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Sommaire du brevet 1064355 

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Disponibilité de l'Abrégé et des Revendications

L'apparition de différences dans le texte et l'image des Revendications et de l'Abrégé dépend du moment auquel le document est publié. Les textes des Revendications et de l'Abrégé sont affichés :

  • lorsque la demande peut être examinée par le public;
  • lorsque le brevet est émis (délivrance).
(12) Brevet: (11) CA 1064355
(21) Numéro de la demande: 1064355
(54) Titre français: APPAREIL DE VACCINATION MULTIPENETRANT
(54) Titre anglais: MULTIPENETRANT VACCINATION APPARATUS
Statut: Durée expirée - au-delà du délai suivant l'octroi
Données bibliographiques
(51) Classification internationale des brevets (CIB):
  • A61B 17/20 (2006.01)
(72) Inventeurs :
  • CHACORNAC, GEORGES
(73) Titulaires :
  • MANUFACTURE FRANCAISE D'ARMES ET CYCLES DE SAINT-ETIENNE MANUFRANCE
(71) Demandeurs :
  • MANUFACTURE FRANCAISE D'ARMES ET CYCLES DE SAINT-ETIENNE MANUFRANCE
(74) Agent:
(74) Co-agent:
(45) Délivré: 1979-10-16
(22) Date de dépôt:
Licence disponible: S.O.
Cédé au domaine public: S.O.
(25) Langue des documents déposés: Anglais

Traité de coopération en matière de brevets (PCT): Non

(30) Données de priorité de la demande: S.O.

Abrégés

Abrégé anglais


ABSTRACT
Multipenetrant vaccination apparatus in which
a variable number of skin-penetrating tines may be selected
according to the patient be vaccinated. The base of the apparatus
has a series of stepped projections which receive a corresponding
series of hollow support cylinders in press-fit relationship.
Each support cylinder has tines extending from the free end
and by selecting a certain number of support cylinders the
appropriate vaccination area is obtained. The base may be
formed with an axial bore to receive a flexible capsule of
vaccine and a protective cap can be provided for the apparatus.

Revendications

Note : Les revendications sont présentées dans la langue officielle dans laquelle elles ont été soumises.


THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. Multipenetrant vaccination apparatus for dispensing
an amount of vaccine adapted to a particular patient in response to
a single application of pressure through the skin comprising a base
having a gripping and pressure receiving portion at one side thereof
and means including a central support receiving an assembly of con-
centric, hollow, support cylinders at the other side, the free ends
of the support cylinders and the central support having skin-penetrat-
ing tines thereon.
2. Vaccination apparatus according to claim 1 in which
the outer ends of the support cylinders lie in a single plane.
3. Vaccination apparatus according to claim 1 in which
the outer ends of the support cylinders extend to different levels
in staggered relationship, with the central support being the short-
est.
4. Vaccination apparatus according to claim 2 or claim
3 in which the tines are all of the same length.
5. Vaccination apparatus according to claim 2 wherein
the tines are of differing length with the tines on the central
support being the shortest, the tines on a support cylinder of
greatest diameter being the longest and the tines on an inter-
mediate support cylinder being of intermediate length.
6. Vaccination apparatus according to claim 1, wherein
the means receiving the support cylinders includes a series of
stepped projections, the central support being the projection of
smallest diameter, the support cylinders being press-fitted at one
end against intermediate projections in the series.
7. Vaccination apparatus according to claim 1,claim 2
or claim 3 wherein the central support is a projection received in
cm/
14

