COMPOSES A BASE D'ACIDES NUCLEIQUES POUR L'INHIBITION DE L'EXPRESSION GENIQUE ET UTILISATION DESDITS COMPOSES

NUCLEIC ACID COMPOUNDS FOR INHIBITING GENE EXPRESSION AND USES THEREOF

Abrégé anglais

The present disclosure provides RNA molecules, for example, meroduplex
ribonucleic
acid molecules (mdRNA), and blunt ended double-stranded ribonucleic acid
molecules capable
of decreasing or silencing expression of a target gene. An mdRNA of this
disclosure comprises
at least three strands that combine to form at least two non-overlapping
double-stranded regions
separated by a nick or gap wherein one strand is complementary to a target
mRNA. Also
provided are methods of decreasing expression of a target gene in a cell or in
a subject to treat a
disease or condition associated with the target gene.

Revendications

CLAIMS:
1. An RNA molecule that down regulates the expression of a target mRNA,
the RNA molecules comprising a first strand that is complementary to a human
target
mRNA and a second strand complementary to the first strand, wherein the first
strand and
second strands can anneal to form a double-stranded region having from about
15 base
pairs to about 40 base pairs.
2. The RNA molecule of claim 1 wherein the first strand is from 19 to 24
nucleotides in length or from 25 to 29 nucleotides in length and is
complementary to a
human target gene selected from the group consisting of tumor necrosis factor
(TNF),
vascular endothelial growth factor (VEGF), vascular endothelial growth factor
receptor
(VEGFR), epidermal growth factor receptor (EGFR), erythroblastic leukemia
viral
oncogene homolog (ERBB), platelet derived growth factor (PDGF), platelet
derived
growth factor receptor (PDGFR), breakpoint cluster region (BCR)-abelson murine
leukemia viral oncogene homolog (ABL), steroid-5-alpha-reductase, alpha
polypeptide 1
(SRD5A1), steroid-5-alpha-reductase, alpha polypeptide 2 (SRD5A2),
phosphoinositide-
3-kinase, catalytic (PIK3C), mitogen-activated protein kinase (MAPK), p38 MAPK
family, hypoxia-inducible factor 1 alpha (HIF1A), protein kinase N3 (PKN3),
interleukin
17A (IL17A), interleukin 6(IL6), interleukin 18 (IL18), tumor necrosis factor
(ligand)
superfamily member 13b (TNFSF13B), mitogen-activated protein kinase 1(MAPK1),
v-
raf-1 murine leukemia viral oncogene homolog 1(RAF1), v-AKT murine thymoma
viral
oncogene (AKT), FK506 binding protein 12-rapamycin associated protein
1(FRAP1),
mitogen-activated protein kinase 2 (MAPK2), cyclin-dependent kinase 2 (CDK2),
ATP-
binding cassette, subfamily B, member 1(ABCB1), B-cell CLL/lymphoma 2 (BCL2),
angiopoietin 2 (ANGPT2), checkpoint kinase 1 homolog (CHEKI), insulin-like
growth
factor 1 receptor (IGF1R), signal transducer and activator of transcription 3
(STAT3),
matrix metalloproteinase (MMP), folate hydrolase (prostate-specific membrane
antigen) 1
(FOLH1), v-myc myelocytomatosis viral oncogene homolog (avian) (MYC),
telomerase
RNA component (TERC), telomerase reverse transcriptase (TERT), protein kinase
C,
alpha (PRKCA), RAS viral (v-ras) oncogene homolog (RAS), chemokine (C-X-C
motif)
ligand or receptor (CXC), Wingless-Type MMTV (Murine Mammary Tumor Virus)
742

Integration Site (WNT), toll-like receptor (TLR), Fc fragment of IgE, low
affinity II,
receptor for (CD23) (FCER2), FOS gene, (FOS, FOSB, FOSL1, OR FOSL2),
hydroxysteroid (11-beta) dehydrogenase (HSD11B1), JUN gene (cJUN, JUNB, or
JUND),
thymidine phosphorylase (TYMP), early growth response (EGR), zeste homolog 2
(EZH2), cyclin D1 (CCND1), Fas (TNF receptor superfamily, member 6) (FAS),
proliferating cell nuclear antigen (PCNA), fibroblast growth factor 2 (FGF2),
tumor
growth factor-beta (TGF-.beta.), tumor growth factor-beta receptor (TGF-
.beta.R), tumor-
associated calcium signal transducer 1(TACSTD1), Mucin 1(MUC1), protein
tyrosine
phosphatase, non-receptor-11 (Noonan Syndrome 1) (PTPN11), neuregulin 1(NRG1),
membrane metallo-endopeptidase (MME), CD19 molecule (CD19), CD40 molecule, TNF
receptor superfamily member 5(CD40), apolipoprotein B (including Ag(x)
antigen)
(ApoB), synuclein, alpha (non A4 component of amyloid precursor) (SNCA),
silent
mating type information regulation 2 homolog (SIRT2), histone deacetylase
(HDAC),
membrane-spanning 4-domains, subfamily A, member 1(MS4A1), CD22 molecule
(CD22), diacylglycerol o-acyltransferase 1(DGAT1), diacylglycerol o-
acyltransferase 2
(DGAT2), CD3 molecule (CD3), proprotein convertase subtilisin-like kexin type
9
(PCSK9), MET (Mesenchymal epithelial transition factor) (c-Met proto-
oncogene),
catenin (cadherin-associated protein) (beta-catenin) (CTNNB1), inhition of DNA
binding
proteins (Inhibition of Differentiation Proteins, Dominant Negative Helix-Loop-
Helix
Protein) (ID), protein tyrosine phosphatase, non-receptor type 1(PTPN1), tie-1
(TIE1;
tyrosine kinase with immunoglobulin and EGF factor homology domains 1), tek
tyrosine
kinase (TEK), fibroblast growth factor receptor (FGFR), mitogen-activated
protein kinase
3 (MAPK3), survivin (BIRC5), and polo-like kinase family genes (PLK1).
3. The RNA molecule of claim 1 wherein the RNA molecule has at least one
blunt end.
4. The RNA molecule of claim 1 wherein the RNA molecule has at least one
3'-overhang.
5. The RNA molecule of claim 1 further comprising at least one acyclic
nucleomonomer.
743

6. The RNA molecule of claim 5 wherein the acyclic nucleomonomer is
selected from the group consisting of
<IMG>
wherein,
R is selected from the group consisting of hydrogen, a methyl group, C(1-
10) alkyl, cholesterol, naturally or non-naturally occurring amino acid,
sugar, vitamin,
flurophore, polyamine and fatty acid.
7. The RNA molecule of claim 6 wherein at least one acyclic nucleomonomer
is linked to the blunt end of the RNA molecule.
8. The RNA molecule of claim 6 at least one acyclic nucleomonomer is in the
double-stranded region of the RNA molecule.
9. A method for reducing the expression of a human target gene, comprising
administering an RNA molecule of claim 1 to a cell expressing the target gene,
wherein
the RNA molecule reduces expression of the target gene in the cell.
10. The method according to claim 9 wherein the cell is a human cell.
744

11. A meroduplex ribonucleic acid (mdRNA) molecule that down regulates the
expression of a target mRNA, the mdRNA molecules comprising a first strand of
15 to 40
nucleotides in length that is complementary to a target mRNA and a second
strand and a
third strand that are each complementary to non-overlapping regions of the
first strand,
wherein the second strand and third strand can anneal with the first strand to
form at least
two double-stranded regions spaced apart by a nick or a gap.
12. The mdRNA molecule of claim 11 wherein the first strand is 15 to
25 nucleotides in length or 26 to 40 nucleotides in length.
13. The mdRNA molecule of claim 11 wherein the first strand is from 19 to 24
nucleotides in length or from 25 to 29 nucleotides in length and is
complementary to a
human target gene selected from the group consisting of tumor necrosis factor
(TNF),
vascular endothelial growth factor (VEGF), vascular endothelial growth factor
receptor
(VEGFR), epidermal growth factor receptor (EGFR), erythroblastic leukemia
viral
oncogene homolog (ERBB), platelet derived growth factor (PDGF), platelet
derived
growth factor receptor (PDGFR), breakpoint cluster region (BCR)-abelson murine
leukemia viral oncogene homolog (ABL), steroid-5-alpha-reductase, alpha
polypeptide 1
(SRD5A1), steroid-5-alpha-reductase, alpha polypeptide 2 (SRD5A2),
phosphoinositide-
3-kinase, catalytic (PIK3C), mitogen-activated protein kinase (MAPK), p38 MAPK
family, hypoxia-inducible factor 1 alpha (HIF1A), protein kinase N3 (PKN3),
interleukin
17A (IL17A), interleukin 6(IL6), interleukin 18 (IL18), tumor necrosis factor
(ligand)
superfamily member 13b (TNFSF13B), mitogen-activated protein kinase 1(MAPK1),
v-
raf-1 murine leukemia viral oncogene homolog 1(RAF1), v-AKT murine thymoma
viral
oncogene (AKT), FK506 binding protein 12-rapamycin associated protein
1(FRAP1),
mitogen-activated protein kinase 2 (MAPK2), cyclin-dependent kinase 2 (CDK2),
ATP-
binding cassette, subfamily B, member 1(ABCB1), B-cell CLL/lymphoma 2 (BCL2),
angiopoietin 2 (ANGPT2), checkpoint kinase 1 homolog (CHEK1), insulin-like
growth
factor 1 receptor (IGF1R), signal transducer and activator of transcription 3
(STAT3),
matrix metalloproteinase (MMP), folate hydrolase (prostate-specific membrane
antigen) 1
(FOLH1), v-myc myelocytomatosis viral oncogene homolog (avian) (MYC),
telomerase
RNA component (TERC), telomerase reverse transcriptase (TERT), protein kinase
C,
alpha (PRKCA), RAS viral (v-ras) oncogene homolog (RAS), chemokine (C-X-C
motif)
745

ligand or receptor (CXC), Wingless-Type MMTV (Murine Mammary Tumor Virus)
Integration Site (WNT), toll-like receptor (TLR), Fc fragment of IgE, low
affinity II,
receptor for (CD23) (FCER2), FOS gene, (FOS, FOSB, FOSL1, OR FOSL2),
hydroxysteroid (11-beta) dehydrogenase (HSD11B1), JUN gene (cJUN, JUNB, or
JUND),
thymidine phosphorylase (TYMP), early growth response (EGR), zeste homolog 2
(EZH2), cyclin D1 (CCND1), Fas (TNF receptor superfamily, member 6) (FAS),
proliferating cell nuclear antigen (PCNA), fibroblast growth factor 2 (FGF2),
tumor
growth factor-beta (TGF-.beta.), tumor growth factor-beta receptor (TGF-
.beta.R), tumor-
associated calcium signal transducer 1(TACSTD1), Mucin 1(MUC1), protein
tyrosine
phosphatase, non-receptor-11 (Noonan Syndrome 1) (PTPN11), neuregulin 1(NRG1),
membrane metallo-endopeptidase (MME), CD19 molecule (CD19), CD40 molecule, TNF
receptor superfamily member 5(CD40), apolipoprotein B (including Ag(x)
antigen)
(ApoB), synuclein, alpha (non A4 component of amyloid precursor) (SNCA),
silent
mating type information regulation 2 homolog (SIRT2), histone deacetylase
(HDAC),
membrane-spanning 4-domains, subfamily A, member 1(MS4A1), CD22 molecule
(CD22), diacylglycerol o-acyltransferase 1(DGAT1), diacylglycerol o-
acyltransferase 2
(DGAT2), CD3 molecule (CD3), proprotein convertase subtilisin-like kexin type
9
(PCSK9), MET (Mesenchymal epithelial transition factor) (c-Met proto-
oncogene),
catenin (cadherin-associated protein) (beta-catenin) (CTNNB1), inhition of DNA
binding
proteins (Inhibition of Differentiation Proteins, Dominant Negative Helix-Loop-
Helix
Protein) (ID), protein tyrosine phosphatase, non-receptor type 1(PTPN1), tie-1
(TIE1;
tyrosine kinase with immunoglobulin and EGF factor homology domains 1), tek
tyrosine
kinase (TEK), fibroblast growth factor receptor (FGFR), mitogen-activated
protein kinase
3 (MAPK3), survivin (BIRC5), and polo-like kinase family genes (PLK1).
14. The mdRNA molecule of claim 11 wherein the gap comprises from 1 to 10
unpaired nucleotides.
15. The mdRNA molecule of claim 11 wherein the mdRNA molecule has at
least one blunt end.
16. The mdRNA molecule of claim 11 wherein the mdRNA molecule has at
least one 3'-overhang comprising one to four nucleotides that are not part of
the gap.
746

17. The mdRNA molecule of claim 11 further comprising at least on acyclic
nucleomonomer.
18. The mdRNA molecule of claim 17 wherein the at least one acyclic
nucleomonomer selected from the group consisting of:
<IMG>
wherein,
R is selected from the group consisting of hydrogen, methyl group, C(1-10)
alkyl, cholesterol, naturally or non-naturally occurring amino acid, sugar,
vitamin, flurophore, polyamine and fatty acid.
19. The mdRNA molecule of claim 18 wherein at least one acyclic
nucleomonomer is linked to the blunt end of the mdRNA molecule.
20. The mdRNA molecule of claim 18 at least one acyclic nucleomonomer is
in one of the double-stranded regions of the mdRNA molecule.
747

21. A method for reducing the expression of a human target gene, comprising
administering an mdRNA molecule of claim 11 to a cell expressing the target
gene,
wherein the mdRNA molecule reduces expression of the target gene in the cell.
22. The method according to claim 21 wherein the cell is a human cell.
23. Use of an mdRNA molecule or dsRNA molecule as defined in any one of
the preceding claims for the manufacture of a medicament for use in the
therapy of cancer,
a metabolic disease or inflammatory disease.
748

Description

CA 02677068 2009-09-01
DEMANDES OU BREVETS VOLUMINEUX
LA PRESENTE PARTIE DE CETTE DEMANDE OU CE BREVETS
COMPREND PLUS D'UN TOME.
CECI EST LE TOME _16 DE _16
NOTE: Pour les tomes additionels, veillez contacter le Bureau Canadien des
Brevets.
JUMBO APPLICATIONS / PATENTS
THIS SECTION OF THE APPLICATION / PATENT CONTAINS MORE
THAN ONE VOLUME.
THIS IS VOLUME -16 OF 16
NOTE: For additional volumes please contact the Canadian Patent Office.

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 8
cuccgaagaa auaagaucct t 21
<210> 9
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 9
ggaucuuauu u 11
<210> 10
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 10
cuucggagtt 10
<210> 11
<211> 27
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 11
cauugucucc gaagaaauaa gauccuu 27
<210> 12
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 12
ggaucuua 8
<210> 13
<211> 17
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNAIRNA Molecule:
Synthetic oligonucleotide
741-3577

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 13
uuucuucgga gacaatg 17
<210> 14
<211> 16
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 14
uucuucggag acaatg 16
<210> 15
<211> 15
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 15
ucuucggaga caatg 15
<210> 16
<211> 14
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 16
cuucggagac aatg 14
<210> 17
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 17
uucggagaca atg 13
<210> 18
<211> 12
741-3578

CA 02677068 2009-09-01
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 18
ucggagacaatg 12
<210> 19
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 19
cggagacaat g 11
<210> 20
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 20
ggaucuuau 9
<210> 21
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<400> 21
ggaucuuauu 10
<210> 22
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
741-3579

CA 02677068 2009-09-01
<221> modified base
<222> (2)
<223> LNA-G
<400> 22
ggaucuuauu u 11
<210> 23
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 23
ggaucuuauu uc 12
<210> 24
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 24
cuacacaa 8
<210> 25
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (8)
<223> LNA-A
<400> 25
aucagcgauu utt 13
<210> 26
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-A
<400> 26
741-3580

CA 02677068 2009-09-01
ucagcgauuu tt 12
<210> 27
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-A
<400> 27
cagcgauuutt 11
<210> 28
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (5)
<223> LNA-A
<400> 28
agcgauuutt 10
<210> 29
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (4) <223> LNA-A
<400> 29
gcgauuutt 9
<210> 30
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222>(3)
<223> LNA-A
<400> 30
cgauuutt 8
<210> 31
<211> 7
741-3581

CA 02677068 2009-09-01
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-A
<400> 31
gauuutt 7
<210> 32
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 32
cuacacaaa 9
<210> 33
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 33
cuacacaaau 10
<210> 34
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 34
cuacacaaau c 11
<210> 35
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3582

CA 02677068 2009-09-01
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 35
cuacacaaau ca 12
<210> 36
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 36
cuacacaaau cag 13
<210> 37
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 37
cuacacaaau cage 14
<210> 38
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 38
ggaucuuauu ucu 13
<210> 39
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
741-3583

CA 02677068 2009-09-01
<400> 39
ggaucuuauu ucuu 14
<210> 40
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (8)
<223> LNA-A
<400> 40
ggaucuua 8
<210> 41
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (9)
<223> LNA-U
<400> 41
ggaucuuau 9
<210> 42
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<220>
<221> modified base
<222> (10)
<223> LNA-U
<400> 42
ggaucuuauu 10
<210> 43
<211> 11
741-3584

CA 02677068 2009-09-01
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<220>
<221> modified-base
<222> (11)
<223> LNA-U
<400> 43
ggaucuuauu u l1
<210> 44
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (12)
<223> LNA-C
<400> 44
ggaucuuauu uc 12
<210> 45
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (13)
<223> LNA-U
<400> 45
ggaucuuauu ucu 13
<210> 46
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
741-3585

CA 02677068 2009-09-01
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (14)
<223> LNA-U
<400> 46
ggaucuuauu ucuu 14
<210> 47
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (8)
<223> LNA-G
<400> 47
uuucuucgga gtt 13
<210> 48
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 48
uucuucggag tt 12
<210> 49
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-G
<400> 49
741-3586

CA 02677068 2009-09-01
ucuucggagtt II
<210> 50
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (5)
<223> LNA-G
<400> 50
cuucggagtt 10
<210> 51
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (4)
<223> LNA-G
<400> 51
uucggagtt 9
<210> 52
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-G
<400> 52
ucggagtt 8
<210> 53
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
741-3587

CA 02677068 2009-09-01
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<400> 53
cggagtt 7
<210> 54
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (1) <223> LNA-U
<220>
<221> modified base
<222> (8)
<223> LNA-G
<400> 54
uuucuucgga gtt 13
<210> 55
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 55
uucuucggagtt 12
<210> 56
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
741-3588

CA 02677068 2009-09-01
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (6)
<223> LNA-G
<400> 56
ucuucggagtt 11
<210> 57
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (1) <223> LNA-C
<220>
<221> modified base
<222> (5)
<223> LNA-G
<400> 57
cuucggagtt 10
<210> 58
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNAIRNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (1) <223> LNA-U
<220>
<221> modified-base
<222> (4) <223> LNA-G
<400> 58
uucggagtt 9
<210> 59
<211> 8
741-3589

CA 02677068 2009-09-01
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified-base
<222> (3)
<223> LNA-G
<400> 59
ucggagtt 8
<210> 60
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-C
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 60
cggagtt 7
<210> 61
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<220>
<221> modified base
<222> (16)
<223> LNA-G
<400> 61
741-3590

CA 02677068 2009-09-01
ggaucuuauu ucuucggagt t 21
<210> 62
<211> 25
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 62
ggaucuuauu ucuucggaga caatg 25
<SEQ ID NO. 63;RNA;Artificial Sequence>guauuuugaugaggaguucacggcc
<SEQ ID NO. 64;RNA; Artificial Sequence>ggcccagaugaucaccaucacacca
<SEQ ID NO. 65;RNA;Artificial Sequence>gggaagaaaacuauccugcggguuu
<SEQ ID NO. 66;RNA;Artificial Sequence>guuuuaauuuauuucauccaguuug
<SEQ ID NO. 67;RNA;Artificial Sequence>acguagggaaauguuaaggacuucu
<SEQ ID NO. 68;RNA;Artificial Sequence>ccaggguuuacccagugggacagag
<SEQ ID NO. 69;RNA;Artificial Sequence>agcaagguuuaaauuuguuauugug
<SEQ ID NO. 70;RNA; Artificial Sequence>uguauuauguuguucaaaugcauuu
<SEQ ID NO. 71;RNA; Artificial Sequence>uuuuaaucuuugugacaggaaagcc
<SEQ ID NO. 72;RNA; Artificial Sequence>uuaaucuuugugacaggaaagcccu
<SEQ ID NO. 73;RNA;Artificial Sequence>gcugcuuaugucucccagcauggcc
<SEQ ID NO. 74;RNA;Artificial Sequence>aaguguuucagaagcuucucccuga
<SEQ ID NO. 75;RNA;Artificial Sequence>gaccaucaauaaggaagaagcccuu
<SEQ ID NO. 76;RNA;Artificial Sequence>ccaucaauaaggaagaagcccuuca
<SEQ ID NO. 77;RNA;Artificial Sequence>ucaauaaggaagaagcccuucagcg
<SEQ ID NO. 78;RNA;Artificial Sequence>aauaaggaagaagcccuucagcggc
<SEQ ID NO. 79;RNA;Artificial Sequence>aggaagaagcccuucagcggccagu
<SEQ ID NO. 80;RNA;Artificial Sequence>gcauaacuaaaggugaaaagcuccg
<SEQ ID NO. 81;RNA;Artificial Sequence>cauaacuaaaggugaaaagcuccgg
<SEQ ID NO. 82;RNA;Artificial Sequence>cuacaucacgccagucaacagucug
<SEQ ID NO. 83;RNA;Artificial Sequence>acuggauuuaagcagaguucaaaag
<SEQ ID NO. 84;RNA;Artificial Sequence>cuggauuuaagcagaguucaaaagc
<SEQ ID NO. 85;RNA;Artificial Sequence>gauuuaagcagaguucaaaagcccu
<SEQ ID NO. 86;RNA;Artificial Sequence>auuuaagcagaguucaaaagcccuu
<SEQ ID NO. 87;RNA;Artificial Sequence>uuaagcagaguucaaaagcccuuca
<SEQ ID NO. 88;RNA;Artificial Sequence>uaagcagaguucaaaagcccuucag
<SEQ ID NO. 89;RNA;Artificial Sequence>agcagaguucaaaagcccuucagcg
<SEQ ID NO. 90;RNA;Artificial Sequence>cucagggucugagugaagccgcucg
<SEQ ID NO. 91;RNA;Artificial Sequence>caagcaacuacaucacgccagucaa
<SEQ ID NO. 92;RNA;Artificial Sequence>aucaauggcagcuucuuggugcgug
<SEQ ID NO. 93;RNA;Artificial Sequence>uuccagcccacauuggauucaucag
<SEQ ID NO. 94;RNA;Artificial Sequence>cagcugagaauguggaauaccuaag
<SEQ ID NO. 95;RNA;Artificial Sequence>aacguaucuccuaauuugaggcuca
<SEQ ID NO. 96;RNA;Artificial Sequence>ccuaaaauaauuucucuacaauugg
<SEQ ID NO. 97;RNA;Artificial Sequence>uggaagauucagcuaguuaggagcc
<SEQ ID NO. 98;RNA;Artificial Sequence>uuaaacucuccuagucaauauccac
<SEQ ID NO. 99;RNA;Artificial Sequence>cagccuacaguuauguucagucaca
<SEQ ID NO. 100;RNA;Artificial Sequence> guuauguucagucacacacacauac
<SEQ ID NO. 101;RNA;Artificial Sequence> cacauacaaaauguuccuuuugcuu
<SEQ ID NO. 102;RNA;Artificial Sequence> uccuuuugcuuuuaaaguaauuuuu
<SEQ ID NO. 103;RNA;Artificial Sequence> ugaccugugaagcaacagucaaugg
<SEQ ID NO. 104;RNA;Artificial Sequence> cuaucucacacaucgacaaaccaau
<SEQ ID NO. 105;RNA;Artificial Sequence> uguccucaauuguacugcuaccacu
<SEQ ID NO. 106;RNA;Artificial Sequence> aaaccguagcuggcaagcggucuua
<SEQ ID NO. 107;RNA;Artificial Sequence> uagcuggcaagcggucuuaccggcu
<SEQ ID NO. 108;RNA;Artificial Sequence> uuguaugguuaaaagauggguuacc
<SEQ ID NO. 109;RNA;Artificial Sequence> ugguuaaaagauggguuaccugcga
<SEQ ID NO. 110;RNA;Artificial Sequence> cagggaauuauacaaucuugcugag
<SEQ ID NO. 111;RNA;Artificial Sequence> acaaucuugcugagcauaaaacagu
<SEQ ID NO. 112;RNA;Artificial Sequence> ccaauaaugaagaguccuuuauccu
<SEQ ID NO. 113;RNA;Artificial Sequence> acuuuggauguuccaacgcaaguug
<SEQ ID NO. 114;RNA;Artificial Sequence> aaugcuuccacuaaacugaaaccau
<SEQ ID NO. 115;RNA;Artificial Sequence> gagaaaguuugacuuuguuaaauau
<SEQ ID NO. 116;RNA;Artificial Sequence> aaagaacuacuguauauuaaaaguu
<SEQ ID NO. 117;RNA;Artificial Sequence> uuagaaauacggguuuugacuuaac
741-3591

CA 02677068 2009-09-01
<SEQ ID NO. 118;RNA;Artificial Sequence> aacauggguacagcaaacucagcac
<SEQ ID NO. 119;RNA;Artificial Sequence> aaagacacagaagaugcugaccuca
<SEQ ID NO. 120;RNA;Artificial Sequence> uaguagggagguuuauucagaucgc
<SEQ ID NO. 121;RNA;Artificial Sequence> gccuucugcagcaggguucugggau
<SEQ ID NO. 122;RNA;Artificial Sequence> ggucugguacauauuggaaauuaug
<SEQ ID NO. 123;RNA;Artificial Sequence> cuaguccuuccgauggaagcacuag
<SEQ ID NO. 124;RNA;Artificial Sequence> ccagugaauauuguuuuuaugugga
<SEQ ID NO. 125;RNA;Artificial Sequence> augaauucaaguuggaauugguaga
<SEQ ID NO. 126;RNA;Artificial Sequence> caggacacagauuuagacuuggaga
<SEQ ID NO. 127;RNA;Artificial Sequence> cucaaagcacaguuacaguauucca
<SEQ ID NO. 128;RNA;Artificial Sequence> accacugccaccacugaugaauuaa
<SEQ ID NO. 129;RNA;Artificial Sequence> gaaacuacuagugccacaucaucac
<SEQ ID NO. I30;RNA;Artificial Sequence> aagucggacagccucaccaaacaga
<SEQ ID NO. 131;RNA;Artificial Sequence> gaaagcgaaaaauggaacaugaugg
<SEQ ID NO. 132;RNA;Artificial Sequence> cccucugauuuagcauguagacugc
<SEQ ID NO. 133;RNA;Artificial Sequence> ugagcuauuuaaggaucuauuuaug
<SEQ ID NO. 134;RNA;Artificial Sequence> aaaaggugaaaaagcacuauuauca
<SEQ ID NO. 135;RNA;Artificial Sequence> gaaaaagcacuauuaucaguucugc
<SEQ ID NO. 136;RNA;Artificial Sequence> ggcugaaaagaaagauuaaaccuac
<SEQ ID NO. 137;RNA;Artificial Sequence> uaaacccuuauaauaaaauccuucu
<SEQ ID NO. 138;RNA;Artificial Sequence> cauacuauuagccaaugcuguagac
<SEQ ID NO. 139;RNA;Artificial Sequence> gacagaagcauuuugauaggaauag
<SEQ ID NO. 140;RNA;Artificial Sequence> agagcaaauaagauaauggcccuga
<SEQ ID NO. 141;RNA;Artificial Sequence> ccaacauuuuucucuuccucaagca
<SEQ ID NO. 142;RNA;Artificial Sequence> uuaaguaugagaaaaguucagccca
<SEQ ID NO. 143;RNA;Artificial Sequence> caggaauaaagauggcugcugaacc
<SEQ ID NO. 144;RNA;Artificial Sequence> aauuugaaugaccaaguucucuuca
<SEQ ID NO. 145;RNA;Artificial Sequence> auguauaaagauagccagccuagag
<SEQ ID NO. 146;RNA;Artificial Sequence> ggcuguaacuaucucugugaagugu
<SEQ ID NO. 147;RNA;Artificial Sequence> ucugugaagugugagaaaauuucaa
<SEQ ID NO. 148;RNA;Artificial Sequence> ccuuuaaggaaaugaauccuccuga
<SEQ ID NO. 149;RNA;Artificial Sequence> aaggauacaaaaagugacaucauau
<SEQ ID NO. 150;RNA;Artificial Sequence> agaugcaauuugaaucuucaucaua
<SEQ ID NO. 151;RNA;Artificial Sequence> guucaaaacgaagacuagcuauuaa
<SEQ ID NO. 152;RNA;Artificial Sequence> gugaaaccucaucucuacuaaaaau
<SEQ ID NO. 153;RNA;Artificial Sequence> acgaaagagaagcucuaucucgccu
<SEQ ID NO. 154;RNA;Artificial Sequence> cuccacaagcgccuucgguccaguu
<SEQ ID NO. 155;RNA;Artificial Sequence> gagaagauuccaaagauguagccgc
<SEQ ID NO. 156;RNA;Artificial Sequence> aaucuggauucaaugaggagacuug
<SEQ ID NO. 157;RNA;Artificial Sequence> agaacagauuugagaguagugagga
<SEQ ID NO. 158;RNA;Artificial Sequence> ccagagcugugcagaugaguacaaa
<SEQ ID NO. 159;RNA;Artificial Sequence> ccucagauuguuguuguuaaugggc
<SEQ ID NO. 160;RNA;Artificial Sequence> cuauuuuaauuauuuuuaauuuauu
<SEQ ID NO. 161;RNA;Artificial Sequence> uuuaauuuauuaauauuuaaauaug
<SEQ ID NO. 162;RNA;Artificial Sequence> augcaguuugaauauccuuuguuuc
<SEQ ID NO. 163;RNA;Artificial Sequence> caugcugcuggcgucuaaguguuug
<SEQ ID NO. I64;RNA;Artificial Sequence> agaugugcauuucaccugugacaaa
<SEQ ID NO. 165;RNA;Artificial Sequence> ucaaaaccugugccaggcugaauua
<SEQ ID NO. 166;RNA;Artificial Sequence> gaauguggguagucauucuuacaau
<SEQ ID NO. 167;RNA;Artificial Sequence> auguggguagucauucuuacaauug
<SEQ ID NO. 168;RNA;Artificial Sequence> ugaaaaugagcaucagagaguguac
<SEQ ID NO. 169;RNA;Artificial Sequence> uugcuuuucauguagaacucagcag
<SEQ ID NO. 170;RNA;Artificial Sequence> uguauuucuauauuuauuuucagua
<SEQ ID NO. 171;RNA;Artificial Sequence> uuugauuaauguuucuuaaauggaa
<SEQ ID NO. 172;RNA;Artificial Sequence> caacguguauagugccuaaaauugu
<SEQ ID NO. 173;RNA;Artificial Sequence> cauauccuuggcuacuaacaucugg
<SEQ ID NO. 174;RNA;Artificial Sequence> uacuaacaucuggagacugugagcu
<SEQ ID NO. 175;RNA;Artificial Sequence> cauaaguugugugcuuuuuauuaau
<SEQ ID NO. 176;RNA;Artificial Sequence> gcaucauuuuggcucuucuuacauu
<SEQ ID NO. 177;RNA;Artificial Sequence> gcucuucuuacauuuguaaaaaugu
<SEQ ID NO. 178;RNA;Artificial Sequence> agauuaggucaucuuaauucauauu
<SEQ ID NO. 179;RNA;Artificial Sequence> auggaauugaaagaacuaaucauga
<SEQ ID NO. 180;RNA;Artificial Sequence> cacacucauuccuucugcucuuggg
<SEQ ID NO. 181;RNA;Artificial Sequence> uguagagguaaccaguagcuuugag
<SEQ ID NO. 182;RNA;Artificial Sequence> caaccacaugccacguaauauuuca
<SEQ ID NO. 183;RNA;Artificial Sequence> ucggaaacaaguuauucucuucacu
<SEQ ID NO. 184;RNA;Artificial Sequence> acucccaauaacuaaugcuaagaaa
<SEQ ID NO. 185;RNA;Artificial Sequence> aaugcuaagaaaugcugaaaaucaa
<SEQ ID NO. 186;RNA;Artificial Sequence> gucuuucucuaaauaugauuacuuu
<SEQ ID NO. 187;RNA;Artificial Sequence> ugaauuucaggcauuuuguucuaca
<SEQ ID NO. 188;RNA;Artificial Sequence> cgauucccucucacccgggacucuc
<SEQ ID NO. 189;RNA;Artificial Sequence> aggaaagugaaccuuuaaaguaaag
<SEQ ID NO. 190;RNA;Artificial Sequence> gaggcugcaugcucuggaagccugg
741-3592

CA 02677068 2009-09-01
<SEQ ID NO. 191;RNA;Artificial Sequence> ucucugaacagaaaacaaaagagag
<SEQ ID NO. 192;RNA;Artificial Sequence> aacuuggcuguaaucaguuaugccg
<SEQ ID NO. 193;RNA;Artificial Sequence> agaagccaaaauuaaaagaagucca
<SEQ ID NO. I94;RNA;Artificial Sequence> auuaaaagaaguccaggugagguua
<SEQ ID NO. 195;RNA;Artificial Sequence> gaauccggauuaucgggaagaggac
<SEQ ID NO. 196;RNA;Artificial Sequence> aaugugacaucaaagcaaguauugu
<SEQ ID NO. 197;RNA;Artificial Sequence> caucaaagcaaguauuguagcacuc
<SEQ ID NO. 198;RNA;Artificial Sequence> agagagagaaaacaaaaccacaaau
<SEQ ID NO. 199;RNA;Artificial Sequence> ucgcuguaguauuuaagcccauaca
<SEQ ID NO. 200;RNA;Artificial Sequence> cgcuguaguauuuaagcccauacag
<SEQ ID NO. 201;RNA;Artificial Sequence> auuuaagcccauacagaaaccuucc
<SEQ ID NO. 202;RNA;Artificial Sequence> auuaaaauaaacaugguauaccuac
<SEQ ID NO. 203;RNA;Artificial Sequence> cuguucugaucggccaguuuucgga
<SEQ ID NO. 204;RNA;Artificial Sequence> aaauaauuugaacuuuggaacaggg
<SEQ ID NO. 205;RNA;Artificial Sequence> ugcgaccuuaauuuaacuuuccagu
<SEQ ID NO. 206;RNA;Artificial Sequence> cugagaaagcuaaaguuugguuuug
<SEQ ID NO. 207;RNA;Artificial Sequence> aguaaagaugcuacuucccacugua
<SEQ ID NO. 208;RNA;Artificial Sequence> cugcuuaauugcugauaccauauga
<SEQ ID NO. 209;RNA;Artificial Sequence> uaccauaugaaugaaacaugggcug
<SEQ ID NO. 210;RNA;Artificial Sequence> aacuuucuuauccaacuuuuucaua
<SEQ ID NO.211;RNA;Artificial Sequence> ccuugcaugacaucaugaggccgga
<SEQ ID NO. 212;RNA;Artificial Sequence> ugaauuuguauaugacugcauuugu
<SEQ ID NO. 213;RNA;Artificial Sequence> gaauccuaguagaauguuuacuacc
<SEQ ID NO. 214;RNA;Artificial Sequence> gaaagggaagaauuuuuugaugaaa
<SEQ ID NO. 215;RNA;Artificial Sequence> uaucggcaugccagugugugaauuu
<SEQ ID NO. 216;RNA;Artificial Sequence> caccucauaguagagcaauguaugu
<SEQ ID NO. 217;RNA; Artificial Sequence> ccagaauugccaaagcacauauaua
<SEQ ID NO. 2 1 8;RNA;Artificial Sequence> uggugaucuggguaauaguuucucc
<SEQ ID NO. 219;RNA;Artificial Sequence> gaucuggguaauaguuucuccaaau
<SEQ ID NO. 220;RNA;Artificial Sequence> ggaugugaugaauacuuccuagaaa
<SEQ ID NO. 221;RNA;Artificial Sequence> cauuuccacagcuacaccauauaug
<SEQ ID NO. 222;RNA;Artificial Sequence> acagcuacaccauauaugaauggag
<SEQ ID NO. 223;RNA;Artificial Sequence> ugcaguucuuacacgagaagaagau
<SEQ ID NO. 224;RNA;Artificial Sequence> acgagaagaagaucauuuacaggga
<SEQ ID NO. 225;RNA;Artificial Sequence> cgagaagaagaucauuuacagggac
<SEQ ID NO. 226;RNA;Artificial Sequence> aagaagaucauuuacagggaccuga
<SEQ ID NO. 227;RNA;Artificial Sequence> agaggaagagguguuugacugcauc
<SEQ ID NO. 228;RNA;Artificial Sequence> gaggaagagguguuugacugcaucg
<SEQ ID NO. 229;RNA;Artificial Sequence> cuacuuugagggcgaguucacaggg
<SEQ ID NO. 230;RNA;Artificial Sequence> agggcaucuccuggcaccucugucc
<SEQ ID NO. 231;RNA;Artificial Sequence> ggagugauaugguuugucuuuuuaa
<SEQ ID NO. 232;RNA;Artificial Sequence> gagugauaugguuugucuuuuuaag
<SEQ ID NO. 233;RNA;Artificial Sequence> ugcaguaaagauccuaaagguuguc
<SEQ ID NO. 234;RNA;Artificial Sequence> aguaaagauccuaaagguugucgac
<SEQ ID NO. 235;RNA;Artificial Sequence> ugacaaaggacaaccuggcaauugu
<SEQ ID NO. 236;RNA;Artificial Sequence> gcaauugugacccaguggugcgagg
<SEQ ID NO. 237;RNA;Artificial Sequence> aacaucauccauagagacaugaaau
<SEQ ID NO. 238;RNA;Artificial Sequence> ugaaauccaacaauauauuucucca
<SEQ ID NO. 239;RNA;Artificial Sequence> aacaauauauuucuccaugaaggcu
<SEQ ID NO. 240;RNA;Artificial Sequence> aacaguaaagucacgcuggaguggu
<SEQ ID NO. 241;RNA;Artificial Sequence> ugugaagaaaguaaaggaagagagg
<SEQ ID NO. 242;RNA;Artificial Sequence> cuuccgagccauccuugcaucgggc
<SEQ ID NO. 243;RNA;Artificial Sequence> aauggagguugaauauccuacugug
<SEQ ID NO. 244;RNA;Artificial Sequence> ggagguugaauauccuacuguguaa
<SEQ ID NO. 245;RNA;Artificial Sequence> auuuugaguuuucccuuguagugua
<SEQ ID NO. 246;RNA;Artificial Sequence> uauccuguuuguucuuuguugauug
<SEQ ID NO. 247;RNA;Artificial Sequence> ccuguuuguucuuuguugauugaaa
<SEQ ID NO. 248;RNA;Artificial Sequence> cucuacagccuucuuuuucuuccau
<SEQ ID NO. 249;RNA;Artificial Sequence> ucuuccauagcuaaucuuccuucua
<SEQ ID NO. 250;RNA;Artificial Sequence> auaaucuuccuguugaaugcuucau
<SEQ ID NO. 251 ;RNA;Artificial Sequence> uaaucuuccuguugaaugcuucaug
<SEQ ID NO. 252;RNA;Artificial Sequence> cuucaugacuugaauucuacuuuga
<SEQ ID NO. 253;RNA;Artificial Sequence> aagagggagagaagcaacuacagac
<SEQ ID NO. 254;RNA;Artificial Sequence> cgucuccuaccagaccaaggucaac
<SEQ ID NO. 255;RNA;Artificial Sequence> gaucaaucggcccgacuaucucgac
<SEQ ID NO. 256;RNA;Artificial Sequence> ggacgaacauccaaccuucccaaac
<SEQ ID NO. 257;RNA;Artificial Sequence> agggucggaacccaagcuuagaacu
<SEQ ID NO. 258;RNA;Artificial Sequence> ucggaacccaagcuuagaacuuuaa
<SEQ ID NO. 259;RNA;Artificial Sequence> acccaagcuuagaacuuuaagcaac
<SEQ ID NO. 260;RNA;Artificial Sequence> gaacuuuaagcaacaagaccaccac
<SEQ ID NO. 261;RNA;Artificial Sequence> acuauucaguggcgagaaauaaagu
<SEQ ID NO. 262;RNA;Artificial Sequence> cuauucaguggcgagaaauaaaguu
<SEQ ID NO. 263;RNA;Artificial Sequence> aaacacagauaacaggaaaugaucc
741-3593

CA 02677068 2009-09-01
<SEQ ID NO. 264;RNA;Artificial Sequence> cuuaagaaaagagaagaaaugaaac
<SEQ ID NO. 265;RNA;Artificial Sequence> cugaaggaguguguuuccauccucc
<SEQ ID NO. 266;RNA;Artificial Sequence> ucaccgcgggacugaaaaucuuuga
<SEQ ID NO. 267;RNA;Artificial Sequence> agcagaaauaagcgugccguucagg
<SEQ ID NO. 268;RNA;Artificial Sequence> aagcgugccguucaggguccagaag
<SEQ ID NO.269;RNA;Artificial Sequence> agaaacagucacucaagacugcuug
<SEQ ID NO. 270;RNA;Artificial Sequence> agaggaagaagguccaugucuuugg
<SEQ ID NO. 271;RNA;Artificial Sequence> uguauucaaaauaugccugaaacac
<SEQ ID NO. 272;RNA;Artificial Sequence> auuuuccucccuuucucuguaccuc
<SEQ ID NO. 273;RNA;Artificial Sequence> caaagaaagauagagcaagacaaga
<SEQ ID NO. 274;RNA;Artificial Sequence> aagaaagauagagcaagacaagaaa
<SEQ ID NO. 275;RNA;Artificial Sequence> gaaagcauuuguuuguacaagaucc
<SEQ ID NO. 276;RNA;Artificial Sequence> ugaguuaaacgaacguacuugcaga
<SEQ ID NO. 277;RNA;Artificial Sequence> acugauacagaacgaucgauacaga
<SEQ ID NO. 278;RNA;Artificial Sequence> auauuauauauauauaaaaauaaau
<SEQ ID NO. 279;RNA;Artificial Sequence> auuauauauauauaaaaauaaauau
<SEQ ID NO. 280;RNA;Artificial Sequence> ucacuggauguauuugacugcugug
<SEQ ID NO. 281;RNA;Artificial Sequence> cagggaagaggaggagaugagagac
<SEQ ID NO. 282;RNA;Artificial Sequence> augaucuuuuuuuugucccacuugg
<SEQ ID NO. 283;RNA;Artificial Sequence> ggccgugaacuccucaucaaaauaccu
<SEQ ID NO. 284;RNA;Artificial Sequence> uggugugauggugaucaucugggccgu
<SEQ ID NO. 285;RNA;Artificial Sequence> aaacccgcaggauaguuuucuucccua
<SEQ ID NO. 286;RNA;Artificial Sequence> caaacuggaugaaauaaauuaaaaccc
<SEQ ID NO. 287;RNA;Artificial Sequence> agaaguccuuaacauuucccuacguga
<SEQ ID NO. 288;RNA;Artificial Sequence> cucugucccacuggguaaacccuggcc
<SEQ ID NO. 289;RNA;Artificial Sequence> cacaauaacaaauuuaaaccuugcucc
<SEQ ID NO. 290;RNA;Artificial Sequence> aaaugcauuugaacaacauaauacaca
<SEQ ID NO. 291;RNA;Artificial Sequence> ggcuuuccugucacaaagauuaaaaac
<SEQ ID NO. 292;RNA;Artificial Sequence> agggcuuuccugucacaaagauuaaaa
<SEQ ID NO. 293;RNA;Artificial Sequence> ggccaugcugggagacauaagcagcag
<SEQ ID NO. 294;RNA;Artificial Sequence> ucagggagaagcuucugaaacacuucu
<SEQ ID NO. 295;RNA;Artificial Sequence> aagggcuucuuccuuauugauggucag
<SEQ ID NO. 296;RNA;Artificial Sequence> ugaagggcuucuuccuuauugaugguc
<SEQ ID NO. 297;RNA;Artificial Sequence> cgcugaagggcuucuuccuuauugaug
<SEQ ID NO. 298;RNA;Artificial Sequence> gccgcugaagggcuucuuccuuauuga
<SEQ ID NO. 299;RNA;Artificial Sequence> acuggccgcugaagggcuucuuccuua
<SEQ ID NO. 300;RNA;Artificial Sequence> cggagcuuuucaccuuuaguuaugcuu
<SEQ ID NO. 301;RNA;Artificial Sequence> ccggagcuuuucaccuuuaguuaugcu
<SEQ ID NO. 302;RNA;Artificial Sequence> cagacuguugacuggcgugauguaguu
<SEQ ID NO. 303;RNA;Artificial Sequence> cuuuugaacucugcuuaaauccagugg
<SEQ ID NO. 304;RNA;Artificial Sequence> gcuuuugaacucugcuuaaauccagug
<SEQ ID NO. 305;RNA;Artificial Sequence> agggcuuuugaacucugcuuaaaucca
<SEQ ID NO. 306;RNA;Artificial Sequence> aagggcuuuugaacucugcuuaaaucc
<SEQ ID NO. 307;RNA;Artificial Sequence> ugaagggcuuuugaacucugcuuaaau
<SEQ ID NO. 308;RNA;Artificial Sequence> cugaagggcuuuugaacucugcuuaaa
<SEQ ID NO. 309;RNA;Artificial Sequence> cgcugaagggcuuuugaacucugcuua
<SEQ ID NO.310;RNA;Artificial Sequence> cgagcggcuucacucagacccugaggc
<SEQ ID NO.311;RNA;Artificial Sequence> uugacuggcgugauguaguugcuuggg
<SEQ ID NO. 312;RNA;Artificial Sequence> cacgcaccaagaagcugccauugaucc
<SEQ ID NO. 313;RNA;Artificial Sequence> cugaugaauccaaugugggcuggaauc
<SEQ ID NO. 314;RNA;Artificial Sequence> cuuagguauuccacauucucagcugug
<SEQ ID NO. 315;RNA;Artificial Sequence> ugagccucaaauuaggagauacguuuu
<SEQ ID NO. 316;RNA;Artificial Sequence> ccaauuguagagaaauuauuuuaggaa
<SEQ ID NO. 317;RNA;Artificial Sequence> ggcuccuaacuagcugaaucuuccaau
<SEQ ID NO. 318;RNA;Artificial Sequence> guggauauugacuaggagaguuuaaaa
<SEQ ID NO. 319;RNA;Artificial Sequence> ugugacugaacauaacuguaggcugaa
<SEQ ID NO. 320;RNA;Artificial Sequence> guaugugugugugacugaacauaacug
<SEQ ID NO. 321;RNA;Artificial Sequence> aagcaaaaggaacauuuuguaugugug
<SEQ ID NO. 322;RNA;Artificial Sequence> aaaaauuacuuuaaaagcaaaaggaac
<SEQ ID NO. 323;RNA;Artificial Sequence> ccauugacuguugcuucacaggucaga
<SEQ ID NO. 324;RNA;Artificial Sequence> auugguuugucgaugugugagauaguu
<SEQ ID NO. 325;RNA;Artificial Sequence> agugguagcaguacaauugaggacaag
<SEQ ID NO. 326;RNA;Artificial Sequence> uaagaccgcuugccagcuacgguuuca
<SEQ ID NO. 327;RNA;Artificial Sequence> agccgguaagaccgcuugccagcuacg
<SEQ ID NO.328;RNA;Artificial Sequence> gguaacccaucuuuuaaccauacaacu
<SEQ ID NO. 329;RNA;Artificial Sequence> ucgcagguaacccaucuuuuaaccaua
<SEQ ID NO. 330;RNA;Artificial Sequence> cucagcaagauuguauaauucccugca
<SEQ ID NO. 331;RNA;Artificial Sequence> acuguuuuaugcucagcaagauuguau
<SEQ ID NO. 332;RNA;Artificial Sequence> aggauaaaggacucuucauuauuggaa
<SEQ ID NO. 333;RNA;Artificial Sequence> caacuugcguuggaacauccaaagugu
<SEQ ID NO. 334;RNA;Artificial Sequence> augguuucaguuuaguggaagcauuua
<SEQ ID NO. 335;RNA;Artificial Sequence> auauuuaacaaagucaaacuuucucac
<SEQ ID NO. 336;RNA;Artificial Sequence> aacuuuuaauauacaguaguucuuuuc
741-3594

CA 02677068 2009-09-01
<SEQ ID NO. 337;RNA;Artificial Sequence> guuaagucaaaacccguauuucuaaag
<SEQ ID NO. 338;RNA;Artificial Sequence> gugcugaguuugcuguacccauguuga
<SEQ ID NO. 339;RNA;Artificial Sequence> ugaggucagcaucuucugugucuuuac
<SEQ ID NO. 340;RNA;Artificial Sequence> gcgaucugaauaaaccucccuacuagc
<SEQ ID NO. 341;RNA;Artificial Sequence> aucccagaacccugcugcagaaggcca
<SEQ ID NO. 342;RNA;Artificial Sequence> cauaauuuccaauauguaccagaccuu
<SEQ ID NO. 343;RNA;Artificial Sequence> cuagugcuuccaucggaaggacuaggu
<SEQ ID NO. 344;RNA;Artificial Sequence> uccacauaaaaacaauauucacuggga
<SEQ ID NO. 345;RNA;Artificial Sequence> ucuaccaauuccaacuugaauucauug
<SEQ ID NO. 346;RNA;Artificial Sequence> ucuccaagucuaaaucuguguccugag
<SEQ ID NO. 347;RNA;Artificial Sequence> uggaauacuguaacugugcuuugagga
<SEQ ID NO.348;RNA;Artificial Sequence> uuaauucaucagugguggcagugguag
<SEQ ID NO. 349;RNA;Artificial Sequence> gugaugauguggcacuaguaguuucuu
<SEQ ID NO. 350;RNA;Artificial Sequence> ucuguuuggugaggcuguccgacuuug
<SEQ ID NO. 351;RNA;Artificial Sequence> ccaucauguuccauuuuucgcuuucuc
<SEQ ID NO. 352;RNA;Artificial Sequence> gcagucuacaugcuaaaucagagggua
<SEQ ID NO. 353;RNA;Artificial Sequence> cauaaauagauccuuaaauagcucaaa
<SEQ ID NO. 354;RNA;Artificial Sequence> ugauaauagugcuuuuucaccuuuuuc
<SEQ ID NO. 355;RNA;Artificial Sequence> gcagaacugauaauagugcuuuuucac
<SEQ ID NO. 356;RNA;Artificial Sequence> guagguuuaaucuuucuuuucagccau
<SEQ ID NO. 357;RNA;Artificial Sequence> agaaggauuuuauuauaaggguuuaau
<SEQ ID NO. 358;RNA;Artificial Sequence> gucuacagcauuggcuaauaguaugaa
<SEQ ID NO. 359;RNA;Artificial Sequence> cuauuccuaucaaaaugcuucugucua
<SEQ ID NO. 360;RNA;Artificial Sequence> ucagggccauuaucuuauuugcucuau
<SEQ ID NO. 361;RNA;Artificial Sequence> ugcuugaggaagagaaaaauguugguc
<SEQ ID NO. 362;RNA;Artificial Sequence> ugggcugaacuuuucucauacuuaaag
<SEQ ID NO. 363;RNA;Artificial Sequence> gguucagcagccaucuuuauuccugcg
<SEQ ID NO. 364;RNA;Artificial Sequence> ugaagagaacuuggucauucaaauuuc
<SEQ ID NO. 365;RNA;Artificial Sequence> cucuaggcuggcuaucuuuauacauac
<SEQ ID NO. 366;RNA;Artificial Sequence> acacuucacagagauaguuacagccau
<SEQ ID NO. 367;RNA;Artificial Sequence> uugaaauuuucucacacuucacagaga
<SEQ ID NO.368;RNA;Artificial Sequence> ucaggaggauucauuuccuuaaaggaa
<SEQ ID NO. 369;RNA;Artificial Sequence> auaugaugucacuuuuuguauccuuga
<SEQ ID NO. 370;RNA;Artificial Sequence> uaugaugaagauucaaauugcaucuua
<SEQ ID NO. 371;RNA;Artificial Sequence> uuaauagcuagucuucguuuugaacag
<SEQ ID NO. 372;RNA;Artificial Sequence> auuuuuaguagagaugagguuucacca
<SEQ ID NO. 373;RNA;Artificial Sequence> aggcgagauagagcuucucuuucguuc
<SEQ ID NO. 374;RNA;Artificial Sequence> aacuggaccgaaggcgcuuguggagaa
<SEQ ID NO. 375;RNA;Artificial Sequence> gcggcuacaucuuuggaaucuucuccu
<SEQ ID NO. 376;RNA;Artificial Sequence> caagucuccucauugaauccagauugg
<SEQ ID NO. 377;RNA;Artificial Sequence> uccucacuacucucaaaucuguucugg
<SEQ ID NO. 378;RNA;Artificial Sequence> uuuguacucaucugcacagcucuggcu
<SEQ ID NO. 379;RNA;Artificial Sequence> gcccauuaacaacaacaaucugaggug
<SEQ ID NO. 380;RNA;Artificial Sequence> aauaaauuaaaaauaauuaaaauagug
<SEQ ID NO. 381;RNA;Artificial Sequence> cauauuuaaauauuaauaaauuaaaaa
<SEQ ID NO. 382;RNA;Artificial Sequence> gaaacaaaggauauucaaacugcauag
<SEQ ID NO. 383;RNA;Artificial Sequence> caaacacuuagacgccagcagcauggg
<SEQ ID NO. 384;RNA;Artificial Sequence> uuugucacaggugaaaugcacaucuga
<SEQ ID NO.385;RNA;Artificial Sequence> uaauucagccuggcacagguuuugauc
<SEQ ID NO. 386;RNA;Artificial Sequence> auuguaagaaugacuacccacauucac
<SEQ ID NO. 387;RNA;Artificial Sequence> caauuguaagaaugacuacccacauuc
<SEQ ID NO. 388;RNA;Artificial Sequence> guacacucucugaugcucauuuucaua
<SEQ ID NO. 389;RNA;Artificial Sequence> cugcugaguucuacaugaaaagcaaau
<SEQ ID NO. 390;RNA;Artificial Sequence> uacugaaaauaaauauagaaauacaac
<SEQ ID NO. 391;RNA;Artificial Sequence> uuccauuuaagaaacauuaaucaaaac
<SEQ ID NO. 392;RNA;Artificial Sequence> acaauuuuaggcacuauacacguuguu
<SEQ ID NO. 393;RNA;Artificial Sequence> ccagauguuaguagccaaggauauggu
<SEQ ID NO. 394;RNA;Artificial Sequence> agcucacagucuccagauguuaguagc
<SEQ ID NO. 395;RNA;Artificial Sequence> auuaauaaaaagcacacaacuuauggc
<SEQ ID NO. 396;RNA;Artificial Sequence> aauguaagaagagccaaaaugaugcau
<SEQ ID NO. 397;RNA;Artificial Sequence> acauuuuuacaaauguaagaagagcca
<SEQ ID NO. 398;RNA;Artificial Sequence> aauaugaauuaagaugaccuaaucugu
<SEQ ID NO. 399;RNA;Artificial Sequence> ucaugauuaguucuuucaauuccaucc
<SEQ ID NO. 400;RNA;Artificial Sequence> cccaagagcagaaggaaugagugugca
<SEQ ID NO. 401;RNA;Artificial Sequence> cucaaagcuacugguuaccucuacacc
<SEQ ID NO. 402;RNA;Artificial Sequence> ugaaauauuacguggcaugugguuggg
<SEQ ID NO. 403;RNA;Artificial Sequence> agugaagagaauaacuuguuuccgaag
<SEQ ID NO. 404;RNA;Artificial Sequence> uuucuuagcauuaguuauugggaguga
<SEQ ID NO. 405;RNA;Artificial Sequence> uugauuuucagcauuucuuagcauuag
<SEQ ID NO.406;RNA;Artificial Sequence> aaaguaaucauauuuagagaaagacag
<SEQ ID NO. 407;RNA;Artificial Sequence> uguagaacaaaaugccugaaauucagc
<SEQ ID NO. 408;RNA;Artificial Sequence> gagagucccgggugagagggaaucgcc
<SEQ ID NO. 409;RNA;Artificial Sequence> cuuuacuuuaaagguucacuuuccuug
741-3595

CA 02677068 2009-09-01
<SEQ ID NO. 410;RNA;Artificial Sequence> ccaggcuuccagagcaugcagccuccu
<SEQ ID NO. 41 1;RNA;Artificial Sequence> cucucuuuuguuuucuguucagagaaa
<SEQ ID NO. 412;RNA;Artificial Sequence> cggcauaacugauuacagccaaguuca
<SEQ ID NO. 413;RNA;Artificial Sequence> uggacuucuuuuaauuuuggcuucuuc
<SEQ ID NO. 414;RNA;Artificial Sequence> uaaccucaccuggacuucuuuuaauuu
<SEQ ID NO. 415;RNA;Artificial Sequence> guccucuucccgauaauccggauucag
<SEQ ID NO. 416;RNA;Artificial Sequence> acaauacuugcuuugaugucacauuaa
<SEQ ID NO. 417;RNA;Artificial Sequence> gagugcuacaauacuugcuuugauguc
<SEQ ID NO. 418;RNA;Artificial Sequence> auuugugguuuuguuuucucucucucu
<SEQ ID NO. 419;RNA;Artificial Sequence> uguaugggcuuaaauacuacagcgagg
<SEQ ID NO. 420;RNA;Artificial Sequence> cuguaugggcuuaaauacuacagcgag
<SEQ ID NO. 421;RNA;Artificial Sequence> ggaagguuucuguaugggcuuaaauac
<SEQ ID NO. 422;RNA;Artificial Sequence> guagguauaccauguuuauuuuaauac
<SEQ ID NO. 423;RNA;Artificial Sequence> uccgaaaacuggccgaucagaacagcc
<SEQ ID NO. 424;RNA;Artificial Sequence> cccuguuccaaaguucaaauuauuugu
<SEQ ID NO. 425;RNA;Artificial Sequence> acuggaaaguuaaauuaaggucgcaau
<SEQ ID NO. 426;RNA;Artificial Sequence> caaaaccaaacuuuagcuuucucagcc
<SEQ ID NO. 427;RNA;Artificial Sequence> uacagugggaaguagcaucuuuacuuu
<SEQ ID NO.428;RNA;Artificial Sequence> ucauaugguaucagcaauuaagcagua
<SEQ ID NO. 429;RNA;Artificial Sequence> cagcccauguuucauucauaugguauc
<SEQ ID NO.430;RNA;Artificial Sequence> uaugaaaaaguuggauaagaaaguugg
<SEQ ID NO. 43 1;RNA;Artificial Sequence> uccggccucaugaugucaugcaaggcu
<SEQ ID NO. 432;RNA;Artificial Sequence> acaaaugcagucauauacaaauucagg
<SEQ ID NO. 433;RNA;Artificial Sequence> gguaguaaacauucuacuaggauucuu
<SEQ ID NO. 434;RNA;Artificial Sequence> uuucaucaaaaaauucuucccuuucug
<SEQ ID NO. 435;RNA;Artificial Sequence> aaauucacacacuggcaugccgauagc
<SEQ ID NO. 436;RNA;Artificial Sequence> acauacauugcucuacuaugaggugaa
<SEQ ID NO. 437;RNA;Artificial Sequence> uauauaugugcuuuggcaauucuggug
<SEQ ID NO. 438;RNA;Artificial Sequence> ggagaaacuauuacccagaucaccacu
<SEQ ID NO. 439;RNA;Artificial Sequence> auuuggagaaacuauuacccagaucac
<SEQ ID NO. 440;RNA;Artificial Sequence> uuucuaggaaguauucaucacauccac
<SEQ ID NO. 441;RNA;Artificial Sequence> cauauaugguguagcuguggaaaugcg
<SEQ ID NO. 442;RNA;Artificial Sequence> cuccauucauauaugguguagcugugg
<SEQ ID NO. 443;RNA;Artificial Sequence> aucuucuucucguguaagaacugcagc
<SEQ ID NO.444;RNA;Artificial Sequence> ucccuguaaaugaucuucuucucgugu
<SEQ ID NO. 445;RNA;Artificial Sequence> gucecuguaaaugaucuucuucucgug
<SEQ ID NO. 446;RNA;Artificial Sequence> ucaggucccuguaaaugaucuucuucu
<SEQ ID NO. 447;RNA;Artificial Sequence> gaugcagucaaacaccucuuccucugu
<SEQ ID NO.448;RNA;Artificial Sequence> cgaugcagucaaacaccucuuccucug
<SEQ ID NO. 449;RNA;Artificial Sequence> cccugugaacucgcccucaaaguagcg
<SEQ ID NO. 450;RNA;Artificial Sequence> ggacagaggugccaggagaugcccuca
<SEQ ID NO. 451 ;RNA;Artificial Sequence> uuaaaaagacaaaccauaucacuccuu
<SEQ ID NO. 452;RNA;Artificial Sequence> cuuaaaaagacaaaccauaucacuccu
<SEQ ID NO. 453;RNA;Artificial Sequence> gacaaccuuuaggaucuuuacugcaac
<SEQ ID NO. 454;RNA;Artificial Sequence> gucgacaaccuuuaggaucuuuacugc
<SEQ ID NO. 455;RNA;Artificial Sequence> acaauugccagguuguccuuugucaug
<SEQ ID NO. 456;RNA;Artificial Sequence> ccucgcaccacugggucacaauugcca
<SEQ ID NO. 457;RNA;Artificial Sequence> auuucaugucucuauggaugauguucu
<SEQ ID NO. 458;RNA;Artificial Sequence> uggagaaauauauuguuggauuucaug
<SEQ ID NO. 459;RNA;Artificial Sequence> agccuucauggagaaauauauuguugg
<SEQ ID NO. 460;RNA;Artificial Sequence> accacuccagcgugacuuuacuguugc
<SEQ ID NO. 461;RNA;Artificial Sequence> ccucucuuccuuuacuuucuucacaca
<SEQ ID NO. 462;RNA;Artificial Sequence> gcccgaugcaaggauggcucggaagcg
<SEQ ID NO. 463;RNA;Artificial Sequence> cacaguaggauauucaaccuccauuuc
<SEQ ID NO. 464;RNA;Artificial Sequence> uuacacaguaggauauucaaccuccau
<SEQ ID NO. 465;RNA;Artificial Sequence> uacacuacaagggaaaacucaaaaucu
<SEQ ID NO. 466;RNA;Artificial Sequence> caaucaacaaagaacaaacaggauaaa
<SEQ ID NO. 467;RNA;Artificial Sequence> uuucaaucaacaaagaacaaacaggau
<SEQ ID NO. 468;RNA;Artificial Sequence> auggaagaaaaagaaggcuguagagaa
<SEQ ID NO. 469;RNA;Artificial Sequence> uagaaggaagauuagcuauggaagaaa
<SEQ ID NO. 470;RNA;Artificial Sequence> augaagcauucaacaggaagauuauuu
<SEQ ID NO. 471;RNA;Artificial Sequence> caugaagcauucaacaggaagauuauu
<SEQ ID NO. 472;RNA;Artificial Sequence> ucaaaguagaauucaagucaugaagca
<SEQ ID NO. 473;RNA;Artificial Sequence> gucuguaguugcuucucucccucuuag
<SEQ ID NO. 474;RNA;Artificial Sequence> guugaccuuggucugguaggagacggc
<SEQ ID NO. 475;RNA;Artificial Sequence> gucgagauagucgggccgauugaucuc
<SEQ ID NO. 476;RNA;Artificial Sequence> guuugggaagguuggauguucguccuc
<SEQ ID NO. 477;RNA;Artificial Sequence> aguucuaagcuuggguuccgacccuaa
<SEQ ID NO. 478;RNA;Artificial Sequence> uuaaaguucuaagcuuggguuccgacc
<SEQ ID NO. 479;RNA;Artificial Sequence> guugcuuaaaguucuaagcuuggguuc
<SEQ ID NO.480;RNA;Artificial Sequence> gugguggucuuguugcuuaaaguucua
<SEQ ID NO. 481;RNA;Artificial Sequence> acuuuauuucucgccacugaauaguag
<SEQ ID NO. 482;RNA;Artificial Sequence> aacuuuauuucucgccacugaauagua
741-3596

