Note: Descriptions are shown in the official language in which they were submitted.
CA 02392544 2002-07-04
11TLE: Natural therapeutic composition for the treatrnent of wounds and sores
This invention relates to a therapeutic composition for the treatment of
wounds, sores,
and diseases.
Studies have shown that Vitamin A plays a role in the maintenance of skin;
that Vitamin C
helps fight infections, promotes the healing of cuts, abrasions and "rounds
and is required to
maintain structural and functional integrity of cell walls and small blood
vessels; that Vitamin
E helps prevent oxidation of fatty acids present in the membrane of all cells;
that Evening
Primrose oil has anti-inflammatory and pain relieving effects; that mineral
oil may be used to
cleanse the skin; and that petroleum belly may be used as a carrier for
topical comp~itions.
The prior art relevant to this invention consists of various wound healing and
anti-
inflammatory compositions comprised of one or a few of the above ingredients
and other herbal,
vitamin and chemical mixtures.
CA 02392544 2002-07-04
It is laiown in the art that skin wound healing may be enhanced by the topical
application of
vitamin, herbal and/or chemical compositions to the affected area or through
the ingestion of
some such compositions. However, existing inventions inadequately address the
need for a
therapeutic composition that is all natural, provides fast pain relief,
reduces inflammation
arid enhances the healing of wownds and sores.
United States Patent No. 4,505,896 bo J. E. Bernstein, filed Navtmber 24,
1980, is a topical and
oral method of treating lesions of acne vulgaris. It is comprised of a
therapeutically effective
amount of nicotine acid or nicotinannide. (The Bernstein patent does not claim
use of Vitamin A,
Vitamin C, Vitamin E, Evening Primrose oil, mineral oil nor a petroleum
carrier).
United States Patent No. 5,176,918 to J. L. )ones, filed December 20, 1990, is
a topical
medicament, comprised of a dilute solution of sodium bicarbonate and a
transdermal carrier for
relieving pain from sunburn; minor burns and minor inflammatory diseases. (The
Jones patent
uses a transdetTnal carrier, typically glycerin, but does not claim uiae of
Vitamin A, Vitamin C,
Vitamin E, Evening Primrose oil nor mineral oil).
United States Patent No. 5,240,945 to T. G. Warshaw, filed February 18, 1992,
is a method arid
composition for treating acne comprised of a lower alkyl nicotinate or methyl
rucotinate. (The
Warshaw patent utilizes a topically acceptable and compatible pharmaceutical
carrier, such
as petrolatum, but does not claim use of Vitamin A, Vitamin C, Vitamin E,
Evening Primrose oil
nor mineral oil).
United States Patent No. 3,96b,452 to B. A. Whittle, filed February 28, 1992,
is a
pharmaceutical composition for the treatment of skin disorders comprised of
extracts of herbs to
provide an anti-inflammatory agent, an adrenocortical stimulant and a cortisol
protectnng
agent. The herbs may be chosen hum a group consist;ng of Potentilla
chittensis, Tribulus
terrestris, Akebia trifoliate and select others. The solvent may be chosen
from a group
consisting of chloroform, methylene chloride, acetone, propanol, ethanol,
methanol and select
others. (The Whittle patent claims use of a carrier in form of a silica gel,
but does not claim use
of Vitamin A, Vitamin C, Vitamin EP Evening Primrose oil nor mineral oil).
"Early Clinical Experience with Topical Collagen in Vascular Wa~.wd Care", by
J. Morris et al,
published in 1994 by the Wound, Ostomy and Continetxe Nurses Society,
discusses waa~d
treatment for bilateral venous ulcers, including topical application of soap
and water, hydrogen
peroxide, saline solution and collagen. (The treatment mentioned in the
article does not claim
use of Vitamin A, Vitamin C, Vitamin E, Evening Primrose oil, mineral oil na a
petroleum
carrier).
Canadian Patent No. 2,191,604 (United States Patent no. 5,648,380) to A.
Martin, filed May 22,
1995, laid open January 11, 1996, is a therapeutic anti-inflammatory wwnd
healing
composition comprised of an anti-inflammatory agent and a wound healing
composition. The
wound healing composition is comprised of pyruvate, an antioxidant and a
mixture of saturated
and unsaturated fatty acids. The anti-inflammatory agent may be chosen from a
ge~oup
consisting of etodale, evening primrose oil, salsalate, cortisone, and select
others. The
antioxidant may be chosen from a group conaiatirAg of all forms of Vitamin A,
Vitamin C,
Vitamin E and mixtures thereof. The composition is also earnprised of a
pharmaceutically
acceptable carrier. This may be distinguished from this invention by mineral
oil in the claims.
