Note : Les revendications sont présentées dans la langue officielle dans laquelle elles ont été soumises.
THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A hydrophilic polyurethane polymer comprising the
reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids:
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
2. The polyurethane polymer of claim 1, wherein one
of said diols is a difunctional linear polyester derived from the
condensation of one or more diols with one or more dibasic acids.
28
3. The polyurethane polymer of claim 1, wherein one of
said diols is the reaction product of a polyoxyalkylene diol
with a difunctional linear polyester derived from the condensation
of diethylene glycol with adipic acid.
4. A surgical suture comprising a hydrophilic poly-
urethane polymer obtained by reacting.
(A) one or more diols having an equivalent weight in
the range of from about 100 to 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
29
5. The suture of claim 4, wherein said hydrophilic
polyurethane polymer is in the form of a monofilament.
6. The suture of claim 4, wherein said hydrophilic
polyurethane polymer is in the form of a braided multifilament.
7. The suture of claim 4, having present in said
hydrophilic polyurethane polymer a medicament.
8. The suture of claim 7 wherein said medicament is
iodine.
9. A burn dressing comprising a hydrophilic polyurethane
polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-
m being an integer from 2 to 10; and ethers
derived from said lactones: and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
10. The burn dressing of claim 9 wherein said
hydrophilic polyurethane polymer is in the form of a film.
11. The burn dressing of claim 9 wherein said hydro-
philic polyurethane polymer is in powder form.
12. The burn dressing of claim 9 wherein said
hydrophilic polyurethane polymer is in solution.
13. The burn dressing of claim 10 having present in
said hydrophilic polyurethane polymer a medicament.
14. The burn dressing of claim 13 wherein said medica-
ment is sulfadiazine.
15. The burn dressing of claim 11 wherein a medicament
is distributed throughout the powder.
16. The burn dressing of claim 12 wherein a medicament
is dissolved in said solution.
17. A surgical implant comprising a solid hydrophilic
polyurethane polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
31
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates;
said polyurethane polymer having distributed throughout its
mass a medicament.
18. The implant of claim 17 wherein said medicament
is an anti-tubercular drug.
19. The implant of claim 17 wherein said medicament
is a drug protagonist.
20. The implant of claim 17 wherein said medicament
is a hormone.
21. The implant of claim 17 wherein said medicament
is a steroid.
22. The implant of claim 17 wherein said medicament
is a vitamin.
23. An intrauterine device comprising a hydrophilic
polyurethane polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000
selected from the group consisting of:
32
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2-NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
24. The intrauterine device of claim 23 in the shape
of a ring.
25. The intrauterine device of claim 23 having
distributed throughout said polyurethane polymer a contraceptive.
26. The intrauterine device of claim 25 wherein the
contraceptive is lactic acid.
27. A canula, the walls of which are formed of a
hydrophilic polyurethane polymer obtained by reacting:
33
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH20H; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
28. The canula of claim 27 wherein said polyurethane
polymer has distributed throughout its mass a medicament.
29. The canula of claim 28 wherein said medicament
is iodine.
34
30. A canula woven of textile fiber in the form of
a tube having external and internal walls, at least one wall of
which is coated with a film of a hydrophilic polyurethane
polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH20H; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
31. A vascular prosthesis comprising textile strands
woven in the form of a tube; the intersticies between said woven
strands being filled with a hydrophilic polyurethane polymer
comprising the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10, and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
36
32. The vascular prosthesis of claim 31 wherein said poly-
urethane polymer has distributed throughout its mass a medicament.
33. The vascular prosthesis of claim 31 wherein said
textile strands are polyethylene terphthalate strands.
34. The vascular prosthesis of claim 31 wherein said textile
strands are collagen strands.
35. The vascular prosthesis of claim 32 wherein said medi-
cament is heparin.
36. An oral delivery system comprising a pharmacologically
active agent and a hydrophilic polyurethane polymer as a carrier
vehicle therefor, said hydrophilic polyurethane polymer being the re-
action product of:
(A) one or more diols having an equivalent weight in the
range of from about 100 to about 3,000, selected from the group consis-
ting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the condensation
of one or more diols with one or more dibasic acids, and
(d) the reaction product of one or more alkylene diols with
a difunctional linear polyester derived from the condensation of one
or more diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from the group
consisting of -H, -CH2NH2, -SO2CH3, -CHOHCOOH, and -(CHOH)nCH2OH; n
being an integer from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers derived from said lactones;
and
37
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
37. A solution effective in the repair of skin
abrasions comprising a hydrophilic polyurethane polymer dissolved
in a volatile non-toxic organic solvent, said polyurethane
polymer being the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
38
38. A cosmetic adapted for topical application
comprising a solution of a non-toxic dye and a hydrophilic
polyurethane polymer in a volatile non-toxic organic solvent,
said-polyurethane polymer being the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
39
39. A surgical suture coated with a hydrophilic
polyurethane polymer comprising the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-:
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
40. An eye bandage comprising a hydrophilic
polyurethane polymer film obtained by reacting:
(a) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of: H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
41
41. A battery separator plate formed of a hydrophilic
polyurethane polymer comprising the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids,
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
42
42. A hair spray composition comprising a solution in
a volatile non-toxic solvent of a hydrophilic polyurethane
polymer obtained by reacting:
(a) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10, and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
43
43. A gas permeable membrane formed of a hydrophilic
polyurethane polymer comprising the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol)
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
44
44. A depilatory liquid comprising a solution in a
non-toxic solvent of a depilatory agent and a hydrophilic
polyurethane polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-,
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
45. A solution of perfume and a hydrophilic poly-
urethane polymer in a non-toxic solvent said polyurethane
polymer comprising the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids.
