ENSEMBLE DE VISSAGE POUR VISSER DES BOUCHONS D'OBTURATION DANS DES SERINGUES

SCREWING ASSEMBLY FOR SCREWING CLOSING PLUGS ONTO SYRINGES

Abrégé français

Un bouchon de fermeture est vissé sur lextrémité ouverte filetée dune seringue par un ensemble de vissage muni dune poche destinée à recevoir le bouchon de fermeture à partir dune trémie dans laquelle sont logés une pluralité de bouchons de fermeture, un dispositif de support de la seringue et un dispositif dactionnement pour déplacer la poche et le dispositif de support lun par rapport à lautre avec un mouvement de roto-translation autour et le long dun axe longitudinal de la seringue afin de visser le bouchon de fermeture sur lextrémité ouverte de la seringue elle-même.

Abrégé anglais

A closing plug is screwed onto the threaded open end of a syringe by a screwing assembly provided with a pocket adapted to receive the closing plug from a hopper which houses in its inside a plurality of closing plugs, a support device of the syringe, and an actuating device for moving the pocket and the support device with respect to each other with a roto-translating movement about and along a longitudinal axis of the syringe so as to screw the closing plug onto the open end of the syringe itself.

Revendications

8
THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE PROPERTY OR
PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. Screwing assembly for screwing closing plugs onto syringes, each syringe
presenting a
longitudinal axis and comprising a cylinder provided with a threaded open end
and a plunger
engaged in a sliding manner in the cylinder itself; the screwing assembly
being characterized in
that it includes: a fixed support frame closed on a top end by a hopper, the
hopper housing in its
inside a plurality of closing plugs, the hopper including a plate having an
outlet for the closing
plugs from the hopper itself; a pocket mounted on a bottom surface of the
plate, positioned
under the plate, and arranged inside the fixed support frame, the pocket
suited to receive and
hold the closing plug fed each time through said outlet; a support device for
supporting the
syringe; actuating means for moving the pocket and the support device with
respect to one
another with a roto-translating movement around and along said longitudinal
axis, so as to
screw the closing plug onto said open end; and a shock absorber device
positioned under the
plate and interposed between the plate and the support frame, so as to allow
the pocket to
move with respect to the syringe parallel to said longitudinal axis while the
pocket remains
positioned under the plate, and while the closing plug is being screwed onto
the open end of the
syringe itself while the pocket remains positioned under the plate.
2. Screwing assembly according to claim 1 and comprising, furthermore, a
first stop device,
which is mobile inside the hopper from and to an operating position, in which
the first stop
device prevents a first closing plug from reaching said outlet.
3. Screwing assembly according to claim 2 and comprising, furthermore, a
second stop
device, which is arranged behind the first stop device, and is mobile inside
the hopper from and
to an operating position, in which the second stop device is arranged so as to
separate the first
closing plug from the remaining closing plugs contained in the hopper.
4. Screwing assembly according to claim 1, wherein the plate comprises a
vibrating plate
defining a support plane, which is inclined with respect to a horizontal
reference plane.
5. Screwing assembly according to claim 4, wherein the hopper is delimited
by a lateral
wall defining a conveying channel of the closing plugs along the vibrating
plate; the conveying

9
channel comprising an outlet section connected to said outlet and an inlet
section converging
towards the outlet section itself.
6. Screwing assembly according to claim 5 and comprising, furthermore, a
first stop device,
which is mobile inside the hopper from and to an operating position, in which
the first stop
device prevents the closing plugs from being transferred from the outlet
section to said outlet,
and a second stop device, which is mobile inside the hopper from and to an
operating position,
in which the second stop device prevents the closing plugs from being
transferred from the inlet
section to the outlet section.
7. Screwing assembly according to claim 1 and comprising, furthermore, an
electric motor
for moving the pocket around said longitudinal axis.
8. Screwing assembly according to claim 1, wherein the pocket is delimited
by a bottom
wall, which is perpendicular to said longitudinal axis, and by a lateral wall,
which is inclined with
respect to the bottom wall itself at an angle different from 90°.
9. Screwing assembly according to claim 8, wherein the lateral wall of the
pocket presents
a quadrilateral shape.
10. Screwing assembly according to claim 1, wherein the plate includes four
vertices; and
wherein the shock absorber device includes four elastic elements, each elastic
element
mounted between the support frame and the plate at a respective vertex of the
plate.