Canadian Patent No. 2.192,603 (United States Patent No. 5,663,208} to A.
Martin, filed May 22,
1995, laid open February 8,1996, is an anti-fungal wound healing composition
with anti-fungal
agent comprised of lactic and sorbic acid, terconazole or select others.
United States Patent No. 5,652,274 to A. Martin, filed May 22, 1995, is a
therapeutic wound
healing composition and method of preparation. The wood healing composition is
comprised
of pryuvate, an antioxidant and a mixture of saturated and unsaturated fatty
acids. This may
be distinguished from this invention by mineral oil in the claims.
CA 02392544 2002-07-04
United States Patent No. 5,674,912 to A. Martin, filed May 22, 1995, is a sun-
screen wau~d
healing composition and method of preparation. The sumcseen agent may be
selected from a
group consisting of titanium dioxide, urea, oxybenzone and select others.
(All the Martin patents claim use of Vitamin A, Vitamin C, and/or Vitamin E as
an
antioxidant, Evening Primrose oil as an anti-inflammatory agent and a
pharmaceutically
acceptable carrier. However, the Martin patents require that an agent and a
wound healing
rnmposition, that must be comprised of pyruvate, an antioxidant, and a mixture
of saturated
and unsaturated fatty acids, must be used together. The Martin patents do not
claim v,~se of
mineral oil). '
United States Patent No. 5,916,573 to S. M. Spiers et al, filed August 1996,
is a topical
treatment of the skin with, a grape-seed oil comp~ition. The composition is
comprised of
grape-seed oil, a hydrating agent that may be chosen from a group rnnsisting
of Vitamin E oil,
primrose oil and select others, an amino acid and deionized water. (The Spiers
patent does not
claim use of Vitamin A, Vitamin C, nor mineral oil).
United States Patent No. 6,107,349 to P. Mantynen, filed April 16, 1998, is a
method and
composition for treating psoriasis. The method is rnmprised of oral ingestion
by a patient of
Vitamin E, Evening Primrose oil, folic acid and B-complex vitamins. (The
Mantynen patent is
not topical and does not claim use of Vitamin A, Vitamin C, mineral oil nor a
petroleum
carrier).
Canadian Patent No. 2,329,160 to S. Leibovich (United States patent no.
6,187,822), filed in the
United State on June 11, 1998, laid open in Canada on De~nber 16, 1999, is a
wound treatment
through inhibition of adenosine diphosphate ribosyl transferase. The inhibitor
is comprised
from a group consisti~ of Vitamin K1, KZ, K3, K4 and select others. The
rnmposition is further
comprised of a pharmaceutically acceptable carrier. An anti-inflammatory agent
may also be
used that is comprised of Evening Primrose oil. (The Leibovich patent does not
claim use of
Vitamin A, Vitamin~C, Vitamin E nor mineral oil).
United Stated Patent No. 6,203,805 to D. F. Collies et al, filed November 10,
1998, is a topical
composition containing whey proteins, Vitamin A, Vitamin C and Vitamin E to
improve the
resiliency of the skin. (The Collies patent does not claim use of Evening
Primrose oil, mineral
oil nor a petroleum carrier).
German Patent No.19800982 to F. Karl-Heinz, filed January 14, 1999, is an
ointment containing
ethereal oil, liposomes and Vitamins for treating neruodermatitis, psoriasis
and eczema. The
medical ointment base is comprised of ingredients selected from a group
comprised of Vaseline,
beeswax, paraffin or select others. The active ingredient used in conjunction
with the base may
be chosen from a group consisting of vitamins, lfposome and ethereal. (The
Karl-Heinz patent
does not claim use of Evening Primrose oil nor mineral oil).
United Stated Patent No. 6,183,761 to D. L. Bissett, filed March 12, 1999, is
a composition for
regulating skin appearance. The topical composition is comprised of a vitamin
B3 compound, a
polycyclic compound, flavanones, chalcones, isoflavones, coumarins, chromones,
dicomarols,
chromaeols, sterols, selected others and mixtures thereof. (The Bissett patent
does not claim
use of Vitamin A, Vitamin C, Vitamin E, Evening Primrose oil, mineral oil nor
a petroleum
carrier).