CA 02677068 2009-09-01
<SEQ ID NO. 483;RNA;Artificial Sequence> ggaucauuuccuguuaucuguguuugu
<SEQ ID NO. 484;RNA;Artificial Sequence> guuucauuucuucucuuuucuuaaggc
<SEQ ID NO. 485;RNA;Artificial Sequence> ggaggauggaaacacacuccuucaguu
<SEQ ID NO. 486;RNA;Artificial Sequence> ucaaagauuuucagucccgcggugaca
<SEQ ID NO. 487;RNA;Artificial Sequence> ccugaacggcacgcuuauuucugcugu
<SEQ ID NO. 488;RNA;Artificial Sequence> cuucuggacccugaacggcacgcuuau
<SEQ ID NO. 489;RNA;Artificial Sequence> caagcagucuugagugacuguuucuuc
<SEQ ID NO. 490;RNA;Artificial Sequence> ccaaagacauggaccuucuuccucuga
<SEQ ID NO. 491;RNA;Artificial Sequence> guguuucaggcauauuuugaauacauc
<SEQ ID NO. 492;RNA;Artificial Sequence> gagguacagagaaagggaggaaaauag
<SEQ ID NO. 493;RNA;Artificial Sequence> ucuugucuugcucuaucuuucuuuggu
<SEQ ID NO. 494;RNA;Artificial Sequence> uuucuugucuugcucuaucuuucuuug
<SEQ ID NO. 495;RNA;Artificial Sequence> ggaucuuguacaaacaaaugcuuucuc
<SEQ ID NO. 496;RNA;Artificial Sequence> ucugcaaguacguucguuuaacucaag
<SEQ ID NO. 497;RNA;Artificial Sequence> ucuguaucgaucguucuguaucagucu
<SEQ ID NO. 498;RNA;Artificial Sequence> auuuauuuuuauauauauauaauauau
<SEQ ID NO. 499;RNA;Artificial Sequence> auauuuauuuuuauauauauauaauau
<SEQ ID NO. 500;RNA; Artificial Sequence> cacagcagucaaauacauccagugaag
<SEQ ID NO. 501;RNA;Artificial Sequence> gucucucaucuccuccucuucccuguc
<SEQ ID NO.502;RNA;Artificial Sequence> ccaagugggacaaaaaaaagaucaugc
<SEQ ID NO. 503;RNA;Artificial Sequence> guauuuugaugagg
<SEQ ID NO. 504;RNA;Artificial Sequence> ggcccagaugau
<SEQ ID NO. 505;RNA;Artificial Sequence> gggaagaaaacuau
<SEQ ID NO. 506;RNA;Artificial Sequence> guuuuaauuuauuuc
<SEQ ID NO. 507;RNA;Artificial Sequence> acguagggaaau
<SEQ ID NO. 508;RNA;Artificial Sequence> ccaggguuuacc
<SEQ ID NO. 509;RNA;Artificial Sequence> agcaagguuua
<SEQ ID NO. 510;RNA;Artificial Sequence> uguauuauguug
<SEQ ID NO. 511;RNA;Artificial Sequence> uuuuaaucuuuguga
<SEQ ID NO. 512;RNA;Artificial Sequence> uuaaucuuugugac
<SEQ ID NO. 513;RNA;Artificial Sequence> gcugcuuaugucu
<SEQ ID NO. 514;RNA;Artificial Sequence> aaguguuucagaag
<SEQ ID NO. 515;RNA;Artificial Sequence> gaccaucaauaag
<SEQ ID NO. 516;RNA;Artificial Sequence> ccaucaauaagga
<SEQ ID NO. 517;RNA;Artificial Sequence> ucaauaaggaagaa
<SEQ ID NO.518;RNA;Artificial Sequence> aauaaggaagaagc
<SEQ ID NO. 519;RNA;Artificial Sequence> aggaagaagcccu
<SEQ ID NO.520;RNA;Artificial Sequence> gcauaacuaaagg
<SEQ ID NO. 521;RNA;Artificial Sequence> cauaacuaaaggug
<SEQ ID NO. 522;RNA;Artificial Sequence> cuacaucacgcc
<SEQ ID NO. 523;RNA;Artificial Sequence> acuggauuuaag
<SEQ ID NO. 524;RNA;Artificial Sequence> cuggauuuaagc
<SEQ ID NO. 525;RNA;Artificial Sequence> gauuuaagcagag
<SEQ ID NO. 526;RNA;Artificial Sequence> auuuaagcagagu
<SEQ ID NO. 527;RNA;Artificial Sequence> uuaagcagaguuc
<SEQ ID NO. 528;RNA;Artificial Sequence> uaagcagaguuca
<SEQ ID NO. 529;RNA;Artificial Sequence> agcagaguucaaaa
<SEQ ID NO. 530;RNA;Artificial Sequence> cucagggucuga
<SEQ ID NO. 531;RNA;Artificial Sequence> caagcaacuacau
<SEQ ID NO.532;RNA;Artificial Sequence> aucaauggcagc
<SEQ ID NO. 533;RNA;Artificial Sequence> uuccagcccac
<SEQ ID NO.534;RNA;Artificial Sequence> cagcugagaaug
<SEQ ID NO. 535;RNA;Artificial Sequence> aacguaucuccua
<SEQ ID NO. 536;RNA;Artificial Sequence> ccuaaaauaauuuc
<SEQ ID NO. 537;RNA;Artificial Sequence> uggaagauucagc
<SEQ ID NO. 538;RNA;Artificial Sequence> uuaaacucuccu
<SEQ ID NO. 539;RNA;Artificial Sequence> cagccuacaguu
<SEQ ID NO. 540;RNA;Artificial Sequence> guuauguucaguc
<SEQ ID NO. 541;RNA;Artificial Sequence> cacauacaaaaug
<SEQ ID NO. 542;RNA;Artificial Sequence> uccuuuugc
<SEQ ID NO. 543;RNA;Artificial Sequence> ugaccugugaag
<SEQ ID NO. 544;RNA;Artificial Sequence> cuaucucacaca
<SEQ ID NO. 545;RNA;Artificial Sequence> uguccucaauugu
<SEQ ID NO. 546;RNA;Artificial Sequence> aaaccguagcug
<SEQ ID NO. 547;RNA;Artificial Sequence> uagcuggcaagc
<SEQ ID NO. 548;RNA;Artificial Sequence> uuguaugguuaaaa
<SEQ ID NO. 549;RNA;Artificial Sequence> ugguuaaaagaugg
<SEQ ID NO. 550;RNA;Artificial Sequence> cagggaauuauac
<SEQ ID NO. 551;RNA;Artificial Sequence> acaaucuugcug
<SEQ ID NO. 552;RNA;Artificial Sequence> ccaauaaugaaga
<SEQ ID NO. 553;RNA;Artificial Sequence> acuuuggauguuc
<SEQ ID NO. 554;RNA;Artificial Sequence> aaugcuuccacu
<SEQ ID NO. 555;RNA;Artificial Sequence> gagaaaguuug
741-3597

CA 02677068 2009-09-01
<SEQ ID NO. 556;RNA;Artificial Sequence> aaagaacuacu
<SEQ ID NO. 557;RNA;Artificial Sequence> uuagaaauacgg
<SEQ ID NO. 558;RNA;Artificial Sequence> aacauggguaca
<SEQ ID NO. 559;RNA;Artificial Sequence> aaagacacagaaga
<SEQ ID NO. 560;RNA;Artificial Sequence> uaguagggagg
<SEQ ID NO. 561;RNA;Artificial Sequence> gccuucugcagc
<SEQ ID NO. 562;RNA;Artificial Sequence> ggucugguac
<SEQ ID NO. 563;RNA;Artificial Sequence> cuaguccuuccg
<SEQ ID NO. 564;RNA;Artificial Sequence> ccagugaauauu
<SEQ ID NO. 565;RNA;Artificial Sequence> augaauucaaguu
<SEQ ID NO. 566;RNA;Artificial Sequence> caggacacagau
<SEQ ID NO. 567;RNA;Artificial Sequence> cucaaagcacag
<SEQ ID NO. 568;RNA;Artificial Sequence> accacugcca
<SEQ ID NO. 569;RNA;Artificial Sequence> gaaacuacuagug
<SEQ ID NO. 570;RNA;Artificial Sequence> aagucggacagc
<SEQ ID NO. 571;RNA;Artificial Sequence> gaaagcgaaaaau
<SEQ ID NO. 572;RNA;Artificial Sequence> cccucugauuuag
<SEQ ID NO. 573;RNA;Artificial Sequence> ugagcuauuuaa
<SEQ ID NO. 574;RNA;Artificial Sequence> aaaaggugaaaaa
<SEQ ID NO. 575;RNA;Artificial Sequence> gaaaaagcacuauu
<SEQ ID NO. 576;RNA;Artificial Sequence> ggcugaaaagaa
<SEQ ID NO. 577;RNA;Artificial Sequence> uaaacccuuaua
<SEQ ID NO. 578;RNA;Artificial Sequence> cauacuauuagcc
<SEQ ID NO. 579;RNA;Artificial Sequence> gacagaagcauu
<SEQ ID NO. 580;RNA;Artificial Sequence> agagcaaauaagau
<SEQ ID NO. 581;RNA;Artificial Sequence> ccaacauuuuucuc
<SEQ ID NO. 582;RNA;Artificial Sequence> uuaaguaugagaaaa
<SEQ ID NO. 583;RNA;Artificial Sequence> caggaauaaagaug
<SEQ ID NO. 584;RNA;Artificial Sequence> aauuugaaugacc
<SEQ ID NO. 585;RNA;Artificial Sequence> auguauaaagauag
<SEQ ID NO. 586;RNA;Artificial Sequence> ggcuguaacuau
<SEQ ID NO. 587;RNA;Artificial Sequence> ucugugaagug
<SEQ ID NO. 588;RNA;Artificial Sequence> ccuuuaaggaaaug
<SEQ ID NO. 589;RNA;Artificial Sequence> aaggauacaaaaa
<SEQ ID NO. 590;RNA;Artificial Sequence> agaugcaauuug
<SEQ ID NO. 591;RNA;Artificial Sequence> guucaaaacgaa
<SEQ ID NO. 592;RNA;Artificial Sequence> gugaaaccuca
<SEQ ID NO. 593;RNA;Artificial Sequence> acgaaagagaagc
<SEQ ID NO. 594;RNA;Artificial Sequence> cuccacaagcgc
<SEQ ID NO. 595;RNA;Artificial Sequence> gagaagauuccaaa
<SEQ ID NO. 596;RNA;Artificial Sequence> aaucuggauucaa
<SEQ ID NO. 597;RNA;Artificial Sequence> agaacagauuuga
<SEQ ID NO. 598;RNA;Artificial Sequence> ccagagcugug
<SEQ ID NO. 599;RNA;Artificial Sequence> ccucagauuguu
<SEQ ID NO. 600;RNA;Artificial Sequence> cuauuuuaauua
<SEQ ID NO. 601;RNA;Artificial Sequence> uuuaauuuauuaa
<SEQ ID NO. 602;RNA;Artificial Sequence> augcaguuugaa
<SEQ ID NO. 603;RNA;Artificial Sequence> caugcugcugg
<SEQ ID NO. 604;RNA;Artificial Sequence> agaugugcauuuc
<SEQ ID NO. 605;RNA;Artificial Sequence> ucaaaaccugug
<SEQ ID NO. 606;RNA;Artificial Sequence> gaaugugggua
<SEQ ID NO. 607;RNA;Artificial Sequence> auguggguag
<SEQ ID NO. 608;RNA;Artificial Sequence> ugaaaaugagcau
<SEQ ID NO. 609;RNA;Artificial Sequence> uugcuuuucaugu
<SEQ ID NO. 610;RNA;Artificial Sequence> uguauuucuaua
<SEQ ID NO. 611;RNA;Artificial Sequence> uuugauuaauguu
<SEQ ID NO. 612;RNA;Artificial Sequence> caacguguauag
<SEQ ID NO. 613;RNA;Artificial Sequence> cauauccuuggc
<SEQ ID NO. 614;RNA;Artificial Sequence> uacuaacaucugg
<SEQ ID NO. 615;RNA;Artificial Sequence> cauaaguugug
<SEQ ID NO. 616;RNA;Artificial Sequence> gcaucauuuugg
<SEQ ID NO. 617;RNA;Artificial Sequence> gcucuucuua
<SEQ ID NO. 618;RNA;Artificial Sequence> agauuagguc
<SEQ ID NO. 619;RNA;Artificial Sequence> auggaauugaaa
<SEQ ID NO. 620;RNA;Artificial Sequence> cacacucauuccu
<SEQ ID NO. 621;RNA;Artificial Sequence> uguagagguaac
<SEQ ID NO. 622;RNA;Artificial Sequence> caaccacaugc
<SEQ ID NO. 623;RNA;Artificial Sequence> ucggaaacaagu
<SEQ ID NO. 624;RNA;Artificial Sequence> acucccaauaa
<SEQ ID NO. 625;RNA;Artificial Sequence> aaugcuaagaaau
<SEQ ID NO. 626;RNA;Artificial Sequence> gucuuucucua
<SEQ ID NO. 627;RNA;Artificial Sequence> ugaauuucagg
<SEQ ID NO. 628;RNA;Artificial Sequence> cgauucccucuca
741-3598

CA 02677068 2009-09-01
<SEQ ID NO. 629;RNA;Artificial Sequence> aggaaagugaa
<SEQ ID NO. 630;RNA;Artificial Sequence> gaggcugcaugc
<SEQ ID NO. 631;RNA;Artificial Sequence> ucucugaacag
<SEQ ID NO. 632;RNA;Artificial Sequence> aacuuggcugua
<SEQ ID NO. 633;RNA;Artificial Sequence> agaagccaaaau
<SEQ ID NO. 634;RNA;Artificial Sequence> auuaaaagaagucc
<SEQ ID NO. 635;RNA;Artificial Sequence> gaauccggauuauc
<SEQ ID NO. 636;RNA;Artificial Sequence> aaugugacauca
<SEQ ID NO. 637;RNA;Artificial Sequence> caucaaagcaagu
<SEQ ID NO. 638;RNA; Artificial Sequence> agagagagaaa
<SEQ ID NO. 639;RNA; Artificial Sequence> ucgcuguaguauu
<SEQ ID NO. 640;RNA;Artificial Sequence> cgcuguaguauuua
<SEQ ID NO. 641;RNA;Artificial Sequence> auuuaagcccaua
<SEQ ID NO. 642;RNA;Artificial Sequence> auuaaaauaaacaug
<SEQ ID NO. 643;RNA;Artificial Sequence> cuguucugaucg
<SEQ ID NO. 644;RNA;Artificial Sequence> aaauaauuugaacuuu
<SEQ ID NO. 645;RNA;Artificial Sequence> ugcgaccuuaau
<SEQ ID NO. 646;RNA;Artificial Sequence> cugagaaagcu
<SEQ ID NO. 647;RNA;Artificial Sequence> aguaaagaugcua
<SEQ ID NO. 648;RNA;Artificial Sequence> cugcuuaauugc
<SEQ ID NO. 649;RNA;Artificial Sequence> uaccauaugaauga
<SEQ ID NO. 650;RNA;Artificial Sequence> aacuuucuuauc
<SEQ ID NO. 651;RNA;Artificial Sequence> ccuugcaugacau
<SEQ ID NO. 652;RNA;Artificial Sequence> ugaauuuguauaug
<SEQ ID NO. 653;RNA;Artificial Sequence> gaauccuaguag
<SEQ ID NO. 654;RNA;Artificial Sequence> gaaagggaag
<SEQ ID NO. 655;RNA;Artificial Sequence> uaucggcaugc
<SEQ ID NO. 656;RNA;Artificial Sequence> caccucauagua
<SEQ ID NO. 657;RNA;Artificial Sequence> ccagaauugcc
<SEQ ID NO. 658;RNA;Artificial Sequence> uggugaucugg
<SEQ ID NO. 659;RNA;Artificial Sequence> gaucuggguaau
<SEQ ID NO. 660;RNA;Artificial Sequence> ggaugugaugaa
<SEQ ID NO.661;RNA;Artificial Sequence> cauuuccacagc
<SEQ ID NO. 662;RNA;Artificial Sequence> acagcuacacc
<SEQ ID NO. 663;RNA;Artificial Sequence> ugcaguucuuac
<SEQ ID NO. 664;RNA;Artificial Sequence> acgagaagaaga
<SEQ ID NO. 665;RNA;Artificial Sequence> cgagaagaagau
<SEQ ID NO. 666;RNA;Artificial Sequence> aagaagaucauuuac
<SEQ ID NO. 667;RNA;Artificial Sequence> agaggaagagg
<SEQ ID NO. 668;RNA;Artificial Sequence> gaggaagaggug
<SEQ ID NO.669;RNA;Artificial Sequence> cuacuuugagggc
<SEQ ID NO. 670;RNA;Artificial Sequence> agggcaucuccu
<SEQ ID NO. 671;RNA;Artificial Sequence> ggagugauau
<SEQ ID NO. 672;RNA;Artificial Sequence> gagugauaugg
<SEQ ID NO. 673;RNA;Artificial Sequence> ugcaguaaagau
<SEQ ID NO. 674;RNA;Artificial Sequence> aguaaagauccua
<SEQ ID NO. 675;RNA;Artificial Sequence> ugacaaaggaca
<SEQ ID NO. 676;RNA;Artificial Sequence> gcaauugugaccc
<SEQ ID NO. 677;RNA;Artificial Sequence> aacaucauccau
<SEQ ID NO. 678;RNA;Artificial Sequence> ugaaauccaaca
<SEQ ID NO. 679;RNA;Artificial Sequence> aacaauauauuucuc
<SEQ ID NO. 680;RNA;Artificial Sequence> aacaguaaagucac
<SEQ ID NO. 681;RNA;Artificial Sequence> ugugaagaaaguaa
<SEQ ID NO. 682;RNA;Artificial Sequence> cuuccgagccauc
<SEQ ID NO. 683;RNA;Artificial Sequence> aauggagguuga
<SEQ ID NO. 684;RNA;Artificial Sequence> ggagguugaaua
<SEQ ID NO. 685;RNA;Artificial Sequence> auuuugaguuuuc
<SEQ ID NO. 686;RNA;Artificial Sequence> uauccuguuugu
<SEQ ID NO. 687;RNA;Artificial Sequence> ccuguuuguuc
<SEQ ID NO. 688;RNA;Artificial Sequence> cucuacagcc
<SEQ ID NO. 689;RNA;Artificial Sequence> ucuuccauagcu
<SEQ ID NO. 690;RNA;Artificial Sequence> auaaucuuccug
<SEQ ID NO. 691;RNA;Artificial Sequence> uaaucuuccugu
<SEQ ID NO. 692;RNA;Artificial Sequence> cuucaugacuug
<SEQ ID NO. 693;RNA;Artificial Sequence> aagagggagaga
<SEQ ID NO. 694;RNA;Artificial Sequence> cgucuccuacca
<SEQ ID NO. 695;RNA;Artificial Sequence> gaucaaucggcc
<SEQ ID NO. 696;RNA;Artificial Sequence> ggacgaacaucc
<SEQ ID NO. 697;RNA;Artificial Sequence> agggucggaac
<SEQ ID NO. 698;RNA;Artificial Sequence> ucggaaccca
<SEQ ID NO. 699;RNA;Artificial Sequence> acccaagcuua
<SEQ ID NO. 700;RNA;Artificial Sequence> gaacuuuaagcaac
<SEQ ID NO. 701;RNA;Artificial Sequence> acuauucagug
741-3599

CA 02677068 2009-09-01
<SEQ ID NO. 702;RNA;Artificial Sequence> cuauucagugg
<SEQ ID NO. 703;RNA;Artificial Sequence> aaacacagauaac
<SEQ ID NO. 704;RNA;Artificial Sequence> cuuaagaaaaga
<SEQ ID NO. 705;RNA;Artificial Sequence> cugaaggagugu
<SEQ ID NO. 706; RNA; Artificial Sequence> ucaccgcggg
<SEQ ID NO.707;RNA;Artificial Sequence> agcagaaauaagcg
<SEQ ID NO. 708;RNA;Artificial Sequence> aagcgugccguu
<SEQ ID NO. 709;RNA;Artificial Sequence> agaaacagucac
<SEQ ID NO.710;RNA;Artificial Sequence> agaggaagaagg
<SEQ ID NO. 71 1;RNA;Artificial Sequence> uguauucaaaauau
<SEQ ID NO. 712;RNA;Artificial Sequence> auuuuccucccuu
<SEQ ID NO.713;RNA;Artificial Sequence> caaagaaagauag
<SEQ ID NO. 714;RNA;Artificial Sequence> aagaaagauaga
<SEQ ID NO. 715;RNA;Artificial Sequence> gaaagcauuuguu
<SEQ ID NO. 716;RNA;Artificial Sequence> ugaguuaaacgaa
<SEQ ID NO. 717;RNA;Artificial Sequence> acugauacagaa
<SEQ ID NO. 718;RNA;Artificial Sequence> auauuauauaua
<SEQ ID NO. 719;RNA;Artificial Sequence> auuauauauaua
<SEQ ID NO. 720;RNA;Artificial Sequence> ucacuggaugua
<SEQ ID NO. 721;RNA;Artificial Sequence> cagggaagagga
<SEQ ID NO. 722;RNA;Artificial Sequence> augaucuuuuuuuug
<SEQ ID NO. 723;RNA;Artificial Sequence> aguucacggcc
<SEQ ID NO. 724;RNA;Artificial Sequence> caccaucacacca
<SEQ ID NO. 725;RNA;Artificial Sequence> ccugcggguuu
<SEQ ID NO. 726;RNA;Artificial Sequence> auccaguuug
<SEQ ID NO. 727;RNA;Artificial Sequence> guuaaggacuucu
<SEQ ID NO. 728;RNA;Artificial Sequence> cagugggacagag
<SEQ ID NO. 729;RNA;Artificial Sequence> aauuuguuauugug
<SEQ ID NO. 730;RNA;Artificial Sequence> uucaaaugcauuu
<SEQ ID NO.731;RNA;Artificial Sequence> caggaaagcc
<SEQ ID NO. 732;RNA;Artificial Sequence> aggaaagcccu
<SEQ ID NO.733;RNA;Artificial Sequence> cccagcauggcc
<SEQ ID NO. 734;RNA;Artificial Sequence> cuucucccuga
<SEQ ID NO. 735;RNA;Artificial Sequence> gaagaagcccuu
<SEQ ID NO. 736;RNA;Artificial Sequence> agaagcccuuca
<SEQ ID NO. 737;RNA;Artificial Sequence> gcccuucagcg
<SEQ ID NO. 738;RNA;Artificial Sequence> ccuucagcggc
<SEQ ID NO.739;RNA;Artificial Sequence> ucagcggccagu
<SEQ ID NO. 740;RNA;Artificial Sequence> ugaaaagcuccg
<SEQ ID NO. 741;RNA;Artificial Sequence> aaaagcuccgg
<SEQ ID NO. 742;RNA;Artificial Sequence> agucaacagucug
<SEQ ID NO. 743;RNA;Artificial Sequence> cagaguucaaaag
<SEQ ID NO. 744;RNA;Artificial Sequence> agaguucaaaagc
<SEQ ID NO. 745;RNA;Artificial Sequence> uucaaaagcccu
<SEQ ID NO. 746;RNA;Artificial Sequence> ucaaaagcccuu
<SEQ ID NO. 747;RNA;Artificial Sequence> aaaagcccuuca
<SEQ ID NO.748;RNA;Artificial Sequence> aaagcccuucag
<SEQ ID NO. 749;RNA;Artificial Sequence> gugaagccgcucg
<SEQ ID NO. 750;RNA;Artificial Sequence> cacgccagucaa
<SEQ ID NO. 751;RNA;Artificial Sequence> uucuuggugcgug
<SEQ ID NO. 752;RNA;Artificial Sequence> auuggauucaucag
<SEQ ID NO. 753;RNA;Artificial Sequence> uggaauaccuaag
<SEQ ID NO. 754;RNA;Artificial Sequence> auuugaggcuca
<SEQ ID NO. 755;RNA;Artificial Sequence> ucuacaauugg
<SEQ ID NO.756;RNA;Artificial Sequence> uaguuaggagcc
<SEQ ID NO. 757;RNA;Artificial Sequence> agucaauauccac
<SEQ ID NO. 758;RNA;Artificial Sequence> auguucagucaca
<SEQ ID NO. 759;RNA;Artificial Sequence> acacacacauac
<SEQ ID NO. 760;RNA;Artificial Sequence> uuccuuuugcuu
<SEQ ID NO. 761;RNA;Artificial Sequence> uuuuaaaguaauuuuu
<SEQ ID NO. 762;RNA;Artificial Sequence> caacagucaaugg
<SEQ ID NO.763;RNA;Artificial Sequence> ucgacaaaccaau
<SEQ ID NO. 764;RNA;Artificial Sequence> acugcuaccacu
<SEQ ID NO. 765;RNA;Artificial Sequence> gcaagcggucuua
<SEQ ID NO. 766;RNA;Artificial Sequence> ggucuuaccggcu
<SEQ ID NO. 767;RNA;Artificial Sequence> gauggguuacc
<SEQ ID NO. 768;RNA;Artificial Sequence> guuaccugcga
<SEQ ID NO. 769;RNA;Artificial Sequence> aaucuugcugag
<SEQ ID NO. 770;RNA;Artificial Sequence> agcauaaaacagu
<SEQ ID NO. 771;RNA;Artificial Sequence> guccuuuauccu
<SEQ ID NO. 772;RNA;Artificial Sequence> caacgcaaguug
<SEQ ID NO. 773;RNA;Artificial Sequence> aaacugaaaccau
<SEQ ID NO. 774;RNA;Artificial Sequence> acuuuguuaaauau
741-3600

CA 02677068 2009-09-01
<SEQ ID NO. 775;RNA;Artificial Sequence> guauauuaaaaguu
<SEQ ID NO. 776;RNA;Artificial Sequence> guuuugacuuaac
<SEQ ID NO. 777;RNA;Artificial Sequence> gcaaacucagcac
<SEQ ID NO. 778;RNA;Artificial Sequence> ugcugaccuca
<SEQ ID NO. 779;RNA;Artificial Sequence> uuuauucagaucgc
<SEQ ID NO. 780;RNA;Artificial Sequence> aggguucugggau
<SEQ ID NO. 781;RNA;Artificial Sequence> auauuggaaauuaug
<SEQ ID NO. 782;RNA;Artificial Sequence> auggaagcacuag
<SEQ ID NO. 783;RNA;Artificial Sequence> guuuuuaugugga
<SEQ ID NO. 784;RNA;Artificial Sequence> ggaauugguaga
<SEQ ID NO. 785;RNA;Artificial Sequence> uuagacuuggaga
<SEQ ID NO. 786;RNA;Artificial Sequence> uuacaguauucca
<SEQ ID NO. 787;RNA;Artificial Sequence> ccacugaugaauuaa
<SEQ ID NO. 788;RNA;Artificial Sequence> ccacaucaucac
<SEQ ID NO. 789;RNA;Artificial Sequence> cucaccaaacaga
<SEQ ID NO. 790;RNA;Artificial Sequence> ggaacaugaugg
<SEQ ID NO. 791;RNA;Artificial Sequence> cauguagacugc
<SEQ ID NO. 792;RNA;Artificial Sequence> ggaucuauuuaug
<SEQ ID NO. 793;RNA;Artificial Sequence> gcacuauuauca
<SEQ ID NO. 794;RNA;Artificial Sequence> aucaguucugc
<SEQ ID NO. 795;RNA;Artificial Sequence> agauuaaaccuac
<SEQ ID NO. 796;RNA;Artificial Sequence> auaaaauccuucu
<SEQ ID NO. 797;RNA; Artificial Sequence> aaugcuguagac
<SEQ ID NO. 798;RNA;Artificial Sequence> uugauaggaauag
<SEQ ID NO. 799;RNA;Artificial Sequence> aauggcccuga
<SEQ ID NO. 800;RNA;Artificial Sequence> uuccucaagca
<SEQ ID NO. 801;RNA;Artificial Sequence> guucagccca
<SEQ ID NO. 802;RNA;Artificial Sequence> gcugcugaacc
<SEQ ID NO. 803;RNA;Artificial Sequence> aaguucucuuca
<SEQ ID NO. 804;RNA;Artificial Sequence> ccagccuagag
<SEQ ID NO. 805;RNA;Artificial Sequence> cucugugaagugu
<SEQ ID NO. 806;RNA;Artificial Sequence> ugagaaaauuucaa
<SEQ ID NO. 807;RNA;Artificial Sequence> aauccuccuga
<SEQ ID NO. 808;RNA;Artificial Sequence> gugacaucauau
<SEQ ID NO. 809;RNA;Artificial Sequence> aaucuucaucaua
<SEQ ID NO.810;RNA;Artificial Sequence> gacuagcuauuaa
<SEQ ID NO. 811;RNA;Artificial Sequence> ucucuacuaaaaau
<SEQ ID NO. 812;RNA;Artificial Sequence> ucuaucucgccu
<SEQ ID NO. 813;RNA;Artificial Sequence> cuucgguccaguu
<SEQ ID NO. 814;RNA;Artificial Sequence> gauguagccgc
<SEQ ID NO. 815;RNA;Artificial Sequence> ugaggagacuug
<SEQ ID NO. 816;RNA;Artificial Sequence> gaguagugagga
<SEQ ID NO. 817;RNA;Artificial Sequence> cagaugaguacaaa
<SEQ ID NO. 818;RNA;Artificial Sequence> guuguuaaugggc
<SEQ ID NO. 819;RNA;Artificial Sequence> uuuuuaauuuauu
<SEQ ID NO. 820;RNA;Artificial Sequence> uauuuaaauaug
<SEQ ID NO. 821;RNA;Artificial Sequence> uauccuuuguuuc
<SEQ ID NO. 822;RNA;Artificial Sequence> cgucuaaguguuug
<SEQ ID NO. 823;RNA;Artificial Sequence> accugugacaaa
<SEQ ID NO. 824;RNA;Artificial Sequence> ccaggcugaauua
<SEQ ID NO. 825;RNA;Artificial Sequence> gucauucuuacaau
<SEQ ID NO. 826;RNA;Artificial Sequence> ucauucuuacaauug
<SEQ ID NO. 827;RNA;Artificial Sequence> cagagaguguac
<SEQ ID NO. 828;RNA;Artificial Sequence> agaacucagcag
<SEQ ID NO. 829;RNA;Artificial Sequence> uuuauuuucagua
<SEQ ID NO. 830;RNA;Artificial Sequence> ucuuaaauggaa
<SEQ ID NO. 831;RNA;Artificial Sequence> ugccuaaaauugu
<SEQ ID NO. 832;RNA;Artificial Sequence> agacugugagcu
<SEQ ID NO. 833;RNA;Artificial Sequence> ugcuuuuuauuaau
<SEQ ID NO. 834;RNA;Artificial Sequence> cucuucuuacauu
<SEQ ID NO. 835;RNA;Artificial Sequence> cauuuguaaaaaugu
<SEQ ID NO. 836;RNA;Artificial Sequence> aucuuaauucauauu
<SEQ ID NO. 837;RNA;Artificial Sequence> gaacuaaucauga
<SEQ ID NO. 838;RNA;Artificial Sequence> ucugcucuuggg
<SEQ ID NO. 839;RNA;Artificial Sequence> caguagcuuugag
<SEQ ID NO. 840;RNA;Artificial Sequence> cacguaauauuuca
<SEQ ID NO. 841;RNA;Artificial Sequence> uauucucuucacu
<SEQ ID NO. 842;RNA;Artificial Sequence> cuaaugcuaagaaa
<SEQ ID NO. 843;RNA;Artificial Sequence> gcugaaaaucaa
<SEQ ID NO. 844;RNA;Artificial Sequence> aauaugauuacuuu
<SEQ ID NO. 845;RNA;Artificial Sequence> cauuuuguucuaca
<SEQ ID NO. 846;RNA;Artificial Sequence> cccgggacucuc
<SEQ ID NO. 847;RNA;Artificial Sequence> ccuuuaaaguaaag
741-3601

CA 02677068 2009-09-01
<SEQ ID NO. 848;RNA;Artificial Sequence> ucuggaagccugg
<SEQ ID NO. 849;RNA;Artificial Sequence> aaaacaaaagagag
<SEQ ID NO. 850;RNA;Artificial Sequence> aucaguuaugccg
<SEQ ID NO. 851;RNA;Artificial Sequence> uaaaagaagucca
<SEQ ID NO. 852;RNA;Artificial Sequence> aggugagguua
<SEQ ID NO. 853;RNA;Artificial Sequence> gggaagaggac
<SEQ ID NO. 854;RNA;Artificial Sequence> aagcaaguauugu
<SEQ ID NO. 855;RNA;Artificial Sequence> auuguagcacuc
<SEQ ID NO. 856;RNA;Artificial Sequence> acaaaaccacaaau
<SEQ ID NO. 857;RNA;Artificial Sequence> uaagcccauaca
<SEQ ID NO. 858;RNA;Artificial Sequence> agcccauacag
<SEQ ID NO. 859;RNA;Artificial Sequence> cagaaaccuucc
<SEQ ID NO. 860;RNA;Artificial Sequence> guauaccuac
<SEQ ID NO. 861;RNA;Artificial Sequence> gccaguuuucgga
<SEQ ID NO. 862;RNA;Artificial Sequence> ggaacaggg
<SEQ ID NO. 863;RNA;Artificial Sequence> uuaacuuuccagu
<SEQ ID NO. 864;RNA;Artificial Sequence> aaaguuugguuuug
<SEQ ID NO. 865;RNA;Artificial Sequence> cuucccacugua
<SEQ ID NO. 866;RNA;Artificial Sequence> ugauaccauauga
<SEQ ID NO. 867;RNA;Artificial Sequence> aacaugggcug
<SEQ ID NO. 868;RNA;Artificial Sequence> caacuuuuucaua
<SEQ ID NO. 869;RNA;Artificial Sequence> caugaggccgga
<SEQ ID NO. 870;RNA;Artificial Sequence> acugcauuugu
<SEQ ID NO. 871;RNA;Artificial Sequence> aauguuuacuacc
<SEQ ID NO. 872;RNA;Artificial Sequence> aauuuuuugaugaaa
<SEQ ID NO. 873;RNA;Artificial Sequence> cagugugugaauuu
<SEQ ID NO. 874;RNA;Artificial Sequence> gagcaauguaugu
<SEQ ID NO. 875;RNA;Artificial Sequence> aaagcacauauaua
<SEQ ID NO. 876;RNA;Artificial Sequence> guaauaguuucucc
<SEQ ID NO. 877;RNA;Artificial Sequence> aguuucuccaaau
<SEQ ID NO. 878;RNA;Artificial Sequence> uacuuccuagaaa
<SEQ ID NO. 879;RNA;Artificial Sequence> uacaccauauaug
<SEQ ID NO. 880;RNA;Artificial Sequence> auauaugaauggag
<SEQ ID NO. 881;RNA;Artificial Sequence> acgagaagaagau
<SEQ ID NO. 882;RNA;Artificial Sequence> ucauuuacaggga
<SEQ ID NO. 883;RNA;Artificial Sequence> cauuuacagggac
<SEQ ID NO. 884;RNA;Artificial Sequence> agggaccuga
<SEQ ID NO. 885;RNA;Artificial Sequence> uguuugacugcauc
<SEQ ID NO. 886;RNA;Artificial Sequence> uuugacugcaucg
<SEQ ID NO. 887;RNA;Artificial Sequence> gaguucacaggg
<SEQ ID NO. 888;RNA;Artificial Sequence> ggcaccucugucc
<SEQ ID NO. 889;RNA;Artificial Sequence> gguuugucuuuuuaa
<SEQ ID NO. 890;RNA;Artificial Sequence> uuugucuuuuuaag
<SEQ ID NO. 891;RNA;Artificial Sequence> ccuaaagguuguc
<SEQ ID NO. 892;RNA;Artificial Sequence> aagguugucgac
<SEQ ID NO. 893;RNA;Artificial Sequence> accuggcaauugu
<SEQ ID NO. 894;RNA;Artificial Sequence> aguggugcgagg
<SEQ ID NO. 895;RNA;Artificial Sequence> agagacaugaaau
<SEQ ID NO. 896;RNA;Artificial Sequence> auauauuucucca
<SEQ ID NO. 897;RNA;Artificial Sequence> caugaaggcu
<SEQ ID NO. 898;RNA;Artificial Sequence> gcuggaguggu
<SEQ ID NO. 899;RNA;Artificial Sequence> aggaagagagg
<SEQ ID NO. 900;RNA;Artificial Sequence> cuugcaucgggc
<SEQ ID NO. 901;RNA;Artificial Sequence> auauccuacugug
<SEQ ID NO. 902;RNA;Artificial Sequence> uccuacuguguaa
<SEQ ID NO. 903;RNA;Artificial Sequence> ccuuguagugua
<SEQ ID NO. 904;RNA;Artificial Sequence> ucuuuguugauug
<SEQ ID NO. 905;RNA;Artificial Sequence> uuuguugauugaaa
<SEQ ID NO. 906;RNA;Artificial Sequence> uucuuuuucuuccau
<SEQ ID NO. 907;RNA;Artificial Sequence> aaucuuccuucua
<SEQ ID NO. 908;RNA;Artificial Sequence> uugaaugcuucau
<SEQ ID NO. 909;RNA;Artificial Sequence> ugaaugcuucaug
<SEQ ID NO. 910;RNA;Artificial Sequence> aauucuacuuuga
<SEQ ID NO. 911 ;RNA;Artificial Sequence> agcaacuacagac
<SEQ ID NO. 912;RNA;Artificial Sequence> gaccaaggucaac
<SEQ ID NO. 913;RNA;Artificial Sequence> cgacuaucucgac
<SEQ ID NO. 914;RNA;Artificial Sequence> aaccuucccaaac
<SEQ ID NO. 915;RNA;Artificial Sequence> ccaagcuuagaacu
<SEQ ID NO. 916;RNA;Artificial Sequence> agcuuagaacuuuaa
<SEQ ID NO. 917;RNA;Artificial Sequence> aagaccaccac
<SEQ ID NO. 918;RNA;Artificial Sequence> gcgagaaauaaagu
<SEQ ID NO. 919;RNA; Artificial Sequence> cgagaaauaaaguu
<SEQ ID NO. 920;RNA;Artificial Sequence> aggaaaugaucc
741-3602

CA 02677068 2009-09-01
<SEQ ID NO. 921;RNA;Artificial Sequence> gaagaaaugaaac
<SEQ ID NO. 922;RNA;Artificial Sequence> guuuccauccucc
<SEQ ID NO. 923;RNA;Artificial Sequence> acugaaaaucuuuga
<SEQ ID NO. 924;RNA;Artificial Sequence> ugccguucagg
<SEQ ID NO. 925;RNA;Artificial Sequence> caggguccagaag
<SEQ ID NO. 926;RNA;Artificial Sequence> ucaagacugcuug
<SEQ ID NO. 927;RNA;Artificial Sequence> uccaugucuuugg
<SEQ ID NO. 928;RNA;Artificial Sequence> gccugaaacac
<SEQ ID NO. 929;RNA;Artificial Sequence> ucucuguaccuc
<SEQ ID NO. 930;RNA;Artificial Sequence> agcaagacaaga
<SEQ ID NO. 931;RNA;Artificial Sequence> gcaagacaagaaa
<SEQ ID NO. 932;RNA;Artificial Sequence> uguacaagaucc
<SEQ ID NO. 933;RNA;Artificial Sequence> cguacuugcaga
<SEQ ID NO. 934;RNA;Artificial Sequence> cgaucgauacaga
<SEQ ID NO. 935;RNA;Artificial Sequence> uauaaaaauaaau
<SEQ ID NO. 936;RNA;Artificial Sequence> uaaaaauaaauau
<SEQ ID NO. 937;RNA;Artificial Sequence> uuugacugcugug
<SEQ ID NO. 938;RNA;Artificial Sequence> ggagaugagagac
<SEQ ID NO. 939;RNA;Artificial Sequence> ucccacuugg
<SEQ ID NO. 940;RNA;Artificial Sequence> guucacggcc
<SEQ ID NO. 941;RNA;Artificial Sequence> accaucacacca
<SEQ ID NO. 942;RNA;Artificial Sequence> cugcggguuu
<SEQ ID NO. 943;RNA;Artificial Sequence> uccaguuug
<SEQ ID NO. 944;RNA;Artificial Sequence> uuaaggacuucu
<SEQ ID NO. 945;RNA;Artificial Sequence> agugggacagag
<SEQ ID NO. 946;RNA;Artificial Sequence> auuuguuauugug
<SEQ ID NO. 947;RNA;Artificial Sequence> ucaaaugcauuu
<SEQ ID NO. 948;RNA;Artificial Sequence> aggaaagcc
<SEQ ID NO. 949;RNA;Artificial Sequence> ggaaagcccu
<SEQ ID NO. 950;RNA;Artificial Sequence> ccagcauggcc
<SEQ ID NO. 951;RNA;Artificial Sequence> uucucccuga
<SEQ ID NO. 952;RNA;Artificial Sequence> aagaagcccuu
<SEQ ID NO. 953;RNA;Artificial Sequence> gaagcccuuca
<SEQ ID NO. 954;RNA;Artificial Sequence> cccuucagcg
<SEQ ID NO. 955;RNA;Artificial Sequence> cuucagcggc
<SEQ ID NO. 956;RNA;Artificial Sequence> cagcggccagu
<SEQ ID NO. 957;RNA;Artificial Sequence> gaaaagcuccg
<SEQ ID NO. 958;RNA;Artificial Sequence> aaagcuccgg
<SEQ ID NO. 959;RNA;Artificial Sequence> gucaacagucug
<SEQ ID NO.960;RNA;Artiicial Sequence> agaguucaaaag
<SEQ ID NO. 961;RNA;Artificial Sequence> gaguucaaaagc
<SEQ ID NO. 962;RNA;Artificial Sequence> ucaaaagcccu
<SEQ ID NO. 963;RNA;Artificial Sequence> caaaagcccuu
<SEQ ID NO. 964;RNA;Artificial Sequence> aaagcccuuca
<SEQ ID NO. 965;RNA;Artificial Sequence> aagcccuucag
<SEQ ID NO. 966;RNA;Artificial Sequence> ugaagccgcucg
<SEQ ID NO. 967;RNA;Artificial Sequence> acgccagucaa
<SEQ ID NO.968;RNA;Artificial Sequence> ucuuggugcgug
<SEQ ID NO. 969;RNA;Artificial Sequence> uuggauucaucag
<SEQ ID NO.970;RNA;Artificial Sequence> ggaauaccuaag
<SEQ ID NO. 971;RNA;Artificial Sequence> uuugaggcuca
<SEQ ID NO. 972;RNA;Artificial Sequence> cuacaauugg
<SEQ ID NO. 973;RNA;Artificial Sequence> aguuaggagcc
<SEQ ID NO. 974;RNA;Artificial Sequence> gucaauauccac
<SEQ ID NO. 975;RNA;Artificial Sequence> uguucagucaca
<SEQ ID NO. 976;RNA; Artificial Sequence> cacacacauac
<SEQ ID NO. 977;RNA;Artificial Sequence> uccuuuugcuu
<SEQ ID NO. 978;RNA;Artificial Sequence> uuuaaaguaauuuuu
<SEQ ID NO. 979;RNA; Artificial Sequence> aacagucaaugg
<SEQ ID NO. 980;RNA;Artificial Sequence> cgacaaaccaau
<SEQ ID NO. 981;RNA;Artificial Sequence> cugcuaccacu
<SEQ ID NO. 982;RNA;Artificial Sequence> caagcggucuua
<SEQ ID NO. 983;RNA;Artificial Sequence> gucuuaccggcu
<SEQ ID NO. 984;RNA;Artificial Sequence> auggguuacc
<SEQ ID NO. 985;RNA;Artificial Sequence> uuaccugcga
<SEQ ID NO. 986;RNA;Artificial Sequence> aucuugcugag
<SEQ ID NO. 987;RNA;Artificial Sequence> gcauaaaacagu
<SEQ ID NO. 988;RNA;Artificial Sequence> uccuuuauccu
<SEQ ID NO. 989;RNA;Artificial Sequence> aacgcaaguug
<SEQ ID NO. 990;RNA;Artificial Sequence> aacugaaaccau
<SEQ ID NO. 991;RNA;Artificial Sequence> cuuuguuaaauau
<SEQ ID NO. 992;RNA;Artificial Sequence> uauauuaaaaguu
<SEQ ID NO. 993;RNA;Artificial Sequence> uuuugacuuaac
741-3603

CA 02677068 2009-09-01
<SEQ ID NO. 994;RNA;Artificial Sequence> caaacucagcac
<SEQ ID NO. 995;RNA;Artificial Sequence> gcugaccuca
<SEQ ID NO. 996;RNA;Artificial Sequence> uuauucagaucgc
<SEQ ID NO. 997;RNA;Artificial Sequence> ggguucugggau
<SEQ ID NO. 998;RNA;Artificial Sequence> uauuggaaauuaug
<SEQ ID NO. 999;RNA;Artificial Sequence> uggaagcacuag
<SEQ ID NO. 1000;RNA;Artificial Sequence> uuuuuaugugga
<SEQ ID NO. 1001;RNA;Artificial Sequence> gaauugguaga
<SEQ ID NO. 1002;RNA;Artificial Sequence> uagacuuggaga
<SEQ ID NO. 1003;RNA;Artificial Sequence> uacaguauucca
<SEQ ID NO. 1004;RNA;Artificial Sequence> cacugaugaauuaa
<SEQ ID NO. 1005;RNA;Artificial Sequence> cacaucaucac
<SEQ ID NO. 1006;RNA;Artificial Sequence> ucaccaaacaga
<SEQ ID NO. 1007;RNA;Artificial Sequence> gaacaugaugg
<SEQ ID NO. 1008;RNA;Artificial Sequence> auguagacugc
<SEQ ID NO. 1009;RNA;Artificial Sequence> gaucuauuuaug
<SEQ ID NO. 1010;RNA;Artificial Sequence> cacuauuauca
<SEQ ID NO. 1011;RNA;Artificial Sequence> ucaguucugc
<SEQ ID NO. 1012;RNA;Artificial Sequence> gauuaaaccuac
<SEQ ID NO. 1013;RNA;Artificial Sequence> uaaaauccuucu
<SEQ ID NO. 1014;RNA;Artificial Sequence> augcuguagac
<SEQ ID NO. 1015;RNA;Artificial Sequence> ugauaggaauag
<SEQ ID NO. 1016;RNA;Artificial Sequence> auggcccuga
<SEQ ID NO. 1017;RNA;Artificial Sequence> uccucaagca
<SEQ ID NO. 1018;RNA;Artificial Sequence> uucagccca
<SEQ ID NO. 1019;RNA;Artificial Sequence> cugcugaacc
<SEQ ID NO. 1020;RNA;Artificial Sequence> aguucucuuca
<SEQ ID NO. 1021;RNA;Artificial Sequence> cagccuagag
<SEQ ID NO. 1022;RNA;Artificial Sequence> ucugugaagugu
<SEQ ID NO. 1023;RNA;Artificial Sequence> gagaaaauuucaa
<SEQ ID NO. 1024;RNA;Artificial Sequence> auccuccuga
<SEQ ID NO. 1025;RNA;Artificial Sequence> ugacaucauau
<SEQ ID NO. 1026;RNA;Artificial Sequence> aucuucaucaua
<SEQ ID NO. 1027;RNA;Artificial Sequence> acuagcuauuaa
<SEQ ID NO. 1028;RNA;Artificial Sequence> cucuacuaaaaau
<SEQ ID NO. 1029;RNA;Artificial Sequence> cuaucucgccu
<SEQ ID NO. 1030;RNA;Artificial Sequence> uucgguccaguu
<SEQ ID NO. 1031;RNA;Artificial Sequence> auguagccgc
<SEQ ID NO. 1032;RNA;Artificial Sequence> gaggagacuug
<SEQ ID NO. 1033;RNA;Artificial Sequence> aguagugagga
<SEQ ID NO. 1034;RNA;Artificial Sequence> agaugaguacaaa
<SEQ ID NO. 1035;RNA;Artificial Sequence> uuguuaaugggc
<SEQ ID NO. 1036;RNA;Artificial Sequence> uuuuaauuuauu
<SEQ ID NO. 1037;RNA;Artificial Sequence> auuuaaauaug
<SEQ ID NO. 1038;RNA;Artificial Sequence> auccuuuguuuc
<SEQ ID NO. 1039;RNA;Artificial Sequence> gucuaaguguuug
<SEQ ID NO. 1040;RNA;Artificial Sequence> ccugugacaaa
<SEQ ID NO. 1041;RNA;Artificial Sequence> caggcugaauua
<SEQ ID NO. 1042;RNA;Artificial Sequence> ucauucuuacaau
<SEQ ID NO. 1043;RNA;Artificial Sequence> cauucuuacaauug
<SEQ ID NO. 1044;RNA;Artificial Sequence> agagaguguac
<SEQ ID NO. 1045;RNA;Artificial Sequence> gaacucagcag
<SEQ ID NO. 1046;RNA;Artificial Sequence> uuauuuucagua
<SEQ ID NO. 1047;RNA;Artificial Sequence> cuuaaauggaa
<SEQ ID NO. 1048;RNA;Artificial Sequence> gccuaaaauugu
<SEQ ID NO. 1049;RNA;Artificial Sequence> acuaacaucugg
<SEQ ID NO. 1050;RNA;Artificial Sequence> gacugugagcu
<SEQ ID NO. 1051;RNA;Artificial Sequence> gcuuuuuauuaau
<SEQ ID NO. 1052;RNA;Artificial Sequence> ucuucuuacauu
<SEQ ID NO. 1053;RNA;Artificial Sequence> auuuguaaaaaugu
<SEQ ID NO. 1054;RNA;Artificial Sequence> ucuuaauucauauu
<SEQ ID NO. 1055;RNA;Artificial Sequence> aacuaaucauga
<SEQ ID NO. 1056;RNA;Artificial Sequence> cugcucuuggg
<SEQ ID NO. 1057;RNA;Artificial Sequence> aguagcuuugag
<SEQ ID NO. 1058;RNA;Artificial Sequence> acguaauauuuca
<SEQ ID NO. 1059;RNA;Artificial Sequence> auucucuucacu
<SEQ ID NO. 1060;RNA;Artificial Sequence> uaaugcuaagaaa
<SEQ ID NO. 1061;RNA;Artificial Sequence> cugaaaaucaa
<SEQ ID NO. 1062;RNA;Artificial Sequence> auaugauuacuuu
<SEQ ID NO. 1063;RNA;Artificial Sequence> auuuuguucuaca
<SEQ ID NO. 1064;RNA;Artificial Sequence> ccgggacucuc
<SEQ ID NO. 1065;RNA;Artificial Sequence> cuuuaaaguaaag
<SEQ ID NO. 1066;RNA;Artificial Sequence> cuggaagccugg
741-3604

CA 02677068 2009-09-01
<SEQ ID NO. 1067;RNA;Artificial Sequence> aaacaaaagagag
<SEQ ID NO. 1068;RNA;Artificial Sequence> ucaguuaugccg
<SEQ ID NO. 1069;RNA;Artificial Sequence> aaaagaagucca
<SEQ ID NO. 1070;RNA;Artificial Sequence> ggugagguua
<SEQ ID NO. 1071;RNA;Artificial Sequence> ggaagaggac
<SEQ ID NO. 1072;RNA;Artificial Sequence> agcaaguauugu
<SEQ ID NO. 1073;RNA;Artificial Sequence> uuguagcacuc
<SEQ ID NO. 1074;RNA;Artificial Sequence> caaaaccacaaau
<SEQ ID NO. 1075;RNA;Artificial Sequence> aagcccauaca
<SEQ ID NO. 1076;RNA;Artificial Sequence> gcccauacag
<SEQ ID NO. 1077;RNA;Artificial Sequence> agaaaccuucc
<SEQ ID NO. 1078;RNA;Artificial Sequence> uauaccuac
<SEQ ID NO. 1079;RNA;Artificial Sequence> ccaguuuucgga
<SEQ ID NO. 1080;RNA;Artificial Sequence> gaacaggg
<SEQ ID NO. 1081;RNA;Artificial Sequence> uaacuuuccagu
<SEQ ID NO. 1082;RNA;Artificial Sequence> aaguuugguuuug
<SEQ ID NO. 1083;RNA;Artificial Sequence> uucccacugua
<SEQ ID NO. 1084;RNA;Artificial Sequence> gauaccauauga
<SEQ ID NO. 1085;RNA;Artificial Sequence> acaugggcug
<SEQ ID NO. 1086;RNA;Artificial Sequence> aacuuuuucaua
<SEQ ID NO. 1087;RNA;Artificial Sequence> augaggccgga
<SEQ ID NO. 1088;RNA;Artificial Sequence> cugcauuugu
<SEQ ID NO. 1089;RNA;Artificial Sequence> auguuuacuacc
<SEQ ID NO. 1090;RNA;Artificial Sequence> auuuuuugaugaaa
<SEQ ID NO. 1091;RNA;Artificial Sequence> agugugugaauuu
<SEQ ID NO. 1092;RNA;Artificial Sequence> agcaauguaugu
<SEQ ID NO. 1093;RNA;Artificial Sequence> aagcacauauaua
<SEQ ID NO. 1094;RNA;Artificial Sequence> uaauaguuucucc
<SEQ ID NO. 1095;RNA;Artificial Sequence> guuucuccaaau
<SEQ ID NO. 1096;RNA;Artificial Sequence> acuuccuagaaa
<SEQ ID NO. 1097;RNA;Artificial Sequence> acaccauauaug
<SEQ ID NO. 1098;RNA;Artificial Sequence> uauaugaauggag
<SEQ ID NO. 1099;RNA;Artificial Sequence> cauuuacaggga
<SEQ ID NO. 1100;RNA;Artificial Sequence> auuuacagggac
<SEQ ID NO. 1101;RNA;Artificial Sequence> gggaccuga
<SEQ ID NO. 1102;RNA;Artificial Sequence> guuugacugcauc
<SEQ ID NO. 1103;RNA;Artificial Sequence> uugacugcaucg
<SEQ ID NO. 1104;RNA;Artificial Sequence> aguucacaggg
<SEQ ID NO. 1105;RNA;Artificial Sequence> gcaccucugucc
<SEQ ID NO. 1106;RNA;Artificial Sequence> guuugucuuuuuaa
<SEQ ID NO. 1107;RNA;Artificial Sequence> uugucuuuuuaag
<SEQ ID NO. 1108;RNA;Artificial Sequence> cuaaagguuguc
<SEQ ID NO. 1109;RNA;Artificial Sequence> agguugucgac
<SEQ ID NO. 1110;RNA;Artificial Sequence> ccuggcaauugu
<SEQ ID NO. 1111;RNA;Artificial Sequence> guggugcgagg
<SEQ ID NO. 11 12;RNA;Artificial Sequence> gagacaugaaau
<SEQ ID NO. 11 13;RNA;Artificial Sequence> uauauuucucca
<SEQ ID NO. 11 14;RNA;Artificial Sequence> augaaggcu
<SEQ ID NO. 1115;RNA;Artificial Sequence> cuggaguggu
<SEQ ID NO. 11 16;RNA;Artificial Sequence> ggaagagagg
<SEQ ID NO. 11 17;RNA;Artificial Sequence> uugcaucgggc
<SEQ ID NO. 1118;RNA;Artificial Sequence> uauccuacugug
<SEQ ID NO. 11 19;RNA;Artificial Sequence> ccuacuguguaa
<SEQ ID NO. 1120;RNA;Artificial Sequence> cuuguagugua
<SEQ ID NO. 1121;RNA;Artificial Sequence> cuuuguugauug
<SEQ ID NO. 1122;RNA;Artificial Sequence> uuguugauugaaa
<SEQ ID NO. 1123;RNA;Artificial Sequence> ucuuuuucuuccau
<SEQ ID NO. 1124;RNA;Artificial Sequence> aucuuccuucua
<SEQ ID NO. 1125;RNA;Artificial Sequence> ugaaugcuucau
<SEQ ID NO. 1126;RNA;Artificial Sequence> gaaugcuucaug
<SEQ ID NO. 1127;RNA;Artificial Sequence> auucuacuuuga
<SEQ ID NO. 1128;RNA;Artificial Sequence> gcaacuacagac
<SEQ ID NO. 1129;RNA;Artificial Sequence> accaaggucaac
<SEQ ID NO. 1130;RNA;Artificial Sequence> gacuaucucgac
<SEQ ID NO. 1131;RNA;Artificial Sequence> accuucccaaac
<SEQ ID NO. 1132;RNA;Artificial Sequence> caagcuuagaacu
<SEQ ID NO. 1133;RNA;Artificial Sequence> gcuuagaacuuuaa
<SEQ ID NO. 11 34;RNA;Artificial Sequence> aacuuuaagcaac
<SEQ ID NO. 1135;RNA;Artificial Sequence> agaccaccac
<SEQ ID NO. 1136;RNA;Artificial Sequence> cgagaaauaaagu
<SEQ ID NO. 1137;RNA;Artificial Sequence> gagaaauaaaguu
<SEQ ID NO. 1138;RNA;Artificial Sequence> ggaaaugaucc
<SEQ ID NO. 1139;RNA;Artificial Sequence> aagaaaugaaac
741-3605

CA 02677068 2009-09-01
<SEQ ID NO. 1140;RNA;Artificial Sequence> uuuccauccucc
<SEQ ID NO. 1141;RNA;Artificial Sequence> cugaaaaucuuuga
<SEQ ID NO. 1142;RNA;Artificial Sequence> gccguucagg
<SEQ ID NO. 1143;RNA;Artificial Sequence> aggguccagaag
<SEQ ID NO. 1144;RNA;Artificial Sequence> caagacugcuug
<SEQ ID NO. 1145;RNA;Artificial Sequence> ccaugucuuugg
<SEQ ID NO. 1146;RNA;Artificial Sequence> ccugaaacac
<SEQ ID NO. 1147;RNA;Artificial Sequence> cucuguaccuc
<SEQ ID NO. 1148;RNA;Artificial Sequence> gcaagacaaga
<SEQ ID NO. 1149;RNA;Artificial Sequence> caagacaagaaa
<SEQ ID NO. 1150;RNA;Artificial Sequence> guacaagaucc
<SEQ ID NO. 1151;RNA;Artificial Sequence> guacuugcaga
<SEQ ID NO. I152;RNA;Artificial Sequence> gaucgauacaga
<SEQ ID NO. 1153;RNA;Artificial Sequence> auaaaaauaaau
<SEQ ID NO. 1154;RNA;Artificial Sequence> aaaaauaaauau
<SEQ ID NO. 1155;RNA;Artificial Sequence> uugacugcugug
<SEQ ID NO. 1156;RNA;Artificial Sequence> gagaugagagac
<SEQ ID NO. 1157;RNA;Artificial Sequence> cccacuugg
<SEQ ID NO. 1158;RNA;Homo sapiens>
GUGAUGCGUAGUUCCGGCUGCCGGUUGACAUGAAGAAGCAGCAGCGGCUAGGGCGGCGGUAGCUGCAGGG
GUCGGGGAUUGCAGCGGGCCUCGGGGCUAAGAGCGCGACGCGGCCUAGAGCGGCAGACGGCGCAGUGGGCCGAGAAG
GAGGCGCAGCAGCCGCCCUGGCCCGUCAUGGAGAUGGAAAAGGAGUUCGAGCAGAUCGACAAGUCCGGGAGCUGGGC
GGCCAUUUACCAGGAUAUCCGACAUGAAGCCAGUGACUUCCCAUGUAGAGUGGCCAAGCUUCCUAAGAACAAAAACC
GAAAUAGGUACAGAGACGUCAGUCCCUUUGACCAUAGUCGGAUUAAACUACAUCAAGAAGAUAAUGACUAUAUCAA
CGCUAGUUUGAUAAAAAUGGAAGAAGCCCAAAGGAGUUACAUUCUUACCCAGGGCCCUUUGCCUAACACAUGCGGUC
ACUUUUGGGAGAUGGUGUGGGAGCAGAAAAGCAGGGGUGUCGUCAUGCUCAACAGAGUGAUGGAGAAAGGUUCGUU
AAAAUGCGCACAAUACUGGCCACAAAAAGAAGAAAAAGAGAUGAUCUUUGAAGACACAAAUUUGAAAUUAACAUUG
AUCUCUGAAGAUAUCAAGUCAUAUUAUACAGUGCGACAGCUAGAAUUGGAAAACCUUACAACCCAAGAAACUCGAG
AGAUCUUACAUUUCCACUAUACCACAUGGCCUGACUUUGGAGUCCCUGAAUCACCAGCCUCAUUCUUGAACUUUCUU
UUCAAAGUCCGAGAGUCAGGGUCACUCAGCCCGGAGCACGGGCCCGUUGUGGUGCACUGCAGUGCAGGCAUCGGCAG
GUCUGGAACCUUCUGUCUGGCUGAUACCUGCCUCUUGCUGAUGGACAAGAGGAAAGACCCUUCUUCCGUUGAUAUCA
AGAAAGUGCUGUUAGAAAUGAGGAAGUUUCGGAUGGGGCUGAUCCAGACAGCCGACCAGCUGCGCUUCUCCUACCUG
GCUGUGAUCGAAGGUGCCAAAUUCAUCAUGGGGGACUCUUCCGUGCAGGAUCAGUGGAAGGAGCUUUCCCACGAGG
ACCUGGAGCCCCCACCCGAGCAUAUCCCCCCACCUCCCCGGCCACCCAAACGAAUCCUGGAGCCACACAAUGGGAAAU
GCAGGGAGUUCUUCCCAAAUCACCAGUGGGUGAAGGAAGAGACCCAGGAGGAUAAAGACUGCCCCAUCAAGGAAGA
AAAAGGAAGCCCCUUAAAUGCCGCACCCUACGGCAUCGAAAGCAUGAGUCAAGACACUGAAGUUAGAAGUCGGGUCG
UGGGGGGAAGUCUUCGAGGUGCCCAGGCUGCCUCCCCAGCCAAAGGGGAGCCGUCACUGCCCGAGAAGGACGAGGAC
CAUGCACUGAGUUACUGGAAGCCCUUCCUGGUCAACAUGUGCGUGGCUACGGUCCUCACGGCCGGCGCUUACCUCUG
CUACAGGUUCCUGUUCAACAGCAACACAUAGCCUGACCCUCCUCCACUCCACCUCCACCCACUGUCCGCCUCUGCCCG
CAGAGCCCACGCCCGACUAGCAGGCAUGCCGCGGUAGGUAAGGGCCGCCGGACCGCGUAGAGAGCCGGGCCCCGGAC
GGACGUUGGUUCUGCACUAAAACCCAUCUUCCCCGGAUGUGUGUCUCACCCCUCAUCCUUUUACUUUUUGCCCCUUC
CACUUUGAGUACCAAAUCCACAAGCCAUUUUUUGAGGAGAGUGAAAGAGAGUACCAUGCUGGCGGCGCAGAGGGAA
GGGGCCUACACCCGUCUUGGGGCUCGCCCCACCCAGGGCUCCCUCCUGGAGCAUCCCAGGCGGGCGGCACGCCAACAG
CCCCCCCCUUGAAUCUGCAGGGAGCAACUCUCCACUCCAUAUUUAUUUAAACAAUUUUUUCCCCAAAGGCAUCCAUA
GUGCACUAGCAUUUUCUUGAACCAAUAAUGUAUUAAAAUUUUUUGAUGUCAGCCUUGCAUCAAGGGCUUUAUCAAA
AAGUACAAUAAUAAAUCCUCAGGUAGUACUGGGAAUGGAAGGCUUUGCCAUGGGCCUGCUGCGUCAGACCAGUACU
GGGAAGGAGGACGGUUGUAAGCAGUUGUUAUUUAGUGAUAUUGUGGGUAACGUGAGAAGAUAGAACAAUGCUAUAA
UAUAUAAUGAACACGUGGGUAUUUAAUAAGAAACAUGAUGUGAGAUUACUUUGUCCCGCUUAUUCUCCUCCCUGUU
AUCUGCUAGAUCUAGUUCUCAAUCACUGCUCCCCCGUGUGUAUUAGAAUGCAUGUAAGGUCUUCUUGUGUCCUGAUG
AAAAAUAUGUGCUUGAAAUGAGAAACUUUGAUCUCUGCUUACUAAUGUGCCCCAUGUCCAAGUCCAACCUGCCUGUG
CAUGACCUGAUCAUUACAUGGCUGUGGUUCCUAAGCCUGUUGCUGAAGUCAUUGUCGCUCAGCAAUAGGGUGCAGU
UUUCCAGGAAUAGGCAUUUGCCUAAUUCCUGGCAUGACACUCUAGUGACUUCCUGGUGAGGCCCAGCCUGUCCUGGU
ACAGCAGGGUCUUGCUGUAACUCAGACAUUCCAAGGGUAUGGGAAGCCAUAUUCACACCUCACGCUCUGGACAUGAU
UUAGGGAAGCAGGGACACCCCCCGCCCCCCACCUUUGGGAUCAGCCUCCGCCAUUCCAAGUCAACACUCUUCUUGAGC
AGACCGUGAUUUGGAAGAGAGGCACCUGCUGGAAACCACACUUCUUGAAACAGCCUGGGUGACGGUCCUUUAGGCAG
CCUGCCGCCGUCUCUGUCCCGGUUCACCUUGCCGAGAGAGGCGCGUCUGCCCCACCCUCAAACCCUGUGGGGCCUGAU
GGUGCUCACGACUCUUCCUGCAAAGGGAACUGAAGACCUCCACAUUAAGUGGCUUUUUAACAUGAAAAACACGGCAG
CUGUAGCUCCCGAGCUACUCUCUUGCCAGCAUUUUCACAUUUUGCCUUUCUCGUGGUAGAAGCCAGUACAGAGAAAU
UCUGUGGUGGGAACAUUCGAGGUGUCACCCUGCAGAGCUAUGGUGAGGUGUGGAUAAGGCUUAGGUGCCAGGCUGU
AAGCAUUCUGAGCUGGGCUUGUUGUUUUUAAGUCCUGUAUAUGUAUGUAGUAGUUUGGGUGUGUAUAUAUAGUAGC
AUUUCAAAAUGGACGUACUGGUUUAACCUCCUAUCCUUGGAGAGCAGCUGGCUCUCCACCUUGUUACACAUUAUGUU
AGAGAGGUAGCGAGCUGCUCUGCUAUAUGCCUUAAGCCAAUAUUUACUCAUCAGGUCAUUAUUUUUUACAAUGGCC
AUGGAAUAAACCAUUUUUACAAAA
<SEQ ID NO. 1159;RNA;Artificial Sequence> gugaugcguaguuccggcu
<SEQ ID NO. 1160;RNA;Artificial Sequence> ugccgguugacaugaagaa
<SEQ ID NO. 1161;RNA;Artificial Sequence> agcagcagcggcuagggcg
<SEQ ID NO. 1162;RNA;Artificial Sequence> ggcgguagcugcagggguc
<SEQ ID NO. 1163;RNA;Artificial Sequence> cggggauugcagcgggccu
<SEQ ID NO. 1164;RNA;Artificial Sequence> ucggggcuaagagcgcgac
<SEQ ID NO. 1165;RNA;Artificial Sequence> cgcggccuagagcggcaga
<SEQ ID NO. 1166;RNA;Artificial Sequence> acggcgcagugggccgaga
<SEQ ID NO. I 167;RNA;Artificial Sequence> aaggaggcgcagcagccgc
<SEQ ID NO. 1168;RNA;Artificial Sequence> cccuggcccgucauggaga
741-3606

