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(12) Patent: | (11) CA 2575406 |
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(54) English Title: | TREATMENT OF HYPERPROLIFERATIVE DISEASE WITH SUPERANTIGENS IN COMBINATION WITH ANOTHER ANTICANCER AGENT |
(54) French Title: | TRAITEMENT DES MALADIES HYPERPROLIFERANTES A L'AIDE DE SUPER-ANTIGENES COMBINES A UN AUTRE AGENT ANTICANCEREUX |
Status: | Granted |
(51) International Patent Classification (IPC): |
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(72) Inventors : |
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(73) Owners : |
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(71) Applicants : |
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(74) Agent: | GOWLING WLG (CANADA) LLP |
(74) Associate agent: | |
(45) Issued: | 2016-06-21 |
(86) PCT Filing Date: | 2005-08-12 |
(87) Open to Public Inspection: | 2006-02-16 |
Examination requested: | 2010-05-26 |
Availability of licence: | N/A |
(25) Language of filing: | English |
Patent Cooperation Treaty (PCT): | Yes |
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(86) PCT Filing Number: | PCT/EP2005/008815 |
(87) International Publication Number: | WO2006/015882 |
(85) National Entry: | 2007-01-26 |
(30) Application Priority Data: | |||||||||
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The present invention relates to methods of treating mammals affected by, for
example, a hyperproliferative disease such as cancer, by administering a
tumor~ targeted superantigen and a chemotherapeutic agent, whereby the
administration of the tumor-targeted superantigen and chemotherapeutic agent
reduce the antibody re~sponse and enhance the T cell response. The
superantigen, wild-type or modified, is fused to a target-seeking moiety, such
as an antibody or an antibody active fragment. The combined administration of
a superantigen and a chemotherapeutic agent pro~vides enhanced therapeutic
effects in a treated animal.
Cette invention a pour objet des procédés de traitement des mammifères souffrant, par exemple, de maladie hyperproliférante comme le cancer, par administration d~un super-antigène ciblant la tumeur et d~un agent chimiothérapeutique, l~administration de ceux-ci permettant de réduire la réponse des anticorps et de développer la réponse du lymphocyte T. Le super-antigène, de type sauvage ou modifié, est mêlé à un groupe caractéristique de recherche de cible, tel qu~un anticorps ou un fragment actif d~anticorps. L~administration combinée d~un super-antigène et d~un agent chimiothérapeutique a, sur un animal traité, des effets thérapeutiques améliorés.
Note: Claims are shown in the official language in which they were submitted.
Note: Descriptions are shown in the official language in which they were submitted.
Sorry, the representative drawing for patent document number 2575406 was not found.
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Title | Date |
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Forecasted Issue Date | 2016-06-21 |
(86) PCT Filing Date | 2005-08-12 |
(87) PCT Publication Date | 2006-02-16 |
(85) National Entry | 2007-01-26 |
Examination Requested | 2010-05-26 |
(45) Issued | 2016-06-21 |
There is no abandonment history.
Last Payment of $473.65 was received on 2023-07-18
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Description | Date | Amount |
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Next Payment if standard fee | 2024-08-12 | $624.00 |
Next Payment if small entity fee | 2024-08-12 | $253.00 |
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Note: Records showing the ownership history in alphabetical order.
Current Owners on Record |
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ACTIVE BIOTECH AB |
Past Owners on Record |
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FORSBERG, GORAN |
HEDLUND, GUNNAR |
WALLEN-OHMAN, MARIE |
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