Note : Les descriptions sont présentées dans la langue officielle dans laquelle elles ont été soumises.
w o 91/18586 PCT/~S91/026X6
208~8~3
LIQUID ANTIPERSPIRANT COMPOSITIONS
TECHNICAL FIEL~
The ~resent invention relates to unique clear, sprayable,
liquid a,l.;oerspirant compositions having viscosities of less than
acou; lj centisco~es which are stable and ~hich pro~ide excellent
an~ieens~ ncy ~nd cosmetic in-use properties~
~ACKGROUNO OF T,~ I~VENTIC~
~nti~erspirant comoositions have becoma part of many people's
yel 50n~l rare and grooming regimen~ A highly desirable
antiperspirant composition will provide a number of benefits at
the same time. First and foremost of these is, of course,
antiperspirancy efficacy. Good usage aesthetics are also highiy
desirable. A composition that goes onto the skin easily without
dripping or running off is important. It is also desirable that
the composition goes onto the skin with a clean, dry, non-irrita-
ting, non-sticky feel. Upon dry-down preferred compositions will
leave minimized residue on the skin and clothing. Finally, it is
important that an antiperspirant composition remain both
chemically and physically stable over time and a broad range of
physical conditions, especially changes in temperature.
The formulation of antiperspirant compositions generally is
ar exercise in efficacy and aesthetic trade-offs, with the
resulting composition being acceptable overall, but not
outstanding. For example, the formulation of a composition to
give it good usage aesthetic properties (e.g., minimized
irritation to skin, minimized residue on the skin, and/or a clean,
dry ~nd non-sticky feel) often compromises antiperspirant
efficacy.
It is particularly difficul. to formulate an antiperspirant
composition which provides maximum usage aesthetics and efficacy,
when it is in the form of a low-viscosity liquid product~ such as
W O 91/18586 PcT/us9l/o26x6
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a spray-on antiperspir~nt c~mpositien~ an ~t th~ ~ame ti~
maintain good physical proper~ies (e.5.~ 5~a~ility over time and a
broad range of physical condit ons~ ~seeciallv changes in
temperature).
Non-~erosol ~1UmD S~ l'`t`~ ?~l COll'.i)CSl~i??,s ~ VQ
increased in popu7arity recentlv o~ ae-~osoi an;iperspirant
forms. Such antiperspi~ a~n ~ e~ have 'oeen ~i.clcsed
in~ fcr e~ample, ~ WJn. ;~.e~ isseee
October 1 1, 1~ 7 7; ù . ~? ~s s u e d
December 2~, 197i; IJ~ a~a~an e~ a , isaueG
february 14, 1g78; and ~rea; ~ritain ~D3l ication !,536.222
published ~ecember 2Q. 1~7~ ~
Pump spray anti~e,,pi al; ca-eaii'io ~ 9ène~^a`~ ;omp~ se
high levels of an alcohol solvent and little or no emollient
materials. Formulation in such a way 4enerally results in
products with poor in-use characteristics. That is, such compo-
sitions result in a sticky, cold, stinging feel upon application.
Often such compositions are too thin in consistency and tend to
run off of the skin after application. Generally, such composi-
tions will leave a residue on skin upon dry down.
Hence, it is an object of the present invention to provide alow Yiscosity, clear, sprayablê~ uid antipelspirant comsosition
which exhibits excellent antiperspirancy properties.
It is also an object of the present invention to provide a
low viscosity, clear, sprayable~ liquid antiperspirant composition
which exhibits excellent cosmetic in-us2 properties.
It is a further object of the present invention to provide a
low viscosity, clear, sprayable, liquid antiperspirant composition
which is physically and chemically stable over time and a broad
range of physical conditions.
These and other objects wlll become readlly apparent from the
detailed description which follows.
w o 9~/18586 PCT/~'S91/026X6
2082823
SUMMARY nf TH~ ~Nv~NTlON
The present invention rela~4s to clear~ sprayable, liquid
antiperspirant solutions~ having a viscosity of less than about 15
centistokes, comprising:
a. from about 1OX to ahout 2$~, of a monohydric alcohol-sol-
uble antiperspirant salt;
b. from abou. 0.5~, ta ~bo"t 2~V~ of 1 ncn-volatile ~mollient
e~t~r sel~ct~d ~ n .;~ v,~ v' ~ r~ ~' C.-C2c
alcohols and benzoic dClu~ es;ei`S 0; 2~-C,o alconoîs dnd
C6-Cl6 r^at~y acids, aild mli~u~as :. n~ ~ haYiny a solu~iiit~.
parameter of from about ~ to about i~;
c. from OX to abn!lt 1~ Oc ~ ~ra~l ene glvcol ether of
a C~-c22 fatty alcohol:
d. from oæ to about 20X of a ~olatile silicone emollienti
e. from 0% to about 3X of a pH buffer;
f. from 07. to about 4% of a mixture of a dimethicone
copolyol in a suitable solvent therefor;
f. from about 2X to about 10% of water;
9. from about 45X to about 65X of a monohydric alcohol
solvent; and
i. from OX. to about 2~ of a non-volatile dimethicone fluid
having a viscosity of less than about 20 centistokes;
and
j. from OX to about 6% of a Cl2-C20 branched chain alcohol
emollient.
Preferred compositions of the present invention are as
follows:
A clear, sprayable, liquid artiperspirant composition, having
a viscosity of less than about 15 centistokes, comprising:
a. from about lOX to about 25X of a monohydric alcohol-sol-
uble antiperspirant salti
b. from about 3% to about 20% of a non-volatile emollient
ester selected from the group consisting of esters of
C2-C20 alcohols and benzoic acid. esters of C2-C20
alcohols and C6-CI6 fa'~y acids, and mixtures thereof,
W O 91tl8586 PCT/~iS91/026X6
2~82823
.
having a solubility parameter of from about 7 to about
10;
c. trom 0% to about 8X of a propylene glycol ether of
a C~-C22 fatty alcohol;
d. from 0X to about 20~ of a volatile silicone emollient;
e. 'rom 0~O to about 3X of a pH buffer;
f. from 0~ to about 4% of a mixture of a dimethicone
copolyol in a suitable solvent therefor;
~. ,^nom abou~ ~vO ~o about lO~o of water; and
h. r`rom about 5c~v to about 65iV of a monohydric alcohol
solvent.