CA 02677068 2009-09-01
<SEQ ID NO. 1169;RNA;Artificial Sequence> auggaaaaggaguucgagc
<SEQ ID NO. 1170;RNA;Artificial Sequence> cagaucgacaaguccggga
<SEQ ID NO. 1171;RNA;Artificial Sequence> agcugggcggccauuuacc
<SEQ ID NO. 1172;RNA;Artificial Sequence> caggauauccgacaugaag
<SEQ ID NO. 1173;RNA;Artificial Sequence> gccagugacuucccaugua
<SEQ ID NO. 1174;RNA;Artificial Sequence> agaguggccaagcuuccua
<SEQ ID NO. 1175;RNA;Artificial Sequence> aagaacaaaaaccgaaaua
<SEQ ID NO. 1176;RNA;Artificial Sequence> agguacagagacgucaguc
<SEQ ID NO. 1177;RNA;Artificial Sequence> cccuuugaccauagucgga
<SEQ ID NO. 1178;RNA;Artificial Sequence> auuaaacuacaucaagaag
<SEQ ID NO. 1179;RNA;Artificial Sequence> gauaaugacuauaucaacg
<SEQ ID NO. 11 80;RNA;Artificial Sequence> gcuaguuugauaaaaaugg
<SEQ ID NO. 1181;RNA;Artificial Sequence> gaagaagcccaaaggaguu
<SEQ ID NO. 1182;RNA;Artificial Sequence> uacauucuuacccagggcc
<SEQ ID NO. 1183;RNA;Artificial Sequence> ccuuugccuaacacaugcg
<SEQ ID NO. 11 84;RNA;Artificial Sequence> ggucacuuuugggagaugg
<SEQ ID NO. 1185;RNA;Artificial Sequence> gugugggagcagaaaagca
<SEQ ID NO. 1186;RNA;Artificial Sequence> aggggugucgucaugcuca
<SEQ ID NO. 1187;RNA;Artificial Sequence> aacagagugauggagaaag
<SEQ ID NO. 1188;RNA;Artificial Sequence> gguucguuaaaaugcgcac
<SEQ ID NO. 1189;RNA;Artificial Sequence> caauacuggccacaaaaag
<SEQ ID NO. 1190;RNA;Artificial Sequence> gaagaaaaagagaugaucu
<SEQ ID NO. 1191;RNA;Artificial Sequence> uuugaagacacaaauuuga
<SEQ ID NO. 1192;RNA;Artificial Sequence> aaauuaacauugaucucug
<SEQ ID NO. 1193;RNA;Artificial Sequence> gaagauaucaagucauauu
<SEQ ID NO. 1194;RNA;Artificial Sequence> uauacagugcgacagcuag
<SEQ ID NO. 1195;RNA;Artificial Sequence> gaauuggaaaaccuuacaa
<SEQ ID NO. 1196;RNA;Artificial Sequence> acccaagaaacucgagaga
<SEQ ID NO. 1197;RNA;Artificial Sequence> aucuuacauuuccacuaua
<SEQ ID NO. 1198;RNA;Artificial Sequence> accacauggccugacuuug
<SEQ ID NO. 1199;RNA;Artificial Sequence> ggagucccugaaucaccag
<SEQ ID NO. 1200;RNA;Artificial Sequence> gccucauucuugaacuuuc
<SEQ ID NO. 1201;RNA;Artificial Sequence> cuuuucaaaguccgagagu
<SEQ ID NO. 1202;RNA;Artificial Sequence> ucagggucacucagcccgg
<SEQ ID NO. 1203;RNA;Artificial Sequence> gagcacgggcccguugugg
<SEQ ID NO. 1204;RNA;Artificial Sequence> gugcacugcagugcaggca
<SEQ ID NO. 1205;RNA;Artificial Sequence> aucggcaggucuggaaccu
<SEQ ID NO. 1206;RNA;Artificial Sequence> uucugucuggcugauaccu
<SEQ ID NO. 1207;RNA;Artificial Sequence> ugccucuugcugauggaca
<SEQ ID NO. 1208;RNA;Artificial Sequence> aagaggaaagacccuucuu
<SEQ ID NO. 1209;RNA;Artificial Sequence> uccguugauaucaagaaag
<SEQ ID NO. 1210;RNA;Artificial Sequence> gugcuguuagaaaugagga
<SEQ ID NO. 1211;RNA;Artificial Sequence> aaguuucggauggggcuga
<SEQ ID NO. 1212;RNA;Artificial Sequence> auccagacagccgaccagc
<SEQ ID NO. 1213;RNA;Artificial Sequence> cugcgcuucuccuaccugg
<SEQ ID NO. 1214;RNA;Artificial Sequence> gcugugaucgaaggugcca
<SEQ ID NO. 1215;RNA;Artificial Sequence> aaauucaucaugggggacu
<SEQ ID NO. 1216;RNA;Artificial Sequence> ucuuccgugcaggaucagu
<SEQ ID NO. 1217;RNA;Artificial Sequence> uggaaggagcuuucccacg
<SEQ ID NO. 1218;RNA;Artificial Sequence> gaggaccuggagcccccac
<SEQ ID NO. 1219;RNA;Artificial Sequence> cccgagcauauccccccac
<SEQ ID NO. 1220;RNA;Artificial Sequence> ccuccccggccacccaaac
<SEQ ID NO. 1221;RNA;Artificial Sequence> cgaauccuggagccacaca
<SEQ ID NO. 1222;RNA;Artificial Sequence> aaugggaaaugcagggagu
<SEQ ID NO. 1223;RNA;Artificial Sequence> uucuucccaaaucaccagu
<SEQ ID NO. I224;RNA;Artificial Sequence> ugggugaaggaagagaccc
<SEQ ID NO. 1225;RNA;Artificial Sequence> caggaggauaaagacugcc
<SEQ ID NO. 1226;RNA;Artificial Sequence> cccaucaaggaagaaaaag
<SEQ ID NO. 1227;RNA;Artificial Sequence> ggaagccccuuaaaugccg
<SEQ ID NO. 1228;RNA;Artificial Sequence> gcacccuacggcaucgaaa
<SEQ ID NO. 1229;RNA;Artificial Sequence> agcaugagucaagacacug
<SEQ ID NO. 1230;RNA;Artificial Sequence> gaaguuagaagucgggucg
<SEQ ID NO. 1231;RNA;Artificial Sequence> guggggggaagucuucgag
<SEQ ID NO. 1232;RNA;Artificial Sequence> ggugcccaggcugccuccc
<SEQ ID NO. 1233;RNA;Artificial Sequence> ccagccaaaggggagccgu
<SEQ ID NO. 1234;RNA;Artificial Sequence> ucacugcccgagaaggacg
<SEQ ID NO. 1235;RNA;Artificial Sequence> gaggaccaugcacugaguu
<SEQ ID NO. 1236;RNA;Artificial Sequence> uacuggaagcccuuccugg
<SEQ ID NO. 1237;RNA;Artificial Sequence> gucaacaugugcguggcua
<SEQ ID NO. 1238;RNA;Artificial Sequence> acgguccucacggccggcg
<SEQ ID NO. 1239;RNA;Artificial Sequence> gcuuaccucugcuacaggu
<SEQ ID NO. 1240;RNA;Artificial Sequence> uuccuguucaacagcaaca
<SEQ ID NO. 1241;RNA;Artificial Sequence> acauagccugacccuccuc
741-3607

CA 02677068 2009-09-01
<SEQ ID NO. 1242;RNA;Artificial Sequence> ccacuccaccuccacccac
<SEQ ID NO. 1243;RNA;Artificial Sequence> cuguccgccucugcccgca
<SEQ ID NO. 1244;RNA;Artificial Sequence> agagcccacgcccgacuag
<SEQ ID NO. 1245;RNA;Artificial Sequence> gcaggcaugccgcgguagg
<SEQ ID NO. 1246;RNA;Artificial Sequence> guaagggccgccggaccgc
<SEQ ID NO. 1247;RNA;Artificial Sequence> cguagagagccgggccccg
<SEQ ID NO. 1248;RNA;Artificial Sequence> ggacggacguugguucugc
<SEQ ID NO. 1249;RNA;Artificial Sequence> cacuaaaacccaucuuccc
<SEQ ID NO. 1250;RNA;Artificial Sequence> ccggaugugugucucaccc
<SEQ ID NO. 1251;RNA;Artificial Sequence> ccucauccuuuuacuuuuu
<SEQ ID NO. 1252;RNA;Artificial Sequence> ugccccuuccacuuugagu
<SEQ ID NO. 1253;RNA;Artificial Sequence> uaccaaauccacaagccau
<SEQ ID NO. 1254;RNA;Artificial Sequence> uuuuuugaggagagugaaa
<SEQ ID NO. 1255;RNA;Artificial Sequence> agagaguaccaugcuggcg
<SEQ ID NO. 1256;RNA;Artificial Sequence> ggcgcagagggaaggggcc
<SEQ ID NO. 1257;RNA;Artificial Sequence> cuacacccgucuuggggcu
<SEQ ID NO. 1258;RNA;Artificial Sequence> ucgccccacccagggcucc
<SEQ ID NO. 1259;RNA;Artificial Sequence> ccuccuggagcaucccagg
<SEQ ID NO. 1260;RNA;Artificial Sequence> gcgggcggcacgccaacag
<SEQ ID NO. 1261;RNA;Artificial Sequence> gccccccccuugaaucugc
<SEQ ID NO. 1262;RNA;Artificial Sequence> cagggagcaacucuccacu
<SEQ ID NO. 1263;RNA;Artificial Sequence> uccauauuuauuuaaacaa
<SEQ ID NO. 1264;RNA;Artificial Sequence> auuuuuuccccaaaggcau
<SEQ ID NO. 1265;RNA;Artificial Sequence> uccauagugcacuagcauu
<SEQ ID NO. 1266;RNA;Artificial Sequence> uuucuugaaccaauaaugu
<SEQ ID NO. 1267;RNA;Artificial Sequence> uauuaaaauuuuuugaugu
<SEQ ID NO. 1268;RNA;Artificial Sequence> ucagccuugcaucaagggc
<SEQ ID NO. 1269;RNA;Artificial Sequence> cuuuaucaaaaaguacaau
<SEQ ID NO. 1270;RNA;Artificial Sequence> uaauaaauccucagguagu
<SEQ ID NO. 1271;RNA;Artificial Sequence> uacugggaauggaaggcuu
<SEQ ID NO. 1272;RNA;Artificial Sequence> uugccaugggccugcugcg
<SEQ ID NO. 1273;RNA;Artificial Sequence> gucagaccaguacugggaa
<SEQ ID NO. 1274;RNA;Artificial Sequence> aggaggacgguuguaagca
<SEQ ID NO. 1275;RNA;Artificial Sequence> aguuguuauuuagugauau
<SEQ ID NO. 1276;RNA;Artificial Sequence> uuguggguaacgugagaag
<SEQ ID NO. 1277;RNA;Artificial Sequence> gauagaacaaugcuauaau
<SEQ ID NO. 1278;RNA;Artificial Sequence> uauauaaugaacacguggg
<SEQ ID NO. 1279;RNA;Artificial Sequence> guauuuaauaagaaacaug
<SEQ ID NO. 1280;RNA;Artificial Sequence> gaugugagauuacuuuguc
<SEQ ID NO. 1281;RNA;Artificial Sequence> cccgcuuauucuccucccu
<SEQ ID NO. 1282;RNA;Artificial Sequence> uguuaucugcuagaucuag
<SEQ ID NO. 1283;RNA;Artificial Sequence> guucucaaucacugcuccc
<SEQ ID NO. 1284;RNA;Artificial Sequence> cccguguguauuagaaugc
<SEQ ID NO. 1285;RNA;Artificial Sequence> cauguaaggucuucuugug
<SEQ ID NO. 1286;RNA;Artificial Sequence> guccugaugaaaaauaugu
<SEQ ID NO. 1287;RNA;Artificial Sequence> ugcuugaaaugagaaacuu
<SEQ ID NO. 1288;RNA;Artificial Sequence> uugaucucugcuuacuaau
<SEQ ID NO. 1289;RNA;Artificial Sequence> ugugccccauguccaaguc
<SEQ ID NO. 1290;RNA;Artificial Sequence> ccaaccugccugugcauga
<SEQ ID NO. 1291;RNA;Artificial Sequence> accugaucauuacauggcu
<SEQ ID NO. 1292;RNA;Artificial Sequence> ugugguuccuaagccuguu
<SEQ ID NO. 1293;RNA;Artificial Sequence> ugcugaagucauugucgcu
<SEQ ID NO. 1294;RNA;Artificial Sequence> ucagcaauagggugcaguu
<SEQ ID NO. 1295;RNA;Artificial Sequence> uuuccaggaauaggcauuu
<SEQ ID NO. 1296;RNA;Artificial Sequence> ugccuaauuccuggcauga
<SEQ ID NO. 1297;RNA;Artificial Sequence> acacucuagugacuuccug
<SEQ ID NO. 1298;RNA;Artificial Sequence> ggugaggcccagccugucc
<SEQ ID NO. 1299;RNA;Artificial Sequence> cugguacagcagggucuug
<SEQ ID NO. I300;RNA;Artificial Sequence> gcuguaacucagacauucc
<SEQ ID NO. 1301;RNA;Artificial Sequence> caaggguaugggaagccau
<SEQ ID NO. 1302;RNA;Artificial Sequence> uauucacaccucacgcucu
<SEQ ID NO. 1303;RNA;Artificial Sequence> uggacaugauuuagggaag
<SEQ ID NO. I304;RNA;Artificial Sequence> gcagggacaccccccgccc
<SEQ ID NO. 1305;RNA;Artificial Sequence> ccccaccuuugggaucagc
<SEQ ID NO. 1306;RNA;Artificial Sequence> ccuccgccauuccaaguca
<SEQ ID NO. 1307;RNA;Artificial Sequence> aacacucuucuugagcaga
<SEQ ID NO. 1308;RNA;Artificial Sequence> accgugauuuggaagagag
<SEQ ID NO. 1309;RNA;Artificial Sequence> ggcaccugcuggaaaccac
<SEQ ID NO. 1310;RNA;Artificial Sequence> cacuucuugaaacagccug
<SEQ ID NO. 1311;RNA;Artificial Sequence> gggugacgguccuuuaggc
<SEQ ID NO. 1312;RNA;Artificial Sequence> cagccugccgccgucucug
<SEQ ID NO. 1313;RNA;Artificial Sequence> gucccgguucaccuugccg
<SEQ ID NO. 1314;RNA;Artificial Sequence> gagagaggcgcgucugccc
741-3608

CA 02677068 2009-09-01
<SEQ ID NO. 1315;RNA;Artificial Sequence> ccacccucaaacccugugg
<SEQ ID NO. 1316;RNA;Artificial Sequence> gggccugauggugcucacg
<SEQ ID NO. 1317;RNA;Artificial Sequence> gacucuuccugcaaaggga
<SEQ ID NO. 1318;RNA;Artificial Sequence> aacugaagaccuccacauu
<SEQ ID NO. 1319;RNA;Artificial Sequence> uaaguggcuuuuuaacaug
<SEQ ID NO. 1320;RNA;Artificial Sequence> gaaaaacacggcagcugua
<SEQ ID NO. 1321;RNA;Artificial Sequence> agcucccgagcuacucucu
<SEQ ID NO. 1322;RNA;Artificial Sequence> uugccagcauuuucacauu
<SEQ ID NO. 1323;RNA;Artificial Sequence> uuugccuuucucgugguag
<SEQ ID NO. 1324;RNA;Artificial Sequence> gaagccaguacagagaaau
<SEQ ID NO. 1325;RNA;Artificial Sequence> uucuguggugggaacauuc
<SEQ ID NO. 1326;RNA;Artificial Sequence> cgaggugucacccugcaga
<SEQ ID NO. 1327;RNA;Artificial Sequence> agcuauggugaggugugga
<SEQ ID NO. 1328;RNA;Artificial Sequence> auaaggcuuaggugccagg
<SEQ ID NO. 1329;RNA;Artificial Sequence> gcuguaagcauucugagcu
<SEQ ID NO. 1330;RNA;Artificial Sequence> ugggcuuguuguuuuuaag
<SEQ ID NO. 1331;RNA;Artificial Sequence> guccuguauauguauguag
<SEQ ID NO. 1332;RNA;Artificial Sequence> guaguuuggguguguauau
<SEQ ID NO. 1333;RNA;Artificial Sequence> uauaguagcauuucaaaau
<SEQ ID NO. 1334;RNA;Artificial Sequence> uggacguacugguuuaacc
<SEQ ID NO. 1335;RNA;Artificial Sequence> cuccuauccuuggagagca
<SEQ ID NO. 1336;RNA;Artificial Sequence> agcuggcucuccaccuugu
<SEQ ID NO. 1337;RNA;Artificial Sequence> uuacacauuauguuagaga
<SEQ ID NO. 1338;RNA;Artificial Sequence> agguagcgagcugcucugc
<SEQ ID NO. 1339;RNA;Artificial Sequence> cuauaugccuuaagccaau
<SEQ ID NO. 1340;RNA;Artificial Sequence> uauuuacucaucaggucau
<SEQ ID NO. 1341;RNA;Artificial Sequence> uuauuuuuuacaauggcca
<SEQ ID NO. 1342;RNA;Artificial Sequence> auggaauaaaccauuuuua
<SEQ ID NO. 1343;RNA;Artificial Sequence> auaaaccauuuuuacaaaa
<SEQ ID NO. 1344;RNA;Artificial Sequence> gugaugcguaguuccggcugccggu
<SEQ ID NO. 1345;RNA;Artificial Sequence> uugacaugaagaagcagcagcggcu
<SEQ ID NO. 1346;RNA;Artificial Sequence> uagggcggcgguagcugcagggguc
<SEQ ID NO. 1347;RNA;Artificial Sequence> cggggauugcagcgggccucggggc
<SEQ ID NO. 1348;RNA;Artificial Sequence> cuaagagcgcgacgcggccuagagc
<SEQ ID NO. 1349;RNA;Artificial Sequence> cggcagacggcgcagugggccgaga
<SEQ ID NO. 1350;RNA;Artificial Sequence> aaggaggcgcagcagccgcccuggc
<SEQ ID NO. 1351;RNA;Artificial Sequence> cccgucauggagauggaaaaggagu
<SEQ ID NO. 1352;RNA;Artificial Sequence> uucgagcagaucgacaaguccggga
<SEQ ID NO. 1353;RNA;Artificial Sequence> agcugggcggccauuuaccaggaua
<SEQ ID NO. 1354;RNA;Artificial Sequence> auccgacaugaagccagugacuucc
<SEQ ID NO. 1355;RNA;Artificial Sequence> ccauguagaguggccaagcuuccua
<SEQ ID NO. 1356;RNA;Artificial Sequence> aagaacaaaaaccgaaauagguaca
<SEQ ID NO. 1357;RNA;Artificial Sequence> agagacgucagucccuuugaccaua
<SEQ ID NO. 1358;RNA;Artificial Sequence> agucggauuaaacuacaucaagaag
<SEQ ID NO. I359;RNA;Artificial Sequence> gauaaugacuauaucaacgcuaguu
<SEQ ID NO. 1360;RNA;Artificial Sequence> uugauaaaaauggaagaagcccaaa
<SEQ ID NO. 1361;RNA;Artificial Sequence> aggaguuacauucuuacccagggcc
<SEQ ID NO. 1362;RNA;Artificial Sequence> ccuuugccuaacacaugcggucacu
<SEQ ID NO. 1363;RNA;Artificial Sequence> uuuugggagauggugugggagcaga
<SEQ ID NO. 1364;RNA;Artificial Sequence> aaaagcaggggugucgucaugcuca
<SEQ ID NO. 1365;RNA;Artificial Sequence> aacagagugauggagaaagguucgu
<SEQ ID NO. 1366;RNA;Artificial Sequence> uuaaaaugcgcacaauacuggccac
<SEQ ID NO. 1367;RNA;Artificial Sequence> caaaaagaagaaaaagagaugaucu
<SEQ ID NO. 1368;RNA;Artificial Sequence> uuugaagacacaaauuugaaauuaa
<SEQ ID NO. 1369;RNA;Artificial Sequence> acauugaucucugaagauaucaagu
<SEQ ID NO. 1370;RNA;Artificial Sequence> ucauauuauacagugcgacagcuag
<SEQ ID NO. 1371;RNA;Artificial Sequence> gaauuggaaaaccuuacaacccaag
<SEQ ID NO. 1372;RNA;Artificial Sequence> gaaacucgagagaucuuacauuucc
<SEQ ID NO. 1373;RNA;Artificial Sequence> cacuauaccacauggccugacuuug
<SEQ ID NO. 1374;RNA;Artificial Sequence> ggagucccugaaucaccagccucau
<SEQ ID NO. 1375;RNA;Artificial Sequence> uucuugaacuuucuuuucaaagucc
<SEQ ID NO. 1376;RNA;Artificial Sequence> cgagagucagggucacucagcccgg
<SEQ ID NO. 1377;RNA;Artificial Sequence> gagcacgggcccguuguggugcacu
<SEQ ID NO. 1378;RNA;Artificial Sequence> ugcagugcaggcaucggcaggucug
<SEQ ID NO. 1379;RNA;Artificial Sequence> ggaaccuucugucuggcugauaccu
<SEQ ID NO. 1380;RNA;Artificial Sequence> ugccucuugcugauggacaagagga
<SEQ ID NO. 1381;RNA;Artificial Sequence> aaagacccuucuuccguugauauca
<SEQ ID NO. 1382;RNA;Artificial Sequence> aagaaagugcuguuagaaaugagga
<SEQ ID NO. 1383;RNA;Artificial Sequence> aaguuucggauggggcugauccaga
<SEQ ID NO. 1384;RNA;Artificial Sequence> acagccgaccagcugcgcuucuccu
<SEQ ID NO. 1385;RNA;Artificial Sequence> uaccuggcugugaucgaaggugcca
<SEQ ID NO. I386;RNA;Artificial Sequence> aaauucaucaugggggacucuuccg
<SEQ ID NO. 1387;RNA;Artificial Sequence> gugcaggaucaguggaaggagcuuu
741-3609

CA 02677068 2009-09-01
<SEQ ID NO. 1388;RNA;Artificial Sequence> ucccacgaggaccuggagcccccac
<SEQ ID NO. 1389;RNA;Artificial Sequence> cccgagcauauccccccaccucccc
<SEQ ID NO. 1390;RNA;Artificial Sequence> cggccacccaaacgaauccuggagc
<SEQ ID NO. 1391;RNA;Artificial Sequence> ccacacaaugggaaaugcagggagu
<SEQ ID NO. 1392;RNA;Artificial Sequence> uucuucccaaaucaccaguggguga
<SEQ ID NO. 1393;RNA;Artificial Sequence> aaggaagagacccaggaggauaaag
<SEQ ID NO. 1394;RNA;Artificial Sequence> gacugccccaucaaggaagaaaaag
<SEQ ID NO. 1395;RNA;Artificial Sequence> ggaagccccuuaaaugccgcacccu
<SEQ ID NO. 1396;RNA;Artificial Sequence> uacggcaucgaaagcaugagucaag
<SEQ ID NO. 1397;RNA;Artificial Sequence> gacacugaaguuagaagucgggucg
<SEQ ID NO. 1398;RNA;Artificial Sequence> guggggggaagucuucgaggugccc
<SEQ ID NO. 1399;RNA;Artificial Sequence> caggcugccuccccagccaaagggg
<SEQ ID NO. 1400;RNA;Artificial Sequence> gagccgucacugcccgagaaggacg
<SEQ ID NO. 1401;RNA;Artificial Sequence> gaggaccaugcacugaguuacugga
<SEQ ID NO. 1402;RNA;Artificial Sequence> aagcccuuccuggucaacaugugcg
<SEQ ID NO. 1403;RNA;Artificial Sequence> guggcuacgguccucacggccggcg
<SEQ ID NO. 1404;RNA;Artificial Sequence> gcuuaccucugcuacagguuccugu
<SEQ ID NO. 1405;RNA;Artificial Sequence> uucaacagcaacacauagccugacc
<SEQ ID NO. 1406;RNA;Artificial Sequence> ccuccuccacuccaccuccacccac
<SEQ ID NO. 1407;RNA;Artificial Sequence> cuguccgccucugcccgcagagccc
<SEQ ID NO. 1408;RNA;Artificial Sequence> cacgcccgacuagcaggcaugccgc
<SEQ ID NO. 1409;RNA;Artificial Sequence> cgguagguaagggccgccggaccgc
<SEQ ID NO. 1410;RNA;Artificial Sequence> cguagagagccgggccccggacgga
<SEQ ID NO. 1411;RNA;Artificial Sequence> acguugguucugcacuaaaacccau
<SEQ ID NO. 1412;RNA;Artificial Sequence> ucuuccccggaugugugucucaccc
<SEQ ID NO. 1413;RNA;Artificial Sequence> ccucauccuuuuacuuuuugccccu
<SEQ ID NO. 1414;RNA;Artificial Sequence> uuccacuuugaguaccaaauccaca
<SEQ ID NO. 1415;RNA;Artificial Sequence> aagccauuuuuugaggagagugaaa
<SEQ ID NO. 1416;RNA;Artificial Sequence> agagaguaccaugcuggcggcgcag
<SEQ ID NO. 1417;RNA;Artificial Sequence> gagggaaggggccuacacccgucuu
<SEQ ID NO. 1418;RNA;Artificial Sequence> uggggcucgccccacccagggcucc
<SEQ ID NO. 1419;RNA;Artificial Sequence> ccuccuggagcaucccaggcgggcg
<SEQ ID NO. 1420;RNA;Artificial Sequence> ggcacgccaacagccccccccuuga
<SEQ ID NO. 1421;RNA;Artificial Sequence> aaucugcagggagcaacucuccacu
<SEQ ID NO. 1422;RNA;Artificial Sequence> uccauauuuauuuaaacaauuuuuu
<SEQ ID NO. 1423;RNA;Artificial Sequence> uccccaaaggcauccauagugcacu
<SEQ ID NO. 1424;RNA;Artificial Sequence> uagcauuuucuugaaccaauaaugu
<SEQ ID NO. 1425;RNA;Artificial Sequence> uauuaaaauuuuuugaugucagccu
<SEQ ID NO. 1426;RNA;Artificial Sequence> uugcaucaagggcuuuaucaaaaag
<SEQ ID NO. 1427;RNA;Artificial Sequence> guacaauaauaaauccucagguagu
<SEQ ID NO. 1428;RNA;Artificial Sequence> uacugggaauggaaggcuuugccau
<SEQ ID NO. 1429;RNA;Artificial Sequence> ugggccugcugcgucagaccaguac
<SEQ ID NO. 1430;RNA;Artificial Sequence> cugggaaggaggacgguuguaagca
<SEQ ID NO. 1431;RNA;Artificial Sequence> aguuguuauuuagugauauuguggg
<SEQ ID NO. 1432;RNA;Artificial Sequence> guaacgugagaagauagaacaaugc
<SEQ ID NO. 1433;RNA;Artificial Sequence> cuauaauauauaaugaacacguggg
<SEQ ID NO. 1434;RNA;Artificial Sequence> guauuuaauaagaaacaugauguga
<SEQ ID NO. 1435;RNA;Artificial Sequence> agauuacuuugucccgcuuauucuc
<SEQ ID NO. 1436;RNA;Artificial Sequence> ccucccuguuaucugcuagaucuag
<SEQ ID NO. 1437;RNA;Artificial Sequence> guucucaaucacugcucccccgugu
<SEQ ID NO. 1438;RNA;Artificial Sequence> uguauuagaaugcauguaaggucuu
<SEQ ID NO. 1439;RNA;Artiicial Sequence> ucuuguguccugaugaaaaauaugu
<SEQ ID NO. 1440;RNA;Artificial Sequence> ugcuugaaaugagaaacuuugaucu
<SEQ ID NO. 1441;RNA;Artificial Sequence> ucugcuuacuaaugugccccauguc
<SEQ ID NO. 1442;RNA;Artificial Sequence> ccaaguccaaccugccugugcauga
<SEQ ID NO. 1443;RNA;Artificial Sequence> accugaucauuacauggcugugguu
<SEQ ID NO. 1444;RNA;Artificial Sequence> uccuaagccuguugcugaagucauu
<SEQ ID NO. 1445;RNA;Artificial Sequence> ugucgcucagcaauagggugcaguu
<SEQ ID NO. 1446;RNA;Artificial Sequence> uuuccaggaauaggcauuugccuaa
<SEQ ID NO. 1447;RNA;Artificial Sequence> auuccuggcaugacacucuagugac
<SEQ ID NO. 1448;RNA;Artificial Sequence> cuuccuggugaggcccagccugucc
<SEQ ID NO. 1449;RNA;Artificial Sequence> cugguacagcagggucuugcuguaa
<SEQ ID NO. 1450;RNA;Artificial Sequence> acucagacauuccaaggguauggga
<SEQ ID NO. 1451;RNA;Artificial Sequence> aagccauauucacaccucacgcucu
<SEQ ID NO. 1452;RNA;Artificial Sequence> uggacaugauuuagggaagcaggga
<SEQ ID NO. 1453;RNA;Artificial Sequence> acaccccccgccccccaccuuuggg
<SEQ ID NO. 1454;RNA;Artificial Sequence> gaucagccuccgccauuccaaguca
<SEQ ID NO. 1455;RNA;Artificial Sequence> aacacucuucuugagcagaccguga
<SEQ ID NO. 1456;RNA;Artificial Sequence> auuuggaagagaggcaccugcugga
<SEQ ID NO. 1457;RNA;Artificial Sequence> aaaccacacuucuugaaacagccug
<SEQ ID NO. 1458;RNA;Artificial Sequence> gggugacgguccuuuaggcagccug
<SEQ ID NO. 1459;RNA;Artificial Sequence> gccgccgucucugucccgguucacc
<SEQ ID NO. 1460;RNA;Artificial Sequence> cuugccgagagaggcgcgucugccc
741-3610

CA 02677068 2009-09-01
<SEQ ID NO. 1461;RNA;Artificial Sequence> ccacccucaaacccuguggggccug
<SEQ ID NO. 1462;RNA;Artificial Sequence> gauggugcucacgacucuuccugca
<SEQ ID NO. 1463;RNA;Artificial Sequence> aaagggaacugaagaccuccacauu
<SEQ ID NO. 1464;RNA;Artificial Sequence> uaaguggcuuuuuaacaugaaaaac
<SEQ ID NO. 1465;RNA;Artificial Sequence> cacggcagcuguagcucccgagcua
<SEQ ID NO. 1466;RNA;Artificial Sequence> acucucuugccagcauuuucacauu
<SEQ ID NO. 1467;RNA;Artificial Sequence> uuugccuuucucgugguagaagcca
<SEQ ID NO. 1468;RNA;Artificial Sequence> aguacagagaaauucugugguggga
<SEQ ID NO. 1469;RNA;Artificial Sequence> aacauucgaggugucacccugcaga
<SEQ ID NO. 1470;RNA;Artificial Sequence> agcuauggugagguguggauaaggc
<SEQ ID NO. 1471;RNA;Artificial Sequence> cuuaggugccaggcuguaagcauuc
<SEQ ID NO. 1472;RNA;Artificial Sequence> cugagcugggcuuguuguuuuuaag
<SEQ ID NO. 1473;RNA;Artificial Sequence> guccuguauauguauguaguaguuu
<SEQ ID NO. 1474;RNA;Artificial Sequence> uggguguguauauauaguagcauuu
<SEQ ID NO. 1475;RNA;Artificial Sequence> ucaaaauggacguacugguuuaacc
<SEQ ID NO. 1476;RNA;Artificial Sequence> cuccuauccuuggagagcagcuggc
<SEQ ID NO. 1477;RNA;Artificial Sequence> cucuccaccuuguuacacauuaugu
<SEQ ID NO. 1478;RNA;Artificial Sequence> uuagagagguagcgagcugcucugc
<SEQ ID NO. 1479;RNA;Artificial Sequence> cuauaugccuuaagccaauauuuac
<SEQ ID NO. 1480;RNA;Artificial Sequence> cucaucaggucauuauuuuuuacaa
<SEQ ID NO. 1481;RNA;Artificial Sequence> auggccauggaauaaaccauuuuua
<SEQ ID NO. 1482;RNA;Artificial Sequence> cauggaauaaaccauuuuuacaaaa
R120 - 1986
<120> NUCLEIC ACID COMPOUNDS FOR INHIBITING
TIE GENE EXPRESSION AND USES THEREOF
<130> 07-R120PCT
<210> 1
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 1
cuacacaaau cagcgauuut t 21
<210> 2
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 2
aaaucgcuga uuuguguagt t 21
<210> 3
<211> 25
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3611

CA 02677068 2009-09-01
<400> 3
cuacacaaau cagcgauuuc caugt 25
<210> 4
<211> 27
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 4
acauggaaau cgcugauuug uguaguc 27
<210> 5
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 5
cuacacaaau cag 13
<210> 6
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 6
gauuuccaugt 11
<210> 7
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 7
ggaucuuauu ucuucggagt t 21
<210> 8
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3612

CA 02677068 2009-09-01
<400> 8
cuccgaagaa auaagaucct t 21
<210> 9
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 9
ggaucuuauu u 11
<210> 10
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNAIRNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 10
cuucggagtt 10
<210> 11
<211> 27
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 11
cauugucucc gaagaaauaa gauccuu 27
<210> 12
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 12
ggaucuua 8
<210> 13
<211> 17
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3613

CA 02677068 2009-09-01
<400> 13
uuucuucgga gacaatg 17
<210> 14
<211> 16
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 14
uucuucggag acaatg 16
<210> 15
<211> 15
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 15
ucuucggaga caatg 15
<210> 16
<211> 14
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 16
cuucggagac aatg 14
<210> 17
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 17
uucggagaca atg 13
<210> 18
<211> 12
<212> DNA
<213> Artificial Sequence
741-3614

CA 02677068 2009-09-01
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 18
ucggagacaatg 12
<210> 19
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 19
cggagacaat g 11
<210> 20
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 20
ggaucuuau 9
<210> 21
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 21
ggaucuuauu 10
<210> 22
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
741-3615

CA 02677068 2009-09-01
<400> 22
ggaucuuauu u 11
<210> 23
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 23
ggaucuuauu uc 12
<210> 24
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 24
cuacacaa 8
<210> 25
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (8)
<223> LNA-A
<400> 25
aucagcgauu utt 13
<210> 26
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-A
<400> 26
ucagcgauuutt 12
741-3616

CA 02677068 2009-09-01
<210> 27
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-A
<400> 27
cagcgauuutt 11
<210> 28
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (5)
<223> LNA-A
<400> 28
agcgauuutt 10
<210> 29
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (4) <223> LNA-A
<400> 29
gcgauuutt 9
<210> 30
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 30
cgauuutt 8
<210> 31
<211> 7
<212> DNA
<213> Artificial Sequence
741-3617

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-A
<400> 31
gauuutt 7
<210> 32
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 32
cuacacaaa 9
<210> 33
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 33
cuacacaaau 10
<210> 34
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 34
cuacacaaau c 11
<210> 35
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
741-3618

CA 02677068 2009-09-01
<222> (3)
<223> LNA-A
<400> 35
cuacacaaau ca 12
<210> 36
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 36
cuacacaaau cag 13
<210> 37
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (3) <223> LNA-A
<400> 37
cuacacaaau cagc 14
<210> 38
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<400> 38
ggaucuuauu ucu 13
<210> 39
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 39
ggaucuuauu ucuu 14
741-3619

CA 02677068 2009-09-01
<210> 40
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (8)
<223> LNA-A
<400> 40
ggaucuua 8
<210> 41
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (9)
<223> LNA-U
<400> 41
ggaucuuau 9
<210> 42
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (10)
<223> LNA-U
<400> 42
ggaucuuauu 10
<210> 43
<211> 11
<212> RNA
<213> Artificial Sequence
741-3620

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222>(11)
<223> LNA-U
<400> 43
ggaucuuauu u 11
<210> 44
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (12)
<223> LNA-C
<400> 44
ggaucuuauu uc 12
<210> 45
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (13)
<223> LNA-U
<400> 45
ggaucuuauu ucu 13
<210> 46
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
741-3621

CA 02677068 2009-09-01
<220>
<221> modified-base
<222> (14) <223> LNA-U
<400> 46
ggaucuuauu ucuu 14
<210> 47
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (8)
<223> LNA-G
<400> 47
uuucuucgga gtt 13
<210> 48
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 48
uucuucggagtt 12
<210> 49
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-G
<400> 49
ucuucggagtt 11
741-3622

CA 02677068 2009-09-01
<210> 50
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (5) <223> LNA-G
<400> 50
cuucggagtt 10
<210> 51
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (4)
<223> LNA-G
<400> 51
uucggagtt 9
<210> 52
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-G
<400> 52
ucggagtt 8
<210> 53
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
741-3623

CA 02677068 2009-09-01
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 53
cggagtt 7
<210> 54
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (8)
<223> LNA-G
<400> 54
uuucuucgga gtt 13
<210> 55
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 55
uucuucggagit 12
<210> 56
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
741-3624

CA 02677068 2009-09-01
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified-base
<222> (6)
<223> LNA-G
<400> 56
ucuucggagtt 11
<210> 57
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-C
<220>
<221> modified base
<222> (5)
<223> LNA-G
<400> 57
cuucggagtt 10
<210> 58
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (4)
<223> LNA-G
<400> 58
uucggagtt 9
<210> 59
<211> 8
<212> DNA
<213> Artificial Sequence
741-3625

CA 02677068 2009-09-01
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (3)
<223> LNA-G
<400> 59
ucggagtt 8
<210> 60
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-C
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 60
cggagtt 7
<210> 61
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (16)
<223> LNA-G
<400> 61
ggaucuuauu ucuucggagt t 21
741-3626

CA 02677068 2009-09-01
<210> 62
<211> 25
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 62
ggaucuuauu ucuucggaga caatg 25
<SEQ ID NO.63;RNA;Artificial Sequence>guauuuugaugaggaguucacggcc
<SEQ ID NO.64;RNA;Artificial Sequence>ggcccagaugaucaccaucacacca
<SEQ ID NO.65;RNA;Artificial Sequence>gggaagaaaacuauccugcggguuu
<SEQ ID NO. 66;RNA;Artificial Sequence>guuuuaauuuauuucauccaguuug
<SEQ ID NO. 67;RNA; Artificial Sequence>acguagggaaauguuaaggacuucu
<SEQ ID NO. 68;RNA; Artificial Sequence>ccaggguuuacccagugggacagag
<SEQ ID NO. 69;RNA;Artificial Sequence>agcaagguuuaaauuuguuauugug
<SEQ ID NO. 70;RNA;Artificial Sequence>uguauuauguuguucaaaugcauuu
<SEQ ID NO. 71;RNA; Artificial Sequence>uuuuaaucuuugugacaggaaagcc
<SEQ ID NO.72;RNA;Artificial Sequence>uuaaucuuugugacaggaaagcccu
<SEQ ID NO. 73;RNA;Artificial Sequence>gcugcuuaugucucccagcauggcc
<SEQ ID NO. 74;RNA;Artificial Sequence>aaguguuucagaagcuucucccuga
<SEQ ID NO. 75;RNA;Artificial Sequence>gaccaucaauaaggaagaagcccuu
<SEQ ID NO. 76;RNA; Artificial Sequence>ccaucaauaaggaagaagcccuuca
<SEQ ID NO. 77;RNA; Artificial Sequence>ucaauaaggaagaagcccuucagcg
<SEQ ID NO. 78;RNA; Artificial Sequence>aauaaggaagaagcccuucagcggc
<SEQ ID NO. 79;RNA;Artificial Sequence>aggaagaagcccuucagcggccagu
<SEQ ID NO. 80;RNA;Artificial Sequence>gcauaacuaaaggugaaaagcuccg
<SEQ ID NO. 81;RNA;Artificial Sequence>cauaacuaaaggugaaaagcuccgg
<SEQ ID NO. 82;RNA;Artificial Sequence>cuacaucacgccagucaacagucug
<SEQ ID NO. 83;RNA;Artificial Sequence> acuggauuuaagcagaguucaaaag
<SEQ ID NO. 84;RNA;Artificial Sequence>cuggauuuaagcagaguucaaaagc
<SEQ ID NO. 85;RNA;Artificial Sequence>gauuuaagcagaguucaaaagcccu
<SEQ ID NO. 86;RNA;Artificial Sequence>auuuaagcagaguucaaaagcccuu
<SEQ ID NO. 87;RNA;Artificial Sequence>uuaagcagaguucaaaagcccuuca
<SEQ ID NO. 88;RNA;Artificial Sequence>uaagcagaguucaaaagcccuucag
<SEQ ID NO. 89;RNA;Artificial Sequence>agcagaguucaaaagcccuucagcg
<SEQ ID NO.90;RNA;Artificial Sequence>cucagggucugagugaagccgcucg
<SEQ ID NO. 91;RNA;Artificial Sequence>caagcaacuacaucacgccagucaa
<SEQ ID NO. 92;RNA;Artificial Sequence> aucaauggcagcuucuuggugcgug
<SEQ ID NO. 93;RNA;Artificial Sequence>uuccagcccacauuggauucaucag
<SEQ ID NO. 94;RNA;Artificial Sequence>cagcugagaauguggaauaccuaag
<SEQ ID NO. 95;RNA;Artificial Sequence>aacguaucuccuaauuugaggcuca
<SEQ ID NO. 96;RNA;Artificial Sequence>ccuaaaauaauuucucuacaauugg
<SEQ ID NO. 97;RNA;Artificial Sequence>uggaagauucagcuaguuaggagcc
<SEQ ID NO. 98;RNA;Artificial Sequence>uuaaacucuccuagucaauauccac
<SEQ ID NO. 99;RNA;Artificial Sequence>cagccuacaguuauguucagucaca
<SEQ ID NO. 100;RNA;Artificial Sequence> guuauguucagucacacacacauac
<SEQ ID NO. 101;RNA;Artificial Sequence> cacauacaaaauguuccuuuugcuu
<SEQ ID NO. 102;RNA;Artificial Sequence> uccuuuugcuuuuaaaguaauuuuu
<SEQ ID NO. 103;RNA;Artificial Sequence> ugaccugugaagcaacagucaaugg
<SEQ ID NO. 104;RNA;Artificial Sequence> cuaucucacacaucgacaaaccaau
<SEQ ID NO. 105;RNA;Artificial Sequence> uguccucaauuguacugcuaccacu
<SEQ ID NO. 106;RNA;Artificial Sequence> aaaccguagcuggcaagcggucuua
<SEQ ID NO. 107;RNA;Artificial Sequence> uagcuggcaagcggucuuaccggcu
<SEQ ID NO. 108;RNA;Artificial Sequence> uuguaugguuaaaagauggguuacc
<SEQ ID NO. 109;RNA;Artificial Sequence> ugguuaaaagauggguuaccugcga
<SEQ ID NO. 110;RNA;Artificial Sequence> cagggaauuauacaaucuugcugag
<SEQ ID NO. 111;RNA;Artificial Sequence> acaaucuugcugagcauaaaacagu
<SEQ ID NO. 112;RNA;Artificial Sequence> ccaauaaugaagaguccuuuauccu
<SEQ ID NO. 113;RNA;Artificial Sequence> acuuuggauguuccaacgcaaguug
<SEQ ID NO. 114;RNA;Artificial Sequence> aaugcuuccacuaaacugaaaccau
<SEQ ID NO. 115;RNA;Artificial Sequence> gagaaaguuugacuuuguuaaauau
<SEQ ID NO. 116;RNA;Artificial Sequence> aaagaacuacuguauauuaaaaguu
<SEQ ID NO. 117;RNA;Artificial Sequence> uuagaaauacggguuuugacuuaac
<SEQ ID NO. 118;RNA;Artificial Sequence> aacauggguacagcaaacucagcac
<SEQ ID NO. 119;RNA;Artificial Sequence> aaagacacagaagaugcugaccuca
<SEQ ID NO. 120;RNA;Artificial Sequence> uaguagggagguuuauucagaucgc
741-3627

CA 02677068 2009-09-01
<SEQ ID NO. 121;RNA;Artificial Sequence> gccuucugcagcaggguucugggau
<SEQ ID NO. 122;RNA;Artificial Sequence> ggucugguacauauuggaaauuaug
<SEQ ID NO. 123;RNA;Artificial Sequence> cuaguccuuccgauggaagcacuag
<SEQ ID NO. 124;RNA;Artificial Sequence> ccagugaauauuguuuuuaugugga
<SEQ ID NO. 125;RNA;Artificial Sequence> augaauucaaguuggaauugguaga
<SEQ ID NO. 126;RNA;Artificial Sequence> caggacacagauuuagacuuggaga
<SEQ ID NO. 127;RNA;Artificial Sequence> cucaaagcacaguuacaguauucca
<SEQ ID NO. 128;RNA;Artificial Sequence> accacugccaccacugaugaauuaa
<SEQ ID NO. 129;RNA;Artificial Sequence> gaaacuacuagugccacaucaucac
<SEQ ID NO. 130;RNA;Artificial Sequence> aagucggacagccucaccaaacaga
<SEQ ID NO. 131;RNA;Artificial Sequence> gaaagcgaaaaauggaacaugaugg
<SEQ ID NO. 132;RNA;Artificial Sequence> cccucugauuuagcauguagacugc
<SEQ ID NO. 133;RNA;Artificial Sequence> ugagcuauuuaaggaucuauuuaug
<SEQ ID NO. 134;RNA;Artificial Sequence> aaaaggugaaaaagcacuauuauca
<SEQ ID NO. 135;RNA;Artificial Sequence> gaaaaagcacuauuaucaguucugc
<SEQ ID NO. 136;RNA;Artificial Sequence> ggcugaaaagaaagauuaaaccuac
<SEQ ID NO. 137;RNA;Artificial Sequence> uaaacccuuauaauaaaauccuucu
<SEQ ID NO. 138;RNA;Artificial Sequence> cauacuauuagccaaugcuguagac
<SEQ ID NO. 139;RNA;Artificial Sequence> gacagaagcauuuugauaggaauag
<SEQ ID NO. 140;RNA;Artificial Sequence> agagcaaauaagauaauggcccuga
<SEQ ID NO. 141;RNA;Artificial Sequence> ccaacauuuuucucuuccucaagca
<SEQ ID NO. 142;RNA;Artificial Sequence> uuaaguaugagaaaaguucagccca
<SEQ ID NO. 143;RNA;Artificial Sequence> caggaauaaagauggcugcugaacc
<SEQ ID NO. 144;RNA;Artificial Sequence> aauuugaaugaccaaguucucuuca
<SEQ ID NO. 145;RNA;Artificial Sequence> auguauaaagauagccagccuagag
<SEQ ID NO. 146;RNA;Artificial Sequence> ggcuguaacuaucucugugaagugu
<SEQ ID NO. 147;RNA;Artificial Sequence> ucugugaagugugagaaaauuucaa
<SEQ ID NO. 148;RNA;Artificial Sequence> ccuuuaaggaaaugaauccuccuga
<SEQ ID NO. 149;RNA;Artificial Sequence> aaggauacaaaaagugacaucauau
<SEQ ID NO. 150;RNA;Artificial Sequence> agaugcaauuugaaucuucaucaua
<SEQ ID NO. 151;RNA;Artificial Sequence> guucaaaacgaagacuagcuauuaa
<SEQ ID NO. 152;RNA;Artificial Sequence> gugaaaccucaucucuacuaaaaau
<SEQ ID NO. 153;RNA;Artificial Sequence> acgaaagagaagcucuaucucgccu
<SEQ ID NO. 154;RNA;Artificial Sequence> cuccacaagcgccuucgguccaguu
<SEQ ID NO. 155;RNA;Artificial Sequence> gagaagauuccaaagauguagccgc
<SEQ ID NO. 156;RNA;Artificial Sequence> aaucuggauucaaugaggagacuug
<SEQ ID NO. 157;RNA;Artificial Sequence> agaacagauuugagaguagugagga
<SEQ ID NO. 158;RNA;Artificial Sequence> ccagagcugugcagaugaguacaaa
<SEQ ID NO. 159;RNA;Artificial Sequence> ccucagauuguuguuguuaaugggc
<SEQ ID NO. 160;RNA;Artificial Sequence> cuauuuuaauuauuuuuaauuuauu
<SEQ ID NO. 161;RNA;Artificial Sequence> uuuaauuuauuaauauuuaaauaug
<SEQ ID NO. 162;RNA;Artificial Sequence> augcaguuugaauauccuuuguuuc
<SEQ ID NO. 163;RNA;Artificial Sequence> caugcugcuggcgucuaaguguuug
<SEQ ID NO. 164;RNA;Artificial Sequence> agaugugcauuucaccugugacaaa
<SEQ ID NO. 165;RNA;Artificial Sequence> ucaaaaccugugccaggcugaauua
<SEQ ID NO. 166;RNA;Artificial Sequence> gaauguggguagucauucuuacaau
<SEQ ID NO. 167;RNA;Artificial Sequence> auguggguagucauucuuacaauug
<SEQ ID NO. 168;RNA;Artificial Sequence> ugaaaaugagcaucagagaguguac
<SEQ ID NO. 169;RNA;Artificial Sequence> uugcuuuucauguagaacucagcag
<SEQ ID NO. 170;RNA;Artificial Sequence> uguauuucuauauuuauuuucagua
<SEQ ID NO. 171;RNA;Artificial Sequence> uuugauuaauguuucuuaaauggaa
<SEQ ID NO. 172;RNA;Artificial Sequence> caacguguauagugccuaaaauugu
<SEQ ID NO. 173;RNA;Artificial Sequence> cauauccuuggcuacuaacaucugg
<SEQ ID NO. I74;RNA;Artificial Sequence> uacuaacaucuggagacugugagcu
<SEQ ID NO. 175;RNA;Artificial Sequence> cauaaguugugugcuuuuuauuaau
<SEQ ID NO. 176;RNA;Artificial Sequence> gcaucauuuuggcucuucuuacauu
<SEQ ID NO. 177;RNA;Artificial Sequence> gcucuucuuacauuuguaaaaaugu
<SEQ ID NO. 178;RNA;Artificial Sequence> agauuaggucaucuuaauucauauu
<SEQ ID NO. 179;RNA;Artificial Sequence> auggaauugaaagaacuaaucauga
<SEQ ID NO. 180;RNA;Artificial Sequence> cacacucauuccuucugcucuuggg
<SEQ ID NO. 181;RNA;Artificial Sequence> uguagagguaaccaguagcuuugag
<SEQ ID NO. 182;RNA;Artificial Sequence> caaccacaugccacguaauauuuca
<SEQ ID NO. 183;RNA;Artificial Sequence> ucggaaacaaguuauucucuucacu
<SEQ ID NO. 184;RNA;Artificial Sequence> acucccaauaacuaaugcuaagaaa
<SEQ ID NO. 185;RNA;Artificial Sequence> aaugcuaagaaaugcugaaaaucaa
<SEQ ID NO. 186;RNA;Artificial Sequence> gucuuucucuaaauaugauuacuuu
<SEQ ID NO. I87;RNA;Artificial Sequence> ugaauuucaggcauuuuguucuaca
<SEQ ID NO. 188;RNA;Artificial Sequence> cgauucccucucacccgggacucuc
<SEQ ID NO. 189;RNA;Artificial Sequence> aggaaagugaaccuuuaaaguaaag
<SEQ ID NO. 190;RNA;Artificial Sequence> gaggcugcaugcucuggaagccugg
<SEQ ID NO. 191;RNA;Artificial Sequence> ucucugaacagaaaacaaaagagag
<SEQ ID NO. 192;RNA;Artificial Sequence> aacuuggcuguaaucaguuaugccg
<SEQ ID NO. 193;RNA;Artificial Sequence> agaagccaaaauuaaaagaagucca
741-3628

CA 02677068 2009-09-01
<SEQ ID NO. I94;RNA;Artificial Sequence> auuaaaagaaguccaggugagguua
<SEQ ID NO. 195;RNA;Artificial Sequence> gaauccggauuaucgggaagaggac
<SEQ ID NO. 196;RNA;Artificial Sequence> aaugugacaucaaagcaaguauugu
<SEQ ID NO. 197;RNA;Artificial Sequence> caucaaagcaaguauuguagcacuc
<SEQ ID NO. 198;RNA;Artificial Sequence> agagagagaaaacaaaaccacaaau
<SEQ ID NO. 199;RNA;Artificial Sequence> ucgcuguaguauuuaagcccauaca
<SEQ ID NO. 200;RNA;Artificial Sequence> cgcuguaguauuuaagcccauacag
<SEQ ID NO. 201;RNA;Artificial Sequence> auuuaagcccauacagaaaccuucc
<SEQ ID NO. 202;RNA;Artificial Sequence> auuaaaauaaacaugguauaccuac
<SEQ ID NO.203;RNA;Artificial Sequence> cuguucugaucggccaguuuucgga
<SEQ ID NO. 204;RNA;Artificial Sequence> aaauaauuugaacuuuggaacaggg
<SEQ ID NO.205;RNA;Artificial Sequence> ugcgaccuuaauuuaacuuuccagu
<SEQ ID NO. 206;RNA;Artificial Sequence> cugagaaagcuaaaguuugguuuug
<SEQ ID NO. 207;RNA;Artificial Sequence> aguaaagaugcuacuucccacugua
<SEQ ID NO. 208;RNA;Artificial Sequence> cugcuuaauugcugauaccauauga
<SEQ ID NO. 209;RNA;Artificial Sequence> uaccauaugaaugaaacaugggcug
<SEQ ID NO.210;RNA;Artificial Sequence> aacuuucuuauccaacuuuuucaua
<SEQ ID NO.211;RNA;Artificial Sequence> ccuugcaugacaucaugaggccgga
<SEQ ID NO. 212;RNA;Artificial Sequence> ugaauuuguauaugacugcauuugu
<SEQ ID NO. 213;RNA;Artificial Sequence> gaauccuaguagaauguuuacuacc
<SEQ ID NO. 214;RNA;Artificial Sequence> gaaagggaagaauuuuuugaugaaa
<SEQ ID NO. 215;RNA;Artificial Sequence> uaucggcaugccagugugugaauuu
<SEQ ID NO. 216;RNA;Artificial Sequence> caccucauaguagagcaauguaugu
<SEQ ID NO. 217;RNA;Artificial Sequence> ccagaauugccaaagcacauauaua
<SEQ ID NO. 218;RNA;Artificial Sequence> uggugaucuggguaauaguuucucc
<SEQ ID NO. 219;RNA;Artificial Sequence> gaucuggguaauaguuucuccaaau
<SEQ ID NO. 220;RNA;Artificial Sequence> ggaugugaugaauacuuccuagaaa
<SEQ ID NO. 221;RNA;Artificial Sequence> cauuuccacagcuacaccauauaug
<SEQ ID NO. 222;RNA;Artificial Sequence> acagcuacaccauauaugaauggag
<SEQ ID NO. 223;RNA;Artificial Sequence> ugcaguucuuacacgagaagaagau
<SEQ ID NO. 224;RNA;Artificial Sequence> acgagaagaagaucauuuacaggga
<SEQ ID NO. 225;RNA;Artificial Sequence> cgagaagaagaucauuuacagggac
<SEQ ID NO. 226;RNA;Artificial Sequence> aagaagaucauuuacagggaccuga
<SEQ ID NO. 227;RNA;Artificial Sequence> agaggaagagguguuugacugcauc
<SEQ ID NO. 228;RNA;Artificial Sequence> gaggaagagguguuugacugcaucg
<SEQ ID NO. 229;RNA;Artificial Sequence> cuacuuugagggcgaguucacaggg
<SEQ ID NO. 230;RNA;Artificial Sequence> agggcaucuccuggcaccucugucc
<SEQ ID NO. 231;RNA;Artificial Sequence> ggagugauaugguuugucuuuuuaa
<SEQ ID NO. 232;RNA;Artificial Sequence> gagugauaugguuugucuuuuuaag
<SEQ ID NO. 233;RNA;Artificial Sequence> ugcaguaaagauccuaaagguuguc
<SEQ ID NO. 234;RNA;Artificial Sequence> aguaaagauccuaaagguugucgac
<SEQ ID NO. 235;RNA;Artificial Sequence> ugacaaaggacaaccuggcaauugu
<SEQ ID NO. 236;RNA;Artificial Sequence> gcaauugugacccaguggugcgagg
<SEQ ID NO. 237;RNA;Artificial Sequence> aacaucauccauagagacaugaaau
<SEQ ID NO. 238;RNA;Artificial Sequence> ugaaauccaacaauauauuucucca
<SEQ ID NO. 239;RNA;Artificial Sequence> aacaauauauuucuccaugaaggcu
<SEQ ID NO. 240;RNA;Artificial Sequence> aacaguaaagucacgcuggaguggu
<SEQ ID NO. 241;RNA;Artificial Sequence> ugugaagaaaguaaaggaagagagg
<SEQ ID NO. 242;RNA;Artificial Sequence> cuuccgagccauccuugcaucgggc
<SEQ ID NO. 243;RNA;Artificial Sequence> aauggagguugaauauccuacugug
<SEQ ID NO. 244;RNA;Artificial Sequence> ggagguugaauauccuacuguguaa
<SEQ ID NO. 245;RNA;Artificial Sequence> auuuugaguuuucccuuguagugua
<SEQ ID NO. 246;RNA;Artificial Sequence> uauccuguuuguucuuuguugauug
<SEQ ID NO. 247;RNA;Artificial Sequence> ccuguuuguucuuuguugauugaaa
<SEQ ID NO. 248;RNA;Artificial Sequence> cucuacagccuucuuuuucuuccau
<SEQ ID NO. 249;RNA;Artificial Sequence> ucuuccauagcuaaucuuccuucua
<SEQ ID NO. 250;RNA;Artificial Sequence> auaaucuuccuguugaaugcuucau
<SEQ ID NO. 251;RNA;Artificial Sequence> uaaucuuccuguugaaugcuucaug
<SEQ ID NO. 252;RNA;Artificial Sequence> cuucaugacuugaauucuacuuuga
<SEQ ID NO.253;RNA;Artificial Sequence> aagagggagagaagcaacuacagac
<SEQ ID NO. 254;RNA;Artificial Sequence> cgucuccuaccagaccaaggucaac
<SEQ ID NO. 255;RNA;Artificial Sequence> gaucaaucggcccgacuaucucgac
<SEQ ID NO. 256;RNA;Artificial Sequence> ggacgaacauccaaccuucccaaac
<SEQ ID NO. 257;RNA;Artificial Sequence> agggucggaacccaagcuuagaacu
<SEQ ID NO. 258;RNA;Artificial Sequence> ucggaacccaagcuuagaacuuuaa
<SEQ ID NO. 259;RNA;Artificial Sequence> acccaagcuuagaacuuuaagcaac
<SEQ ID NO. 260;RNA;Artificial Sequence> gaacuuuaagcaacaagaccaccac
<SEQ ID NO. 261;RNA;Artificial Sequence> acuauucaguggcgagaaauaaagu
<SEQ ID NO. 262;RNA;Artificial Sequence> cuauucaguggcgagaaauaaaguu
<SEQ ID NO. 263;RNA; Artificial Sequence> aaacacagauaacaggaaaugaucc
<SEQ ID NO. 264;RNA;Artificial Sequence> cuuaagaaaagagaagaaaugaaac
<SEQ ID NO. 265;RNA; Artificial Sequence> cugaaggaguguguuuccauccucc
<SEQ ID NO. 266;RNA;Artificial Sequence> ucaccgcgggacugaaaaucuuuga
741-3629