Description

CA 02808755 2013-03-06
1
SCREWING ASSEMBLY FOR SCREWING CLOSING PLUGS ONTO
SYRINGES
The present invention relates to a screwing
assembly for screwing closing plugs onto syringes.
In the injectable pharmaceutical product
preparation, it is known to make a machine comprising at
least one store for a plurality of containers (bags,
syringes and bottles, in the case in point); at least
one dosing station for the preparation of pharmaceutical
product obtained by feeding into a syringe a
pharmaceutical taken from a bottle and diluent taken
from a bag; and a gripping and conveying device for
transferring the containers between the store and the
dosing station.
The syringe comprises a containment cylinder, a
plunger engaged in sliding manner in the containment
cylinder and a needle snap-locked onto an open end of
the containment cylinder itself.
After having prepared the pharmaceutical product in
the syringe, the needle is removed from the syringe and
the open end is sealed by means of the closing plug in
order to allow medical personnel to safely handle the
syringe itself.
Because the closing plug is normally snap-locked on
the open end of the syringe, the known machines for the
preparation of pharmaceutical products of the type
described above have some drawbacks mainly deriving from

CA 02808755 2013-03-06
2
the fact that the closing plug and the syringe are moved
against each other with a relatively high coupling
force, which may damage both the closing plug and the
open end of the containment cylinder, thus preventing
the subsequent assembly of a new needle.
Furthermore, the known machines for the preparation
of pharmaceutical products of the type described above
do not allow the use of threaded closing plugs and thus
have a relatively low flexibility of use.
It is the object of the present invention to
provide a screwing assembly for screwing closing plugs
on syringes which is free from the above-described
drawbacks and which is simple and cost-effective to
implement.
According to the present invention, a screwing
assembly for screwing closing plugs onto syringes is
provided as disclosed in the appended claims.
The present invention will now be described with
reference to the accompanying drawings, which illustrate
a non-limitative embodiment thereof, in which:
figure 1 is a perspective diagrammatic view, with
parts removed for clarity, of a preferred embodiment of
the screwing assembly of the present invention;
figure 2 is a diagrammatic plan view of a detail in
figure 1; and
figure 3 is an exploded perspective view of the
detail in figure 2.
With reference to figures 1, 2, and 3, numeral 1

CA 02808755 2013-03-06
3
indicates as a whole a screwing assembly for screwing
closing plugs 2 of substantially quadrilateral shape
onto syringes 3 of known type, each of which has a given
longitudinal axis 4 and comprises a containment cylinder
5, which is provided with a externally threaded open end
6, and is slidingly engaged by a plunger 7.
In the case in point, the plugs 2 are designed so
as to be absolutely tamperproof during handling of the
syringes 3 containing the pharmaceutical product to be
administered to patients.
The screwing assembly 1 comprises a boxed frame 8
closed on the top by a containment hopper 9 for a
plurality of plugs 2 arranged within the hopper 9 with
their concavities facing upwards.
The hopper 9 comprises a vibrating plate 10, which
has a substantially rectangular shape, defines a support
plane P for the plugs 2 inclined according to a given
angle with respect to a substantially horizontal
reference plane, and has an outlet hole 11, which is
obtained through a lower end of the plate 10, and has a
longitudinal axis 12 substantially perpendicular to the
plane P itself.
The plate 10 is slidingly coupled to the frame 8
with the interposition of a shock absorber device 13 to
perform rectilinear movements in a direction 14
substantially parallel to axis 12 with respect to the
frame 8, and is additionally coupled in sliding manner
to the frame 8 to move with respect to the frame 8 and