i~ore sDecific embodiments of such comoositions are AS
follows:
A clear, sprayable, liquid antiperspirant solution, having a
viscosity of less than about 15 centistokes, comprising:
a. from about 14% to about 16% of a monohydr k
alcohol-soluble antiperspirant salt, which is preferably an
ethanol-soluble aluminum sesquichlorohydrate antiperspirant
salt;
b. from about 3% to about 7YO of a non-volatile emollient
ester selected from the group consisting of esters of C2-C20
alcohols and benzoic acid, esters of C2-C20 alcohols and
C6-Cl~ fatty acids, and mixtures thereof, having a solubility
parameter of from about 7 to about 10, which is preferably
Cl2-Cls alcohols benzoate;
c. from about 3% to about 6X of a propylene glycol ether
of a C,-C22 fatty alcohol, which is preferably PPG-3 myristyl
ether,
d. from about 2% to about 3% of a pH buffer, which is
preferably urea;
e. from about 2% to about 4% of a mixture of a dimethicone
copolyol and a suitable solvent therefor, which is preferably
a mixture of D4 cyclomethicone and dimethicone copolyol at a
ratio of about 88:12;
f. from about 7~O to about 10X of water; and
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9. from about 50X to about 65X of a monohydric alcohol
solvent, which is preferably ethanol.
A clear, sprayable, liquid antiperspirant composition, having
a viscosity of less than about 15 centistokes, comprising:
a. from about 14X to about 16X of a monohydric
alcohol-soluble antiperspirant salt which is preferably an
ethanol-soluble sesquichlorohydrate antiperspirant salt;
b. C,om about 3X to about 8% of a non-volatile emollient
ei~er se7~cted rrom the group consisting of esters of C~-~20
iO il.o~ols and benzoic acid~ esters of C2-C20 alcohols anà
C8-CI6 fatty acids, and mixtures thereof, having a solubility
parameter of from about 7 to about 10~ which is prererabty
C~ 2-C1S alcohols benzoate;
c. from about 3% to about 6X of a propylene glycol ether
of a C~-C22 fatty alcohol, which is preferably PPG-3 myristyl
ether;
d. from about 2% to about 3% of a pH buffer, which is
preferably urea;
e. from about 7% to about 10% of water; and
f. from about SOX to about 65% of a monohydric alcohol
soluble solvent, which is preferably ethanol.
A clear, sprayable, liquid antiperspirant solution, having a
viscosity of less than about 15 centistokes, comprising:
a. from about 18% to about 24% of a monohydric
alcohol-soluble antiperspirant salt, which is preferably an
ethanol-soluble aluminum chlorohydrex antiperspirant salt;
b~ from about lOX to about 20X of a non-volatile emollient
ester selected from the group consisting of esters of C2-C20
alcohols and benzoic acid, esters of C2-C20 alcohols and
C6-C~6 fatty acids, and mixtures thereof, having a solubility
?arameter of from about 7 to about 10, which is preferably
selected from the group consisting of C12-C15 alcohols
benzoate, isopropyl myristate, and mixtures thereof;
c. from about 5% to about 15X of a volatile silicone
WO 91/18586 PCr/l~S9~/02686
` 2~82823
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emollient, which is Dreferably selected from the group
consisting of ~4-D5 cyclomethicone, pnenethyl pentamethyl
disiloxane, dimethicone t`luids haYin~ Yiscosities of less
than about 1 c~ntisto.k~, an~ m"ix;u,^-s ;nar o,`;
S d. from about 2X to about 3~ of ~ater; and
e. from about 5C`fo to abo~ 0 o,^ a ",oi,o,lvdnic alcoilol
solvent, which is prefor~bly eth~nol.
A clear, spr~ b1~
~laving a ~ijcosity ~ s~ J:
a. ~ro~ about iiV~ t.;~
soluble antipersp" a"; sa~ h,ch is pre,era~l~ an
ethanol-soluble sesquichi~cn~!drate antl~rsnirant salt;
b. from about 8æ to abou~ ' o~ ~ nQ~-volatile omolllon~
ester selected from the group consisting Ot esters of C2-C20
alcohols and benzoic acid, esters of C2-C20 alcohols and
C6-Cl6 fatty acids, and mixtures thereof, htving a solubility
parameter of from about 7 to about 10, which is preferably
selected from the group consisting of Cl2-Cls alcohols
benzoate, isopropyl myristate, and mixtures thereof;
c. from about 3% to about 6% of a propylene glycol ether
of a C,-C22 fatty alcohol, which is preferably PP~-3 myristyl
ether;
d. from about 2X to about 3X of a pH buffer, which is
preferably urea;
e. from about 4% to about S~ of a volatile silicone
emollient, which is preferably elected from the group
consisting of D4-D5 cyclomethicone, phenethyl pentamethyl
disiloxane, dimethicone fluids having viscosities of less
than about 1 centistoke, and mixtures thereof;
f. from about 2X to about 3~ of water; and
9. from about 50% to about 65~o of a monohydric alcohol
solvent, which is preferably ethanol.
Another preferred executiQn hereof is 2s follows:
A clear, sprayable, liquia antiperspiranl composition, having
a viscosity of less than about 5 centistokes, comprising:
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2~2823
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a. from about 14% to about 16~ of a monohydric alcohol-sol-
uble antiperspirant salt;
b. from about O.S% to about ô-,O o~ ~ non-volati7e emollient
ester selected '~rom the 91OUp cons~s~ing o; eit~r^s o;
C2-C20 alcohols and C~-C~ fatty acids, and mixtures
thereof, having a jolubi,i~j pai~al"ct2r of fro.., abo~t 7
to about 10;
c. from about lC~. to about 1~, 0~ ~ ~;^Ae~ ~ ene ~1 ~/Cel ether
of a C~-C22 rat~y alcoho~;
d. from about 12~ to laCU- ~`.5 '~ ~ `.0` ~il ' ``~iCOIl~
emollient;
e. from about 2X to about 6~ o~ ;~ C~ Drancnea cnair
alcohol emollient;
f. from about 0.25% to about 1~ of a non-volatile
dimethicone fluid having a viscosity of about 2 to about
20 centistokes;
9. from about 2% to about 3% water; and
h. from about 457O to about 55% of a monohydric alcohol
solvent.
