromyrmex, Atta spp., Cephus spp.,
Diprion
spp., Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium
pharaonis, Neodiprion spp., Solenopsis spp. and Vespa spp.;

from the order Diptera, for example Aedes spp., Antherigona soccata, Bibio
hortulanus,
Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp.,
Cuterebra spp.,
Dacus spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Glossina
spp.,
Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza
spp.,
Musca spp., Oestrus spp., Orseolia spp., Oscinelia frit, Pegomyia hyoscyami,
Phorbia spp.,
Rhagoletis pomonella, Sciara spp., Stomoxys spp., Tabanus spp., Tannia spp.
and Tipula
spp.;

from the order Siphonaptera, for example Ceratophyllus spp. and Xenopsylla
cheopis;
from the order Thysanura, for example Lepisma saccharina and

from the order Acarina, for example Acarus siro, Aceria sheldoni; Aculus spp.,
especially A.
schlechtendaii; Amblyomma spp., Argas spp., Boophilus spp., Brevipaipus spp.,
especially
B. califomicus and B. phoenicis; Bryobia praetiosa, Calipitrimerus spp:,
Chorioptes app.,
Dermanyssus gallinae, Eotetranychus spp., especially E.carpini and E.
orientalis; Eriophyes
spp., especially E. vitis; Hyalomma spp., Ixodes spp., Olygonychus pratensis,
Omithodoros
spp., Panonychus spp., especially P. ulmi and P. citri; Phyllocoptruta spp.,
especially P.
oleivora; Polyphagotarsonemus spp., especially P. latus; Psoroptes spp.,
Rhipicephalus
spp., Rhizoglyphus spp., Sarcoptes spp., Tarsonemus spp. and Tetranychus spp.,
in
particular T. urticae, T. cinnabarinus and T. Kanzawai;

representatives of the class Nematoda;

(1) nematodes selected from the group consisting of root knot nematodes, cyst-
forming
nematodes, stem eelworms and foliar nematodes;


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(2) nematodes selected from the group consisting of Anguina spp.;
Aphelenchoides spp.;
Ditylenchus spp.; Globodera spp., for example Globodera rostochiensis;
Heterodera spp.,
for example Heterodera avenae, Heterodera glycines, Heterodera schachtii or
Heterodera
trifolii; Longidorus spp.; Meloidogyne spp., for example Meloidogyne incognita
or
Meloidogyne javanica; Pratylenchus, for example Pratylenchus neglectans or
Pratylenchus
penetrans; Radopholus spp., for example Radopholus similis; Trichodorus spp.;
Tylenchulus, for example Tylerichulus semipenetrans; and Xiphinema spp.; or

(3) nematodes selected from the group consisting of Heterodera spp., for
example
Heterodera glycines; and Meloidogyne spp., for example Meloidogyne incognita.

The method according to the invention allows pests of the abovementioned type
to be
controlled, i.e. contained or destroyed, which occur, in pardcular, on
transgenic plants,
mainly useful plants and omamentals in agriculture, in horticulture and in
forests, or on
parts, such as fruits, flowers, foliage, stalks, tubers or roots, of such
plants, the protection
against these pests in some cases even extending to plant parts which form at
a later point
in time.

The method according to the invention can be employed advantageously for
controlling
pests in rice, cereals such as maize or sorghum; in fruit, for example stone
fruit, pome fruit
and soft fruit such as apples, pears, plums, peaches, almonds, cherries or
berries, for
example strawberries, raspberries and blackberries; in legumes such as beans,
lentils, peas
or soya beans; in oil crops such as oilseed rape, mustard, poppies, olives,
sunflowers,
coconuts, castor-oil plants, cacao or peanuts; in the marrow famiiy such as
pumpkins,
cucumbers or melons; in fibre plants such as cotton, flax, hemp or jute; in
citrus fruit such as
oranges, lemons, grapefruit or tangerines; in vegetables such as spinach,
lettuce,
asparagus, cabbage species, carrots, onions, tomatoes, potatoes, beet or
capsicum; in the
laurel family such as avocado, Cinnamonium or camphor; or in tobacco, nuts,
coffee, egg
plants, sugar cane, tea, pepper, grapevines, hops, the banana family, latex
plants or
omamentals, mainly in maize, rice, cereals, soya beans, tomatoes, cotton,
potatoes, sugar
beet, rice and mustard; in particular in cotton, rice, soya beans, potatoes
and maize.

It has emerged that the method according to the invention is valuable
preventatively and/or
curatively in the field of pest control even at low use concentrations of the
pesticidal
composition and that a very favourable biocidal spectrum is achieved thereby.
Combined
with a favourable compatibility of the composition employed with warm-blooded
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fish and plants, the method according to the invention can be employed against
all or
individual developmental stages of normally-sensitive; but also of normally-
resistant, animal
pests such as insects and representatives of the order Acarina, depending on
the species
of the transgenic crop plant to be protected from attack by pests. The
insecticidal and/or
acaricidal effect of the method according to the invention may become apparent
directly, i.e.
in a destruction of the pests which occurs immediately or only after some time
has elapsed,
for example, during ecdysis. or indirectly, for example as a reduced
oviposftion and/or
hatching rate, the good action corresponding to a destruction rate (mortality)
of at least 40
to 50%.

Depending on the intended aims and the prevailing circumstances, the
pesticides within the
scope of invention , which are known per se, are emuisifiable concentrates,
suspension
concentrates, directly sprayable or dilutable solutions, spreadable pastes,
dilute emulsions,
wettable powders, soluble powders, dispersible powders, wettable powders,
dusts, granules
or encapsulations in polymeric substances which comprise a nitroimino- or
nitroguanidino-
compound.

The active ingredients are employed in these compositions together with at
least one of the
auxiliaries conventionally used in art of formulation, such as extenders, for
example
solvents or solid carriers, or such as surface-active compounds (surfactants).

Formulation auxiliaries which are used are, for example, solid carriers,
solvents, stabilizers,
"slow release" auxiliaries, colourants and, if appropriate, surface-active
substances
(surfactants). Suitable carriers and auxiliaries are all those substances
which are con-
ventionally used for crop protection products. Suitable auxiliaries such as
solvents, solid
carriers, surface-active compounds, non-ionic surfactants, cationic
surfactants, anionic
surfactants and other auxiliaries in the compositions employed according to
the invention
are, for example, those which have been described in EP-A-736 252.

These compositions for controlling pests can be formulated, for example, as
wettable
powders, dusts, granules, solutions, emulsifiable concentrates, emulsions,
suspension
concentrates or aerosols. For example, the compositions are of the type
described in EP-
A-736 252.

The action of the compositions within the scope of invention which comprise a
nitroimino- or
nitroguanidino-compound can be extended substantially and adapted to
prevailing
circumstances by adding other insecticidally, acaricidally and/or fungicidally
active


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ingredients. Suitable examples of added active ingredients are representatives
of the
following classes of active ingredients: organophosphorous compounds,
nitrophenois and
derivatives, formamidines, ureas, carbamates, pyrethroids, chlorinated
hydrocarbons;
especially preferred components in mixtures are, for example, abamectin,
emamectin,
spinosad, pymetrozine, fenoxycarb, Ti-435, fipronil, pyriproxyfen, diazinon or
diafenthiuron.
As a rule, the compositions within the scope of Invention comprise 0.1 to 99%,
in particular
0.1 to 95 %, of a nitroimino- or nitroguanidino-compound and 1 to 99.9 %, in
particuiar 5!o
99.9 %, of - at least - one solid or liquid auxiliary, It being possible, as a
rule, for 0 to 25 %,
in particular 0.1 to 20 %, of the compositions to be surfactants (% in each
case meaning per
cent by weight). While concentrated compositions are more preferred as
commercial
products, the end user will, as a rule, use dilute compositions which have
considerably
lower concentrations of active ingredient.

The compositions according to the invention may also comprise other solid or
liquid
auxiliaries, such as stabilisers, for example epoxidized or unepoxidized
vegetable oils (for
example epoxidized coconut oil, rapeseed oil or soya bean oil), antifoams, for
example
silicone oil, preservatives, viscosity regulators, binders and/or tackifiers,
and also fertilizers
or other active ingredients for achieving specific effects, for example,
bactericides,
fungicides, nematicides, molluscicides or herbicides.

The compositions according to the invention are produced in a known manner,
for example
prior to mixing with the auxiliary/auxiliaries by grinding, screening and/or
compressing the
active ingredient, for example to give a particular particie size, and by
intimately mixing
and/or grinding the active ingredient with the auxiliary/auxiliaries. :.

The method according to the. invention for controlling pests of the
abovementioned type is
carried out in a manner known per se to those skilled in the art, depending on
the intended
aims and prevailing circumstances, that is to say by spraying, wetting,
atomizing, dusting,
brushing on, seed dressing, scattering or pouring of the composition. Typical
use concen-
trations are between 0.1 and 1000 ppm, preferably between 0.1 and 500 ppm of
active
ingredient. The application rate may vary within wide ranges and depends on
the soil
constitution, the type of application (foliar application; seed dressing;
application in the seed
furrow), the transgenic crop plant, the pest to be controlled, the climatic
circumstances
prevailing in each case, and other factors determined by the type of
application, timing of
application and target crop. The application rates per hectare are generaily 1
to 2000 g of


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nitroimino- or nitroguanidino-compound per hectare, in particular 10 to 1000
g/ha, preferably
to 500 g/ha, especially preferably 10 to 200 glha.

A preferred type of application in the field of crop protection within the
scope of invention is
application to the foliage of the plants (foliar application), it being
possible to adapt
frequency and rate of application to the risk of infestation with the pest in
question..
However, the active ingredient may also enter into the plants via the root
system (systemic
action), by drenching the site of the plants with a liquid ccmposition or by
incorporating the
active ingredient in solid form into the site of the plants, for example into
the soil, for
example in the form of granules (soil application). In the case of paddy rice
crops, such
granules may be metered into the flooded paddy field.

The compositions according to invention are also suitable for protecting
propagation
material of transgenic plants, for example seed, such as fruits, tubers or
kemels, or plant
cuttings, from animal pests, in particular insects and representatives of the
order Acarina.
The propagation material can be treated with the composition prior to
application, for
example, seed being dressed prior to sowing. The active ingredient may also be
applied to
seed kemels (coating), either by soaking the kemels in a liquid composition or
by coating
them with a solid composition. The composition may also be applied to the site
of
application when applying the propagation material, for example into the seed
furrow during
sowing. These treatment methods for plant propagation material and the plant
propagation
material treated thus are a further subject of the invention.

Examples of formulations of nitroimino- or nitroguanidino-compounds which can
be used in
the method according to the invention , for instance solutions, granules,
dusts, sprayable
powders, emulsion concentrates, coated granules and suspension concentrates,
are of the
type as has been described in, for example, EP-A-580 553, Exampies Fl to F10.

Biological examples
Table B

The following abreviations are used in the table:
Active Principle of transgenic plant: AP
Photorhabdus luminescens: PL
Xenorhabdus nematophilus: XN
Proteinase Inhibitors: Pinh.


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Plant lectins PLec.
Agglutinins: Aggi.
3-Hydroxysteroid oxidase: HO
Cholesteroloxidase: CO
Chitinase: CH
Glucanase: GL
Stilbensynthase SS
Table B.

AP I Control of AP Control of

B. I CryIA(a) Adoxophyes spp. B.18 CrylA(a) Ostrinia nubilalis
B.2 CrylA(a) Agrotis spp. B.19 CryIA(a) Pandemis spp.
B.3 CrylA(a) Alabama B.20 CrylA(a) Pectinophora
argillaceae gossyp.
B.4 CrylA(a) Anticarsia B.21 CryIA(a) Phyllocnistis citrelia
gemmatalis B.22 CrylA(a) Pieris spp.
B.5 CryIA(a) Chilo spp. B.23 CryIA(a) Plutella xylostella
B.6 CryIA(a) Clysia ambiguelia B.24 CryIA(a) Scirpophaga spp.
B.7 CrylA(a) Crocidolomia B.25 CrylA(a) Sesamia spp.
binotalis B.26 CryIA(a) Sparganothis spp.
B.8 CrylA(a) Cydia spp. B.27 CryIA(a) Spodoptera spp.
B.9 CrylA(a) Diparopsis B.28 CrylA(a) Tortrix spp.
castanea B.29 CrylA(a) Trichoplusia ni
B.10 CrylA(a) Earias spp. B.30 CryIA(a) Agriotes spp.
B.11 CrylA(a) Ephestia spp. B.31 CrylA(a) Anthonomus
B. 12 CryIA(a) Heliothis spp. grandis
B.13 CrylA(a) Hellula undalis B.32 CrylA(a) Curculio spp.
B. 14 CryIA(a) Keiferia B.33 CryIA(a) Diabrotica balteata
lycopersicella B.34 CrylA(a) Leptinotarsa spp.
B. 15 CryIA(a) Leucoptera scitella B.35 CrylA(a) Lissorhoptrus spp.
B. 16 CrylA(a) Lithocollethis spp. B.36 CrylA(a) Otiorhynchus spp.
B.17 CrylA(a) Lobesia botrana B.37 CrylA(a) Aleurothrixus spp.


