Note : Les descriptions sont présentées dans la langue officielle dans laquelle elles ont été soumises.
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PC7~79RCT
DEVICE FOR CLOSING T~E CONTAINMENT WELL 0~ A BLOOD
CENTRIFUGATIO~ CELL IN A CENTRIFUGAL MAC~iINE
The invention relate~ to a duvlce for closing the
contalnment well of a blood eentrifugatlon cell in a centrif-
ugal maehine.
Blood eentrifugatlon is well known for separation of its
fraetion component~ sueh as plasma, white cells, red eells,
eto. The proee~s ls condueted ln blood centrifugation cells
having a rigid rotatable container and a stationary ~oint
connected to ducts for the ln~low of the blood and for the
lo outflow of the re~peetlve ~eparated fractlon~. In order to
perform the eentrlfugation, the eell ls lnserted in a well
and the contalner is locked onto a rotatable chuck at the
ba~u of a eentrlfugal maehine. The stationary ~oint is kept
in position by a device whlch clo~es the inlet of the well
and whlch aleo conflnea the ffpace in~lde the w~ll, lsolating
it to avold the e~cape Or blood if the eell ~hould break.
The most advaneed well elo6ure deviees of the prior art are
those which leave the duets eonnected to the stationary ~oint
outside the well, thus ensurlng an easy assembly and optimum
sealing; however, it 1~ lmpossible to integrally clean the
well, particular lts lnlet.
An object of the present invention i~ to provide a
deviee for elo~ing the eontainment well of a blood centrifu-
gation cell ln a centrifugal machine which allows lntegral
cleaning of the entire well, particularly the inlet and the
immediately adjacent regions.
Another ob~eet of the invention iA to provide a device
which proteets the integrity of the stationary joint of the
cell and of the duets connected thereto during thç opening
and closure operations and furthermore helps assure safety
during the proeedure.
The proposed objeet~ are achieved by a devlce f or
closing the inlet of a containment wull of a blood centrlfu-
gation cell in the body of a cuntrifugation machine eharac-
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terlzed in that lt comprlses: a contalnment well for the blood
centrlfugatlon cell; a plate supported at one end of the lnlet of
the contalnment well and rotatable about the horlzontal axls; sald
plate havlng a palr of parallel plns extendlng perpendlcularly from
the surface thereof, each pln havlng a rotatlonal axls; a palr of
half-llds whlch are each plvotally supported at one end thereof by
one of sald plns for rotatlon about the respectlve axes of the plns
ln a plane perpendlcular to the plns, and the half-llds havlng
matable lnner edges; means for blaslng the half-llds normally lnto
a mutually spread-apart, plvoted open conflguratlon; and means for
locklng sald half-llds lnto a closure posltlon, the means for
locklng lncludlng pro~ectlons on the half-llds rlgldly assoclated
wlth each half-lld as symmetrlcal halves for formlng a cyllndrlcal
portlon and an upper conlcal portlon held by an actuatlon knob
carrled on the contalnment well for movement, the actuatlon knob
havlng a correspondlng recess so that when the half-llds are
rotated downwardly agalnst the lnlet and wlth sald half-llds
plvoted together, thereby closlng the lnlet of the contalnment
well.
Further characterlstlcs and advantages wlll become
apparent from the descrlptlon of a preferred but not excluslve
embodlment of the lnventlon, lllustrated only by way of non-
llmltatlve example ln the accompanylng drawlngs, whereln:
Flgure 1 ls a plan vlew of the lnventlon, wlth one half-
lld ln closed posltlon and the other half-lld arranged so as to
adhere to the lnlet of the well but ln open posltlon;
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Figure 2 is a partially sectional side view of the
invention;
Figure 3 is a sectional view taken along the plane
III-III of Figure 1;
Figure 4 is a perspective view of a mounting plate
with its related supports.
With reference to the above figures, particularly
Figure 2, a containment well 1, is included within a centrifugal
machine, for enclosing a blood centrifugation cell 2, (shown in
phantom lines) in which a container 2a is rotated by being
connected to a rotating chuck (not shown). A stationary joint
2b is provided with couplings 2c for conveyance ducts for the
inlet of blood and for the extraction of the separated
fractions.
Referring also to Figure 1, the device for closing the
well comprises a pair of half-lids 3 and 4 which have mating
inner edges and which can be both spread apart and rotated from
one end. The half-lids are pivotable in a divaricated manner at
one end, respectively on two parallel axes provided by pins 5
and 6 which extend generally perpendicularly from
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a plate 7. The plate 7 is provided with two horizontal end
pivots 7a and 7b which engage corresponding holes provided in
two supports 8a and 8b which are secured by screws 9 to the
body at one end of the well 1. The plate 7 facilitates the
rotation of the half-lids upwardly for an open configuration
and downwardly in a position to close the well.