a bore on the base and the support cylinders are received in con-
centric grooves on the face of the base.
8. Vaccination apparatus according to claim 6 wherein
the support cylinders have a conical exterior surface and a dimin-
ished wall thickness at the side abutting the corresponding pro-
jection, in order to facilitate removal.
9. Vaccination apparatus according to claim 8 wherein
the means receiving the support cylinders is dimensioned to provide
a narrow space between the central support and the smallest support
cylinder and between adjacent support cylinders to retain vaccine
therein.
10. Vaccination apparatus according to claim 6 wherein
a projection on the base receives a protective cap in press-fitted
sealing relationship covering the assembly and providing a reservoir
for vaccine.
11. Vaccination apparatus according to claim 1, claim 2
or claim 3 wherein the arrangement of support cylinders gives maximum
innoculation on minimum skin surface, the arrangement of the tines
being circular or able to be inscribed in a circle.
12. Vaccination apparatus according to claim 1 wherein
the support cylinders are provided with enlarged portions adjacent
their free ends forming conical contact surfaces therebetween.
13. Vaccination apparatus according to claim 12 in which
the conical surfaces, the support cylinders and related chamfers on
the central support and protective cap constitute a sealed closure
retaining vaccine in the base of the protective cap in contact with
the tines.
14. Vaccination apparatus according to claim 12 in which
the support cylinders are roughened by grooves or striations giving
a gripping surface to aid in assembly and disassembly.
15. Vaccination apparatus according to claim 1 in which
cm/

the tines have beveled extremities to facilitate penetration and
provide a surface to retain vaccine.
16. Vaccination apparatus according to claim 15 in
which the beveled tines are provided with cavities to retain a
quantity of vaccine therein.
17. Vaccination apparatus according to claim 1 in which
the tines are formed with edges extending radially in section.
18. Vaccination apparatus according to claim 17 in which
the tines are of cruciform cross section.
19. Vaccination apparatus according to claim 17 or claim
18 in which vaccine is retained along the surfaces between the sharp
edges by surface tension.
20. Vaccination apparatus according to claim 1, claim 2
or claim 3 in which the central support has an axial opening in
order to receive a capsule of vaccine so that in a single operation
the tines perforate the skin and introduce the vaccine.
21. Vaccination apparatus according to claim 20 wherein
the ends of the tines define a surface convex with respect to the
axis of the device in the direction of penetration of the tines,
the longest tines on the central support being those first con-
tacting the skin.
22. Vaccination apparatus according to claim 20 wherein
the protective cap is removably retained on the support cylinder
of greatest diameter by a press-fit or a screw threaded connection.
23. Vaccination apparatus according to claim 20 wherein
the base is provided with projecting wing and the support cylinders
with circular collars to aid in assembly and disassembly.
24. Vaccination apparatus according to claim 23 wherein
the vaccine supply is a flexible capsule having a conical end with
a frangible sealed portion adapted to be received in the axial
opening of the central support.
18

25. Vaccination apparatus according to claim 20 wherein
the vaccine is contained in a flexible capsule having a conical end
with a frangible sealed position adapted to be received in the axial
opening of the central support and further including an extension
yoke with a head positioned above the axial opening to receive the
capsule.
26. Vaccination apparatus according to claim 20 wherein
the capsule is a syringe permitting innoculation of a controlled
amount of vaccine.
27. Vaccination apparatus according to claim 20 wherein
the base, the support cylinders and the cap are protected prior to
use by a sealed box or a sealed thermoplastic container, the assembly
being sterilized.
28. Vaccination apparatus according to claim 23 wherein
at least the collars and wings of the support cylinders are formed
of different colors in order to facilitate assembly and disassembly
of the apparatus.

Description

Note : Les descriptions sont présentées dans la langue officielle dans laquelle elles ont été soumises.