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AP Control of AP Control of
B.38 CryIA(a) Aleyrodes spp. argillaceae
B.39 CrylA(a) Aonidiella spp. B.69 CryiA(b) Anticarsia
B.40 CrylA(a) Aphididae spp. gemmatalis
B.41 CrylA(a) Aphis spp. B.70 CrytA(b) Chilo spp.
B.42 CryIA(a) Bemisia tabaci B.71 CrylA(b) Clysia ambiguella
B.43 CryfA(s) Empoasca spp. B.72 CrylA(b) Crocidolomia
B.44 CrylA(a) Mycus spp. binotalis
B.45 CrylA(a) Nephotettix spp. B.73 CrylA(b) Cydia spp.
B.46 CrylA(a) Nitaparvata spp. B.74 CrylA(b) Diparopsis
B.47 CrylA(a) Pseudococcus spp. castanea
B.48 CryIA(a) Psytia spp. B.75 CrylA(b) Earias spp.
B.49 CryIA(a) Ouadraspidiotus B.76 CrylA(b) Ephestia spp.
spp. B.77 CryIA(b) Heliothis spp.
B.50 CrylA(a) Schizaphis spp. 1.78 CrylA(b) Hellula undalis
B.51 CryIA(a) Trialeurodes spp. B.79 CrylA(b) Keiferia
B.52 CrylA(a) Lyriomyza spp. lycopersicelia
B.53 CrylA(a) Oscinelia spp. B.80 CrylA(b) Leucoptera scitella
B.54 CrylA(a) Phorbia spp. B.81 CrylA(b) Lithocollethis spp.
B.55 CrylA(a) Frankliniella spp. B.82 CrylA(b) Lobesia botrana
B.56 CrylA(a) Thrips spp. B.83 CrylA(b) Ostrinia nubilalis
B.57 CrylA(a) Scirtothrips aurantii B.84 CrylA(b) Pandemis spp.
B.58 CryIA(a) Aceria spp. B.85 CrylA(b) Pectinophora
B.59 CrylA(a) Aculus spp. gossyp.
B.60 CryIA(a) Brevipalpus spp. B.86 CrylA(b) Phyllocnistis citrella
B.61 CrylA(a) Panonychus spp. B.87 CrylA(b) Pieris spp.
B.62 CryIA(a) Phyllocoptruta spp. B.88 CrylA(b) Plutelia xytostelia
B.63 CrylA(a) Tetranychus spp. B.89 CrylA(b) Scirpophaga spp.
B.64 CrylA(a) Heterodera spp. B.90 CrylA(b) Sesamia spp.
B.65 CrylA(a) Meloidogyne spp. B.91 CrylA(b) Sparganothis spp.
B.66 CryIA(b) Adoxophyes spp. B.92 CrylA(b) Spodoptera spp.
B.67 CrylA(b) Agrotis spp. B.93 CrylA(b) Tortrix spp.
B.68 CrylA(b) Alabama B.94 CrylA(b) Trichoplusia ni


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AP Control of AP Control of

B.95 CryIA(b) Agriotes spp. B.125 CryIA(b) Brevipalpus app.
B.96 CrylA(b) Anthonomus B.126 CrylA(b) Panonychus spp.
grandis B.127 CryIA(b) Phyllocoptruta spp.
B.97 CrylA(b) Curculio spp. B.128 CrylA(b) Tetranychus spp.
B.98 CrylA(b) Diabrotica balteata B.129 CrylA(b) Heterodera spp.
B.yy CrylA(b) Leptinolar.a spp. B.130 CryIA(b) Meloidogyne spF.
B.100 CrylA(b) Lissorhoptrus spp. B.131 CrylA(c) Adoxophyes spp.
B.101 CrylA(b) Otiorhynchus spp. B.132 CryIA(c) Agrotis spp.
B.102 CrylA(b) Aleurothrixus spp. B.133 CrylA(c) Alabama
B.103 CryIA(b) Aleyrodes spp. argillaceae
B. 104 CrylA(b) Aonidiella spp. B.134 CrylA(c) Anticarsia
B. 105 CryIA(b) Aphididae spp. gemmatalis
B.106 CryIA(b) Aphis spp. B.135 CryiA(c) Chilo spp.
B.107 CrylA(b) Bemisia tabaci B.136 CryIA(c) Clysia ambiguelia
B.108 CrylA(b) Empoasca spp. B.137 CrylA(c) Crocidotomia
B. 109 CrylA(b) Mycus spp. binotalis
B.110 CrylA(b) Nephotettix spp. B.138 CryIA(c) Cydia spp.
B.l I 1 CrylA(b) Nilaparvata spp. B.139 CrylA(c) Diparopsis
B.112 CrylA(b) Pseudococcus spp. castanea
B.113 CrylA(b) Psylla spp. B.140 CrylA(c) Earias spp.
B.1 14 CrylA(b) Ouadraspidiotus B.141 CryIA(c) Ephestia spp.
spp, B.142 CrylA(c) Hetiothis spp.
B.115 CrylA(b) Schizaphis spp. B.143 CrylA(c) Helluia undalis
B.116 CrylA(b) Trialeurodes spp. B.144 CrylA(c) Keiferia
B.117 CrylA(b) Lyriomyza spp. lycopersicella
B.1 18 CrylA(b) Oscinella spp. B.145 CryIA(c) Leucoptera scitelia
B.119 CrylA(b) Phorbia spp. B.146 CryIA(c) Lithocollethis spp.
B.120 CrylA(b) Frankliniella spp. B.147 CryIA(c) Lobesia botrana
B.121 CrytA(b) Thrips spp. B.148 CryIA(c) Ostrinia nubilalis
B.122 CrylA(b) Scirtothrips aurantii B.149 CrylA(c) Pandemis spp.
B.123 CrylA(b) Aceria spp. B.150 CryIA(c) Pectinophora
B.124 CrylA(b) Aculus spp. gossypiella.


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AP Control of AP Control of

B.151 CrylA(c) Phyllocnistts citrella B.181 CryIA(c) Trialeurodes spp.
B.152 Cry1A(c) Pieris spp. B.182 CryIA(c) Lyriomyza spp.
B.153 Cry1A(c) Plutelia xyiostella B.183 CryIA(c) Oscinelia spp.
B.154 CryIA(c) Scirpophaga spp. B.184 CryIA(c) Phorbia app.
B.155 CryIA(c) Sesamia spp. B.185 CryIA(c) Frankiiniella spp.
B.156 CryIA(c) BFaraarathis spp. B.186 CryIA(c) Thiips spp.
B.157 CryIA(c) Spodoptera spp. B.187 CryIA(c) Scirtothrips aurantii
B.158 CrylA(c) Tortrix spp. B.188 CryIA(c) Aceria spp.
B.159 CrylA(c) Trichopiusia ni B.189 CryIA(c) Aculus spp.
B.160 CrylA(c) Agriotes spp. B.190 CryIA(c) Brevipalpus spp.
B.161 CryIA(c) Anthonomus B.191 CryIA(c) Panonychus spp.
grandis B.192 CrylA(c) Phyllocoptruta spp.
B.162 CrylA(c) Curculio spp. B.193 CryIA(c) Tetranychus app.
B.163 CrylA(c) Diabrotica balteata B.194 CrylA(c) Heterodera spp.
B.164 CryIA(c) Leptinotarsa spp. B.195 CryIA(c) Meloidogyne spp.
B.165 CryIA(c) Lissorhoptrus spp. B.196 CryIIA Adoxophyes spp.
B.166 CryIA(c) Otiorhynchus spp. B.197 CryIlA Agrotis spp.
B.167 CryIA(c) Aieurothrixus spp. B.198 CryliA Alabama
B.168 CryIA(c) Aleyrodes spp. argiliaceae
B.169 CryIA(c) Aonidiella spp. B.199 CryliA Anticarsia
B.170 CryIA(c) Aphididae spp. gemmatalis
B.171 CryIA(c) Aphis spp. B.200 Cry11A Chilo spp.
B.172 CryIA(c) Bemisia tabaci B.201 CryliA Clysia ambiguella
B.173 CryIA(c) Empoasca spp. B.202 CryliA Crocidolomia
B.174 Cry1A(c) Mycus spp. binotalis
B.175 CryIA(c) Nephotettix spp. B.203 CryIlA Cydia spp.
B.176 CryIA(c) Nilaparvata spp. B.204 CryliA Diparopsis
B.177 CryIA(c) Pseudococcus spp. castanea
B.178 CryIA(c) Psylla spp. B.205 CryliA Earias spp.
B.179 CrylA(c) Quadraspidiotus B.206 CryliA Ephestia spp.
spp. B.207 CryliA Heliothis spp.
B.180 CryIA(c) Schizaphis spp. B.208 CryliA Heliula undalis


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AP Control of AP Control of

B.209 CryilA Keiferia B.238 CryllA Empoasca spp.
lycopersicelia B.239 Cry11A Mycus spp.
B.210 CryliA Leucoptera scitella B.240 CryllA Nephotettix spp.
B.211 CryilA Uthocollethis spp. B.241 CryIIA Nilaparvata spp.
B.212 CryliA Lobesia botrana B.242 CryliA Pseudococcus spp.
a'13 CryIlA Ostrinia nublialis B.243 CryilA Psyila spp.
B.214 CryliA Pandemis spp. B.244 CryllA Quadraspidiotus
B.215 CryliA Pectinophora sPP=
gossyp. B.245 CryllA Schizaphis spp.
B.216 CryliA Phyllocnistis citrella B.246 CryliA Trialeurodes spp.
B.217 CryliA Pieris spp. B.247 CryliA Lyriomyza spp.
B.218 CryliA Plutelia xylostelia B.248 CryllA Oscinella spp.
B.219 CryliA Scirpophaga spp. B.249 CryIIA Phorbia spp.
B.220 CryllA Sesamia spp. B.250 CryliA Frankliniella spp.
B.221 CryllA Sparganothis spp. B.251 CryliA Thrips spp.
B.222 CryliA Spodoptera spp. B.252 CryliA Scirtothrips aurantii
B.223 CryllA Tortrix spp. B.253 CryliA Aceria spp.
B.224 CryllA Trichoplusia ni B.254 CryliA Aculus spp.
B.225 CryliA Agriotes spp. B.255 CryilA Brevipaipus spp.
B.226 CryllA Anthonomus B.256 CryliA Panonychus spp.
grandis B.257 CryllA Phyllocoptruta spp.
B.227 CryllA Curcufio spp. B.258 CryliA Tetranychus spp.
B.228 CryliA Diabrotica balteata B.259 CryllA Heterodera spp.
B.229 CryliA Leptinotarsa spp. B.260 CryliA Meloidogyne spp.
B.230 CryllA Lissorhoptrus spp. B.261 CryIlIA Adoxophyes app.
B.231 CryliA Otiorhynchus spp. B.262 CryIIIA Agrotis spp.
B.232 CryllA Aleurothrixus spp. B.263 CryIIIA Alabama
B.233 CryliA Aleyrodes spp. argillaceae
B.234 CryliA Aonidiella spp. B.264 CryIIlA Anticarsia
B.235 CryliA Aphididae spp. gemmatalis
B.236 CryliA Aphis spp. B.265 CrylilA Chilo spp.
B.237 CryliA Bemisia tabaci B.266 CryIIIA Clysia ambiguella


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AP Control of AP Control of

B.267 Cryi11A Crocidolomia B.294 CryIIIA Leptinotansa spp.
binotalis B.295 Cry111A Lissorhoptrus spp.
B.268 Cry111A Cydia spp. B.296 CryIIIA Otiorhynchus spp.
B.269 CrylilA Diparopsis B.297 CryllIA Aleurothrixus spp.
castanea B.298 CryllIA Aleyrodes spp.
B.270 CryIIIA Earias spp. B.299 CrylliA Aonidiefia spp.
B.271 CrylliA Ephestia spp. B.300 Cry111A Aphididae spp.
B.272 CryllIA Heliothis spp. B.301 CrylliA Aphis spp.
B.273 CryllIA Hellula undalis B.302 CryI11A Bemisia tabaci
B.274 CryllIA Keiferia B.303 Cry111A Empoasca spp.
lycopersicella B.304 CryllIA Mycus spp.
B.275 CryllIA Leucoptera scitella B.305 CryIIIA Nephotettix spp.
B.276 CryIIIA Lithocollethis spp. B.306 CrylilA Nilaparvata spp.
B.277 CryllIA Lobesia botrana B.307 CrylliA Pseudococcus spp.
B.278 CrylliA Ostrinia nubilalis B.308 CryllIA Psylla spp.
B.279 CryllIA Pandemis spp. B.309 CryllIA Quadraspidiotus
B.280 CrylliA Pectinophora spp.
gossyp. B.310 CryllIA Schizaphis spp.
B.281 CryllIA Phyllocnistis citrella B.311 CryllIA Trialeurodes spp.
B.282 CryI11A Pieris spp. B.312 Cry111A Lyriomyza spp.
B.283 CryllIA Plutelia xylostelia B.313 CryillA Oscinella spp.
B.284 Cryl11A Scirpophaga spp. B.314 Cry111A Phorbia spp.
B.285 CryllIA Sesamia spp. B.315 CryllIA Frankliniella spp.
B.286 CryllIA Sparganothis spp. B.316 CrylliA Thrips spp.
B.287 CryllIA Spodoptera spp. B.317 CryIIIA Scirtothrips aurantii
R.288 CryIIIA Tortrix spp. B.318 Cry111A Aceria spp.
B.289 CrylliA Trichoplusia ni B.319 CryllIA Aculus spp.
B.290 CryllIA Agriotes spp. B.320 CrylliA Brevipalpus spp.
B.291 CryIIIA Anthonomus B.321 CrylllA Panonychus spp.
grandis B.322 Cry111A Phyllocoptruta spp.
B.292 CryllIA Curculio spp. ' B.323 CryIIIA Tetranychus spp.
B.293 CryllIA Diabrotica balteata B.324 CrylliA Heterodera spp.


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AP Control of AP Control of

B.325 CryIIIA Meloidogyne spp. B.351 CrylllB2 Sparganothis spp.
B.326 CrylllB2 Adoxophyes spp. B.352 CrylllB2 Spodoptera spp.
B.327 CrylllB2 Agrotis spp. B.353 CrylllB2 Tortrix app.
B.328 CrylllB2 Alabama B.354 CrylIIB2 Trichoplusia ni
argiliaceae B.355 CrylllB2 Agriotes spp.
b.;2y CrylllB2 Anticarsia B.356 f.,ry!tlB2 Anthonomus
gemmatalis grandis
B.330 CrylllB2 Chilo spp. B.357 CryI11B2 Curculio spp.
B.331 CrylllB2 Clysia ambiguella B.358 CrylllB2 Diabrotica balteata
B.332 CryIilB2 Crocidolomia B.359 CrylIlB2 Leptinotarsa spp.
binotalis B.360 CryIiIB2 Lissorhoptrus spp.
B.333 CrylllB2 Cydia spp. B.361 CrylllB2 Otiorhynchus spp.
B.334 CrylllB2 Diparopsis B.362 CrylllB2 Aieurothrixus spp.
castanea B.363 CrylllB2 Aleyrodes spp.
B.335 CrylllB2 Earias spp. B.364 CrylllB2 Aonidielia spp.
B.336 CryIlIB2 Ephestia spp. B.365 CrylllB2 Aphididae spp.
B.337 CryIlIB2 Heliothis spp. B.366 CryI11B2 Aphis spp.
B.338 CrylllB2 Helluia undalis B.367 CrylI1B2 Bemisia tabaci
B.339 CrylllB2 Keiferia B.368 CrylllB2 Empoasca spp.
iycopersicelia B.369 CrylllB2 Mycus spp.
B.340 CrylllB2 Leucoptera scitelia B.370 CrylllB2 Nephotettix spp.
B.341 CryllIB2 Lithocollethis spp. B.371 CrylllB2 Nilaparvata spp.
B.342 CrylIIB22 Lobesia botrana B.372 CryIIIB2 Pseudococcus spp.
B.343 CryII1B2 Ostrinia nubilalis B.373 CrylI1B2 Psylla spp.
B.344 CrylllB2 Pandemis spp. B.374 CrylllB2 Quadraspidiotus
B.345 CrylllB2 Pectinophora spp.
gossyp. B.375 CrylI1B2 Schizaphis spp.
B.346 CrylllB2 Phyliocnistis citrella B.376 CrylllB2 Trialeurodes spp.
B.347 CrylllB2 Pieris spp. B.377 CryilIB2 Lyriomyza spp.
B.348 CrylllB2 Plutelia xytostella B.378 CrylllB2 Oscinelia spp.
B.349 CrylllB2 Scirpophaga spp. B.379 CrylliB2 Phorbia spp.
B.350 CrylllB2 Sesamia spp. B.380 CrylllB2 Franklinielia spp.