An e5pecially preferred embodiment of a composition as
described immediately above is provided when:
a. the monohydric alcoho7-so7uble antiperspirant salt
comprises an ethanol-soluble sesquichlorohydrate anti-
perspirant salt;
b. the non-volatile emollient est~r is selected from the
group consisting of ethyl myristate, isopropyl myris-
tate, and mixtures thereof;
c. the propylene glycol ether is PPG-3 myristyl ether;
d. the volatile silicone emollient ;s selected from the
group consisting of cyclomethicone, phenethyl penta-
methyl disiloxane, and dimethicone fluids having vis-
cosities of less than about 1 centistoke, and mixtures
thereof;
e. the Cl2-C20 branched chain alcohol emollient comprises
from about 2X to about 6X isocetyl alcohol;
WO 91/18586 PCr/US91/02686
2082~23
- 8 -
f. the non-volatile dimethicone fluid has a viscosity of
about 2 to about 10 centistokes; and
9. the monohydric alcohol solvent is ethanol.
mleSe lat~er compositions are particularly advantageous in
that they can provide good product aesthetics and in-use charac-
te,is~ics, i"cluding antiperspirant efficacy and minimal skin
irritatioi~ i thout the necessity for a pH buffer.
~TATl'D ~ESC~PTION OF T~ INY~NTION
,"a ajsai,~,al as ~el, as optional components of the presen.
ccr,lpos: o!lS ~re aescribed below.
,dntt~-sDi,2nt ma~eri~l
A critical component of the present compositions is an
antiDerspirant material that is soluble and which remains soluble
in ethanol or another suitable monohydric alcohol solvent.
Solubilization of the antiperspirant material allows for the
formulation of the present clear antiperspirant solutions.
A variety of publications disclose antiperspirant actives
which are soluble in non-aqueous solvents, typically monohydric
alcohols (e.g., ethanol). U.S. Patent 3,873,686, Beekman, issued
March 25, 1975, (incorporated herein by reference) provides a
useful summary of work in this area. The following publications
relate to antiperspirant actives soluble in non-aqueous solvents
and/or processes for making such actives: U.S. Patent 3,359,169,
Slater et al., issued December 19, 1967; U.S. Patent 3,420,932,
Jones et al., issued January 7, 1969; U.S. Patent 3,507,896,
Jon~s et al., issued April 21, 1970; U.S. Patent 3,523,130, Jones
et al., issued August 4, 1970; U.S. Patent 3,555,146, Jones et
al., issued January 12, 1971; U.S. Patent 3,876,758, Beekman,
issued April 8, 1975; Great Britain Patent Specifications
1,159,685 and 1,159,686, both published July 30, 1969, Armour
Pharmaceutical Company; and European Published Patent Application,
7,191, published January 23, 1980, Unilever Limited.
U.S. Patent 2,890,987, Hilfer, issued June 16, 1959,
describes the preparation of relatively dilute solutions of
astringent aluminum compounds in propylene glycol having
WO 91/18586 Pcr/us91/026X6
` 2~82823
g
relatlvely high water content. U.S. Patent 4,137,306, Rubino et
al., issued January 30, 1979, describes anhydrous propylene glycol
solutlons of alcohol so1uble astringent basic aluminum compounds.
Any aluminum astringent antiperspirant salt or aluminum
and/o, -irccnium astringent complex that is soluble, and which
remains soluble in the present alcohol solvent can be used herein.
Sal.s usai^ul as astringent antiperspirant salts or as components
o~ as-~,^insa,l~ complPxes include aluminum hal;des, aluminum
hydroxyh~lides, zirconyl oxyhalides, zirconyl hydroxyhalides, and
mix~ure~ o,` .hese salt matérials.
Aluminum salts of this tvpe include aluminum chloride and the
alu",i" m ~,~y~no:~,nha1ides ha~ing the ceneral formula Al2(0H)xQy XH~0
wher~ ~ is chloride, bromide, or iodide (preferably chloride); x
is from about 2 to about 5, and x ~ y - about 6, and x and y do
not need to be integers; and where x is from about 1 to about 6
Aluminum salts of this type can be prepared in the manner
described more fully in U.S. Patent 3,887,692, Gilman, issued June
3, 1975, and U.S. Patent 3,904,741, Jones and Rubino, issued
September 9, 19~5, incorporated herein by reference.
The zirconium compounds which may be used in the present
invention include both zirconium oxy salts and zirconium hydroxy
salts, also ref~rred to as the zirconyl salts and zirconyl hydroxy
salts. These compounds may be represented by the following
general empirical formula:
7rO(O~) 2 -nzBz
wherein z may vary from about 0.9 to about 2 and need not be an
integer; n is the valence of B; 2-nz is greater than or equal to
0; and 3 may be selected from the group consisting of halides
(preferably chloride), nitrate, sulfamate, sulfate, and mixtures
thereof. Although only zirconium compounds are exemplified in
this specification, it will be understood that other Group IYB
metal compounds, including hafnium~ could be used in the present
invention.
As ~ith the basic aluminum co..pounds, it will be understood
that the above formula is greatly simplified and is intended to
W o 91/18586 PCI/~S91/(~2~Xfi
~ o ~ 2 ~
- 10 -
represent and include compounds ha~inA. co^-Air.a~ed ~n~'er ~ou~
water in various quantities, as well aS oo'\n~ers~ mix~ures an~
complexes of the above. As will b~.? S~? ?n ``''~ '.? Ii~O~- m ?r~
the zirconium hydroxy salcs ac~ually r?oneseni: a rance o,^
compounds haYing vario~s ~ou~s ?~
from about l.l to only sligh;i~ ~-^`?1'??` `` l;?n i) ~-,'OI!~S ?~?~`
. motecule.
S~er~?l ~yp~?s ~, ~n ~
antiperspirant salts are IcnQWn in ne ~s. -,~r ?~ -?. .i
lO Patent 3~92,~3, Lu~dd2,, e; i,~ `s.u u n~.m~
discloses complexes of aluminum, ~irconium~ ~nd amino ac~as sucn
as glvcines~ Comolexes sich ~ ? i ~ ''? . `
al. patent and other slmllan c.,.,-~ s ;~ O,l'~ 'i;,.:,- ; ~.;~^i~
ZAG complexes are chemically analy~able for the oresence of
aluminum, zirconium, and chlorine~ .AG com~1exes usePul herein
are identified by the specification of both the molar ratio of
aluminum to zirconium (hereinafter "Al:Zr~ ratio) and the molar
ratio of total metal to chlorine (hereinafter ~Metal:Cl~ ratio)~
ZAG complexes useful herein have an Al Zr ratio of from about 1.67
to about 12.5 and a Metal:Cl ratio of from about 0.73 to about
1.93.