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2H2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
46
46. A corneal prosthesis comprising a solid transparent
hydrophilic polyurethane polymer obtained by the reaction of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2,-SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates,
said polyurethane polymer being in the shape of a lens and
characterized by a refractive index in the range of from about
1.39 to about 1.55; dry.
47
47. A deodorant composition comprising a solution of
a disinfectant, a perfume and a hydrophilic polyurethane polymer
obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
48
48. A method of imparting moisture to a dry gas
which comprises passing the gas through a tube formed of a
hydrophilic polyurethane polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
49
49. An antifogging liquid containing in solution a
hydrophilic polyurethane polymer comprising the reaction product
of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
50. A surgical drape comprising a fabric coated on
at least one side with a hydrophilic polyurethane polymer obtained
by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-,
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
51
51. A dialysis membrane formed of a hydrophilic
polyurethane polymer comprising the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
52
52. In a blood oxygenator the improvement which
comprises a carbon dioxide - oxygen exchange membrane formed
of a hydrophilic polyure-thane polymer comprising the reaction
product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-,
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
53
53. An amphoteric hydrophilic polyurethane polymer
comprising the reaction product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3, 000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) difunctional linear polyesters derived from
the condensation of one or more diols with
one or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-,
m being an integer from 2 to 10; and ethers
derived from said lactones;
(C) a.urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates; and
(D) a dialkanol tertiary amine.
54
59. An esophageal prosthesis constructed of a fabric
tube reinforced with a spirally wound polypropylene monofilament
and coated on at least one side with a hydrophilic polyurethane
polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difullctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group conslsting of -H, -CH2NH2, -SO2CH3,
CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
55. A contact lens comprising a molded hydrophilic
polyurethane polymer obtained by reacting:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000,
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2NH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-:
m being an integer from 2 to 10; and ethers
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile
carbonates.
56. The polyurethane polymer of claim 1 characterized
by a flow point below 275° C.
57. The polyurethane polymer of claim 1 characterized
by the presence of lactone groups and hydroxyl groups in the
polymer backbone.
56
58. The polyurethane polymer of claim 1 characterized
by the presence of carboxyl groups and hydroxyl groups in the
polymer backbone.
59. The polyurethane polymer of claim 1 which has
been molded to form a desired shape.
60. A coated device consisting of a substrate coated
with a hydrophilic polyurethane polymer comprising the reaction
product of:
(A) one or more diols having an equivalent weight in
the range of from about 100 to about 3,000
selected from the group consisting of:
(a) diethylene glycol,
(b) long chain polyoxyalkylene diols,
(c) linear polyester diols derived from the
condensation of one or more diols with one
or more dibasic acids, and
(d) the reaction product of one or more alkylene
diols with a difunctional linear polyester
derived from the condensation of one or more
diols with one or more dibasic acids;
(B) a polyfunctional lactone having the formula
<IMG>
wherein R1 is a monovalent radical selected from
the group consisting of -H, -CH2CH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-;
m being an integer from 2 to 10; and ethers
57
derived from said lactones; and
(C) a urethane precursor selected from the group
consisting of organic polyisocyanates and nitrile carbonates.
61. The coated device of claim 60 wherein the
substrate is a catheter.
62. A polyurethane polyether resin having lactone
groups in the polymer backbone.
63. The polyurethane polyether resin of claim
62 having hydroxyl groups in the polymer backbone.
64. A carrier system comprising an active agent
and a hydrophilic polymer as a carrier vehicle therefore,
said carrier vehicle comprising a polyurethane polyether resin
having free hydroxyl groups and carboxylate groups in the
polymer backbone.
65. In a method for releasing an active agent in
a medium in which said active agent is used the improvement
comprising:
incorporationg said active agent in a polyurethane
polyether resin having free hydroxyl groups and carboxylate
groups in the polymer backbone;
exposing said polyurethane with said active agent
to said medium; and
releasing said active agent into said medium at
a predetermined rate.
66. The method of claim 65 wherein the medium is-
water.
67. The method of claim 65 wherein the medium is a
gas.
68. The method of claim 67 wherein said gas is
air.