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AP Control of AP Control of

B.381 CryllIB2 Thrips spp. B.408 CytA Ostrinia nubilalis
B.382 CryII1B2 Scirtothrips aurantii B.409 CytA Pandemis spp.
B.383 CrylllB2 Aceria spp. B.410 CytA Pecbnophora
B.384 CryllIB2 Aculus spp. gossyp=
B.385 CryllIB2 Brevipalpus spp. B.411 CytA Phyllocnistis citrelia
n.3o6 Cry=111B2 Panonychus spp. B.412 CyA Pieris app.
B.387 CryllIB2 Phyllocoptruta spp. B.413 CytA Plutella xyiostella
B.388 CrylllB2 Tetranychus spp. B.414 CytA Scirpophaga spp.
B.389 CryllIB2 Heterodera spp. B.415 CytA Sesamia spp.
B.390 CryllIB2 Meloidogyne spp. B.416 CytA Sparganothis spp.
B.391 CytA Adoxophyes spp. B.417 CytA Spodoptera spp.
B.392 CytA Agrotis spp. B.418 CytA Tortrix spp.
B.393 CytA Alabama B.419 CytA Trichoplusia ni
argillaceae B.420 CytA Agriotes spp.
B.394 CytA Anticarsia B.421 CytA Anthonomus
gemmatalis grandis
B.395 CytA Chilo spp. B.422 CytA Curculio spp.
B.396 CytA Clysia ambiguella B.423 CytA Diabrotica balteata
B.397 CytA Crocidolomia B.424 CytA Leptinotarsa spp.
binotalis B.425 CytA Lissorhoptrus spp.
B.398 CytA Cydia spp. B.426 CytA Otiorhynchus spp.
B.399 CytA Diparopsis B.427 CytA Aleurothrixus spp.
castanea B.428 CytA Aleyrodes spp.
B.400 CytA Earias spp. B.429 CytA Aonidielia spp.
B.401 CytA Ephestia spp. B.430 CytA Aphididae spp.
B.402 CytA Heliothis spp. B.431 CytA Aphis spp.
B.403 CytA Hellula undalis B.432 CytA Bemisia tabaci
B.404 CytA Keiferia B.433 CytA Empoasca spp.
lycopersicella B.434 CytA Mycus spp.
B.405 CytA Leucoptera scitella B.435 CytA Nephotetltx spp.
B.406 CytA Lithocollethis spp. B.436 CytA Nilaparvata spp.
B.407 CytA Lobesia botrana B.437 CytA Pseudococcus spp.


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AP Control of AP Control of
B.438 CytA Psylla spp. B.465 VIP3 Earias spp.
B.439 CYtA Quadraspidiotus B.466 VIP3 Ephestia spp.
$pp. B.467 VIP3 Heliothis spp.
B.440 CytA Schizaphis spp. B.468 VIP3 Hellula undalis
B.441 CytA Trialeurodes spp. B.469 VIP3 Keiferia
B.442 CytA Lyriomyza spp. -ycopers:celle
B.443 CytA Oscinella spp. B.470 VIP3, Leucoptera scitella
B.444 CytA Phorbia spp. B.471 VIP3 Lithocollethis app.
B.445 CytA Franktiniella spp. B.472 VIP3 Lobesia botrana
B.446 CytA Thrips spp. B.473 VIP3 Ostrinia nubiiafis
B.447 CytA Scirtothrips aurantii B.474 VIP3 Pandemis spp.
B.448 CytA Aceria spp. B.475 VIP3 Pectinophora
B.449 CytA Aculus spp. gossyp.
B.450 CytA Brevipalpus spp. B.476 VIP3 Phyllocnistis citrella
B.451 CytA Panonychus spp. B.477 VIP3 Pieris spp.
B.452 CytA Phyllocoptruta spp. B.478 VIP3 Plutelia xylostella
B.453 CytA Tetranychus app. B.479 VIP3 Scirpophaga spp.
B.454 CytA Heterodera spp. B.480 VIP3 Sesamia app.
B.455 CytA Meloidogyne spp. B.481 VIP3 Sparganothis spp.
B.456 VIP3 Adoxophyes spp. B.482 VIP3 Spodoptera spp.
B.457 VIP3 Agrotis spp. B.483 VIP3 Tortrix spp.
B.458 VIP3 Alabama B.484 VIP3 Trichoplusia ni
argillaceae B.485 VIP3 Agriotes spp.
B.459 VIP3 Anticarsia B.486 VIP3 Anthonomus
gemmataiis grandis
B.460 VIP3 Chilo spp. B.487 VIP3 Curculio spp.
B.461 VIP3 Clysia ambiguella B.488 VIP3 Diabrotica batteata
B.462 VIP3 Crocidolomia B.489 VIP3 Leptinotarsa spp.
binotalis B.490 VIP3 Lissorhoptrus spp.
B.463 VIP3 Cydia spp. B.491 VIP3 Otiorhynchus spp.
B.464 VIP3 Diparopsis B.492 VIP3 Aleurothrixus spp.
castanea B.493 VIP3 Aleyrodes epp.


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
=72i
AP Control of AP Control of

B.494 VIP3 Aonidielia spp. B.524 GL Anticarsia
B.495 VIP3 Aphididae spp. gemmatalis
B.496 VIP3 Aphis spp. B.525 GL Chilo spp.
B.497 VIP3 Bemisia tabaci B.526 GL Clysia ambiguella
B.498 VIP3 Empoasca app. B.527 GL Crocidolomia
B.499 VIP3 Mycus spp. binotatis
B.500 VIP3 Nephotettix spp. B.528 GL Cydia spp.
B.501 VIP3 Nilaparvata spp. B.529 GL Diparopsis
B.502 VIP3 Pseudococcus spp. castanea
B.503 VIP3 Psylla spp. B.530 GL Earias spp.
B.504 VIP3 Ouadraspidiotus B.531 GL Ephestia spp.
spp. B.532 GL Heliothis spp.
B.505 VIP3 Schizaphis spp. B.533 GL Hellula undalis
B.506 VIP3 Trialeurodes spp. B.534 GL Keiferia
B.507 VIP3 Lyriomyza spp. lycopersicelia
B.508 VIP3 Oscinella spp. B.535 GL Leucoptera scitelia
B.509 VIP3 Phorbia spp. B.536 GL Lithocollethis app.
B.510 VIP3 Franklinieila spp. B.537 GL Lobesia botrana
B.511 VIP3 Thrips spp. B.538 GL Ostrinia nubilalis
B.512 VIP3 Scirtothrips aurantii B.539 GL Pandemis spp.
B.513 VIP3 Aceria spp. B.540 GL Pectinophora
B.514 VIP3 Aculus spp. gossyp.
B.515 VIP3 Brevipaipus spp. B.541 GL Phyllocnistis citrelia
B.516 VIP3 Panonychus spp. B.542 GL Pieris spp.
B.517 VIP3 Phyllocoptruta spp. B.543 GL Plutelia xylostella
B.518 VIP3 Tetr=anychus spp. B.544 GL Scirpophaga spp.
B.519 VIP3 Heterodera spp. B.545 GL Sesamia spp.
B.520 VIP3 Meloidogyne spp. B.546 GL Sparganothis spp.
B.521 GL Adoxophyes spp. B.547 GL Spodoptera spp.
B.522 GL Agrotis spp. B.548 GL Tortrix spp.
B.523 GL Alabama B.549 GL Trichoplusia ni
argillaceae B.550 GL Agriotes spp.


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
-73-
AP Control of AP Control of

B.551 GL Anthonomus B.581 GL Panonychus spp.
grandis B.582 GL Phyllocoptruta spp.
B.552 GL Curculio spp. B.583 GL Tetranychus spp.
B.553 GL Diabrotica balteata B.584 GL Heterodera spp.
B.554 GL Leptinotarsa spp. B.585 GL Meloidogyne spp.
;.555 GL Lissorhoptrus spp. B.586 PL Acbxophyes spp.
B.556 GL Otiorhynchus spp. B.587 PL Agrotis spp.
B.557 GL Aleurothrixus spp. B.588 PL Alabama
B.558 GL Aleyrodes spp. argillaceae
B.559 GL Aonidiella spp. B.589 PL Anticarsia
B.560 GL Aphididae spp. gemmatalis
B.561 GL Aphis spp. B.590 PL Chilo spp.
B.562 GL Bemisia tabaci B.591 PL Clysia ambiguelia
B.563 GL Empoasca spp. B.592 PL Crocidolomia
B.564 GL Mycus spp. binotalis
B.565 GL Nephotettix spp. B.593 PL Cydia spp.
B.566 GL Nilaparvata spp. B.594 PL Diparopsis
B.567 GL Pseudococcus spp. castanea
B.568 GL Psylla spp. B.595 PL Earias spp.
B.569 GL Quadraspidiotus B.596 PL Ephestia spp.
spp. B.597 PL Heliothis spp.
B.570 GL Schizaphis spp. B.598 PL Hellula undalis
B.571 GL Trialeurodes spp. B.599 PL Keiferia
B.572 GL Lyriomyza spp. lycopersicella
B.573 GL Oscinelia spp. B.600 PL Leucoptera scitella
B.574 GL Phorbia spp. B.601 PL Lithocollethis spp.
B.575 GL Frankliniella spp. B.602 PL Lobesia botrana
B.576 GL Thrips spp. B.603 PL Ostrinia nubilalis
B.577 GL Scirtothrips aurantii B.604 PL Pandemis spp.
B.578 GL Aceria spp. B.605 PL Pectinophora
B.579 GL Aculus spp. gossyp.
B.580 GL Brevipalpus spp. B.606 PL Phyllocnistis citrella


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
-74-
AP Control of AP Control of

B.607 PL Pieris app. B.637 PL Lyriomyza spp.
B.608 PL Plutella xylostella B.638 PL Oscinella spp.
B.609 PL Scirpophaga spp. B.639 PL Phorbia spp.
B.610 PL Sesamia spp. B.640 PL Frankliniella spp.
B.611 PL Sparganothis spp. B.641 PL Thrips spp.
B.612 PL Spodoptera sFp. B.642 PL Srirtothrips aurantii
B.613 PL Tortrix spp. B.643 PL Aceria spp.
B.614 PL Trichoplusia ni B.644 PL Aculus spp.
B.615 PL Agrlotes spp. B.645 PL Brevipaipus spp.
B.616 PL Anthonomus B.646 PL Panonychus spp.
grandis B.647 PL Phyllocoptruta spp.
B.617 PL Curculio spp. B.648 PL Tetranychus spp.
B.618 PL Diabrotica balteata B.649 PL Heterodera spp.
B.619 PL Leptinotarsa spp. B.650 PL Meloidogyne spp.
B.620 PL Lissorhoptrus spp. B.651 XN Adoxophyes spp.
B.621 PL Otiorhynchus spp. B.652 XN Agrotis spp.
B.622 PL Aleurothrixus spp. B.653 XN Alabama
B.623 PL Aleyrodes spp. argillaceae
B.624 PL Aonidiella spp. B.654 XN Anticarsia
B.625 PL Aphididae spp. gemmatalis
B.626 PL Aphis spp. B.655 XN Chilo spp.
B.627 PL Bemisia tabaci B.656 XN Clysia ambiguella
B.628 PL Empoasca spp. B.657 XN Crocidolomia
B.629 PL Mycus spp. binotalis
B.630 PL Nephotettix spp. B.658 XN Cydia spp.
B.631 PL Nilaparvata spp. B.659 XN Diparopsis
B.632 PL Pseudococcus spp. castanea
B.633 PL Psylla.spp. B.660 XN Earias spp.
B.634 PL Quadraspidiotus B.661 XN Ephestia spp.
spp. B.662 XN Heliothis spp.
B.635 PL Schizaphis spp. B.663 XN Hellula undalis
B.636 PL Trialeurodes spp. B.664 XN Keiferia


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
- 75 -

AP Control of AP Control of
lycopersicella B.694 XN IVlycus spp.
B.665 XN Leucoptera scitelia B.695 XN Nephotettix spp.
B.666 XN Lithocollethis spp. B.696 XN Nilapanrata spp.
B.667 XN Lobesia botrana B.697 XN Pseudococcus spp.
B.668 XN Ostrinia nubilalis B.698 XN Psylla spp.
B.6i~9 XN Pandemis spp. B.699 XN Quadraspidiotus
B.670 XN Pectinophora spp.
gossyp. B.700 XN Schizaphis spp.
B.671 XN Phyllocnistis citrella B.701 XN Trialeurodes spp.
B.672 XN Pieris spp. B.702 XN Lyriomyza spp.
B.673 XN Plutella xyiostelia B.703 XN Oscinella spp.
B.674 XN Scirpophaga spp. B.704 XN Phorbia spp.
B.675 XN Sesamia spp. B.705 XN Frankliniella spp.
B.676 XN Sparganothis spp. B.706 XN Thrips spp.
B.677 XN Spodoptera spp. B.707 XN Scirtothrips aurantii
B.678 XN Tortrix spp. B.708 XN Aceria spp.
B.679 XN Trichoplusia ni B.709 XN Aculus spp.
B.680 XN Agriotes spp. B.710 XN Brevipaipus spp.
B.681 XN Anthonomus B.71 l XN Panonychus spp.
grandis B.712 XN Phyllocoptruta spp.
B.682 XN Curculio spp. B.713 XN Tetranychus spp.
B.683 XN Diabrotica balteata B.714 XN Heterodera spp.
B.684 XN Leptinotarsa spp. B.715 XN Meloidogyne spp.
B.685 XN Lissorhoptrus spp. B.716 Plnh. Adoxophyes spp.
B.686 XN Otiorhynchus spp. B.717 Pinh. Agrotis spp.
B.687 XN Aleurothrixus spp. B.718 Plnh. Alabama
B.688 XN Aleyrodes spp. argillaceae
B.689 XN Aonidiefia spp. B.719 Pinh. Anticarsia
B.690 XN Aphididae spp. gemmatalis
B.691 XN Aphis spp. B.720 Ptnh. Chilo spp.
B.692 XN Bemisia tabaci B.721 Pinh. Clysia ambiguella
B.693 XN Empoasca spp. B.722 Plnh. Crocidolomia


