PREPARATION ANTI-INFLAMMATOIRE

ANTI-INFLAMMATORY PREPARATION

Abrégé anglais

ABSTRACT OF THE DISCLOSURE
An anti-inflammatory preparation particularly
effective in relieving and curing pain originating from burns,
sunburn, insect bites and abrasions. The preparation is applied
topically as an ointment or lotion and consists essentially of
limewater (CaCO3) and edible oils selected from olive oil;
safflower oil, soya oil, corn oil and cottonseed oil.

Revendications

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A topical preparation for treating burns and
other skin irritations comprising a mixture containing 40 to
60 per cent by weight of an edible oil selected from the group
of olive oil; safflower oil, soya oil, corn oil and cottonseed
oil and the balance calcium carbonate.
2. The preparation of Claim 1, containing from 40
to 60 percent by weight of olive oil, the balance calcium
carbonate.
3. The preparation of Claim 2, wherein said calcium
carbonate is in the form of lime water.
4. The preparation of Claim 1, in ointment form.
5. The preparation of Claim 1 in solution form.
6. The preparation of Claim 4 containing up
to 10 per cent by weight of petroleum jelly.

Description

iO369~1
I` I l~:LI~ OF Tl I [' I NVI ,N'I' I ON
The prcsc~nt invcntion rc~t~s to a pharmac~llt:i~c
preparation for relieving and healing symptoms produced by
burns, scraping of the skin and insect bites.
Many emollient and anti-inflammatory preparations
already are on the market. These range from varioussteroid
derivatives to calamine-type lotions. ~s regards the former
and related compounds, some produce undesirable or allergenic
side effects. Moreover, they are generally quite expensive.
The latter are not too effective where the irritation is severe.
The present invention provides a pharmaceutical
composition for topical application against irritations and
inflammations caused by various conditions.
According to the present invention there is provided
a topical preparation for treating burns and other skin irrita-
tions comprising a mixture containing 40 to 60 per cent by weight
of an edible oil selected from the group of olive oil; safflower
oil, soya oil; corn oil and cottonseed oil and the balance
calcium carbonate.
The composition of the invention thus suitably
comprises a mixture of an edible oil and lime water. Various
pharmaceutically acceptable inert excipients can be mixed with
the two active ingredients as required.
The lime water is made by stirring calcium carbonate
in water in any proportion desired. Where the present composition
is to be dispensed as a paste or ointment, very little water
will be used to slurry the calcium carbonate so that when it
is finally mixed with the edible oil there will result a paste-
like substance. The preferred oil is olive oil.
The olive oil used is commercially available as
ordinary cooking oil. Its typical analysis is: mixed glycerides
of oleic acid 83.5%; of palmitic acid 9.4%; of linoleic acid
~`' - 1 - .

~o3694~L
4.0~,; of ste.lric acicl 2 0%; of arachidic acicl 0.9~ together
with up to 0.7~ of squalene and about 0.2~ of phytosterol arld
tocopherols.
The composition o~ the invention will contain from
40 to 60 percent by weicJht of oil, the balance lime water. A
preEerred composition which has given excellent results
contains equal amounts by welght of olive oil and lime water.
The edible oil may also be safflower oil, soya oil, corn
oil or cottonseed oil.
As above indicated, the composition may be in
the form of a paste or ointment (together with up to 10% of
petroleum jelly to improve its adherence to the skin) or it
may be in liquid form with, if needed, a liquid vehicle such
as non-toxic alcohols, glycerine or the like.
The preparation has been found to give cooling and
soothing relief in minutes in cases of sunburn. With other
burns, the preparation does not shrink the skin in the burn
area thus preventing unsightly scars. It also does not bind
joints.
The composition is applied ot the affected skin area
as directed by the prescribing physician. Generally two or
three applications per day constitute a practical dosage, for
humans and warm-blooded animals.