58
m~b/ ~J~
69. A polyurethane polyether resin characterized by a
molecular weight above 6000 and having lactone groups in the
polymer backbone, said urethane polymer comprising the reaction
product of:
(a) a polyfunctional lactone having the formula
<IMG>
wherein Rl is a monovalent radical selected
from the group consisting of -H, -CH2MH2, -SO2CH3,
-CHOHCOOH, and -(CHOH)nCH2OH; n being an integer
from 0 to 5; and R2 is a divalent radical -(CHOH)m-
m being an integer from 2 to 10; and ethers
derived from said lactones.
(b) a polyalkylene oxide glycol; and
(c) an organic polyisocyanate;
said urethane polymer being soluble in alkaline solutions.
70. The polyurethane polyether resin of claim 69
wherein said lactone is delta gluconolactone.
71. The polyurethane polyether resin of claim 69
wherein said lactone is mannolactone.
72. The polyurethane polyether resin of claim 69
wherein said lactone is sorbolactone.
73. The polyurethane polyether resin of claim 69
wherein said lactone is D-glucuronolactone.
74. The polyurethane polyether resin of claim 69
wherein said polyalkylene oxide is polyethylene glycol having
a molecular weight of 1450.
59
75. The polyurethane polyether resin of claim 69
wherein said polyalkylene oxide glycol is a mixture of
polyethylene glycol and dietllylerle glycol.
76. The polyurethane polyether resin of claim 69
wherein said polyalkylene glycol is a block copolymer polyol
characterized by a molecular weight of about 4750; said block
copolymer polyol being obtained by adding poly(oxyethylene)
groups to a poly(oxypropylene) chain having a molecular weight
of about 950.
77. The polyurethane polyether resin of claim 69
wherein said polyalkylene glycol is a block copolymer polyol
characterized by a molecular weight of about 7500; said block
copolymer polyol being obtained by adding poly(oxyethylene)
groups to a poly(oxypropylene) chain having a molecular weight
of about 2250.
78. The polyurethane polyether resin of claim 69
wherein said polyalkylene glycol is a block copolymer polyol
characterized by a molecular weight of about 6510; said block
copolymer polyol being obtained by adding poly(oxyethylene)
groups to a poly(oxypropylene) chain having a molecular weight
of about 2250.
79. The polyurethane polyether resin of claim 69
wherein said polyalkylene glycol is a block copolymer polyol
characterized by a molecular weight of about 13,333; said block
copolymer polyol being obtained by adding poly(oxyethylene)
groups to a poly(oxypropylene) chain having a molecular weight
of about 4000.
80. The polyurethane polyether resin of claim 69
wherein said polyalkelene oxide glycol is polypropylene glycol.
81. The polyurethane polyether resin of claim 69
wherein said polyisocyanate is methylene di(cyclohexylisocyanate).
82. The polyurethane polyether resin of claim 69
wherein said polyalkylene oxide is a polyethylene oxide having
a molecular weight in the range of 200 to
83. A photosensitive coating composition comprising
an alkaline solution of a polyurethane polyether resin having
free hydroxyl groups and carboxylate groups in the polymer
backbone and a catalyst which accelerates the cross-linking of
said resin when exposed to light.
84. The coating composition of claim 83 wherein the
catalyst is ammonium dichromate.
85. A photosensitive film comprising a layer of a
dichromate catalysed polyurethane polyether resin having free
hydroxyl groups and carboxylate groups in the polymer backbone
supported on a substrate to which it adheres.
86. A method of protecting and reducing the
hydrostatic drag of a surface which comprises applying thereto
a coating of a catalysed polyurethane polyether resin having
free hydroxyl groups and carboxylate groups in the polymer
backbone and exposing said resin coating to light.
87. A polyurethane polyether resin obtained by
reacting a mixture of polyethylene glycol, diethylene glycol,
delta gluconolactone and methylene di(cyclohexylisocyanate)
in the presence of a catalyst.
61
88. The polyurethane polyether resin of claim 87
obtained by reacting a mixture of about 54.6 parts of polyethylene
glycol (M. Wt. 1450), about 8.7 parts of diethylene glycol, about
5.8 parts of delta gluconolactone and about 40.4 parts of methyl-
ene di(cyclohexylisocyanate) in the presence of about 0.5 parts
dibutyl tin dilaurate.
89. A hydrostatic drag resistant coating composition
comprising an alkaline solution of a polyurethane polyether resin
having free hydroxyl groups and carboxylate groups in the polymer
backbone and a catalyst that accelerates the cross-linking of said
resin when exposed to light.
90. The coating composition of claim 89 having present
therein an effective amount of an anti-fouling agent.
91. A composition useful in the treatment of burns
comprising from about 1 to about 80 parts by weight of polyvinyl-
pyrolidone-iodide and from about 20 to about 99 parts by weight
of a polyether polyurethane resin having free hydroxyl and
carboxylate groups in the polymer backbone.
92. The polyurethane polyether resin of claim 62
whlch has been hydrolyzed to form carboxylate groups or
carboxyl groups in the polvmer backbone.
62