CA 02317050 2000-06-27

WO 9955913 PCT/EP99/00183
- 76 -

AP Control of AP Control of
binotalis B.750 Plnh. Lissorhoptrus spp.
B.723 Plnh. Cydia spp. B.751 Pinh. Otiorhynchus spp.
B.724 Plnh. Diparopsis B.752 Pinh. Aleurothrixus spp.
castanea B.753 Pinh. Aleyrodes spp.
B.725 Pinh. Earias spp. B.754 Plnh. Aonidiella spp.
B.726 Pinh. Ephestia spp. B.755 Plnh. Aphididae spp.
B.727 Plnh. Heliothis spp. B.756 Pinh. Aphis spp.
B.728 Plnh. Hellula undalis B.757 Plnh. Bemisia tabaci
B.729 Pinh. Keiferia B.758 Pinh. Empoasca spp.
lycopersicella B.759 Pinh. Mycus spp.
B.730 Pinh. Leucoptera scitella B.760 Pinh. Nephotettix spp.
B.731 Pinh. Lithocollethis spp. B.761 Pinh. Nilaparvata spp.
B.732 Plnh. Lobesia botrana B.762 Plnh. Pseudococcus spp.
B.733 Pinh. Ostrinia nubilalis B.763 Plnh. Psylla spp.
B.734 Pinh. Pandemis spp. B.764 Plnh. Quadraspidiotus
B.735 Plnh. Pectinophora spP.
gossyp. B.765 Plnh. Schizaphis spp.
B.736 Pinh. Phyitocnistis citrella B.766 Pinh. Trialeurodes spp.
B.737 Plnh. Pieris spp. B.767 Plnh. Lyriomyza spp.
B.738 Pinh. Plutella xylostella B.768 Plnh. Oscinelia spp.
B.739 Plnh. Scirpophaga spp. B.769 Plnh. Phorbia spp.
B.740 Plnh. SeSamia spp. B.770 Plnh. Frankfiniella spp.
B.741 Pinh. Sparganothis spp. B.771 Pinh. Thrips spp.
B.742 Pinh. Spodoptera spp. B.772 Plnh. Scirtothrips aurantii
B.743 Pinh. Tortrix spp. B.773 Plnh. Aceria spp.
B.744 Plnh. Trichoplusia ni B.774 Plnh. Aculus spp.
B.745 Plnh. Agriotes spp. B.775 Plnh. Brevipaipus spp.
B.746 Pinh. Anthonomus B.776 Pinh. Panonychus spp.
grandis B.777 Pinh. Phyllocoptruta spp.
B.747 Pinh. Curculio spp. B.778 Pinh. Tetranychus spp.
B.748 Pinh. Diabrotica balteata B.779 Pinh. Heterodera spp.
B.749 Pinh. Leptinotarsa spp. B.780 Pinh. Meloidogyne spp.


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
-n-
AP Control of AP Control of

B.781 PLec. Adoxophyes spp. B.807 PLec. Spodoptera spp.
B.782 PLec. Agrotis spp. B.808 PLec. Tortrix spp.
B.783 PLec. Alabama B.809 PLec. Trichoplusia ni
argillaceae B.810 PLec. Agriotes spp.
B.784 PLec. Anticarsia B.811 PLec. Anthonomus
gemmatalis gmndis
B.785 PLec. Chito spp. B.812 PLec. Curculio spp.
B.786 PLec. Clysia ambiguella B.813 PLec. Diabrotica balteata
B.787 PLec. Crocidolomia B.814 PLec. Leptinotarsa spp.
binotalis B.815 PLec. Lissorhoptrus spp.
B.788 PLec. Cydia spp. B.816 PLec. Otiorhynchus spp.
B.789 PLec. Diparopsis B.817 PLec. Aleurothrixus spp.
castanea B.818 PLec. Aleyrodes spp.
B.790 PLec. Earias spp. B.819 PLec. Aonidielia spp.
B.791 PLec. Ephestia spp. B.820 PLec. Aphididae spp.
B.792 PLec. Heliothis spp. B.821 PLec. Aphis spp.
B.793 PLec. Hellula undalis B.822 PLec. Bemisia tabaci
B.794 PLec. Keiferia B.823 PLec. Empoasca spp.
lycopersicelia B.824 PLec. Mycus spp.
B.795 PLec. Leucoptera scitelia B.825 PLec. Nephotettix spp.
B.796 PLec. Lithocollethis spp. B.826 PLec. Nilaparvata spp.
B.797 PLec. Lobesia botrana B.827 PLec. Pseudococcus spp.
B.798 PLec. Ostrinia nubilalis B.828 PLec. Psylia spp.
B.799 PLec. Pandemis spp. B.829 PLec. Ouadraspidiotus
B.800 PLec. Pectinophora sPP=
gossyp. B.830 PLec. Schizaphis spp.
B.801 PLec. Phyllocnistis citrella B.831 PLec. Trialeurodes spp.
B.802 PLec. Pieris spp. B.832 PLec. Lyriomyza spp.
B.803 PLec. Plutetla xylosteQa B.833 PLec. Oscinelia spp.
B.804 PLec. Scirpophaga spp. B.834 PLec. Phorbia spp.
B.805 PLec. Sesamia spp. B.835 PLec. Franklinielia spp.
B.806 PLec. Sparganothis spp. B.836 PLec. Thrips spp.


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
-78-
AP Controi of AP Control of

B.837 PLec. Scirtothrips aurantii B.864 Aggi. Pandemis spp.
B.838 PLec. Aceria spp. B.865 Aggl. Pecqnophora
B.839 PLec. Aculus spp. gossyp-
B.840 PLec. Brevipalpus spp. B.866 Aggl. Phyllocnistis citrelia
B.841 PLec. Panonychus spp. B.867 Aggl. Pieris spp.
B.842 PLec. PhyNo%-.ptruta spr. B.868 Aggi. Pluteiis xylostelia
B.843 PLec. Tetranychus spp. B.869 Aggi. Scirpophaga spp.
B.844 PLec. Heterodera spp. B.870 Aggi. Sesamia spp.
B.845 PLec. Meloidogyne spp. B.871 Aggi. Sparganothis spp.
B.846 Aggi. Adoxophyes spp. B.872 Aggi. Spodoptera spp.
B.847 Aggi. Agrotis spp. B.873 Aggi. Tortrix spp.
B.848 Aggl. Alabama B.874 Aggi. Trichoplusia ni
argillaceae B.875 Aggi. Agriotes spp.
B.849 Aggl. Anticarsia B.876 Aggi. Anthonomus
gemmatalis grandis
B.850 Aggl. Chilo spp. B.877 Aggi. Curcuiio spp.
B.851 Aggl. Clysia ambiguella B.878 Aggi. Diabrotica balteata
B.852 Aggi. Crocidolomia B.879 Aggl. Leptinotarsa spp.
binotalis B.880 Aggi. Lissorhoptrus spp.
B.853 Aggi. Cydia spp. B.881 Aggi. Otiorhynchus spp.
B.854 Aggi. Diparopsis B.882 Aggl. Aleurothrixus spp.
castanea B.883 Aggi. Aleyrodes spp.
B.855 Aggi. Earias spp. B.884 Aggi. Aonidielia spp.
B.856 Aggi. Ephestia spp. B.885 Aggl. Aphididae spp.
B.857 Aggi. Hetiothis spp. B.886 Aggi. Aphis spp.
B.858 Aggl. Hellula undalis B.887 Aggi. Bemisia tabaci
B.859 Aggi. Keiferia B.888 Aggi. Empoasca spp.
lycopersicella B.889 Aggi. Mycus spp.
B.860 Aggi. Leucoptera scitella B.890 Aggi. Nephotettix spp.
B.861 Aggi. Lithocollethis spp. B.891 Aggi. Nilaparvata spp.
B.862 Aggl. Lobesia botrana B.892 Aggi. Pseudococcus spp.
B.863 Aggi. Ostrinia nubilalis B.893 Aggi. Psyfia spp.


CA 02317050 2000-06-27

WO 99/35913 PCT/EP99/00183
-79-
AP Control of AP Control of

B.894 Aggi. C.luadraspidiotus B.921 CO Ephestia spp.
spp. B.922 CO Heliothis spp.
B.895 Aggi. Schizaphis spp. B.923 CO Hellula undalis
B.896 Aggl. Trialeurodes spp. B.924 CO Ke'rferia
B.897 Aggi. Lyriomyza app. iycopen3icelia
B.898 ' Aggi. Oscinella app. B.925 CO Leucoptera scitella
B.899 Aggl. Phorbia spp. B.926 CO Lithocollethis spp.
B.900 Aggl. Frankliniella spp. B.927 CO Lobesia botrana
B.901 Aggl. Thrips spp. B.928 CO Ostrinia nubilalis
B.902 Aggl. Scirtothrips aurantii B.929 CO Pandemis spp.
B.903 Aggi. Aceria spp. B.930 CO Pectinophora
B.904 Aggi. Aculus spp. gossyp.
B.905 Aggl. Brevipatpus spp. B.931 CO Phyllocnistis citrella
B.906 Aggt. Panonychus spp. B.932 CO Pieris spp.
B.907 Aggi. Phyllocoptruta spp. B.933 CO Plutella xylostelia
B.908 Aggl. Tetranychus spp. B.934 CO Scirpophaga spp.
B.909 Aggl. Heterodera spp. B.935 CO Sesamia spp.
B.910 Aggl. Meloidogyne spp. B.936 CO Sparganothis spp.
B.911 CO Adoxophyes spp. B.937 CO Spodoptera spp.
B.912 CO Agrotis spp. B.938 CO Tortrix spp.
B.913 CO Alabama B.939 CO Trichoplusia ni
argillaceae B.940 CO Agriotes spp.
B.914 CO Anticarsia B.941 CO Anthonomus
gemmatalis grandis
B.915 CO Chilo spp. B.942 CO Curculio spp.
B.916 CO Clysia ambiguelia B.943 CO Diabrotica balteata
B.917 CO Crocidolomia B.944 CO Leptinotarsa spp.
binotalis B.945 CO Lissorhoptrus spp.
B.918 CO Cydia spp. B.946 CO Otiorhynchus spp.
B.919 CO Diparopsis B.947 CO Aleurothrixus spp.
castanea B.948 CO Aleyrodes spp.
B.920 CO Earias spp. B.949 CO Aonidiella spp.


CA 02317050 2000-06-27
WO 99/35913 PCT/EP99/00183
-80-
AP Control of AP Control of

B.950 CO Aphididae spp. gemmataiis
B.951 CO Aphis spp. B.980 CH Chilo spp.
B.952 CO Bemisia tabaci B.981 CH Clysia ambiguella
B.953 CO Empoasca spp. B.982 CH Crocidolomia
B.954 CO Mycus spp. binotalis
B.955 CO NephotettiX spp. B.983 CH Cydia spp.
B.956 CO Nilaparvata spp. B.984 CH Diparopsis
B.957 CO Pseudococcus spp. castanea
B.958 CO Psylia spp. B.985 CH Earias spp.
B.959 CO Quadraspidiotus B.986 CH Ephestia spp.
spp. B.987 CH Heliothis spp.
B.960 CO Schizaphis spp. B.988 CH Helluia undalis
B.961 CO Trialeurodes spp. B.989 CH Keiferia
B.962 CO Lyriomyza spp. iycopersicella
B.963 CO Oscinella spp. B.990 CH Leucoptera scitelia
B.964 CO Phorbia spp. B.991 CH LithocoUethis spp.
B.965 CO Franklinielia spp. B.992 CH Lobesia botrana
B.966 CO Thrips spp. B.993 CH Ostrinia nubilaiis
B.967 CO Scirtothrips aurantii B.994 CH Pandemis spp.
B.968 CO Aceria spp. B.995 CH Pectinophora
B.969 CO Aculus spp. gossyp.
B.970 CO Brevipalpus spp. B.996 CH Phyllocnistis citrelia
B.971 CO Panonychus spp. B.997 CH Pieris spp.
B.972 CO Phyllocoptruta spp. B.998 CH Plutella xylostella
B.973 CO Tetranychus spp. B.999 CH Scirpophaga spp.
B.974 CO Heterodera spp. B.1000 CH Sesamia spp.
B.975 CO Meloidogyne spp. B.1001 CH Sparganothis spp.
B.976 CH Adoxophyes spp. B.1002 CH Spodoptera spp.
B.977 CH Agrotis spp. B.1003 CH Tortrix spp.
B.978 CH Alabama B.1004 CH Trichoplusia ni
argillaceae B.1005 CH Agriotes spp.
B.979 CH Anticarsia B.1006 CH Anthonomus


CA 02317050 2000-06-27
WO 99/35913 PCT/EP99/00183
. g~ .

AP Control of AP Control of

grandis B.1037 CH Phyllocoptruta spp.
B.1007 CH Curculio spp. B.1038 CH Tetranychus spp.
B.1008 CH Diabrotica balteata B.1039 CH Heterodera spp.
B.1009 CH Leptinotarsa spp. B.1040 CH Meloidogyne spp.
B.1010 CH Lissorhoptrus spp. B.1041 SS Adoxophyes spp.
B.1011 CH Otiorhynohus app. B.1042 SS Agrotis spp.
B.1012 CH Aleurothrixus spp. B. 1043 SS Alabama
B.1013 CH Aleyrodes spp. argillaceae
B.1014 CH Aonidielia spp. B.1044 SS Anticarsia
B.1015 CH Aphididae spp. gemmatalis
B.1016 CH Aphis spp. B.1045 SS Chilo spp.
B.1017 CH Bemisia tabaci B.1046 SS Clysia ambiguella
B.1018 CH Empoasca spp. B.1047 SS Crocidolomia
B.1019 CH Mycus spp. binotalis
B.1020 CH Nephotettix spp. B.1048 SS Cydia spp.
B.1021 CH Nilaparvata spp. B.1049 SS Diparopsis
B.1022 CH Pseudococcus spp. castanea
B.1023 CH Psylla spp. B.1050 SS Earias spp.
B.1024 CH Quadraspidiotus B.1051 SS Ephestia spp.
spp. B.1052 SS Heliothis spp.
B.1025 CH Schizaphis spp. B.1053 SS Hellula undalis
B.1026 CH Trialeurodes spp. B.1054 SS Keiferia
B.1027 CH Lyriomyza spp. lycopersicella
B.1028 CH Oscinella spp. B.1055 SS Leucoptera scitella
B.1029 CH Phorbia spp. B.1056 SS Lithocollethis spp.
B.1030 CH Franklinielia spp. B.1057 SS Lobesia botrana
B. 1031 CH Thrips spp. B.1058 SS Ostrinia nubilalis
B.1032 CH Scirtothrips aurantii B.1059 SS Pandemis spp.
B.1033 CH Aceria spp. B.1060 SS Pectinophora
B.1034 CH Aculus spp. gossyp.
B.1035 CH Brevipatpus spp. B.1061 SS Phyllocnistis citrelia
B.1036 CH Panonychus spp. B.1062 SS Pieris spp.