CA 02677068 2009-09-01
<SEQ ID NO. 267;RNA;Artificial Sequence> agcagaaauaagcgugccguucagg
<SEQ ID NO. 268;RNA;Artificial Sequence> aagcgugccguucaggguccagaag
<SEQ ID NO. 269;RNA;Artificial Sequence> agaaacagucacucaagacugcuug
<SEQ ID NO. 270;RNA;Artificial Sequence> agaggaagaagguccaugucuuugg
<SEQ ID NO. 271;RNA;Artificial Sequence> uguauucaaaauaugccugaaacac
<SEQ ID NO. 272;RNA;Artificial Sequence> auuuuccucccuuucucuguaccuc
<SEQ ID NO.273;RNA;Artificial Sequence> caaagaaagauagagcaagacaaga
<SEQ ID NO. 274;RNA;Artificial Sequence> aagaaagauagagcaagacaagaaa
<SEQ ID NO. 275;RNA;Artificial Sequence> gaaagcauuuguuuguacaagaucc
<SEQ ID NO. 276;RNA; Artificial Sequence> ugaguuaaacgaacguacuugcaga
<SEQ ID NO. 277;RNA;Artificial Sequence> acugauacagaacgaucgauacaga
<SEQ ID NO. 27 8;RNA; Artificial Sequence> auauuauauauauauaaaaauaaau
<SEQ ID NO. 279;RNA;Artificial Sequence> auuauauauauauaaaaauaaauau
<SEQ ID NO. 280;RNA;Artificial Sequence> ucacuggauguauuugacugcugug
<SEQ ID NO. 281;RNA;Artificial Sequence> cagggaagaggaggagaugagagac
<SEQ ID NO. 282;RNA;Artificial Sequence> augaucuuuuuuuugucccacuugg
<SEQ ID NO. 283;RNA;Artificial Sequence> ggccgugaacuccucaucaaaauaccu
<SEQ ID NO. 284;RNA;Artificial Sequence> uggugugauggugaucaucugggccgu
<SEQ ID NO. 285;RNA;Artificial Sequence> aaacccgcaggauaguuuucuucccua
<SEQ ID NO. 286;RNA;Artificial Sequence> caaacuggaugaaauaaauuaaaaccc
<SEQ ID NO. 287;RNA;Artificial Sequence> agaaguccuuaacauuucccuacguga
<SEQ ID NO. 288;RNA;Artificial Sequence> cucugucccacuggguaaacccuggcc
<SEQ ID NO. 289;RNA;Artificial Sequence> cacaauaacaaauuuaaaccuugcucc
<SEQ ID NO. 290;RNA;Artificial Sequence> aaaugcauuugaacaacauaauacaca
<SEQ ID NO. 291;RNA;Artificial Sequence> ggcuuuccugucacaaagauuaaaaac
<SEQ ID NO. 292;RNA;Artificial Sequence> agggcuuuccugucacaaagauuaaaa
<SEQ ID NO. 293;RNA;Artificial Sequence> ggccaugcugggagacauaagcagcag
<SEQ ID NO.294;RNA;Artificial Sequence> ucagggagaagcuucugaaacacuucu
<SEQ ID NO. 295;RNA;Artificial Sequence> aagggcuucuuccuuauugauggucag
<SEQ ID NO. 296;RNA;Artificial Sequence> ugaagggcuucuuccuuauugaugguc
<SEQ ID NO. 297;RNA;Artificial Sequence> cgcugaagggcuucuuccuuauugaug
<SEQ ID NO. 298;RNA;Artificial Sequence> gccgcugaagggcuucuuccuuauuga
<SEQ ID NO. 299;RNA;Artificial Sequence> acuggccgcugaagggcuucuuccuua
<SEQ ID NO. 300;RNA;Artificial Sequence> cggagcuuuucaccuuuaguuaugcuu
<SEQ ID NO. 301;RNA;Artificial Sequence> ccggagcuuuucaccuuuaguuaugcu
<SEQ ID NO. 302;RNA;Artificial Sequence> cagacuguugacuggcgugauguaguu
<SEQ ID NO. 303;RNA;Artificial Sequence> cuuuugaacucugcuuaaauccagugg
<SEQ ID NO. 304;RNA;Artificial Sequence> gcuuuugaacucugcuuaaauccagug
<SEQ ID NO. 305;RNA;Artificial Sequence> agggcuuuugaacucugcuuaaaucca
<SEQ ID NO. 306;RNA;Artificial Sequence> aagggcuuuugaacucugcuuaaaucc
<SEQ ID NO. 307;RNA;Artificial Sequence> ugaagggcuuuugaacucugcuuaaau
<SEQ ID NO. 308;RNA;Artificial Sequence> cugaagggcuuuugaacucugcuuaaa
<SEQ ID NO. 309;RNA;Artificial Sequence> cgcugaagggcuuuugaacucugcuua
<SEQ ID NO.310;RNA;Artificial Sequence> cgagcggcuucacucagacccugaggc
<SEQ ID NO. 311 ;RNA;Artificial Sequence> uugacuggcgugauguaguugcuuggg
<SEQ ID NO. 312;RNA;Artificial Sequence> cacgcaccaagaagcugccauugaucc
<SEQ ID NO. 313;RNA;Artificial Sequence> cugaugaauccaaugugggcuggaauc
<SEQ ID NO. 314;RNA;Artificial Sequence> cuuagguauuccacauucucagcugug
<SEQ ID NO. 315;RNA;Artificial Sequence> ugagccucaaauuaggagauacguuuu
<SEQ ID NO. 316;RNA;Artificial Sequence> ccaauuguagagaaauuauuuuaggaa
<SEQ ID NO. 317;RNA;Artificial Sequence> ggcuccuaacuagcugaaucuuccaau
<SEQ ID NO. 318;RNA;Artificial Sequence> guggauauugacuaggagaguuuaaaa
<SEQ ID NO. 319;RNA;Artificial Sequence> ugugacugaacauaacuguaggcugaa
<SEQ ID NO. 320;RNA;Artificial Sequence> guaugugugugugacugaacauaacug
<SEQ ID NO. 321;RNA;Artificial Sequence> aagcaaaaggaacauuuuguaugugug
<SEQ ID NO. 322;RNA;Artificial Sequence> aaaaauuacuuuaaaagcaaaaggaac
<SEQ ID NO. 323;RNA;Artificial Sequence> ccauugacuguugcuucacaggucaga
<SEQ ID NO. 324;RNA;Artificial Sequence> auugguuugucgaugugugagauaguu
<SEQ ID NO. 325;RNA;Artificial Sequence> agugguagcaguacaauugaggacaag
<SEQ ID NO. 326;RNA;Artificial Sequence> uaagaccgcuugccagcuacgguuuca
<SEQ ID NO. 327;RNA;Artificial Sequence> agccgguaagaccgcuugccagcuacg
<SEQ ID NO. 328;RNA;Artificial Sequence> gguaacccaucuuuuaaccauacaacu
<SEQ ID NO. 329;RNA;Artificial Sequence> ucgcagguaacccaucuuuuaaccaua
<SEQ ID NO.330;RNA;Artificial Sequence> cucagcaagauuguauaauucccugca
<SEQ ID NO. 331;RNA;Artificial Sequence> acuguuuuaugcucagcaagauuguau
<SEQ ID NO. 332;RNA;Artificial Sequence> aggauaaaggacucuucauuauuggaa
<SEQ ID NO. 333;RNA;Artificial Sequence> caacuugcguuggaacauccaaagugu
<SEQ ID NO. 334;RNA;Artificial Sequence> augguuucaguuuaguggaagcauuua
<SEQ ID NO. 335;RNA;Artificial Sequence> auauuuaacaaagucaaacuuucucac
<SEQ ID NO. 336;RNA;Artificial Sequence> aacuuuuaauauacaguaguucuuuuc
<SEQ ID NO. 337;RNA;Artificial Sequence> guuaagucaaaacccguauuucuaaag
<SEQ ID NO. 338;RNA;Artificial Sequence> gugcugaguuugcuguacccauguuga
<SEQ ID NO. 339;RNA;Artificial Sequence> ugaggucagcaucuucugugucuuuac
741-3630

CA 02677068 2009-09-01
<SEQ ID NO. 340;RNA;Artificial Sequence> gcgaucugaauaaaccucccuacuagc
<SEQ ID NO. 341;RNA;Artificial Sequence> aucccagaacccugcugcagaaggcca
<SEQ ID NO. 342;RNA;Artificial Sequence> cauaauuuccaauauguaccagaccuu
<SEQ ID NO. 343;RNA;Artificial Sequence> cuagugcuuccaucggaaggacuaggu
<SEQ ID NO. 344;RNA;Artificial Sequence> uccacauaaaaacaauauucacuggga
<SEQ ID NO. 345;RNA;Artificial Sequence> ucuaccaauuccaacuugaauucauug
<SEQ ID NO. 346;RNA;Artificial Sequence> ucuccaagucuaaaucuguguccugag
<SEQ ID NO. 347;RNA;Artificial Sequence> uggaauacuguaacugugcuuugagga
<SEQ ID NO. 348;RNA;Artificial Sequence> uuaauucaucagugguggcagugguag
<SEQ ID NO. 349;RNA;Artificial Sequence> gugaugauguggcacuaguaguuucuu
<SEQ ID NO. 350;RNA;Artificial Sequence> ucuguuuggugaggcuguccgacuuug
<SEQ ID NO.351;RNA;Artificial Sequence> ccaucauguuccauuuuucgcuuucuc
<SEQ ID NO. 352;RNA;Artificial Sequence> gcagucuacaugcuaaaucagagggua
<SEQ ID NO. 353;RNA;Artificial Sequence> cauaaauagauccuuaaauagcucaaa
<SEQ ID NO.354;RNA;Artificial Sequence> ugauaauagugcuuuuucaccuuuuuc
<SEQ ID NO. 355;RNA;Artificial Sequence> gcagaacugauaauagugcuuuuucac
<SEQ ID NO. 356;RNA;Artificial Sequence> guagguuuaaucuuucuuuucagccau
<SEQ ID NO. 357;RNA;Artificial Sequence> agaaggauuuuauuauaaggguuuaau
<SEQ ID NO. 358;RNA;Artificial Sequence> gucuacagcauuggcuaauaguaugaa
<SEQ ID NO. 359;RNA;Artificial Sequence> cuauuccuaucaaaaugcuucugucua
<SEQ ID NO. 360;RNA;Artificial Sequence> ucagggccauuaucuuauuugcucuau
<SEQ ID NO. 361;RNA;Artificial Sequence> ugcuugaggaagagaaaaauguugguc
<SEQ ID NO. 362;RNA;Artificial Sequence> ugggcugaacuuuucucauacuuaaag
<SEQ ID NO. 363;RNA;Artificial Sequence> gguucagcagccaucuuuauuccugcg
<SEQ ID NO. 364;RNA;Artificial Sequence> ugaagagaacuuggucauucaaauuuc
<SEQ ID NO. 365;RNA;Artificial Sequence> cucuaggcuggcuaucuuuauacauac
<SEQ ID NO. 366;RNA;Artificial Sequence> acacuucacagagauaguuacagccau
<SEQ ID NO. 367;RNA;Artificial Sequence> uugaaauuuucucacacuucacagaga
<SEQ ID NO. 368;RNA;Artificial Sequence> ucaggaggauucauuuccuuaaaggaa
<SEQ ID NO. 369;RNA;Artificial Sequence> auaugaugucacuuuuuguauccuuga
<SEQ ID NO. 370;RNA;Artificial Sequence> uaugaugaagauucaaauugcaucuua
<SEQ ID NO. 371;RNA;Artificial Sequence> uuaauagcuagucuucguuuugaacag
<SEQ ID NO. 372;RNA;Artificial Sequence> auuuuuaguagagaugagguuucacca
<SEQ ID NO. 373;RNA;Artificial Sequence> aggcgagauagagcuucucuuucguuc
<SEQ ID NO. 374;RNA;Artificial Sequence> aacuggaccgaaggcgcuuguggagaa
<SEQ ID NO. 375;RNA;Artificial Sequence> gcggcuacaucuuuggaaucuucuccu
<SEQ ID NO. 376;RNA;Artificial Sequence> caagucuccucauugaauccagauugg
<SEQ ID NO. 377;RNA;Artificial Sequence> uccucacuacucucaaaucuguucugg
<SEQ ID NO. 378;RNA;Artificial Sequence> uuuguacucaucugcacagcucuggcu
<SEQ ID NO.379;RNA;Artificial Sequence> gcccauuaacaacaacaaucugaggug
<SEQ ID NO. 380;RNA;Artificial Sequence> aauaaauuaaaaauaauuaaaauagug
<SEQ ID NO. 381;RNA;Artificial Sequence> cauauuuaaauauuaauaaauuaaaaa
<SEQ ID NO. 382;RNA;Artificial Sequence> gaaacaaaggauauucaaacugcauag
<SEQ ID NO. 383;RNA;Artificial Sequence> caaacacuuagacgccagcagcauggg
<SEQ ID NO. 384;RNA;Artificial Sequence> uuugucacaggugaaaugcacaucuga
<SEQ ID NO. 385;RNA;Artificial Sequence> uaauucagccuggcacagguuuugauc
<SEQ ID NO. 386;RNA;Artificial Sequence> auuguaagaaugacuacccacauucac
<SEQ ID NO. 387;RNA;Artificial Sequence> caauuguaagaaugacuacccacauuc
<SEQ ID NO. 388;RNA;Artificial Sequence> guacacucucugaugcucauuuucaua
<SEQ ID NO. 389;RNA;Artificial Sequence> cugcugaguucuacaugaaaagcaaau
<SEQ ID NO. 390;RNA;Artificial Sequence> uacugaaaauaaauauagaaauacaac
<SEQ ID NO. 391;RNA;Artificial Sequence> uuccauuuaagaaacauuaaucaaaac
<SEQ ID NO. 392;RNA;Artificial Sequence> acaauuuuaggcacuauacacguuguu
<SEQ ID NO. 393;RNA;Artificial Sequence> ccagauguuaguagccaaggauauggu
<SEQ ID NO. 394;RNA;Artificial Sequence> agcucacagucuccagauguuaguagc
<SEQ ID NO. 395;RNA;Artificial Sequence> auuaauaaaaagcacacaacuuauggc
<SEQ ID NO. 396;RNA;Artificial Sequence> aauguaagaagagccaaaaugaugcau
<SEQ ID NO. 397;RNA;Artificial Sequence> acauuuuuacaaauguaagaagagcca
<SEQ ID NO. 398;RNA;Artificial Sequence> aauaugaauuaagaugaccuaaucugu
<SEQ ID NO. 399;RNA;Artificial Sequence> ucaugauuaguucuuucaauuccaucc
<SEQ ID NO. 400;RNA;Artificial Sequence> cccaagagcagaaggaaugagugugca
<SEQ ID NO. 401;RNA;Artificial Sequence> cucaaagcuacugguuaccucuacacc
<SEQ ID NO. 402;RNA;Artificial Sequence> ugaaauauuacguggcaugugguuggg
<SEQ ID NO. 403;RNA;Artificial Sequence> agugaagagaauaacuuguuuccgaag
<SEQ ID NO. 404;RNA;Artificial Sequence> uuucuuagcauuaguuauugggaguga
<SEQ ID NO. 405;RNA;Artificial Sequence> uugauuuucagcauuucuuagcauuag
<SEQ ID NO. 406;RNA;Artificial Sequence> aaaguaaucauauuuagagaaagacag
<SEQ ID NO. 407;RNA;Artificial Sequence> uguagaacaaaaugccugaaauucagc
<SEQ ID NO. 408;RNA;Artificial Sequence> gagagucccgggugagagggaaucgcc
<SEQ ID NO. 409;RNA;Artificial Sequence> cuuuacuuuaaagguucacuuuccuug
<SEQ ID NO. 410;RNA;Artificial Sequence> ccaggcuuccagagcaugcagccuccu
<SEQ ID NO. 41 l;RNA;Artificial Sequence> cucucuuuuguuuucuguucagagaaa
<SEQ ID NO. 412;RNA;Artificial Sequence> cggcauaacugauuacagccaaguuca
741-3631

CA 02677068 2009-09-01
<SEQ ID NO. 413;RNA;Artificial Sequence> uggacuucuuuuaauuuuggcuucuuc
<SEQ ID NO. 414;RNA;Artificial Sequence> uaaccucaccuggacuucuuuuaauuu
<SEQ ID NO.415;RNA;Artifcial Sequence> guccucuucccgauaauccggauucag
<SEQ ID NO. 416;RNA;Artificial Sequence> acaauacuugcuuugaugucacauuaa
<SEQ ID NO. 417;RNA;Artificial Sequence> gagugcuacaauacuugcuuugauguc
<SEQ ID NO. 418;RNA;Artificial Sequence> auuugugguuuuguuuucucucucucu
<SEQ ID NO.419;RNA;Artificial Sequence> uguaugggcuuaaauacuacagcgagg
<SEQ ID NO.420;RNA;Artificial Sequence> cuguaugggcuuaaauacuacagcgag
<SEQ ID NO. 421;RNA;Artificial Sequence> ggaagguuucuguaugggcuuaaauac
<SEQ ID NO. 422;RNA;Artificial Sequence> guagguauaccauguuuauuuuaauac
<SEQ ID NO.423;RNA;Artiicial Sequence> uccgaaaacuggccgaucagaacagcc
<SEQ ID NO. 424;RNA;Artificial Sequence> cccuguuccaaaguucaaauuauuugu
<SEQ ID NO. 425;RNA;Artificial Sequence> acuggaaaguuaaauuaaggucgcaau
<SEQ ID NO.426;RNA;Artiicial Sequence> caaaaccaaacuuuagcuuucucagcc
<SEQ ID NO. 427;RNA;Artificial Sequence> uacagugggaaguagcaucuuuacuuu
<SEQ ID NO.428;RNA;Artiicial Sequence> ucauaugguaucagcaauuaagcagua
<SEQ ID NO. 429;RNA;Artificial Sequence> cagcccauguuucauucauaugguauc
<SEQ ID NO. 430;RNA;Artificial Sequence> uaugaaaaaguuggauaagaaaguugg
<SEQ ID NO.431;RNA;Artificial Sequence> uccggccucaugaugucaugcaaggcu
<SEQ ID NO. 432;RNA;Artificial Sequence> acaaaugcagucauauacaaauucagg
<SEQ ID NO. 433;RNA;Artificial Sequence> gguaguaaacauucuacuaggauucuu
<SEQ ID NO. 434;RNA; Artificial Sequence> uuucaucaaaaaauucuucccuuucug
<SEQ ID NO. 435;RNA;Artificial Sequence> aaauucacacacuggcaugccgauagc
<SEQ ID NO. 436;RNA;Artificial Sequence> acauacauugcucuacuaugaggugaa
<SEQ ID NO. 437;RNA;Artificial Sequence> uauauaugugcuuuggcaauucuggug
<SEQ ID NO. 438;RNA;Artificial Sequence> ggagaaacuauuacccagaucaccacu
<SEQ ID NO. 439;RNA;Artificial Sequence> auuuggagaaacuauuacccagaucac
<SEQ ID NO. 440;RNA;Artificial Sequence> uuucuaggaaguauucaucacauccac
<SEQ ID NO. 441;RNA;Artificial Sequence> cauauaugguguagcuguggaaaugcg
<SEQ ID NO. 442;RNA;Artificial Sequence> cuccauucauauaugguguagcugugg
<SEQ ID NO. 443;RNA;Artificial Sequence> aucuucuucucguguaagaacugcagc
<SEQ ID NO. 444;RNA;Artificial Sequence> ucccuguaaaugaucuucuucucgugu
<SEQ ID NO. 445;RNA;Artificial Sequence> gucccuguaaaugaucuucuucucgug
<SEQ ID NO. 446;RNA;Artificial Sequence> ucaggucccuguaaaugaucuucuucu
<SEQ ID NO. 447;RNA;Artificial Sequence> gaugcagucaaacaccucuuccucugu
<SEQ ID NO. 448;RNA;Artificial Sequence> cgaugcagucaaacaccucuuccucug
<SEQ ID NO. 449;RNA;Artificial Sequence> cccugugaacucgcccucaaaguagcg
<SEQ ID NO. 450;RNA;Artificial Sequence> ggacagaggugccaggagaugcccuca
<SEQ ID NO.451;RNA;Artificial Sequence> uuaaaaagacaaaccauaucacuccuu
<SEQ ID NO. 452;RNA;Artificial Sequence> cuuaaaaagacaaaccauaucacuccu
<SEQ ID NO.453;RNA;Artiicial Sequence> gacaaccuuuaggaucuuuacugcaac
<SEQ ID NO. 454;RNA;Artificial Sequence> gucgacaaccuuuaggaucuuuacugc
<SEQ ID NO. 455;RNA;Artificial Sequence> acaauugccagguuguccuuugucaug
<SEQ ID NO. 456;RNA;Artificial Sequence> ccucgcaccacugggucacaauugcca
<SEQ ID NO. 457;RNA;Artificial Sequence> auuucaugucucuauggaugauguucu
<SEQ ID NO. 458;RNA;Artificial Sequence> uggagaaauauauuguuggauuucaug
<SEQ ID NO. 459;RNA;Artificial Sequence> agccuucauggagaaauauauuguugg
<SEQ ID NO. 460;RNA;Artificial Sequence> accacuccagcgugacuuuacuguugc
<SEQ ID NO. 461;RNA;Artificial Sequence> ccucucuuccuuuacuuucuucacaca
<SEQ ID NO.462;RNA;Artificial Sequence> gcccgaugcaaggauggcucggaagcg
<SEQ ID NO. 463;RNA;Artificial Sequence> cacaguaggauauucaaccuccauuuc
<SEQ ID NO. 464;RNA;Artificial Sequence> uuacacaguaggauauucaaccuccau
<SEQ ID NO.465;RNA;Artificial Sequence> uacacuacaagggaaaacucaaaaucu
<SEQ ID NO. 466;RNA;Artificial Sequence> caaucaacaaagaacaaacaggauaaa
<SEQ ID NO. 467;RNA;Artificial Sequence> uuucaaucaacaaagaacaaacaggau
<SEQ ID NO. 468;RNA;Artificial Sequence> auggaagaaaaagaaggcuguagagaa
<SEQ ID NO. 469;RNA;Artificial Sequence> uagaaggaagauuagcuauggaagaaa
<SEQ ID NO. 470;RNA;Artificial Sequence> augaagcauucaacaggaagauuauuu
<SEQ ID NO. 471;RNA;Artificial Sequence> caugaagcauucaacaggaagauuauu
<SEQ ID NO.472;RNA;Artificial Sequence> ucaaaguagaauucaagucaugaagca
<SEQ ID NO. 473;RNA;Artificial Sequence> gucuguaguugcuucucucccucuuag
<SEQ ID NO. 474;RNA;Artificial Sequence> guugaccuuggucugguaggagacggc
<SEQ ID NO. 475;RNA;Artificial Sequence> gucgagauagucgggccgauugaucuc
<SEQ ID NO. 476;RNA;Artificial Sequence> guuugggaagguuggauguucguccuc
<SEQ ID NO. 477;RNA;Artificial Sequence> aguucuaagcuuggguuccgacccuaa
<SEQ ID NO. 478;RNA;Artificial Sequence> uuaaaguucuaagcuuggguuccgacc
<SEQ ID NO. 479;RNA;Artificial Sequence> guugcuuaaaguucuaagcuuggguuc
<SEQ ID NO. 480;RNA;Artificial Sequence> gugguggucuuguugcuuaaaguucua
<SEQ ID NO.481;RNA;Artificial Sequence> acuuuauuucucgccacugaauaguag
<SEQ ID NO. 482;RNA;Artificial Sequence> aacuuuauuucucgccacugaauagua
<SEQ ID NO. 483;RNA;Artificial Sequence> ggaucauuuccuguuaucuguguuugu
<SEQ ID NO. 484;RNA;Artificial Sequence> guuucauuucuucucuuuucuuaaggc
<SEQ ID NO. 485;RNA;Artificial Sequence> ggaggauggaaacacacuccuucaguu
741-3632

CA 02677068 2009-09-01
<SEQ ID NO. 486;RNA;Artificial Sequence> ucaaagauuuucagucccgcggugaca
<SEQ ID NO. 487;RNA;Artificial Sequence> ccugaacggcacgcuuauuucugcugu
<SEQ ID NO. 488;RNA;Artificial Sequence> cuucuggacccugaacggcacgcuuau
<SEQ ID NO. 489;RNA;Artificial Sequence> caagcagucuugagugacuguuucuuc
<SEQ ID NO. 490;RNA;Artificial Sequence> ccaaagacauggaccuucuuccucuga
<SEQ ID NO. 491;RNA;Artificial Sequence> guguuucaggcauauuuugaauacauc
<SEQ ID NO. 492;RNA;Artificial Sequence> gagguacagagaaagggaggaaaauag
<SEQ ID NO. 493;RNA;Artificial Sequence> ucuugucuugcucuaucuuucuuuggu
<SEQ ID NO. 494;RNA;Artificial Sequence> uuucuugucuugcucuaucuuucuuug
<SEQ ID NO. 495;RNA;Artificial Sequence> ggaucuuguacaaacaaaugcuuucuc
<SEQ ID NO. 496;RNA;Artificial Sequence> ucugcaaguacguucguuuaacucaag
<SEQ ID NO. 497;RNA;Artificial Sequence> ucuguaucgaucguucuguaucagucu
<SEQ ID NO. 498;RNA;Artificial Sequence> auuuauuuuuauauauauauaauauau
<SEQ ID NO. 499;RNA;Artificial Sequence> auauuuauuuuuauauauauauaauau
<SEQ ID NO.500;RNA;Artificial Sequence> cacagcagucaaauacauccagugaag
<SEQ ID NO. 501;RNA;Artificial Sequence> gucucucaucuccuccucuucccuguc
<SEQ ID NO. 502;RNA;Artificial Sequence> ccaagugggacaaaaaaaagaucaugc
<SEQ ID NO.503;RNA;Artificial Sequence> guauuuugaugagg
<SEQ ID NO. 504;RNA;Artificial Sequence> ggcccagaugau
<SEQ ID NO. 505;RNA;Artificial Sequence> gggaagaaaacuau
<SEQ ID NO. 506;RNA;Artificial Sequence> guuuuaauuuauuuc
<SEQ ID NO. 507;RNA;Artificial Sequence> acguagggaaau
<SEQ ID NO. 508;RNA;Artificial Sequence> ccaggguuuacc
<SEQ ID NO. 509;RNA;Artificial Sequence> agcaagguuua
<SEQ ID NO. 510;RNA;Artificial Sequence> uguauuauguug
<SEQ ID NO.511;RNA;Artificial Sequence> uuuuaaucuuuguga
<SEQ ID NO. 512;RNA;Artificial Sequence> uuaaucuuugugac
<SEQ ID NO. 513;RNA;Artificial Sequence> gcugcuuaugucu
<SEQ ID NO. 514;RNA;Artificial Sequence> aaguguuucagaag
<SEQ ID NO. 515;RNA;Artificial Sequence> gaccaucaauaag
<SEQ ID NO. 516;RNA;Artificial Sequence> ccaucaauaagga
<SEQ ID NO. 517;RNA;Artificial Sequence> ucaauaaggaagaa
<SEQ ID NO. 518;RNA;Artificial Sequence> aauaaggaagaagc
<SEQ ID NO. 519;RNA;Artificial Sequence> aggaagaagcccu
<SEQ ID NO. 520;RNA;Artificial Sequence> gcauaacuaaagg
<SEQ ID NO.521;RNA;Artificial Sequence> cauaacuaaaggug
<SEQ ID NO. 522;RNA;Artificial Sequence> cuacaucacgcc
<SEQ ID NO. 523;RNA;Artificial Sequence> acuggauuuaag
<SEQ ID NO. 524;RNA;Artificial Sequence> cuggauuuaagc
<SEQ ID NO. 525;RNA;Artificial Sequence> gauuuaagcagag
<SEQ ID NO. 526;RNA;Artificial Sequence> auuuaagcagagu
<SEQ ID NO. 527;RNA;Artificial Sequence> uuaagcagaguuc
<SEQ ID NO. 528;RNA;Artificial Sequence> uaagcagaguuca
<SEQ ID NO. 529;RNA;Artificial Sequence> agcagaguucaaaa
<SEQ ID NO. 530;RNA;Artificial Sequence> cucagggucuga
<SEQ ID NO. 531;RNA;Artificial Sequence> caagcaacuacau
<SEQ ID NO. 532;RNA;Artificial Sequence> aucaauggcagc
<SEQ ID NO. 533;RNA;Artificial Sequence> uuccagcccac
<SEQ ID NO. 534;RNA;Artificial Sequence> cagcugagaaug
<SEQ ID NO. 535;RNA;Artificial Sequence> aacguaucuccua
<SEQ ID NO. 536;RNA;Artificial Sequence> ccuaaaauaauuuc
<SEQ ID NO. 537;RNA;Artificial Sequence> uggaagauucagc
<SEQ ID NO. 538;RNA;Artificial Sequence> uuaaacucuccu
<SEQ ID NO. 539;RNA;Artificial Sequence> cagccuacaguu
<SEQ ID NO. 540;RNA;Artificial Sequence> guuauguucaguc
<SEQ ID NO. 541;RNA;Artificial Sequence> cacauacaaaaug
<SEQ ID NO. 542;RNA;Artificial Sequence> uccuuuugc
<SEQ ID NO. 543;RNA;Artificial Sequence> ugaccugugaag
<SEQ ID NO. 544;RNA;Artificial Sequence> cuaucucacaca
<SEQ ID NO. 545;RNA;Artificial Sequence> uguccucaauugu
<SEQ ID NO. 546;RNA;Artificial Sequence> aaaccguagcug
<SEQ ID NO. 547;RNA;Artificial Sequence> uagcuggcaagc
<SEQ ID NO. 548;RNA;Artificial Sequence> uuguaugguuaaaa
<SEQ ID NO. 549;RNA;Artificial Sequence> ugguuaaaagaugg
<SEQ ID NO. 550;RNA;Artificial Sequence> cagggaauuauac
<SEQ ID NO. 551;RNA;Artificial Sequence> acaaucuugcug
<SEQ ID NO. 552;RNA;Artificial Sequence> ccaauaaugaaga
<SEQ ID NO. 553;RNA;Artificial Sequence> acuuuggauguuc
<SEQ ID NO. 554;RNA;Artificial Sequence> aaugcuuccacu
<SEQ ID NO.555;RNA;Artificial Sequence> gagaaaguuug
<SEQ ID NO.556;RNA;Artificial Sequence> aaagaacuacu
<SEQ ID NO. 557;RNA;Artificial Sequence> uuagaaauacgg
<SEQ ID NO. 558;RNA;Artificial Sequence> aacauggguaca
741-3633

CA 02677068 2009-09-01
<SEQ ID NO. 559;RNA;Artificial Sequence> aaagacacagaaga
<SEQ ID NO. 560;RNA;Artificial Sequence> uaguagggagg
<SEQ ID NO. 561;RNA;Artificial Sequence> gccuucugcagc
<SEQ ID NO. 562;RNA;Artificial Sequence> ggucugguac
<SEQ ID NO. 563;RNA;Artificial Sequence> cuaguccuuccg
<SEQ ID NO. 564;RNA;Artificial Sequence> ccagugaauauu
<SEQ ID NO. 565;RNA;Artificial Sequence> augaauucaaguu
<SEQ ID NO. 566;RNA;Artificial Sequence> caggacacagau
<SEQ ID NO. 567;RNA;Artificial Sequence> cucaaagcacag
<SEQ ID NO. 568;RNA;Artificial Sequence> accacugcca
<SEQ ID NO. 569;RNA;Artificial Sequence> gaaacuacuagug
<SEQ ID NO. 570;RNA;Artificial Sequence> aagucggacagc
<SEQ ID NO. 571;RNA;Artificial Sequence> gaaagcgaaaaau
<SEQ ID NO. 572;RNA;Artificial Sequence> cccucugauuuag
<SEQ ID NO. 573;RNA;Artificial Sequence> ugagcuauuuaa
<SEQ ID NO. 574;RNA;Artificial Sequence> aaaaggugaaaaa
<SEQ ID NO. 575;RNA;Artificial Sequence> gaaaaagcacuauu
<SEQ ID NO. 576;RNA;Artificial Sequence> ggcugaaaagaa
<SEQ ID NO. 577;RNA;Artificial Sequence> uaaacccuuaua
<SEQ ID NO. 578;RNA;Artificial Sequence> cauacuauuagcc
<SEQ ID NO. 579;RNA;Artificial Sequence> gacagaagcauu
<SEQ ID NO. 580;RNA;Artificial Sequence> agagcaaauaagau
<SEQ ID NO. 581;RNA;Artificial Sequence> ccaacauuuuucuc
<SEQ ID NO. 582;RNA;Artificial Sequence> uuaaguaugagaaaa
<SEQ ID NO. 583;RNA;Artificial Sequence> caggaauaaagaug
<SEQ ID NO. 584;RNA;Artificial Sequence> aauuugaaugacc
<SEQ ID NO. 585;RNA;Artificial Sequence> auguauaaagauag
<SEQ ID NO. 586;RNA;Artificial Sequence> ggcuguaacuau
<SEQ ID NO. 587;RNA;Artificial Sequence> ucugugaagug
<SEQ ID NO. 588;RNA;Artificial Sequence> ccuuuaaggaaaug
<SEQ ID NO. 589;RNA;Artificial Sequence> aaggauacaaaaa
<SEQ ID NO. 590;RNA;Artificial Sequence> agaugcaauuug
<SEQ ID NO. 591;RNA;Artificial Sequence> guucaaaacgaa
<SEQ ID NO. 592;RNA;Artificial Sequence> gugaaaccuca
<SEQ ID NO. 593;RNA;Artificial Sequence> acgaaagagaagc
<SEQ ID NO. 594;RNA;Artificial Sequence> cuccacaagcgc
<SEQ ID NO. 595;RNA; Artificial Sequence> gagaagauuccaaa
<SEQ ID NO. 596;RNA;Artificial Sequence> aaucuggauucaa
<SEQ ID NO. 597;RNA;Artificial Sequence> agaacagauuuga
<SEQ ID NO. 598;RNA;Artificial Sequence> ccagagcugug
<SEQ ID NO. 599;RNA;Artificial Sequence> ccucagauuguu
<SEQ ID NO. 600;RNA;Artificial Sequence> cuauuuuaauua
<SEQ ID NO. 601;RNA;Artificial Sequence> uuuaauuuauuaa
<SEQ ID NO.602;RNA;Artificial Sequence> augcaguuugaa
<SEQ ID NO. 603;RNA;Artificial Sequence> caugcugcugg
<SEQ ID NO. 604;RNA;Artificial Sequence> agaugugcauuuc
<SEQ ID NO. 605;RNA;Artificial Sequence> ucaaaaccugug
<SEQ ID NO. 606;RNA;Artificial Sequence> gaaugugggua
<SEQ ID NO. 607;RNA;Artificial Sequence> auguggguag
<SEQ ID NO. 608;RNA;Artificial Sequence> ugaaaaugagcau
<SEQ ID NO. 609;RNA;Artificial Sequence> uugcuuuucaugu
<SEQ ID NO. 610;RNA;Artificial Sequence> uguauuucuaua
<SEQ ID NO. 611;RNA;Artificial Sequence> uuugauuaauguu
<SEQ ID NO. 612;RNA;Artificial Sequence> caacguguauag
<SEQ ID NO.613;RNA;Artificial Sequence> cauauccuuggc
<SEQ ID NO. 614;RNA;Artificial Sequence> uacuaacaucugg
<SEQ ID NO. 615;RNA;Artificial Sequence> cauaaguugug
<SEQ ID NO. 616;RNA;Artificial Sequence> gcaucauuuugg
<SEQ ID NO. 617;RNA;Artificial Sequence> gcucuucuua
<SEQ ID NO. 618;RNA;Artificial Sequence> agauuagguc
<SEQ ID NO. 619;RNA;Artificial Sequence> auggaauugaaa
<SEQ ID NO. 620;RNA;Artificial Sequence> cacacucauuccu
<SEQ ID NO. 621;RNA;Artificial Sequence> uguagagguaac
<SEQ ID NO. 622;RNA;Artificial Sequence> caaccacaugc
<SEQ ID NO. 623;RNA;Artificial Sequence> ucggaaacaagu
<SEQ ID NO. 624;RNA; Artificial Sequence> acucccaauaa
<SEQ ID NO. 625;RNA;Artificial Sequence> aaugcuaagaaau
<SEQ ID NO.626;RNA;Artificial Sequence> gucuuucucua
<SEQ ID NO. 627;RNA;Artificial Sequence> ugaauuucagg
<SEQ ID NO. 628;RNA;Artificial Sequence> cgauucccucuca
<SEQ ID NO. 629;RNA;Artificial Sequence> aggaaagugaa
<SEQ ID NO. 630;RNA;Artificial Sequence> gaggcugcaugc
<SEQ ID NO. 631;RNA;Artificial Sequence> ucucugaacag
741-3634

CA 02677068 2009-09-01
<SEQ ID NO. 632;RNA;Artificial Sequence> aacuuggcugua
<SEQ ID NO. 633;RNA;Artificial Sequence> agaagccaaaau
<SEQ ID NO. 634;RNA;Artificial Sequence> auuaaaagaagucc
<SEQ ID NO. 635;RNA;Artificial Sequence> gaauccggauuauc
<SEQ ID NO. 636;RNA;Artificial Sequence> aaugugacauca
<SEQ ID NO. 637;RNA;Artificial Sequence> caucaaagcaagu
<SEQ ID NO. 638;RNA;Artificial Sequence> agagagagaaa
<SEQ ID NO. 639;RNA;Artificial Sequence> ucgcuguaguauu
<SEQ ID NO. 640;RNA;Artificial Sequence> cgcuguaguauuua
<SEQ ID NO. 641;RNA;Artificial Sequence> auuuaagcccaua
<SEQ ID NO. 642;RNA;Artificial Sequence> auuaaaauaaacaug
<SEQ ID NO. 643;RNA;Artificial Sequence> cuguucugaucg
<SEQ ID NO. 644;RNA;Artificial Sequence> aaauaauuugaacuuu
<SEQ ID NO. 645;RNA;Artificial Sequence> ugcgaccuuaau
<SEQ ID NO. 646;RNA;Artificial Sequence> cugagaaagcu
<SEQ ID NO. 647;RNA;Artificial Sequence> aguaaagaugcua
<SEQ ID NO. 648;RNA;Artificial Sequence> cugcuuaauugc
<SEQ ID NO. 649;RNA;Artificial Sequence> uaccauaugaauga
<SEQ ID NO. 650;RNA;Artificial Sequence> aacuuucuuauc
<SEQ ID NO. 651;RNA;Artificial Sequence> ccuugcaugacau
<SEQ ID NO. 652;RNA;Artificial Sequence> ugaauuuguauaug
<SEQ ID NO. 653;RNA;Artificial Sequence> gaauccuaguag
<SEQ ID NO. 654;RNA;Artificial Sequence> gaaagggaag
<SEQ ID NO. 655;RNA;Artificial Sequence> uaucggcaugc
<SEQ ID NO. 656;RNA;Artificial Sequence> caccucauagua
<SEQ ID NO. 657;RNA;Artificial Sequence> ccagaauugcc
<SEQ ID NO. 65 8;RNA; Artificial Sequence> uggugaucugg
<SEQ ID NO. 659;RNA;Artificial Sequence> gaucuggguaau
<SEQ ID NO. 660;RNA;Artificial Sequence> ggaugugaugaa
<SEQ ID NO. 661;RNA;Artificial Sequence> cauuuccacagc
<SEQ ID NO. 662;RNA;Artificial Sequence> acagcuacacc
<SEQ ID NO. 663;RNA;Artificial Sequence> ugcaguucuuac
<SEQ ID NO. 664;RNA;Artificial Sequence> acgagaagaaga
<SEQ ID NO. 665;RNA;Artificial Sequence> cgagaagaagau
<SEQ ID NO. 666;RNA;Artificial Sequence> aagaagaucauuuac
<SEQ ID NO. 667;RNA;Artificial Sequence> agaggaagagg
<SEQ ID NO. 668;RNA;Artificial Sequence> gaggaagaggug
<SEQ ID NO. 669;RNA;Artificial Sequence> cuacuuugagggc
<SEQ ID NO. 670;RNA;Artificial Sequence> agggcaucuccu
<SEQ ID NO. 671;RNA;Artificial Sequence> ggagugauau
<SEQ ID NO. 672;RNA;Artificial Sequence> gagugauaugg
<SEQ ID NO. 673;RNA;Artificial Sequence> ugcaguaaagau
<SEQ ID NO. 674;RNA;Artificial Sequence> aguaaagauccua
<SEQ ID NO. 675;RNA;Artificial Sequence> ugacaaaggaca
<SEQ ID NO. 676;RNA;Artificial Sequence> gcaauugugaccc
<SEQ ID NO. 677;RNA;Artificial Sequence> aacaucauccau
<SEQ ID NO. 678;RNA;Artificial Sequence> ugaaauccaaca
<SEQ ID NO. 679;RNA;Artificial Sequence> aacaauauauuucuc
<SEQ ID NO. 680;RNA;Artificial Sequence> aacaguaaagucac
<SEQ ID NO. 681;RNA;Artificial Sequence> ugugaagaaaguaa
<SEQ ID NO. 682;RNA;Artificial Sequence> cuuccgagccauc
<SEQ ID NO. 683;RNA;Artificial Sequence> aauggagguuga
<SEQ ID NO. 684;RNA;Artificial Sequence> ggagguugaaua
<SEQ ID NO. 685;RNA;Artificial Sequence> auuuugaguuuuc
<SEQ ID NO. 686;RNA;Artificial Sequence> uauccuguuugu
<SEQ ID NO. 687;RNA;Artificial Sequence> ccuguuuguuc
<SEQ ID NO. 688;RNA;Artificial Sequence> cucuacagcc
<SEQ ID NO. 689;RNA;Artificial Sequence> ucuuccauagcu
<SEQ ID NO. 690;RNA;Artificial Sequence> auaaucuuccug
<SEQ ID NO. 691;RNA;Artificial Sequence> uaaucuuccugu
<SEQ ID NO. 692;RNA;Artificial Sequence> cuucaugacuug
<SEQ ID NO. 693;RNA;Artificial Sequence> aagagggagaga
<SEQ ID NO. 694;RNA;Artificial Sequence> cgucuccuacca
<SEQ ID NO. 695;RNA;Artificial Sequence> gaucaaucggcc
<SEQ ID NO. 696;RNA;Artificial Sequence> ggacgaacaucc
<SEQ ID NO. 697;RNA;Artificial Sequence> agggucggaac
<SEQ ID NO.698;RNA;Artificial Sequence> ucggaaccca
<SEQ ID NO. 699;RNA;Artificial Sequence> acccaagcuua
<SEQ ID NO. 700;RNA;Artificial Sequence> gaacuuuaagcaac
<SEQ ID NO. 701;RNA;Artificial Sequence> acuauucagug
<SEQ ID NO. 702;RNA;Artificial Sequence> cuauucagugg
<SEQ ID NO. 703;RNA;Artificial Sequence> aaacacagauaac
<SEQ ID NO. 704;RNA;Artificial Sequence> cuuaagaaaaga
741-3635

CA 02677068 2009-09-01
<SEQ ID NO. 705;RNA;Artificial Sequence> cugaaggagugu
<SEQ ID NO. 706;RNA;Artificial Sequence> ucaccgcggg
<SEQ ID NO. 707;RNA;Artificial Sequence> agcagaaauaagcg
<SEQ ID NO. 708;RNA;Artificial Sequence> aagcgugccguu
<SEQ ID NO. 709;RNA;Artificial Sequence> agaaacagucac
<SEQ ID NO.710;RNA;Artificial Sequence> agaggaagaagg
<SEQ ID NO.711;RNA;Artificial Sequence> uguauucaaaauau
<SEQ ID NO. 712;RNA;Artificial Sequence> auuuuccucccuu
<SEQ ID NO. 713;RNA;Artificial Sequence> caaagaaagauag
<SEQ ID NO. 714;RNA;Artificial Sequence> aagaaagauaga
<SEQ ID NO. 715;RNA;Artificial Sequence> gaaagcauuuguu
<SEQ ID NO. 716;RNA;Artificial Sequence> ugaguuaaacgaa
<SEQ ID NO. 717;RNA;Artificial Sequence> acugauacagaa
<SEQ ID NO. 718;RNA;Artificial Sequence> auauuauauaua
<SEQ ID NO. 719;RNA;Artificial Sequence> auuauauauaua
<SEQ ID NO. 720;RNA;Artificial Sequence> ucacuggaugua
<SEQ ID NO. 721 ;RNA;Artificial Sequence> cagggaagagga
<SEQ ID NO. 722;RNA;Artificial Sequence> augaucuuuuuuuug
<SEQ ID NO. 723;RNA;Artificial Sequence> aguucacggcc
<SEQ ID NO. 724;RNA;Artificial Sequence> caccaucacacca
<SEQ ID NO. 725;RNA; Artificial Sequence> ccugcggguuu
<SEQ ID NO. 726;RNA;Artificial Sequence> auccaguuug
<SEQ ID NO. 727;RNA;Artificial Sequence> guuaaggacuucu
<SEQ ID NO. 728;RNA;Artificial Sequence> cagugggacagag
<SEQ ID NO. 729;RNA;Artificial Sequence> aauuuguuauugug
<SEQ ID NO. 730;RNA;Artificial Sequence> uucaaaugcauuu
<SEQ ID NO. 731;RNA;Artificial Sequence> caggaaagcc
<SEQ ID NO. 732;RNA;Artificial Sequence> aggaaagcccu
<SEQ ID NO. 733;RNA; Artificial Sequence> cccagcauggcc
<SEQ ID NO. 734;RNA; Artificial Sequence> cuucucccuga
<SEQ ID NO. 735;RNA;Artificial Sequence> gaagaagcccuu
<SEQ ID NO. 736;RNA; Artificial Sequence> agaagcccuuca
<SEQ ID NO. 737;RNA;Artificial Sequence> gcccuucagcg
<SEQ ID NO. 738;RNA; Artificial Sequence> ccuucagcggc
<SEQ ID NO. 739;RNA;Artificial Sequence> ucagcggccagu
<SEQ ID NO. 740;RNA;Artificial Sequence> ugaaaagcuccg
<SEQ ID NO. 741;RNA;Artificial Sequence> aaaagcuccgg
<SEQ ID NO. 742;RNA;Artificial Sequence> agucaacagucug
<SEQ ID NO. 743;RNA;Artificial Sequence> cagaguucaaaag
<SEQ ID NO. 744;RNA;Artificial Sequence> agaguucaaaagc
<SEQ ID NO. 745;RNA;Artificial Sequence> uucaaaagcccu
<SEQ ID NO. 746;RNA; Artificial Sequence> ucaaaagcccuu
<SEQ ID NO. 747;RNA;Artificial Sequence> aaaagcccuuca
<SEQ ID NO. 748;RNA;Artificial Sequence> aaagcccuucag
<SEQ ID NO. 749;RNA;Artificial Sequence> gugaagccgcucg
<SEQ ID NO. 750;RNA;Artificial Sequence> cacgccagucaa
<SEQ ID NO. 751;RNA;Artificial Sequence> uucuuggugcgug
<SEQ ID NO. 752;RNA; Artificial Sequence> auuggauucaucag
<SEQ ID NO. 75 3;RNA; Artificial Sequence> uggaauaccuaag
<SEQ ID NO. 754;RNA;Artificial Sequence> auuugaggcuca
<SEQ ID NO. 755;RNA;Artificial Sequence> ucuacaauugg
<SEQ ID NO. 756;RNA;Artificial Sequence> uaguuaggagcc
<SEQ ID NO.757;RNA;Artificial Sequence> agucaauauccac
<SEQ ID NO. 758;RNA;Artificial Sequence> auguucagucaca
<SEQ ID NO. 759;RNA;Artificial Sequence> acacacacauac
<SEQ ID NO. 760;RNA;Artificial Sequence> uuccuuuugcuu
<SEQ ID NO. 761;RNA;Artificial Sequence> uuuuaaaguaauuuuu
<SEQ ID NO.762;RNA;Artificial Sequence> caacagucaaugg
<SEQ ID NO. 763;RNA; Artificial Sequence> ucgacaaaccaau
<SEQ ID NO. 764;RNA;Artificial Sequence> acugcuaccacu
<SEQ ID NO. 765;RNA;Artificial Sequence> gcaagcggucuua
<SEQ ID NO. 766;RNA;Artificial Sequence> ggucuuaccggcu
<SEQ ID NO. 767;RNA;Artificial Sequence> gauggguuacc
<SEQ ID NO. 768;RNA;Artificial Sequence> guuaccugcga
<SEQ ID NO. 769;RNA;Artificial Sequence> aaucuugcugag
<SEQ ID NO. 770;RNA;Artificial Sequence> agcauaaaacagu
<SEQ ID NO. 771;RNA;Artificial Sequence> guccuuuauccu
<SEQ ID NO.772;RNA;Artificial Sequence> caacgcaaguug
<SEQ ID NO. 773;RNA;Artificial Sequence> aaacugaaaccau
<SEQ ID NO. 774;RNA;Artificial Sequence> acuuuguuaaauau
<SEQ ID NO. 775;RNA;Artificial Sequence> guauauuaaaaguu
<SEQ ID NO. 776;RNA;Artificial Sequence> guuuugacuuaac
<SEQ ID NO. 777;RNA;Artificial Sequence> gcaaacucagcac
741-3636

CA 02677068 2009-09-01
<SEQ ID NO. 778;RNA;Artificial Sequence> ugcugaccuca
<SEQ ID NO. 779;RNA;Artificial Sequence> uuuauucagaucgc
<SEQ ID NO. 780;RNA;Artificial Sequence> aggguucugggau
<SEQ ID NO.781;RNA;Artificial Sequence> auauuggaaauuaug
<SEQ ID NO. 782;RNA;Artificial Sequence> auggaagcacuag
<SEQ ID NO. 783;RNA;Artificial Sequence> guuuuuaugugga
<SEQ ID NO. 784;RNA;Artificial Sequence> ggaauugguaga
<SEQ ID NO. 785;RNA;Artificial Sequence> uuagacuuggaga
<SEQ ID NO. 786;RNA;Artificial Sequence> uuacaguauucca
<SEQ ID NO. 787;RNA;Artificial Sequence> ccacugaugaauuaa
<SEQ ID NO. 788;RNA;Artificial Sequence> ccacaucaucac
<SEQ ID NO. 789;RNA;Artificial Sequence> cucaccaaacaga
<SEQ ID NO. 790;RNA;Artificial Sequence> ggaacaugaugg
<SEQ ID NO. 791;RNA;Artificial Sequence> cauguagacugc
<SEQ ID NO. 792;RNA;Artificial Sequence> ggaucuauuuaug
<SEQ ID NO. 793;RNA;Artificial Sequence> gcacuauuauca
<SEQ ID NO. 794;RNA;Artificial Sequence> aucaguucugc
<SEQ ID NO. 795;RNA;Artificial Sequence> agauuaaaccuac
<SEQ ID NO. 796;RNA;Artificial Sequence> auaaaauccuucu
<SEQ ID NO.797;RNA;Artiicial Sequence> aaugcuguagac
<SEQ ID NO. 798;RNA;Artificial Sequence> uugauaggaauag
<SEQ ID NO. 799;RNA;Artificial Sequence> aauggcccuga
<SEQ ID NO. 800;RNA;Artificial Sequence> uuccucaagca
<SEQ ID NO. 801;RNA;Artificial Sequence> guucagccca
<SEQ ID NO. 802;RNA;Artificial Sequence> gcugcugaacc
<SEQ ID NO. 803;RNA;Artificial Sequence> aaguucucuuca
<SEQ ID NO. 804;RNA;Artificial Sequence> ccagccuagag
<SEQ ID NO. 805;RNA;Artificial Sequence> cucugugaagugu
<SEQ ID NO. 806;RNA;Artificial Sequence> ugagaaaauuucaa
<SEQ ID NO. 807;RNA;Artificial Sequence> aauccuccuga
<SEQ ID NO. 808;RNA;Artificial Sequence> gugacaucauau
<SEQ ID NO. 809;RNA;Artificial Sequence> aaucuucaucaua
<SEQ ID NO. 810;RNA;Artificial Sequence> gacuagcuauuaa
<SEQ ID NO. 8 1 1;RNA;Artificial Sequence> ucucuacuaaaaau
<SEQ ID NO. 812;RNA;Artificial Sequence> ucuaucucgccu
<SEQ ID NO. 813;RNA;Artificial Sequence> cuucgguccaguu
<SEQ ID NO. 814;RNA;Artificial Sequence> gauguagccgc
<SEQ ID NO. 815;RNA;Artificial Sequence> ugaggagacuug
<SEQ ID NO. 816;RNA;Artificial Sequence> gaguagugagga
<SEQ ID NO. 817;RNA;Artificial Sequence> cagaugaguacaaa
<SEQ ID NO. 818;RNA;Artificial Sequence> guuguuaaugggc
<SEQ ID NO. 819;RNA;Artificial Sequence> uuuuuaauuuauu
<SEQ ID NO. 820;RNA;Artificial Sequence> uauuuaaauaug
<SEQ ID NO. 821;RNA;Artificial Sequence> uauccuuuguuuc
<SEQ ID NO. 822;RNA;Artificial Sequence> cgucuaaguguuug
<SEQ ID NO. 823;RNA;Artificial Sequence> accugugacaaa
<SEQ ID NO. 824;RNA;Artificial Sequence> ccaggcugaauua
<SEQ ID NO. 825;RNA;Artificial Sequence> gucauucuuacaau
<SEQ ID NO. 826;RNA;Artificial Sequence> ucauucuuacaauug
<SEQ ID NO. 827;RNA;Artificial Sequence> cagagaguguac
<SEQ ID NO. 828;RNA;Artificial Sequence> agaacucagcag
<SEQ ID NO.829;RNA;Artificial Sequence> uuuauuuucagua
<SEQ ID NO. 830;RNA;Artificial Sequence> ucuuaaauggaa
<SEQ ID NO. 831;RNA;Artificial Sequence> ugccuaaaauugu
<SEQ ID NO. 832;RNA;Artificial Sequence> agacugugagcu
<SEQ ID NO. 833;RNA;Artificial Sequence> ugcuuuuuauuaau
<SEQ ID NO. 834;RNA;Artificial Sequence> cucuucuuacauu
<SEQ ID NO. 835;RNA;Artificial Sequence> cauuuguaaaaaugu
<SEQ ID NO. 836;RNA;Artificial Sequence> aucuuaauucauauu
<SEQ ID NO. 837;RNA;Artificial Sequence> gaacuaaucauga
<SEQ ID NO. 838;RNA;Artificial Sequence> ucugcucuuggg
<SEQ ID NO. 839;RNA;Artificial Sequence> caguagcuuugag
<SEQ ID NO. 840;RNA;Artificial Sequence> cacguaauauuuca
<SEQ ID NO. 841;RNA;Artificial Sequence> uauucucuucacu
<SEQ ID NO. 842;RNA;Artificial Sequence> cuaaugcuaagaaa
<SEQ ID NO. 843;RNA;Artificial Sequence> gcugaaaaucaa
<SEQ ID NO. 844;RNA;Artificial Sequence> aauaugauuacuuu
<SEQ ID NO. 845;RNA;Artificial Sequence> cauuuuguucuaca
<SEQ ID NO. 846;RNA;Artificial Sequence> cccgggacucuc
<SEQ ID NO. 847;RNA;Artificial Sequence> ccuuuaaaguaaag
<SEQ ID NO. 848;RNA;Artificial Sequence> ucuggaagccugg
<SEQ ID NO. 849;RNA;Artificial Sequence> aaaacaaaagagag
<SEQ ID NO. 850;RNA;Artificial Sequence> aucaguuaugccg
741-3637

CA 02677068 2009-09-01
<SEQ ID NO. 851;RNA;Artificial Sequence> uaaaagaagucca
<SEQ ID NO. 852;RNA;Artificial Sequence> aggugagguua
<SEQ ID NO. 853;RNA;Artificial Sequence> gggaagaggac
<SEQ ID NO. 854;RNA;Artificial Sequence> aagcaaguauugu
<SEQ ID NO. 855;RNA;Artificial Sequence> auuguagcacuc
<SEQ ID NO. 856;RNA;Artificial Sequence> acaaaaccacaaau
<SEQ ID NO. 857;RNA;Artificial Sequence> uaagcccauaca
<SEQ ID NO. 858;RNA;Artificial Sequence> agcccauacag
<SEQ ID NO. 859;RNA;Artificial Sequence> cagaaaccuucc
<SEQ ID NO. 860;RNA;Artificial Sequence> guauaccuac
<SEQ ID NO. 861;RNA;Artificial Sequence> gccaguuuucgga
<SEQ ID NO. 862;RNA;Artificial Sequence> ggaacaggg
<SEQ ID NO. 863;RNA;Artificial Sequence> uuaacuuuccagu
<SEQ ID NO. 864;RNA;Artificial Sequence> aaaguuugguuuug
<SEQ ID NO. 865;RNA;Artificial Sequence> cuucccacugua
<SEQ ID NO. 866;RNA;Artificial Sequence> ugauaccauauga
<SEQ ID NO. 867;RNA;Artificial Sequence> aacaugggcug
<SEQ ID NO. 868;RNA;Artificial Sequence> caacuuuuucaua
<SEQ ID NO. 869;RNA;Artificial Sequence> caugaggccgga
<SEQ ID NO. 870;RNA;Artificial Sequence> acugcauuugu
<SEQ ID NO. 871;RNA;Artificial Sequence> aauguuuacuacc
<SEQ ID NO. 872;RNA;Artificial Sequence> aauuuuuugaugaaa
<SEQ ID NO. 873;RNA;Artificial Sequence> cagugugugaauuu
<SEQ ID NO. 874;RNA;Artificial Sequence> gagcaauguaugu
<SEQ ID NO. 875;RNA;Artificial Sequence> aaagcacauauaua
<SEQ ID NO. 876;RNA;Artificial Sequence> guaauaguuucucc
<SEQ ID NO. 877;RNA;Artificial Sequence> aguuucuccaaau
<SEQ ID NO. 878;RNA;Artificial Sequence> uacuuccuagaaa
<SEQ ID NO. 879;RNA;Artificial Sequence> uacaccauauaug
<SEQ ID NO. 880;RNA;Artificial Sequence> auauaugaauggag
<SEQ ID NO. 881;RNA;Artificial Sequence> acgagaagaagau
<SEQ ID NO. 882;RNA;Artificial Sequence> ucauuuacaggga
<SEQ ID NO. 883;RNA;Artificial Sequence> cauuuacagggac
<SEQ ID NO. 884;RNA;Artificial Sequence> agggaccuga
<SEQ ID NO. 885;RNA;Artificial Sequence> uguuugacugcauc
<SEQ ID NO. 886;RNA;Artificial Sequence> uuugacugcaucg
<SEQ ID NO. 887;RNA;Artificial Sequence> gaguucacaggg
<SEQ ID NO. 888;RNA;Artificial Sequence> ggcaccucugucc
<SEQ ID NO. 889;RNA;Artificial Sequence> gguuugucuuuuuaa
<SEQ ID NO. 890;RNA;Artificial Sequence> uuugucuuuuuaag
<SEQ ID NO. 891;RNA;Artificial Sequence> ccuaaagguuguc
<SEQ ID NO. 892;RNA;Artificial Sequence> aagguugucgac
<SEQ ID NO. 893;RNA;Artificial Sequence> accuggcaauugu
<SEQ ID NO. 894;RNA;Artificial Sequence> aguggugcgagg
<SEQ ID NO. 895;RNA;Artificial Sequence> agagacaugaaau
<SEQ ID NO. 896;RNA;Artificial Sequence> auauauuucucca
<SEQ ID NO. 897;RNA;Artificial Sequence> caugaaggcu
<SEQ ID NO. 898;RNA;Artificial Sequence> gcuggaguggu
<SEQ ID NO. 899;RNA;Artificial Sequence> aggaagagagg
<SEQ ID NO. 900;RNA;Artificial Sequence> cuugcaucgggc
<SEQ ID NO. 901;RNA;Artificial Sequence> auauccuacugug
<SEQ ID NO. 902;RNA;Artificial Sequence> uccuacuguguaa
<SEQ ID NO.903;RNA;Artificial Sequence> ccuuguagugua
<SEQ ID NO. 904;RNA;Artificial Sequence> ucuuuguugauug
<SEQ ID NO. 905;RNA;Artificial Sequence> uuuguugauugaaa
<SEQ ID NO. 906;RNA;Artificial Sequence> uucuuuuucuuccau
<SEQ ID NO. 907;RNA;Artificial Sequence> aaucuuccuucua
<SEQ ID NO. 908;RNA;Artificial Sequence> uugaaugcuucau
<SEQ ID NO. 909;RNA;Artificial Sequence> ugaaugcuucaug
<SEQ ID NO. 910;RNA;Artificial Sequence> aauucuacuuuga
<SEQ ID NO. 911;RNA;Artificial Sequence> agcaacuacagac
<SEQ ID NO. 912;RNA;Artificial Sequence> gaccaaggucaac
<SEQ ID NO. 913;RNA;Artificial Sequence> cgacuaucucgac
<SEQ ID NO. 914;RNA;Artificial Sequence> aaccuucccaaac
<SEQ ID NO. 915;RNA;Artificial Sequence> ccaagcuuagaacu
<SEQ ID NO. 916;RNA;Artificial Sequence> agcuuagaacuuuaa
<SEQ ID NO. 917;RNA;Artificial Sequence> aagaccaccac
<SEQ ID NO. 918;RNA;Artificial Sequence> gcgagaaauaaagu
<SEQ ID NO. 919;RNA;Artificial Sequence> cgagaaauaaaguu
<SEQ ID NO. 920;RNA;Artificial Sequence> aggaaaugaucc
<SEQ ID NO. 921;RNA;Artificial Sequence> gaagaaaugaaac
<SEQ ID NO.922;RNA;Artificial Sequence> guuuccauccucc
<SEQ ID NO. 923;RNA;Artificial Sequence> acugaaaaucuuuga
741-3638

CA 02677068 2009-09-01
<SEQ ID NO. 924;RNA;Artificial Sequence> ugccguucagg
<SEQ ID NO. 925;RNA;Artificial Sequence> caggguccagaag
<SEQ ID NO. 926;RNA;Artificial Sequence> ucaagacugcuug
<SEQ ID NO. 927;RNA;Artificial Sequence> uccaugucuuugg
<SEQ ID NO. 928;RNA;Artificial Sequence> gccugaaacac
<SEQ ID NO. 929;RNA;Artificial Sequence> ucucuguaccuc
<SEQ ID NO. 930;RNA;Artificial Sequence> agcaagacaaga
<SEQ ID NO. 931;RNA;Artificial Sequence> gcaagacaagaaa
<SEQ ID NO. 932;RNA;Artificial Sequence> uguacaagaucc
<SEQ ID NO. 933;RNA;Artificial Sequence> cguacuugcaga
<SEQ ID NO. 934;RNA;Artificial Sequence> cgaucgauacaga
<SEQ ID NO. 935;RNA;Artificial Sequence> uauaaaaauaaau
<SEQ ID NO. 936;RNA;Artificial Sequence> uaaaaauaaauau
<SEQ ID NO.937;RNA;Artificial Sequence> uuugacugcugug
<SEQ ID NO. 938;RNA;Artificial Sequence> ggagaugagagac
<SEQ ID NO. 939;RNA;Artificial Sequence> ucccacuugg
<SEQ ID NO. 940;RNA;Artificial Sequence> guucacggcc
<SEQ ID NO. 941;RNA;Artificial Sequence> accaucacacca
<SEQ ID NO. 942;RNA;Artificial Sequence> cugcggguuu
<SEQ ID NO. 943;RNA;Artificial Sequence> uccaguuug
<SEQ ID NO. 944;RNA;Artificial Sequence> uuaaggacuucu
<SEQ ID NO. 945;RNA;Artificial Sequence> agugggacagag
<SEQ ID NO. 946;RNA;Artificial Sequence> auuuguuauugug
<SEQ ID NO.947;RNA;Artificial Sequence> ucaaaugcauuu
<SEQ ID NO. 948;RNA;Artificial Sequence> aggaaagcc
<SEQ ID NO. 949;RNA;Artificial Sequence> ggaaagcccu
<SEQ ID NO. 950;RNA;Artificial Sequence> ccagcauggcc
<SEQ ID NO. 951;RNA;Artificial Sequence> uucucccuga
<SEQ ID NO. 952;RNA;Artificial Sequence> aagaagcccuu
<SEQ ID NO. 953;RNA;Artificial Sequence> gaagcccuuca
<SEQ ID NO. 954;RNA;Artificial Sequence> cccuucagcg
<SEQ ID NO. 955;RNA;Artificial Sequence> cuucagcggc
<SEQ ID NO. 956;RNA;Artificial Sequence> cagcggccagu
<SEQ ID NO. 957;RNA;Artificial Sequence> gaaaagcuccg
<SEQ ID NO. 958;RNA;Artificial Sequence> aaagcuccgg
<SEQ ID NO.959;RNA;Artificial Sequence> gucaacagucug
<SEQ ID NO. 960;RNA;Artificial Sequence> agaguucaaaag
<SEQ ID NO. 961;RNA;Artificial Sequence> gaguucaaaagc
<SEQ ID NO. 962;RNA; Artificial Sequence> ucaaaagcccu
<SEQ ID NO. 963;RNA;Artificial Sequence> caaaagcccuu
<SEQ ID NO. 964;RNA;Artificial Sequence> aaagcccuuca
<SEQ ID NO. 965;RNA;Artificial Sequence> aagcccuucag
<SEQ ID NO. 966;RNA;Artificial Sequence> ugaagccgcucg
<SEQ ID NO. 967;RNA;Artificial Sequence> acgccagucaa
<SEQ ID NO. 968;RNA;Artificial Sequence> ucuuggugcgug
<SEQ ID NO. 969;RNA;Artificial Sequence> uuggauucaucag
<SEQ ID NO. 970;RNA;Artificial Sequence> ggaauaccuaag
<SEQ ID NO. 971;RNA;Artificial Sequence> uuugaggcuca
<SEQ ID NO. 972;RNA;Artificial Sequence> cuacaauugg
<SEQ ID NO.973;RNA;Artificial Sequence> aguuaggagcc
<SEQ ID NO. 974;RNA;Artificial Sequence> gucaauauccac
<SEQ ID NO. 975;RNA;Artificial Sequence> uguucagucaca
<SEQ ID NO. 976;RNA;Artificial Sequence> cacacacauac
<SEQ ID NO. 977;RNA;Artificial Sequence> uccuuuugcuu
<SEQ ID NO. 978;RNA;Artificial Sequence> uuuaaaguaauuuuu
<SEQ ID NO. 979;RNA;Artificial Sequence> aacagucaaugg
<SEQ ID NO. 980;RNA;Artificial Sequence> cgacaaaccaau
<SEQ ID NO. 981;RNA;Artificial Sequence> cugcuaccacu
<SEQ ID NO. 982;RNA;Artificial Sequence> caagcggucuua
<SEQ ID NO. 983;RNA;Artificial Sequence> gucuuaccggcu
<SEQ ID NO. 984;RNA;Artificial Sequence> auggguuacc
<SEQ ID NO. 985;RNA;Artificial Sequence> uuaccugcga
<SEQ ID NO. 986;RNA;Artificial Sequence> aucuugcugag
<SEQ ID NO. 987;RNA; Artificial Sequence> gcauaaaacagu
<SEQ ID NO. 988;RNA; Artificial Sequence> uccuuuauccu
<SEQ ID NO. 989;RNA;Artificial Sequence> aacgcaaguug
<SEQ ID NO. 990;RNA;Artificial Sequence> aacugaaaccau
<SEQ ID NO. 991;RNA;Artificial Sequence> cuuuguuaaauau
<SEQ ID NO. 992;RNA;Artificial Sequence> uauauuaaaaguu
<SEQ ID NO. 993;RNA;Artificial Sequence> uuuugacuuaac
<SEQ ID NO. 994;RNA;Artificial Sequence> caaacucagcac
<SEQ ID NO. 995;RNA;Artificial Sequence> gcugaccuca
<SEQ ID NO. 996;RNA;Artificial Sequence> uuauucagaucgc
741-3639