~64355
The present inven-tion relates to vaccination
apparatus and, in particular, to multipenetrant vaccination
apparatus.
Such multipenetrant vaccination apparatus functions
by having a number of tines or teeth dipped in vaccine ~hich are
then pressed against the skin so as to penetrate it. It is known,
however, that the innoculation must be gauged with respect to the
age of the patient, the older subject requiring more vaccine.
Generally, this leads to the necessity of vaccinating several differ-
ent areas. The effect is disagreeable if not unpleasant for thepatient who will show scars for a relatively extended time. The
procedure is not easy for the operator and involves a loss of time.
According to the invention there is provided multi-
penetrant vaccination apparatus for dispensing an amount of vaccine
` adapted to a particular patient in re~ponse to a single application
of pressure through the s~in. The apparatus comprises a base having
a gripping and pressure receiving portion at one side thereof and
means including a central support receiving an assembly of concen-
tric, hollow, support cylinders at the other side. The free ends
of the support cylinders and the central support have skin-penetrat-
ing tines thereon.
According to a specific embodiment the support
; cylinders can be engaged in concentric groove~ formed in the base
with the central projection solidly mounted therein. A protective
cap may be used having an enlarged portion with conical contact sur-
faces so as to seal against the support cylinders and prevent the
vaccine escaping from the base of the cap. This enlarged portion
also makes the cap more riyid and facilitates removal.
According to another variation the tines may have
- 30 a cross section with radial extending edges. These tines may also
have a cruciform cross section and be provided at the penetrating
- . ~, . . . . . . . .

1064355
end with sides or cavities to retain vaccine by surface tension.
According to another variation the base has a
single central projection with several tines at the free end. A
support cylinder is adapted to be retained on this projection in
a removable manner by press fit or by threaded means. Tines are
also provided at the free end of the support cylinder. The central
projection of the base defines an aperture adapted to receive a
flexible container of vaccine which is to be deposited on the skin
of the patient either before or when the tines are pressed through
the skin.
These features will become clearer from consider-
ation of the following description takin in conjunction with the
drawings.
Brief Description of the Drawi.~gs
Figure 1 is an exploded view, in perspective, of
vaccination apparatus according to the invention.
Figure 2 is a view on a larger scale of the assembled
apparatus.
Figure 3 is a sectional view of the assembled
apparatus.
Figure 4 is a view taken along arrow F in Figure 3
showing only the positioning of the tines on their support cylinders.
Figures 5 and 6 are sectional side and end views
showing the apparatus after removal of one support cylinder.
Figures 7 and 8 are side and end views showing the
; apparatus after removal of two support cylinders.
Figure 9 is a view in section of another embodiment
of the invention.
Figure 10 is a view taken along the direction of
arrow Fl in Figure 9 showing only the support cylinders.
Figure 11 is a partial section view showing the
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1064355
arrangement of tines in another embodiment.
Figure 12 is an exploded view showing a further
embodiment of the invention.
Figure 13 is a view in section of the assembled
apparatus of Figure 12.
Figures 14 through 24 show different forms of the
tines useful in the vaccination apparatus.
Figure 25 is a view in section of a further embodi-
ment of the invention.
Figure 26 is a plan view of the apparatus shown
in Figure 25.
Figure 27 shows one form of vaccine container.
Figure 28 shows the vaccination apparatus placed
in a protective cover.
Figure 29 is an exploded view of the elements making
; up the apparatus of Figure 25.
Figure 30 is a plan view showing a variation of the
, apparatus with additional gripping members.
Figure 31 is a view in section of another form of
- the apparatus.
Figure 32 is a plan view of the apparatus of Figure
; 31.
F~`gure 33 is a different form o vaccine container
particularly adapted to be used with the apparatus of Figure 31.
,~ Figure 34 is a different form of vaccine container
in the form of a syringe.
Figures 35 and 36 give two examples of operation of
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10643S5
Description of the Preferred Embodiments
The apparatus shown in Figures 1 to 8 consists of a
body section 1 having a flat gripping member la joined to a flat
circular base lb. A series of staggered cylindrical projections
lc, ld, le, lf ... project from the base at the opposite side to
the gripping member.
The first projection, lc, is adapted to receive the open
end of a protective cover 2 in press-fitted sealing relationship.
The lower part of the cover forms a reservoir for the vaccine to
be innoculated. The conical shape of the cover facilitates its
fastening on the projection. The cover may be omitted, in which
case the vaccine is carried in a separate container.
The furthest extending projection lf has tines in the
form of points, teeth or other projections lg on one end giving a
"
; roughened surface. A suitable number, typically five, may be
~ provided as shown in Figure 4. The intermediate projections such
- as ld and le receive hollow support cylinders 3 and 4 in press-
fitted relationship abutting on the respective upper shoulders.
The free ends carry tines in alignment with each other. A suitable
number, typically nine on cylinder 3 and eighteen on cylinder 4,
.. . .
are provided as shown in Figure 4.
The support cylinders, being hollow, define a cylindrical
bore therein and have a conical outer surface with the larger
diameter at the tine-supporting end. With the particular spacing
of the cylindrical projections, this creates a small space E
between the support cylinders and between cylinder 3 and projec-
tion lf, which serves to retain a quantity of vaccine. The
.~ .
~ conical shape of the hollow cylinders aids in positioning and
: :
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,.: . . . .
. ~ . ,, . , .. ,. . ~ ..