CA 02317050 2000-06-27

WO 99/35913 P~~~~193
-82-
AP Control of AP Control of

B.1063 SS Plutelia xylosteiia B.1093 SS Oscinelia spp.
B.1064 SS Scirpophaga spp. B.1094 SS Phorbia spp.
B.1065 SS Sesamia spp. B.1095 SS Franklinielia spp.
B.1066 SS Sparganothis spp. B.1096 SS Thrips spp.
B.1067 SS Spodoptera spp. B. 1097 SS Scirtothrips aurantii
B.1068 SS Tortrix spp. B.1093 SS ~ Aceria spp.
B.1069 SS Trichopiusia ni B.1099 SS Aculus spp.
B.1070 SS Agriotes spp. B. 1100 SS Brevipaipus spp.
B.1071 SS Anthonomus B.1101 SS Panonychus spp.
grandis B.1102 SS Phyllocoptruta spp.
B.1072 SS Curculio spp. B.1103 SS Tetranychus spp.
B.1073 SS Diabrotica balteata B.1104 SS Heterodera spp.
B.1074 SS Leptinotarsa spp. B.1105 SS Meloidogyne spp.
B.1075 SS Lissorhoptrus spp. B.1106 HO Adoxophyes spp.
B.1076 SS Otiorhynchus spp. B.1107 HO Agrotis spp.
B.1077 SS Aleurothrixus spp. B.1108 HO Alabama
B.1078 SS Aleyrodes spp. argillaceae
B.1079 SS Aonidielia spp. B. 1109 HO Anticarsia
B. 1080 SS Aphididae spp. gemmatalis
B.1081 SS Aphis spp. B.1110 HO Chilo spp.
B.1082 SS Bemisia tabaci B.1111 HO Clysia ambiguella
B.1083 SS Empoasca spp. B.1112 HO Crocidolomia
B.1084 SS Mycus spp. binotalis
B. 1085 SS Nephotettix spp. B.1113 HO Cydia spp.
B.1086 SS Nilaparvata spp. B.1114 HO Diparopsis
B. 1087 SS Pseudococcus spp. castanea
B.1088 SS Psylla spp. B.1115 HO Eartas spp.
B.1089 SS Gluadraspidiotus B.1116 HO Ephestia spp.
spp. B.1117 HO Heliothis spp.
B.1090 SS Schizaphis spp. B.1118 HO Hellula undalis
B.1091 SS Trialeurodes spp. B.1119 HO Keiferia
B.1092 SS Lyriomyza spp. iycopersicella


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AP Control of AP Control of

B.1120 HO Leucoptera scitella B.1145 HO Aphididae spp.
B.1121 HO Lithocollethis spp. B.1146 HO Aphis spp.
B.1122 HO Lobesia botrana B.1147 HO Bemisia tabaci
B.1123 HO Ostrinia nubilalis B.1148 HO Empoasca spp.
B.1124 HO Pandemis spp. B.1149 HO Mycus spp.
B.1125 HO Pectinophora B. 1150 HO Nephotettix spp.
gossypiella B.1151 HO Nilaparvata spp.
B.1126 HO Phyllocnistis citrella B. 1152 HO Pseudococcus spp.
B.1127 HO Pieris spp. B.1153 HO Psylia spp.
B. 1128 HO Plutella xylostella B.1154 HO Quadraspidiotus
B.1129 HO Scirpophaga spp. spp.
B.1130 HO Sesamia spp. B.1155 HO Schizaphis spp.
B.1131 HO Sparganothis spp. B.1156 HO Trialeurodes spp.
B.1132 HO Spodoptera spp. B.1157 HO Lyriomyza spp.
B.1133 HO Tortrix spp. B.1158 HO Oscinella spp.
B.1134 HO Trichoplusia ni B.1159 HO Phorbia spp.
B:1135 HO Agriotes spp. B.1160 HO Frankliniella spp.
B.1136 HO Anthonomus B.1161 HO Thrips spp.
grandis B.1162 HO Scirtothrips aurantii
B.1137 HO Curculio spp. B.1163 HO Aceria spp.
B.1138 HO Diabrotica balteata B.1164 HO Aculus spp.
B.1139 HO Leptinotarsa spp. B.1165 HO Brevipaipus spp.
B.1140 HO Lissorhoptrus spp. B.1166 HO Panonychus spp.
B.1141 HO Otiorhynchus spp. B.1167 HO Phyllocoptruta spp.
B.1142 HO Aleurothrixus spp. B.1168 HO Tetranychus spp.
B.1143 HO Aleyrodes spp. B.1169 HO Heterodera spp.
B.1144 HO Aonidiella spp. B.1170 HO Meloidogyne spp.
Biological Examiples

Table 1: A method of controlling pests comprising the application of
thiamethoxam to
transgenic cotton, wherein the combination of the active principle expressed
by the


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transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Tablg2: A method of controlling pests comprising the application of
thiamethoxam to
transgenic rice, wherein the combination of the active principle expressed by
the transgenic
plant and the pest to be controlled correspond to anyone of the individuaGsed
combinations
B.1 to B.1170 of table B.

Table 3: A method of controlling pests comprising the application of
thiamethoxam to
transgenic potatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 4: A method of controlling pests comprising the application of
thiamethoxam to
transgenic brassica, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 5: A method of controlling pests comprising the apptication of
thiamethoxam to
transgenic tomatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Table 6: A method of controlling pests comprising the application of
thiamethoxam to
transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 7: A method of controlling pests comprising the application of
thiamethoxam to
transgenic soybeans, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Table 8: A method of controlling pests comprising the application of
thiamethoxam to
transgenic maize, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.


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Table 9: A method of controlling pests comprising the application of
thiamethoxam to
transgenic wheat, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Table 10: A method of controlling pests comprising the application of
thiamethoxam to
transgenic bananas, wherein the combination of the active principle expressed
by the
transgenic piant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 11: A method of controlling pests comprising the application of
thiamethoxam to
transgenic citrus trees, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to anyone of the
individuaiised
combinations B.1 to B.1 170 of table B.

Table 12: A method of controlling pests comprising the application of
thiamethoxam to
transgenic pome fruit trees, wherein the combination of the active principle
expressed by
the transgenic plant and the pest to be controlled correspond to anyone of the
individualised combinations B.1 to B.1170 of table B.

Table 13: A method of controlling pests comprising the application of
thiamethoxam to
transgenic peppers, wherein the combination of the'active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 14: A method of controlling pests comprising the application of
imidacioprid to
transgenic cotton, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

J'abie 15: A method of controlling pests comprising the application of
imidacloprid to
transgenic rice, wherein the combination of the active principle expressed by
the transgenic
plant and the pest to be controlled correspond to anyone of the individualised
combinations
B.1 to B.1170 of table B.

T ba le 16: A method of controlling pests comprising the application of
imidacloprid to
transgenic potatoes, wherein the combination of the active principle expressed
by the


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transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Table 17: A method of controlling pests comprising the application of
imidadoprid to
transgenic tomatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

TabIe 18: A method of controlling pests comprising the application of
imidacloprid to
transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Table 19: A method of controlling pests comprising the application of
imidaeloprid to
transgenic soybeans, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Table 20: A method of controlling pests comprising the application of
imidacloprid to
transgenic maize, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Table 21: A method of controlling pests comprising the application of
imidacioprid to
transgenic wheat, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B. 1170 of table B.

Table 22: A method of controlling pests comprising the appGcation of
imidacloprid to
transgenic bananas, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individuabsed
combinations B.1 to B.1170 of table B.

Table 23: A method of controlling pests comprising the application of
imidacioprid to
transgenic orange trees, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.


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Table 24: A method of controlling pests comprising the application of
imidacloprid to
transgenic pome fruit, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 25: A method of controlling pests comprising the appfication of
imidacloprid to
transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond,to anyone of the
individuaiised
combinations B.1 to B.1170 of table B.

Table 26: A method of controlling pests comprising the application of
imidacioprid to
transgenic peppers, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Tabie 27: A method of controlling pests comprising the application of Ti-435
to transgenic
cotton, wherein the combination of the active principle expressed by the
transgenic plant
and the pest to be controlled correspond to anyone of the individuallsed
combinations B.1
to B.1170 of table B.

Table 28: A method of controifing pests comprising the application of Ti-435
to transgenic
rice, wherein the combination of the active principle expressed by the
transgenic plant and
the pest to be controlled correspond to anyone of the individualised
combinations B.1 to
B.1170 of table B.

Table 29: A method of controlling pests comprising the application of Ti-435
to transgenic
potatoes, wherein the combination of the active principie expressed by the
transgenic plant
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1170 of table B.

Table 30: A method of controlling pests comprising the application of Ti-435
to transgenic
brassica, wherein the combination of the active principle expressed by the
transgenic plant
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1170 of table B.

Table 31: A method of controlling pests comprising the application of Ti-435
to transgenic
tomatoes, wherein the combination of the active principle expressed by the
transgenic plant


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.gg.
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1170 of table B.

T I 32: A method of controlling pests comprising the apptication of Twt35 to
transgenic
cucurbits, wherein the combination of the active principle expressed by the
tmnsgenic plant
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1170 of table B.

T I 33: A method of controlling pests comprising the apptication of Ti-435 to
transgenic
soybeans, wherein the combination of the active principle expressed by the
transgenic plant
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1170 of table B.

T I 34: A method of controiiing pests comprising the application of Ti-435 to
transgenic
maize, wherein the combination of the active pdnciple expressed by the
transgenic plant
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1 170 of table B.

Ta I 35: A method of controlling pests comprising the application of Ti-435 to
transgenic
wheat, wherein the combination of the active principle expressed by the
transgenic plant
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1170 of table B.

Table 36: A method of controlling pests comprising the application of Ti-435
to transgenic
bananas, wherein the combination of the active principle expressed by the
transgenic plant
and the pest to be controlled correspond to anyone of the individualised
combinations B.1
to B.1 170 of table B.

T I 37: A method of controlling pests comprising the application of Ti-435 to
transgenic
citrus trees, wherein the combination of the active principle expressed by the
transgenic
plant and the pest to be controlled correspond to anyone of the individualised
combinations
B.1 to B.1170 of table B.

Table 38: A method of controlling pests comprising the application of Ti-435
to transgenic
pome fruit trees, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.


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Table 39: A method of controlling pests comprising the application of
thiacloprid to
transgenic cotton, wherein the combination of the activve principle expressed
by the
transgenic plant and the pest to be controlled c:orrespond to anyone of the
individuatised
combinations B.1 to B.1 170 of table B.

Table 40: A method of controlting pests comprising the application of
thiacloprid to
transgenic rice, wherein the combination of the active principle expressed by
the transgenic
plant and the pest to be controlled correspond to anyone of the individualised
combinations
B.1 to B.1170 of table B.

Table 41: A method of controlling pests comprising the application of
thiacloprid to
transgenic potatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 42: A method of controlling pests comprising the application of
thiacloprid to
transgenic brassica, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

T ba ie 48: A method of controlling pests comprising the application of
thiacloprid to
transgenic tomatoes, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individuaiised
combinations B.1 to B.1 170 of table B.

Table 44: A method of controlling pests comprising the application of
thiacloprid to
transgenic cucurbits, wherein the combination of the active principle
expressed by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1 170 of table B.

Table 45: A method of controlling pests comprising the application of
thiacloprid to
transgenic soybeans, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Ta I 46: A method of controlling pests comprising the application of
thiacloprid to
transgenic maize, wherein the combination of the active principle expressed by
the


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transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

T I 47: A method of controlling pests comprising the application of
thlacioprid to
transgenic wheat, wherein the combination of the active principle expressed by
the
transgenic plant and the pest to be controlled correspond to anyone of the
individualised
combinations B.1 to B.1170 of table B.

Ta I 48: A method of controlling pests comprising the appiication of
thiactoprid to
transgenic bananas, wherein the combination of the active principle expressed
by the
transgenic plant and the pest to be controlled correspond to anyone of the
individuaiised
combinations B.1 to B.1 170 of table B.

Table C:
Abbreviations:
Acetyl-COA Carboxylase: ACCase
Acetolactate Synthase: ALS
Hydroxyphenylpyruvat dioxygenase: HPPD
Inhibition of protein synthesis: IPS
Hormone mimic: HO
Glutamine Synthetase: GS
Protoporphyrinogen oxidase: PROTOX
5-Enolpyruvyl-3-Phosphoshikimate Synthase: EPSPS

Principle Tolerant to Crop
C.1 ALS Sulfonylureas etc."' Cotton
C.2 ALS Sulfonylureas etc. Rice
C.3 ALS Sulfonylureas etc. Brassica
C.4 ALS Sulfonylureas etc. Potatoes
C.5 ALS Sulfonyiureas etc. Tomatoes
C.6 ALS Suifonylureas etc. Cucurbits
C.7 ALS Sulfonylureas etc. Soybeans
C.8 ALS Sulfonylureas etc. Maize
C.9 ALS Sulfonylureas etc. Wheat
C.10 ALS Sulfonylureas etc. pome fruit


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Principle Tolerant to Crop

C.11 ALS Sulfonylureas etc. stone fruit
C.12 ALS Sutfonytureas etc. citrus
C.13 ACCase +++ Cotton
C.14 ACCase +++ Rice
C.15 ACCase +++ Brassica
C.16 ACCase +++ Potatoes
C.17 ACCase +++ Tomatoes
C.18 ACCase +++ Cucurbits
C.19 ACCase +++ Soybeans
C.20 ACCase +++ Maize
C.21 ACCase +++ Wheat
C.22 ACCase +++ pome fruit
C.23 ACCase +++ stone fruit
C.24 ACCase Hi citrus
C.25 HPPD Isoxaflutol, Isoxachiotol, Sutcotrion, Mesotrion Cotton
C.26 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Rice
C.27 HPPD Isoxaftutol, Isoxachlotot, Sulcotrion, Mesotrion Brassica
C.28 HPPD lsoxaflutol, isoxachlotol, Sulcotrion, Mesotrion Potatoes
C.29 HPPD Isoxaftutol, lsoxachlotol, Sulcotrion, Mesotrion Tomatoes
C.30 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Cucurbits
C.31 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Soybeans
C.32 HPPD lsoxafiutol, lsoxachlotol, Sulcotrion, Mesotrion Maize
C.33 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion Wheat
C.34 HPPD tsoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion pome fruit
C.35 HPPD Isoxaflutol, lsoxachlotol, Sulcotrion, Mesotrion stone fruit
C.36 HPPD lsoxaflutol, Isoxachiotol, Sulcotrion, Mesotrion citrus
C.37 Nitrilase Bromoxynil, loxynil Cotton
C.38 Nitrilase Bromoxynil, loxynil Rice
C.39 Nitrilase Bromoxynil, loxynil Brassica
C.40 Nitritase Bromoxynil, loxynil Potatoes
C.41 Nitrilase Bromoxynil, loxynil Tomatoes
C.42 Nitriiase Bromoxynil, loxynil Cucurbits