CA 02677068 2009-09-01
<SEQ ID NO. 997;RNA;Artificial Sequence> ggguucugggau
<SEQ ID NO. 998;RNA;Artificial Sequence> uauuggaaauuaug
<SEQ ID NO. 999;RNA;Artificial Sequence> uggaagcacuag
<SEQ ID NO. I000;RNA;Artificial Sequence> uuuuuaugugga
<SEQ ID NO. 1001;RNA;Artificial Sequence> gaauugguaga
<SEQ ID NO. 1002;RNA;Artificial Sequence> uagacuuggaga
<SEQ ID NO. 1003;RNA;Artificial Sequence> uacaguauucca
<SEQ ID NO. 1004;RNA;Artificial Sequence> cacugaugaauuaa
<SEQ ID NO. 1005;RNA;Artificial Sequence> cacaucaucac
<SEQ ID NO. 1006;RNA;Artificial Sequence> ucaccaaacaga
<SEQ ID NO. 1007;RNA;Artificial Sequence> gaacaugaugg
<SEQ ID NO. 1008;RNA;Artificial Sequence> auguagacugc
<SEQ ID NO. 1009;RNA;Artificial Sequence> gaucuauuuaug
<SEQ ID NO. 1010;RNA;Artificial Sequence> cacuauuauca
<SEQ ID NO. 1011;RNA;Artificial Sequence> ucaguucugc
<SEQ ID NO. 1012;RNA;Artificial Sequence> gauuaaaccuac
<SEQ ID NO. 1013;RNA;Artificial Sequence> uaaaauccuucu
<SEQ ID NO. 1014;RNA;Artificial Sequence> augcuguagac
<SEQ ID NO. 1015;RNA;Artificial Sequence> ugauaggaauag
<SEQ ID NO. 1016;RNA;Artificial Sequence> auggcccuga
<SEQ ID NO. 1017;RNA;Artificial Sequence> uccucaagca
<SEQ ID NO. 1018;RNA;Artificial Sequence> uucagccca
<SEQ ID NO. 1019;RNA;Artificial Sequence> cugcugaacc
<SEQ ID NO. 1020;RNA;Artificial Sequence> aguucucuuca
<SEQ ID NO. 1021;RNA;Artificial Sequence> cagccuagag
<SEQ ID NO. 1022;RNA;Artificial Sequence> ucugugaagugu
<SEQ ID NO. 1023;RNA;Artificial Sequence> gagaaaauuucaa
<SEQ ID NO. 1024;RNA;Artificial Sequence> auccuccuga
<SEQ ID NO. 1025;RNA;Artificial Sequence> ugacaucauau
<SEQ ID NO. 1026;RNA;Artificial Sequence> aucuucaucaua
<SEQ ID NO. 1027;RNA;Artificial Sequence> acuagcuauuaa
<SEQ ID NO. 1028;RNA;Artificial Sequence> cucuacuaaaaau
<SEQ ID NO. 1029;RNA;Artificial Sequence> cuaucucgccu
<SEQ ID NO. 1030;RNA;Artificial Sequence> uucgguccaguu
<SEQ ID NO. 1031;RNA;Artificial Sequence> auguagccgc
<SEQ ID NO. 1032;RNA;Artificial Sequence> gaggagacuug
<SEQ ID NO. 1033;RNA;Artificial Sequence> aguagugagga
<SEQ ID NO. 1034;RNA;Artificial Sequence> agaugaguacaaa
<SEQ ID NO. 1035;RNA;Artificial Sequence> uuguuaaugggc
<SEQ ID NO. 1036;RNA;Artificial Sequence> uuuuaauuuauu
<SEQ ID NO. 1037;RNA;Artificial Sequence> auuuaaauaug
<SEQ ID NO. 1038;RNA;Artificial Sequence> auccuuuguuuc
<SEQ ID NO. 1039;RNA;Artificial Sequence> gucuaaguguuug
<SEQ ID NO. 1040;RNA;Artificial Sequence> ccugugacaaa
<SEQ ID NO. 1041;RNA;Artificial Sequence> caggcugaauua
<SEQ ID NO. 1042;RNA;Artificial Sequence> ucauucuuacaau
<SEQ ID NO. 1043;RNA;Artificial Sequence> cauucuuacaauug
<SEQ ID NO. 1044;RNA;Artificial Sequence> agagaguguac
<SEQ ID NO. 1045;RNA;Artificial Sequence> gaacucagcag
<SEQ ID NO. 1046;RNA;Artificial Sequence> uuauuuucagua
<SEQ ID NO. 1047;RNA;Artificial Sequence> cuuaaauggaa
<SEQ ID NO. 1048;RNA;Artificial Sequence> gccuaaaauugu
<SEQ ID NO. 1049;RNA;Artificial Sequence> acuaacaucugg
<SEQ ID NO. 1050;RNA;Artificial Sequence> gacugugagcu
<SEQ ID NO. 1051;RNA;Artificial Sequence> gcuuuuuauuaau
<SEQ ID NO. 1052;RNA;Artificial Sequence> ucuucuuacauu
<SEQ ID NO. 1053;RNA;Artificial Sequence> auuuguaaaaaugu
<SEQ ID NO. 1054;RNA;Artificial Sequence> ucuuaauucauauu
<SEQ ID NO. 1055;RNA;Artificial Sequence> aacuaaucauga
<SEQ ID NO. 1056;RNA;Artificial Sequence> cugcucuuggg
<SEQ ID NO. 1057;RNA;Artificial Sequence> aguagcuuugag
<SEQ ID NO. 1058;RNA;Artificial Sequence> acguaauauuuca
<SEQ ID NO. 1059;RNA;Artificial Sequence> auucucuucacu
<SEQ ID NO. 1060;RNA;Artificial Sequence> uaaugcuaagaaa
<SEQ ID NO. 1061;RNA;Artificial Sequence> cugaaaaucaa
<SEQ ID NO. 1062;RNA;Artificial Sequence> auaugauuacuuu
<SEQ ID NO. 1063;RNA;Artificial Sequence> auuuuguucuaca
<SEQ ID NO. 1064;RNA;Artificial Sequence> ccgggacucuc
<SEQ ID NO. 1065;RNA;Artificial Sequence> cuuuaaaguaaag
<SEQ ID NO. 1066;RNA;Artificial Sequence> cuggaagccugg
<SEQ ID NO. 1067;RNA;Artificial Sequence> aaacaaaagagag
<SEQ ID NO. 1068;RNA;Artificial Sequence> ucaguuaugccg
<SEQ ID NO. 1069;RNA;Artificial Sequence> aaaagaagucca
741-3640

CA 02677068 2009-09-01
<SEQ ID NO. 1070;RNA;Artificial Sequence> ggugagguua
<SEQ ID NO. 1071;RNA;Artificial Sequence> ggaagaggac
<SEQ ID NO. 1072;RNA;Artificial Sequence> agcaaguauugu
<SEQ ID NO. 1073;RNA;Artificial Sequence> uuguagcacuc
<SEQ ID NO. 1074;RNA;Artificial Sequence> caaaaccacaaau
<SEQ ID NO. 1075;RNA;Artificial Sequence> aagcccauaca
<SEQ ID NO. 1076;RNA;Artificial Sequence> gcccauacag
<SEQ ID NO. 1077;RNA;Artificial Sequence> agaaaccuucc
<SEQ ID NO. 1078;RNA;Artificial Sequence> uauaccuac
<SEQ ID NO. 1079;RNA;Artificial Sequence> ccaguuuucgga
<SEQ ID NO. 1080;RNA;Artificial Sequence> gaacaggg
<SEQ ID NO. 1081;RNA;Artificial Sequence> uaacuuuccagu
<SEQ ID NO. 1082;RNA;Artificial Sequence> aaguuugguuuug
<SEQ ID NO. 1083;RNA;Artificial Sequence> uucccacugua
<SEQ ID NO. 1084;RNA;Artificial Sequence> gauaccauauga
<SEQ ID NO. 1085;RNA;Artificial Sequence> acaugggcug
<SEQ ID NO. 1086;RNA;Artificial Sequence> aacuuuuucaua
<SEQ ID NO. 1087;RNA;Artificial Sequence> augaggccgga
<SEQ ID NO. 1088;RNA;Artificial Sequence> cugcauuugu
<SEQ ID NO. 1089;RNA;Artificial Sequence> auguuuacuacc
<SEQ ID NO. 1090;RNA;Artificial Sequence> auuuuuugaugaaa
<SEQ ID NO. 1091;RNA;Artificial Sequence> agugugugaauuu
<SEQ ID NO. 1092;RNA;Artificial Sequence> agcaauguaugu
<SEQ ID NO. 1093;RNA;Artificial Sequence> aagcacauauaua
<SEQ ID NO. 1094;RNA;Artificial Sequence> uaauaguuucucc
<SEQ ID NO. 1095;RNA;Artificial Sequence> guuucuccaaau
<SEQ ID NO. 1096;RNA;Artificial Sequence> acuuccuagaaa
<SEQ ID NO. 1097;RNA;Artificial Sequence> acaccauauaug
<SEQ ID NO. 1098;RNA;Artificial Sequence> uauaugaauggag
<SEQ ID NO. 1099;RNA;Artificial Sequence> cauuuacaggga
<SEQ ID NO. 1100;RNA;Artificial Sequence> auuuacagggac
<SEQ ID NO. 1101;RNA;Artificial Sequence> gggaccuga
<SEQ ID NO. 1102;RNA;Artificial Sequence> guuugacugcauc
<SEQ ID NO. 1103;RNA;Artificial Sequence> uugacugcaucg
<SEQ ID NO. 1104;RNA;Artificial Sequence> aguucacaggg
<SEQ ID NO. 1105;RNA;Artificial Sequence> gcaccucugucc
<SEQ ID NO. 1106;RNA;Artificial Sequence> guuugucuuuuuaa
<SEQ ID NO. 1107;RNA;Artificial Sequence> uugucuuuuuaag
<SEQ ID NO. 1108;RNA;Artificial Sequence> cuaaagguuguc
<SEQ ID NO. 1109;RNA;Artificial Sequence> agguugucgac
<SEQ ID NO. 1110;RNA;Artificial Sequence> ccuggcaauugu
<SEQ ID NO. 1111;RNA;Artificial Sequence> guggugcgagg
<SEQ ID NO. 11 12;RNA;Artificial Sequence> gagacaugaaau
<SEQ ID NO. 11 13;RNA;Artificial Sequence> uauauuucucca
<SEQ ID NO. 11 14;RNA;Artificial Sequence> augaaggcu
<SEQ ID NO. 1115;RNA;Artificial Sequence> cuggaguggu
<SEQ ID NO. 11 16;RNA;Artificial Sequence> ggaagagagg
<SEQ ID NO. 11 17;RNA;Artificial Sequence> uugcaucgggc
<SEQ ID NO. 11 18;RNA;Artificial Sequence> uauccuacugug
<SEQ ID NO. 11 19;RNA;Artificial Sequence> ccuacuguguaa
<SEQ ID NO. 1120;RNA;Artificial Sequence> cuuguagugua
<SEQ ID NO. 1121;RNA;Artificial Sequence> cuuuguugauug
<SEQ ID NO. 1122;RNA;Artificial Sequence> uuguugauugaaa
<SEQ ID NO. 1123;RNA;Artificial Sequence> ucuuuuucuuccau
<SEQ ID NO. 1124;RNA;Artificial Sequence> aucuuccuucua
<SEQ ID NO. 1125;RNA;Artificial Sequence> ugaaugcuucau
<SEQ ID NO. 1126;RNA;Artificial Sequence> gaaugcuucaug
<SEQ ID NO. 1127;RNA;Artificial Sequence> auucuacuuuga
<SEQ ID NO. 1128;RNA;Artificial Sequence> gcaacuacagac
<SEQ ID NO. 1129;RNA;Artificial Sequence> accaaggucaac
<SEQ ID NO. 1130;RNA;Artificial Sequence> gacuaucucgac
<SEQ ID NO. 1131;RNA;Artificial Sequence> accuucccaaac
<SEQ ID NO. 1132;RNA;Artificial Sequence> caagcuuagaacu
<SEQ ID NO. 1133;RNA;Artificial Sequence> gcuuagaacuuuaa
<SEQ ID NO. 1134;RNA;Artificial Sequence> aacuuuaagcaac
<SEQ ID NO. 1135;RNA;Artificial Sequence> agaccaccac
<SEQ ID NO. 1136;RNA;Artificial Sequence> cgagaaauaaagu
<SEQ ID NO. 1137;RNA;Artificial Sequence> gagaaauaaaguu
<SEQ ID NO. 1138;RNA;Artificial Sequence> ggaaaugaucc
<SEQ ID NO. 1139;RNA;Artificial Sequence> aagaaaugaaac
<SEQ ID NO. 1140;RNA;Artificial Sequence> uuuccauccucc
<SEQ ID NO. 1141;RNA;Artificial Sequence> cugaaaaucuuuga
<SEQ ID NO. 1142;RNA;Artificial Sequence> gccguucagg
741-3641

CA 02677068 2009-09-01
<SEQ ID NO. 1143;RNA;Artificial Sequence> aggguccagaag
<SEQ ID NO. 1144;RNA;Artificial Sequence> caagacugcuug
<SEQ ID NO. 1145;RNA;Artificial Sequence> ccaugucuuugg
<SEQ ID NO. 1146;RNA;Artificial Sequence> ccugaaacac
<SEQ ID NO. 1147;RNA;Artificial Sequence> cucuguaccuc
<SEQ ID NO. 1148;RNA;Artificial Sequence> gcaagacaaga
<SEQ ID NO. 1149;RNA;Artificial Sequence> caagacaagaaa
<SEQ ID NO. 1150;RNA;Artificial Sequence> guacaagaucc
<SEQ ID NO. 1151;RNA;Artificial Sequence> guacuugcaga
<SEQ ID NO. 1152;RNA;Artificial Sequence> gaucgauacaga
<SEQ ID NO. 1153;RNA;Artificial Sequence> auaaaaauaaau
<SEQ ID NO. 1154;RNA;Artificial Sequence> aaaaauaaauau
<SEQ ID NO. 1155;RNA;Artificial Sequence> uugacugcugug
<SEQ ID NO. 1156;RNA;Artificial Sequence> gagaugagagac
<SEQ ID NO. 1157;RNA;Artificial Sequence> cccacuugg
<SEQ ID NO. 1158;RNA;Homo sapiens>
CACAGGCUGAGCAGUCAGGCCCACAGCAUCUGACCCCAGGCCCAGCUCGUCCUGGCUGGCCUGGGUCGGCC
UCUGGAGUAUGGUCUGGCGGGUGCCCCCUUUCUUGCUCCCCAUCCUCUUCUUGGCUUCUCAUGUGGGCGCGGCGGUG
GACCUGACGCUGCUGGCCAACCUGCGGCUCACGGACCCCCAGCGCUUCUUCCUGACUUGCGUGUCUGGGGAGGCCGG
GGCGGGGAGGGGCUCGGACGCCUGGGGCCCGCCCCUGCUGCUGGAGAAGGACGACCGUAUCGUGCGCACCCCGCCCG
GGCCACCCCUGCGCCUGGCGCGCAACGGUUCGCACCAGGUCACGCUUCGCGGCUUCUCCAAGCCCUCGGACCUCGUGG
GCGUCUUCUCCUGCGUGGGCGGUGCUGGGGCGCGGCGCACGCGCGUCAUCUACGUGCACAACAGCCCUGGAGCCCAC
CUGCUUCCAGACAAGGUCACACACACUGUGAACAAAGGUGACACCGCUGUACUUUCUGCACGUGUGCACAAGGAGAA
GCAGACAGACGUGAUCUGGAAGAGCAACGGAUCCUACUUCUACACCCUGGACUGGCAUGAAGCCCAGGAUGGGCGGU
UCCUGCUGCAGCUCCCAAAUGUGCAGCCACCAUCGAGCGGCAUCUACAGUGCCACUUACCUGGAAGCCAGCCCCCUG
GGCAGCGCCUUCUUUCGGCUCAUCGUGCGGGGUUGUGGGGCUGGGCGCUGGGGGCCAGGCUGUACCAAGGAGUGCCC
AGGUUGCCUACAUGGAGGUGUCUGCCACGACCAUGACGGCGAAUGUGUAUGCCCCCCUGGCUUCACUGGCACCCGCU
GUGAACAGGCCUGCAGAGAGGGCCGUUUUGGGCAGAGCUGCCAGGAGCAGUGCCCAGGCAUAUCAGGCUGCCGGGGC
CUCACCUUCUGCCUCCCAGACCCCUAUGGCUGCUCUUGUGGAUCUGGCUGGAGAGGAAGCCAGUGCCAAGAAGCUUG
UGCCCCUGGUCAUUUUGGGGCUGAUUGCCGACUCCAGUGCCAGUGUCAGAAUGGUGGCACUUGUGACCGGUUCAGUG
GUUGUGUCUGCCCCUCUGGGUGGCAUGGAGUGCACUGUGAGAAGUCAGACCGGAUCCCCCAGAUCCUCAACAUGGCC
UCAGAACUGGAGUUCAACUUAGAGACGAUGCCCCGGAUCAACUGUGCAGCUGCAGGGAACCCCUUCCCCGUGCGGGG
CAGCAUAGAGCUACGCAAGCCAGACGGCACUGUGCUCCUGUCCACCAAGGCCAUUGUGGAGCCAGAGAAGACCACAG
CUGAGUUCGAGGUGCCCCGCUUGGUUCUUGCGGACAGUGGGUUCUGGGAGUGCCGUGUGUCCACAUCUGGCGGCCAA
GACAGCCGGCGCUUCAAGGUCAAUGUGAAAGUGCCCCCCGUGCCCCUGGCUGCACCUCGGCUCCUGACCAAGCAGAG
CCGCCAGCUUGUGGUCUCCCCGCUGGUCUCGUUCUCUGGGGAUGGACCCAUCUCCACUGUCCGCCUGCACUACCGGCC
CCAGGACAGUACCAUGGACUGGUCGACCAUUGUGGUGGACCCCAGUGAGAACGUGACGUUAAUGAACCUGAGGCCAA
AGACAGGAUACAGUGUUCGUGUGCAGCUGAGCCGGCCAGGGGAAGGAGGAGAGGGGGCCUGGGGGCCUCCCACCCUC
AUGACCACAGACUGUCCUGAGCCUUUGUUGCAGCCGUGGUUGGAGGGCUGGCAUGUGGAAGGCACUGACCGGCUGCG
AGUGAGCUGGUCCUUGCCCUUGGUGCCCGGGCCACUGGUGGGCGACGGUUUCCUGCUGCGCCUGUGGGACGGGACAC
GGGGGCAGGAGCGGCGGGAGAACGUCUCAUCCCCCCAGGCCCGCACUGCCCUCCUGACGGGACUCACGCCUGGCACCC
ACUACCAGCUGGAUGUGCAGCUCUACCACUGCACCCUCCUGGGCCCGGCCUCGCCCCCUGCACACGUGCUUCUGCCCC
CCAGUGGGCCUCCAGCCCCCCGACACCUCCACGCCCAGGCCCUCUCAGACUCCGAGAUCCAGCUGACAUGGAAGCACC
CGGAGGCUCUGCCUGGGCCAAUAUCCAAGUACGUUGUGGAGGUGCAGGUGGCUGGGGGUGCAGGAGACCCACUGUG
GAUAGACGUGGACAGGCCUGAGGAGACAAGCACCAUCAUCCGUGGCCUCAACGCCAGCACGCGCUACCUCUUCCGCA
UGCGGGCCAGCAUUCAGGGGCUCGGGGACUGGAGCAACACAGUAGAAGAGUCCACCCUGGGCAACGGGCUGCAGGCU
GAGGGCCCAGUCCAAGAGAGCCGGGCAGCUGAAGAGGGCCUGGAUCAGCAGCUGAUCCUGGCGGUGGUGGGCUCCGU
GUCUGCCACCUGCCUCACCAUCCUGGCCGCCCUUUUAACCCUGGUGUGCAUCCGCAGAAGCUGCCUGCAUCGGAGAC
GCACCUUCACCUACCAGUCAGGCUCGGGCGAGGAGACCAUCCUGCAGUUCAGCUCAGGGACCUUGACACUUACCCGG
CGGCCAAAACUGCAGCCCGAGCCCCUGAGCUACCCAGUGCUAGAGUGGGAGGACAUCACCUUUGAGGACCUCAUCGG
GGAGGGGAACUUCGGCCAGGUCAUCCGGGCCAUGAUCAAGAAGGACGGGCUGAAGAUGAACGCAGCCAUCAAAAUGC
UGAAAGAGUAUGCCUCUGAAAAUGACCAUCGUGACUUUGCGGGAGAACUGGAAGUUCUGUGCAAAUUGGGGCAUCA
CCCCAACAUCAUCAACCUCCUGGGGGCCUGUAAGAACCGAGGUUACUUGUAUAUCGCUAUUGAAUAUGCCCCCUACG
GGAACCUGCUAGAUUUUCUGCGGAAAAGCCGGGUCCUAGAGACUGACCCAGCUUUUGCUCGAGAGCAUGGGACAGCC
UCUACCCUUAGCUCCCGGCAGCUGCUGCGUUUCGCCAGUGAUGCGGCCAAUGGCAUGCAGUACCUGAGUGAGAAGCA
GUUCAUCCACAGGGACCUGGCUGCCCGGAAUGUGCUGGUCGGAGAGAACCUAGCCUCCAAGAUUGCAGACUUCGGCC
UUUCUCGGGGAGAGGAGGUUUAUGUGAAGAAGACGAUGGGGCGUCUCCCUGUGCGCUGGAUGGCCAUUGAGUCCCU
GAACUACAGUGUCUAUACCACCAAGAGUGAUGUCUGGUCCUUUGGAGUCCUUCUUUGGGAGAUAGUGAGCCUUGGA
GGUACACCCUACUGUGGCAUGACCUGUGCCGAGCUCUAUGAAAAGCUGCCCCAGGGCUACCGCAUGGAGCAGCCUCG
AAACUGUGACGAUGAAGUGUACGAGCUGAUGCGUCAGUGCUGGCGGGACCGUCCCUAUGAGCGACCCCCCUUUGCCC
AGAUUGCGCUACAGCUAGGCCGCAUGCUGGAAGCCAGGAAGGCCUAUGUGAACAUGUCGCUGUUUGAGAACUUCACU
UACGCGGGCAUUGAUGCCACAGCUGAGGAGGCCUGAGCUGCCAUCCAGCCAGAACGUGGCUCUGCUGGCCGGAGCAA
ACUCUGCUGUCUAACCUGUGACCAGUCUGACCCUUACAGCCUCUGACUUAAGCUGCCUCAAGGAAUUUUUUUAACUU
AAGGGAGAAAAAAAGGGAUCUGGGGAUGGGGUGGGCUUAGGGGAACUGGGUUCCCAUGCUUUGUAGGUGUCUCAUA
GCUAUCCUGGGCAUCCUUCUUUCUAGUUCAGCUGCCCCACAGGUGUGUUUCCCAUCCCACUGCUCCCCCAACACAAAC
CCCCACUCCAGCUCCUUCGCUUAAGCCAGCACUCACACCACUAACAUGCCCUGUUCAGCUACUCCCACUCCCGGCCUG
UCAUUCAGAAAAAAAUAAAUGUUCUAAUAAGCUCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1159;RNA;Artificial Sequence> cacaggcugagcagucagg
<SEQ ID NO. 1160;RNA;Artificial Sequence> gcccacagcaucugacccc
<SEQ ID NO. 1161;RNA;Artificial Sequence> caggcccagcucguccugg
<SEQ ID NO. 1162;RNA;Artificial Sequence> gcuggccugggucggccuc
<SEQ ID NO. 1163;RNA;Artificial Sequence> cuggaguauggucuggcgg
741-3642

CA 02677068 2009-09-01
<SEQ ID NO. 1164;RNA;Artificial Sequence> ggugcccccuuucuugcuc
<SEQ ID NO. 1165;RNA;Artificial Sequence> ccccauccucuucuuggcu
<SEQ ID NO. 1166;RNA;Artificial Sequence> uucucaugugggcgcggcg
<SEQ ID NO. 1167;RNA;Artificial Sequence> gguggaccugacgcugcug
<SEQ ID NO. 1168;RNA;Artificial Sequence> ggccaaccugcggcucacg
<SEQ ID NO. 1169;RNA;Artificial Sequence> ggacccccagcgcuucuuc
<SEQ ID NO. 1170;RNA;Artificial Sequence> ccugacuugcgugucuggg
<SEQ ID NO. 1171;RNA;Artificial Sequence> ggaggccggggcggggagg
<SEQ ID NO. 1172;RNA;Artificial Sequence> gggcucggacgccuggggc
<SEQ ID NO. 1173;RNA;Artificial Sequence> cccgccccugcugcuggag
<SEQ ID NO. 1174;RNA;Artificial Sequence> gaaggacgaccguaucgug
<SEQ ID NO. 1175;RNA;Artificial Sequence> gcgcaccccgcccgggcca
<SEQ ID NO. 1176;RNA;Artificial Sequence> accccugcgccuggcgcgc
<SEQ ID NO. 1177;RNA;Artificial Sequence> caacgguucgcaccagguc
<SEQ ID NO. 1178;RNA;Artificial Sequence> cacgcuucgcggcuucucc
<SEQ ID NO. 1179;RNA;Artificial Sequence> caagcccucggaccucgug
<SEQ ID NO. 11 80;RNA;Artificial Sequence> gggcgucuucuccugcgug
<SEQ ID NO. 1181;RNA;Artificial Sequence> gggcggugcuggggcgcgg
<SEQ ID NO. 1182;RNA;Artificial Sequence> gcgcacgcgcgucaucuac
<SEQ ID NO. 1183;RNA;Artificial Sequence> cgugcacaacagcccugga
<SEQ ID NO. 1184;RNA;Artificial Sequence> agcccaccugcuuccagac
<SEQ ID NO. 1185;RNA;Artificial Sequence> caaggucacacacacugug
<SEQ ID NO. 1186;RNA;Artificial Sequence> gaacaaaggugacaccgcu
<SEQ ID NO. 1187;RNA;Artificial Sequence> uguacuuucugcacgugug
<SEQ ID NO. 1188;RNA;Artificial Sequence> gcacaaggagaagcagaca
<SEQ ID NO. 1189;RNA;Artificial Sequence> agacgugaucuggaagagc
<SEQ ID NO. 1190;RNA;Artificial Sequence> caacggauccuacuucuac
<SEQ ID NO. 1191;RNA;Artificial Sequence> cacccuggacuggcaugaa
<SEQ ID NO. 1192;RNA;Artificial Sequence> agcccaggaugggcgguuc
<SEQ ID NO. 1193;RNA;Artificial Sequence> ccugcugcagcucccaaau
<SEQ ID NO. 1194;RNA;Artificial Sequence> ugugcagccaccaucgagc
<SEQ ID NO. 1195;RNA;Artificial Sequence> cggcaucuacagugccacu
<SEQ ID NO. 1196;RNA;Artificial Sequence> uuaccuggaagccagcccc
<SEQ ID NO. 1197;RNA;Artificial Sequence> ccugggcagcgccuucuuu
<SEQ ID NO. 1198;RNA;Artificial Sequence> ucggcucaucgugcggggu
<SEQ ID NO. 1199;RNA;Artificial Sequence> uuguggggcugggcgcugg
<SEQ ID NO. 1200;RNA;Artificial Sequence> ggggccaggcuguaccaag
<SEQ ID NO. 1201;RNA;Artificial Sequence> ggagugcccagguugccua
<SEQ ID NO. 1202;RNA;Artificial Sequence> acauggaggugucugccac
<SEQ ID NO. 1203;RNA;Artificial Sequence> cgaccaugacggcgaaugu
<SEQ ID NO. 1204;RNA;Artificial Sequence> uguaugccccccuggcuuc
<SEQ ID NO. 1205;RNA;Artificial Sequence> cacuggcacccgcugugaa
<SEQ ID NO. 1206;RNA;Artificial Sequence> acaggccugcagagagggc
<SEQ ID NO. 1207;RNA;Artificial Sequence> ccguuuugggcagagcugc
<SEQ ID NO. 1208;RNA;Artificial Sequence> ccaggagcagugcccaggc
<SEQ ID NO. 1209;RNA;Artificial Sequence> cauaucaggcugccggggc
<SEQ ID NO. 1210;RNA;Artificial Sequence> ccucaccuucugccuccca
<SEQ ID NO. 1211;RNA;Artificial Sequence> agaccccuauggcugcucu
<SEQ ID NO. 1212;RNA;Artificial Sequence> uuguggaucuggcuggaga
<SEQ ID NO. 1213;RNA;Artificial Sequence> aggaagccagugccaagaa
<SEQ ID NO. 1214;RNA;Artificial Sequence> agcuugugccccuggucau
<SEQ ID NO. 1215;RNA;Artificial Sequence> uuuuggggcugauugccga
<SEQ ID NO. 1216;RNA;Artificial Sequence> acuccagugccagugucag
<SEQ ID NO. 1217;RNA;Artificial Sequence> gaaugguggcacuugugac
<SEQ ID NO. 1218;RNA;Artificial Sequence> ccgguucagugguuguguc
<SEQ ID NO. 1219;RNA;Artificial Sequence> cugccccucuggguggcau
<SEQ ID NO. 1220;RNA;Artificial Sequence> uggagugcacugugagaag
<SEQ ID NO. 1221;RNA;Artificial Sequence> gucagaccggaucccccag
<SEQ ID NO. 1222;RNA;Artificial Sequence> gauccucaacauggccuca
<SEQ ID NO. 1223;RNA;Artificial Sequence> agaacuggaguucaacuua
<SEQ ID NO. 1224;RNA;Artificial Sequence> agagacgaugccccggauc
<SEQ ID NO. 1225;RNA;Artificial Sequence> caacugugcagcugcaggg
<SEQ ID NO. 1226;RNA;Artificial Sequence> gaaccccuuccccgugcgg
<SEQ ID NO. 1227;RNA;Artificial Sequence> gggcagcauagagcuacgc
<SEQ ID NO. 1228;RNA;Artificial Sequence> caagccagacggcacugug
<SEQ ID NO. 1229;RNA;Artificial Sequence> gcuccuguccaccaaggcc
<SEQ ID NO. 1230;RNA;Artificial Sequence> cauuguggagccagagaag
<SEQ ID NO. 1231;RNA;Artificial Sequence> gaccacagcugaguucgag
<SEQ ID NO. 1232;RNA;Artificial Sequence> ggugccccgcuugguucuu
<SEQ ID NO. 1233;RNA;Artificial Sequence> ugcggacaguggguucugg
<SEQ ID NO. 1234;RNA;Artificial Sequence> ggagugccguguguccaca
<SEQ ID NO. 1235;RNA;Artificial Sequence> aucuggcggccaagacagc
<SEQ ID NO. 1236;RNA;Artificial Sequence> ccggcgcuucaaggucaau
741-3643

CA 02677068 2009-09-01
<SEQ ID NO. 1237;RNA;Artificial Sequence> ugugaaagugccccccgug
<SEQ ID NO. 1238;RNA;Artificial Sequence> gccccuggcugcaccucgg
<SEQ ID NO. 1239;RNA;Artificial Sequence> gcuccugaccaagcagagc
<SEQ ID NO. 1240;RNA;Artificial Sequence> ccgccagcuuguggucucc
<SEQ ID NO. 1241;RNA;Artificial Sequence> cccgcuggucucguucucu
<SEQ ID NO. 1242;RNA;Artificial Sequence> uggggauggacccaucucc
<SEQ ID NO. 1243;RNA;Artificial Sequence> cacuguccgccugcacuac
<SEQ ID NO. 1244;RNA;Artificial Sequence> ccggccccaggacaguacc
<SEQ ID NO. 1245;RNA;Artificial Sequence> cauggacuggucgaccauu
<SEQ ID NO. 1246;RNA;Artificial Sequence> ugugguggaccccagugag
<SEQ ID NO. 1247;RNA;Artificial Sequence> gaacgugacguuaaugaac
<SEQ ID NO. 1248;RNA;Artificial Sequence> ccugaggccaaagacagga
<SEQ ID NO. 1249;RNA;Artificial Sequence> auacaguguucgugugcag
<SEQ ID NO. 1250;RNA;Artificial Sequence> gcugagccggccaggggaa
<SEQ ID NO. 1251;RNA;Artificial Sequence> aggaggagagggggccugg
<SEQ ID NO. 1252;RNA;Artificial Sequence> ggggccucccacccucaug
<SEQ ID NO. 1253;RNA;Artificial Sequence> gaccacagacuguccugag
<SEQ ID NO. 1254;RNA;Artificial Sequence> gccuuuguugcagccgugg
<SEQ ID NO. 1255;RNA;Artificial Sequence> guuggagggcuggcaugug
<SEQ ID NO. 1256;RNA;Artificial Sequence> ggaaggcacugaccggcug
<SEQ ID NO. 1257;RNA;Artificial Sequence> gcgagugagcugguccuug
<SEQ ID NO. 1258;RNA;Artificial Sequence> gcccuuggugcccgggcca
<SEQ ID NO. 1259;RNA;Artificial Sequence> acuggugggcgacgguuuc
<SEQ ID NO. 1260;RNA;Artificial Sequence> ccugcugcgccugugggac
<SEQ ID NO. 1261;RNA;Artificial Sequence> cgggacacgggggcaggag
<SEQ ID NO. 1262;RNA;Artificial Sequence> gcggcgggagaacgucuca
<SEQ ID NO. 1263;RNA;Artificial Sequence> auccccccaggcccgcacu
<SEQ ID NO. 1264;RNA;Artificial Sequence> ugcccuccugacgggacuc
<SEQ ID NO. 1265;RNA;Artificial Sequence> cacgccuggcacccacuac
<SEQ ID NO. 1266;RNA;Artificial Sequence> ccagcuggaugugcagcuc
<SEQ ID NO. 1267;RNA;Artificial Sequence> cuaccacugcacccuccug
<SEQ ID NO. 1268;RNA;Artificial Sequence> gggcccggccucgcccccu
<SEQ ID NO. 1269;RNA;Artificial Sequence> ugcacacgugcuucugccc
<SEQ ID NO. 1270;RNA;Artificial Sequence> ccccagugggccuccagcc
<SEQ ID NO. 1271;RNA;Artificial Sequence> cccccgacaccuccacgcc
<SEQ ID NO. 1272;RNA;Artificial Sequence> ccaggcccucucagacucc
<SEQ ID NO. 1273;RNA;Artificial Sequence> cgagauccagcugacaugg
<SEQ ID NO. 1274;RNA;Artificial Sequence> gaagcacccggaggcucug
<SEQ ID NO. 1275;RNA;Artificial Sequence> gccugggccaauauccaag
<SEQ ID NO. 1276;RNA;Artificial Sequence> guacguuguggaggugcag
<SEQ ID NO. 1277;RNA;Artificial Sequence> gguggcugggggugcagga
<SEQ ID NO. 1278;RNA;Artificial Sequence> agacccacuguggauagac
<SEQ ID NO. 1279;RNA;Artificial Sequence> cguggacaggccugaggag
<SEQ ID NO. 1280;RNA;Artificial Sequence> gacaagcaccaucauccgu
<SEQ ID NO. 1281;RNA;Artificial Sequence> uggccucaacgccagcacg
<SEQ ID NO. 1282;RNA;Artificial Sequence> gcgcuaccucuuccgcaug
<SEQ ID NO. 1283;RNA;Artificial Sequence> gcgggccagcauucagggg
<SEQ ID NO. I284;RNA;Artificial Sequence> gcucggggacuggagcaac
<SEQ ID NO. 1285;RNA;Artificial Sequence> cacaguagaagaguccacc
<SEQ ID NO. 1286;RNA;Artificial Sequence> ccugggcaacgggcugcag
<SEQ ID NO. 1287;RNA;Artificial Sequence> ggcugagggcccaguccaa
<SEQ ID NO. 1288;RNA;Artificial Sequence> agagagccgggcagcugaa
<SEQ ID NO. 1289;RNA;Artificial Sequence> agagggccuggaucagcag
<SEQ ID NO. 1290;RNA;Artificial Sequence> gcugauccuggcgguggug
<SEQ ID NO. 1291;RNA;Artificial Sequence> gggcuccgugucugccacc
<SEQ ID NO. 1292;RNA;Artificial Sequence> cugccucaccauccuggcc
<SEQ ID NO. 1293;RNA;Artificial Sequence> cgcccuuuuaacccuggug
<SEQ ID NO. 1294;RNA;Artificial Sequence> gugcauccgcagaagcugc
<SEQ ID NO. 1295;RNA;Artificial Sequence> ccugcaucggagacgcacc
<SEQ ID NO. 1296;RNA;Artificial Sequence> cuucaccuaccagucaggc
<SEQ ID NO. 1297;RNA;Artificial Sequence> cucgggcgaggagaccauc
<SEQ ID NO. 1298;RNA;Artificial Sequence> ccugcaguucagcucaggg
<SEQ ID NO. 1299;RNA;Artificial Sequence> gaccuugacacuuacccgg
<SEQ ID NO. 1300;RNA;Artificial Sequence> gcggccaaaacugcagccc
<SEQ ID NO. 1301;RNA;Artificial Sequence> cgagccccugagcuaccca
<SEQ ID NO. 1302;RNA;Artificial Sequence> agugcuagagugggaggac
<SEQ ID NO. 1303;RNA;Artificial Sequence> caucaccuuugaggaccuc
<SEQ ID NO. 1304;RNA;Artificial Sequence> caucggggaggggaacuuc
<SEQ ID NO. 1305;RNA;Artificial Sequence> cggccaggucauccgggcc
<SEQ ID NO. 1306;RNA;Artificial Sequence> caugaucaagaaggacggg
<SEQ ID NO. 1307;RNA;Artificial Sequence> gcugaagaugaacgcagcc
<SEQ ID NO. 1308;RNA;Artificial Sequence> caucaaaaugcugaaagag
<SEQ ID NO. 1309;RNA;Artificial Sequence> guaugccucugaaaaugac
741-3644

CA 02677068 2009-09-01
<SEQ ID NO. 1310;RNA;Artificial Sequence> ccaucgugacuuugcggga
<SEQ ID NO. 1311;RNA;Artificial Sequence> agaacuggaaguucugugc
<SEQ ID NO. 1312;RNA;Artificial Sequence> caaauuggggcaucacccc
<SEQ ID NO. 1313;RNA;Artificial Sequence> caacaucaucaaccuccug
<SEQ ID NO. 1314;RNA;Artificial Sequence> gggggccuguaagaaccga
<SEQ ID NO. 1315;RNA;Artificial Sequence> agguuacuuguauaucgcu
<SEQ ID NO. 1316;RNA;Artificial Sequence> uauugaauaugcccccuac
<SEQ ID NO. 1317;RNA;Artificial Sequence> cgggaaccugcuagauuuu
<SEQ ID NO. 1318;RNA;Artificial Sequence> ucugcggaaaagccggguc
<SEQ ID NO. 1319;RNA;Artificial Sequence> ccuagagacugacccagcu
<SEQ ID NO. 1320;RNA;Artificial Sequence> uuuugcucgagagcauggg
<SEQ ID NO. 1321;RNA;Artificial Sequence> gacagccucuacccuuagc
<SEQ ID NO. 1322;RNA;Artificial Sequence> cucccggcagcugcugegu
<SEQ ID NO. 1323;RNA;Artificial Sequence> uuucgccagugaugcggcc
<SEQ ID NO. 1324;RNA;Artificial Sequence> caauggcaugcaguaccug
<SEQ ID NO. 1325;RNA;Artificial Sequence> gagugagaagcaguucauc
<SEQ ID NO. 1326;RNA;Artificial Sequence> ccacagggaccuggcugec
<SEQ ID NO. 1327;RNA;Artificial Sequence> ccggaaugugcuggucgga
<SEQ ID NO. 1328;RNA;Artificial Sequence> agagaaccuagccuccaag
<SEQ ID NO. 1329;RNA;Artificial Sequence> gauugcagacuucggccuu
<SEQ ID NO. 1330;RNA;Artificial Sequence> uucucggggagaggagguu
<SEQ ID NO. 1331;RNA;Artificial Sequence> uuaugugaagaagacgaug
<SEQ ID NO. 1332;RNA;Artificial Sequence> ggggcgucucccugugcgc
<SEQ ID NO. 1333;RNA;Artificial Sequence> cuggauggccauugagucc
<SEQ ID NO. 1334;RNA;Artificial Sequence> ccugaacuacagugucuau
<SEQ ID NO. 1335;RNA;Artificial Sequence> uaccaccaagagugauguc
<SEQ ID NO. 1336;RNA;Artificial Sequence> cugguccuuuggaguccuu
<SEQ ID NO. 1337;RNA;Artificial Sequence> ucuuugggagauagugagc
<SEQ ID NO. 1338;RNA;Artificial Sequence> ccuuggagguacacccuac
<SEQ ID NO. 1339;RNA;Artificial Sequence> cuguggcaugaccugugcc
<SEQ ID NO. I340;RNA;Artificial Sequence> cgagcucuaugaaaagcug
<SEQ ID NO. 1341;RNA;Artificial Sequence> gccccagggcuaccgcaug
<SEQ ID NO. 1342;RNA;Artificial Sequence> ggagcagccucgaaacugu
<SEQ ID NO. 1343;RNA;Artificial Sequence> ugacgaugaaguguacgag
<SEQ ID NO. 1344;RNA;Artificial Sequence> gcugaugcgucagugcugg
<SEQ ID NO. 1345;RNA;Artificial Sequence> gcgggacegucccuaugag
<SEQ ID NO. 1346;RNA;Artificial Sequence> gcgaccccccuuugcccag
<SEQ ID NO. 1347;RNA;Artificial Sequence> gauugcgcuacagcuaggc
<SEQ ID NO. 1348;RNA;Artificial Sequence> ccgcaugcuggaagccagg
<SEQ ID NO. 1349;RNA;Artificial Sequence> gaaggccuaugugaacaug
<SEQ ID NO. 1350;RNA;Artificial Sequence> gucgcuguuugagaacuuc
<SEQ ID NO. 1351;RNA;Artificial Sequence> cacuuacgcgggcauugau
<SEQ ID NO. 1352;RNA;Artificial Sequence> ugccacagcugaggaggcc
<SEQ ID NO. 1353;RNA;Artificial Sequence> cugagcugccauccagcca
<SEQ ID NO. 1354;RNA;Artificial Sequence> agaacguggcucugcuggc
<SEQ ID NO. 1355;RNA;Artificial Sequence> ccggagcaaacucugcugu
<SEQ ID NO. 1356;RNA;Artificial Sequence> ucuaaccugugaccagucu
<SEQ ID NO. 1357;RNA;Artificial Sequence> ugacccuuacagccucuga
<SEQ ID NO. 1358;RNA;Artificial Sequence> acuuaagcugccucaagga
<SEQ ID NO. 1359;RNA;Artificial Sequence> aauuuuuuuaacuuaaggg
<SEQ ID NO. 1360;RNA;Artificial Sequence> gagaaaaaaagggaucugg
<SEQ ID NO. 1361;RNA;Artificial Sequence> gggauggggugggcuuagg
<SEQ ID NO. 1362;RNA;Artificial Sequence> gggaacuggguucccaugc
<SEQ ID NO. 1363;RNA;Artificial Sequence> cuuuguaggugucucauag
<SEQ ID NO. I364;RNA;Artificial Sequence> gcuauccugggcauccuuc
<SEQ ID NO. 1365;RNA;Artificial Sequence> cuuucuaguucagcugccc
<SEQ ID NO. 1366;RNA;Artificial Sequence> ccacagguguguuucccau
<SEQ ID NO. 1367;RNA;Artificial Sequence> ucccacugcucccccaaca
<SEQ ID NO. 1368;RNA;Artificial Sequence> acaaacccccacuccagcu
<SEQ ID NO. 1369;RNA;Artificial Sequence> uccuucgcuuaagccagca
<SEQ ID NO. I370;RNA;Artificial Sequence> acucacaccacuaacaugc
<SEQ ID NO. 1371;RNA;Artificial Sequence> cccuguucagcuacuccca
<SEQ ID NO. 1372;RNA;Artificial Sequence> acucccggccugucauuca
<SEQ ID NO. 1373;RNA;Artificial Sequence> agaaaaaaauaaauguucu
<SEQ ID NO. 1374;RNA;Artificial Sequence> uaauaagcuccaaaaaaaa
<SEQ ID NO. 1375;RNA;Artificial Sequence> cacaggcugagcagucaggcccaca
<SEQ ID NO. 1376;RNA;Artificial Sequence> agcaucugaccccaggcccagcucg
<SEQ ID NO. 1377;RNA;Artificial Sequence> guccuggcuggccugggucggccuc
<SEQ ID NO. I378;RNA;Artificial Sequence> cuggaguauggucuggcgggugccc
<SEQ ID NO. 1379;RNA;Artificial Sequence> cccuuucuugcuccccauccucuuc
<SEQ ID NO. 1380;RNA;Artificial Sequence> cuuggcuucucaugugggcgcggcg
<SEQ ID NO. 1381;RNA;Artificial Sequence> gguggaccugacgcugcuggccaac
<SEQ ID NO. 1382;RNA;Artificial Sequence> ccugcggcucacggacceccagcgc
741-3645

CA 02677068 2009-09-01
<SEQ ID NO. 1383;RNA;Artificial Sequence> cuucuuccugacuugcgugucuggg
<SEQ ID NO. 1384;RNA;Artificial Sequence> ggaggccggggcggggaggggcucg
<SEQ ID NO. 1385;RNA;Artificial Sequence> ggacgccuggggcccgccccugcug
<SEQ ID NO. 1386;RNA;Artificial Sequence> gcuggagaaggacgaccguaucgug
<SEQ ID NO. 1387;RNA;Artificial Sequence> gcgcaccccgcccgggccaccccug
<SEQ ID NO. I388;RNA;Artificial Sequence> gcgccuggcgcgcaacgguucgcac
<SEQ ID NO. 1389;RNA;Artificial Sequence> ccaggucacgcuucgcggcuucucc
<SEQ ID NO. 1390;RNA;Artificial Sequence> caagcccucggaccucgugggcguc
<SEQ ID NO. 1391;RNA;Artificial Sequence> cuucuccugcgugggcggugcuggg
<SEQ ID NO. 1392;RNA;Artificial Sequence> ggcgcggcgcacgcgcgucaucuac
<SEQ ID NO. 1393;RNA;Artificial Sequence> cgugcacaacagcccuggagcccac
<SEQ ID NO. 1394;RNA;Artificial Sequence> ccugcuuccagacaaggucacacac
<SEQ ID NO. 1395;RNA;Artificial Sequence> cacugugaacaaaggugacaccgcu
<SEQ ID NO. 1396;RNA;Artificial Sequence> uguacuuucugcacgugugcacaag
<SEQ ID NO. 1397;RNA;Artificial Sequence> ggagaagcagacagacgugaucugg
<SEQ ID NO. 1398;RNA;Artificial Sequence> gaagagcaacggauccuacuucuac
<SEQ ID NO. 1399;RNA;Artificial Sequence> cacccuggacuggcaugaagcccag
<SEQ ID NO. 1400;RNA;Artificial Sequence> ggaugggcgguuccugcugcagcuc
<SEQ ID NO. 1401;RNA;Artificial Sequence> cccaaaugugcagccaccaucgagc
<SEQ ID NO. I402;RNA;Artificial Sequence> cggcaucuacagugccacuuaccug
<SEQ ID NO. 1403;RNA;Artificial Sequence> ggaagccagcccccugggcagcgcc
<SEQ ID NO. 1404;RNA;Artificial Sequence> cuucuuucggcucaucgugcggggu
<SEQ ID NO. 1405;RNA;Artificial Sequence> uuguggggcugggcgcugggggcca
<SEQ ID NO. 1406;RNA;Artificial Sequence> aggcuguaccaaggagugcccaggu
<SEQ ID NO. 1407;RNA;Artificial Sequence> uugccuacauggaggugucugccac
<SEQ ID NO. 1408;RNA;Artificial Sequence> cgaccaugacggcgaauguguaugc
<SEQ ID NO. 1409;RNA;Artificial Sequence> ccccccuggcuucacuggcacccgc
<SEQ ID NO. 1410;RNA;Artificial Sequence> cugugaacaggccugcagagagggc
<SEQ ID NO. 1411;RNA;Artificial Sequence> ccguuuugggcagagcugccaggag
<SEQ ID NO. 1412;RNA;Artificial Sequence> gcagugcccaggcauaucaggcugc
<SEQ ID NO. 1413;RNA;Artificial Sequence> ccggggccucaccuucugccuccca
<SEQ ID NO. 1414;RNA;Artificial Sequence> agaccccuauggcugcucuugugga
<SEQ ID NO. 1415;RNA;Artificial Sequence> aucuggcuggagaggaagccagugc
<SEQ ID NO. 1416;RNA;Artificial Sequence> ccaagaagcuugugccccuggucau
<SEQ ID NO. 1417;RNA;Artificial Sequence> uuuuggggcugauugccgacuccag
<SEQ ID NO. 1418;RNA;Artificial Sequence> gugccagugucagaaugguggcacu
<SEQ ID NO. 1419;RNA;Artificial Sequence> uugugaccgguucagugguuguguc
<SEQ ID NO. 1420;RNA;Artificial Sequence> cugccccucuggguggcauggagug
<SEQ ID NO. 1421;RNA;Artificial Sequence> gcacugugagaagucagaccggauc
<SEQ ID NO. 1422;RNA;Artificial Sequence> cccccagauccucaacauggccuca
<SEQ ID NO. 1423;RNA;Artificial Sequence> agaacuggaguucaacuuagagacg
<SEQ ID NO. I424;RNA;Artificial Sequence> gaugccccggaucaacugugcagcu
<SEQ ID NO. 1425;RNA;Artificial Sequence> ugcagggaaccccuuccccgugcgg
<SEQ ID NO. 1426;RNA;Artificial Sequence> gggcagcauagagcuacgcaagcca
<SEQ ID NO. 1427;RNA;Artificial Sequence> agacggcacugugcuccuguccacc
<SEQ ID NO. 1428;RNA;Artificial Sequence> caaggccauuguggagccagagaag
<SEQ ID NO. 1429;RNA;Artificial Sequence> gaccacagcugaguucgaggugccc
<SEQ ID NO. 1430;RNA;Artificial Sequence> ccgcuugguucuugcggacaguggg
<SEQ ID NO. 1431;RNA;Artificial Sequence> guucugggagugccguguguccaca
<SEQ ID NO. 1432;RNA;Artificial Sequence> aucuggcggccaagacagccggcgc
<SEQ ID NO. 1433;RNA;Artificial Sequence> cuucaaggucaaugugaaagugccc
<SEQ ID NO. 1434;RNA;Artificial Sequence> ccccgugccccuggcugcaccucgg
<SEQ ID NO. 1435;RNA;Artificial Sequence> gcuccugaccaagcagagccgccag
<SEQ ID NO. 1436;RNA;Artificial Sequence> gcuuguggucuccccgcuggucucg
<SEQ ID NO. 1437;RNA;Artificial Sequence> guucucuggggauggacccaucucc
<SEQ ID NO. 1438;RNA;Artificial Sequence> cacuguccgccugcacuaccggccc
<SEQ ID NO. 1439;RNA;Artificial Sequence> ccaggacaguaccauggacuggucg
<SEQ ID NO. 1440;RNA;Artificial Sequence> gaccauugugguggaccccagugag
<SEQ ID NO. 1441;RNA;Artificial Sequence> gaacgugacguuaaugaaccugagg
<SEQ ID NO. 1442;RNA;Artificial Sequence> gccaaagacaggauacaguguucgu
<SEQ ID NO. 1443;RNA;Artificial Sequence> ugugcagcugagccggccaggggaa
<SEQ ID NO. 1444;RNA;Artificial Sequence> aggaggagagggggccugggggccu
<SEQ ID NO. 1445;RNA;Artificial Sequence> ucccacccucaugaccacagacugu
<SEQ ID NO. 1446;RNA;Artificial Sequence> uccugagccuuuguugcagccgugg
<SEQ ID NO. 1447;RNA;Artificial Sequence> guuggagggcuggcauguggaaggc
<SEQ ID NO. 1448;RNA;Artificial Sequence> cacugaccggcugcgagugagcugg
<SEQ ID NO. 1449;RNA;Artificial Sequence> guccuugcccuuggugcccgggcca
<SEQ ID NO. 1450;RNA;Artificial Sequence> acuggugggcgacgguuuccugcug
<SEQ ID NO. 1451;RNA;Artificial Sequence> gcgccugugggacgggacacggggg
<SEQ ID NO. 1452;RNA;Artificial Sequence> gcaggagcggcgggagaacgucuca
<SEQ ID NO. 1453;RNA;Artificial Sequence> auccccccaggcccgcacugcccuc
<SEQ ID NO. 1454;RNA;Artificial Sequence> ccugacgggacucacgccuggcacc
<SEQ ID NO. 1455;RNA;Artificial Sequence> ccacuaccagcuggaugugcagcuc
741-3646

CA 02677068 2009-09-01
<SEQ ID NO. 1456;RNA;Artificial Sequence> cuaccacugcacccuccugggcccg
<SEQ ID NO. 1457;RNA;Artificial Sequence> ggccucgcccccugcacacgugcuu
<SEQ ID NO. 1458;RNA;Artificial Sequence> ucugccccccagugggccuccagcc
<SEQ ID NO. 1459;RNA;Artificial Sequence> cccccgacaccuccacgcccaggcc
<SEQ ID NO. 1460;RNA;Artificial Sequence> ccucucagacuccgagauccagcug
<SEQ ID NO. 1461;RNA;Artificial Sequence> gacauggaagcacccggaggcucug
<SEQ ID NO. 1462;RNA;Artificial Sequence> gccugggccaauauccaaguacguu
<SEQ ID NO. 1463;RNA;Artificial Sequence> uguggaggugcagguggcugggggu
<SEQ ID NO. 1464;RNA;Artificial Sequence> ugcaggagacccacuguggauagac
<SEQ ID NO. 1465;RNA;Artificial Sequence> cguggacaggccugaggagacaagc
<SEQ ID NO. 1466;RNA;Artificial Sequence> caccaucauccguggccucaacgcc
<SEQ ID NO. 1467;RNA;Artificial Sequence> cagcacgcgcuaccucuuccgcaug
<SEQ ID NO. 1468;RNA;Artificial Sequence> gcgggccagcauucaggggcucggg
<SEQ ID NO. 1469;RNA;Artificial Sequence> ggacuggagcaacacaguagaagag
<SEQ ID NO. 1470;RNA;Artificial Sequence> guccacccugggcaacgggcugcag
<SEQ ID NO. 1471;RNA;Artificial Sequence> ggcugagggcccaguccaagagagc
<SEQ ID NO. 1472;RNA;Artificial Sequence> ccgggcagcugaagagggccuggau
<SEQ ID NO. 1473;RNA;Artificial Sequence> ucagcagcugauccuggcgguggug
<SEQ ID NO. 1474;RNA;Artificial Sequence> gggcuccgugucugccaccugccuc
<SEQ ID NO. 1475;RNA;Artificial Sequence> caccauccuggccgcccuuuuaacc
<SEQ ID NO. 1476;RNA;Artificial Sequence> ccuggugugcauccgcagaagcugc
<SEQ ID NO. 1477;RNA;Artificial Sequence> ccugcaucggagacgcaccuucacc
<SEQ ID NO. 1478;RNA;Artificial Sequence> cuaccagucaggcucgggcgaggag
<SEQ ID NO. 1479;RNA;Artificial Sequence> gaccauccugcaguucagcucaggg
<SEQ ID NO. 1480;RNA;Artificial Sequence> gaccuugacacuuacccggcggcca
<SEQ ID NO. 1481;RNA;Artificial Sequence> aaaacugcagcccgagccccugagc
<SEQ ID NO. 1482;RNA;Artificial Sequence> cuacccagugcuagagugggaggac
<SEQ ID NO. 1483;RNA;Artificial Sequence> caucaccuuugaggaccucaucggg
<SEQ ID NO. 1484;RNA;Artificial Sequence> ggaggggaacuucggccaggucauc
<SEQ ID NO. 1485;RNA;Artificial Sequence> ccgggccaugaucaagaaggacggg
<SEQ ID NO. 1486;RNA;Artificial Sequence> gcugaagaugaacgcagccaucaaa
<SEQ ID NO. 1487;RNA;Artificial Sequence> aaugcugaaagaguaugccucugaa
<SEQ ID NO. 1488;RNA;Artificial Sequence> aaaugaccaucgugacuuugcggga
<SEQ ID NO. 1489;RNA;Artificial Sequence> agaacuggaaguucugugcaaauug
<SEQ ID NO. 1490;RNA;Artificial Sequence> ggggcaucaccccaacaucaucaac
<SEQ ID NO. 1491;RNA;Artificial Sequence> ccuccugggggccuguaagaaccga
<SEQ ID NO. 1492;RNA;Artificial Sequence> agguuacuuguauaucgcuauugaa
<SEQ ID NO. 1493;RNA;Artificial Sequence> auaugcccccuacgggaaccugcua
<SEQ ID NO. 1494;RNA;Artificial Sequence> agauuuucugcggaaaagccggguc
<SEQ ID NO. 1495;RNA;Artificial Sequence> ccuagagacugacccagcuuuugcu
<SEQ ID NO. 1496;RNA;Artificial Sequence> ucgagagcaugggacagccucuacc
<SEQ ID NO. 1497;RNA;Artificial Sequence> ccuuagcucccggcagcugcugcgu
<SEQ ID NO. 1498;RNA;Artificial Sequence> uuucgccagugaugcggccaauggc
<SEQ ID NO. 1499;RNA;Artificial Sequence> caugcaguaccugagugagaagcag
<SEQ ID NO. 1500;RNA;Artificial Sequence> guucauccacagggaccuggcugcc
<SEQ ID NO. 1501;RNA;Artificial Sequence> ccggaaugugcuggucggagagaac
<SEQ ID NO. 1502;RNA;Artificial Sequence> ccuagccuccaagauugcagacuuc
<SEQ ID NO. 1503;RNA;Artificial Sequence> cggccuuucucggggagaggagguu
<SEQ ID NO. 1504;RNA;Artificial Sequence> uuaugugaagaagacgauggggcgu
<SEQ ID NO. 1505;RNA;Artificial Sequence> ucucccugugcgcuggauggccauu
<SEQ ID NO. 1506;RNA;Artificial Sequence> ugagucccugaacuacagugucuau
<SEQ ID NO. 1507;RNA;Artificial Sequence> uaccaccaagagugaugucuggucc
<SEQ ID NO. 1508;RNA;Artificial Sequence> cuuuggaguccuucuuugggagaua
<SEQ ID NO. 1509;RNA;Artificial Sequence> agugagccuuggagguacacccuac
<SEQ ID NO. 1510;RNA;Artificial Sequence> cuguggcaugaccugugccgagcuc
<SEQ ID NO. 1511;RNA;Artificial Sequence> cuaugaaaagcugccccagggcuac
<SEQ ID NO. 1512;RNA;Artificial Sequence> ccgcauggagcagccucgaaacugu
<SEQ ID NO. 1513;RNA;Artificial Sequence> ugacgaugaaguguacgagcugaug
<SEQ ID NO. 1514;RNA;Artificial Sequence> gcgucagugcuggcgggaccguccc
<SEQ ID NO. 1515;RNA;Artificial Sequence> cuaugagcgaccccccuuugcccag
<SEQ ID NO. 1516;RNA;Artificial Sequence> gauugcgcuacagcuaggccgcaug
<SEQ ID NO. 1517;RNA;Artificial Sequence> gcuggaagccaggaaggccuaugug
<SEQ ID NO. 1518;RNA;Artificial Sequence> gaacaugucgcuguuugagaacuuc
<SEQ ID NO. 1519;RNA;Artificial Sequence> cacuuacgcgggcauugaugccaca
<SEQ ID NO. 1520;RNA;Artificial Sequence> agcugaggaggccugagcugccauc
<SEQ ID NO. 1521;RNA;Artificial Sequence> ccagccagaacguggcucugcuggc
<SEQ ID NO. 1522;RNA;Artificial Sequence> ccggagcaaacucugcugucuaacc
<SEQ ID NO. 1523;RNA;Artificial Sequence> cugugaccagucugacccuuacagc
<SEQ ID NO. I524;RNA;Artificial Sequence> ccucugacuuaagcugccucaagga
<SEQ ID NO. 1525;RNA;Artificial Sequence> aauuuuuuuaacuuaagggagaaaa
<SEQ ID NO. 1526;RNA;Artificial Sequence> aaaagggaucuggggaugggguggg
<SEQ ID NO. 1527;RNA;Artificial Sequence> gcuuaggggaacuggguucccaugc
<SEQ ID NO. 1528;RNA;Artificial Sequence> cuuuguaggugucucauagcuaucc
741-3647