-` 106435S
removing them irom the projections because the wall is thinner at
the top end. As shown in Figures 5 - 8, it is straightforward to
change the number of tines to suit the patient being vaccinated by
removing one of the cylinders (as shown in Figures 5 and 6) or two
cylinders as shown in Figures 7 and 8.
Thus when the apparatus is assembled with all the tines,
the maximum possible vaccination is achieved with only one pene-
tration of the skin. If it is desired to innoculate less vaccine,
one or more of the cylinders can be removed. For the minimum
vaccination, only the projection lf is used.
The support cylinders and the projections are circular
in section for ease of manufacture and to provide a concentration
of tines in order to obtain the maximum innoculation on minimum
skin surface. It will be clear, however, that other configura-
tions can be manufactured in which the projections and cylinders
are in polygonai form, for example with a square or hexagonal
section.
Figures 9 and 10 illustrate a further embodiment in
which the base 5 has only one projection 5a to receive the protec-
tive cover 6. On the flat face of this projection is formed anaxial bore 5b to receive a support cylinder 7 equipped with tines
-~ 7a. Circular grooves 5c and 5d are formed concentric with this
bore, to receive hollow support cylinders 8 and 9 fitted with
tines 8a and 9a. It will be clear that this embodiment could,
alternatively, be formed with a central projection instead of
; support cylinder 7.
It will also be noted that instead of the tines being
`I all of the same length, they may be formed in different lengths as
shown in Figure 11. In this figure, the shortest tines 10 are at
, .
-- 5 --
,, .
: . : . .; , .: . - .
. : - ~ , .,. . : .
.. . . .