The method of pivoting of the half-lids 3 and 4 on the
respective axes is described in more detail by referring also
to Figures 3 and 4. It can be seen that the rotational axis
of half-lid 4 is provided by the upper pin 6a and which
extends from the upper side face of the plate 7 and rotatably
engages a hole 4a provided within the half-lid 4, while the
lower pin 6b engages a corresponding hole provided in a plate
10. A screw lOa secures the plate 10 to the half-lid 4 to
pivotably secure the half-lid to the plate 7. Half-lid 3 is
similarly secured to the plate on pin 5.
The half-lids 3 and 4 are provided with elastic means
adapted to mutually space them by rotation about the pins 5
and 6. A small round-headed cylinder 11, is slidably
accommodated in a hole 12 provided within the half-lid 4 and
is pushed by a spring 13 against the facing surface of the
half-lid 3, which is provided, in the region of contact, with
the metallic abutment lla.
In operation, the two half-lids 3 and 4 are always
intrinsically mutually spread apart in a divaricated manner
by the action of the cylinder 11, on abutment lla. This
occurs regardless of the orientation of the plate 7 about its
axis of rotation. Only the voluntary action of an operator
can move the half-lids mutually closer until they are in
contact, overcoming the action of the spring 13 within the
cylinder 11. Thus, when it is necessary to access the inside
of the well 1 to insert a cell 2, the half-lids 3 and 4 are
rotated into the completely raised position and are naturally
divaricated, as mentioned. It should be noted that in this
position of the half-lids, the well and its adjacent regions
are completely available for integral cleaning. Once the
cell 2 is inserted, the half-lids are pivoted downwardly by
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the rotatability of the plate 7 and are lowered in the spread
open condition so as to not compromise or interfere with the
stationary joint 2b or with the related couplings 2c of the
ducts. When the half-lids make contact with the inlet of the
well, the operator approaches the half-lids 3 and 4 to move
the mating inner edges into mutual contact and locks them in
this "closure position". The locking means is shown particu-
larly in Figures 2 and 3, and comprise two projections each
of which is rigidly associated with each half-lid. The
projections are symmetrical halves which form a cylindrical
portion 14 and an integral upper conical portion 15 formed
when the half-lids are in the closure position. (The
projection associated with the half-lid 4 is visible in
Figure 1.) The half-lids 3 and 4 are locked together by the
engagement of the projections 14 and 15 within a correspond-
ingly shaped conical recess 15a and cylindrical recess 14a in
an actuation knob 16. The actuation knob 16 is fixed at the
upper end of a vertically oriented rod 17. The rod is
slidably and rotatably supported within a cylindrical sleeve
18 which is rigidly associated with the body of the well 1.
The rod includes a threaded portion 19 adapted to engage with
female thread 18a which is rigidly associated with the sleeve
18. A spring 20 is interposed between the bottom of the
sleeve 18 and the threaded portion 19 of the rod 17. A cam
21 is also rigidly associated with the rod 17 for actuating
a sensor 22 which is used in conjunction with circuitry to
enable safe operation of the centrifugal machine only when
the half-lids are in the closure position.
In order to lock the half-lids 3 and 4 in closure
position, the operator, starting from the condition illus-
trated in Figure 2, pushes the knob 16 downward, overcoming
the action of the spring 20, until the threaded portion 19
makes contact with the female thread 18a; at this point the
knob is rotated to engage the threads which further engages
the portions 14a and 15a of knob 16 to lock over and around
portion 14 and 15 of the projections. After a few turns of
the threads, the base of the knob 16 makes contact with a
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base plane 23. At this point, the cam 21 has moved to
actuate the sensor 22 which enables the start-up of the
centrifugage, since the half-lids have been completely closed
into the closure position.
At the end of the centrifugation, the operator unscrews
the knob 16. The cam 21 immediately moves the sensor 22,
which operates with the circuitry to provide a suitable
indicator to prevent the release of the half-lids while the
cell has not completely stopped rotation. Premature opening
of the half-lids is further avoided because even during the
unscrewing operation, the cylindrical portion 14a of the
recess remains in contact with the cylindrical portion 14 of
the projection, and therefore the half-lids cannot abandon
their mutual contact. In the time used by the operator to
disengage the threads, the cell stops its motion, after which
the knob 16 can be raised, allowing the half-lids to spread
apart in the divaricated manner, and the half-lids can be
rotated upwardly to open the well.
The described invention is susceptible to numerous
modifications and variations, all of which are within the
scope of the inventive concept: all the details may further-
more be replaced with other technically equivalent elements.
In the practical embodiment of the invention, the
materials employed, as well as the shapes and dimensions, may
be any according to the requirements.