Preferred ZAG complexes are fGr,.,ed by
(A) co-dissolving in water
(l) one part Al2(0H)s-mQm~ wherein Q is an anion
selected from the group consisting of chloride, bromide~
and iodide; and m is from about O.g to about 2~0;
(2) x parts Zr0(0H)2~aQa~n~20, where q is chloride,
bromide, or iodide; a is from about l to about 2i n is
from about 1 to about 8; and x is from about 0.16 to
about 1.2;
(3) p parts neutral amino acid selec~ed from .he group
consisting of glycine, dl-tryptophane, dl-~-phenyl-
alanine, dl-valine, dl--.ethionine~ and 3-alanine. and
where p is from about 0.06 to about 0.53:
(B) codrying the resultant ", Ature to a ,^niable ,clid; and
WO 91/18586 PCT/US91/02686
` 2~)g2823
^ 11 -
(C) reducing the resultant dried inorganic-organic antiper-
spirant complex to a par~icula~e fo.~.
A preferred aluminum compound ror preparation of such ZAG
type complexes is aluminum chlo~ydroxi e o~ e empii~ical formu,a
Al2(0H)sCl-2H20. Preferred zirconium comDounds for preparation of
such ZAG-type compleA2s a, 2 ~i. COnj, `'~d, oxychloride having tha
empirical formula 2rOtOH)C1-3H~0 and the 7irconyl hydroxyhalides
of the Pmpirical formula 7rO OH`) ~ H~? wher~in ~ is from
about i.5 to abou~ l.oi, i,d ; ,s r^~v, a~c;;. ` ~~ abou' ~ ~'~
preferred amino acid ror !i~ mi,~ pe CO~ p'~xej i i
glycine of the formula CH2,H~ OH~ ja~s o such ~mino aclos
can also be employed in tne antiDersDirant co~Diexes. iee U.S.
Patent 4,017,599, Rubino issued ~pril 12. ~977. incorDorated
herein by reference.
A wide variety of other types of antiperspirant complexes are
also known in the art. For exa~ple, U.S. Patent 3,903,258,
Siegal, issued September 2, 1975, discloses a zirconium aluminum
complex prepared by reacting zirconyl chloride with aluminu~
hydroxide and aluminum chlorhydroxide. U.S. Patent 3,979,510,
Rubino, issued September 7, 1976, discloses an antiperspirant
complex formed from certain aluminum compounds, certain zirconium
compounds, and certain complex aluminum buffers. U.S. Patent
3,981,896, issued September -21, 1976~ discloses an antiperspirant
complex prepared from an aluminum polyol compound, a zirconium
compound and an organic buffer. U.S. Patent 3,970,748, Mecca,
issued July 20, 1976S discloses an ~luminum chlorhydroxy glycinate
complex of the appropriate general formula [Al~(OH)~Cl][H2CNH2-
COOH]. All of these patents are incorporated by reference herein.
Of all of the above types of antiperspirant actives,
preferred compounds include the 5/6 basic aluminum salts of the
empirical formula Al2(0H)5Cl-2H20: mixtures of AlCl3-6H20 and
Al2(0H)sCl-2H20 with aluminum chloride to aluminum hydroxychloride
weight ratios of up to about 0.5i ZAG type complexes wherein the
zirconium salt is ZrO(OH)Cl-3H~O, tne aluminum salt is Al2(0H)sCl
2H20 or the aforementioned mixtures of AlCl3-6H20 and Al2(0H)sCl-
WO 91/18586 PCr/US91/026X6
20~23
2H20 wherein the total metal to chloride molar ratio in the
complex is less than about 1.25 and the Al:~r molar ratio is about
3 3, and the amino acid is glycine; and the ZAG-type complexes
wher?in the zirconium salt is 2rO(OH)2~aCla-nH20 wherein a is from
about 1.5 to about 1.87 and n is from about 1 to about ~, the
aluminum salt is Al2(0H)sCl-2H23, and the amino acid is glycine.
The most preferred antiperspirant actives useful in the
co,i,pos,~.a,.s of the present invention are antiperspirant actiYes
~ h enilallced erl~icacy due to ;mproved molecular d;stribution.
~lumir,u:, cnlorhydroxide salts, zirconyl hydroxvchloride salts~ and
mixtures thereof having improved molecular distributions are
known~ having been disclosed~ for example in the following
documents~ all incorporated by reference herein: U.S. Patent
4,359,456, Gosling et al., issued November 16, 1982; European
Published Patent Application 6,739, Unilever Ltd., published
January 9, 1980; European Published Patent Application, 183,171,
Armour Pharmaceutical Company, published June 4, 1986; Brittsh
Patent Specification 2,048,229, The Gillette Company, published
December 10, 1980; European Published Patent Application 191,628,
Unilever PLC, published August 20, 1986; and British Patent
Specification 2,144,992, The Gillette Company, published March 20,
19~5.
The improved molecular distribution is determined by the
known analysis method called gel permeation chromatography. This
2S analysis method is described, for example, in several of the
above-incorporated patent specifications as well as in European
Published Patent Application 7,191, Unilever Ltd., published
January 23j 1980, the disclosures of which are incorporated
herein. It is preferred for purposes of the present invention
that the antiperspirant actives utilized have enhanced efficacy
due to improved molecular distribution with a ratio of peak 4 to
peak 3 greater than about 0.1:1 as determined by gel permeation
chromatography. This ratio, as is recognized by one skilled in
the art, relates to the relative area under those two peaks as
3s measured by the gel permeation chromatography analysis method.
WO 91/18586 PCr/US91/02686
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Highly desirable antiperspirant salts for use herein are
selected from the group consisting of aluminum sesquichloro-
hydrate, aluminum sesquichlorohydrex PEG ~a coordination complex
of aluminum ,esquiehlorohydrate and PEG-4, in which some of the
S ~.~ater molecules normally coordinated to the metal have been
displaceà by ~he PEG-4), aluminum sesquichlorohydrex PG (a
coord~n~tion complex of aluminum sesquichlorohydrate and propylene
gly~ol in ~.a~,~h some of th~ ~ater molecules normally coordinated
to the metal have been displaced by the propylene glycol), alumi-
num chloro,l~d,ex~ in the form of aluminu~ chlorohydrex PEG (acoordination complex of aluminum chlorohydrate and PEG-4 in which
some of the ~ater molecules normally coordinated to the metal have
been displaced hy the PEG-4), and most preferably aluminum chloro-
hydrex PG, sold under the names Rehydrol II~ or Activated Rehydrol
15 II~, by Reheis Chemical Company (coordination complex of aluminum
chlorohydrate and propylene glycol in ~hich some of the water
molecùles normally coordinated to the metal have been displaced by
propylene glycol so that about 25% of the complex comprises
propylene glycol). Mixtures of these antiperspirant materials may
also be utilized. The coordination complex antiperspirant mate-
rials tend to have a higher pH, and are therefore less irritating
to skin.
All of these materials are particularly safe for use in
spray-on compositions. The most preferred antiperspirant salts for
use herein are aluminum sesquichlorohydrate and Rehydrol IlX or
Activated Rehydrol IIS.