` ~064355
the centre and the longest tines 11 at the outside, with inter-
mediate tines shown at 12. The same effect can be obtained by
providing tines of equal length with the supporting cylinders
being of different lengths (in apparatus of the type of Figure 9)
or extending to different levels (in apparatus of the type of
Figure 3). This different penetration of tines permits the
selection of a particular depth of innoculation for any particular
patient. As an example of the invention, but not limited to it,
a typical vaccination device has the following dimensions:
Length - (approximately) 39 millimeters
Exterior diameter - (approximately) 12 millimeters
Length of the - (approximately) 17 millimeters
grippinc member
Length of the tines - (approximately) 3 millimeters, or
3, 2.8 and 2.5 millimeters if they
are of different lengths
Conical angle of the - (approximately) 2
support cylinders
Space between the - (approximately) .5 millimeters
support cylinders
The selection of such dimensions permits the patient to
be innoculated with the correct quantity of vaccine by adjustment
of the movable elements. Vaccination is thus achieved with a
precise amount having regard to the age of the patient and with a
single penetration of the skin. The concentration of innoculating
tines provided by the particular arrangement tends to the maximum
innoculation possible on a minlmum surface of skin which avoids
scarring. The spacing between the support cylinders provides for
the storage of some vaccine.
In Figures 12 and 13 a further embodiment of the
vaccinating apparatus is shown in which the base supports an
' '
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1064355
arrangement of movable hollow support cylinders. In the arrange-
ment shown, the cylindrical support cylinders are arranged in
staggered fashion on the base, but it will be clear that the
support cylinders could be positioned and supported by concentric
circular grooves, as previously described.
The base 13 has a gripping member 13a formed as a flat
projection terminating in a circular disc 13b. Staggered cylin-
drical projections 13c, 13d, 13e, 13f and 13g extend from the
opposite sides. The first projection 13c receives the open end
of a protective cover 14 in a press-fit relationship. The other
end of the cover retains the vaccine to be used.
Projec-tion 13g has on its face a suitable number of
tines or points 15 to provide the normal roughened penetrating
surface. A suitable number of intermediate projections 13d and
`1 13e are provided and have press-fitted thereto hollow support
-~ cylinders 16 and 17 having at their free ends a suitable number
of tines 18-19. Support cylinders 16 and 17 have enlarged por-
tions adjacent their free ends forming shoulders 16a and 17a
having conical contact surfaces. Similar conical surfaces are
formed by a chamfer 13h between projections 13f and 13g and a
chamfer 14a on the inner surface of cover 14. As a~ alternative
arrangement, the shoulders can be formed with contact faces per-
pendicular to the axis of the device.
;l The contact surfaces ensure efficacious sealing of the
assembly to avoid escape of the vaccine along the gap between the
~ supporting cylinders during manipulation. That is, support
,~ cylinder 16 is fitted on projection 13e and abuts on surface 13h.
Support cylinder 17 is fitted on projection 13d and abuts on
. surface 16a of cylinder 16. The cover i5 supported on projection
, ~ _ 7

106~355
13c and abuts on the surface of shoulder 17a of supporting
cylinders 17.
It will be noted that to aid the support and disengage-
ment of the cylinders, the surface can be roughened as by grooves
16b-17b or other fluting or a checkerboard pattern. The conical
arrangement of the supporting cylinders adds to the rigidity of
the assembly and facilitates assembly and disassembly.
Thus, a particular feature of the device shown in
Figures 12 and 13 is the sealing effect, both at the shoulders
where the supporting cylinders fit and between the conical con-
tact surfaces 13h - 16a - 17a - 14a, which prevents the vaccine
from escaping along the length of the supporting cylinders. The
shoulders provided on the supporting cylinders add to the rigidity
of the device, particularly diametrically. When positioning each
supporting cylinder in assembling of the device, it engages with
the previous cylinder and consequently seals the unit. The
arrangement of the shoulders or reinforcing portion provides in
effect a lengthening of the portion of the supporting cylinder
being gripped when it is being moved, and thus avoids having
~ingers in contact with the vaccine and the tines. The tines of
different lengths ~preferably shorter towards the centre) assure
a progressive penetration of the skin with a re~uced pressure,
thus greatly diminishing or eliminating unpleasant sensations
experienced by the patient.
Th~ roughened surface provided to penetrate the skin is
preferably formed from tines such as sharp teeth or points. As
shown in Figures 14 through 24, different forms of these tines
can be provided having equal or unequal length. For example,
Figures 14, 15 and 22 illustrate tines 20 having in section three
- 8 -
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1064355
or four sharp edges which can be joined by plane, convex or con-
cave sides. In Figures 16 and 17 the tines 21 have a cruciform
section with thin edges. In Figures 18 and 19 the tines 22 have
a cruciform section with thick edges, and in Figures 20 and 21
the tines 23 have a cruciform section with thick edges and either
convex or concave curved faces therebetween. In Figure 22 the
tines 25 are shown as having a polygonal section with concave
surfaces. In these various forms the sides of the tines between
the edges serve to retain vaccine. Finally, Figures 23 and 24
show a further variation in which the tine 24 is formed from a
cylindrical needle with a bevelled end 24a forming one or more
concave cavities 24b.
The side faces of the tines between the radial edges,
being of cruciform, bevelled or faceted shape, or having cavities
or reservoirs, permit the retention of vaccine in the faces.
.~.
Alternatively, internal cavities can be formed on straight or
curved faces. In each case the vaccine is retained by the effect
of surface tension. The tines or roughened surface form a pene-
tration surface equivalent to a much larger area which permits
the reduction in the number of tines used without causing a
`, capillary effect by extremely close spacing of the tines. Optimum
penetration of the vaccine is achieved due to the radial edges
of the tines opening the skin in a manner which avoids the edges
of the skin closing or wiping off the vaccine contained in the
side surfaces or cavities.
Figures 25, 26, 28, 29, 35 and 36 show another form of
the vaccination apparatus, in which the device includes a base 26
having a central cylindrical projection 26a with a reducing
stepped diameter carrying at one end at least one, but preferably
several, tines. The base is also formed with a shoulder 26c and
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-