CA 02808755 2013-03-06
4
under the bias of an actuating device 15, with a
reciprocating rectilinear motion in a substantially
horizontal direction 16 transversal to direction 14.
Device 13 comprises, in the case in point, four
elastic elements 17 mounted between frame 8 and plate 10
at the vertexes of the plate 10 itself; and the device
comprises an electromagnetic actuator 18, which is
fixed within the frame 8 parallel to direction 16, and
has an outlet rod 19 connected to a coupling bracket 20
10 protruding downwards from the plate 10.
The hopper 9 is limited on the side by a hollow
plate 21, which is fork-shaped, is fixed onto the plate
10 to define an advancement channel 22 of the plugs 2
along the plane P and towards the hole 11, and is shaped
15 so as to divide the channel 22 into a lower
substantially rectilinear outlet section 22a connected
to the hole 11 and an upper inlet section 22b converging
towards section 22a.
Channel 22 cooperates with a first stop device 23
comprising an actuating cylinder 24, which is mounted
inside the plate 21 parallel to direction 16, and has an
output rod 25 mobile between a rest position, in which
the rod 25 is substantially contained in the plate 21,
and an operating position, in which the rod 25 protrudes
into the section 22a to prevent the plugs 2 from
reaching the inside of the section 22a itself.
The channel 22 further cooperates with a second
stop device 26, comprising an actuating cylinder 27,

CA 02808755 2013-03-06
. .
which is mounted inside the plate 21 parallel to
direction 16, and has an output rod 28 mobile between a
rest position, in which the rod 28 is substantially
contained in the plate 21, and an operating position, in
5 which the rod 28 protrudes into the section 22a
downstream of the rod 25 to prevent the plugs 2 from
reaching the hole 11.
With regards to this, it is worth specifying that
the movement of the rods 25 and 28 in their operating
positions defines a compartment adapted to accommodate a
single plug 2 therein.
The screwing assembly 1 further comprises a support
device 29 of a syringe 3, e.g. a robotized arm, adapted
to keep the syringe 3 in position coaxial to the axis
12, and a support device 30 adapted to receive the plug
2 fed each time through the hole 11.
The device 30 comprises a pocket 31, which is
mounted inside the frame 8, under the plate 10, and in
position facing the hole 11, is limited by a bottom wall
32, which has a quadrilateral shape substantially
corresponding to the shape of the plugs 2, and which
extends perpendicular to direction 14, and is further
limited by a quadrilateral side wall 33, which extends
about axis 12, and is inclined according to an angle
other than 90 with respect to the wall 32 itself.
The pocket 31 is mounted on the free end of the
outlet shaft 34 of an electric motor 35, which is
mounted within the frame 8 parallel to direction 14, is

CA 02808755 2013-03-06
six
6
fixed to the hopper 9 under the plate 10, is adapted to
move the pocket 31, with respect to the plate 10 itself,
about axis 12, and is torque-controlled so as to allow
the correct screwing of the plugs 2 onto the respective
syringes 3.
The shape of the pocket 31 and of the lower outlet
section 22a of the channel 22 allows the plugs 2 to drop
through the hole 11 so as to be aligned with, and
correctly inserted in the pocket 31 itself during the
rotation about the axis 12.
The operation of screwing assembly I will now be
described with reference to figures 1, 2 and 3 starting
from an instant in which:
the syringe 3 is moved by the device 29 to a
position coaxial to axis 12;
the stop devices 23, 26 are arranged in their
operating positions; and
the outlet section 22a of the channel 22 is empty.
Device 23 is firstly moved to its rest position to
allow a plug 2 to drop into the section 22a and is then
moved again to its operating position to prevent other
plugs 2 from dropping into the section 22a itself.
The device 26 is thus moved to the rest position
thereof to allow the considered plug 2 to reach the hole
11 and fall into the pocket 31.
At this point, the syringe 3 is lowered by the
device 29 so as to allow the open end 6 of the syringe 3
to engage the plug 2 and to move the assembly defined by

CA 02808755 2013-03-06
7
the hopper 9 and by the pocket 31 against the bias of
the elastic elements 17 of the shock absorbers device
13.
Finally, the pocket 31 and thus the plug 2 are
moved about the axis 12 by the actuation of the electric
motor 35 and along the axis 12 by the bias of the
elastic element 17 of the shock absorber device 13. In
other words, the pocket 31 and the plug 2 are moved with
roto-translating movement about and along the mentioned
axis 12 in order to screw the plug 2 onto the open end 6
of the syringe 3.
With regards to the above, it is worth noting that
the pharmaceutical product contained in the syringe 3
does not exit from the end 6 due to the surface tension
and the capillarity of the cylinder 5 at the open end 6
itself.

Dessin représentatif