U.S. Patent 4,053,581, Pader et al., issued October 11, 1977;
U.S. Patent 4,065,564, Miles Jr. et al., issued December 27, 1977;
and U.S. Patent 4,073,880, Pader et al., issued February 14, 1978i
all disclose formulations for pump-spray or roll-on antiperspir-
ants comprising alcohol-soluble aluminum chlorohydroxide antiper-
spirant complexes, an alcohol vehicle, and volatile and/or non-
volatile silicone materials.
The antiperspirant salt is present in the liquid antiper-
spirant compositions of the present invention at a level of from
W O 91/18586 rcT/~s9l/o26~6
20~2823 - 14
about 10X to about 25X. If an aluminum sesquichlorohydrate
antiperspirant salt is used in ~ Q Pr-~Sanr COmDOS;~;OnS, i. is
preferably present at from abou~ 1 , .o abolir lS~.. This ~.~eight
percentage is calculated cn an an"yd.o~ e:- S1`~ a3sis ,a,~-
clusive of complexing agents~. If one o-f ~he Rvllydrol~ anti-
perspirant salts ,s us~d ln 'ha pnes~ cv~avi~'v.,s,
preferably present at from about l^~ .o l~CU,. ^1~ of the com~o-
sition. This hi~her le~.~el ~- ma~ar ~`~ s ~ a~ n^. -lls
antip~ pi~a~ a~?lal ~v~ "~ "~
active but a comple.~ing a~en~ ~ o~ ~ s
Solv~ent for th~_~nu~;5~1.a". Sa,t
The antiperspirant saits o~ t.~ r^-sen. ,nv^ntion ar~ soiu-
bilized in a solvent. suitaDle snl~ents include monohvdric
alcohols, especially C2-C4 monohydric al cohols. Tne pr ferred
solvent for use herein is ethanol. A small amount of water is
also necessary ln the prcsent compositions to solubilize the
antiperspirant material. The present compositions will comprise
from about 2% to about 10% of water.
The solvent is present in the compositions of the present
invention at a level at least sufficient~ to solubilize the
antipersp;rant salt. It is desirable to keep the leYel of
monohydric alcohol solvent in the DreSent comDositions as ,ow as
possible to allow for the incorporation of as much emollient
materials as possible. This results in a product with improved
in-use characteristics. Gener lly, the alcohol solvent is pres~nt
in the compositions at a level of from about 45~ to about 654~
preferably from about 45~. to about 5~/40, more preferably from about
45% to about 55X.
Emollients
The present antiperspirant composition also comprise non-
volatile emollient esters, and optionally, propylene glycol ethers
of C,-C22 fatty alcohols, Ci2-C20 branched chain alcohols, and
volatile silicone emollients. It is these components that are
primarily responsible for the desirable product aesthetics and
in-use characteristics of the oresent compositions. For example~
these components provide the smooth, clean, dry, non-sticky feel
W O 91/18586 rCT/~S91/026~6
2~2823
- 15 -
upon application to the skin. The non-volatile emollient mate-
rials are also responsible for lessoning he amount of residue on
skin after dry down. ThesP emo71ient components ~re present in
the antiperspirant compositions a~ ma~;",i.ec levels ;o proviaa
thesê benefits.
Part of the emollient ma~nia, oi` .b- prQsent coi"~osl,ionj
comprises a non-volatile emollient ~s`-~. This material may
compris~ C2-C20 alcohol ~ 5
alcohol ben~oates; es~ers, ~ ans, or~ ;a~raes~ars oi C2-C~
alcohols and C6-C1~ fatt~ ~ci~ SOplOp~` se~aca.~,
di;sopropyl adipate, laury7 laota.~ y, ~yrista.e, isopropy~
myristate, myristyl myristate~ an~l ~antaer~hrit~l t~traDelaroo-
nate); and mixturPs thereof~ The ?roferrod ^f theso non-volatlla
emollient materials are ethyl myristate, isopropyl myristate,
Cl~-C~s alcohols benzoate, and mixtures thereof.
In order to maintain the clear stable solution of the present
antiperspirant compositions, the non-volatile emollient ester must
be of a certain polarity, i.e., it must have a solubility
parameter (units equal (cal/cm3)1/2) in the range of from about 7
to about 10.
The solubility parameter is defined in the Polymer Handbook
3rd Ed. (John Wiley and Sons~ New York), ~ BrandruD and E.H~
Immergut, Chapter YII, PP. 519-559, as the square root of the
cohesive energy density and describes the attractive strength
between molecules of the material. Solubility parameters may be
determined by measurement, correlations with other physical
properties, or indirect measurement. The solubility parameters
for the present emollient materials were determined by surface
tension measurement as outlined in Vaughan, C.D., J. Soc. Cosmet.
Chem., 36, 319-333, 1985.
Generally, these compositions comprise from about 0.5% to
about 20~ of the non-volatile emollient ester materials.
The antiperspirant compositions of the present invention also
preferably comprises volatile silicone emollient materials. These
materials have solubility parameters of trom about 5.5 to about 8.
W O 91/18586 PCT/US91/02686
20~823 - 16 -
Various types of silicone materials have been disclosed for
use in various forms of antiperspirant compositions. For example,
U.S. Patent 4,784,844, Thimineur et al., issued November 15, 1988;
U.S. Pa-ent 4,499,069, Kra~ton, issued February 12, 1985; U.S.
Patent 4~268,499, Keil, issued May 19, 1981; U.S~ Patent
4,264~8O~ Cal7ingham et al., issued April 28, 1981; U.S. Patent
4,053~31~ P~der et al., ;ssued October 11, 1977, U.S. Patent
4,~,~;5 "6~, ,lilej, Jr et al " issued December 27, 19i7; U.S.
Pa~en~ 4~ Pader et al., issued February 14~ lg~8; U.S.
r~ n~ 5~, Soldati, issued ~une 16. 1987; U.S. Patent
4,55~,22~, ;ogel, issued December 17, 1985; U.S. Patent ~,i35,382,
~hin et al ~ issued March 6~ 1984; EuroDean Patent Office
Applicaticn 343!Q~3, published ~ovember 29, 1989; Great Britain
Patent Application 1,S36,222, published December 20, 1978; Great
Britain Patent Application 2,018,590, published October 24, 1979;
and Japanese Published Patent Application 59-152,318, published
August 31, 1984.