CA 02677068 2009-09-01
<SEQ ID NO. 1529;RNA;Artificial Sequence> cugggcauccuucuuucuaguucag
<SEQ ID NO. 1530;RNA;Artificial Sequence> gcugccccacagguguguuucccau
<SEQ ID NO. 1531;RNA;Artificial Sequence> ucccacugcucccccaacacaaacc
<SEQ ID NO. 1532;RNA;Artificial Sequence> ccccacuccagcuccuucgcuuaag
<SEQ ID NO. 1533;RNA;Artificial Sequence> gccagcacucacaccacuaacaugc
<SEQ ID NO. 1534;RNA;Artificial Sequence> cccuguucagcuacucccacucccg
<SEQ ID NO. 1535;RNA;Artificial Sequence> ggccugucauucagaaaaaaauaaa
<SEQ ID NO. 1536;RNA;Artificial Sequence> auguucuaauaagcuccaaaaaaaa
<SEQ ID NO. 1537;RNA;Homo sapiens>
UGAAUUGCGAGAUGGAUAGGGCUUGAGUGCCCCCAGCCCUGCUGAUACCAAAUGCCUUUAAGAUACAGCC
UUUCCCAUCCUAAUCUACAAAGGAAACAGGAAAAAGGAACUUAAAACUCCCUGUGCUCAGACAGAAAUGAGACUGU
UACAGCCUGCUUCUGUGCUGUUCCUUCUUGCCUCUAACUUGUAAACAAGACGUAGUAGGACGAUGCUAAUGGAAAG
UCACAAACCGCUGGGUUUUUGAAAGGAUCCUUGGGACCUCAUGCACAUUUGUGGAAACUGGAUGGAGAGAUUUGGG
GAAGCAUGGACUCUUUAGCCAGCUUAGUUCUCUGUGGAGUCAGCUUGCUCCUUUCUGGAACUGUGGAAGGUGCCAU
GGACUUGAUCUUGAUCAAUUCCCUACCUCUUGUAUCUGAUGCUGAAACAUCUCUCACCUGCAUUGCCUCUGGGUGGC
GCCCCCAUGAGCCCAUCACCAUAGGAAGGGACUUUGAAGCCUUAAUGAACCAGCACCAGGAUCCGCUGGAAGUUACU
CAAGAUGUGACCAGAGAAUGGGCUAAAAAAGUUGUUUGGAAGAGAGAAAAGGCUAGUAAGAUCAAUGGUGCUUAUU
UCUGUGAAGGGCGAGUUCGAGGAGAGGCAAUCAGGAUACGAACCAUGAAGAUGCGUCAACAAGCUUCCUUCCUACCA
GCUACUUUAACUAUGACUGUGGACAAGGGAGAUAACGUGAACAUAUCUUUCAAAAAGGUAUUGAUUAAAGAAGAAG
AUGCAGUGAUUUACAAAAAUGGUUCCUUCAUCCAUUCAGUGCCCCGGCAUGAAGUACCUGAUAUUCUAGAAGUACAC
CUGCCUCAUGCUCAGCCCCAGGAUGCUGGAGUGUACUCGGCCAGGUAUAUAGGAGGAAACCUCUUCACCUCGGCCUU
CACCAGGCUGAUAGUCCGGAGAUGUGAAGCCCAGAAGUGGGGACCUGAAUGCAACCAUCUCUGUACUGCUUGUAUGA
ACAAUGGUGUCUGCCAUGAAGAUACUGGAGAAUGCAUUUGCCCUCCUGGGUUUAUGGGAAGGACGUGUGAGAAGGC
UUGUGAACUGCACACGUUUGGCAGAACUUGUAAAGAAAGGUGCAGUGGACAAGAGGGAUGCAAGUCUUAUGUGUUC
UGUCUCCCUGACCCCUAUGGGUGUUCCUGUGCCACAGGCUGGAAGGGUCUGCAGUGCAAUGAAGCAUGCCACCCUGG
UUUUUACGGGCCAGAUUGUAAGCUUAGGUGCAGCUGCAACAAUGGGGAGAUGUGUGAUCGCUUCCAAGGAUGUCUC
UGCUCUCCAGGAUGGCAGGGGCUCCAGUGUGAGAGAGAAGGCAUACCGAGGAUGACCCCAAAGAUAGUGGAUUUGC
CAGAUCAUAUAGAAGUAAACAGUGGUAAAUUUAAUCCCAUUUGCAAAGCUUCUGGCUGGCCGCUACCUACUAAUGA
AGAAAUGACCCUGGUGAAGCCGGAUGGGACAGUGCUCCAUCCAAAAGACUUUAACCAUACGGAUCAUUUCUCAGUAG
CCAUAUUCACCAUCCACCGGAUCCUCCCCCCUGACUCAGGAGUUUGGGUCUGCAGUGUGAACACAGUGGCUGGGAUG
GUGGAAAAGCCCUUCAACAUUUCUGUUAAAGUUCUUCCAAAGCCCCUGAAUGCCCCAAACGUGAUUGACACUGGACA
UAACUUUGCUGUCAUCAACAUCAGCUCUGAGCCUUACUUUGGGGAUGGACCAAUCAAAUCCAAGAAGCUUCUAUACA
AACCCGUUAAUCACUAUGAGGCUUGGCAACAUAUUCAAGUGACAAAUGAGAUUGUUACACUCAACUAUUUGGAACC
UCGGACAGAAUAUGAACUCUGUGUGCAACUGGUCCGUCGUGGAGAGGGUGGGGAAGGGCAUCCUGGACCUGUGAGA
CGCUUCACAACAGCUUCUAUCGGACUCCCUCCUCCAAGAGGUCUAAAUCUCCUGCCUAAAAGUCAGACCACUCUAAA
UUUGACCUGGCAACCAAUAUUUCCAAGCUCGGAAGAUGACUUUUAUGUUGAAGUGGAGAGAAGGUCUGUGCAAAAA
AGUGAUCAGCAGAAUAUUAAAGUUCCAGGCAACUUGACUUCGGUGCUACUUAACAACUUACAUCCCAGGGAGCAGU
ACGUGGUCCGAGCUAGAGUCAACACCAAGGCCCAGGGGGAAUGGAGUGAAGAUCUCACUGCUUGGACCCUUAGUGAC
AUUCUUCCUCCUCAACCAGAAAACAUCAAGAUUUCCAACAUUACACACUCCUCAGCUGUGAUUUCUUGGACAAUAUU
GGAUGGCUAUUCUAUUUCUUCUAUUACUAUCCGUUACAAGGUUCAAGGCAAGAAUGAAGACCAGCACGUUGAUGUG
AAGAUAAAGAAUGCCACCAUCACUCAGUAUCAGCUCAAGGGCCUAGAGCCUGAAACAGCAUACCAGGUGGACAUUUU
UGCAGAGAACAACAUAGGGUCAAGCAACCCAGCCUUUUCUCAUGAACUGGUGACCCUCCCAGAAUCUCAAGCACCAG
CGGACCUCGGAGGGGGGAAGAUGCUGCUUAUAGCCAUCCUUGGCUCUGCUGGAAUGACCUGCCUGACUGUGCUGUUG
GCCUUUCUGAUCAUAUUGCAAUUGAAGAGGGCAAAUGUGCAAAGGAGAAUGGCCCAAGCCUUCCAAAACGUGAGGG
AAGAACCAGCUGUGCAGUUCAACUCAGGGACUCUGGCCCUAAACAGGAAGGUCAAAAACAACCCAGAUCCUACAAUU
UAUCCAGUGCUUGACUGGAAUGACAUCAAAUUUCAAGAUGUGAUUGGGGAGGGCAAUUUUGGCCAAGUUCUUAAGG
CGCGCAUCAAGAAGGAUGGGUUACGGAUGGAUGCUGCCAUCAAAAGAAUGAAAGAAUAUGCCUCCAAAGAUGAUCA
CAGGGACUUUGCAGGAGAACUGGAAGUUCUUUGUAAACUUGGACACCAUCCAAACAUCAUCAAUCUCUUAGGAGCA
UGUGAACAUCGAGGCUACUUGUACCUGGCCAUUGAGUACGCGCCCCAUGGAAACCUUCUGGACUUCCUUCGCAAGAG
CCGUGUGCUGGAGACGGACCCAGCAUUUGCCAUUGCCAAUAGCACCGCGUCCACACUGUCCUCCCAGCAGCUCCUUC
ACUUCGCUGCCGACGUGGCCCGGGGCAUGGACUACUUGAGCCAAAAACAGUUUAUCCACAGGGAUCUGGCUGCCAGA
AACAUUUUAGUUGGUGAAAACUAUGUGGCAAAAAUAGCAGAUUUUGGAUUGUCCCGAGGUCAAGAGGUGUAUGUGA
AAAAGACAAUGGGAAGGCUCCCAGUGCGCUGGAUGGCCAUCGAGUCACUGAAUUACAGUGUGUACACAACCAACAGU
GAUGUAUGGUCCUAUGGUGUGUUACUAUGGGAGAUUGUUAGCUUAGGAGGCACACCCUACUGCGGGAUGACUUGUG
CAGAACUCUACGAGAAGCUGCCCCAGGGCUACAGACUGGAGAAGCCCCUGAACUGUGAUGAUGAGGUGUAUGAUCUA
AUGAGACAAUGCUGGCGGGAGAAGCCUUAUGAGAGGCCAUCAUUUGCCCAGAUAUUGGUGUCCUUAAACAGAAUGU
UAGAGGAGCGAAAGACCUACGUGAAUACCACGCUUUAUGAGAAGUUUACUUAUGCAGGAAUUGACUGUUCUGCUGA
AGAAGCGGCCUAGGACAGAACAUCUGUAUACCCUCUGUUUCCCUUUCACUGGCAUGGGAGACCCUUGACACCUGCUG
AGAAAACAUGCCUCUGCCAAAGGAUGUGAUAUAUAAGUGUACAUAUGUGCUGUACACCUGGGACCUUCACCACUGU
AGAUCCCAUGCAUGGAUCUAUGUAGUAUGCUCUGACUCUAAUAGGACUGUAUAUACUGUUUUAAGAAUGGGCUGAA
AUCAGAAUGCCUGUUUGUGGUUUCAUAUGCAAUAAUAUAUUUUUUUAAAAAUGUGGACUUCAUAGGAAGGCGUGAG
UACAAUUAGUAUAAUGCAUAACUCAUUGUUGUCCUAGAUAUUUUGAUAUUUACCUUUAUGUUGAAUGCUAUUAAAU
GUUUUCCUGUGUCAAAGUAAAAUAUUGUUAAUAAACCUAACAAUGACCCUGAUAGUACAGGUUAAGUGAGAGAACU
AUAUGAAUUCUAACAAGUCAUAGGUUAAUAUUUAAGACACUGAAAAAUCUAAGUGAUAUAAAUCAGAUUCUUCUCU
CUCAAUUUUAUCCCUCACCUGUAGCAGCCAGUCCCGUUUCAUUUAGUCAUGUGACCACUCUGUCUUGUGUUUCCACA
GCCUGCAAGUCAGUCCAGGAUGCUAACAUCUAAAAAUAGACUUAAAUCUCAUUGCUUACAAGCCUAAGAAUCUUUA
GAGAAGUAUACAUAAGUUUAGGAUAAAAUAAUGGGAUUUUCUUUUCUUUUCUCUGGUAAUAUUGACUUGUAUAUUU
UAAGAAAUAACAGAAAGCCUGGGUGACAUUUGGGAGACAUGUGACAUUUAUAUAUUGAAUUAAUAUCCCUACAUGU
AUUGCACAUUGUAAAAAGUUUUAGUUUUGAUGAGUUGUGAGUUUACCUUGUAUACUGUAGGCACACUUUGCACUGA
UAUAUCAUGAGUGAAUAAAUGUCUUGCCUACUCACGUCUCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1538;RNA;Artificial Sequence> ugaauugcgagauggauag
<SEQ ID NO. 1539;RNA;Artificial Sequence> gggcuugagugcccccagc
741-3648

CA 02677068 2009-09-01
<SEQ ID NO. I540;RNA;Artificial Sequence> cccugcugauaccaaaugc
<SEQ ID NO. 1541;RNA;Artificial Sequence> ccuuuaagauacagccuuu
<SEQ ID NO. 1542;RNA;Artificial Sequence> ucccauccuaaucuacaaa
<SEQ ID NO. 1543;RNA;Artificial Sequence> aggaaacaggaaaaaggaa
<SEQ ID NO. 1544;RNA;Artificial Sequence> acuuaaaacucccugugcu
<SEQ ID NO. 1545;RNA;Artificial Sequence> ucagacagaaaugagacug
<SEQ ID NO. 1546;RNA;Artificial Sequence> guuacagccugcuucugug
<SEQ ID NO. 1547;RNA;Artificial Sequence> gcuguuccuucuugccucu
<SEQ ID NO. 1548;RNA;Artificial Sequence> uaacuuguaaacaagacgu
<SEQ ID NO. 1549;RNA;Artificial Sequence> uaguaggacgaugcuaaug
<SEQ ID NO. 1550;RNA;Artificial Sequence> ggaaagucacaaaccgcug
<SEQ ID NO. 1551;RNA;Artificial Sequence> ggguuuuugaaaggauccu
<SEQ ID NO. 1552;RNA;Artificial Sequence> uugggaccucaugcacauu
<SEQ ID NO. 1553;RNA;Artificial Sequence> uuguggaaacuggauggag
<SEQ ID NO. 1554;RNA;Artificial Sequence> gagauuuggggaagcaugg
<SEQ ID NO. 1555;RNA;Artificial Sequence> gacucuuuagccagcuuag
<SEQ ID NO. 1556;RNA;Artificial Sequence> guucucuguggagucagcu
<SEQ ID NO. 1557;RNA;Artificial Sequence> uugcuccuuucuggaacug
<SEQ ID NO. 1558;RNA;Artificial Sequence> guggaaggugccauggacu
<SEQ ID NO. 1559;RNA;Artificial Sequence> uugaucuugaucaauuccc
<SEQ ID NO. 1560;RNA;Artificial Sequence> cuaccucuuguaucugaug
<SEQ ID NO. 1561;RNA;Artificial Sequence> gcugaaacaucucucaccu
<SEQ ID NO. 1562;RNA;Artificial Sequence> ugcauugccucuggguggc
<SEQ ID NO. 1563;RNA;Artificial Sequence> cgcccccaugagcccauca
<SEQ ID NO. 1564;RNA;Artificial Sequence> accauaggaagggacuuug
<SEQ ID NO. 1565;RNA;Artificial Sequence> gaagccuuaaugaaccagc
<SEQ ID NO. 1566;RNA;Artificial Sequence> caccaggauccgcuggaag
<SEQ ID NO. 1567;RNA;Artificial Sequence> guuacucaagaugugacca
<SEQ ID NO. 1568;RNA;Artificial Sequence> agagaaugggcuaaaaaag
<SEQ ID NO. 1569;RNA;Artificial Sequence> guuguuuggaagagagaaa
<SEQ ID NO. 1570;RNA;Artificial Sequence> aaggcuaguaagaucaaug
<SEQ ID NO. 1571;RNA;Artificial Sequence> ggugcuuauuucugugaag
<SEQ ID NO. 1572;RNA;Artificial Sequence> gggcgaguucgaggagagg
<SEQ ID NO. 1573;RNA;Artificial Sequence> gcaaucaggauacgaacca
<SEQ ID NO. 1574;RNA;Artificial Sequence> augaagaugcgucaacaag
<SEQ ID NO. 1575;RNA;Artificial Sequence> gcuuccuuccuaccagcua
<SEQ ID NO. 1576;RNA;Artificial Sequence> acuuuaacuaugacugugg
<SEQ ID NO. 1577;RNA;Artificial Sequence> gacaagggagauaacguga
<SEQ ID NO. 1578;RNA;Artificial Sequence> aacauaucuuucaaaaagg
<SEQ ID NO. 1579;RNA;Artificial Sequence> guauugauuaaagaagaag
<SEQ ID NO. 1580;RNA;Artificial Sequence> gaugcagugauuuacaaaa
<SEQ ID NO. 1581;RNA;Artificial Sequence> aaugguuccuucauccauu
<SEQ ID NO. 1582;RNA;Artificial Sequence> ucagugccccggcaugaag
<SEQ ID NO. 1583;RNA;Artificial Sequence> guaccugauauucuagaag
<SEQ ID NO. 1584;RNA;Artificial Sequence> guacaccugccucaugcuc
<SEQ ID NO. 1585;RNA;Artificial Sequence> cagccccaggaugcuggag
<SEQ ID NO. 1586;RNA;Artificial Sequence> guguacucggccagguaua
<SEQ ID NO. 1587;RNA;Artificial Sequence> auaggaggaaaccucuuca
<SEQ ID NO. 1588;RNA;Artificial Sequence> accucggccuucaccaggc
<SEQ ID NO. 1589;RNA;Artificial Sequence> cugauaguccggagaugug
<SEQ ID NO. 1590;RNA;Artificial Sequence> gaagcccagaaguggggac
<SEQ ID NO. 1591;RNA;Artificial Sequence> ccugaaugcaaccaucucu
<SEQ ID NO. 1592;RNA;Artificial Sequence> uguacugcuuguaugaaca
<SEQ ID NO. 1593;RNA;Artificial Sequence> aauggugucugccaugaag
<SEQ ID NO. 1594;RNA;Artificial Sequence> gauacuggagaaugcauuu
<SEQ ID NO. 1595;RNA;Artificial Sequence> ugcccuccuggguuuaugg
<SEQ ID NO. 1596;RNA;Artificial Sequence> ggaaggacgugugagaagg
<SEQ ID NO. 1597;RNA;Artificial Sequence> gcuugugaacugcacacgu
<SEQ ID NO. 1598;RNA;Artificial Sequence> uuuggcagaacuuguaaag
<SEQ ID NO. 1599;RNA;Artificial Sequence> gaaaggugcaguggacaag
<SEQ ID NO. 1600;RNA;Artificial Sequence> gagggaugcaagucuuaug
<SEQ ID NO. 1601;RNA;Artificial Sequence> guguucugucucccugacc
<SEQ ID NO. 1602;RNA;Artificial Sequence> cccuauggguguuccugug
<SEQ ID NO. 1603;RNA;Artifrcial Sequence> gccacaggcuggaaggguc
<SEQ ID NO. 1604;RNA;Artificial Sequence> cugcagugcaaugaagcau
<SEQ ID NO. 1605;RNA;Artificial Sequence> ugccacccugguuuuuacg
<SEQ ID NO. 1606;RNA;Artificial Sequence> gggccagauuguaagcuua
<SEQ ID NO. 1607;RNA;Artificial Sequence> aggugcagcugcaacaaug
<SEQ ID NO. 1608;RNA;Artificial Sequence> ggggagaugugugaucgcu
<SEQ ID NO. 1609;RNA;Artificial Sequence> uuccaaggaugucucugcu
<SEQ ID NO. 1610;RNA;Artifscial Sequence> ucuccaggauggcaggggc
<SEQ ID NO. 1611;RNA;Artificial Sequence> cuccagugugagagagaag
<SEQ ID NO. 1612;RNA;Artificial Sequence> ggcauaccgaggaugaccc
741-3649

CA 02677068 2009-09-01
<SEQ ID NO. 1613;RNA;Artificial Sequence> ccaaagauaguggauuugc
<SEQ ID NO. 1614;RNA;Artificial Sequence> ccagaucauauagaaguaa
<SEQ ID NO. 1615;RNA;Artificial Sequence> aacagugguaaauuuaauc
<SEQ ID NO. 1616;RNA;Artificial Sequence> cccauuugcaaagcuucug
<SEQ ID NO. 1617;RNA;Artificial Sequence> ggcuggccgcuaccuacua
<SEQ ID NO. 1618;RNA;Artificial Sequence> aaugaagaaaugacccugg
<SEQ ID NO. 1619;RNA;Artificial Sequence> gugaagccggaugggacag
<SEQ ID NO. 1620;RNA;Artificial Sequence> gugcuccauccaaaagacu
<SEQ ID NO. 1621;RNA;Artificial Sequence> uuuaaccauacggaucauu
<SEQ ID NO. 1622;RNA;Artificial Sequence> uucucaguagccauauuca
<SEQ ID NO. 1623;RNA;Artificial Sequence> accauccaccggauccucc
<SEQ ID NO. 1624;RNA;Artificial Sequence> cccccugacucaggaguuu
<SEQ ID NO. 1625;RNA;Artificial Sequence> ugggucugcagugugaaca
<SEQ ID NO. 1626;RNA;Artificial Sequence> acaguggcugggauggugg
<SEQ ID NO. 1627;RNA;Artificial Sequence> gaaaagcccuucaacauuu
<SEQ ID NO. 1628;RNA;Artificial Sequence> ucuguuaaaguucuuccaa
<SEQ ID NO. 1629;RNA;Artificial Sequence> aagccccugaaugccccaa
<SEQ ID NO. 1630;RNA;Artificial Sequence> aacgugauugacacuggac
<SEQ ID NO. 1631;RNA;Artificial Sequence> cauaacuuugcugucauca
<SEQ ID NO. 1632;RNA;Artificial Sequence> aacaucagcucugagccuu
<SEQ ID NO. 1633;RNA;Artificial Sequence> uacuuuggggauggaccaa
<SEQ ID NO. 1634;RNA;Artificial Sequence> aucaaauccaagaagcuuc
<SEQ ID NO. 1635;RNA;Artificial Sequence> cuauacaaacccguuaauc
<SEQ ID NO. I636;RNA;Artificial Sequence> cacuaugaggcuuggcaac
<SEQ ID NO. 1637;RNA;Artificial Sequence> cauauucaagugacaaaug
<SEQ ID NO. 1638;RNA;Artificial Sequence> gagauuguuacacucaacu
<SEQ ID NO. 1639;RNA;Artificial Sequence> uauuuggaaccucggacag
<SEQ ID NO. 1640;RNA;Artificial Sequence> gaauaugaacucugugugc
<SEQ ID NO. 1641;RNA;Artificial Sequence> caacugguccgucguggag
<SEQ ID NO. 1642;RNA;Artificial Sequence> gaggguggggaagggcauc
<SEQ ID NO. 1643;RNA;Artificial Sequence> ccuggaccugugagacgcu
<SEQ ID NO. 1644;RNA;Artificial Sequence> uucacaacagcuucuaucg
<SEQ ID NO. 1645;RNA;Artificial Sequence> ggacucccuccuccaagag
<SEQ ID NO. 1646;RNA;Artificial Sequence> ggucuaaaucuccugccua
<SEQ ID NO. 1647;RNA;Artificial Sequence> aaaagucagaccacucuaa
<SEQ ID NO. 1648;RNA;Artificial Sequence> aauuugaccuggcaaccaa
<SEQ ID NO. 1649;RNA;Artificial Sequence> auauuuccaagcucggaag
<SEQ ID NO. 1650;RNA;Artificial Sequence> gaugacuuuuauguugaag
<SEQ ID NO. 1651;RNA;Artificial Sequence> guggagagaaggucugugc
<SEQ ID NO. 1652;RNA;Artificial Sequence> caaaaaagugaucagcaga
<SEQ ID NO. 1653;RNA;Artificial Sequence> aauauuaaaguuccaggca
<SEQ ID NO. 1654;RNA;Artificial Sequence> aacuugacuucggugcuac
<SEQ ID NO. 1655;RNA;Artificial Sequence> cuuaacaacuuacauccca
<SEQ ID NO. 1656;RNA;Artificial Sequence> agggagcaguacguggucc
<SEQ ID NO. 1657;RNA;Artificial Sequence> cgagcuagagucaacacca
<SEQ ID NO. 1658;RNA;Artificial Sequence> aaggcccagggggaaugga
<SEQ ID NO. 1659;RNA;Artificial Sequence> agugaagaucucacugcuu
<SEQ ID NO. 1660;RNA;Artificial Sequence> uggacccuuagugacauuc
<SEQ ID NO. 1661;RNA;Artificial Sequence> cuuccuccucaaccagaaa
<SEQ ID NO. 1662;RNA;Artificial Sequence> aacaucaagauuuccaaca
<SEQ ID NO. 1663;RNA;Artificial Sequence> auuacacacuccucagcug
<SEQ ID NO. 1664;RNA;Artificial Sequence> gugauuucuuggacaauau
<SEQ ID NO. 1665;RNA;Artificial Sequence> uuggauggcuauucuauuu
<SEQ ID NO. 1666;RNA;Artificial Sequence> ucuucuauuacuauccguu
<SEQ ID NO. 1667;RNA;Artificial Sequence> uacaagguucaaggcaaga
<SEQ ID NO. 1668;RNA;Artificial Sequence> aaugaagaccagcacguug
<SEQ ID NO. 1669;RNA;Artificial Sequence> gaugugaagauaaagaaug
<SEQ ID NO. 1670;RNA;Artificial Sequence> gccaccaucacucaguauc
<SEQ ID NO. 1671;RNA;Artificial Sequence> cagcucaagggccuagagc
<SEQ ID NO. 1672;RNA;Artificial Sequence> ccugaaacagcauaccagg
<SEQ ID NO. 1673;RNA;Artificial Sequence> guggacauuuuugcagaga
<SEQ ID NO. 1674;RNA;Artificial Sequence> aacaacauagggucaagca
<SEQ ID NO. 1675;RNA;Artificial Sequence> aacccagccuuuucucaug
<SEQ ID NO. 1676;RNA;Artificial Sequence> gaacuggugacccucccag
<SEQ ID NO. 1677;RNA;Artificial Sequence> gaaucucaagcaccagcgg
<SEQ ID NO. 1678;RNA;Artificial Sequence> gaccucggaggggggaaga
<SEQ ID NO. 1679;RNA;Artificial Sequence> augcugcuuauagccaucc
<SEQ ID NO. 1680;RNA;Artificial Sequence> cuuggcucugcuggaauga
<SEQ ID NO. 1681;RNA;Artificial Sequence> accugccugacugugcugu
<SEQ ID NO. 1682;RNA;Artificial Sequence> uuggccuuucugaucauau
<SEQ ID NO. 1683;RNA;Artificial Sequence> uugcaauugaagagggcaa
<SEQ ID NO. 1684;RNA;Artificial Sequence> aaugugcaaaggagaaugg
<SEQ ID NO. 1685;RNA;Artificial Sequence> gcccaagccuuccaaaacg
741-3650

CA 02677068 2009-09-01
<SEQ ID NO. 1686;RNA;Artificial Sequence> gugagggaagaaccagcug
<SEQ ID NO. 1687;RNA;Artificial Sequence> gugcaguucaacucaggga
<SEQ ID NO. 1688;RNA;Artificial Sequence> acucuggcccuaaacagga
<SEQ ID NO. 1689;RNA;Artificial Sequence> aaggucaaaaacaacccag
<SEQ ID NO. 1690;RNA;Artificial Sequence> gauccuacaauuuauccag
<SEQ ID NO. 1691;RNA;Artificial Sequence> gugcuugacuggaaugaca
<SEQ ID NO. 1692;RNA;Artificial Sequence> aucaaauuucaagauguga
<SEQ ID NO. 1693;RNA;Artificial Sequence> auuggggagggcaauuuug
<SEQ ID NO. 1694;RNA;Artificial Sequence> ggccaaguucuuaaggcgc
<SEQ ID NO. 1695;RNA;Artificial Sequence> cgcaucaagaaggaugggu
<SEQ ID NO. 1696;RNA;Artificial Sequence> uuacggauggaugcugcca
<SEQ ID NO. 1697;RNA;Artificial Sequence> aucaaaagaaugaaagaau
<SEQ ID NO. 1698;RNA;Artificial Sequence> uaugccuccaaagaugauc
<SEQ ID NO. 1699;RNA;Artificial Sequence> cacagggacuuugcaggag
<SEQ ID NO. 1700;RNA;Artificial Sequence> gaacuggaaguucuuugua
<SEQ ID NO. 1701;RNA;Artificial Sequence> aaacuuggacaccauccaa
<SEQ ID NO. 1702;RNA;Artificial Sequence> aacaucaucaaucucuuag
<SEQ ID NO. 1703;RNA;Artificial Sequence> ggagcaugugaacaucgag
<SEQ ID NO. 1704;RNA;Artificial Sequence> ggcuacuuguaccuggcca
<SEQ ID NO. 1705;RNA;Artificial Sequence> auugaguacgcgccccaug
<SEQ ID NO. 1706;RNA;Artificial Sequence> ggaaaccuucuggacuucc
<SEQ ID NO. 1707;RNA;Artificial Sequence> cuucgcaagagccgugugc
<SEQ ID NO. 1708;RNA;Artificial Sequence> cuggagacggacccagcau
<SEQ ID NO. 1709;RNA;Artificial Sequence> uuugccauugccaauagca
<SEQ ID NO. 1710;RNA;Artificial Sequence> accgcguccacacuguccu
<SEQ ID NO. 1711;RNA;Artificial Sequence> ucccagcagcuccuucacu
<SEQ ID NO. 1712;RNA;Artificial Sequence> uucgcugccgacguggccc
<SEQ ID NO. 1713;RNA;Artificial Sequence> cggggcauggacuacuuga
<SEQ ID NO. 1714;RNA;Artificial Sequence> agccaaaaacaguuuaucc
<SEQ ID NO. 1715;RNA;Artificial Sequence> cacagggaucuggcugcca
<SEQ ID NO. 1716;RNA;Artificial Sequence> agaaacauuuuaguuggug
<SEQ ID NO. 1717;RNA;Artificial Sequence> gaaaacuauguggcaaaaa
<SEQ ID NO. 1718;RNA;Artificial Sequence> auagcagauuuuggauugu
<SEQ ID NO. 1719;RNA;Artificial Sequence> ucccgaggucaagaggugu
<SEQ ID NO. 1720;RNA;Artificial Sequence> uaugugaaaaagacaaugg
<SEQ ID NO. 1721;RNA;Artificial Sequence> ggaaggcucccagugcgcu
<SEQ ID NO. 1722;RNA;Artificial Sequence> uggauggccaucgagucac
<SEQ ID NO. 1723;RNA;Artificial Sequence> cugaauuacaguguguaca
<SEQ ID NO. 1724;RNA;Artificial Sequence> acaaccaacagugauguau
<SEQ ID NO. 1725;RNA;Artificial Sequence> ugguccuaugguguguuac
<SEQ ID NO. 1726;RNA;Artificial Sequence> cuaugggagauuguuagcu
<SEQ ID NO. 1727;RNA;Artificial Sequence> uuaggaggcacacccuacu
<SEQ ID NO. 1728;RNA;Artificial Sequence> ugcgggaugacuugugcag
<SEQ ID NO. 1729;RNA;Artificial Sequence> gaacucuacgagaagcugc
<SEQ ID NO. 1730;RNA;Artificial Sequence> ccccagggcuacagacugg
<SEQ ID NO. 1731;RNA;Artificial Sequence> gagaagccccugaacugug
<SEQ ID NO. 1732;RNA;Artificial Sequence> gaugaugagguguaugauc
<SEQ ID NO. 1733;RNA;Artificial Sequence> cuaaugagacaaugcuggc
<SEQ ID NO. 1734;RNA;Artificial Sequence> cgggagaagccuuaugaga
<SEQ ID NO. 1735;RNA;Artificial Sequence> aggccaucauuugcccaga
<SEQ ID NO. 1736;RNA;Artificial Sequence> auauugguguccuuaaaca
<SEQ ID NO. 1737;RNA;Artificial Sequence> agaauguuagaggagcgaa
<SEQ ID NO. 1738;RNA;Artificial Sequence> aagaccuacgugaauacca
<SEQ ID NO. 1739;RNA;Artificial Sequence> acgcuuuaugagaaguuua
<SEQ ID NO. 1740;RNA;Artificial Sequence> acuuaugcaggaauugacu
<SEQ ID NO. 1741;RNA;Artificial Sequence> uguucugcugaagaagcgg
<SEQ ID NO. 1742;RNA;Artificial Sequence> gccuaggacagaacaucug
<SEQ ID NO. 1743;RNA;Artificial Sequence> guauacccucuguuucccu
<SEQ ID NO. 1744;RNA;Artificial Sequence> uuucacuggcaugggagac
<SEQ ID NO. 1745;RNA;Artificial Sequence> cccuugacaccugcugaga
<SEQ ID NO. 1746;RNA;Artificial Sequence> aaaacaugccucugccaaa
<SEQ ID NO. 1747;RNA;Artificial Sequence> aggaugugauauauaagug
<SEQ ID NO. 1748;RNA;Artificial Sequence> guacauaugugcuguacac
<SEQ ID NO. 1749;RNA;Artificial Sequence> ccugggaccuucaccacug
<SEQ ID NO. 1750;RNA;Artificial Sequence> guagaucccaugcauggau
<SEQ ID NO. 1751;RNA;Artificial Sequence> ucuauguaguaugcucuga
<SEQ ID NO. 1752;RNA;Artificial Sequence> acucuaauaggacuguaua
<SEQ ID NO. 1753;RNA;Artificial Sequence> auacuguuuuaagaauggg
<SEQ ID NO. 1754;RNA;Artificial Sequence> gcugaaaucagaaugccug
<SEQ ID NO. 1755;RNA;Artificial Sequence> guuugugguuucauaugca
<SEQ ID NO. 1756;RNA;Artificial Sequence> aauaauauauuuuuuuaaa
<SEQ ID NO. 1757;RNA;Artificial Sequence> aaauguggacuucauagga
<SEQ ID NO. 1758;RNA;Artificial Sequence> aaggcgugaguacaauuag
741-3651

CA 02677068 2009-09-01
<SEQ ID NO. 1759;RNA;Artificial Sequence> guauaaugcauaacucauu
<SEQ ID NO. 1760;RNA;Artificial Sequence> uguuguccuagauauuuug
<SEQ ID NO. 1761.;RNA;Artificial Sequence> gauauuuaccuuuauguug
<SEQ ID NO. 1762;RNA;Artificial Sequence> gaaugcuauuaaauguuuu
<SEQ ID NO. 1763;RNA;Artificial Sequence> uccugugucaaaguaaaau
<SEQ ID NO. 1764;RNA;Artificial Sequence> uauuguuaauaaaccuaac
<SEQ ID NO. 1765;RNA;Artificial Sequence> caaugacccugauaguaca
<SEQ ID NO. 1766;RNA;Artificial Sequence> agguuaagugagagaacua
<SEQ ID NO. 1767;RNA;Artificial Sequence> auaugaauucuaacaaguc
<SEQ ID NO. 1768;RNA;Artificial Sequence> cauagguuaauauuuaaga
<SEQ ID NO. 1769;RNA;Artificial Sequence> acacugaaaaaucuaagug
<SEQ ID NO. 1770;RNA;Artificial Sequence> gauauaaaucagauucuuc
<SEQ ID NO. 1771;RNA;Artificial Sequence> cucucucaauuuuaucccu
<SEQ ID NO. 1772;RNA;Artificial Sequence> ucaccuguagcagccaguc
<SEQ ID NO. 1773;RNA;Artificial Sequence> cccguuucauuuagucaug
<SEQ ID NO. 1774;RNA;Artificial Sequence> gugaccacucugucuugug
<SEQ ID NO. 1775;RNA;Artificial Sequence> guuuccacagccugcaagu
<SEQ ID NO. 1776;RNA;Artificial Sequence> ucaguccaggaugcuaaca
<SEQ ID NO. 1777;RNA;Artificial Sequence> aucuaaaaauagacuuaaa
<SEQ ID NO. 1778;RNA;Artificial Sequence> aucucauugcuuacaagcc
<SEQ ID NO. 1779;RNA;Artificial Sequence> cuaagaaucuuuagagaag
<SEQ ID NO. 1780;RNA;Artificial Sequence> guauacauaaguuuaggau
<SEQ ID NO. 1781;RNA;Artificial Sequence> uaaaauaaugggauuuucu
<SEQ ID NO. 1782;RNA;Artificial Sequence> uuuucuuuucucugguaau
<SEQ ID NO. 1783;RNA;Artificial Sequence> uauugacuuguauauuuua
<SEQ ID NO. 1784;RNA;Artificial Sequence> aagaaauaacagaaagccu
<SEQ ID NO. 1785;RNA;Artificial Sequence> ugggugacauuugggagac
<SEQ ID NO. 1786;RNA;Artificial Sequence> caugugacauuuauauauu
<SEQ ID NO. 1787;RNA;Artificial Sequence> ugaauuaauaucccuacau
<SEQ ID NO. 1788;RNA;Artificial Sequence> uguauugcacauuguaaaa
<SEQ ID NO. 1789;RNA;Artificial Sequence> aaguuuuaguuuugaugag
<SEQ ID NO. 1790;RNA;Artificial Sequence> guugugaguuuaccuugua
<SEQ ID NO. 1791;RNA;Artificial Sequence> auacuguaggcacacuuug
<SEQ ID NO. 1792;RNA;Artificial Sequence> gcacugauauaucaugagu
<SEQ ID NO. 1793;RNA;Artificial Sequence> ugaauaaaugucuugccua
<SEQ ID NO. 1794;RNA;Artificial Sequence> acucacgucucaaaaaaaa
<SEQ ID NO. 1795;RNA;Artificial Sequence> ugaauugcgagauggauagggcuug
<SEQ ID NO. 1796;RNA;Artificial Sequence> gagugcccccagcccugcugauacc
<SEQ ID NO. 1797;RNA;Artificial Sequence> caaaugccuuuaagauacagccuuu
<SEQ ID NO. 1798;RNA;Artificial Sequence> ucccauccuaaucuacaaaggaaac
<SEQ ID NO. 1799;RNA;Artificial Sequence> caggaaaaaggaacuuaaaacuccc
<SEQ ID NO. 1800;RNA;Artificial Sequence> cugugcucagacagaaaugagacug
<SEQ ID NO. 1801;RNA;Artificial Sequence> guuacagccugcuucugugcuguuc
<SEQ ID NO. 1802;RNA;Artificial Sequence> ccuucuugccucuaacuuguaaaca
<SEQ ID NO. 1803;RNA;Artificial Sequence> aagacguaguaggacgaugcuaaug
<SEQ ID NO. 1804;RNA;Artificial Sequence> ggaaagucacaaaccgcuggguuuu
<SEQ ID NO. 1805;RNA;Artificial Sequence> uugaaaggauccuugggaccucaug
<SEQ ID NO. 1806;RNA;Artificial Sequence> gcacauuuguggaaacuggauggag
<SEQ ID NO. 1807;RNA;Artificial Sequence> gagauuuggggaagcauggacucuu
<SEQ ID NO. 1808;RNA;Artificial Sequence> uuagccagcuuaguucucuguggag
<SEQ ID NO. 1809;RNA;Artificial Sequence> gucagcuugcuccuuucuggaacug
<SEQ ID NO. 1810;RNA;Artificial Sequence> guggaaggugccauggacuugaucu
<SEQ ID NO. 1811;RNA;Artificial Sequence> uugaucaauucccuaccucuuguau
<SEQ ID NO. 1812;RNA;Artificial Sequence> ucugaugcugaaacaucucucaccu
<SEQ ID NO. 1813;RNA;Artificial Sequence> ugcauugccucuggguggcgccccc
<SEQ ID NO. 1814;RNA;Artificial Sequence> caugagcccaucaccauaggaaggg
<SEQ ID NO. 1815;RNA;Artificial Sequence> gacuuugaagccuuaaugaaccagc
<SEQ ID NO. 1816;RNA;Artificial Sequence> caccaggauccgcuggaaguuacuc
<SEQ ID NO. 1817;RNA;Artificial Sequence> caagaugugaccagagaaugggcua
<SEQ ID NO. 1818;RNA;Artificial Sequence> aaaaaaguuguuuggaagagagaaa
<SEQ ID NO. 1819;RNA;Artificial Sequence> aaggcuaguaagaucaauggugcuu
<SEQ ID NO. 1820;RNA;Artificial Sequence> uauuucugugaagggcgaguucgag
<SEQ ID NO. 1821;RNA;Artificial Sequence> ggagaggcaaucaggauacgaacca
<SEQ ID NO. 1822;RNA;Artificial Sequence> augaagaugcgucaacaagcuuccu
<SEQ ID NO. 1823;RNA;Artificial Sequence> uuccuaccagcuacuuuaacuauga
<SEQ ID NO. 1824;RNA;Artificial Sequence> acuguggacaagggagauaacguga
<SEQ ID NO. 1825;RNA;Artificial Sequence> aacauaucuuucaaaaagguauuga
<SEQ ID NO. 1826;RNA;Artificial Sequence> auuaaagaagaagaugcagugauuu
<SEQ ID NO. 1827;RNA;Artificial Sequence> uacaaaaaugguuccuucauccauu
<SEQ ID NO. 1828;RNA;Artificial Sequence> ucagugccccggcaugaaguaccug
<SEQ ID NO. 1829;RNA;Artificial Sequence> gauauucuagaaguacaccugccuc
<SEQ ID NO. 1830;RNA;Artificial Sequence> caugcucagccccaggaugcuggag
<SEQ ID NO. 1831;RNA;Artificial Sequence> guguacucggccagguauauaggag
741-3652

CA 02677068 2009-09-01
<SEQ ID NO. 1832;RNA;Artificial Sequence> ggaaaccucuucaccucggccuuca
<SEQ ID NO. 1833;RNA;Artificial Sequence> accaggcugauaguccggagaugug
<SEQ ID NO. 1834;RNA;Artificial Sequence> gaagcccagaaguggggaccugaau
<SEQ ID NO. 1835;RNA;Artificial Sequence> ugcaaccaucucuguacugcuugua
<SEQ ID NO. 1836;RNA;Artificial Sequence> augaacaauggugucugccaugaag
<SEQ ID NO. 1837;RNA;Artificial Sequence> gauacuggagaaugcauuugcccuc
<SEQ ID NO. 1838;RNA;Artificial Sequence> ccuggguuuaugggaaggacgugug
<SEQ ID NO. 1839;RNA;Artificial Sequence> gagaaggcuugugaacugcacacgu
<SEQ ID NO. 1840;RNA;Artificial Sequence> uuuggcagaacuuguaaagaaaggu
<SEQ ID NO. 1841;RNA;Artificial Sequence> ugcaguggacaagagggaugcaagu
<SEQ ID NO. 1842;RNA;Artificial Sequence> ucuuauguguucugucucccugacc
<SEQ ID NO. 1843;RNA;Artificial Sequence> cccuauggguguuccugugccacag
<SEQ ID NO. 1844;RNA;Artificial Sequence> ggcuggaagggucugcagugcaaug
<SEQ ID NO. 1845;RNA;Artificial Sequence> gaagcaugccacccugguuuuuacg
<SEQ ID NO. 1846;RNA;Artificial Sequence> gggccagauuguaagcuuaggugca
<SEQ ID NO. 1847;RNA;Artificial Sequence> agcugcaacaauggggagaugugug
<SEQ ID NO. 1848;RNA;Artificial Sequence> gaucgcuuccaaggaugucucugcu
<SEQ ID NO. 1849;RNA;Artificial Sequence> ucuccaggauggcaggggcuccagu
<SEQ ID NO. 1850;RNA;Artificial Sequence> ugugagagagaaggcauaccgagga
<SEQ ID NO. 1851;RNA;Artificial Sequence> augaccccaaagauaguggauuugc
<SEQ ID NO. 1852;RNA;Artificial Sequence> ccagaucauauagaaguaaacagug
<SEQ ID NO. 1853;RNA;Artificial Sequence> gguaaauuuaaucccauuugcaaag
<SEQ ID NO. 1854;RNA;Artificial Sequence> gcuucuggcuggccgcuaccuacua
<SEQ ID NO. 1855;RNA;Artificial Sequence> aaugaagaaaugacccuggugaagc
<SEQ ID NO. 1856;RNA;Artificial Sequence> ccggaugggacagugcuccauccaa
<SEQ ID NO. I857;RNA;Artificial Sequence> aaagacuuuaaccauacggaucauu
<SEQ ID NO. 1858;RNA;Artificial Sequence> uucucaguagccauauucaccaucc
<SEQ ID NO. 1859;RNA;Artificial Sequence> caccggauccuccccccugacucag
<SEQ ID NO. 1860;RNA;Artificial Sequence> ggaguuugggucugcagugugaaca
<SEQ ID NO. 1861;RNA;Artificial Sequence> acaguggcugggaugguggaaaagc
<SEQ ID NO. 1862;RNA;Artificial Sequence> cccuucaacauuucuguuaaaguuc
<SEQ ID NO. 1863;RNA;Artificial Sequence> cuuccaaagccccugaaugccccaa
<SEQ ID NO. 1864;RNA;Artificial Sequence> aacgugauugacacuggacauaacu
<SEQ ID NO. 1865;RNA;Artificial Sequence> uuugcugucaucaacaucagcucug
<SEQ ID NO. 1866;RNA;Artificial Sequence> gagccuuacuuuggggauggaccaa
<SEQ ID NO. 1867;RNA;Artificial Sequence> aucaaauccaagaagcuucuauaca
<SEQ ID NO. 1868;RNA;Artificial Sequence> aaacccguuaaucacuaugaggcuu
<SEQ ID NO. 1869;RNA;Artificial Sequence> uggcaacauauucaagugacaaaug
<SEQ ID NO. 1870;RNA;Artificial Sequence> gagauuguuacacucaacuauuugg
<SEQ ID NO. 1871;RNA;Artificial Sequence> gaaccucggacagaauaugaacucu
<SEQ ID NO. 1872;RNA;Artificial Sequence> ugugugcaacugguccgucguggag
<SEQ ID NO. 1873;RNA;Artificial Sequence> gaggguggggaagggcauccuggac
<SEQ ID NO. 1874;RNA;Artificial Sequence> ccugugagacgcuucacaacagcuu
<SEQ ID NO. 1875;RNA;Artificial Sequence> ucuaucggacucccuccuccaagag
<SEQ ID NO. 1876;RNA;Artificial Sequence> ggucuaaaucuccugccuaaaaguc
<SEQ ID NO. 1877;RNA;Artificial Sequence> cagaccacucuaaauuugaccuggc
<SEQ ID NO. 1878;RNA;Artificial Sequence> caaccaauauuuccaagcucggaag
<SEQ ID NO. 1879;RNA;Artificial Sequence> gaugacuuuuauguugaaguggaga
<SEQ ID NO. 1880;RNA;Artificial Sequence> agaaggucugugcaaaaaagugauc
<SEQ ID NO. 1881;RNA;Artificial Sequence> cagcagaauauuaaaguuccaggca
<SEQ ID NO. 1882;RNA;Artificial Sequence> aacuugacuucggugcuacuuaaca
<SEQ ID NO. 1883;RNA;Artificial Sequence> aacuuacaucccagggagcaguacg
<SEQ ID NO. 1884;RNA;Artificial Sequence> gugguccgagcuagagucaacacca
<SEQ ID NO. 1885;RNA;Artificial Sequence> aaggcccagggggaauggagugaag
<SEQ ID NO. 1886;RNA;Artificial Sequence> gaucucacugcuuggacccuuagug
<SEQ ID NO. 1887;RNA;Artificial Sequence> gacauucuuccuccucaaccagaaa
<SEQ ID NO. 1888;RNA;Artificial Sequence> aacaucaagauuuccaacauuacac
<SEQ ID NO. 1889;RNA;Artificial Sequence> cacuccucagcugugauuucuugga
<SEQ ID NO. 1890;RNA;Artificial Sequence> acaauauuggauggcuauucuauuu
<SEQ ID NO. 1891;RNA;Artificial Sequence> ucuucuauuacuauccguuacaagg
<SEQ ID NO. 1892;RNA;Artificial Sequence> guucaaggcaagaaugaagaccagc
<SEQ ID NO. 1893;RNA;Artificial Sequence> cacguugaugugaagauaaagaaug
<SEQ ID NO. 1894;RNA;Artificial Sequence> gccaccaucacucaguaucagcuca
<SEQ ID NO. 1895;RNA;Artificial Sequence> aagggccuagagccugaaacagcau
<SEQ ID NO. 1896;RNA;Artificial Sequence> uaccagguggacauuuuugcagaga
<SEQ ID NO. 1897;RNA;Artificial Sequence> aacaacauagggucaagcaacccag
<SEQ ID NO. 1898;RNA;Artificial Sequence> gccuuuucucaugaacuggugaccc
<SEQ ID NO. 1899;RNA;Artificial Sequence> cucccagaaucucaagcaccagcgg
<SEQ ID NO. 1900;RNA;Artificial Sequence> gaccucggaggggggaagaugcugc
<SEQ ID NO. 1901;RNA;Artiicial Sequence> cuuauagccauccuuggcucugcug
<SEQ ID NO. 1902;RNA;Artificial Sequence> ggaaugaccugccugacugugcugu
<SEQ ID NO. 1903;RNA;Artificial Sequence> uuggccuuucugaucauauugcaau
<SEQ ID NO. 1904;RNA;Artificial Sequence> uugaagagggcaaaugugcaaagga
741-3653

CA 02677068 2009-09-01
<SEQ ID NO. 1905;RNA;Artificial Sequence> agaauggcccaagccuuccaaaacg
<SEQ ID NO. 1906;RNA;Artificial Sequence> gugagggaagaaccagcugugcagu
<SEQ ID NO. 1907;RNA;Artificial Sequence> uucaacucagggacucuggcccuaa
<SEQ ID NO. 1908;RNA;Artificial Sequence> aacaggaaggucaaaaacaacccag
<SEQ ID NO. 1909;RNA;Artificial Sequence> gauccuacaauuuauccagugcuug
<SEQ ID NO. 1910;RNA;Artificial Sequence> gacuggaaugacaucaaauuucaag
<SEQ ID NO. 1911;RNA;Artificial Sequence> gaugugauuggggagggcaauuuug
<SEQ ID NO. 1912;RNA;Artificial Sequence> ggccaaguucuuaaggcgcgcauca
<SEQ ID NO. 1913;RNA;Artificial Sequence> aagaaggauggguuacggauggaug
<SEQ ID NO. 1914;RNA;Artificial Sequence> gcugccaucaaaagaaugaaagaau
<SEQ ID NO. 1915;RNA;Artificial Sequence> uaugccuccaaagaugaucacaggg
<SEQ ID NO. 1916;RNA;Artificial Sequence> gacuuugcaggagaacuggaaguuc
<SEQ ID NO. 1917;RNA;Artificial Sequence> cuuuguaaacuuggacaccauccaa
<SEQ ID NO. 1918;RNA;Artificial Sequence> aacaucaucaaucucuuaggagcau
<SEQ ID NO. 1919;RNA;Artificial Sequence> ugugaacaucgaggcuacuuguacc
<SEQ ID NO. 1920;RNA;Artificial Sequence> cuggccauugaguacgcgccccaug
<SEQ ID NO. 1921;RNA;Artificial Sequence> ggaaaccuucuggacuuccuucgca
<SEQ ID NO. 1922;RNA;Artificial Sequence> aagagccgugugcuggagacggacc
<SEQ ID NO. 1923;RNA;Artificial Sequence> ccagcauuugccauugccaauagca
<SEQ ID NO. 1924;RNA;Artificial Sequence> accgcguccacacuguccucccagc
<SEQ ID NO. 1925;RNA;Artificial Sequence> cagcuccuucacuucgcugccgacg
<SEQ ID NO. 1926;RNA;Artificial Sequence> guggcccggggcauggacuacuuga
<SEQ ID NO. 1927;RNA;Artificial Sequence> agccaaaaacaguuuauccacaggg
<SEQ ID NO. 1928;RNA;Artificial Sequence> gaucuggcugccagaaacauuuuag
<SEQ ID NO. 1929;RNA;Artificial Sequence> guuggugaaaacuauguggcaaaaa
<SEQ ID NO. 1930;RNA;Artificial Sequence> auagcagauuuuggauugucccgag
<SEQ ID NO. 1931;RNA;Artificial Sequence> ggucaagagguguaugugaaaaaga
<SEQ ID NO. 1932;RNA;Artificial Sequence> acaaugggaaggcucccagugcgcu
<SEQ ID NO. 1933;RNA;Artificial Sequence> uggauggccaucgagucacugaauu
<SEQ ID NO. 1934;RNA;Artificial Sequence> uacaguguguacacaaccaacagug
<SEQ ID NO. 1935;RNA;Artificial Sequence> gauguaugguccuaugguguguuac
<SEQ ID NO. 1936;RNA;Artificial Sequence> cuaugggagauuguuagcuuaggag
<SEQ ID NO. 1937;RNA;Artificial Sequence> ggcacacccuacugcgggaugacuu
<SEQ ID NO. 1938;RNA;Artificial Sequence> ugugcagaacucuacgagaagcugc
<SEQ ID NO. 1939;RNA;Artificial Sequence> ccccagggcuacagacuggagaagc
<SEQ ID NO. 1940;RNA;Artificial Sequence> ccccugaacugugaugaugaggugu
<SEQ ID NO. 1941;RNA;Artificial Sequence> uaugaucuaaugagacaaugcuggc
<SEQ ID NO. 1942;RNA;Artificial Sequence> cgggagaagccuuaugagaggccau
<SEQ ID NO. 1943;RNA;Artificial Sequence> ucauuugcccagauauugguguccu
<SEQ ID NO. 1944;RNA;Artificial Sequence> uuaaacagaauguuagaggagcgaa
<SEQ ID NO. 1945;RNA;Artificial Sequence> aagaccuacgugaauaccacgcuuu
<SEQ ID NO. 1946;RNA;Artificial Sequence> uaugagaaguuuacuuaugcaggaa
<SEQ ID NO. 1947;RNA;Artificial Sequence> auugacuguucugcugaagaagcgg
<SEQ ID NO. 1948;RNA;Artificial Sequence> gccuaggacagaacaucuguauacc
<SEQ ID NO. I949;RNA;Artificial Sequence> ccucuguuucccuuucacuggcaug
<SEQ ID NO. 1950;RNA;Artificial Sequence> gggagacccuugacaccugcugaga
<SEQ ID NO. 1951;RNA;Artificial Sequence> aaaacaugccucugccaaaggaugu
<SEQ ID NO. 1952;RNA;Artificial Sequence> ugauauauaaguguacauaugugcu
<SEQ ID NO. 1953;RNA;Artificial Sequence> uguacaccugggaccuucaccacug
<SEQ ID NO. 1954;RNA;Artificial Sequence> guagaucccaugcauggaucuaugu
<SEQ ID NO. 1955;RNA;Artificial Sequence> uaguaugcucugacucuaauaggac
<SEQ ID NO. I956;RNA;Artificial Sequence> cuguauauacuguuuuaagaauggg
<SEQ ID NO. 1957;RNA;Artificial Sequence> gcugaaaucagaaugccuguuugug
<SEQ ID NO. 1958;RNA;Artificial Sequence> gguuucauaugcaauaauauauuuu
<SEQ ID NO. 1959;RNA;Artificial Sequence> uuuuaaaaauguggacuucauagga
<SEQ ID NO. 1960;RNA;Artificial Sequence> aaggcgugaguacaauuaguauaau
<SEQ ID NO. 1961;RNA;Artificial Sequence> ugcauaacucauuguuguccuagau
<SEQ ID NO. 1962;RNA;Artificial Sequence> uauuuugauauuuaccuuuauguug
<SEQ ID NO. 1963;RNA;Artificial Sequence> gaaugcuauuaaauguuuuccugug
<SEQ ID NO. 1964;RNA;Artificial Sequence> gucaaaguaaaauauuguuaauaaa
<SEQ ID NO. 1965;RNA;Artificial Sequence> accuaacaaugacccugauaguaca
<SEQ ID NO. 1966;RNA;Artificial Sequence> agguuaagugagagaacuauaugaa
<SEQ ID NO. 1967;RNA;Artificial Sequence> auucuaacaagucauagguuaauau
<SEQ ID NO. 1968;RNA;Artificial Sequence> uuuaagacacugaaaaaucuaagug
<SEQ ID NO. 1969;RNA;Artificial Sequence> gauauaaaucagauucuucucucuc
<SEQ ID NO. 1970;RNA;Artificial Sequence> caauuuuaucccucaccuguagcag
<SEQ ID NO. 1971;RNA;Artificial Sequence> gccagucccguuucauuuagucaug
<SEQ ID NO. 1972;RNA;Artificial Sequence> gugaccacucugucuuguguuucca
<SEQ ID NO. 1973;RNA;Artificial Sequence> acagccugcaagucaguccaggaug
<SEQ ID NO. 1974;RNA;Artificial Sequence> gcuaacaucuaaaaauagacuuaaa
<SEQ ID NO. 1975;RNA;Artificial Sequence> aucucauugcuuacaagccuaagaa
<SEQ ID NO. 1976;RNA;Artificial Sequence> aucuuuagagaaguauacauaaguu
<SEQ ID NO. 1977;RNA;Artificial Sequence> uuaggauaaaauaaugggauuuucu
741-3654

CA 02677068 2009-09-01
<SEQ ID NO. 1978;RNA;Artificial Sequence> uuuucuuuucucugguaauauugac
<SEQ ID NO. 1979;RNA;Artificial Sequence> cuuguauauuuuaagaaauaacaga
<SEQ ID NO. 1980;RNA;Artificial Sequence> aaagccugggugacauuugggagac
<SEQ ID NO. 1981;RNA;Artificial Sequence> caugugacauuuauauauugaauua
<SEQ ID NO. 1982;RNA;Artificial Sequence> aauaucccuacauguauugcacauu
<SEQ ID NO. 1983;RNA;Artificial Sequence> uguaaaaaguuuuaguuuugaugag
<SEQ ID NO. 1984;RNA;Artificial Sequence> guugugaguuuaccuuguauacugu
<SEQ ID NO. 1985;RNA;Artificial Sequence> uaggcacacuuugcacugauauauc
<SEQ ID NO. 1986;RNA;Artificial Sequence> caugagugaauaaaugucuugccua
R121 - 5469
<120> NUCLEIC ACID COMPOUNDS FOR INHIBITING
FGFR GENE EXPRESSION AND USES THEREOF
<130> 07-R121PCT
<210> 1
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 1
cuacacaaau cagcgauuut t 21
<210> 2
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 2
aaaucgcuga uuuguguagt t 21
<210> 3
<211> 25
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 3
cuacacaaau cagcgauuuc caugt 25
<210> 4
<211> 27
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3655

CA 02677068 2009-09-01
<400> 4
acauggaaau cgcugauuug uguaguc 27
<210> 5
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 5
cuacacaaau cag 13
<210> 6
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 6
gauuuccaugt 11
<210> 7
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 7
ggaucuuauu ucuucggagt t 21
<210> 8
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 8
cuccgaagaa auaagaucct t 21
<210> 9
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 9
741-3656

CA 02677068 2009-09-01
ggaucuuauu u 11
<210> 10
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 10
cuucggagtt 10
<210> 11
<211> 27
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 11
cauugucucc gaagaaauaa gauccuu 27
<210> 12
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 12
ggaucuua 8
<210> 13
<211> 17
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 13
uuucuucgga gacaatg 17
<210> 14
<211> 16
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
741-3657

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 14
uucuucggag acaatg 16
<210> 15
<211> 15
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 15
ucuucggaga caatg 15
<210> 16
<211> 14
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 16
cuucggagac aatg 14
<210> 17
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 17
uucggagaca atg 13
<210> 18
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 18
ucggagacaatg 12
<210> 19
<211> it
741-3658

CA 02677068 2009-09-01
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 19
cggagacaat g 11
<210> 20
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 20
ggaucuuau 9
<210> 21
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 21
ggaucuuauu 10
<210> 22
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 22
ggaucuuauu u 11
<210> 23
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3659

CA 02677068 2009-09-01
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 23
ggaucuuauu uc 12
<210> 24
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (3) <223> LNA-A
<400> 24
cuacacaa 8
<210> 25
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (8) <223> LNA-A
<400> 25
aucagcgauu utt 13
<210> 26
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-A
<400> 26
ucagcgauuu tt 12
<210> 27
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-A
741-3660

CA 02677068 2009-09-01
<400> 27
cagcgauuutt 11
<210> 28
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (5) <223> LNA-A
<400> 28
agcgauuutt 10
<210> 29
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (4)
<223> LNA-A
<400> 29
gcgauuutt 9
<210> 30
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 30
cgauuutt 8
<210> 31
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-A
<400> 31
gauuutt 7
<210> 32
741-3661

CA 02677068 2009-09-01
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 32
cuacacaaa 9
<210> 33
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (3) <223> LNA-A
<400> 33
cuacacaaau 10
<210> 34
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 34
cuacacaaau c 11
<210> 35
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 35
cuacacaaau ca 12
<210> 36
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
741-3662

CA 02677068 2009-09-01
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 36
cuacacaaau cag 13
<210> 37
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 37
cuacacaaau cagc 14
<210> 38
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 38
ggaucuuauu ucu 13
<210> 39
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 39
ggaucuuauu ucuu 14
<210> 40
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
741-3663

CA 02677068 2009-09-01
<223> LNA-G
<220>
<221> modified base
<222> (8)
<223> LNA-A
<400> 40
ggaucuua 8
<210> 41
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (9)
<223> LNA-U
<400> 41
ggaucuuau 9
<210> 42
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (10)
<223> LNA-U
<400> 42
ggaucuuauu 10
<210> 43
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (11)
<223> LNA-U
741-3664

CA 02677068 2009-09-01
<400> 43
ggaucuuauu u 11
<210> 44
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<220>
<221> modified-base
<222> (12) <223> LNA-C
<400> 44
ggaucuuauu uc 12
<210> 45
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (13)
<223> LNA-U
<400> 45
ggaucuuauu ucu 13
<210> 46
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (14) <223> LNA-U
<400> 46
ggaucuuauu ucuu 14
<210> 47
<211> 13
<212> DNA
741-3665

CA 02677068 2009-09-01
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (8)
<223> LNA-G
<400> 47
uuucuucgga gtt 13
<210> 48
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 48
uucuucggagtt 12
<210> 49
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-G
<400> 49
ucuucggagtt 11
<210> 50
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
741-3666

CA 02677068 2009-09-01
<221> modified base
<222> (5)
<223> LNA-G
<400> 50
cuucggagtt 10
<210> 51
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (4)
<223> LNA-G
<400> 51
uucggagtt 9
<210> 52
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-G
<400> 52
ucggagtt 8
<210> 53
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<400> 53
cggagtt 7
<210> 54
<211> 13
741-3667

CA 02677068 2009-09-01
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified-base
<222> (8) <223> LNA-G
<400> 54
uuucuucgga gtt 13
<210> 55
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 55
uucuucggagtt 12
<210> 56
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (6)
<223> LNA-G
<400> 56
741-3668

CA 02677068 2009-09-01
ucuucggagtt 11
<210> 57
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-C
<220>
<221> modified base
<222> (5)
<223> LNA-G
<400> 57
cuucggagtt 10
<210> 58
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified-base
<222> (4) <223> LNA-G
<400> 58
uucggagtt 9
<210> 59
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
741-3669

CA 02677068 2009-09-01
<221> modified base
<222> (3)
<223> LNA-G
<400> 59
ucggagtt 8
<210> 60
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-C
<220>
<221> modified-base
<222> (2) <223> LNA-G
<400> 60
cggagtt 7
<210> 61
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (2) <223> LNA-G
<220>
<221> modified-base
<222> (16) <223> LNA-G
<400> 61
ggaucuuauu ucuucggagt t 21
<210> 62
<211> 25
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 62
741-3670

