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Patent 2322549 Summary

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(12) Patent Application: (11) CA 2322549
(54) English Title: MEDICINAL PRODUCTS CREATED FROM CANNABIS USING CANNABINOID PROFILES AS INDICATORS OF EFFICACY
(54) French Title: PRODUITS MEDICAUX OBTENUS A PARTIR DU CHANVRE EN UTILISANT DES PROFILES DE CANNABINOIDES COMME INDICATEURS D'EFFICACITE
Status: Dead
Bibliographic Data
(51) International Patent Classification (IPC):
  • A01H 5/00 (2006.01)
  • A01H 3/02 (2006.01)
  • A01H 3/04 (2006.01)
  • A01H 5/12 (2006.01)
  • C12N 5/14 (2006.01)
  • C12N 15/82 (2006.01)
(72) Inventors :
  • HORNBY, A. PAUL (Canada)
  • SUTHERLAND, MARTIN D. (Canada)
  • DIMOTOFF, PAVEL U. (Canada)
(73) Owners :
  • HORNBY, A. PAUL (Canada)
  • SUTHERLAND, MARTIN D. (Canada)
  • DIMOTOFF, PAVEL U. (Canada)
(71) Applicants :
  • HORNBY, A. PAUL (Canada)
  • SUTHERLAND, MARTIN D. (Canada)
  • DIMOTOFF, PAVEL U. (Canada)
(74) Agent: NA
(74) Associate agent: NA
(45) Issued:
(22) Filed Date: 2000-09-27
(41) Open to Public Inspection: 2002-03-27
Availability of licence: N/A
(25) Language of filing: English

Patent Cooperation Treaty (PCT): No

(30) Application Priority Data: None

Abstracts

English Abstract



A process is described whereby a back-crossing protocol is used to create
cannabis plants
which are further standardized into medicinal products. A specific lighting
regime is first
used to bring a cloned plant to the vegetative stage followed by treatment
with defined
type of Gibberellic Acid (GA3) which stimulates sex reversal; from a female to
a male.
The pollen from this new male is used to pollenate the mother plant with her
own pollen.
This procedure creates a new variety of true breeding plant with a
reproducible genome,
which can be cloned into more plants. Confirmation of reproducibility is
achieved us Gas
Chromatography/ Mass Spectroscopy (GC/MS) to determine the Cannabinoid Profile
of
the pollenated plant. This cannabinoid profile is used as an index for the
type of
medicinal product which can be produced. Once this profile is established the
raw
material is gound into a powder, the cannabinoid profile is re-verified and
the powder can
be used as a medicine for symptom relief from many different ailments such as
epileptic
siezures, glaucoma, nausea/pain, multiple sclerosis tremors, migraine,
fibromyalgia,
hepatitis, depression, anorexia, anxiety. Route of administration of this
powder can be
made either oral or by smoking.


Claims

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Description

Note: Descriptions are shown in the official language in which they were submitted.



CA 02322549 2000-09-27
Cannabis Medicinals Formulation
Back-crossing of a given strain of cannabis is used to create a standardized
medicinal
product as verified by the cannabinoid profile. This medicine can be used for
symptom
relief from many different conditions.
Background of the Invention
The medicinal properties of cannabis have be known for thousands of years.
Chinese
medicine men were prescribing it as a treatment for epileptic seizures in 400
BC.
Much more recently a host of scientific data is establishing the role of
cannabis as an
effective medicine for symptom relief from many different ailments. A method
of
creating a true breeding strain of cannabis is described which can, in turn,
be used to


CA 02322549 2000-09-27
devise a standardized medicinal product. Standardization is based on the
cannabinoid
profile, a group of compounds which can be identified and quantitated by GC/MS
or by
HPLC with a diode array detector. It is these compounds which give cannabis
its
symptom relieving properties. Knowledge of a given cannabinoid profile allows
a
practitioner to determine which ailment the medicine can be applied to. In
addition,
knowledge of the cannabinoid profile allows blending of the powdered cannabis
material
into a product with distinct cannabinoid ratios to illicit a standardized
product.
Objectives of the Invention
It is an objective of this invention to produce cannabis clones with defined
cannabinoid
profiles which can be used as a medicine.
A further objective of this invention is to establish a standard operating
procedure of
back-crossing to produce a new variety of cannabis plants which can be used as
a raw
material for producing a medicine.
A further objective of this invention to use cannabinoid profiles determined
by Gas
Chromatography or by HPLC as an indicator to medicinal properties.
A further objective of this invention is to standardize the product using a
back-crossing
technique to produce standardized true breeding plants with defined
cannabinoid profiles.
A further objective of this invention is to produce a standardized cannabis
powder which
can be blended with other standardized cannabis powders to make a product
containing
known amounts of specific cannabinoids.
A further objective of this invention is to establish standard operating
procedures
whereby reproducible medicinal products can be fabricated from cannabis.
Summary of the Invention
According to the present invention a process is described whereby new
varieties of
cannabis plants can be created which are true breeding. These true breeding
plants are
standardized to contain known amounts of specific cannabinoid compounds which
allow
symptom relief from many different ailments. These products are standardized
based on
their cannabinoid profiles.

Representative Drawing

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Administrative Status

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Administrative Status

Title Date
Forecasted Issue Date Unavailable
(22) Filed 2000-09-27
(41) Open to Public Inspection 2002-03-27
Dead Application 2003-05-12

Abandonment History

Abandonment Date Reason Reinstatement Date
2002-05-13 FAILURE TO COMPLETE
2002-09-27 FAILURE TO PAY APPLICATION MAINTENANCE FEE

Payment History

Fee Type Anniversary Year Due Date Amount Paid Paid Date
Application Fee $150.00 2000-09-27
Owners on Record

Note: Records showing the ownership history in alphabetical order.

Current Owners on Record
HORNBY, A. PAUL
SUTHERLAND, MARTIN D.
DIMOTOFF, PAVEL U.
Past Owners on Record
None
Past Owners that do not appear in the "Owners on Record" listing will appear in other documentation within the application.
Documents

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Document
Description 
Date
(yyyy-mm-dd) 
Number of pages   Size of Image (KB) 
Abstract 2000-09-27 1 31
Description 2000-09-27 2 71
Cover Page 2002-04-02 1 42
Correspondence 2000-11-16 1 2
Assignment 2000-09-27 3 101
Correspondence 2000-09-27 1 60
Correspondence 2001-12-17 1 28
Correspondence 2001-12-21 1 16
Correspondence 2001-12-13 1 18
Correspondence 2002-02-12 1 20