The volatile silicone emollient materials of the present
compositions generally have a viscosity of from about 0.65
centistokes to about 10 centistokes. Certain volatile silicone
materials, such as cyclic polydimethylsiloxanes containing from
about 3 to about 7 s~licon atcms r~re useful herein. A description
of volatile silicones is found in Todd and Byers, ~Volatile
Silicone Fluids for Cosmetics", Cosmetics and Toi1etries, 91:27-32
(197~), incorporated herein by reference. Other volatile
silicones useful herein are tau~ht in U.S. Patent 4,874,868,
Bolich, ~r., issued October 17, 1989, incorporated by reference
herein. A volatile silicone that may be used in the present
compositions, which is covered in that patent, is phenethyl
pentamethyl disiloxane.
The present compositions comprise up to about 20X of such
volatile silicone emollient materials. The preferred volatile
silicone emollient materials o,^ the present invention are D4-D5
cyclomethicones, phenethyl penta methy7 disiloxane, dimethicone
fluids having viscosities of less than about 1 centistoke, and
mixtures thereof.
WO 91/18586 PCr/US91/02686
- 17 - 2082823
The compositions also may comprise Cl2-C20 branched chain
alcohols as preferred emollients hereof, and mixtures thereof.
These C~2-C20 branched chain alcohols must be liquid at room
tempera~uret and are preferably liquid at O'C, and should have
solu~ilit~ sarameters of from about 7 to about 10, and viscosities
or from abou~ 1~ to about 50 centistokes at 2S'C. The preferred
alcch~ th~ C~s branched chain alcohol, isocetyl alcohol.
O~,len C~-C~ ~,^anched chain alcohols include isododecanol,
isos~eal~, dlcohol, etc. The degree of branching can vary widely,
~o la~ ai .h~^ a~o~e viscosity and solubility parameters are met.
Ihe branched chain alcoho7 component hereof can be conveniently
made bv condensation of straight chain alcohols in al~aline medium
^ccording 'Q the rs3ction referred to in the art as the Guerbet
isomerization reaction (alternately, Guerbet condensation) the
branched chain alcohols in the reaction product thereof being
referred to as Guerbet reaction branched alcohols. This reaction
which w~ll typically produce a mixture of branched chain isomer
alcohols in the reaction product is well known in the art and is
described by Edman and Lowden, in Drug Cosmet . Ind., Vol. 93, p
631, Nov. 1963, by Pruett, Young, Duncan, and Mozeleski in
European Patent Application 88-306359, July 12, 1988, and by
Yeibel and Nielsen in ~Mechanism of the Guerbet Reaction~, Tetra-
hedron, 23 (4), pp 1723-33. Suitable C12-C20 branched chain
alcohols, including isocetyl alcohol, are also widely commercially
available, e.g., ~enkel, Inc. (Teaneck, NJ).
The compositions of the present invention also comprise up to
about 15%, preferably from about 3X to about 8X, more preferably
from about 3% to about 6X, of polypropylene glycol (nPPG~) ethers
of C~-C22 (preferably C~D_C20) fatty alcohols as emollients.
Examples of such materials include PPG-2 myristyl ether, PPG-4
lauryl ether, PPG-10 cetyl ether, PPG-3 myristyl ether, PPG-11
stearyl ether, PPG-15 stearyl ether and mixtures thereof. Addi-
tional examples are found in CTFd Cosmetic Ingredient Dictionary,
Third Edition (Extrin et al., Editors; The Cosmetic, Toiletry and
Fragrance Association, Inc., 1982). pages 252-260 and 494-500, the
W O 91/18586 PCT/~S91/026X6
2~8'~823
- 18 -
disclosures of which are incorporated by reference herein. The
preferred of such emollients for use in .ne ~resen; c~"aositions
is PPG-3 myristyl ether.
Buffer
The compositions of the present invention maV also comorise a
pH buffer to raise the low ?~ inhcrcn~ ,n~;ùe,,ulra~ ;i~ S~-
tions. Such a buffer may comprise '!re~. e'` .`? bU'A^~rir~ a~.en-~
described in U.S. Patent 1,lS
19~5; U.S~ Patent ~,3~o,u~ oehi ~ a,.. ,ss~u i.~;~s~
and U.S. l,518,582, Schamcer el a,.~ ?~
diethanolamine, triethanoiamil,e, g~yc,~ 3 ~i~a~`lO~Il.e~,`yiâ
all of which are incorporated herein ae re`er~nce.
The buffer, if used in the presont so~Qositlnn~ prosen~
at up to about 3%, preferably from about 2~ to abou; 3~ The
preferred buffer for use herein is urea.
Detackifier
The present compositions may also comprise a detackifying
agent to further improYe the cosmetic in-use benefits of the
present compositions. The detackifier may comprise a mixture of a
dimethicone copolyol in a suitable volatile solvent therefor.
Useful solvent materials comprise the volatile silicone materials
described supra. A preferred material tnat can be used for this
purpose in the present compositions is a material sold under the
trade name Q2-3225C Formulation Aid~ by Dow Corning. It comprises
a mixture of D~ cylcomethicone and dimethicone copolyol (polymer
of dimethyl siloxane with polyoxyethylene and/or polyoxypropylene
side chains) at a ratio of about 88:12. If this material is
included in the compositions of the present invention it is at a
level of up to about 4%, preferably from about 2% to about 4%.
Other preferred materials that can be included and which can
be used as detackifiers include non-volatile dimethicone fluids,
preferably with viscosities less than about 20 centistokes and
also preferably at least about 2 centistokes, more preferably from
about 2 to about 10 centistokes, most preferably from about 5 to
about 10 centistokes. Mixtures of such fluids can ~e used.
W O 91/18586 PCT/~S91/0268~
2~2~23
Non-volatile dimethicone will preferably be present in the compo-
sitions hereof at a level of from C~ to about 2~ by weisht.
Typically, when utilized as a detac~irian, t,Se ccmpositions will
comprise from about 0.1~ to abou~ '~O~ p~ `er~b,y ,^.^om ~ o~
to about 1~ of the non-volatile dimethicone.
ODtional components
The compositions of the pr~sent comcosition may also comprise
a number of optional components to orovide e~smetic or aest~etic
benefi-s. For example, pr 2ser'.'a~`~`i'es~ i~od~ e`~ `U;~
anti-microbials or bactericidei, pe ~;.m~i~ ;a'or n~ ea'i
dyes may be used.
These optional components mus~ ~e .nosen s~ as no~ .o
interfere with the antiperspirant ef;icacy and the composition
stability. These optional components are generally present in the
compositions of the present invention at a level of from about
0.01% to about lOX.