Canadian Patent No. 2,285,818 to J. C. Liu et al, filed October 12,1999, laid
open April 13, 2000,
is a composition to enhance skin permeation of topical skin agents. The
composition l s
comprised of an active agent that may be chosen from a grcnip consisting of
hydrophobic and
hydrophilic active agents and a polymeric emu),sifier. The hydrophobic and
hydrophilic
agents may be f~nm a group c~sisting~of ~Vftamin A, Vitamin C, Vitamin E,
wound
CA 02392544 2002-07-04
healing promoters, sunscreens, fragrances, and select others. (The Liu patent
does not claim use
of Evening Primrose oil, mineral oil nor a petroleum~carrier).
United States Patent No. 6,248,763 to R Scivoletto, filed October 12,1999, is
a rnmposition for
treating skin conditions, comprising of methyl nicotinate, aloe vera gel,
Vitamin E, glycerin,
silk amino acids and select others. (The liernstein patent does rat claim use
of Vitamin A,
Vitamin C, Evening Primrose oil,, nor mineral oil).
United States Patent No. 6,187,743 to E. T. Obi-Tabot, filed December 10,
1999, is a composition
and method for enhancing wound healing. The method is comprised of a
composition of bovine
collagen type I and aipha-tocopherol in a mixture which may be combined with
vitamins.
('The Obi-Tabot patent does not claim t~se of Evening Primrose oil, mineral
oil nor a petroleum
carrier).
As disclosed above, a number of wound and disease treating compositions exist
that are topical
and ingested, and are composed of herbs, chemicals, and vitamins. However,
none of the prior
art discloses an invention that utilizes a topically and orally administered
natural therapeutic
composition for the treatment of diseases and wounds comprised of a mixture of
Vitamin A,
Vitamin E, Evening Primrose Oil and Mineral Oil.
CA 02392544 2002-07-04
Summary of the invention
This invention relates to a therapeutic composition for the treatment of
wounds and
diseases that is comprised of natural ingredients.
From personal experience we have discovered the following traits associated
with the
specific components of the invention:
Vitamin A topically applied to the skin, particularly on the face, results in
improved appearance of the skin;
Vitamin C acts like natural Aspiring by combating pain and inflammation. It is
known to help arthritis;
Vitamin E topically applied to scalds results in reduced pain and improved
healing of the wound;
Evenin;~ Primrose Oil topically applied to the face results in a healthier
appearance of the skin. Used on wounds, i.e. after a gall bladder surgery,
applied
daily for six weeks, results in advanced healing of the wound. It may also be
used
to treat chronic fatigue syndrome;
Mineral Oil topically applied to severe sunburn may result in easement of pain
and reduced inflammation of the wound;
Mynah has antiseptic and astringent properties that may reduce inflammation
and infection, thereby promoting healing of healthy tissue;
Olive Oil aids in dry skin problems and helps to clean and heal wounds,
ulcers,
sores, abrasions, and sunburn; and,
Peppermint Extract topically applied, particularly to the head, results in
reduced
pain in, for example, cases of headache, sinus and earache.
Using our knowledge of and experience with the above ingredients, we
experimented
with various quantities of all of the ingredients combined into one
composition, with
several slight variants for specific indications. We discovered that the
ingredients work
well together and complemented and enhanced the restorative and healing
effects of each
other when combined, particularly in the proportions disclosed in the formulae
of the
various embodiments of the invention.
The invention is comprised of four (4) main elements and may be used topically
or
internally:
(a) Vitamin A
(b) Vitamin E
CA 02392544 2002-07-04
(c) Evening Primrose Oil
(d) Mineral Oil
In addition to the elements listed above, small amounts of Vitamin C and other
natural
ingredients such as Olive Oil, Peppermint Extract and Myrrah may be present in
some
embodiments. Additionally, some embodiments may use a suitable Garner, such as
Petroleum Jelly, for topical application. The amount of carrier used can be
varied to
regulate the consistency of the composition. In some indications a thicker
composition is
more desirable.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
The invention, in a first preferred embodiment, is a topical or oral
composition comprised
of the following ingredients in the :Following proportions by volumes:
Vitamin A 0.5 - 2.5
Vitamin E 35 - 45
Evening Primrose Oil 45 - 55
Mineral Oil 4.5 - 6.5
This embodiment of the invention is effective as a therapeutic agent for the
treatment of
bedsores, earache, headache, and ezcema of and around the eye when applied on
or
proximal to the affected areas.