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Principle Toierant to Crop

C.43 Nitrilase Bromoxynil, loxynil Soybeans
C.44 Nitrilase Bromoxynil, loxynil Maize
C.45 Nitrilase Bromoxynii, loxynil Wheat
C.46 Nitrilase Bromoxynil, loxynil pome fruit
C.47 Nitrilase Bromoxynil, loxynil stone fruit
C.48 Nitrilase Bromoxynil, loxynil citrus
C.49 IPS Chloroactanilides &&& Cotton
C.50 IPS Chloroactanilides &&& Rice
C.51 IPS Chloroactanilide &&&s Brassica
C.52 IPS Chloroactanilides &&& Potatoes
C.53 IPS Chloroactanilides &&& Tomatoes
C.54 IPS Chloroactanilides &&& Cucurbits
C.55 IPS Chloroactanilides &&& Soybeans
C.56 IPS Chloroactanilides &&& Maize
C.57 IPS Chioroactanilides &&& Wheat
C.58 IPS Chloroactanilides &&& pome fruit
C.59 IPS Chioroactanilides &&& stone fruit
C.60 IPS Chloroactanilides &&& citrus
C.61 HOM 2,4-D, Mecoprop-P Cotton
C.62 HOM 2,4-D, Mecoprop-P Rice
C.63 HOM 2,4-D, Mecoprop-P Brassica
C.64 HOM 2,4-D, Mecoprop-P Potatoes
C.65 HOM 2,4-D, Mecoprop-P Tomatoes
C.66 HOM 2,4-D, Mecoprop-P Cucurbits
C.67 HOM 2,4-D, Mecoprop-P Soybeans
C.68 HOM 2,4-D, Mecoprop-P Maize
C.69 HOM 2,4-D, Mecoprop-P Wheat
C.70 HOM 2,4-D, Mecoprop-P pome fruit
C.71 HOM 2,4-D, Mecoprop-P stone fruit
C.72 HOM 2,4-D, Mecoprop-P citrus
C.73 PROTOX Protox inhibitors Il/ Cotton
C.74 PROTOX Protox inhibitors Il/ Rice


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Principle Tolerent to Crop

C.75 PROTOX Protox inhibitors Brassica
C.76 PROTOX Protox inhibitors /// Potatoes
C.77 PROTOX Protox inhibitors /// Tomatoes
C.78 PROTOX Protox inhibitors /// Cucurbits
C.79 PROTOX Protox inhibitors Ill Soybeans
C.80 PROTOX Protox inhibitors Maize
C.81 PROTOX Protox inhibitors Wheat
C.82 PROTOX Protox inhibitors /// pome fruit
C.83 PROTOX Protox inhibitors IlI stone truit
C.84 PROTOX Protox inhibitors citrus
C.85 EPSPS Glyphosate and /or Suiphosate Cotton
C.86 EPSPS Glyphosate and /or Suiphosate Rice
C.87 EPSPS Glyphosate and /or Sulphosate Brassica
C.88 EPSPS Glyphosate and /or Suiphosate Potatoes
C.89 EPSPS Glyphosate and /or Sulphosate Tomatoes
C.90 EPSPS Glyphosate and /or Sutphosate Cucurbits
C.91 EPSPS Glyphosate and /or Sulphosate Soybeans
C.92 EPSPS Glyphosate and. /or Sulphosate Maize
C.93 EPSPS Glyphosate and /or Sulphosate Wheat
C.94 EPSPS Glyphosate and /or Suiphosate pome fruit
C.95 EPSPS Glyphosate and /or Sulphosate stone fruit
C.96 EPSPS Giyphosate and /or Sulphosate citrus
C.97 GS Gluphosinate and /or Bialaphos Cotton
C.98 GS Gluphosinate and /or Bialaphos Rice
C.99 GS Gluphosinate and /or Bialaphos Brassica
C.100 GS Gluphosinate and /or Bialaphos Potatoes
C.101 GS Gluphosinate and /or Bialaphos Tomatoes
C.102 GS Gluphosinate and /or Bialaphos Cucurbits
C.103 GS Giuphosinate and /or Bialaphos Soybeans
C.104 GS Gluphosinate and /or Bialaphos Maize
C.105 GS Gluphosinate and /or Bialaphos Wheat
C. 106 GS Gluphosinate and /or Bialaphos pome fruit


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Principie Tolerant to Crop

C.107 GS Gluphosinate and /or Bialaphos stone fruit
C.108 GS Gluphosinate and /or Bialaphos citrus

Included are Sulfonylureas, imidazolinones, Triazolopyrimidines,
Dimethoxypyrimidines
and N-Acylsutfonamides:
Sulfonylureas such as Chiorsulfuron, Chlorimuron, Ethamethsulturon,
IVletsulfuron,
Primisuifuron, Prosulfuron, Triasulfuron, Cinosulfuron, Trifusulfuron,
Oxasulfuron,
Bensulfuron, Tribenuron, ACC 322140, Fluzasulfuron, Ethoxysuifuron,
Fluzasdulfuron,
Nicosulfuron, Rimsulfuron, Thifensulfuron, Pyrazosulfuron, Clopyrasutfuron, NC
330,
Azimsulfuron, Imazosulfuron, Sulfosutfuron, Amidosulfuron, Flupyrsulfuron, CGA
362622
Imidazolinones such as Imazamethabenz, Imazaquin, tmazamethypyr, imazethapyr,
imazapyr and Imazamox;

Triazolopyrimidines such as DE 511, Flumetsulam and Chioransutam;
Dimethoxypyrimidines such as Pyrithiobac, Pyriminobac, Bispyribac and
Pyribenzoxim.
+++ Tolerant to Diciofop-methyi, Fluazifop-P-butyt, Haloxyfop-P-methyl,
Haioxytop-P-ethyl,
Quizalaf op-P-ethyl , clodinafop propargyl, fenoxaprop - -ethyl, -
Tepraloxydim, Alioxydim,
Sethoxydim, Cycloxydim, Cloproxydim, Tralkoxydim, Butoxydim, Caloxydim,
Ciefoxydim,
Clethodim.

&&& Chioroacetaniiides such as Atachlor Acetochior, Dimethenamid

lll Protox inhibitors: For instance diphenyethers such as Acifluorfen,
Aclonifen, Bitenox,
Chlomitrofen, Ethox}rfen, Fluorogiycofen, Fomesafen, Lactoten, Oxyfluorfen;
Imides such
as Azafenidin, Carfentrazone-ethyl, Cinidon-ethyt, Flumiclorac-pentyl,
Flumioxazin,
Fluthiacet-methyl, Oxadiargyl, Oxadiazon, Pentoxazone, Sulfentn3zone, Imides
and
others,such as Flumipropyn, Flupropacil, Nipyraciofen and Thidiazimin; and
further
Fluazolate and Pyraflufen-ethyl

Biological Examales

Table 49: A method of controlling representatives of the genus Adoxophyes
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the

.'_


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combination of the active principle expressed by the tmnsgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Ta I 50: A method of controiling representatives of the genus Agrotis
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the Gnes C.1 to C.108 of
table C.
Table 51: A method of controlling Alabama argillaceae comprising the
application of
thiamethoxam to a herbicidaliy resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 52: A method of controlling Anticarsia gemmatalis comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principie expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 53: A method of controlling representatives of the genus Chilo
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 54: A method of controlling Clysia ambiguelia comprising the application
of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

T le 55: A method of controlling representatives of the genus Cnephalocrocis
comprising
the application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 56: A method of controlling Crocidolomia binotalis comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.


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Table 57: A method of controlling representatives of the genus Cydia
comprising the
application of thiamethoxam to a herbicidaliy resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

T ba le 58: A method of controlling Diparopsis castanea comprising the
application of
thiamethoxam to a herbicidally resistant trensgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 59: A method of controlling represeritatives of the genus Earias
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
tabie C.
Table 60: A method of controlling representatives of the genus Ephestia
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 61: A method of controlling representatives of the genus Heliothis
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 62: A method of controlling Hellula undalis comprising the application
of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 63: A method of controlling Keiferia lycopersicelia comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic piant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 64: A method of controliing Leucoptera scitella comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the


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active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 65: A method of controlling representatives of the genus Lithocollethis
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C. 1 to C. 108 of
table C.

T b~66: A method of controlling Lobesia botrana comprising the application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 67: A method of controlling Ostrinia nubilalis comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle exNr4-csed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 68: A method of controlling representatives of the genus Pandemis
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 69: A method of controlling Pectinophora gossypielia comprising the
application of
thiamethoxam to a herbicidaiiy resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of tabie C.

Table 70: A method of controlling Phyllocnistis citrella comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 71: A method of controlling representatives of the genus Pieris
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.


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Table 72: A method of controlling PluteOa xylostelia comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Ta I 7: A method of controlling representatives of the genus Scirpophaga
comprising the
application of tr~~amethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active prir ple expressed by the transgenic plant and the
crop to be
protected against the pest correspond :o anyone of the lines C.1 to C.108 of
table C.
Table 74: A method of controlling representatives of the genus Sesamia
comprising the
application of thiamethoxam to a herbicidaAy resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the, lines C.1 to C.108 of
table C.

Table 75: A method of controlling representatives of the genus Sparganothis
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

T I 76: A method of controlling representatives of the genus Spodoptera
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the iines C.1 to C.1 08 of
table C.
Table 77: A method of controlling representatives ot the genus Tortrix
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 78: A method of controlling Trichoplusia ni comprising the application
of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 79: A method of controlling representatives of the genus Agriotes
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

T 80: A method of controlling Anthonomus grandis comprising the appiication of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Tabgt~1: A method of controlting representatives of the genus Curculio
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 82: A method of controlling Diabrotica balteata comprising the
application of
thiamethoxam to a herbicidaliy resistant transgenic crop, wherein the
combination ot the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 83: A method of controlling representatives of the genus Leptinotarsa
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 84: A method of controlling representatives of the genus Lissorhoptrus
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 85: A method of controlling representatives of the genus Otiorhynchus
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 86: A method of controlling representatives of the genus Aleurothrixus
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.


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ab 87: A method of controAing representatives of the genus Aleyrodes
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 88: A method of controlling representatives of the genus Aonidiella
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 89: A method of controlling representatives of the family Aphididae
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 90: A method of controlling representatives of the genus Aphis
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 91: A method of controlling Bemisia tabaci comprising the application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principie expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

T ba le 92: A method of controlling representatives of the genus Empoasca
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 93: A method of controlling representatives of the genus Mycus
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the iines C.1 to C.108 of
table C.
Table 94: A method of controlling representatives of the genus Nephotettix
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 95: A method of controlling representatives of the genus Nilaparvata
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.i to C.108 of
table C.
Table 96: A method of controlling representatives of the genus Pseudococcus
comprising
the application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 97: A method of controlling representatives of the genus Psylla
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 98: A method of controlling representatives of the genus Quadraspidiotus
comprising
the application of thiamethoxam to a herbicidaily resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 99: A method of controlling representatives of the genus Schizaphis
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic piant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 100: A method of controlling representatives of the genus Trialeurodes
comprising
the application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 101: A method of controlling representatives of the genus Lyriomyza
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.


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Table 102: A method of controlling representatives of the genus Oscinelia
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 103: A method of controlling representatives of the genus Phorbia
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principie expressed by the tranagenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 104: A method of controlling representatives of the genus Frankliniella
comprising the
application of thiamethoxam to w herbicidally resistant transgenic crop,
wherein the
combination of the active principle expreased by the transgenic plant and the
crop to be
protected against the pest correspond to anyone oi fhe lines C.1 to C.108 of
table C.

Table 105: A method of controlling representatives of the genus Thrips
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 106: A method of controlling Scirtothrips aurantii comprising the
application of
thiamethoxam to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 107: A method of controlling representatives of the genus Aceria
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 108: A method of controlling representatives of the genus Aculus
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 109: A method of controlling representatives of the genus Brevipaipus
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 11 : A method of controlling representatives of the genus Panonychus
comprising
the application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 111: A method of controlling representatives of the genus Phyllocoptruta
comprising
the application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.1 08 of
table C.
Table 112: A method of controlling representatives of the genus Tetranychus
comprising
the application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 113: A method of controlling representatives of the genus Heterodera
comprising the
application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 114: A method of controlling representatives of the genus Meloidogyne
comprising
the application of thiamethoxam to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 115: A method of controlling Mamestra brassica comprising the
application of
thiamethoxam to a herbicidatly resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 116: A method of controlling representatives of the genus Adoxophyes
comprising
the application of imidactoprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principie expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.1 08 of
table C.


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Table 117: A method of controlling- representatives of the genus Agrotis
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 118: A method of controlling Alabama argillaceae comprising the
application of
imidacioprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transganic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 119: A method of controlling Anticarsia gemmatatis comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 120: A method of controlling representatives of the genus Chilo
comprising the
application of imidacioprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 121: A method of controlling Clysia ambiguelia comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant. and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 122: A method of controlling representatives of the genus Cnephalocrocis
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 123: : A method of controlling Crocidolomia binotalis comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 124: A method of controlling representatives of the genus Cydia
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principie expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 125: A method of controlling Diparopsis castanea comprising the
appiication of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 126: A method of controlling representatives of the genus Earias
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 127: A method of controlling representatives of the genus Ephestia
comprising the
application of imidacioprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 128: A method of controlling representatives of the genus Heiiothis of
imidacloprid to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the iines C.1 to C.108 of table C.

Table 129: A method of controlling Hellula undalis comprising the application
of imidacloprid
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 130: A method of controlling Ke'rferia lycopersicella comprising the
apptication of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 131: A method of controlling Leucoptera scitella comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.


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Table 132: A method of controlling representatives of the genus Lithocollethis
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 133: A method of controlling Lobesia botrana comprising the application
of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protectec! against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 134: A method of controlling Ostrinia nubiialis comprising
the.application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 135: A method of controlling representatives of the genus Pandemis
comprising the
application of imidactoprid to a herbicidalty resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic piant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 136: A method of controlling Pectinophora gossypiella comprising the
application of
imidacloprid to a herbicidatiy resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 137: A method of controlling Phyliocnistis citrella comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 138: A method of controlling representatives of the genus Pieris
comprising the
application of irnidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 139: A method of controlling Plutella xylostella comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the


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active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 140: A method of controlling representatives of the genus Scirpophaga
comprising
the application of imidacioprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 141: A method of controlling representatives of the genus Sesamia
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 142: A method of controlling representatives of the genus Sparganothis
comprising
the application of imidacloprid to a hs t:ddally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 143: A method of controlling representatives of the genus Spodoptera
comprising the
application of imidacioprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 144: A method of controlling representatives of the genus Tortrix
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 145: A method of controlling Trichoplusia ni comprising the application
of imidacloprid
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 146: A method of controlling representatives of the genus Agriotes
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.1 08 of
table C.