Product$
The present compositions are preferably in the form of a
low-viscosity non-aerosol pump spray. However, the present
invention is applicable to other liquid antiperspirant product
types, such as aerosol or roll-on product types. Products
formulated as aerosols will also comprise a propellant material.
Any of the commonly used propellants in the antiperspirancy art
are suitable. Products formulated as roll-ons will also comprise
a thickening agent to raise the viscosity of the composition.
Suitable thickening agents include carboxymethyl cellulose, clay
thickeners, colloidal silica, and Microthene9 beads, manufactured
by U~S~I~ Chemicals, having a mean particle diameter of less than
about 20 microns~
Methods of Manufacture
The antiperspirant compositions of the present invention may
be manufactured using methods known in the art. In making the
compositions, the antiperspirant salt is first solubilized in the
monohydric alcohol solvent, and a small amount of water (no more
than 5% water, by weight of the antiperspirant composition) to
WO 91/18586 PCl`/US91/02686
2~82823
- 20 -
form a clear solution. The remaining components are then added to
the composition using conventional formulation methods.
~ethod for Proventing PersDiration and Malodor
-M~Q ^ asent invent,Qn ~lso provides methods for treating or
preventing perspiration and malodor associated with human underarm
perspiration. These methods comprise applying a safe and effec-
tive amount of the liquid antiperspirant compositions of the
pr~S?n~ i, ve,ltion to the s'~in in the axillary area of a human.
The ~rm a ~s3te and effective a~ount~ as used herein, i5 an
:~c~ Q ;~ q~ S o, s~s~2nt~ r~duci~g
tha ?rod~ctiQn of perspiration which ultimately generates the
,nalc~ e~c'~d 'hroush ,^^r~ation af pungen~ ,`atty aciGs "ihile
being sar`e t`or .human use at a reasonaDle risk/benetit ratio.
The l;quid antiperspirant compositions of the present
invention provide excellent cosmetic attributes both on
application and throughout use. They are non-sticky, non-greasy,
and quick drying. In addition, the present compositions leave no
white, chalky residue on skin upon dry down.
The following examples illustrate the present invention. It
will be appreciated that other modifications of the present
invention within the skill of those in the antiperspirant formu-
lation art can be undertaken without departing from the spirit and
scope of this invention.
All parts, percentages, and ratios herein are by weight
unless otherwise specified.
ExamDle I
The following is a clear, liquid, spray-on antiperspirant
composition representative of the present invention.
ComDonent Weight %
Rehydrol II~ Antiperspirant Activel 20.0
Isopropyl Myristate 9.0
C,2-C1s Alcohols Benzoate2 9.0
D4 Cyclomethicone 9.5
~ater 2.5
Ethanol 50 0
w o 91/18~86 PCTt~S91/02686
- 21 - 2 0~2 823
Perfume 0.8
Aluminum chlorohydrate and propylene glycol coordination
complex available from Reheis Chemical Company
2 AVaillbl~ under t~l2 trade name FinsolY TN9 from Finetex,
Inc.
The c~myssl'l.cn is prepared as follows. The antiperspirant
activo is first premixed with at least half of the ethanol. The
main m~ hen pr?plred by adding to the premix the remaining
ethano " ~"~ i;UpiA~?;'~ m,~rista~e, the C12-C1s alcohols benzoate.
th~ ! C`!Ci~ /ll` Jil.~ 'Ui~
The r~sul~ing antiperspirant composition provides excellent
antipersDirancy .of;icacy ~.~ith good product aesthetics and in use
charactQristics. The composition also remains stable over time
and broad ranges of physical conditions, especially ambient
temperatures.
Exam~le~ 1l
The following is a clear liquid spray-on antiperspirant
composition representative of the present invention.
ComDonent ~eiqht X
Rehydrol II9 Antiperspirant Active1~o 0
C12-C15 Alcohols Benzoate2 13.75
D4 Cyclomethicone 13.75
Water 2.5
Ethanol 50 0
Perfume 0.8
Aluminum chlorohydrate and propylene glycol coordination
complex available from Reheis Chemical Company
2 Available under the trade name Finsolv TN~ from Finetex,
Inc.
The composition is prepared as follows. The antiperspirant
active is first premixed with at least half of the ethanol. The
main mix is then prepared by adding to the premix the remaining
ethanol, the C12-C1s alcohols benzoate, the D4 cyclomethicone, and
the perfume.
3S
W O 91/18586 PCT/~S9l/n26X6
2082823
- 22 -
The resulting antiperspirant composition provides excellent
antiperspirancy efficacy with good product ~esthetics anG in-uso
characteristics. The composition also re"ains s-able oYe~A ~lme
and broad ranges of physica~ ~ondi~icns, esp~c,aii; ~im~.eA
temperatures.
EXamQ1 e~
The following is a clear liquid s~-?~v-on 3n~ a;, A~n~.
composition representative of the ~res~n` in~ mnA~on.
ComDonent ;~;i~!
I0 Aluminum Sesquichlotohydrate ~ .
SD A1coho1 ~0 S~
DR0 Water 9 -i
C 12 - C 1 ~ Alcohols Benzoate~ .l n
3225 Formulation Aid2 3 0
I5 Urea 2.S
PPG-3 Myristyl Ether 5.0
Perfume 0.8
Available under the trade name Finsolv TN from
Finetex, Inc.
2 A mixture of D4 cyclomethicone and dimethicone copolyol
(88:12 ratio) available from Dow Corning
This composition is prepared as ;ol70ws. An aluminum
sesquichlorohydrate (ASQCH) premix is prepared by combining the
ASQCH, at least half of the ethanol and water. The main mix is
then prepared by adding to the ASQCH premix the remaining ethanol,
the CI2-Cl, alcohols benzoate, the 3225 formulation aid, the urea,
the PPG-3 myristyl ether, and the perfume.
The resulting antiperspirant composition provides excellent
antiperspirancy efficacy with good product aesthetics and in-use
characteristics. The composition also remains stable over time
and broad ranges of physical conditions, especially ambient
temperatures.
Example IY
The following is a liquia antiperspirant composition
representative of the present invention.
WO 91/18586 PC-r/l S91/02686
` ` 2~828~3
- 23 -
ComDonent ~eiqht
Aluminum Sesquichlorohydrate 15.0
SD Alcohol 40 5C.0
DR0 Water ~ ,
C12-C~5 Alcohols Benzoate1 4.0
3225 Formulation Aid2 ~ o
Urea 2.5
PPG-3 Myristyl Ether ~o
Perfume 0~8
1 Available under the trad~ na"le Ein~o'i ~ Cre,,
Finetex, Inc.