Example : A test of the preferred embodiment of the invention was performed in
February 2001 using the following composition of ingredients:
Vitamin A 0.5
ml
Vitamin E 15 ml
Evening Primrose 20 ml
Oil
Mineral Oil 2.0
ml
The patient was suffering from severe bedsores. We topically applied the
composition of
the preferred embodiment of the invention to the patient's wounds daily with
startling
success. The attending physicians and care workers were also very impressed
with the
results. The patient admitted that th.e pain diminished instantly upon the
application of the
composition that is the preferred embodiment of this invention and after five
days of
daily use, the sores were not painful at all. The inflammation of the wound
greatly
diminished and the wound appeared to be healing from the inside to the
outside, at a rate
much more rapid than normally associated with such sores. We have also tried
the
invention on itches, scalds, cold sores, sore throats, and burns with similar
results.
In a second and further embodiment, the present invention provides a topical
composition
comprised of the same proportions of ingredients as in the first embodiment
above, but
using Petroleum Jelly as a carrier.
6
CA 02392544 2002-07-04
We have used the second embodiment in the successful treatment of psoriasis,
body itch,
insect bites, burns and scalds, and dry skin on the hands and face when it was
applied on
or proximal to the affected areas.
In a third and further embodiment, the present invention provides a topical
composition
comprised of the following ingredients in the following proportions by
volumes:
Vitamin A 0.5 - 2.0
Vitamin E 30 - 45
Evening Primrose 45 - 55
Oil
Mineral Oil 4 6
-
Olive Oil 4 6
-
in a suitable as
carrier, such Petroleum
Jelly.
We have used the third embodiment in the successful treatment of psoriasis,
body itch,
insect bites, dry skin on the face and hands, burns and scalds by applying it
on or
proximal to the affected areas. In one example of the third embodiment used
topically for
such treatment the composition had the following ingredients:
Vitamin A 0.5
ml
Vitamin E 15 ml
Evening Primrose 20 ml
Oil
Mineral Oil 2.0
ml
Olive Oil 2.0
rnl
In a fourth and further embodiment, the present invention provides a topical
composition
comprised of the following ingredients in the following proportions by
volumes:
Vitamin A 0.5 - 2
Vitamin C 2 3.5
-
Vitamin E 30 - 40
Evening Primrose 45 - .SS
Oil
Mineral Oil 3.5 - 6.5
Myrrah 0.5 - 1.5
Olive Oil 3.5 - 6.5
in a suitable carrier, such as Petroleum Jelly.
We have used the fourth embodiment in the successful treatment of some types
of
psoriasis and some types of ezcema by applying it on or proximal to the
affected area. In
one example of the fourth embodiment used topically for such treatment the
composition
had the following ingredients:
7
CA 02392544 2002-07-04
Vitamin A 0.5
ml
Vitamin C 1.0
ml
Vitamin E 15 rr~l
Evening Primrose 20 ml
Oil
Mineral Oil 2.0
ml
Myrrah 0.4
rnl
Olive Oil 2.0
ml
In a fifth and further embodiment, the present invention provides a topical or
oral
composition comprised of the following ingredients in the following
proportions by
volumes:
Vitamin A 0.5 - 2
Vitamin C 2 - 3.5
Vitamin E 30 - 40
Evening Primrose 45 - 55
Oil
Mineral Oil 3.5 - 6.5
Myrrah 0.5 - 1.5
Olive Oil 3.5 - b.5
Peppermint Extract0.5 - 1.5
in a suitable carrier, such as Petroleum Jelly, for topical applications.
We have used the fifth embodiment in the successful treatment of headaches and
migraine. In one example of the fifth embodiment used topically by applying it
on or
proximal to the affected areas fox such treatment, the composition had the
following
ingredients:
Vitamin A 0.5
ml
Vitamin C 1.0
ml
Vitamin E 15 ml
Evening Primrose 20 ml
Oil
Mineral Oil 2.0
ml
Myrrah 0.4
ml
Olive Oil 2.0
ml
Peppermint Extract0.4
rnl
As demonstrated, the invention provides a new and effective therapeutic
composition
comprised of all natural ingredients, for the treatment of wounds, sores and
diseases.
While the invention has been described in detail and with reference to
specific
embodiments thereof, it will be apparent to one skilled in the art that
various changes and
modifications can be made therein without departing from the spirit and scope
thereof.
8