CA 02677068 2009-09-01
ggaucuuauu ucuucggaga caatg 25
<SEQ ID NO. 63;RNA;Artificial Sequence>guauuuugaugaggaguucacggcc
<SEQ ID NO. 64;RNA;Artificial Sequence>ggcccagaugaucaccaucacacca
<SEQ ID NO. 65;RNA;Artificial Sequence>gggaagaaaacuauccugcggguuu
<SEQ ID NO. 66;RNA;Artificial Sequence>guuuuaauuuauuucauccaguuug
<SEQ ID NO. 67;RNA;Artificial Sequence>acguagggaaauguuaaggacuucu
<SEQ ID NO. 68;RNA;Artificial Sequence>ccaggguuuacccagugggacagag
<SEQ ID NO. 69;RNA;Artificial Sequence>agcaagguuuaaauuuguuauugug
<SEQ ID NO. 70;RNA;Artificial Sequence>uguauuauguuguucaaaugcauuu
<SEQ ID NO.7I;RNA;Artificial Sequence>uuuuaaucuuugugaeaggaaagec
<SEQ ID NO. 72;RNA; Artificial Sequence>uuaaucuuugugacaggaaagcccu
<SEQ ID NO.73;RNA;Artificial Sequence>gcugcuuaugucucccagcauggcc
<SEQ ID NO. 74;RNA;Artificial Sequence> aaguguuucagaagcuucucccuga
<SEQ ID NO.75;RNA;Artificial Sequence> gaccaucaauaaggaagaagcccuu
<SEQ ID NO. 76;RNA;Artificial Sequence>ccaucaauaaggaagaagcccuuca
<SEQ ID NO. 77;RNA;Artificial Sequence>ucaauaaggaagaagcccuucagcg
<SEQ ID NO. 78;RNA;Artificial Sequence>aauaaggaagaagcccuucagcggc
<SEQ ID NO. 79;RNA;Artificial Sequence>aggaagaagcccuucagcggccagu
<SEQ ID NO. 80;RNA;Artificial Sequence>gcauaacuaaaggugaaaagcuccg
<SEQ ID NO. 81;RNA;Artificial Sequence>cauaacuaaaggugaaaagcuccgg
<SEQ ID NO. 82;RNA;Artificial Sequence>cuacaucacgccagucaacagucug
<SEQ ID NO. 83;RNA;Artificial Sequence>acuggauuuaagcagaguucaaaag
<SEQ ID NO. 84;RNA;Artificial Sequence>cuggauuuaagcagaguucaaaagc
<SEQ ID NO. 85;RNA;Artificial Sequence>gauuuaagcagaguucaaaagcccu
<SEQ ID NO. 86;RNA;Artificial Sequence>auuuaagcagaguucaaaagcccuu
<SEQ ID NO. 87;RNA;Artificial Sequence>uuaagcagaguucaaaagcccuuca
<SEQ ID NO. 88;RNA;Artificial Sequence>uaagcagaguucaaaagcccuucag
<SEQ ID NO. 89;RNA;Artificial Sequence>agcagaguucaaaagcccuucagcg
<SEQ ID NO. 90;RNA;Artificial Sequence>cucagggucugagugaagccgcucg
<SEQ ID NO. 91;RNA;Artificial Sequence>caagcaacuacaucacgccagucaa
<SEQ ID NO. 92;RNA;Artificial Sequence>aucaauggcagcuucuuggugcgug
<SEQ ID NO. 93;RNA;Artificial Sequence>uuccagcccacauuggauucaucag
<SEQ ID NO. 94;RNA;Artificial Sequence>cagcugagaauguggaauaccuaag
<SEQ ID NO. 95;RNA;Artificial Sequence> aacguaucuccuaauuugaggcuca
<SEQ ID NO. 96;RNA;Artificial Sequence>ccuaaaauaauuucucuacaauugg
<SEQ ID NO. 97;RNA;Artificial Sequence>uggaagauucagcuaguuaggagcc
<SEQ ID NO. 98;RNA;Artificial Sequence>uuaaacucuccuagucaauauccac
<SEQ ID NO. 99;RNA;Artificial Sequence>cagccuacaguuauguucagucaca
<SEQ ID NO. 100;RNA;Artificial Sequence> guuauguucagucacacacacauac
<SEQ ID NO. 101;RNA;Artificial Sequence> cacauacaaaauguuccuuuugcuu
<SEQ ID NO. 102;RNA;Artificial Sequence> uccuuuugcuuuuaaaguaauuuuu
<SEQ ID NO. 103;RNA;Artificial Sequence> ugaccugugaagcaacagucaaugg
<SEQ ID NO. 104;RNA;Artificial Sequence> cuaucucacacaucgacaaaccaau
<SEQ ID NO. 105;RNA;Artificial Sequence> uguccucaauuguacugcuaccacu
<SEQ ID NO. 106;RNA;Artificial Sequence> aaaccguagcuggcaagcggucuua
<SEQ ID NO. 107;RNA;Artificial Sequence> uagcuggcaagcggucuuaccggcu
<SEQ ID NO. 108;RNA;Artificial Sequence> uuguaugguuaaaagauggguuacc
<SEQ ID NO. 109;RNA;Artificial Sequence> ugguuaaaagauggguuaccugcga
<SEQ ID NO. I l0;RNA;Artificial Sequence> cagggaauuauacaaucuugcugag
<SEQ ID NO. I11;RNA;Artificial Sequence> acaaucuugcugagcauaaaacagu
<SEQ ID NO. 112;RNA;Artificial Sequence> ccaauaaugaagaguccuuuauccu
<SEQ ID NO. 113;RNA;Artificial Sequence> acuuuggauguuccaacgcaaguug
<SEQ ID NO. 114;RNA;Artificial Sequence> aaugcuuccacuaaacugaaaccau
<SEQ ID NO. 115;RNA;Artificial Sequence> gagaaaguuugacuuuguuaaauau
<SEQ ID NO. 116;RNA;Artificial Sequence> aaagaacuacuguauauuaaaaguu
<SEQ ID NO. 117;RNA;Artificial Sequence> uuagaaauacggguuuugacuuaac
<SEQ ID NO. 118;RNA;Artificial Sequence> aacauggguacagcaaacucagcac
<SEQ ID NO. 119;RNA;Artificial Sequence> aaagacacagaagaugcugaccuca
<SEQ ID NO. I20;RNA;Artificial Sequence> uaguagggagguuuauucagaucgc
<SEQ ID NO. 121;RNA;Artificial Sequence> gccuucugcagcaggguucugggau
<SEQ ID NO. 122;RNA;Artificial Sequence> ggucugguacauauuggaaauuaug
<SEQ ID NO. 123;RNA;Artificial Sequence> cuaguccuuccgauggaagcacuag
<SEQ ID NO. I24;RNA;Artificial Sequence> ccagugaauauuguuuuuaugugga
<SEQ ID NO. 125;RNA;Artificial Sequence> augaauucaaguuggaauugguaga
<SEQ ID NO. 126;RNA;Artificial Sequence> caggacacagauuuagacuuggaga
<SEQ ID NO. 127;RNA;Artificial Sequence> cucaaagcacaguuacaguauucca
<SEQ ID NO. 128;RNA;Artificial Sequence> accacugccaccacugaugaauuaa
<SEQ ID NO. 129;RNA;Artificial Sequence> gaaacuacuagugccacaucaucac
<SEQ ID NO. 130;RNA;Artificial Sequence> aagucggacagccucaccaaacaga
<SEQ ID NO. 131;RNA;Artificial Sequence> gaaagcgaaaaauggaacaugaugg
<SEQ ID NO. 132;RNA;Artificial Sequence> cccucugauuuagcauguagacugc
<SEQ ID NO. 133;RNA;Artificial Sequence> ugagcuauuuaaggaucuauuuaug
741-3671

CA 02677068 2009-09-01
<SEQ ID NO. 134;RNA;Artificial Sequence> aaaaggugaaaaagcacuauuauca
<SEQ ID NO. 135;RNA;Artificial Sequence> gaaaaagcacuauuaucaguucugc
<SEQ ID NO. 136;RNA;Artificial Sequence> ggcugaaaagaaagauuaaaccuac
<SEQ ID NO. 137;RNA;Artificial Sequence> uaaacccuuauaauaaaauccuucu
<SEQ ID NO. 138;RNA;Artificial Sequence> cauacuauuagccaaugcuguagac
<SEQ ID NO. 139;RNA;Artificial Sequence> gacagaagcauuuugauaggaauag
<SEQ ID NO. 140;RNA;Artificial Sequence> agagcaaauaagauaauggcccuga
<SEQ ID NO. 141;RNA;Artificial Sequence> ccaacauuuuucucuuccucaagca
<SEQ ID NO. 142;RNA;Artificial Sequence> uuaaguaugagaaaaguucagccca
<SEQ ID NO. 143;RNA;Artificial Sequence> caggaauaaagauggcugcugaacc
<SEQ ID NO. 144;RNA;Artificial Sequence> aauuugaaugaccaaguucucuuca
<SEQ ID NO. 145;RNA;Artificial Sequence> auguauaaagauagccagccuagag
<SEQ ID NO. 146;RNA;Artificial Sequence> ggcuguaacuaucucugugaagugu
<SEQ ID NO. 147;RNA;Artificial Sequence> ucugugaagugugagaaaauuucaa
<SEQ ID NO. 148;RNA;Artificial Sequence> ccuuuaaggaaaugaauccuccuga
<SEQ ID NO. 149;RNA;Artificial Sequence> aaggauacaaaaagugacaucauau
<SEQ ID NO. 150;RNA;Artificial Sequence> agaugcaauuugaaucuucaucaua
<SEQ ID NO. 151;RNA;Artificial Sequence> guucaaaacgaagacuagcuauuaa
<SEQ ID NO. 152;RNA;Artificial Sequence> gugaaaccucaucucuacuaaaaau
<SEQ ID NO. 153;RNA;Artificial Sequence> acgaaagagaagcucuaucucgccu
<SEQ ID NO. 154;RNA;Artificial Sequence> cuccacaagcgccuucgguccaguu
<SEQ ID NO. 155;RNA;Artificial Sequence> gagaagauuccaaagauguagccgc
<SEQ ID NO. 156;RNA;Artificial Sequence> aaucuggauucaaugaggagacuug
<SEQ ID NO. 157;RNA;Artificial Sequence> agaacagauuugagaguagugagga
<SEQ ID NO. 158;RNA;Artificial Sequence> ccagagcugugcagaugaguacaaa
<SEQ ID NO. 159;RNA;Artificial Sequence> ccucagauuguuguuguuaaugggc
<SEQ ID NO. 160;RNA;Artificial Sequence> cuauuuuaauuauuuuuaauuuauu
<SEQ ID NO. 161;RNA;Artificial Sequence> uuuaauuuauuaauauuuaaauaug
<SEQ ID NO. 162;RNA;Artificial Sequence> augcaguuugaauauccuuuguuuc
<SEQ ID NO. 163;RNA;Artificial Sequence> caugcugcuggcgucuaaguguuug
<SEQ ID NO. 164;RNA;Artificial Sequence> agaugugcauuucaccugugacaaa
<SEQ ID NO. 165;RNA;Artificial Sequence> ucaaaaccugugccaggcugaauua
<SEQ ID NO. 166;RNA;Artificial Sequence> gaauguggguagucauucuuacaau
<SEQ ID NO. 167;RNA;Artificial Sequence> auguggguagucauucuuacaauug
<SEQ ID NO. 168;RNA;Artificial Sequence> ugaaaaugagcaucagagaguguac
<SEQ ID NO. 169;RNA;Artificial Sequence> uugcuuuucauguagaacucagcag
<SEQ ID NO. 170;RNA;Artificial Sequence> uguauuucuauauuuauuuucagua
<SEQ ID NO. 171;RNA;Artificial Sequence> uuugauuaauguuucuuaaauggaa
<SEQ ID NO. 172;RNA;Artificial Sequence> caacguguauagugccuaaaauugu
<SEQ ID NO. 173;RNA;Artificial Sequence> cauauccuuggcuacuaacaucugg
<SEQ ID NO. 174;RNA;Artificial Sequence> uacuaacaucuggagacugugagcu
<SEQ ID NO. 175;RNA;Artificial Sequence> cauaaguugugugcuuuuuauuaau
<SEQ ID NO. 176;RNA;Artificial Sequence> gcaucauuuuggcucuucuuacauu
<SEQ ID NO. 177;RNA;Artificial Sequence> gcucuucuuacauuuguaaaaaugu
<SEQ ID NO. 178;RNA;Artificial Sequence> agauuaggucaucuuaauucauauu
<SEQ ID NO. 179;RNA;Artificial Sequence> auggaauugaaagaacuaaucauga
<SEQ ID NO. 180;RNA;Artificial Sequence> cacacucauuccuucugcucuuggg
<SEQ ID NO. 181;RNA;Artificial Sequence> uguagagguaaccaguagcuuugag
<SEQ ID NO. 182;RNA;Artificial Sequence> caaccacaugccacguaauauuuca
<SEQ ID NO. 183;RNA;Artificial Sequence> ucggaaacaaguuauucucuucacu
<SEQ ID NO. 184;RNA;Artificial Sequence> acucccaauaacuaaugcuaagaaa
<SEQ ID NO. 185;RNA;Artificial Sequence> aaugcuaagaaaugcugaaaaucaa
<SEQ ID NO. 186;RNA;Artificial Sequence> gucuuucucuaaauaugauuacuuu
<SEQ ID NO. I87;RNA;Artificial Sequence> ugaauuucaggcauuuuguucuaca
<SEQ ID NO. 188;RNA;Artificial Sequence> cgauucccucucacccgggacucuc
<SEQ ID NO. 189;RNA;Artificial Sequence> aggaaagugaaccuuuaaaguaaag
<SEQ ID NO. 190;RNA;Artificial Sequence> gaggcugcaugcucuggaagccugg
<SEQ ID NO. 191;RNA;Artificial Sequence> ucucugaacagaaaacaaaagagag
<SEQ ID NO. 192;RNA;Artificial Sequence> aacuuggcuguaaucaguuaugccg
<SEQ ID NO. 193;RNA;Artificial Sequence> agaagccaaaauuaaaagaagucca
<SEQ ID NO. 194;RNA;Artificial Sequence> auuaaaagaaguccaggugagguua
<SEQ ID NO. 195;RNA;Artificial Sequence> gaauccggauuaucgggaagaggac
<SEQ ID NO. 196;RNA;Artificial Sequence> aaugugacaucaaagcaaguauugu
<SEQ ID NO. I97;RNA;Artificial Sequence> caucaaagcaaguauuguagcacuc
<SEQ ID NO. 198;RNA;Artificial Sequence> agagagagaaaacaaaaccacaaau
<SEQ ID NO. 199;RNA;Artificial Sequence> ucgcuguaguauuuaagcccauaca
<SEQ ID NO. 200;RNA;Artificial Sequence> cgcuguaguauuuaagcccauacag
<SEQ ID NO.201;RNA;Artificial Sequence> auuuaagcccauacagaaaccuucc
<SEQ ID NO. 202;RNA;Artificial Sequence> auuaaaauaaacaugguauaccuac
<SEQ ID NO. 203;RNA;Artificial Sequence> cuguucugaucggccaguuuucgga
<SEQ ID NO. 204;RNA;Artificial Sequence> aaauaauuugaacuuuggaacaggg
<SEQ ID NO. 205;RNA;Artificial Sequence> ugcgaccuuaauuuaacuuuccagu
<SEQ ID NO. 206;RNA;Artificial Sequence> cugagaaagcuaaaguuugguuuug
741-3672

CA 02677068 2009-09-01
<SEQ ID NO. 207;RNA;Artificial Sequence> aguaaagaugcuacuucccacugua
<SEQ ID NO. 208;RNA;Artificial Sequence> cugcuuaauugcugauaccauauga
<SEQ ID NO. 209;RNA;Artificial Sequence> uaccauaugaaugaaacaugggcug
<SEQ ID NO. 210;RNA;Artificial Sequence> aacuuucuuauccaacuuuuucaua
<SEQ ID NO.211;RNA;Artificial Sequence> ccuugcaugacaucaugaggccgga
<SEQ ID NO. 212;RNA;Artificial Sequence> ugaauuuguauaugacugcauuugu
<SEQ ID NO. 213;RNA;Artificial Sequence> gaauccuaguagaauguuuacuacc
<SEQ ID NO. 214;RNA;Artificial Sequence> gaaagggaagaauuuuuugaugaaa
<SEQ ID NO. 215;RNA;Artificial Sequence> uaucggcaugccagugugugaauuu
<SEQ ID NO. 216;RNA;Artificial Sequence> caccucauaguagagcaauguaugu
<SEQ ID NO. 217;RNA;Artificial Sequence> ccagaauugccaaagcacauauaua
<SEQ ID NO. 218;RNA;Artificial Sequence> uggugaucuggguaauaguuucucc
<SEQ ID NO. 219;RNA;Artificial Sequence> gaucuggguaauaguuucuccaaau
<SEQ ID NO. 220;RNA;Artificial Sequence> ggaugugaugaauacuuccuagaaa
<SEQ ID NO. 221;RNA;Artificial Sequence> cauuuccacagcuacaccauauaug
<SEQ ID NO. 222;RNA;Artificial Sequence> acagcuacaccauauaugaauggag
<SEQ ID NO. 223;RNA;Artificial Sequence> ugcaguucuuacacgagaagaagau
<SEQ ID NO. 224;RNA;Artificial Sequence> acgagaagaagaucauuuacaggga
<SEQ ID NO. 225;RNA;Artificial Sequence> cgagaagaagaucauuuacagggac
<SEQ ID NO. 226;RNA;Artificial Sequence> aagaagaucauuuacagggaccuga
<SEQ ID NO. 227;RNA;Artificial Sequence> agaggaagagguguuugacugcauc
<SEQ ID NO. 228;RNA;Artificial Sequence> gaggaagagguguuugacugcaucg
<SEQ ID NO. 229;RNA;Artificial Sequence> cuacuuugagggcgaguucacaggg
<SEQ ID NO. 230;RNA;Artificial Sequence> agggcaucuccuggcaccucugucc
<SEQ ID NO. 231;RNA;Artificial Sequence> ggagugauaugguuugucuuuuuaa
<SEQ ID NO. 232;RNA;Artificial Sequence> gagugauaugguuugucuuuuuaag
<SEQ ID NO. 233;RNA;Artificial Sequence> ugcaguaaagauccuaaagguuguc
<SEQ ID NO. 234;RNA;Artificial Sequence> aguaaagauccuaaagguugucgac
<SEQ ID NO. 235;RNA;Artificial Sequence> ugacaaaggacaaccuggcaauugu
<SEQ ID NO. 236;RNA;Artificial Sequence> gcaauugugacccaguggugcgagg
<SEQ ID NO. 237;RNA;Artificial Sequence> aacaucauccauagagacaugaaau
<SEQ ID NO. 238;RNA;Artificial Sequence> ugaaauccaacaauauauuucucca
<SEQ ID NO. 239;RNA;Artificial Sequence> aacaauauauuucuccaugaaggcu
<SEQ ID NO. 240;RNA;Artificial Sequence> aacaguaaagucacgcuggaguggu
<SEQ ID NO. 241;RNA;Artificial Sequence> ugugaagaaaguaaaggaagagagg
<SEQ ID NO. 242;RNA; Artificial Sequence> cuuccgagccauccuugcaucgggc
<SEQ ID NO.243;RNA;Artificial Sequence> aauggagguugaauauccuacugug
<SEQ ID NO. 244;RNA;Artificial Sequence> ggagguugaauauccuacuguguaa
<SEQ ID NO. 245;RNA;Artificial Sequence> auuuugaguuuucccuuguagugua
<SEQ ID NO. 246;RNA;Artificial Sequence> uauccuguuuguucuuuguugauug
<SEQ ID NO. 247;RNA;Artificial Sequence> ccuguuuguucuuuguugauugaaa
<SEQ ID NO. 248;RNA;Artificial Sequence> cucuacagccuucuuuuucuuccau
<SEQ ID NO. 249;RNA;Artificial Sequence> ucuuccauagcuaaucuuccuucua
<SEQ ID NO. 250;RNA;Artificial Sequence> auaaucuuccuguugaaugcuucau
<SEQ ID NO. 25 1;RNA;Artificial Sequence> uaaucuuccuguugaaugcuucaug
<SEQ ID NO. 252;RNA;Artificial Sequence> cuucaugacuugaauucuacuuuga
<SEQ ID NO. 253;RNA; Artificial Sequence> aagagggagagaagcaacuacagac
<SEQ ID NO. 254;RNA;Artificial Sequence> cgucuccuaccagaccaaggucaac
<SEQ ID NO. 255;RNA; Artificial Sequence> gaucaaucggcccgacuaucucgac
<SEQ ID NO. 256;RNA;Artificial Sequence> ggacgaacauccaaccuucccaaac
<SEQ ID NO. 257;RNA;Artificial Sequence> agggucggaacccaagcuuagaacu
<SEQ ID NO. 258;RNA;Artificial Sequence> ucggaacccaagcuuagaacuuuaa
<SEQ ID NO. 259;RNA;Artificial Sequence> acccaagcuuagaacuuuaagcaac
<SEQ ID NO. 260;RNA;Artificial Sequence> gaacuuuaagcaacaagaccaccac
<SEQ ID NO. 261;RNA;Artificial Sequence> acuauucaguggcgagaaauaaagu
<SEQ ID NO. 262;RNA;Artificial Sequence> cuauucaguggcgagaaauaaaguu
<SEQ ID NO. 263;RNA;Artificial Sequence> aaacacagauaacaggaaaugaucc
<SEQ ID NO. 264;RNA;Artificial Sequence> cuuaagaaaagagaagaaaugaaac
<SEQ ID NO. 265;RNA;Artificial Sequence> cugaaggaguguguuuccauccucc
<SEQ ID NO. 266;RNA;Artificial Sequence> ucaccgcgggacugaaaaucuuuga
<SEQ ID NO. 267;RNA;Artificial Sequence> agcagaaauaagcgugccguucagg
<SEQ ID NO. 268;RNA;Artificial Sequence> aagcgugccguucaggguccagaag
<SEQ ID NO. 269;RNA;Artificial Sequence> agaaacagucacucaagacugcuug
<SEQ ID NO. 270;RNA;Artificial Sequence> agaggaagaagguccaugucuuugg
<SEQ ID NO. 271;RNA;Artificial Sequence> uguauucaaaauaugccugaaacac
<SEQ ID NO. 272;RNA; Artificial Sequence> auuuuccucccuuucucuguaccuc
<SEQ ID NO.273;RNA;Artificial Sequence> caaagaaagauagagcaagacaaga
<SEQ ID NO. 274;RNA;Artificial Sequence> aagaaagauagagcaagacaagaaa
<SEQ ID NO. 275;RNA;Artificial Sequence> gaaagcauuuguuuguacaagaucc
<SEQ ID NO. 276;RNA;Artificial Sequence> ugaguuaaacgaacguacuugcaga
<SEQ ID NO. 277;RNA;Artificial Sequence> acugauacagaacgaucgauacaga
<SEQ ID NO. 278;RNA;Artificial Sequence> auauuauauauauauaaaaauaaau
<SEQ ID NO. 279;RNA;Artificial Sequence> auuauauauauauaaaaauaaauau
741-3673

CA 02677068 2009-09-01
<SEQ ID NO. 280;RNA;Artificial Sequence> ucacuggauguauuugacugcugug
<SEQ ID NO. 281;RNA;Artificial Sequence> cagggaagaggaggagaugagagac
<SEQ ID NO. 282;RNA;Artificial Sequence> augaucuuuuuuuugucccacuugg
<SEQ ID NO. 283;RNA;Artificial Sequence> ggccgugaacuccucaucaaaauaccu
<SEQ ID NO. 284;RNA;Artificial Sequence> uggugugauggugaucaucugggccgu
<SEQ ID NO. 285;RNA;Artificial Sequence> aaacccgcaggauaguuuucuucccua
<SEQ ID NO. 286;RNA;Artificial Sequence> caaacuggaugaaauaaauuaaaaccc
<SEQ ID NO. 287;RNA;Artificial Sequence> agaaguccuuaacauuucccuacguga
<SEQ ID NO. 288;RNA;Artificial Sequence> cucugucccacuggguaaacccuggcc
<SEQ ID NO. 289;RNA;Artificial Sequence> cacaauaacaaauuuaaaccuugcucc
<SEQ ID NO. 290;RNA;Artificial Sequence> aaaugcauuugaacaacauaauacaca
<SEQ ID NO. 291;RNA;Artificial Sequence> ggcuuuccugucacaaagauuaaaaac
<SEQ ID NO. 292;RNA;Artificial Sequence> agggcuuuccugucacaaagauuaaaa
<SEQ ID NO. 293;RNA;Artificial Sequence> ggccaugcugggagacauaagcagcag
<SEQ ID NO. 294;RNA;Artificial Sequence> ucagggagaagcuucugaaacacuucu
<SEQ ID NO. 295;RNA;Artificial Sequence> aagggcuucuuccuuauugauggucag
<SEQ ID NO. 296;RNA;Artificial Sequence> ugaagggcuucuuccuuauugaugguc
<SEQ ID NO. 297;RNA;Artificial Sequence> cgcugaagggcuucuuccuuauugaug
<SEQ ID NO. 298;RNA;Artificial Sequence> gccgcugaagggcuucuuccuuauuga
<SEQ ID NO. 299;RNA;Artificial Sequence> acuggccgcugaagggcuucuuccuua
<SEQ ID NO. 300;RNA;Artificial Sequence> cggagcuuuucaccuuuaguuaugcuu
<SEQ ID NO. 301;RNA;Artificial Sequence> ccggagcuuuucaccuuuaguuaugcu
<SEQ ID NO. 302;RNA;Artificial Sequence> cagacuguugacuggcgugauguaguu
<SEQ ID NO. 303;RNA;Artificial Sequence> cuuuugaacucugcuuaaauccagugg
<SEQ ID NO. 304;RNA;Artificial Sequence> gcuuuugaacucugcuuaaauccagug
<SEQ ID NO. 305;RNA;Artificial Sequence> agggcuuuugaacucugcuuaaaucca
<SEQ ID NO. 306;RNA;Artificial Sequence> aagggcuuuugaacucugcuuaaaucc
<SEQ ID NO. 307;RNA;Artificial Sequence> ugaagggcuuuugaacucugcuuaaau
<SEQ ID NO. 308;RNA;Artificial Sequence> cugaagggcuuuugaacucugcuuaaa
<SEQ ID NO. 309;RNA;Artificial Sequence> cgcugaagggcuuuugaacucugcuua
<SEQ ID NO. 310;RNA;Artificial Sequence> cgagcggcuucacucagacccugaggc
<SEQ ID NO. 311;RNA;Artificial Sequence> uugacuggcgugauguaguugcuuggg
<SEQ ID NO. 312;RNA;Artificial Sequence> cacgcaccaagaagcugccauugaucc
<SEQ ID NO. 313;RNA;Artificial Sequence> cugaugaauccaaugugggcuggaauc
<SEQ ID NO. 314;RNA;Artificial Sequence> cuuagguauuccacauucucagcugug
<SEQ ID NO. 315;RNA;Artificial Sequence> ugagccucaaauuaggagauacguuuu
<SEQ ID NO. 316;RNA;Artificial Sequence> ccaauuguagagaaauuauuuuaggaa
<SEQ ID NO. 317;RNA;Artificial Sequence> ggcuccuaacuagcugaaucuuccaau
<SEQ ID NO. 318;RNA;Artificial Sequence> guggauauugacuaggagaguuuaaaa
<SEQ ID NO. 319;RNA;Artificial Sequence> ugugacugaacauaacuguaggcugaa
<SEQ ID NO. 320;RNA;Artificial Sequence> guaugugugugugacugaacauaacug
<SEQ ID NO. 321;RNA;Artifrcial Sequence> aagcaaaaggaacauuuuguaugugug
<SEQ ID NO. 322;RNA;Artificial Sequence> aaaaauuacuuuaaaagcaaaaggaac
<SEQ ID NO. 323;RNA;Artificial Sequence> ccauugacuguugcuucacaggucaga
<SEQ ID NO. 324;RNA;Artificial Sequence> auugguuugucgaugugugagauaguu
<SEQ ID NO. 325;RNA;Artificial Sequence> agugguagcaguacaauugaggacaag
<SEQ ID NO. 326;RNA;Artificial Sequence> uaagaccgcuugccagcuacgguuuca
<SEQ ID NO. 327;RNA;Artificial Sequence> agccgguaagaccgcuugccagcuacg
<SEQ ID NO. 328;RNA;Artifrcial Sequence> gguaacccaucuuuuaaccauacaacu
<SEQ ID NO. 329;RNA;Artificial Sequence> ucgcagguaacccaucuuuuaaccaua
<SEQ ID NO. 330;RNA;Artificial Sequence> cucagcaagauuguauaauucccugca
<SEQ ID NO. 331;RNA;Artificial Sequence> acuguuuuaugcucagcaagauuguau
<SEQ ID NO. 332;RNA;Artificial Sequence> aggauaaaggacucuucauuauuggaa
<SEQ ID NO. 333;RNA;Artificial Sequence> caacuugcguuggaacauccaaagugu
<SEQ ID NO. 334;RNA;Artificial Sequence> augguuucaguuuaguggaagcauuua
<SEQ ID NO. 335;RNA;Artificial Sequence> auauuuaacaaagucaaacuuucucac
<SEQ ID NO. 336;RNA;Artificial Sequence> aacuuuuaauauacaguaguucuuuuc
<SEQ ID NO. 337;RNA;Artificial Sequence> guuaagucaaaacccguauuucuaaag
<SEQ ID NO. 338;RNA;Artificial Sequence> gugcugaguuugcuguacccauguuga
<SEQ ID NO. 339;RNA;Artificial Sequence> ugaggucagcaucuucugugucuuuac
<SEQ ID NO. 340;RNA;Artificial Sequence> gcgaucugaauaaaccucccuacuagc
<SEQ ID NO. 341;RNA;Artificial Sequence> aucccagaacccugcugcagaaggcca
<SEQ ID NO. 342;RNA;Artificial Sequence> cauaauuuccaauauguaccagaccuu
<SEQ ID NO. 343;RNA;Artificial Sequence> cuagugcuuccaucggaaggacuaggu
<SEQ ID NO. 344;RNA;Artificial Sequence> uccacauaaaaacaauauucacuggga
<SEQ ID NO. 345;RNA;Artificial Sequence> ucuaccaauuccaacuugaauucauug
<SEQ ID NO. 346;RNA;Artificial Sequence> ucuccaagucuaaaucuguguccugag
<SEQ ID NO. 347;RNA;Artificial Sequence> uggaauacuguaacugugcuuugagga
<SEQ ID NO. 348;RNA;Artificial Sequence> uuaauucaucagugguggcagugguag
<SEQ ID NO. 349;RNA;Artificial Sequence> gugaugauguggcacuaguaguuucuu
<SEQ ID NO. 350;RNA;Artificial Sequence> ucuguuuggugaggcuguccgacuuug
<SEQ ID NO. 351;RNA;Artificial Sequence> ccaucauguuccauuuuucgcuuucuc
<SEQ ID NO. 352;RNA;Artificial Sequence> gcagucuacaugcuaaaucagagggua
741-3674

CA 02677068 2009-09-01
<SEQ ID NO. 353;RNA;Artificial Sequence> cauaaauagauccuuaaauagcucaaa
<SEQ ID NO. 354;RNA;Artificial Sequence> ugauaauagugcuuuuucaccuuuuuc
<SEQ ID NO. 355;RNA;Artificial Sequence> gcagaacugauaauagugcuuuuucac
<SEQ ID NO. 356;RNA;Artificial Sequence> guagguuuaaucuuucuuuucagccau
<SEQ ID NO. 357;RNA;Artificial Sequence> agaaggauuuuauuauaaggguuuaau
<SEQ ID NO. 358;RNA;Artificial Sequence> gucuacagcauuggcuaauaguaugaa
<SEQ ID NO. 359;RNA;Artificial Sequence> cuauuccuaucaaaaugcuucugucua
<SEQ ID NO. 360;RNA;Artificial Sequence> ucagggccauuaucuuauuugcucuau
<SEQ ID NO. 361;RNA;Artificial Sequence> ugcuugaggaagagaaaaauguugguc
<SEQ ID NO. 362;RNA;Artificial Sequence> ugggcugaacuuuucucauacuuaaag
<SEQ ID NO. 363;RNA;Artificial Sequence> gguucagcagccaucuuuauuccugcg
<SEQ ID NO.364;RNA;Artificial Sequence> ugaagagaacuuggucauucaaauuuc
<SEQ ID NO. 365;RNA;Artificial Sequence> cucuaggcuggcuaucuuuauacauac
<SEQ ID NO. 366;RNA;Artificial Sequence> acacuucacagagauaguuacagccau
<SEQ ID NO. 367;RNA;Artificial Sequence> uugaaauuuucucacacuucacagaga
<SEQ ID NO. 368;RNA;Artificial Sequence> ucaggaggauucauuuccuuaaaggaa
<SEQ ID NO.369;RNA;Artificial Sequence> auaugaugucacuuuuuguauccuuga
<SEQ ID NO. 370;RNA;Artificial Sequence> uaugaugaagauucaaauugcaucuua
<SEQ ID NO. 371;RNA;Artificial Sequence> uuaauagcuagucuucguuuugaacag
<SEQ ID NO. 372;RNA;Artificial Sequence> auuuuuaguagagaugagguuucacca
<SEQ ID NO.373;RNA;Artificial Sequence> aggcgagauagagcuucucuuucguuc
<SEQ ID NO. 374;RNA;Artificial Sequence> aacuggaccgaaggcgcuuguggagaa
<SEQ ID NO. 375;RNA;Artificial Sequence> gcggcuacaucuuuggaaucuucuccu
<SEQ ID NO. 376;RNA;Artificial Sequence> caagucuccucauugaauccagauugg
<SEQ ID NO. 377;RNA;Artificial Sequence> uccucacuacucucaaaucuguucugg
<SEQ ID NO. 378;RNA;Artificial Sequence> uuuguacucaucugcacagcucuggcu
<SEQ ID NO. 379;RNA;Artificial Sequence> gcccauuaacaacaacaaucugaggug
<SEQ ID NO. 380;RNA;Artificial Sequence> aauaaauuaaaaauaauuaaaauagug
<SEQ ID NO. 381;RNA;Artificial Sequence> cauauuuaaauauuaauaaauuaaaaa
<SEQ ID NO. 382;RNA;Artificial Sequence> gaaacaaaggauauucaaacugcauag
<SEQ ID NO. 383;RNA;Artificial Sequence> caaacacuuagacgccagcagcauggg
<SEQ ID NO.384;RNA;Artificial Sequence> uuugucacaggugaaaugcacaucuga
<SEQ ID NO.385;RNA;Artificial Sequence> uaauucagccuggcacagguuuugauc
<SEQ ID NO. 386;RNA;Artificial Sequence> auuguaagaaugacuacccacauucac
<SEQ ID NO. 387;RNA;Artificial Sequence> caauuguaagaaugacuacccacauuc
<SEQ ID NO.388;RNA;Artificial Sequence> guacacucucugaugcucauuuucaua
<SEQ ID NO. 389;RNA;Artificial Sequence> cugcugaguucuacaugaaaagcaaau
<SEQ ID NO. 390;RNA;Artificial Sequence> uacugaaaauaaauauagaaauacaac
<SEQ ID NO.391;RNA;Artificial Sequence> uuccauuuaagaaacauuaaucaaaac
<SEQ ID NO. 392;RNA;Artificial Sequence> acaauuuuaggcacuauacacguuguu
<SEQ ID NO. 393;RNA;Artificial Sequence> ccagauguuaguagccaaggauauggu
<SEQ ID NO. 394;RNA;Artificial Sequence> agcucacagucuccagauguuaguagc
<SEQ ID NO. 395;RNA;Artificial Sequence> auuaauaaaaagcacacaacuuauggc
<SEQ ID NO. 396;RNA;Artificial Sequence> aauguaagaagagccaaaaugaugcau
<SEQ ID NO. 397;RNA;Artificial Sequence> acauuuuuacaaauguaagaagagcca
<SEQ ID NO. 398;RNA;Artificial Sequence> aauaugaauuaagaugaccuaaucugu
<SEQ ID NO. 399;RNA;Artificial Sequence> ucaugauuaguucuuucaauuccaucc
<SEQ ID NO. 400;RNA;Artificial Sequence> cccaagagcagaaggaaugagugugca
<SEQ ID NO. 401;RNA;Artificial Sequence> cucaaagcuacugguuaccucuacacc
<SEQ ID NO. 402;RNA;Artificial Sequence> ugaaauauuacguggcaugugguuggg
<SEQ ID NO.403;RNA;Artificial Sequence> agugaagagaauaacuuguuuccgaag
<SEQ ID NO. 404;RNA;Artificial Sequence> uuucuuagcauuaguuauugggaguga
<SEQ ID NO. 405;RNA;Artificial Sequence> uugauuuucagcauuucuuagcauuag
<SEQ ID NO. 406;RNA;Artificial Sequence> aaaguaaucauauuuagagaaagacag
<SEQ ID NO.407;RNA;Artificial Sequence> uguagaacaaaaugccugaaauucagc
<SEQ ID NO.408;RNA;Artificial Sequence> gagagucccgggugagagggaaucgcc
<SEQ ID NO. 409;RNA;Artificial Sequence> cuuuacuuuaaagguucacuuuccuug
<SEQ ID NO. 410;RNA;Artificial Sequence> ccaggcuuccagagcaugcagccuccu
<SEQ ID NO.411;RNA;Artificial Sequence> cucucuuuuguuuucuguucagagaaa
<SEQ ID NO. 412;RNA;Artificial Sequence> cggcauaacugauuacagccaaguuca
<SEQ ID NO. 413;RNA;Artificial Sequence> uggacuucuuuuaauuuuggcuucuuc
<SEQ ID NO. 414;RNA;Artificial Sequence> uaaccucaccuggacuucuuuuaauuu
<SEQ ID NO.415;RNA;Artificial Sequence> guccucuucccgauaauccggauucag
<SEQ ID NO. 416;RNA;Artificial Sequence> acaauacuugcuuugaugucacauuaa
<SEQ ID NO. 417;RNA;Artificial Sequence> gagugcuacaauacuugcuuugauguc
<SEQ ID NO. 41 8;RNA;Artificial Sequence> auuugugguuuuguuuucucucucucu
<SEQ ID NO. 419;RNA;Artificial Sequence> uguaugggcuuaaauacuacagcgagg
<SEQ ID NO. 420;RNA;Artificial Sequence> cuguaugggcuuaaauacuacagcgag
<SEQ ID NO.42 I;RNA;Artificial Sequence> ggaagguuucuguaugggcuuaaauac
<SEQ ID NO. 422;RNA;Artificial Sequence> guagguauaccauguuuauuuuaauac
<SEQ ID NO. 423;RNA;Artificial Sequence> uccgaaaacuggccgaucagaacagcc
<SEQ ID NO. 424;RNA;Artificial Sequence> cccuguuccaaaguucaaauuauuugu
<SEQ ID NO. 425;RNA;Artificial Sequence> acuggaaaguuaaauuaaggucgcaau
741-3675

CA 02677068 2009-09-01
<SEQ ID NO. 426;RNA;Artificial Sequence> caaaaccaaacuuuagcuuucucagcc
<SEQ ID NO. 427;RNA;Artificial Sequence> uacagugggaaguagcaucuuuacuuu
<SEQ ID NO. 428;RNA;Artificial Sequence> ucauaugguaucagcaauuaagcagua
<SEQ ID NO. 429;RNA;Artificial Sequence> cagcccauguuucauucauaugguauc
<SEQ ID NO. 430;RNA;Artificial Sequence> uaugaaaaaguuggauaagaaaguugg
<SEQ ID NO. 431;RNA;Artificial Sequence> uccggccucaugaugucaugcaaggcu
<SEQ ID NO. 432;RNA;Artificial Sequence> acaaaugcagucauauacaaauucagg
<SEQ ID NO. 433;RNA;Artificial Sequence> gguaguaaacauucuacuaggauucuu
<SEQ ID NO.434;RNA;Artificial Sequence> uuucaucaaaaaauucuucccuuucug
<SEQ ID NO. 435;RNA;Artificial Sequence> aaauucacacacuggcaugccgauagc
<SEQ ID NO. 436;RNA;Artificial Sequence> acauacauugcucuacuaugaggugaa
<SEQ ID NO. 437;RNA;Artificial Sequence> uauauaugugcuuuggcaauucuggug
<SEQ ID NO.438;RNA;Artificial Sequence> ggagaaacuauuacccagaucaccacu
<SEQ ID NO. 439;RNA;Artificial Sequence> auuuggagaaacuauuacccagaucac
<SEQ ID NO. 440;RNA;Artificial Sequence> uuucuaggaaguauucaucacauccac
<SEQ ID NO. 441;RNA;Artificial Sequence> cauauaugguguagcuguggaaaugcg
<SEQ ID NO. 442;RNA;Artificial Sequence> cuccauucauauaugguguagcugugg
<SEQ ID NO. 443;RNA;Artificial Sequence> aucuucuucucguguaagaacugcagc
<SEQ ID NO. 444;RNA;Artificial Sequence> ucccuguaaaugaucuucuucucgugu
<SEQ ID NO. 445;RNA;Artificial Sequence> gucccuguaaaugaucuucuucucgug
<SEQ ID NO. 446;RNA;Artificial Sequence> ucaggucccuguaaaugaucuucuucu
<SEQ ID NO. 447;RNA;Artificial Sequence> gaugcagucaaacaccucuuccucugu
<SEQ ID NO. 448;RNA;Artificial Sequence> cgaugcagucaaacaccucuuccucug
<SEQ ID NO. 449;RNA;Artificial Sequence> cccugugaacucgcccucaaaguagcg
<SEQ ID NO. 450;RNA;Artificial Sequence> ggacagaggugccaggagaugcccuca
<SEQ ID NO. 45 1;RNA;Artificial Sequence> uuaaaaagacaaaccauaucacuccuu
<SEQ ID NO. 452;RNA;Artificial Sequence> cuuaaaaagacaaaccauaucacuccu
<SEQ ID NO. 453;RNA;Artificial Sequence> gacaaccuuuaggaucuuuacugcaac
<SEQ ID NO. 454;RNA;Artificial Sequence> gucgacaaccuuuaggaucuuuacugc
<SEQ ID NO. 455;RNA;Artificial Sequence> acaauugccagguuguccuuugucaug
<SEQ ID NO.456;RNA;Artificial Sequence> ccucgcaccacugggucacaauugcca
<SEQ ID NO. 457;RNA;Artificial Sequence> auuucaugucucuauggaugauguucu
<SEQ ID NO. 458;RNA;Artificial Sequence> uggagaaauauauuguuggauuucaug
<SEQ ID NO. 459;RNA;Artificial Sequence> agccuucauggagaaauauauuguugg
<SEQ ID NO. 460;RNA; Artificial Sequence> accacuccagcgugacuuuacuguugc
<SEQ ID NO. 461;RNA;Artificial Sequence> ccucucuuccuuuacuuucuucacaca
<SEQ ID NO.462;RNA;Artificial Sequence> gcccgaugcaaggauggcucggaagcg
<SEQ ID NO. 463;RNA;Artificial Sequence> cacaguaggauauucaaccuccauuuc
<SEQ ID NO. 464;RNA;Artificial Sequence> uuacacaguaggauauucaaccuccau
<SEQ ID NO. 465;RNA;Artificial Sequence> uacacuacaagggaaaacucaaaaucu
<SEQ ID NO. 466;RNA;Artificial Sequence> caaucaacaaagaacaaacaggauaaa
<SEQ ID NO. 467;RNA;Artificial Sequence> uuucaaucaacaaagaacaaacaggau
<SEQ ID NO. 468;RNA;Artificial Sequence> auggaagaaaaagaaggcuguagagaa
<SEQ ID NO. 469;RNA;Artificial Sequence> uagaaggaagauuagcuauggaagaaa
<SEQ ID NO. 470;RNA;Artificial Sequence> augaagcauucaacaggaagauuauuu
<SEQ ID NO. 471;RNA;Artificial Sequence> caugaagcauucaacaggaagauuauu
<SEQ ID NO. 472;RNA;Artificial Sequence> ucaaaguagaauucaagucaugaagca
<SEQ ID NO. 473;RNA;Artificial Sequence> gucuguaguugcuucucucccucuuag
<SEQ ID NO. 474;RNA;Artificial Sequence> guugaccuuggucugguaggagacggc
<SEQ ID NO. 475;RNA;Artificial Sequence> gucgagauagucgggccgauugaucuc
<SEQ ID NO. 476;RNA;Artificial Sequence> guuugggaagguuggauguucguccuc
<SEQ ID NO. 477;RNA;Artificial Sequence> aguucuaagcuuggguuccgacccuaa
<SEQ ID NO. 478;RNA;Artificial Sequence> uuaaaguucuaagcuuggguuccgacc
<SEQ ID NO.479;RNA;Artificial Sequence> guugcuuaaaguucuaagcuuggguuc
<SEQ ID NO. 480;RNA;Artificial Sequence> gugguggucuuguugcuuaaaguucua
<SEQ ID NO. 481;RNA;Artificial Sequence> acuuuauuucucgccacugaauaguag
<SEQ ID NO. 482;RNA;Artificial Sequence> aacuuuauuucucgccacugaauagua
<SEQ ID NO. 483;RNA;Artificial Sequence> ggaucauuuccuguuaucuguguuugu
<SEQ ID NO. 484;RNA;Artificial Sequence> guuucauuucuucucuuuucuuaaggc
<SEQ ID NO. 485;RNA;Artificial Sequence> ggaggauggaaacacacuccuucaguu
<SEQ ID NO. 486;RNA;Artificial Sequence> ucaaagauuuucagucccgcggugaca
<SEQ ID NO. 487;RNA;Artificial Sequence> ccugaacggcacgcuuauuucugcugu
<SEQ ID NO. 488;RNA;Artificial Sequence> cuucuggacccugaacggcacgcuuau
<SEQ ID NO.489;RNA;Artificial Sequence> caagcagucuugagugacuguuucuuc
<SEQ ID NO. 490;RNA;Artificial Sequence> ccaaagacauggaccuucuuccucuga
<SEQ ID NO. 491;RNA;Artificial Sequence> guguuucaggcauauuuugaauacauc
<SEQ ID NO. 492;RNA;Artificial Sequence> gagguacagagaaagggaggaaaauag
<SEQ ID NO. 493;RNA;Artificial Sequence> ucuugucuugcucuaucuuucuuuggu
<SEQ ID NO. 494;RNA;Artificial Sequence> uuucuugucuugcucuaucuuucuuug
<SEQ ID NO. 495;RNA;Artificial Sequence> ggaucuuguacaaacaaaugcuuucuc
<SEQ ID NO. 496;RNA;Artificial Sequence> ucugcaaguacguucguuuaacucaag
<SEQ ID NO. 497;RNA;Artificial Sequence> ucuguaucgaucguucuguaucagucu
<SEQ ID NO. 498;RNA;Artificial Sequence> auuuauuuuuauauauauauaauauau
741-3676

CA 02677068 2009-09-01
<SEQ ID NO. 499;RNA;Artificial Sequence> auauuuauuuuuauauauauauaauau
<SEQ ID NO. 500;RNA;Artificial Sequence> cacagcagucaaauacauccagugaag
<SEQ ID NO. 501;RNA;Artificial Sequence> gucucucaucuccuccucuucccuguc
<SEQ ID NO. 502;RNA;Artificial Sequence> ccaagugggacaaaaaaaagaucaugc
<SEQ ID NO. 503;RNA;Artificial Sequence> guauuuugaugagg
<SEQ ID NO. 504;RNA;Artificial Sequence> ggcccagaugau
<SEQ ID NO. 505;RNA;Artificial Sequence> gggaagaaaacuau
<SEQ ID NO. 506;RNA;Artificial Sequence> guuuuaauuuauuuc
<SEQ ID NO. 507;RNA;Artificial Sequence> acguagggaaau
<SEQ ID NO. 508;RNA;Artificial Sequence> ccaggguuuacc
<SEQ ID NO. 509;RNA;Artificial Sequence> agcaagguuua
<SEQ ID NO. 5 1 0;RNA;Artificial Sequence> uguauuauguug
<SEQ ID NO.511;RNA;Artificial Sequence> uuuuaaucuuuguga
<SEQ ID NO. 512;RNA;Artificial Sequence> uuaaucuuugugac
<SEQ ID NO. 513;RNA;Artificial Sequence> gcugcuuaugucu
<SEQ ID NO. 514;RNA;Artificial Sequence> aaguguuucagaag
<SEQ ID NO. 515;RNA; Artificial Sequence> gaccaucaauaag
<SEQ ID NO. 516;RNA;Artificial Sequence> ccaucaauaagga
<SEQ ID NO. 517;RNA;Artificial Sequence> ucaauaaggaagaa
<SEQ ID NO. 518;RNA;Artificial Sequence> aauaaggaagaagc
<SEQ ID NO. 519;RNA;Artificial Sequence> aggaagaagcccu
<SEQ ID NO. 520;RNA;Artificial Sequence> gcauaacuaaagg
<SEQ ID NO. 521;RNA;Artificial Sequence> cauaacuaaaggug
<SEQ ID NO. 522;RNA;Artificial Sequence> cuacaucacgcc
<SEQ ID NO. 523;RNA;Artificial Sequence> acuggauuuaag
<SEQ ID NO. 524;RNA;Artificial Sequence> cuggauuuaagc
<SEQ ID NO. 525;RNA; Artificial Sequence> gauuuaagcagag
<SEQ ID NO. 526;RNA;Artificial Sequence> auuuaagcagagu
<SEQ ID NO. 527;RNA;Artificial Sequence> uuaagcagaguuc
<SEQ ID NO. 528;RNA;Artificial Sequence> uaagcagaguuca
<SEQ ID NO. 529;RNA;Artificial Sequence> agcagaguucaaaa
<SEQ ID NO. 530;RNA;Artificial Sequence> cucagggucuga
<SEQ ID NO. 531;RNA;Artificial Sequence> caagcaacuacau
<SEQ ID NO. 532;RNA;Artificial Sequence> aucaauggcagc
<SEQ ID NO. 533;RNA;Artificial Sequence> uuccagcccac
<SEQ ID NO. 534;RNA;Artificial Sequence> cagcugagaaug
<SEQ ID NO. 535;RNA;Artificial Sequence> aacguaucuccua
<SEQ ID NO. 5 36;RNA; Artificial Sequence> ccuaaaauaauuuc
<SEQ ID NO. 537;RNA;Artificial Sequence> uggaagauucagc
<SEQ ID NO. 538;RNA;Artificial Sequence> uuaaacucuccu
<SEQ ID NO. 539;RNA;Artificial Sequence> cagccuacaguu
<SEQ ID NO. 540;RNA;Artificial Sequence> guuauguucaguc
<SEQ ID NO. 541;RNA;Artificial Sequence> cacauacaaaaug
<SEQ ID NO. 542;RNA;Artificial Sequence> uccuuuugc
<SEQ ID NO. 543;RNA;Artificial Sequence> ugaccugugaag
<SEQ ID NO. 544;RNA;Artificial Sequence> cuaucucacaca
<SEQ ID NO. 545;RNA;Artificial Sequence> uguccucaauugu
<SEQ ID NO. 546;RNA;Artificial Sequence> aaaccguagcug
<SEQ ID NO. 547;RNA;Artificial Sequence> uagcuggcaagc
<SEQ ID NO. 548;RNA;Artificial Sequence> uuguaugguuaaaa
<SEQ ID NO. 549;RNA;Artificial Sequence> ugguuaaaagaugg
<SEQ ID NO. 550;RNA;Artificial Sequence> cagggaauuauac
<SEQ ID NO. 551;RNA;Artificial Sequence> acaaucuugcug
<SEQ ID NO. 552;RNA;Artificial Sequence> ccaauaaugaaga
<SEQ ID NO. 553;RNA;Artificial Sequence> acuuuggauguuc
<SEQ ID NO. 554;RNA;Artificial Sequence> aaugcuuccacu
<SEQ ID NO. 555;RNA;Artificial Sequence> gagaaaguuug
<SEQ ID NO. 556;RNA;Artificial Sequence> aaagaacuacu
<SEQ ID NO. 557;RNA;Artificial Sequence> uuagaaauacgg
<SEQ ID NO. 558;RNA;Artificial Sequence> aacauggguaca
<SEQ ID NO. 559;RNA;Artificial Sequence> aaagacacagaaga
<SEQ ID NO. 560;RNA;Artificial Sequence> uaguagggagg
<SEQ ID NO. 561;RNA;Artificial Sequence> gccuucugcagc
<SEQ ID NO. 562;RNA;Artificial Sequence> ggucugguac
<SEQ ID NO. 563;RNA;Artificial Sequence> cuaguccuuccg
<SEQ ID NO. 564;RNA;Artificial Sequence> ccagugaauauu
<SEQ ID NO. 565;RNA;Artificial Sequence> augaauucaaguu
<SEQ ID NO. 566;RNA;Artificial Sequence> caggacacagau
<SEQ ID NO. 567;RNA;Artificial Sequence> cucaaagcacag
<SEQ ID NO. 568;RNA; Artificial Sequence> accacugcca
<SEQ ID NO. 569;RNA;Artificial Sequence> gaaacuacuagug
<SEQ ID NO. 570;RNA;Artificial Sequence> aagucggacagc
<SEQ ID NO.571;RNA;Artificial Sequence> gaaagcgaaaaau
741-3677

CA 02677068 2009-09-01
<SEQ ID NO. 572;RNA;Artificial Sequence> cccucugauuuag
<SEQ ID NO. 573;RNA;Artificial Sequence> ugagcuauuuaa
<SEQ ID NO. 574;RNA;Artificial Sequence> aaaaggugaaaaa
<SEQ ID NO. 575;RNA;Artificial Sequence> gaaaaagcacuauu
<SEQ ID NO. 576;RNA;Artificial Sequence> ggcugaaaagaa
<SEQ ID NO. 577;RNA;Artificial Sequence> uaaacccuuaua
<SEQ ID NO.578;RNA;Artificial Sequence> cauacuauuagcc
<SEQ ID NO. 579;RNA;Artificial Sequence> gacagaagcauu
<SEQ ID NO. 580;RNA;Artificial Sequence> agagcaaauaagau
<SEQ ID NO. 581;RNA;Artificial Sequence> ccaacauuuuucuc
<SEQ ID NO. 582;RNA;Artificial Sequence> uuaaguaugagaaaa
<SEQ ID NO. 583;RNA;Artificial Sequence> caggaauaaagaug
<SEQ ID NO. 584;RNA;Artificial Sequence> aauuugaaugacc
<SEQ ID NO. 585;RNA;Artificial Sequence> auguauaaagauag
<SEQ ID NO. 586;RNA;Artificial Sequence> ggcuguaacuau
<SEQ ID NO. 587;RNA;Artificial Sequence> ucugugaagug
<SEQ ID NO. 588;RNA;Artificial Sequence> ccuuuaaggaaaug
<SEQ ID NO. 589;RNA;Artificial Sequence> aaggauacaaaaa
<SEQ ID NO. 590;RNA;Artificial Sequence> agaugcaauuug
<SEQ ID NO. 591;RNA;Artificial Sequence> guucaaaacgaa
<SEQ ID NO. 592;RNA;Artificial Sequence> gugaaaccuca
<SEQ ID NO. 593;RNA;Artificial Sequence> acgaaagagaagc
<SEQ ID NO. 594;RNA;Artificial Sequence> cuccacaagcgc
<SEQ ID NO. 595;RNA;Artificial Sequence> gagaagauuccaaa
<SEQ ID NO. 596;RNA;Artificial Sequence> aaucuggauucaa
<SEQ ID NO. 597;RNA;Artificial Sequence> agaacagauuuga
<SEQ ID NO. 598;RNA;Artificial Sequence> ccagagcugug
<SEQ ID NO. 599;RNA;Artificial Sequence> ccucagauuguu
<SEQ ID NO. 600;RNA;Artificial Sequence> cuauuuuaauua
<SEQ ID NO. 601;RNA;Artificial Sequence> uuuaauuuauuaa
<SEQ ID NO. 602;RNA;Artificial Sequence> augcaguuugaa
<SEQ ID NO. 603;RNA;Artificial Sequence> caugcugcugg
<SEQ ID NO. 604;RNA;Artificial Sequence> agaugugcauuuc
<SEQ ID NO. 605;RNA;Artificial Sequence> ucaaaaccugug
<SEQ ID NO. 606;RNA;Artificial Sequence> gaaugugggua
<SEQ ID NO. 607;RNA;Artificial Sequence> auguggguag
<SEQ ID NO.608;RNA;Artificial Sequence> ugaaaaugagcau
<SEQ ID NO. 609;RNA;Artificial Sequence> uugcuuuucaugu
<SEQ ID NO. 610;RNA;Artificial Sequence> uguauuucuaua
<SEQ ID NO. 611;RNA;Artificial Sequence> uuugauuaauguu
<SEQ ID NO. 612;RNA;Artificial Sequence> caacguguauag
<SEQ ID NO. 613;RNA;Artificial Sequence> cauauccuuggc
<SEQ ID NO. 614;RNA;Artificial Sequence> uacuaacaucugg
<SEQ ID NO. 615;RNA;Artificial Sequence> cauaaguugug
<SEQ ID NO. 616;RNA;Artificial Sequence> gcaucauuuugg
<SEQ ID NO.617;RNA;Artificial Sequence> gcucuucuua
<SEQ ID NO. 618;RNA;Artificial Sequence> agauuagguc
<SEQ ID NO. 619;RNA;Artificial Sequence> auggaauugaaa
<SEQ ID NO. 620;RNA;Artificial Sequence> cacacucauuccu
<SEQ ID NO. 621;RNA;Artificial Sequence> uguagagguaac
<SEQ ID NO. 622;RNA;Artificial Sequence> caaccacaugc
<SEQ ID NO. 623;RNA;Artificial Sequence> ucggaaacaagu
<SEQ ID NO. 624;RNA;Artificial Sequence> acucccaauaa
<SEQ ID NO. 625;RNA;Artificial Sequence> aaugcuaagaaau
<SEQ ID NO. 626;RNA;Artificial Sequence> gucuuucucua
<SEQ ID NO. 627;RNA; Artificial Sequence> ugaauuucagg
<SEQ ID NO.628;RNA;Artificial Sequence> cgauucccucuca
<SEQ ID NO. 629;RNA;Artificial Sequence> aggaaagugaa
<SEQ ID NO. 630;RNA;Artificial Sequence> gaggcugcaugc
<SEQ ID NO. 631;RNA;Artificial Sequence> ucucugaacag
<SEQ ID NO. 632;RNA;Artificial Sequence> aacuuggcugua
<SEQ ID NO. 633;RNA;Artificial Sequence> agaagccaaaau
<SEQ ID NO. 634;RNA;Artificial Sequence> auuaaaagaagucc
<SEQ ID NO. 635;RNA;Artificial Sequence> gaauccggauuauc
<SEQ ID NO. 636;RNA;Artificial Sequence> aaugugacauca
<SEQ ID NO. 637;RNA;Artificial Sequence> caucaaagcaagu
<SEQ ID NO.638;RNA;Artificial Sequence> agagagagaaa
<SEQ ID NO.639;RNA;Artificial Sequence> ucgcuguaguauu
<SEQ ID NO. 640;RNA;Artificial Sequence> cgcuguaguauuua
<SEQ ID NO. 641;RNA;Artificial Sequence> auuuaagcccaua
<SEQ ID NO. 642;RNA;Artificial Sequence> auuaaaauaaacaug
<SEQ ID NO. 643;RNA;Artificial Sequence> cuguucugaucg
<SEQ ID NO. 644;RNA;Artificial Sequence> aaauaauuugaacuuu
741-3678

CA 02677068 2009-09-01
<SEQ ID NO. 645;RNA;Artificial Sequence> ugcgaccuuaau
<SEQ ID NO. 646;RNA;Artificial Sequence> cugagaaagcu
<SEQ ID NO. 647;RNA;Artificial Sequence> aguaaagaugcua
<SEQ ID NO.648;RNA;Artificial Sequence> cugcuuaauugc
<SEQ ID NO. 649;RNA;Artificial Sequence> uaccauaugaauga
<SEQ ID NO. 650;RNA;Artificial Sequence> aacuuucuuauc
<SEQ ID NO. 651;RNA;Artificial Sequence> ccuugcaugacau
<SEQ ID NO. 652;RNA;Artificial Sequence> ugaauuuguauaug
<SEQ ID NO. 653;RNA;Artificial Sequence> gaauccuaguag
<SEQ ID NO. 654;RNA;Artificial Sequence> gaaagggaag
<SEQ ID NO. 655;RNA;Artificial Sequence> uaucggcaugc
<SEQ ID NO.656;RNA;Artificial Sequence> caccucauagua
<SEQ ID NO. 657;RNA;Artificial Sequence> ccagaauugcc
<SEQ ID NO.658;RNA;Artificial Sequence> uggugaucugg
<SEQ ID NO. 659;RNA;Artificial Sequence> gaucuggguaau
<SEQ ID NO. 660;RNA;Artificial Sequence> ggaugugaugaa
<SEQ ID NO. 661;RNA;Artificial Sequence> cauuuccacagc
<SEQ ID NO. 662;RNA;Artificial Sequence> acagcuacacc
<SEQ ID NO. 663;RNA;Artificial Sequence> ugcaguucuuac
<SEQ ID NO. 664;RNA;Artificial Sequence> acgagaagaaga
<SEQ ID NO. 665;RNA;Artificial Sequence> cgagaagaagau
<SEQ ID NO.666;RNA;Artificial Sequence> aagaagaucauuuac
<SEQ ID NO. 667;RNA;Artificial Sequence> agaggaagagg
<SEQ ID NO. 668;RNA;Artificial Sequence> gaggaagaggug
<SEQ ID NO. 669;RNA;Artificial Sequence> cuacuuugagggc
<SEQ ID NO. 670;RNA;Artificial Sequence> agggcaucuccu
<SEQ ID NO. 671;RNA;Artificial Sequence> ggagugauau
<SEQ ID NO. 672;RNA;Artificial Sequence> gagugauaugg
<SEQ ID NO. 673;RNA;Artificial Sequence> ugcaguaaagau
<SEQ ID NO. 674;RNA;Artificial Sequence> aguaaagauccua
<SEQ ID NO. 675;RNA;Artificial Sequence> ugacaaaggaca
<SEQ ID NO.676;RNA;Artificial Sequence> gcaauugugaccc
<SEQ ID NO. 677;RNA;Artificial Sequence> aacaucauccau
<SEQ ID NO. 678;RNA;Artificial Sequence> ugaaauccaaca
<SEQ ID NO. 679;RNA;Artificial Sequence> aacaauauauuucuc
<SEQ ID NO.680;RNA;Artificial Sequence> aacaguaaagucac
<SEQ ID NO. 681;RNA;Artificial Sequence> ugugaagaaaguaa
<SEQ ID NO.682;RNA;Artificial Sequence> cuuccgagccauc
<SEQ ID NO. 683;RNA;Artificial Sequence> aauggagguuga
<SEQ ID NO. 684;RNA;Artificial Sequence> ggagguugaaua
<SEQ ID NO.685;RNA;Artificial Sequence> auuuugaguuuuc
<SEQ ID NO.686;RNA;Artificial Sequence> uauccuguuugu
<SEQ ID NO.687;RNA;Artificial Sequence> ccuguuuguuc
<SEQ ID NO. 688;RNA;Artificial Sequence> cucuacagcc
<SEQ ID NO. 689;RNA;Artificial Sequence> ucuuccauagcu
<SEQ ID NO. 690;RNA;Artificial Sequence> auaaucuuccug
<SEQ ID NO. 691;RNA;Artificial Sequence> uaaucuuccugu
<SEQ ID NO. 692;RNA;Artificial Sequence> cuucaugacuug
<SEQ ID NO. 693;RNA;Artificial Sequence> aagagggagaga
<SEQ ID NO. 694;RNA;Artificial Sequence> cgucuccuacca
<SEQ ID NO. 695;RNA;Artificial Sequence> gaucaaucggcc
<SEQ ID NO.696;RNA;Artificial Sequence> ggacgaacaucc
<SEQ ID NO. 697;RNA;Artificial Sequence> agggucggaac
<SEQ ID NO. 698;RNA;Artificial Sequence> ucggaaccca
<SEQ ID NO. 699;RNA;Artificial Sequence> acccaagcuua
<SEQ ID NO. 700;RNA;Artificial Sequence> gaacuuuaagcaac
<SEQ ID NO. 701;RNA;Artificial Sequence> acuauucagug
<SEQ ID NO. 702;RNA;Artificial Sequence> cuauucagugg
<SEQ ID NO. 703;RNA;Artificial Sequence> aaacacagauaac
<SEQ ID NO. 704;RNA;Artificial Sequence> cuuaagaaaaga
<SEQ ID NO. 705;RNA;Artificial Sequence> cugaaggagugu
<SEQ ID NO. 706;RNA;Artitcial Sequence> ucaccgcggg
<SEQ ID NO. 707;RNA;Artificial Sequence> agcagaaauaagcg
<SEQ ID NO. 708;RNA;Artificial Sequence> aagcgugccguu
<SEQ ID NO. 709;RNA;Artificial Sequence> agaaacagucac
<SEQ ID NO. 710;RNA;Artificial Sequence> agaggaagaagg
<SEQ ID NO. 711 ;RNA;Artificial Sequence> uguauucaaaauau
<SEQ ID NO. 712;RNA;Artificial Sequence> auuuuccucccuu
<SEQ ID NO. 713;RNA;Artificial Sequence> caaagaaagauag
<SEQ ID NO. 714;RNA;Artificial Sequence> aagaaagauaga
<SEQ ID NO.715;RNA;Artificial Sequence> gaaagcauuuguu
<SEQ ID NO. 716;RNA;Artificial Sequence> ugaguuaaacgaa
<SEQ ID NO. 717;RNA;Artificial Sequence> acugauacagaa
741-3679