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Table 147: A method of controlling Anthonomus grandis comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 148: A method of controlling representatives of the genus Curculio
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combiridtion of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 149: A method of controlling Diabrotica balteata comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 150: A method of controlling representatives of the genus Leptinotarsa
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 151: A method of controlling representatives of the genus Lissorhoptrus
comprising
the application of imidactoprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 152: A method of controlling representatives of the genus Otiorhynchus
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 153: A method of controlling representatives of the genus Aleurothrixus
comprising
the application of imidacfoprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 154: A method of controlling representatives of the genus Aleyrodes
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principie expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

T I 155: A method of controlling representatives of the genus Aonidielia
comprising the
application of imidacfoprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 156: A method of controlling representatives of the family Aphididae
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 157: A method of controlling representatives of the genus Aphis
comprising the
application of imidaClorrid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 158: A method of controlling Bemisia tabaci comprising the applica4on of
imidacloprid
to a herbicidally resistant transgenic crop, wherein the combination of the
active principie
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 159: A method of controlling representatives of the genus Empoasca
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 160: A method of controlling representatives of the genus Mycus
comprising the
appiication of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 161: A method of controlling representatives of the genus Nephotettix
comprising the
application of imidacioprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the iines C.1 to C.108 of
table C.


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T I 162: A method of controlling representatives of the genus Nitaparvata
comprising the
application of imidactoprid to a herbicidatly resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 163: A method of controlling representatives of the genus Pseudococcus
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the acuve pr~ncipte expressed by the t.ansgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 164: A method of controlling representatives of the genus Psylla
comprising the
application of imidactoprid to a herbicidally resistant trensgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 165: A method of controlling representatives of the genus
Quadraspidiotus
comprising the application of imidacloprid to a herbicidally resistant
transgenic crop, wherein
the combination of the active principle expressed by the transgenic plant and
the crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
tabte C.

Table 166: A method of controlling representatives of the genus Schizaphis
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 167: A method of controlling representatives of the genus Trialeurodes
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 168: A method of controlling representatives of the genus Lyriomyza
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 169: A method of controlling representatives of the genus Oscinelia
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the


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combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

aZ ble 170: A method of controlling representatives of the genus Phorbia
comprising the
application of imidadoprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 171: A method of controlling representatives of the genus Franklinielia
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.

Table 172: A method of controlling representatives of the genus Thrips
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 173: A method of controlling Scirtothrips aurantii comprising the
application of
imidacloprid to a herbicidally resistant transgenic crop, wherein the
combination of the
active principle expressed by the transgenic plant and the crop to be
protected against the
pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 174: A method of controlling representatives of the genus Aceria
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 175: A method of controlling representatives of the genus Aculus
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 176: A method of controliing representatives of the genus Brevipalpus
comprising the
application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.


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T bl~ e 177: A method of controlling representatives of the genus Panonychus
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
jgbig 178: A method of controlling representatives of the genus Phyllocoptruta
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenf:, plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 179: A method of controlling representatives of the genus Tetranychus
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
tabie C.
Table 180: A method of controiling representatives of the genus Heterodera
comprising the
application of imidacloprid to a herbicidaliy resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic piant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 181: A method of controlling representatives of the genus Meloidogyne
comprising
the application of imidacloprid to a herbicidally resistant transgenic crop,
wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
Table 182: A method of controlling representatives of the genus Adoxophyes
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 183: A method of controlling representatives of the genus Agrotis
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 184: A method of controlling Alabama argillaceae comprising the
application of Ti-435
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle


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expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.i to C.108 of table C.

Table 185: A method of controlling Anticarsia gemmatalis comprising the
application of Ti-
435 to a herbicidally resistant transgenic crop, wherein the combination of
the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to anyone of the lines C.1 to C.108 of table C.

Table 186: A method of controlling representatives of the genus Chilo
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 187: A method of controlling Clysia ambiguelia comprising the
application of Ti-435 to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 188: A method of controlling Crocidolomia binotalis comprising the
application of Ti-
435 to a herbicidally resistant transgenic crop, wherein the combination of
the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to anyone of the lines C.1 to C.108 of table C.

Table 189: A method of controlling representatives of the genus Cydia
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principie expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 190: A method of controlling Diparopsis castanea comprising the
application of Ti-435
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 191: A method of controlling representatives of the genus Earias
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.


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T bl : A method of controlling representatives of the genus Ephestia
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop,. wherein
the combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 193: A method of controlling representatives of the genus Heliothis of
Ti-435 to a
herbicidally resistant transgenic crop, wherein the combination of the active
principle
expressed by the transgenic plant aiid the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 194: A method of controlling Hellula undalis comprising the application
of Ti-435 to a
herbicidally resistant transgenic crop, wherein the combination of the active
principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 195: A method of controliing neiferia iycopersicella comprising the
application of Ti-
435 to a herbicidally resistant transgenic crop, wherein the combination of
the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to anyone of the lines C.1 to C.108 of table C.

Table 196: A method of controlling Leucoptera scitella comprising the
application of Ti-435
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the iines C.1 to C.108 of table C.

Table 197: A method of controlling representatives of the genus Lithocollethis
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 198: A method of controlling Lobesia botrana comprising the application
of TI-435 to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 199: A method of controlling Ostrinia nubilalis comprising the
application of Ti-435 to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle


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expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the iines C.1 to C.108 of table C.

Table 200: A method of controlling representatives of the genus Pandemis
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the iines C.1 to C.108 of table C.

Table 201: A method of controlling PecKinophora gossypiella comprising the
application of
Ti-435 to a herbicidally resistant transgenic crop, wherein the combination of
the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to anyone of the lines C.1 to C.108 of table C.

Table 202: A method of controlling Phyllocnistis citrelia comprising the
application of Ti-435
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 203: A method of controlling representatives of the genus Pieris
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 204: A method of controiling Plutella xylostella comprising the
application of Ti-435 to
a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 205: A method of controiling representatives of the genus Scirpophaga
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 206: A method of controlling representatives of the genus Sesamia
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.


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Table 207: A method of controlling representatives of the genus Sparganothis
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 208: A method of controtiing representatives of the genus Spodoptera
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 209: A method of controlling representatives of the genus Tortrix
comprising the
appiication of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principte expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 210: A method of controlling Trichoplusia ni comprising the application
of Ti-435 to a
herbicidally resistant transgenic crop, wherein the combination of the active
principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Table 211: A method of controlling representatives of the genus Agriotes
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 212: A method of controlling Anthonomus grandis comprising the
application of Ti-
435 to a herbicidally resistant transgenic crop, wherein the combination of
the active
principle expressed by the transgenic plant and the crop to be protected
against the pest
correspond to anyone of the lines C.1 to C.108 of table C.

Table 213: A method of controlling representatives of the genus Curculio
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 214: A method of controlling Diabrotica balteata comprising the
application of Ti-435
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle


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expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the dnes C.1 to C.108 of table C.

Table 215: A method of controlling representatives of the genus Leptinotan3a
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transDenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 216: A method of controlling representatives of the genus Lissorhoptrus
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principie expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 217: A method of controlling representatives of the genus Otiorhymchus
comprising
the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein
the combination
of the active principie expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 218: A method of controlling representatives of the genus Aieurothrixus
comprising
the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 219: A method of controlling representatives of the genus Aleyrodes
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to
be.protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 220: A method of controlling representatives of the genus Aonidieiia
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principie expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 221: A method of controlling representatives of the family Aphididae
comprising the
application of Ti-435 to a herbicidaify resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.


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ja~e 222: A method of oontrotiing representatives of the genus Aphis
comprising the
application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 223: A method of controlling 8emisia tabaci oomprising the application
of Ti-435 to a
herbicidally resistant transgenic crop, wherein the combination of the activve
principle
expressed by the transgenlc plant and the crop to be protected against the
pest corresponM
to anyone of the lines C.1 to C.108 of table C.

Table 224: A method of controlling representatives of the genus Empoasca
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 225: A method of controlling representatives of the genus Mycus
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 226: A method of controlling representatives of the genus Nephotettix
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 227: A method of controlling representatives of the genus Nilaparvata
comprising the
application of 1-1-435 to a herbicidally resistant transgenic crop, wherein
the combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 228: A method of controlling representatives of the genus Pseudococcus
comprising
the application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 229: A method of controiiing representatives of the genus Psylla
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of


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the active principie expressed by the transgenic piant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 230: A method of controlling representatives of the genus
Quadraspidiotus
comprising the application of Ti-435 to a herbicidally resistant transgenic
crop, wherein the
combination of the active principle expressed by the transgenic plant and the
crop to be
protected against the pest correspond to anyone of the lines C.1 to C.108 of
table C.
TAbie 231: A method of controiiing representatives of the genus Schizaphis
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principie expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Tabie 232: A method of controlling representatives of the genus Triaieurodes
comprising
the application of Ti-435 to a herbicida0y resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 233: A method of controiiing representatives of the genus Lyriomyza
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principie expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the fines C.1 to C.108 of table C.

Table 234: A method of controlling representatives of the genus Oscineiia
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 235: A method of controlling representatives of the genus Phorbia
comprising the
application of Ti-435 to a herbicidaUy resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 236: A method of controliing representatives of the genus Frankiinieiia
comprising the
application of Ti-435 to a herbicidaiiy resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.


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Table 237: A method of controlling representatives of the genus Thrips
comprising the
application of Ti-435 to a herbicidaily resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

bi~ e 238: A method of controlling Scirtothrips aurantii comprising the
appkation of Ti-435:
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

T I 9 A method of controAing representatives of the genus Aceria comprising
the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 240: A method of controlling representatives of the genus Aculus
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 241: A method of controlling representatives of the genus Brevipaipus
comprising the
application of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 242: A method of controlling representatives of the genus Panonychus
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop,
wrherein the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Tablg 243: A method of controlling representatives of the genus Phyiiocoptruta
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

T I 244: A method of controlling representatives of the genus Tetranychus
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination


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of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

jAbie 245: A method of controlling representatives of the genus Heterodera
comprising the
apptication of Ti-435 to a herbicidally resistant transgenic crop, wherein the
combination of
the active principle expressed by the transgenic plant and the crop to be
protected against
the pest correspond to anyone of the lines C.1 to C.108 of table C.

Table 246: A method of controlling representatives of the genus AAeloidogyne
comprising
the application of Ti-435 to a herbicidally resistant transgenic crop, wherein
the combination
of the active principle expressed by the transgenic plant and the crop to be
protected
against the pest correspond to anyone of the lines C.1 to C.108 of table C.

Tablg247: A method of controlling Mamestra brassica comprising the application
of Ti-435
to a herbicidally resistant transgenic crop, wherein the combination of the
active principle
expressed by the transgenic plant and the crop to be protected against the
pest correspond
to anyone of the lines C.1 to C.108 of table C.

Examnle 131; Action against Anthonomus ar~ndis aduns. SpodQotera littoralis or
Heliothis
ylrescens
Young transgenic cotton plants which express the 8-endotoxin Cry111A are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of
imidacloprid
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising imidacloprid
and con-
ventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1
ppm respectively.
In this test, the control of the tested insects in the transgenic plant is
superior to the control
on the non-transgenic plant.

Examgle B2: Action against AnthQnornus arandis adults. Snodootera littoralis
or Heligthis
virescens


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Young transgenic cotton plants which express the S-eridotoxin CryIIIA are
sprayed wfth an
aqueous emuision spray mixture comprising 100, 50,10, 5, 1 ppm of thiamethoxam
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
aduft Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead bestlas and
luliQ
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising thiamethoxam
and con-
ventional CryI11A-toxin at a concentration of in each case 100, 50, 10, 5, 1
ppm respectively.
In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Example 133: Action aaginst Anthonomus qrandis adults. S22dO2tera littoralis
or Heliothis
virescens
Young transgenic cotton plants which express the 8-endotoxin Cryi11A are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of Ti-435
respectively.
After the spray coating has dried on, the cotton plants are populated with 10
adult
Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens
larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising Ti-435 and
conven-
tional CryIIIA-toxin at a concentration of in each case 100, 50, 10, S. 1 ppm
respecaveiy.
In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Examnle 84: Action against Anthonomus grandis aduits. Scodoutera Cittoraiis or
Heliothis
viresF_ea
Young transgenic cotton plants which express the S-endotoxin Cryla(c) are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50, 10, 5, 1 ppm of Ti-435
respectively.
After the spray coating has dried on, the cotton plants are populated with 10
adult
Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis virescens
larvae


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respectively and introduced into a piastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction In
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising TI-435 and
conven-
tional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1 ppm
respectiveiy.
In this test, the contnoi of the tested insects in the transgenic plant Is
superior, while It is
insufficient in the non transgenic plant.

Examole J~5.~ Action against Anthonomus cmndis adults. SR0ootera littoraiis or
Heliothis
virescens
Young transgenic cotton plants which express the S-endotoxin Cryla(c) are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50,10, 5, 1 ppm of thiamethoxam
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
adult Anthonomus grandis, 10 SNcdQQtera Ifttoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in poputation, or the penrentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants
which have been treated with an emulsion spray mixture comprising thiamethoxam
and con-
ventional CryIIIA-toxin at a concentration of in each case 100, 50, 10, 5, 1
ppm respectively.
In this test, the control of the tested insects in the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

xamoie B6: Action aaaipst Anthonomus grandis adults. Soodoutera littoraiis or
Heiiothis
virescens
Young transgenic cotton plants which express the S-endotoxin Cryla(c) are
sprayed with an
aqueous emulsion spray mixture comprising 100, 50,10, 5,1 ppm of imidacloprid
respectively. After the spray coating has dried on, the cotton plants are
populated with 10
adult Anthonomus grandis, 10 Spodoptera littoralis larvae or 10 Heliothis
virescens larvae
respectively and introduced into a plastic container. Evaluation takes place 3
to 10 days
later. The percentage reduction in population, or the percentage reduction in
feeding
damage (% action), is determined by comparing the number of dead beetles and
the
feeding damage on the transgenic cotton plants with that of non-transgenic
cotton plants


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which have been treated with an emulsion spray mbcture oomprising imidadoprid
conven-
tional CryillA-toxin at a ooncentration of In each case 100, 50, 10, 5, 1 ppm
respectivveiy.
In this test, the control of the tested 'msects In the transgenic plant is
superior, while it is
insufficient in the non-transgenic plant.

Examole B7: Action aaainst Ostrinia nublialls. SDodoDtera snD. or Hetiothis
aoD.

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the
same size
which is planted with conventional maize, both showing natural Infestation
with Qstrin
nubiialis. SDodootera sDD, or Heiiothis, are sprayed with an aqueous emuision
spray mixture
comprising 200, 100, 50, 10, 5, 1 ppm of Ti-435. Immediately afterwards, piot
(b) is treated
with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm of the
endotoxin
expressed by KnockOut . Evaluation takes place 6 days later. The percentage
reduction in
popuiation (% action) is determined by comparing the number of dead pests on
the plants
of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubitaiis. $podoDtArB sflD. or Heiiothis is
observed on the
plants of plot (a), while plot (b) shows a controi level of not over 60%.

Examole B8: Action against Ostrinja nubiiaiis. SDodoDtera SDD. or Hetiothis
sDD.

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the
same size
which is planted with conventional maize, both showing naturai infestation
with Ostrinia
nubiiaiis. SDodogtera sDD. or Heliothis, are sprayed with an aqueous emuision
spray mixture
comprising 200, 100, 50, 10, 5, 1 ppm of thiamethoxam. Immediately afterwards,
plot (b) is
treated with an emulsion spray mixture comprising 200, 100, 50, 10, 5, 1 ppm
of the
endotoxin expressed by KnockOut . Evaluation takes piace 6 days later. The
percentage
reduction in population (% action) is determined by comparing the number of
dead pests on
the piants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubiiai is. SDodoDtera sRD, or Heliothis Is
observed on the
plants of plot (a), while plot (b) shows a control level of not over 60%.

Examole B9: Action against Ostrinia nubiiaiis. SDodoDtera S(,D, or Heiiothis
sDD.

A plot (a) planted with maize cv. KnockOut and an adjacent plot (b) of the
same size
which is planted with conventional maize, both showing natural infestation
with Ostrinia
nubiiaiis. ySDodoj2tera sQD. or Heliothis, are sprayed with an aqueous
emulsion spray mixture


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comprising 200, 100, 50,10, 5, 1 ppm of imidadoprid. Immediately afterwards,
plot (b) is
treated with an emulsion spray mixture comprising 200,100, 50, 10, 5, 1 ppm of
the
endotoxin expressed by KnodcOut . Evaluation takes place 6 days later. The
percentage
reduction in population (% action) is determined by comparing the number of
dead pests on
the plants of plot (a) with that on the plants of plot (b).

Improved control of Ostrinia nubilalis. SDodontera sDD. or Heliothis spp. is
observed on the
plants of plot (a), while plot (b) snows a control level of not over 60%.

Examole B10: Action against Diabrotica baiteata

A plot (a) planted with maize seedlings cv. KnodcOut and an adjacent plot (b)
of the same
size which is planted with conventional maize are sprayed with an aqueous
emulsion of a
spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot
(b) is treated
with an emulsion spray mixture comprising 400 ppm of the endotoxin expressed
by
KnockOut . After the spray coating has dried on, the seedlings are populated
with 10
Diabrotica balteata larvae in the second stage and transferred to a plastic
container. The
test is evaluated 6 days later. The percentage reduction in population (%
action) is deter-
mined by comparing the number of dead pests on the plants of plot (a) with
that on the
plants of plot (b).

Improved control of Diabrotica balteata is observed on the plants of plot (a),
while plot (b)
shows a control level of not over 60%.

Exam lr~ e B11: Action aaainst Aehis gossvnii

Cotton seedlings on a plot (a) expressing the S-endotoxin Cryllia on a plot
(a) and conven-
tional cotton seediings on a plot (b) are infected with Aphis gossypi and
subsequentiy
sprayed with a spray mixture comprising 400 ppm thiamethoxam. immediately
afterwards,
plot (b) is treated with an emulsion spray mixture comprising 400 ppm of the S-
endotoxin
Crylila. The seedlings of plot (a) and (b) are then incubated at 20 C. The
test is evaluated
after 3 and 6 days.

The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of
Aphis gossypi is observed on the plants of plot (a), while plot (b) shows a
control level of not
over 60%.


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Examgle B12: Action aaainst Frankiniella occidentaiis

Cotton seedlings expressing the S-endotoxin Cryilia on a plot (a) and
conventional cotton
seedlings on a plot (b) are infected with Franklinielia occidentaiis and
subsequently sprayed
with a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards,
plot (b) is
treated with an emulsion spray mixture compriWng 400 ppm of the S-endotoxin
Cryllla. The
seedlings of plot (a) and (b) are then incubated at 20 C. The test is
evaluated after 3 and 6
days.

The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of
Franklinieila occidentalis is observed on the plants of plot (a), while plot
(b) shows a control
level of not over 60%.

Example B13: Action aqainst ghis gossy~ii

Cotton seedlings expressing the S-endotoxin CrylA(c) on a plot (a) and
conventional cotton
seedlings on a plot (b) are infected with Aphis gossypii and subsequently
sprayed with a
spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot
(b) is treated
with an emulsion spray mixture comprising 400 ppm of the S-endotoxin Crylila.
The
seedlings of plot (a) and (b) are then incubated at 20 C. The test is
evaluated after 3 and 6
days.

The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of
Aphis goss ii is observed on the plants of plot (a), while plot (b) shows a
control level of
not over 60%.

Examole B14: Action aoainst Franklinielia occidentalis

Cotton seedlings expressing the 8-endotoxin Cryla(c) on a plot (a) and
conventional cotton
seedlings on a plot (b) are infected with Frankliniella occidentalis and
subsequently sprayed
with a spray mixture comprising 400 ppm thiamethoxam. Immediately afterwards,
plot (b) is
treated with an emulsion spray mixture comprising 400 ppm of the 8-endotoxin
Cryla(c). The
seedlings of plot (a) and (b) are then incubated at 20 C. The test is
evaluated after 3 and 6
days.

The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of plot (a) with that on the plants of plot (b).
improved control of


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Franldiniella occidentalis is observed on the piants of plot (a), while plot
(b) shows a control
level of not over 60%.

amcle B15: Action against Neohotettix cincticens

Rice plants on a plot (a) expressing the S-endotoxin CrylA(b) and conventional
rice plants
on a plot (b) are sprayed with a spray mixture comprising 400 ppm
thiamethoxam.
Immediately afterwards, plot (b) is treated wfth an emulsion spray mbcture
comprising
400 ppm of the S-endotoxin CrylA(b). After the spray coating has dried on, the
plants are
infected with Nephotettix cincticeps of the 2nd and 3rd stages. The seedlings
of plot (a) and
(b) are then incubated at 20 C. The test is evaluated after 21 days.

The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of plot (a' with that on the plants of plot (b).
Improved control of
Nephotettix cincticeos is observed on the plants of plot (a), while plot (b)
shows a control
level of not over 60%.

Examrale B16: Action aaainst Nenhotettix cincticeps (systemic)

Rice plants expressing the 8-endotoxin Cryla(b) are planted in a in pot (A)
and conventional
ice plants are planted in a pot (B). Pot (A) is placed in an aqueous emulsion
containing 400
ppm thiamethoxam, whereas plot (B) is placed in a pot containing 400 ppm
thiamethoxam
and 400 ppm of the 8-endotoxin Cryl(b). The plants are subsequently infected
with
Nephotettix cincticeps larvae of the second and third stage. The test is
evaluated after 6
days.

The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of pot (A) with that on the plants of pot (B).
Improved control of
Neohotettix cincticeQs is observed on the plants of pot (A), while pot (B)
shows a control
level of not over 60%.

Examole B17: Action aaainst Nitapanrata lucens

Rice plants on a plot (a) expressing the S-endotoxin CryIA(b) and conventional
rice plants
on a plot (b) are infected with Nilaparvata lugens, subsequently sprayed with
a spray
mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is
treated with
an emulsion spray mixture comprising 400 ppm of the 8-endotoxin CryIA(b). The
seedlings
of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 21
days.


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The percentage reduction in population (% action) Is determined by comparing
the number
of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of
Niiaoarvata luaiens is observed on the plants of plot (a), while plot (b)
shows a control level
of not over 60%.

Examcie 818: Action against Nilananrata fuaens [svatemic)

Rice plants expressing the S-endotoxin CryIA(b) are planted in a in pot (A)
and conventional
rice plants are planted in a pot (B). Pot (A) is placed In an aqueous emulsion
containing 400
ppm thiamethoxam, whereas plot (B) is place in a pot copntaining 400 ppm
thiamethoxam
and 400 ppm of the 8-endotoxin CryIA(b). The plants are subsequently infected
with
Nilaoarvata luaens larvae of the second and third stage. The test is evaluated
after 6 days.
The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of pot (A) with that on the plants of pot (B).
Improved control of
Nephotettix cincticeps is observed on the plants of pot (A), while pot (B)
shows a control
level of not over 60%.

Examnle B19: Action against Neohotettix cincticegs

Rice plants on a plot (a) expressing the S-endotoxin CrylA(c) and conventional
rice plants
on a plot (b) are sprayed with a spray mixture comprising 400 ppm
thiamethoxam.
Immediately afterwards, plot (b) is treated with an emulsion spray mixture
comprising
400 ppm of the 8-endotoxin CrylA(c). After the spray coating has dried on, the
plants are
infected with Nephotettix cincticeps of the 2nd and 3rd stages. The seedlings
of plot (a) and
(b) are then incubated at 20 C. The test is evaluated after 21 days.

The percentage reduction in popuiation (% acfion) is determined by comparing
the number
of dead pests on the plants of piot (a) with that on the plants of plot (b).
Improved control of
Nenhotettix cincticecs is observed on the plants of plot (a), while plot (b)
shows a control
level of not over 60%.

Examale B20: Action against Nedhotettix cinctice2s (s emic)

Rice plants expressing the S-endotoxin Cryla(c) are planted in a in pot (A)
and conventional
ice plants are planted in a pot (B). Pot (A) is placed in an aqueous emulsion
containing 400
ppm thiamethoxam, whereas plot (B) is placed in a pot containing 400 ppm
thiamethoxam
and 400 ppm of the 8-endotoxin Cryi(c). The plants are subsequently infected
with


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Nephotettix cincticeps larvae of the second and third stage. The test is
evaluated after 6
days.

The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of pot (A) with that on the plants of pot (B).
improved control of
Nephotettix cincticens is observed on the plants of pot (A), while pot (B)
shows a control
level of not over 60%.

Exampie B21: Action aaainst Niiaoarvata lug2

Rice plants on a plot (a) expressing the S-endotoxin CrylA(c) and conventional
rice plants
on a plot (b) are infected with NiiaRarvata lugens, subsequently sprayed with
a spray
mixture comprising 400 ppm thiamethoxam. Immediately afterwards, plot (b) is
treated with
an emulsion spray mixture comprising 400 ppm of the 8-endotoxin CrylA(c). The
seedlings
of plot (a) and (b) are then incubated at 20 C. The test is evaluated after 21
days.

The percentage reduction in population (% acctieon) is determined by comparing
the number
of dead pests on the plants of plot (a) with that on the plants of plot (b).
Improved control of
Nilaparvata lugens is observed on the plants of plot (a), while plot (b) shows
a control level
of not over 0%.

Exampie B22: Action against Niiacarvata iuaens la tys emicl

Rice plants expressing the S-endotoxin CrylA(c) are planted in a in pot (A)
and conventional
rice plants are planted in a pot (B). Pot (A) is placed in an aqueous emulsion
containing 400
ppm thiamethoxam, whereas plot (B) is place in a pot copntaining 400 ppm
thiamethoxam
and 400 ppm of the S-endotoxin CrylA(c). The plants are subsequently infected
with
Niiagarvata iu4ens larvae of the second and third stage. The test is evaluated
after 6 days.
The percentage reduction in population (% action) is determined by comparing
the number
of dead pests on the plants of pot (A) with that on the plants of pot (B).
Improved control of
Nephotettix cincticecs is observed on the plants of pot (A), while pot (B)
shows a controi
level of not over, 60 %.

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Administrative Status

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Administrative Status

Title Date
Forecasted Issue Date 2008-06-10
(86) PCT Filing Date 1999-01-14
(87) PCT Publication Date 1999-07-22
(85) National Entry 2000-06-27
Examination Requested 2004-01-14
(45) Issued 2008-06-10
Expired 2019-01-14

Abandonment History

Abandonment Date Reason Reinstatement Date
2006-12-19 R30(2) - Failure to Respond 2007-01-31

Payment History

Fee Type Anniversary Year Due Date Amount Paid Paid Date
Application Fee $300.00 2000-06-27
Registration of a document - section 124 $100.00 2000-08-16
Maintenance Fee - Application - New Act 2 2001-01-15 $100.00 2000-12-27
Maintenance Fee - Application - New Act 3 2002-01-14 $100.00 2001-11-26
Registration of a document - section 124 $50.00 2002-11-05
Maintenance Fee - Application - New Act 4 2003-01-14 $100.00 2003-01-06
Maintenance Fee - Application - New Act 5 2004-01-14 $150.00 2003-12-22
Request for Examination $800.00 2004-01-14
Maintenance Fee - Application - New Act 6 2005-01-14 $200.00 2005-01-06
Maintenance Fee - Application - New Act 7 2006-01-16 $200.00 2006-01-04
Maintenance Fee - Application - New Act 8 2007-01-15 $200.00 2006-12-05
Reinstatement - failure to respond to examiners report $200.00 2007-01-31
Maintenance Fee - Application - New Act 9 2008-01-14 $200.00 2007-12-05
Final Fee $480.00 2008-03-19
Maintenance Fee - Patent - New Act 10 2009-01-14 $250.00 2008-12-15
Maintenance Fee - Patent - New Act 11 2010-01-14 $250.00 2009-12-16
Maintenance Fee - Patent - New Act 12 2011-01-14 $250.00 2010-12-17
Maintenance Fee - Patent - New Act 13 2012-01-16 $250.00 2012-01-05
Maintenance Fee - Patent - New Act 14 2013-01-14 $250.00 2012-12-20
Maintenance Fee - Patent - New Act 15 2014-01-14 $450.00 2013-12-19
Maintenance Fee - Patent - New Act 16 2015-01-14 $450.00 2014-12-22
Maintenance Fee - Patent - New Act 17 2016-01-14 $450.00 2015-12-17
Maintenance Fee - Patent - New Act 18 2017-01-16 $450.00 2016-12-19
Maintenance Fee - Patent - New Act 19 2018-01-15 $450.00 2017-12-15
Owners on Record

Note: Records showing the ownership history in alphabetical order.

Current Owners on Record
SYNGENTA PARTICIPATIONS AG
Past Owners on Record
BUHOLZER, HUBERT
LEE, BRUCE
NOVARTIS AG
SUTTER, MARIUS
Past Owners that do not appear in the "Owners on Record" listing will appear in other documentation within the application.
Documents

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Document
Description 
Date
(yyyy-mm-dd) 
Number of pages   Size of Image (KB) 
Abstract 2000-06-27 1 58
Description 2000-06-27 129 6,128
Claims 2000-06-27 1 24
Cover Page 2000-10-05 1 42
Claims 2007-01-31 1 29
Description 2007-01-31 129 6,125
Cover Page 2008-05-12 1 33
Prosecution-Amendment 2004-01-14 1 38
Assignment 2000-06-27 5 173
PCT 2000-06-27 14 601
Assignment 2002-11-05 11 478
Prosecution-Amendment 2006-06-19 3 77
Prosecution-Amendment 2007-01-31 5 197
Correspondence 2008-03-19 1 39