2 A mixture of D4 cyclometnicone an~ ui"e~li;one c~a,~o.
(88:12 ratio) available from Dow Corning
This composition is prepared as follows. An aluminum
sesquichlorohydrate (ASQCH) premix is prepared by combining the
ASQCH, at least half of the ethanol and water~ The main mix is
then prepared by adding to the ASQCH premix the remaining ethanol,
the C12-C15 alcohols benzoate, the 3225 formulation aid, the urea,
the PPG-3 myristyl ether, and the perfume.
The resulting antiperspirant composition provides excellent
antiperspirancy efficacy with good product aesthetics and in-use
characteristics. The composition also remains stable oYer time
and broad ranges of physical conditions, especially ambient
temperatures.
ExamDle Y
The following is a liquid antiperspirant composition
representative of the present invention.
ComDonent Weiqht
Aluminum Sesquichlorohydrate 15.0
SD Alcohol 40 60.0
DR0 Water 3.0
Isopropyl Myristate 10.7
D4 Cyclomethicone 8.0
Urea 2.5
Perfume 0.8
W O 91/18586 PCT/~S91/02686
` 2~2823
- 24 -
This composition is prepared as follows. An aluminum
sesquichlorQh~dr~tQ (ASQCH) premix is prepared by combining the
ASQC~, at le1s~ hal, o, the ethanol and water~ The main mix is
th~-n ,..`?a~ y ~d'.ng; ~ ~e ~SCC!` pr~Qmix the rQmaining ethanol,
isopropyl myristatP, the 04 cyclomethicone, the urea, and the
p~r~
he r-sulting antiperspirant composition provides excellent
~n~ ~arsa~:n;~ ~f ,ccc~ / `h ~3dd product aesthetics and in~use
T'~ ".~^;t~ lso rc~ ns st~bl~ o~er ti~
t Qi;~
,`h~ `ollc:~ing is a 'iqui~ antiper~pirant composition
representative of the pres~Qnt invention~
lj Comoonen~ Wei~ht X
Aluminum Sesquichlorohydrate 15.0
SD Alcohol 40 60.0
DR0 Water 3.0
C~ 2 -Cls Alcohols Benzoatel 6.7
D4 Cyclomethicone 8.0
Urea 2.5
PP~3 Myrtstyl Ether 4.0
Perfume 0.8
1 Available under the trade name Finsolv TN~ from
Finetex, Tnc.
This composition is prepared as follows. An aluminum
sesquichlorohydrate (ASQCH) premix is prepared by combining the
ASQCH, at least half of the ethanol and water. The main mix is
then prepared by adding to the AS~CH premix the remaining ethanol,
the Cl2-Cls alcohols benzoate~ the D4 cyclomethicone, the urea,
the PPG-3 myristyl ether, and the perfume.
The resulting antiperspirant composition provides excellent
antiperspirancy efficacy with qood product aesthetics and in-use
character,s,lcs. The composition also remains stable over time
3~
WO 91/18~86 PCr/US91/026X6
2~2823
- 25 -
and broad ranges of physical conditions, especially ambient
temperatures~
Exam~le VII
~r"e 0, ,c;ii~,g iS 3 l-,quid antiperspirant composition
r~presentatiYe of the present invention.
Col~oonell~ Weiqht X
Al umi nllm 5~cru ~ chlorohydr~te 15.0
S~ Alc~ '` 60.0
~0 ;ia~ 9.2
C~2~ n~ 7.0
Urea 2.5
PP~-3 ~r~,st~l ~ther ~s
PerfumQ 0~8
1 Available under the trade name Finsolv TN~ from
Finetex, Inc.
This composition is prepared as follows. An aluminum
sesquichlorohydrate (ASQC~) premix is prepared by combining the
ASQCH, at least half of the ethanol and water. The main mix is
then prepared by adding to the ASQCH premix the remaining ethanol,
the C12-C1s alcohols benzoate, the urea, the PPG-3 myristyl ether,
and the perfume.
The resulting antiperspirant composition provides excellent
antiperspirancy efficacy with good product aesthetics and in-use
characteristics. The composition also remains stable over time
and broad ranqes of physical conditions, especially ambient
temperatures.
ExamPle VIII
The following is a liquid antiperspirant composition
representative of the present invention.
ComDonent ~eight %
Aluminum Sesquichlorohydrate 15.0
SD Alcohol 40 60.0
DR0 ~ater 2.5
Isopropyl ~yristate 9.2
D4 Cyclomethicone 4.0
WO 91/18586 P(~/l~S91/02686
` ` '2082~23
- 26 -
PPG-3 Myristyl Ether 8.5
Perfume ~
This composition is prepared as ,`ol`,ows. An al~minum
sesquichlorohydrate (ASQCH) preinix is ,'?`~ U 3V eO~ ln,n, :`_
ASQCH, at least half of the ethanol and water. The main mi~ ic
then prepar~d by adding to the AS4C.1 premia 'na r~m.a n~n~ a:nan~'.
the isopropyl myristate, the D4 cyclomet~icon~ the P~ 3 mYris~yl
ether, and the perfume.
The ,esu1ting antiperspl, ant aa mr~s'~ r~ ia ~
I0 antiperspirancy efficacy ~ich gooc ~i`QU~a ~ n.
characteristics. The composition also rem~in~ a~ie o~:er ~m~
and broad ranges of physicai condit7dns~ eso~ciai ~ aln~i~r
temperatures.
ExamDle IX
The following is a 1iquid antiperspirant composition
representative of the present invention.
Compone~ ~eiqht X
Aluminum Sesquichlorohydrate 15.0
SD Alcohol 40 50.0
D4 Cyclomethicone 13.8
PPG-3 Myristyl Ether 12.0
Isocetyl Alcohol 4.
Water 2.6
Ethyl Myristate I.0
Dimethicone fluid (5 centistoke) 0.5
Perfume 1.0
This composition is prepared as follows. An aluminum
sesquichlorohydrate (ASQCH) premix is prepared by combining the
ASQCH, at lease half of the ethanol and water. The main mix is
then prepared by adding to the ASQCH premix the remaining ethanol,
the D4 cyclomethicone, the PPG-3 myristyl ether, the isocetyl
alcohol, the ethyl myristate, the non-Yolatile dimethicone fluid,
and the perfume.
The resulting antiperspirant composition has relatively low
ethanol content and provides excellent antiperspirant efficacy
W O 91/18586 PCT/~S91/02686
2~2823
- 27 -
with good product aesthetics and in-use charactèristics without
the need for the incorporation of a pH buf~er. The composi.ion
also remains stable over time and broad ranges of physical
conditions, especially temperature.
WHAT IS CLAIMED IS:
