Note: Descriptions are shown in the official language in which they were submitted.
I ~, G
CA 02162877 2002-11-29
TITLE: MONOHYDRATE DEXTROSE OR GLUCOSE COMPOSITION
Background of the Invention
the present invention relates to a composition for the
treatment of a "hangover" i.e. the after-effects of excessive
consumption of ethyl alcohol by a human being.
summary of the Invention
An object of the invention is the provision of a
composition which can be taken a5 a single treatment (in one
or more doses) to counteract a hangover.
The present invention provides a composition including the
following compounds:
(a) 0 . 596 - 2 . 496 by wei ght ascorbi c aci d;
(b) 0.0001% - 0.4% by weight of a non-toxic potassium
salt;
(c) 0.0001% - 0.4% by weight of a non-toxic magnesium
salt;
(d) 0.001% - 2.5% by weight vitamin B6;
(e) 0 . 000196 - 0 . 079b by wei ght of zi nc oxi de ;
the balance of the Composition being monohydrate dextrose
or glucose.
Detailed Description of the Tnvention
one of the known effects of alcohol in the human system
is to lower the blood sugar, and this leads to an increase in
1
WO 94/27449 PCTINZ94100042
liver activity as the liver increases its normal rate of
breaking down glycogen into blood sugar, to restore the
optimum blood sugar level. Continual or frequent such
increase in liver activity can lead to cirrhosis of the liver.
The brain uses about 25% of available blood sugar, and so
is particularly rapidly effected by a drop in blood sugar
levels:- hence the symptoms of slurred speech, memory lapses,
headaches, loss of co-ordination, blurred vision, personality
changes, and so on commonly associated with alcohol
consumption.
Monohydrate dextrose breaks down to glucose in the body,
and thus both monohydrate dextrose and glucose are quickly and
readily assimilated into the blood stream to boost the blood
sugar level and help prevent liver damage and counteract brain
disfunction.
The presence of alcohol in the system also is believed to
increase the amount and frequency of urine passed, leading to
a depletion of vitamin C, (ascorbic acid), magnesium and
potassium in the system, and these losses need to be replaced
to allow the system to resume functioning correctly. Examples
of suitable magnesium and potassium salts are magnesium
sulphate, magnesium oxide, and potassium phosphate.
It is believed that the presence in the composition of
only minute traces of magnesium and potassium salts will be
sufficient to stimulate the release of adequate supplies of
these salts from the body's own stores. An alternative
explanation of the effectiveness of the compound of the
2
WO 94/27449 ~ ~ ~ PCTINZ94/00042
present invention is that the body requires only minute traces
of the magnesium and potassium salts to make up the
deficiencies caused by alcohol. However, a higher proportion
of magnesium and potassium salts may be advantageous. One or
more potassium salts and one or more magnesium salts may be
used.
Also, it is believed that the magnesium and potassium
salts and vitamin C are much more readily and easily absorbed
into the system if taken into the system with monohydrate
dextrose or glucose:- the monohydrate'dextrose or glucose
effectively coats said other constituents and prevents them
from being destroyed by stomach acids, and also speeds their
circulation around the system.
Zinc oxide assists the pancreas with the production of
insulin, and hence facilitates the absorption of glucose into
the blood. Zinc oxide also is known to be effective in
detoxifying the system i.e. combatting the after-effects of
alcohol.
It is believed that the presence of vitamin B6 in the
composition considerably increases the rate of activity of the
composition and thus gives more rapid relief to a user. It
appears that vitamin B6 and magnesium salts are synergistic
i.e. the presence of one increases the effectiveness of the
other, and thus reduces the amount of each needed in the
composition to achieve the desired effect.
Thus, the constituents of the composition act to raise
the user's blood sugar level and replenish lost vitamin C,
3
WO 94/27449 PCT/NZ94100042
2162877
magnesium and potassium, and also interact with each other to
mutually increase their effectiveness and to speed their
assimilation into the system.
Optionally, the composition also may contain one or more
of the following:
(a) 0. 5 % - 2 % by weight powdered citric acid, to improve
the palatability of the composition;
(b) 0.5% - 5% by weight powdered calcium phosphate, to
replenish calcium losses.
A preferred embodiment of the present composition
comprises:
(a) 2.4% ascorbic acid:
(b) 1.1% citric acid;
(c) 0.4% vitamin B6;
(d) 0.1% magnesium sulphate;
(e) 0.1% potassium phosphate;
(f) 0.1% magnesium oxide;
(g) 0.03% zinc oxide;
(h) 95.77% monohydrate dextrose;
(all % by weight).
The composition is in the form of a powder, and is
taken dissolved in water or in tablet form. It has been found
that the composition is more effective if the user lies on the
right side after taking the composition, because this allows
the composition to pass more quickly though the duodenum into
the intestine, for absorption into the system.
Alternatively, the composition may be prepared in liquid
4
Image