10643S5
extends outwardly by means of two diametrically opposed wings or
projections 26d. A conical passage 26e in the base communicates
with an orifice 26f in the lower portion. A support cylinder 27
is frictionally engaged by fitting its bore 27a to the step
portion 26a of the base. Support cylinder 27 has a collar 27b
abutting against shoulder 26c of the base and has tines 27c at
the free end.
- Other support cylinders can be used,frictionally engaged
with support cylinder 27. In the particular embodiment illus-
trated, only one support cylinder is provided, the outer diameter
27d of this cylinder receiving a protective cover 28 in a press-
fit relationship. The cover gives mechanical protection to the
tines to avoid wear by rubbing or friction, and bacterial protec-
tion by ensuring that they remain sterilized. To maintain the
sterile condition, the opening 26e in the base is covered when the
device is contained in a case E (Figure 28).
It will be noted that tines 26b and 27c are of different
, lengths with the tines 26b closest to the axis of the base being
the longest and the tines situated furthest from the axis being
':
` 20 the shortest, thus defining an imaginary surface P (Figure 5)
` convex with respect to the axis in the direction of penetration
`~ of the tines.
Figure 27 shows a container for the vaccine to be
innoculated. It consists of a flexible capsule 29 having a
; reservoir portion 29a terminating in a conical end 29b adapted
to be received in the bore 26e of the base and having a frangible
`~ sealed end 29c. The conical portion 29b and the bore 26e are
formed to conventional standards and may, for example, conform to
French standard S90011. -
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1064355
Figures 31 and 32 illustrate another form of the inven-
tion in which the vaccination device has, as before, support
cylinders 27 and a protective cover 28, while the base 30 has a
central opening 30a with tines 30b. Also, cylindrical shoulder
30c, wings or projections 30d, conical bore 30e with the outlet
` orifice 30f, are provided. The upper portion of the base opposite
shoulder 30c is formed with a boss 30g from which two ribs 30h
extend vertically, joining together at a head 30i. The ribs lie
outside a cylinder of a diameter defined by the bore 30j of ~he
head 30i and by opening 30k in boss 30g leading to the conical
bore 3Oe.
This particular form of base is adapted to receive and
guide a vaccine container such as is shown in Figure 33 in the
~ .~
` form of a flexible tube 31 having a reservoir portion 31a leading
to a conical end 31b adapted to be received in the bore 30e of
the base and with a frangible sealed end 31c.
i Figure 34 illustrates a syringe type of vaccine container
:`! 32 having a body forming a reservoir 32a for the vaccine ending
in a conical portion 32b corresponding to the conical bore formed
in the base. The syringe type container also has a piston 32c.
This container permits a controlled distribution and dosage of
,.j
the vaccine as required by the practitioner for any individual
patient. It will be noted that the flexible tube 31 and the
syringe 32 can be also used with the vaccination device previously
described. It will be noted that the apparatus is easily handled,
since the wings 26d and 30d on the base permit it to be easily
separated from the support cylinder 27 when the upper collar 27b
abuts on the cylindrical projections 26c or 30c of the base
(Figures 26 or 32). It can be seen that the support cylinders
- 11-
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1064355
also have wings 27e, 27f (Figure 30) positioned angularly with
respect to the wings 26d of the base to aid in their removal.
Additionally, different colours can be provided for the
base and the support cylinders in order to facilitate their
assembly. This differentiation in colour can be provided ~or all
the elements or only on the wings or collars of the pieces.
The operation of the vaccination device of this inven-
tion will now be described with reference to Figures 31, 35 and 36.
In Figure 35 a complete vaccination de~ice is shown having the
maxim~n n~nber of tines and with a capsule of vaccine 29 fric-
tionally engaged therein. The practitioner holds the capsule
between the th~,nb and first finger and presses the vaccination
device on the skin of the patient, pressing in on the sides of the
capsule (arrows Fl, F2), the ends of the thumb and finger used for
pressing being in contact with the wings of the base. The vaccine
thus flows out through orifice 26f into the space between the
tines and a certain quantity penetrates into the epidermis.
Alternatively, the capsule may be frictionally engaged
in the bore 26e and held by the practitioner between the index
finger and middle finger to press in on the capsule and apply
pressure on the wings of the base (Figure 36 which shows only the
base in use), so that the thumb passes behind the arm so that the
hand applies appropriate pressure to the device~
~! ' With the flexible tube 31, the action is similar in that
the practitioner holds the tube frictionally engaged in the base
(broken line in Figure 31) and presses the apparatus on the skin
while pressing the tube. If the practitioner wishes to employ
a graduated syringe such as 32, he holds the vaccination device-
syringe assembly in one hand,and pressing against the skin,
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1064355
operates ~he piston 32c of the syringe with the other hand in
order to deliver a particular dosage of the vaccine.
The advantages of the device according to the invention
will be clear. In particular, it can be noted that the assembled
device can be easily manipulated as can the elements be removed
by means of the wings, the collars, or the different colours. A
precise dosage of vaccine is available, being introduced into the
device at the time of penetration, avoiding losses in areas
between the tines, the cylinders and the base. The sterile con-
dition of the apparatus and of the vaccine container will be noted.The initial penetration by the central tines, then the outer tines,
gives the most ffective vaccination because the vaccine is first
introduced in the central part.
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Dessin représentatif

Désolé, le dessin représentatif concernant le document de brevet no 1064355 est introuvable.

États administratifs

2024-08-01 : Dans le cadre de la transition vers les Brevets de nouvelle génération (BNG), la base de données sur les brevets canadiens (BDBC) contient désormais un Historique d'événement plus détaillé, qui reproduit le Journal des événements de notre nouvelle solution interne.

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Historique d'événement

Description Date
Inactive : Périmé (brevet sous l'ancienne loi) date de péremption possible la plus tardive 1996-10-16
Accordé par délivrance 1979-10-16

Historique d'abandonnement

Il n'y a pas d'historique d'abandonnement

Titulaires au dossier

Les titulaires actuels et antérieures au dossier sont affichés en ordre alphabétique.

Titulaires actuels au dossier
MANUFACTURE FRANCAISE D'ARMES ET CYCLES DE SAINT-ETIENNE MANUFRANCE
Titulaires antérieures au dossier
GEORGES CHACORNAC
Les propriétaires antérieurs qui ne figurent pas dans la liste des « Propriétaires au dossier » apparaîtront dans d'autres documents au dossier.
Documents

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Description du
Document 
Date
(aaaa-mm-jj) 
Nombre de pages   Taille de l'image (Ko) 
Page couverture 1994-04-28 1 24
Abrégé 1994-04-28 1 23
Dessins 1994-04-28 6 196
Revendications 1994-04-28 4 174
Description 1994-04-28 13 565