CA 02677068 2009-09-01
<SEQ ID NO. 718;RNA;Artificial Sequence> auauuauauaua
<SEQ ID NO. 719;RNA;Artificial Sequence> auuauauauaua
<SEQ ID NO. 720;RNA;Artificial Sequence> ucacuggaugua
<SEQ ID NO. 721;RNA;Artificial Sequence> cagggaagagga
<SEQ ID NO. 722;RNA; Artificial Sequence> augaucuuuuuuuug
<SEQ ID NO. 723;RNA;Artificial Sequence> aguucacggcc
<SEQ ID NO. 724;RNA;Artificial Sequence> caccaucacacca
<SEQ ID NO. 725;RNA;Artificial Sequence> ccugcggguuu
<SEQ ID NO. 726;RNA;Artificial Sequence> auccaguuug
<SEQ ID NO. 727;RNA;Artificial Sequence> guuaaggacuucu
<SEQ ID NO.728;RNA;Artificial Sequence> cagugggacagag
<SEQ ID NO. 729;RNA;Artificial Sequence> aauuuguuauugug
<SEQ ID NO. 730;RNA;Artificial Sequence> uucaaaugcauuu
<SEQ ID NO. 731;RNA;Artificial Sequence> caggaaagcc
<SEQ ID NO. 732;RNA;Artificial Sequence> aggaaagcccu
<SEQ ID NO. 733;RNA;Artificial Sequence> cccagcauggcc
<SEQ ID NO. 734;RNA;Artificial Sequence> cuucucccuga
<SEQ ID NO. 735;RNA;Artificial Sequence> gaagaagcccuu
<SEQ ID NO. 736;RNA;Artificial Sequence> agaagcccuuca
<SEQ ID NO. 737;RNA;Artificial Sequence> gcccuucagcg
<SEQ ID NO. 738;RNA;Artificial Sequence> ccuucagcggc
<SEQ ID NO. 739;RNA;Artificial Sequence> ucagcggccagu
<SEQ ID NO. 740;RNA;Artificial Sequence> ugaaaagcuccg
<SEQ ID NO. 741;RNA;Artificial Sequence> aaaagcuccgg
<SEQ ID NO. 742;RNA;Artificial Sequence> agucaacagucug
<SEQ ID NO. 743;RNA;Artificial Sequence> cagaguucaaaag
<SEQ ID NO. 744;RNA;Artificial Sequence> agaguucaaaagc
<SEQ ID NO. 745;RNA;Artificial Sequence> uucaaaagcccu
<SEQ ID NO. 746;RNA;Artificial Sequence> ucaaaagcccuu
<SEQ ID NO. 747;RNA;Artificial Sequence> aaaagcccuuca
<SEQ ID NO. 748;RNA;Artificial Sequence> aaagcccuucag
<SEQ ID NO. 749;RNA;Artificial Sequence> gugaagccgcucg
<SEQ ID NO. 750;RNA;Artificial Sequence> cacgccagucaa
<SEQ ID NO.751;RNA;Artificial Sequence> uucuuggugcgug
<SEQ ID NO. 752;RNA;Artificial Sequence> auuggauucaucag
<SEQ ID NO. 753;RNA;Artificial Sequence> uggaauaccuaag
<SEQ ID NO. 754;RNA; Artificial Sequence> auuugaggcuca
<SEQ ID NO. 755;RNA;Artificial Sequence> ucuacaauugg
<SEQ ID NO. 756;RNA;Artificial Sequence> uaguuaggagcc
<SEQ ID NO. 757;RNA;Artificial Sequence> agucaauauccac
<SEQ ID NO. 758;RNA;Artificial Sequence> auguucagucaca
<SEQ ID NO. 759;RNA;Artificial Sequence> acacacacauac
<SEQ ID NO. 760;RNA;Artificial Sequence> uuccuuuugcuu
<SEQ ID NO. 761;RNA;Artificial Sequence> uuuuaaaguaauuuuu
<SEQ ID NO. 762;RNA;Artificial Sequence> caacagucaaugg
<SEQ ID NO. 763;RNA;Artificial Sequence> ucgacaaaccaau
<SEQ ID NO. 764;RNA;Artificial Sequence> acugcuaccacu
<SEQ ID NO. 765;RNA;Artificial Sequence> gcaagcggucuua
<SEQ ID NO. 766;RNA;Artificial Sequence> ggucuuaccggcu
<SEQ ID NO. 767;RNA;Artificial Sequence> gauggguuacc
<SEQ ID NO. 768;RNA;Artificial Sequence> guuaccugcga
<SEQ ID NO. 769;RNA;Artificial Sequence> aaucuugcugag
<SEQ ID NO. 770;RNA;Artificial Sequence> agcauaaaacagu
<SEQ ID NO. 771;RNA;Artificial Sequence> guccuuuauccu
<SEQ ID NO.772;RNA;Artificial Sequence> caacgcaaguug
<SEQ ID NO. 773;RNA; Artificial Sequence> aaacugaaaccau
<SEQ ID NO. 774;RNA;Artificial Sequence> acuuuguuaaauau
<SEQ ID NO. 775;RNA;Artificial Sequence> guauauuaaaaguu
<SEQ ID NO. 776;RNA;Artificial Sequence> guuuugacuuaac
<SEQ ID NO. 777;RNA;Artificial Sequence> gcaaacucagcac
<SEQ ID NO. 778;RNA;Artificial Sequence> ugcugaccuca
<SEQ ID NO. 779;RNA;Artificial Sequence> uuuauucagaucgc
<SEQ ID NO. 780;RNA;Artificial Sequence> aggguucugggau
<SEQ ID NO. 781;RNA;Artificial Sequence> auauuggaaauuaug
<SEQ ID NO. 782;RNA;Artificial Sequence> auggaagcacuag
<SEQ ID NO. 783;RNA;Artificial Sequence> guuuuuaugugga
<SEQ ID NO. 784;RNA;Artificial Sequence> ggaauugguaga
<SEQ ID NO.785;RNA;Artificial Sequence> uuagacuuggaga
<SEQ ID NO. 786;RNA;Artificial Sequence> uuacaguauucca
<SEQ ID NO. 787;RNA;Artificial Sequence> ccacugaugaauuaa
<SEQ ID NO. 788;RNA;Artificial Sequence> ccacaucaucac
<SEQ ID NO. 789;RNA;Artificial Sequence> cucaccaaacaga
<SEQ ID NO. 790;RNA;Artificial Sequence> ggaacaugaugg
741-3680

CA 02677068 2009-09-01
<SEQ ID NO. 791;RNA;Artificial Sequence> cauguagacugc
<SEQ ID NO. 792;RNA;Artificial Sequence> ggaucuauuuaug
<SEQ ID NO. 793;RNA;Artificial Sequence> gcacuauuauca
<SEQ ID NO. 794;RNA;Artificial Sequence> aucaguucugc
<SEQ ID NO. 795;RNA;Artificial Sequence> agauuaaaccuac
<SEQ ID NO. 796;RNA;Artificial Sequence> auaaaauccuucu
<SEQ ID NO. 797;RNA;Artificial Sequence> aaugcuguagac
<SEQ ID NO. 798;RNA;Artificial Sequence> uugauaggaauag
<SEQ ID NO. 799;RNA;Artificial Sequence> aauggcccuga
<SEQ ID NO. 800;RNA;Artificial Sequence> uuccucaagca
<SEQ ID NO. 801;RNA;Artificial Sequence> guucagccca
<SEQ ID NO.802;RNA;Artificial Sequence> gcugcugaacc
<SEQ ID NO. 803;RNA;Artificial Sequence> aaguucucuuca
<SEQ ID NO. 804;RNA;Artificial Sequence> ccagccuagag
<SEQ ID NO. 805;RNA;Artificial Sequence> cucugugaagugu
<SEQ ID NO. 806;RNA;Artificial Sequence> ugagaaaauuucaa
<SEQ ID NO. 807;RNA;Artificial Sequence> aauccuccuga
<SEQ ID NO. 808;RNA;Artificial Sequence> gugacaucauau
<SEQ ID NO. 809;RNA;Artificial Sequence> aaucuucaucaua
<SEQ ID NO. 810;RNA;Artificial Sequence> gacuagcuauuaa
<SEQ ID NO. 81 1;RNA;Artificial Sequence> ucucuacuaaaaau
<SEQ ID NO. 812;RNA;Artificial Sequence> ucuaucucgccu
<SEQ ID NO. 813;RNA;Artificial Sequence> cuucgguccaguu
<SEQ ID NO. 814;RNA;Artificial Sequence> gauguagccgc
<SEQ ID NO. 815;RNA;Artificial Sequence> ugaggagacuug
<SEQ ID NO.816;RNA;Artificial Sequence> gaguagugagga
<SEQ ID NO. 817;RNA;Artificial Sequence> cagaugaguacaaa
<SEQ ID NO. 818;RNA;Artificial Sequence> guuguuaaugggc
<SEQ ID NO. 819;RNA;Artificial Sequence> uuuuuaauuuauu
<SEQ ID NO. 820;RNA;Artificial Sequence> uauuuaaauaug
<SEQ ID NO.821;RNA;Artificial Sequence> uauccuuuguuuc
<SEQ ID NO. 822;RNA;Artificial Sequence> cgucuaaguguuug
<SEQ ID NO. 823;RNA;Artificial Sequence> accugugacaaa
<SEQ ID NO. 824;RNA;Artificial Sequence> ccaggcugaauua
<SEQ ID NO. 825;RNA;Artificial Sequence> gucauucuuacaau
<SEQ ID NO. 826;RNA;Artificial Sequence> ucauucuuacaauug
<SEQ ID NO. 827;RNA;Artificial Sequence> cagagaguguac
<SEQ ID NO. 828;RNA;Artificial Sequence> agaacucagcag
<SEQ ID NO. 829; RNA; Artificial Sequence> uuuauuuucagua
<SEQ ID NO. 830;RNA;Artificial Sequence> ucuuaaauggaa
<SEQ ID NO. 831;RNA;Artificial Sequence> ugecuaaaauugu
<SEQ ID NO. 832;RNA; Artificial Sequence> agacugugagcu
<SEQ ID NO. 833;RNA;Artificial Sequence> ugcuuuuuauuaau
<SEQ ID NO. 834;RNA;Artificial Sequence> cucuucuuacauu
<SEQ ID NO. 835;RNA;Artificial Sequence> cauuuguaaaaaugu
<SEQ ID NO. 836;RNA;Artificial Sequence> aucuuaauucauauu
<SEQ ID NO. 837;RNA;Artificial Sequence> gaacuaaucauga
<SEQ ID NO. 838;RNA;Artificial Sequence> ucugcucuuggg
<SEQ ID NO. 839;RNA;Artificial Sequence> caguagcuuugag
<SEQ ID NO. 840; RNA; Artificial Sequence> cacguaauauuuca
<SEQ ID NO. 841;RNA;Artificial Sequence> uauucucuucacu
<SEQ ID NO. 842;RNA;Artificial Sequence> cuaaugcuaagaaa
<SEQ ID NO. 843;RNA;Artificial Sequence> gcugaaaaucaa
<SEQ ID NO. 844;RNA;Artificial Sequence> aauaugauuacuuu
<SEQ ID NO. 845;RNA;Artificial Sequence> cauuuuguucuaca
<SEQ ID NO. 846;RNA;Artificial Sequence> cccgggacucuc
<SEQ ID NO. 847;RNA;Artificial Sequence> ccuuuaaaguaaag
<SEQ ID NO. 848;RNA;Artificial Sequence> ucuggaagccugg
<SEQ ID NO. 849;RNA;Artificial Sequence> aaaacaaaagagag
<SEQ ID NO. 850;RNA;Artificial Sequence> aucaguuaugccg
<SEQ ID NO. 851;RNA;Artificial Sequence> uaaaagaagucca
<SEQ ID NO. 852;RNA;Artificial Sequence> aggugagguua
<SEQ ID NO. 853;RNA;Artificial Sequence> gggaagaggac
<SEQ ID NO. 854;RNA;Artificial Sequence> aagcaaguauugu
<SEQ ID NO. 855;RNA;Artificial Sequence> auuguagcacuc
<SEQ ID NO. 856;RNA;Artificial Sequence> acaaaaccacaaau
<SEQ ID NO. 857;RNA;Artificial Sequence> uaagcccauaca
<SEQ ID NO. 858;RNA;Artificial Sequence> agcccauacag
<SEQ ID NO. 859;RNA;Artificial Sequence> cagaaaccuucc
<SEQ ID NO. 860;RNA;Artificial Sequence> guauaccuac
<SEQ ID NO. 861;RNA;Artificial Sequence> gccaguuuucgga
<SEQ ID NO. 862;RNA;Artificial Sequence> ggaacaggg
<SEQ ID NO. 863;RNA;Artificial Sequence> uuaacuuuccagu
741-3681

CA 02677068 2009-09-01
<SEQ ID NO. 864;RNA;Artificial Sequence> aaaguuugguuuug
<SEQ ID NO. 865;RNA;Artificial Sequence> cuucccacugua
<SEQ ID NO. 866;RNA;Artificial Sequence> ugauaccauauga
<SEQ ID NO. 867;RNA;Artificial Sequence> aacaugggcug
<SEQ ID NO. 868;RNA;Artificial Sequence> caacuuuuucaua
<SEQ ID NO. 869;RNA;Artificial Sequence> caugaggccgga
<SEQ ID NO. 870;RNA;Artificial Sequence> acugcauuugu
<SEQ ID NO. 871;RNA;Artificial Sequence> aauguuuacuacc
<SEQ ID NO. 872;RNA;Artificial Sequence> aauuuuuugaugaaa
<SEQ ID NO. 873;RNA;Artificial Sequence> cagugugugaauuu
<SEQ ID NO. 874;RNA;Artificial Sequence> gagcaauguaugu
<SEQ ID NO. 875;RNA;Artificial Sequence> aaagcacauauaua
<SEQ ID NO. 876;RNA;Artificial Sequence> guaauaguuucucc
<SEQ ID NO. 877;RNA;Artificial Sequence> aguuucuccaaau
<SEQ ID NO. 878;RNA;Artificial Sequence> uacuuccuagaaa
<SEQ ID NO. 879;RNA;Artificial Sequence> uacaccauauaug
<SEQ ID NO. 880;RNA;Artificial Sequence> auauaugaauggag
<SEQ ID NO. 881;RNA;Artificial Sequence> acgagaagaagau
<SEQ ID NO. 882;RNA;Artificial Sequence> ucauuuacaggga
<SEQ ID NO. 883;RNA;Artificial Sequence> cauuuacagggac
<SEQ ID NO. 884;RNA;Artificial Sequence> agggaccuga
<SEQ ID NO. 885;RNA;Artificial Sequence> uguuugacugcauc
<SEQ ID NO. 886;RNA;Artificial Sequence> uuugacugcaucg
<SEQ ID NO. 887;RNA;Artificial Sequence> gaguucacaggg
<SEQ ID NO. 888;RNA;Artificial Sequence> ggcaccucugucc
<SEQ ID NO. 889;RNA;Artificial Sequence> gguuugucuuuuuaa
<SEQ ID NO. 890;RNA;Artificial Sequence> uuugucuuuuuaag
<SEQ ID NO. 891;RNA;Artificial Sequence> ccuaaagguuguc
<SEQ ID NO. 892;RNA;Artificial Sequence> aagguugucgac
<SEQ ID NO. 893;RNA;Artificial Sequence> accuggcaauugu
<SEQ ID NO. 894;RNA;Artificial Sequence> aguggugcgagg
<SEQ ID NO. 895;RNA;Artificial Sequence> agagacaugaaau
<SEQ ID NO. 896;RNA;Artificial Sequence> auauauuucucca
<SEQ ID NO. 897;RNA;Artificial Sequence> caugaaggcu
<SEQ ID NO. 898;RNA;Artificial Sequence> gcuggaguggu
<SEQ ID NO. 899;RNA;Artificial Sequence> aggaagagagg
<SEQ ID NO. 900;RNA;Artificial Sequence> cuugcaucgggc
<SEQ ID NO. 901;RNA;Artificial Sequence> auauccuacugug
<SEQ ID NO. 902;RNA;Artificial Sequence> uccuacuguguaa
<SEQ ID NO. 903;RNA;Artificial Sequence> ccuuguagugua
<SEQ ID NO. 904;RNA;Artificial Sequence> ucuuuguugauug
<SEQ ID NO. 905;RNA;Artificial Sequence> uuuguugauugaaa
<SEQ ID NO. 906;RNA;Artificial Sequence> uucuuuuucuuccau
<SEQ ID NO. 907;RNA;Artificial Sequence> aaucuuccuucua
<SEQ ID NO. 908;RNA;Artificial Sequence> uugaaugcuucau
<SEQ ID NO. 909;RNA;Artificial Sequence> ugaaugcuucaug
<SEQ ID NO. 910;RNA;Artificial Sequence> aauucuacuuuga
<SEQ ID NO. 911 ;RNA;Artificial Sequence> agcaacuacagac
<SEQ ID NO. 912;RNA;Artificial Sequence> gaccaaggucaac
<SEQ ID NO. 913;RNA;Artificial Sequence> cgacuaucucgac
<SEQ ID NO. 914;RNA;Artificial Sequence> aaccuucccaaac
<SEQ ID NO. 915;RNA;Artificial Sequence> ccaagcuuagaacu
<SEQ ID NO. 916;RNA;Artificial Sequence> agcuuagaacuuuaa
<SEQ ID NO. 917;RNA;Artificial Sequence> aagaccaccac
<SEQ ID NO. 918;RNA;Artificial Sequence> gcgagaaauaaagu
<SEQ ID NO. 919;RNA;Artificial Sequence> cgagaaauaaaguu
<SEQ ID NO. 920;RNA;Artificial Sequence> aggaaaugaucc
<SEQ ID NO. 921;RNA;Artificial Sequence> gaagaaaugaaac
<SEQ ID NO. 922;RNA;Artificial Sequence> guuuccauccucc
<SEQ ID NO. 923;RNA;Artificial Sequence> acugaaaaucuuuga
<SEQ ID NO. 924;RNA; Artificial Sequence> ugccguucagg
<SEQ ID NO. 925;RNA;Artificial Sequence> caggguccagaag
<SEQ ID NO. 926;RNA;Artificial Sequence> ucaagacugcuug
<SEQ ID NO. 927;RNA;Artificial Sequence> uccaugucuuugg
<SEQ ID NO. 928;RNA;Artificial Sequence> gccugaaacac
<SEQ ID NO. 929;RNA;Artificial Sequence> ucucuguaccuc
<SEQ ID NO. 930;RNA;Artificial Sequence> agcaagacaaga
<SEQ ID NO. 931;RNA;Artificial Sequence> gcaagacaagaaa
<SEQ ID NO. 932;RNA;Artificial Sequence> uguacaagaucc
<SEQ ID NO. 933;RNA;Artificial Sequence> cguacuugcaga
<SEQ ID NO. 934;RNA;Artificial Sequence> cgaucgauacaga
<SEQ ID NO. 935;RNA;Artificial Sequence> uauaaaaauaaau
<SEQ ID NO. 936;RNA;Artificial Sequence> uaaaaauaaauau
741-3682

CA 02677068 2009-09-01
<SEQ ID NO. 937;RNA;Artificial Sequence> uuugacugcugug
<SEQ ID NO. 938;RNA;Artificial Sequence> ggagaugagagac
<SEQ ID NO. 939;RNA;Artificial Sequence> ucccacuugg
<SEQ ID NO. 940;RNA;Artificial Sequence> guucacggcc
<SEQ ID NO. 941;RNA;Artificial Sequence> accaucacacca
<SEQ ID NO. 942;RNA;Artificial Sequence> cugcggguuu
<SEQ ID NO. 943;RNA;Artificial Sequence> uccaguuug
<SEQ ID NO. 944;RNA;Artificial Sequence> uuaaggacuucu
<SEQ ID NO. 945;RNA;Artificial Sequence> agugggacagag
<SEQ ID NO. 946;RNA;Artificial Sequence> auuuguuauugug
<SEQ ID NO. 947;RNA;Artificial Sequence> ucaaaugcauuu
<SEQ ID NO. 948;RNA; Artificial Sequence> aggaaagcc
<SEQ ID NO. 949;RNA;Artificial Sequence> ggaaagcccu
<SEQ ID NO.950;RNA;Artificial Sequence> ccagcauggcc
<SEQ ID NO. 951;RNA;Artificial Sequence> uucucccuga
<SEQ ID NO. 952;RNA;Artificial Sequence> aagaagcccuu
<SEQ ID NO. 953;RNA;Artificial Sequence> gaagcccuuca
<SEQ ID NO. 954;RNA;Artificial Sequence> cccuucagcg
<SEQ ID NO. 955;RNA;Artificial Sequence> cuucagcggc
<SEQ ID NO.956;RNA;Artificial Sequence> cagcggccagu
<SEQ ID NO. 957;RNA;Artificial Sequence> gaaaagcuccg
<SEQ ID NO. 958;RNA;Artificial Sequence> aaagcuccgg
<SEQ ID NO. 959;RNA; Artificial Sequence> gucaacagucug
<SEQ ID NO. 960;RNA;Artificial Sequence> agaguucaaaag
<SEQ ID NO. 961;RNA;Artificial Sequence> gaguucaaaagc
<SEQ ID NO. 962;RNA;Artificial Sequence> ucaaaagcccu
<SEQ ID NO. 963;RNA;Artificial Sequence> caaaagcccuu
<SEQ ID NO. 964;RNA;Artificial Sequence> aaagcccuuca
<SEQ ID NO. 965;RNA;Artificial Sequence> aagcccuucag
<SEQ ID NO. 966;RNA;Artificial Sequence> ugaagccgcucg
<SEQ ID NO. 967;RNA;Artificial Sequence> acgccagucaa
<SEQ ID NO. 968;RNA;Artificial Sequence> ucuuggugcgug
<SEQ ID NO. 969;RNA;Artificial Sequence> uuggauucaucag
<SEQ ID NO. 970;RNA; Artificial Sequence> ggaauaccuaag
<SEQ ID NO. 971;RNA;Artificial Sequence> uuugaggcuca
<SEQ ID NO. 972;RNA;Artificial Sequence> cuacaauugg
<SEQ ID NO. 973;RNA;Artificial Sequence> aguuaggagec
<SEQ ID NO. 974;RNA;Artificial Sequence> gucaauauccac
<SEQ ID NO. 975;RNA;Artificial Sequence> uguucagucaca
<SEQ ID NO. 976;RNA;Artificial Sequence> cacacacauac
<SEQ ID NO. 977;RNA;Artificial Sequence> uccuuuugcuu
<SEQ ID NO. 978;RNA;Artificial Sequence> uuuaaaguaauuuuu
<SEQ ID NO. 979;RNA;Artificial Sequence> aacagucaaugg
<SEQ ID NO. 980;RNA;Artificial Sequence> cgacaaaccaau
<SEQ ID NO. 981;RNA;Artificial Sequence> cugcuaccacu
<SEQ ID NO. 982;RNA;Artificial Sequence> caagcggucuua
<SEQ ID NO. 983;RNA;Artificial Sequence> gucuuaccggcu
<SEQ ID NO. 984;RNA;Artificial Sequence> auggguuacc
<SEQ ID NO. 985;RNA;Artificial Sequence> uuaccugcga
<SEQ ID NO. 986;RNA;Artificial Sequence> aucuugcugag
<SEQ ID NO. 987;RNA;Artificial Sequence> gcauaaaacagu
<SEQ ID NO. 988;RNA;Artificial Sequence> uccuuuauccu
<SEQ ID NO. 989;RNA;Artificial Sequence> aacgcaaguug
<SEQ ID NO. 990;RNA;Artificial Sequence> aacugaaaccau
<SEQ ID NO. 991;RNA;Artificial Sequence> cuuuguuaaauau
<SEQ ID NO. 992;RNA;Artificial Sequence> uauauuaaaaguu
<SEQ ID NO. 993;RNA;Artificial Sequence> uuuugacuuaac
<SEQ ID NO. 994;RNA;Artificial Sequence> caaacucagcac
<SEQ ID NO. 995;RNA;Artificial Sequence> gcugaccuca
<SEQ ID NO. 996;RNA;Artificial Sequence> uuauucagaucgc
<SEQ ID NO. 997;RNA;Artificial Sequence> ggguucugggau
<SEQ ID NO. 998;RNA;Artificial Sequence> uauuggaaauuaug
<SEQ ID NO. 999;RNA;Artificial Sequence> uggaagcacuag
<SEQ ID NO. 1000;RNA;Artificial Sequence> uuuuuaugugga
<SEQ ID NO. 1001;RNA;Artificial Sequence> gaauugguaga
<SEQ ID NO. 1002;RNA;Artificial Sequence> uagacuuggaga
<SEQ ID NO. 1003;RNA;Artificial Sequence> uacaguauucca
<SEQ ID NO. I004;RNA;Artificial Sequence> cacugaugaauuaa
<SEQ ID NO. 1005;RNA;Artificial Sequence> cacaucaucac
<SEQ ID NO. 1006;RNA;Artificial Sequence> ucaccaaacaga
<SEQ ID NO. 1007;RNA;Artificial Sequence> gaacaugaugg
<SEQ ID NO. 1008;RNA;Artificial Sequence> auguagacugc
<SEQ ID NO. 1009;RNA;Artificial Sequence> gaucuauuuaug
741-3683

CA 02677068 2009-09-01
<SEQ ID NO. 1010;RNA;Artificial Sequence> cacuauuauca
<SEQ ID NO. 1011;RNA;Artificial Sequence> ucaguucugc
<SEQ ID NO. 1012;RNA;Artificial Sequence> gauuaaaccuac
<SEQ ID NO. 1013;RNA;Artificial Sequence> uaaaauccuucu
<SEQ ID NO. 1014;RNA;Artificial Sequence> augcuguagac
<SEQ ID NO. 1015;RNA;Artificial Sequence> ugauaggaauag
<SEQ ID NO. 1016;RNA;Artificial Sequence> auggcccuga
<SEQ ID NO. 1017;RNA;Artificial Sequence> uccucaagca
<SEQ ID NO. 1018;RNA;Artificial Sequence> uucagccca
<SEQ ID NO. 1019;RNA;Artificial Sequence> cugcugaacc
<SEQ ID NO. 1020;RNA;Artificial Sequence> aguucucuuca
<SEQ ID NO. 1021;RNA;Artificial Sequence> cagccuagag
<SEQ ID NO. 1022;RNA;Artificial Sequence> ucugugaagugu
<SEQ ID NO. 1023;RNA;Artificial Sequence> gagaaaauuucaa
<SEQ ID NO. 1024;RNA;Artificial Sequence> auccuccuga
<SEQ ID NO. 1025;RNA;Artificial Sequence> ugacaucauau
<SEQ ID NO. 1026;RNA;Artificial Sequence> aucuucaucaua
<SEQ ID NO. 1027;RNA;Artificial Sequence> acuagcuauuaa
<SEQ ID NO. 1028;RNA;Artificial Sequence> cucuacuaaaaau
<SEQ ID NO. 1029;RNA;Artificial Sequence> cuaucucgccu
<SEQ ID NO. 1030;RNA;Artificial Sequence> uucgguccaguu
<SEQ ID NO. 1031;RNA;Artificial Sequence> auguagccgc
<SEQ ID NO. 1032;RNA;Artificial Sequence> gaggagacuug
<SEQ ID NO. 1033;RNA;Artificial Sequence> aguagugagga
<SEQ ID NO. 1034;RNA;Artificial Sequence> agaugaguacaaa
<SEQ ID NO. 1035;RNA;Artificial Sequence> uuguuaaugggc
<SEQ ID NO. 1036;RNA;Artificial Sequence> uuuuaauuuauu
<SEQ ID NO. 1037;RNA;Artificial Sequence> auuuaaauaug
<SEQ ID NO. 1038;RNA;Artificial Sequence> auccuuuguuuc
<SEQ ID NO. 1039;RNA;Artificial Sequence> gucuaaguguuug
<SEQ ID NO. I040;RNA;Artificial Sequence> ccugugacaaa
<SEQ ID NO. 1041;RNA;Artificial Sequence> caggcugaauua
<SEQ ID NO. 1042;RNA;Artificial Sequence> ucauucuuacaau
<SEQ ID NO. 1043;RNA;Artificial Sequence> cauucuuacaauug
<SEQ ID NO. 1044;RNA;Artificial Sequence> agagaguguac
<SEQ ID NO. 1045;RNA;Artificial Sequence> gaacucagcag
<SEQ ID NO. 1046;RNA;Artificial Sequence> uuauuuucagua
<SEQ ID NO. 1047;RNA;Artificial Sequence> cuuaaauggaa
<SEQ ID NO. 1048;RNA;Artificial Sequence> gccuaaaauugu
<SEQ ID NO. 1049;RNA;Artificial Sequence> acuaacaucugg
<SEQ ID NO. 1050;RNA;Artificial Sequence> gacugugagcu
<SEQ ID NO. 1051;RNA;Artificial Sequence> gcuuuuuauuaau
<SEQ ID NO. 1052;RNA;Artificial Sequence> ucuucuuacauu
<SEQ ID NO. 1053;RNA;Artificial Sequence> auuuguaaaaaugu
<SEQ ID NO. 1054;RNA;Artificial Sequence> ucuuaauucauauu
<SEQ ID NO. 1055;RNA;Artificial Sequence> aacuaaucauga
<SEQ ID NO. 1056;RNA;Artificial Sequence> cugcucuuggg
<SEQ ID NO. 1057;RNA;Artificial Sequence> aguagcuuugag
<SEQ ID NO. 1058;RNA;Artificial Sequence> acguaauauuuca
<SEQ ID NO. 1059;RNA;Artificial Sequence> auucucuucacu
<SEQ ID NO. 1060;RNA;Artificial Sequence> uaaugcuaagaaa
<SEQ ID NO. 1061;RNA;Artificial Sequence> cugaaaaucaa
<SEQ ID NO. 1062;RNA;Artificial Sequence> auaugauuacuuu
<SEQ ID NO. 1063;RNA;Artificial Sequence> auuuuguucuaca
<SEQ ID NO. 1064;RNA;Artificial Sequence> ccgggacucuc
<SEQ ID NO. 1065;RNA;Artificial Sequence> cuuuaaaguaaag
<SEQ ID NO. 1066;RNA;Artificial Sequence> cuggaagccugg
<SEQ ID NO. 1067;RNA;Artificial Sequence> aaacaaaagagag
<SEQ ID NO. 1068;RNA;Artificial Sequence> ucaguuaugccg
<SEQ ID NO. 1069;RNA;Artificial Sequence> aaaagaagucca
<SEQ ID NO. 1070;RNA;Artificial Sequence> ggugagguua
<SEQ ID NO. 1071;RNA;Artificial Sequence> ggaagaggac
<SEQ ID NO. 1072;RNA;Artificial Sequence> agcaaguauugu
<SEQ ID NO. 1073;RNA;Artificial Sequence> uuguagcacuc
<SEQ ID NO. 1074;RNA;Artificial Sequence> caaaaccacaaau
<SEQ ID NO. 1075;RNA;Artificial Sequence> aagcccauaca
<SEQ ID NO. 1076;RNA;Artificial Sequence> gcccauacag
<SEQ ID NO. 1077;RNA;Artificial Sequence> agaaaccuucc
<SEQ ID NO. 1078;RNA;Artificial Sequence> uauaccuac
<SEQ ID NO. 1079;RNA;Artificial Sequence> ccaguuuucgga
<SEQ ID NO. 1080;RNA;Artificial Sequence> gaacaggg
<SEQ ID NO. 1081;RNA;Artificial Sequence> uaacuuuccagu
<SEQ ID NO. 1082;RNA;Artificial Sequence> aaguuugguuuug
741-3684

CA 02677068 2009-09-01
<SEQ ID NO. 1083;RNA;Artificial Sequence> uucccacugua
<SEQ ID NO. 1084;RNA;Artificial Sequence> gauaccauauga
<SEQ ID NO. 1085;RNA;Artificial Sequence> acaugggcug
<SEQ ID NO. 1086;RNA;Artificial Sequence> aacuuuuucaua
<SEQ ID NO. 1087;RNA;Artificial Sequence> augaggccgga
<SEQ ID NO. 1088;RNA;Artificial Sequence> cugcauuugu
<SEQ ID NO. 1089;RNA;Artificial Sequence> auguuuacuacc
<SEQ ID NO. 1090;RNA;Artificial Sequence> auuuuuugaugaaa
<SEQ ID NO. 1091;RNA;Artificial Sequence> agugugugaauuu
<SEQ ID NO. 1092;RNA;Artificial Sequence> agcaauguaugu
<SEQ ID NO. 1093;RNA;Artificial Sequence> aagcacauauaua
<SEQ ID NO. 1094;RNA;Artificial Sequence> uaauaguuucucc
<SEQ ID NO. 1095;RNA;Artificial Sequence> guuucuccaaau
<SEQ ID NO. 1096;RNA;Artificial Sequence> acuuccuagaaa
<SEQ ID NO. 1097;RNA;Artificial Sequence> acaccauauaug
<SEQ ID NO. 1098;RNA;Artificial Sequence> uauaugaauggag
<SEQ ID NO. 1099;RNA;Artificial Sequence> cauuuacaggga
<SEQ ID NO. I 100;RNA;Artificial Sequence> auuuacagggac
<SEQ ID NO. 1101;RNA;Artificial Sequence> gggaccuga
<SEQ ID NO. 1102;RNA;Artificial Sequence> guuugacugcauc
<SEQ ID NO. 1103;RNA;Artificial Sequence> uugacugcaucg
<SEQ ID NO. 1104;RNA;Artificial Sequence> aguucacaggg
<SEQ ID NO. 1105;RNA;Artificial Sequence> gcaccucugucc
<SEQ ID NO. 1106;RNA;Artificial Sequence> guuugucuuuuuaa
<SEQ ID NO. 1107;RNA;Artificial Sequence> uugucuuuuuaag
<SEQ ID NO. 1108;RNA;Artificial Sequence> cuaaagguuguc
<SEQ ID NO. 1109;RNA;Artificial Sequence> agguugucgac
<SEQ ID NO. 1110;RNA;Artificial Sequence> ccuggcaauugu
<SEQ ID NO. 1111;RNA;Artificial Sequence> guggugcgagg
<SEQ ID NO. 11 12;RNA;Artificial Sequence> gagacaugaaau
<SEQ ID NO. 11 13;RNA;Artificial Sequence> uauauuucucca
<SEQ ID NO. 11 14;RNA;Artificial Sequence> augaaggcu
<SEQ ID NO. 11 15;RNA;Artificial Sequence> cuggaguggu
<SEQ ID NO. 11 16;RNA;Artificial Sequence> ggaagagagg
<SEQ ID NO. 11 17;RNA;Artificial Sequence> uugcaucgggc
<SEQ ID NO. 11 18;RNA;Artificial Sequence> uauccuacugug
<SEQ ID NO. 11 19;RNA;Artificial Sequence> ccuacuguguaa
<SEQ ID NO. 1120;RNA;Artificial Sequence> cuuguagugua
<SEQ ID NO. 1121;RNA;Artificial Sequence> cuuuguugauug
<SEQ ID NO. 1122;RNA;Artificial Sequence> uuguugauugaaa
<SEQ ID NO. 1123;RNA;Artificial Sequence> ucuuuuucuuccau
<SEQ ID NO. 1124;RNA;Artificial Sequence> aucuuccuucua
<SEQ ID NO. 1125;RNA;Artificial Sequence> ugaaugcuucau
<SEQ ID NO. 1126;RNA;Artificial Sequence> gaaugcuucaug
<SEQ ID NO. 1127;RNA;Artificial Sequence> auucuacuuuga
<SEQ ID NO. 1128;RNA;Artificial Sequence> gcaacuacagac
<SEQ ID NO. 1129;RNA;Artificial Sequence> accaaggucaac
<SEQ ID NO. 1130;RNA;Artificial Sequence> gacuaucucgac
<SEQ ID NO. 1131;RNA;Artificial Sequence> accuucccaaac
<SEQ ID NO. 1132;RNA;Artificial Sequence> caagcuuagaacu
<SEQ ID NO. 1133;RNA;Artificial Sequence> gcuuagaacuuuaa
<SEQ ID NO. 1134;RNA;Artificial Sequence> aacuuuaagcaac
<SEQ ID NO. 1135;RNA;Artificial Sequence> agaccaccac
<SEQ ID NO. 1136;RNA;Artificial Sequence> cgagaaauaaagu
<SEQ ID NO. 1137;RNA;Artificial Sequence> gagaaauaaaguu
<SEQ ID NO. 1138;RNA;Artificial Sequence> ggaaaugaucc
<SEQ ID NO. 1139;RNA;Artificial Sequence> aagaaaugaaac
<SEQ ID NO. 1140;RNA;Artificial Sequence> uuuccauccucc
<SEQ ID NO. 1141;RNA;Artificial Sequence> cugaaaaucuuuga
<SEQ ID NO. 1142;RNA;Artificial Sequence> gccguucagg
<SEQ ID NO. 1143;RNA;Artificial Sequence> aggguccagaag
<SEQ ID NO. 1144;RNA;Artificial Sequence> caagacugcuug
<SEQ ID NO. 1145;RNA;Artificial Sequence> ccaugucuuugg
<SEQ ID NO. 1146;RNA;Artificial Sequence> ccugaaacac
<SEQ ID NO. 1147;RNA;Artificial Sequence> cucuguaccuc
<SEQ ID NO. 1148;RNA;Artificial Sequence> gcaagacaaga
<SEQ ID NO. 1149;RNA;Artificial Sequence> caagacaagaaa
<SEQ ID NO. 1150;RNA;Artificial Sequence> guacaagaucc
<SEQ ID NO. 1151;RNA;Artificial Sequence> guacuugcaga
<SEQ ID NO. 1152;RNA;Artificial Sequence> gaucgauacaga
<SEQ ID NO. 1153;RNA;Artificial Sequence> auaaaaauaaau
<SEQ ID NO. 1154;RNA;Artificial Sequence> aaaaauaaauau
<SEQ ID NO. 1155;RNA;Artificial Sequence> uugacugcugug
741-3685

CA 02677068 2009-09-01
<SEQ ID NO. 1156;RNA;Artificial Sequence> gagaugagagac
<SEQ ID NO. 1157;RNA;Artificial Sequence> cccacuugg
<SEQ ID NO. 1158;RNA;Homo sapiens>
AGAUGCAGGGGCGCAAACGCCAAAGGAGACCAGGCUGUAGGAAGAGAAGGGCAGAGCGCCGGACAGCUCG
GCCCGCUCCCCGUCCUUUGGGGCCGCGGCUGGGGAACUACAAGGCCCAGCAGGCAGCUGCAGGGGGCGGAGGCGGAG
GAGGGACCAGCGCGGGUGGGAGUGAGAGAGCGAGCCCUCGCGCCCCGCCGGCGCAUAGCGCUCGGAGCGCUCUUGCG
GCCACAGGCGCGGCGUCCUCGGCGGCGGGCGGCAGCUAGCGGGAGCCGGGACGCCGGUGCAGCCGCAGCGCGCGGAG
GAACCCGGGUGUGCCGGGAGCUGGGCGGCCACGUCCGGACGGGACCGAGACCCCUCGUAGCGCAUUGCGGCGACCUC
GCCUUCCCCGGCCGCGAGCGCGCCGCUGCUUGAAAAGCCGCGGAACCCAAGGACUUUUCUCCGGUCCGAGCUCGGGG
CGCCCCGCAGGGCGCACGGUACCCGUGCUGCAGUCGGGCACGCCGCGGCGCCGGGGCCUCCGCAGGGCGAUGGAGCCC
GGUCUGCAAGGAAAGUGAGGCGCCGCCGCUGCGUUCUGGAGGAGGGGGGCACAAGGUCUGGAGACCCCGGGUGGCGG
ACGGGAGCCCUCCCCCCGCCCCGCCUCCGGGGCACCAGCUCCGGCUCCAUUGUUCCCGCCCGGGCUGGAGGCGCCGAG
CACCGAGCGCCGCCGGGAGUCGAGCGCCGGCCGCGGAGCUCUUGCGACCCCGCCAGGACCCGAACAGAGCCCGGGGGC
GGCGGGCCGGAGCCGGGGACGCGGGCACACGCCCGCUCGCACAAGCCACGGCGGACUCUCCCGAGGCGGAACCUCCAC
GCCGAGCGAGGGUCAGUUUGAAAAGGAGGAUCGAGCUCACUGUGGAGUAUCCAUGGAGAUGUGGAGCCUUGUCACC
AACCUCUAACUGCAGAACUGGGAUGUGGAGCUGGAAGUGCCUCCUCUUCUGGGCUGUGCUGGUCACAGCCACACUCU
GCACCGCUAGGCCGUCCCCGACCUUGCCUGAACAAGCCCAGCCCUGGGGAGCCCCUGUGGAAGUGGAGUCCUUCCUG
GUCCACCCCGGUGACCUGCUGCAGCUUCGCUGUCGGCUGCGGGACGAUGUGCAGAGCAUCAACUGGCUGCGGGACGG
GGUGCAGCUGGCGGAAAGCAACCGCACCCGCAUCACAGGGGAGGAGGUGGAGGUGCAGGACUCCGUGCCCGCAGACU
CCGGCCUCUAUGCUUGCGUAACCAGCAGCCCCUCGGGCAGUGACACCACCUACUUCUCCGUCAAUGUUUCAGAUGCU
CUCCCCUCCUCGGAGGAUGAUGAUGAUGAUGAUGACUCCUCUUCAGAGGAGAAAGAAACAGAUAACACCAAACCAAA
CCCCGUAGCUCCAUAUUGGACAUCCCCAGAAAAGAUGGAAAAGAAAUUGCAUGCAGUGCCGGCUGCCAAGACAGUGA
AGUUCAAAUGCCCUUCCAGUGGGACCCCAAACCCCACACUGCGCUGGUUGAAAAAUGGCAAAGAAUUCAAACCUGAC
CACAGAAUUGGAGGCUACAAGGUCCGUUAUGCCACCUGGAGCAUCAUAAUGGACUCUGUGGUGCCCUCUGACAAGGG
CAACUACACCUGCAUUGUGGAGAAUGAGUACGGCAGCAUCAACCACACAUACCAGCUGGAUGUCGUGGAGCGGUCCC
CUCACCGGCCCAUCCUGCAAGCAGGGUUGCCCGCCAACAAAACAGUGGCCCUGGGUAGCAACGUGGAGUUCAUGUGU
AAGGUGUACAGUGACCCGCAGCCGCACAUCCAGUGGCUAAAGCACAUCGAGGUGAAUGGGAGCAAGAUUGGCCCAGA
CAACCUGCCUUAUGUCCAGAUCUUGAAGACUGCUGGAGUUAAUACCACCGACAAAGAGAUGGAGGUGCUUCACUUAA
GAAAUGUCUCCUUUGAGGACGCAGGGGAGUAUACGUGCUUGGCGGGUAACUCUAUCGGACUCUCCCAUCACUCUGCA
UGGUUGACCGUUCUGGAAGCCCUGGAAGAGAGGCCGGCAGUGAUGACCUCGCCCCUGUACCUGGAGAUCAUCAUCUA
UUGCACAGGGGCCUUCCUCAUCUCCUGCAUGGUGGGGUCGGUCAUCGUCUACAAGAUGAAGAGUGGUACCAAGAAGA
GUGACUUCCACAGCCAGAUGGCUGUGCACAAGCUGGCCAAGAGCAUCCCUCUGCGCAGACAGGUAACAGUGUCUGCU
GACUCCAGUGCAUCCAUGAACUCUGGGGUUCUUCUGGUUCGGCCAUCACGGCUCUCCUCCAGUGGGACUCCCAUGCU
AGCAGGGGUCUCUGAGUAUGAGCUUCCCGAAGACCCUCGCUGGGAGCUGCCUCGGGACAGACUGGUCUUAGGCAAAC
CCCUGGGAGAGGGCUGCUUUGGGCAGGUGGUGUUGGCAGAGGCUAUCGGGCUGGACAAGGACAAACCCAACCGUGU
GACCAAAGUGGCUGUGAAGAUGUUGAAGUCGGACGCAACAGAGAAAGACUUGUCAGACCUGAUCUCAGAAAUGGAG
AUGAUGAAGAUGAUCGGGAAGCAUAAGAAUAUCAUCAACCUGCUGGGGGCCUGCACGCAGGAUGGUCCCUUGUAUG
UCAUCGUGGAGUAUGCCUCCAAGGGCAACCUGCGGGAGUACCUGCAGGCCCGGAGGCCCCCAGGGCUGGAAUACUGC
UACAACCCCAGCCACAACCCAGAGGAGCAGCUCUCCUCCAAGGACCUGGUGUCCUGCGCCUACCAGGUGGCCCGAGGC
AUGGAGUAUCUGGCCUCCAAGAAGUGCAUACACCGAGACCUGGCAGCCAGGAAUGUCCUGGUGACAGAGGACAAUGU
GAUGAAGAUAGCAGACUUUGGCCUCGCACGGGACAUUCACCACAUCGACUACUAUAAAAAGACAACCAACGGCCGAC
UGCCUGUGAAGUGGAUGGCACCCGAGGCAUUAUUUGACCGGAUCUACACCCACCAGAGUGAUGUGUGGUCUUUCGGG
GUGCUCCUGUGGGAGAUCUUCACUCUGGGCGGCUCCCCAUACCCCGGUGUGCCUGUGGAGGAACUUUUCAAGCUGCU
GAAGGAGGGUCACCGCAUGGACAAGCCCAGUAACUGCACCAACGAGCUGUACAUGAUGAUGCGGGACUGCUGGCAUG
CAGUGCCCUCACAGAGACCCACCUUCAAGCAGCUGGUGGAAGACCUGGACCGCAUCGUGGCCUUGACCUCCAACCAG
GAGUACCUGGACCUGUCCAUGCCCCUGGACCAGUACUCCCCCAGCUUUCCCGACACCCGGAGCUCUACGUGCUCCUCA
GGGGAGGAUUCCGUCUUCUCUCAUGAGCCGCUGCCCGAGGAGCCCUGCCUGCCCCGACACCCAGCCCAGCUUGCCAAU
GGCGGACUCAAACGCCGCUGACUGCCACCCACACGCCCUCCCCAGACUCCACCGUCAGCUGUAACCCUCACCCACAGC
CCCUGCUGGGCCCACCACCUGUCCGUCCCUGUCCCCUUUCCUGCUGGCAGGAGCCGGCUGCCUACCAGGGGCCUUCCU
GUGUGGCCUGCCUUCACCCCACUCAGCUCACCUCUCCCUCCACCUCCUCUCCACCUGCUGGUGAGAGGUGCAAAGAGG
CAGAUCUUUGCUGCCAGCCACUUCAUCCCCUCCCAGAUGUUGGACCAACACCCCUCCCUGCCACCAGGCACUGCCUGG
AGGGCAGGGAGUGGGAGCCAAUGAACAGGCAUGCAAGUGAGAGCUUCCUGAGCUUUCUCCUGUCGGUUUGGUCUGU
UUUGCCUUCACCCAUAAGCCCCUCGCACUCUGGUGGCAGGUGCCUUGUCCUCAGGGCUACAGCAGUAGGGAGGUCAG
UGCUUCGUGCCUCGAUUGAAGGUGACCUCUGCCCCAGAUAGGUGGUGCCAGUGGCUUAUUAAUUCCGAUACUAGUUU
GCUUUGCUGACCAAAUGCCUGGUACCAGAGGAUGGUGAGGCGAAGGCCAGGUUGGGGGCAGUGUUGUGGCCCUGGG
GCCCAGCCCCAAACUGGGGGCUCUGUAUAUAGCUAUGAAGAAAACACAAAGUGUAUAAAUCUGAGUAUAUAUUUAC
AUGUCUUUUUAAAAGGGUCGUUACCAGAGAUUUACCCAUCGGGUAAGAUGCUCCUGGUGGCUGGGAGGCAUCAGUU
GCUAUAUAUUAAAAACAAAAAAGAAAAAAAAGGAAAAUGUUUUUAAAAAGGUCAUAUAUUUUUUGCUACUUUUGCU
GUUUUAUUUUUUUAAAUUAUGUUCUAAACCUAUUUUCAGUUUAGGUCCCUCAAUAAAAAUUGCUGCUGCUUCAUUU
AUCUAUGGGCUGUAUGAAAAGGGUGGGAAUGUCCACUGGAAAGAAGGGACACCCACGGGCCCUGGGGCUAGGUCUG
UCCCGAGGGCACCGCAUGCUCCCGGCGCAGGUUCCUUGUAACCUCUUCUUCCUAGGUCCUGCACCCAGACCUCACGAC
GCACCUCCUGCCUCUCCGCUGCUUUUGGAAAGUCAGAAAAAGAAGAUGUCUGCUUCGAGGGCAGGAACCCCAUCCAU
GCAGUAGAGGCGCUGGGCAGAGAGUCAAGGCCCAGCAGCCAUCGACCAUGGAUGGUUUCCUCCAAGGAAACCGGUGG
GGUUGGGCUGGGGAGGGGGCACCUACCUAGGAAUAGCCACGGGGUAGAGCUACAGUGAUUAAGAGGAAAGCAAGGG
CGCGGUUGCUCACGCCUGUAAUCCCAGCACUUUGGGACACCGAGGUGGGCAGAUCACUUCAGGUCAGGAGUUUGAGA
CCAGCCUGGCCAACUUAGUGAAACCCCAUCUCUACUAAAAAUGCAAAAAUUAUCCAGGCAUGGUGGCACACGCCUGU
AAUCCCAGCUCCACAGGAGGCUGAGGCAGAAUCCCUUGAAGCUGGGAGGCGGAGGUUGCAGUGAGCCGAGAUUGCGC
CAUUGCACUCCAGCCUGGGCAACAGAGAAAACAAAAAGGAAAACAAAUGAUGAAGGUCUGCAGAAACUGAAACCCA
GACAUGUGUCUGCCCCCUCUAUGUGGGCAUGGUUUUGCCAGUGCUUCUAAGUGCAGGAGAACAUGUCACCUGAGGCU
AGUUUUGCAUUCAGGUCCCUGGCUUCGUUUCUUGUUGGUAUGCCUCCCCAGAUCGUCCUUCCUGUAUCCAUGUGACC
AGACUGUAUUUGUUGGGACUGUCGCAGAUCUUGGCUUCUUACAGUUCUUCCUGUCCAAACUCCAUCCUGUCCCUCAG
GAACGGGGGGAAAAUUCUCCGAAUGUUUUUGGUUUUUUGGCUGCUUGGAAUUUACUUCUGCCACCUGCUGGUCAUC
ACUGUCCUCACUAAGUGGAUUCUGGCUCCCCCGUACCUCAUGGCUCAAACUACCACUCCUCAGUCGCUAUAUUAAAG
741-3686

CA 02677068 2009-09-01
CUUAUAUUUUGCUGGAUUACUGCUAAAUACAAAAGAAAGUUCAAUAUGUUUUCAUUUCUGUAGGGAAAAUGGGAUU
GCUGCUUUAAAUUUCUGAGCUAGGGAUUUUUUGGCAGCUGCAGUGUUGGCGACUAUUGUAAAAUUCUCUUUGUUUC
UCUCUGUAAAUAGCACCUGCUAACAUUACAAUUUGUAUUUAUGUUUAAAGAAGGCAUCAUUUGGUGAACAGAACUA
GGAAAUGAAUUUUUAGCUCUUAAAAGCAUUUGCUUUGAGACCGCACAGGAGUGUCUUUCCUUGUAAAACAGUGAUG
AUAAUUUCUGCCUUGGCCCUACCUUGAAGCAAUGUUGUGUGAAGGGAUGAAGAAUCUAAAAGUCUUCAUAAGUCCU
UGGGAGAGGUGCUAGAAAAAUAUAAGGCACUAUCAUAAUUACAGUGAUGUCCUUGCUGUUACUACUCAAAUCACCC
ACAAAUUUCCCCAAAGACUGCGCUAGCUGUCAAAUAAAAGACAGUGAAAUUGACCUGAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1159;RNA;Homo sapiens>
AGAUGCAGGGGCGCAAACGCCAAAGGAGACCAGGCUGUAGGAAGAGAAGGGCAGAGCGCCGGACAGCUCG
GCCCGCUCCCCGUCCUUUGGGGCCGCGGCUGGGGAACUACAAGGCCCAGCAGGCAGCUGCAGGGGGCGGAGGCGGAG
GAGGGACCAGCGCGGGUGGGAGUGAGAGAGCGAGCCCUCGCGCCCCGCCGGCGCAUAGCGCUCGGAGCGCUCUUGCG
GCCACAGGCGCGGCGUCCUCGGCGGCGGGCGGCAGCUAGCGGGAGCCGGGACGCCGGUGCAGCCGCAGCGCGCGGAG
GAACCCGGGUGUGCCGGGAGCUGGGCGGCCACGUCCGGACGGGACCGAGACCCCUCGUAGCGCAUUGCGGCGACCUC
GCCUUCCCCGGCCGCGAGCGCGCCGCUGCUUGAAAAGCCGCGGAACCCAAGGACUUUUCUCCGGUCCGAGCUCGGGG
CGCCCCGCAGGGCGCACGGUACCCGUGCUGCAGUCGGGCACGCCGCGGCGCCGGGGCCUCCGCAGGGCGAUGGAGCCC
GGUCUGCAAGGAAAGUGAGGCGCCGCCGCUGCGUUCUGGAGGAGGGGGGCACAAGGUCUGGAGACCCCGGGUGGCGG
ACGGGAGCCCUCCCCCCGCCCCGCCUCCGGGGCACCAGCUCCGGCUCCAUUGUUCCCGCCCGGGCUGGAGGCGCCGAG
CACCGAGCGCCGCCGGGAGUCGAGCGCCGGCCGCGGAGCUCUUGCGACCCCGCCAGGACCCGAACAGAGCCCGGGGGC
GGCGGGCCGGAGCCGGGGACGCGGGCACACGCCCGCUCGCACAAGCCACGGCGGACUCUCCCGAGGCGGAACCUCCAC
GCCGAGCGAGGGUCAGUUUGAAAAGGAGGAUCGAGCUCACUGUGGAGUAUCCAUGGAGAUGUGGAGCCUUGUCACC
AACCUCUAACUGCAGAACUGGGAUGUGGAGCUGGAAGUGCCUCCUCUUCUGGGCUGUGCUGGUCACAGCCACACUCU
GCACCGCUAGGCCGUCCCCGACCUUGCCUGAACAAGAUGCUCUCCCCUCCUCGGAGGAUGAUGAUGAUGAUGAUGAC
UCCUCUUCAGAGGAGAAAGAAACAGAUAACACCAAACCAAACCCCGUAGCUCCAUAUUGGACAUCCCCAGAAAAGAU
GGAAAAGAAAUUGCAUGCAGUGCCGGCUGCCAAGACAGUGAAGUUCAAAUGCCCUUCCAGUGGGACCCCAAACCCCA
CACUGCGCUGGUUGAAAAAUGGCAAAGAAUUCAAACCUGACCACAGAAUUGGAGGCUACAAGGUCCGUUAUGCCACC
UGGAGCAUCAUAAUGGACUCUGUGGUGCCCUCUGACAAGGGCAACUACACCUGCAUUGUGGAGAAUGAGUACGGCA
GCAUCAACCACACAUACCAGCUGGAUGUCGUGGAGCGGUCCCCUCACCGGCCCAUCCUGCAAGCAGGGUUGCCCGCC
AACAAAACAGUGGCCCUGGGUAGCAACGUGGAGUUCAUGUGUAAGGUGUACAGUGACCCGCAGCCGCACAUCCAGUG
GCUAAAGCACAUCGAGGUGAAUGGGAGCAAGAUUGGCCCAGACAACCUGCCUUAUGUCCAGAUCUUGAAGACUGCUG
GAGUUAAUACCACCGACAAAGAGAUGGAGGUGCUUCACUUAAGAAAUGUCUCCUUUGAGGACGCAGGGGAGUAUAC
GUGCUUGGCGGGUAACUCUAUCGGACUCUCCCAUCACUCUGCAUGGUUGACCGUUCUGGAAGCCCUGGAAGAGAGGC
CGGCAGUGAUGACCUCGCCCCUGUACCUGGAGAUCAUCAUCUAUUGCACAGGGGCCUUCCUCAUCUCCUGCAUGGUG
GGGUCGGUCAUCGUCUACAAGAUGAAGAGUGGUACCAAGAAGAGUGACUUCCACAGCCAGAUGGCUGUGCACAAGC
UGGCCAAGAGCAUCCCUCUGCGCAGACAGGUAACAGUGUCUGCUGACUCCAGUGCAUCCAUGAACUCUGGGGUUCUU
CUGGUUCGGCCAUCACGGCUCUCCUCCAGUGGGACUCCCAUGCUAGCAGGGGUCUCUGAGUAUGAGCUUCCCGAAGA
CCCUCGCUGGGAGCUGCCUCGGGACAGACUGGUCUUAGGCAAACCCCUGGGAGAGGGCUGCUUUGGGCAGGUGGUGU
UGGCAGAGGCUAUCGGGCUGGACAAGGACAAACCCAACCGUGUGACCAAAGUGGCUGUGAAGAUGUUGAAGUCGGA
CGCAACAGAGAAAGACUUGUCAGACCUGAUCUCAGAAAUGGAGAUGAUGAAGAUGAUCGGGAAGCAUAAGAAUAUC
AUCAACCUGCUGGGGGCCUGCACGCAGGAUGGUCCCUUGUAUGUCAUCGUGGAGUAUGCCUCCAAGGGCAACCUGCG
GGAGUACCUGCAGGCCCGGAGGCCCCCAGGGCUGGAAUACUGCUACAACCCCAGCCACAACCCAGAGGAGCAGCUCU
CCUCCAAGGACCUGGUGUCCUGCGCCUACCAGGUGGCCCGAGGCAUGGAGUAUCUGGCCUCCAAGAAGUGCAUACAC
CGAGACCUGGCAGCCAGGAAUGUCCUGGUGACAGAGGACAAUGUGAUGAAGAUAGCAGACUUUGGCCUCGCACGGG
ACAUUCACCACAUCGACUACUAUAAAAAGACAACCAACGGCCGACUGCCUGUGAAGUGGAUGGCACCCGAGGCAUUA
UUUGACCGGAUCUACACCCACCAGAGUGAUGUGUGGUCUUUCGGGGUGCUCCUGUGGGAGAUCUUCACUCUGGGCGG
CUCCCCAUACCCCGGUGUGCCUGUGGAGGAACUUUUCAAGCUGCUGAAGGAGGGUCACCGCAUGGACAAGCCCAGUA
ACUGCACCAACGAGCUGUACAUGAUGAUGCGGGACUGCUGGCAUGCAGUGCCCUCACAGAGACCCACCUUCAAGCAG
CUGGUGGAAGACCUGGACCGCAUCGUGGCCUUGACCUCCAACCAGGAGUACCUGGACCUGUCCAUGCCCCUGGACCA
GUACUCCCCCAGCUUUCCCGACACCCGGAGCUCUACGUGCUCCUCAGGGGAGGAUUCCGUCUUCUCUCAUGAGCCGC
UGCCCGAGGAGCCCUGCCUGCCCCGACACCCAGCCCAGCUUGCCAAUGGCGGACUCAAACGCCGCUGACUGCCACCCA
CACGCCCUCCCCAGACUCCACCGUCAGCUGUAACCCUCACCCACAGCCCCUGCUGGGCCCACCACCUGUCCGUCCCUG
UCCCCUUUCCUGCUGGCAGGAGCCGGCUGCCUACCAGGGGCCUUCCUGUGUGGCCUGCCUUCACCCCACUCAGCUCAC
CUCUCCCUCCACCUCCUCUCCACCUGCUGGUGAGAGGUGCAAAGAGGCAGAUCUUUGCUGCCAGCCACUUCAUCCCCU
CCCAGAUGUUGGACCAACACCCCUCCCUGCCACCAGGCACUGCCUGGAGGGCAGGGAGUGGGAGCCAAUGAACAGGC
AUGCAAGUGAGAGCUUCCUGAGCUUUCUCCUGUCGGUUUGGUCUGUUUUGCCUUCACCCAUAAGCCCCUCGCACUCU
GGUGGCAGGUGCCUUGUCCUCAGGGCUACAGCAGUAGGGAGGUCAGUGCUUCGUGCCUCGAUUGAAGGUGACCUCUG
CCCCAGAUAGGUGGUGCCAGUGGCUUAUUAAUUCCGAUACUAGUUUGCUUUGCUGACCAAAUGCCUGGUACCAGAGG
AUGGUGAGGCGAAGGCCAGGUUGGGGGCAGUGUUGUGGCCCUGGGGCCCAGCCCCAAACUGGGGGCUCUGUAUAUA
GCUAUGAAGAAAACACAAAGUGUAUAAAUCUGAGUAUAUAUUUACAUGUCUUUUUAAAAGGGUCGUUACCAGAGAU
UUACCCAUCGGGUAAGAUGCUCCUGGUGGCUGGGAGGCAUCAGUUGCUAUAUAUUAAAAACAAAAAAGAAAAAAAA
GGAAAAUGUUUUUAAAAAGGUCAUAUAUUUUUUGCUACUUUUGCUGUUUUAUUUUUUUAAAUUAUGUUCUAAACCU
AUUUUCAGUUUAGGUCCCUCAAUAAAAAUUGCUGCUGCUUCAUUUAUCUAUGGGCUGUAUGAAAAGGGUGGGAAUG
UCCACUGGAAAGAAGGGACACCCACGGGCCCUGGGGCUAGGUCUGUCCCGAGGGCACCGCAUGCUCCCGGCGCAGGU
UCCUUGUAACCUCUUCUUCCUAGGUCCUGCACCCAGACCUCACGACGCACCUCCUGCCUCUCCGCUGCUUUUGGAAAG
UCAGAAAAAGAAGAUGUCUGCUUCGAGGGCAGGAACCCCAUCCAUGCAGUAGAGGCGCUGGGCAGAGAGUCAAGGCC
CAGCAGCCAUCGACCAUGGAUGGUUUCCUCCAAGGAAACCGGUGGGGUUGGGCUGGGGAGGGGGCACCUACCUAGGA
AUAGCCACGGGGUAGAGCUACAGUGAUUAAGAGGAAAGCAAGGGCGCGGUUGCUCACGCCUGUAAUCCCAGCACUUU
GGGACACCGAGGUGGGCAGAUCACUUCAGGUCAGGAGUUUGAGACCAGCCUGGCCAACUUAGUGAAACCCCAUCUCU
ACUAAAAAUGCAAAAAUUAUCCAGGCAUGGUGGCACACGCCUGUAAUCCCAGCUCCACAGGAGGCUGAGGCAGAAUC
CCUUGAAGCUGGGAGGCGGAGGUUGCAGUGAGCCGAGAUUGCGCCAUUGCACUCCAGCCUGGGCAACAGAGAAAACA
AAAAGGAAAACAAAUGAUGAAGGUCUGCAGAAACUGAAACCCAGACAUGUGUCUGCCCCCUCUAUGUGGGCAUGGU
UUUGCCAGUGCUUCUAAGUGCAGGAGAACAUGUCACCUGAGGCUAGUUUUGCAUUCAGGUCCCUGGCUUCGUUUCUU
GUUGGUAUGCCUCCCCAGAUCGUCCUUCCUGUAUCCAUGUGACCAGACUGUAUUUGUUGGGACUGUCGCAGAUCUUG
GCUUCUUACAGUUCUUCCUGUCCAAACUCCAUCCUGUCCCUCAGGAACGGGGGGAAAAUUCUCCGAAUGUUUUUGGU
741-3687

CA 02677068 2009-09-01
UUUUUGGCUGCUUGGAAUUUACUUCUGCCACCUGCUGGUCAUCACUGUCCUCACUAAGUGGAUUCUGGCUCCCCCGU
ACCUCAUGGCUCAAACUACCACUCCUCAGUCGCUAUAUUAAAGCUUAUAUUUUGCUGGAUUACUGCUAAAUACAAAA
GAAAGUUCAAUAUGUUUUCAUUUCUGUAGGGAAAAUGGGAUUGCUGCUUUAAAUUUCUGAGCUAGGGAUUUUUUGG
CAGCUGCAGUGUUGGCGACUAUUGUAAAAUUCUCUUUGUUUCUCUCUGUAAAUAGCACCUGCUAACAUUACAAUUU
GUAUUUAUGUUUAAAGAAGGCAUCAUUUGGUGAACAGAACUAGGAAAUGAAUUUUUAGCUCUUAAAAGCAUUUGCU
UUGAGACCGCACAGGAGUGUCUUUCCUUGUAAAACAGUGAUGAUAAUUUCUGCCUUGGCCCUACCUUGAAGCAAUG
UUGUGUGAAGGGAUGAAGAAUCUAAAAGUCUUCAUAAGUCCUUGGGAGAGGUGCUAGAAAAAUAUAAGGCACUAUC
AUAAUUACAGUGAUGUCCUUGCUGUUACUACUCAAAUCACCCACAAAUUUCCCCAAAGACUGCGCUAGCUGUCAAAU
AAAAGACAGUGAAAUUGACCUGAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1160;RNA;Homo sapiens>
AGAUGCAGGGGCGCAAACGCCAAAGGAGACCAGGCUGUAGGAAGAGAAGGGCAGAGCGCCGGACAGCUCG
GCCCGCUCCCCGUCCUUUGGGGCCGCGGCUGGGGAACUACAAGGCCCAGCAGGCAGCUGCAGGGGGCGGAGGCGGAG
GAGGGACCAGCGCGGGUGGGAGUGAGAGAGCGAGCCCUCGCGCCCCGCCGGCGCAUAGCGCUCGGAGCGCUCUUGCG
GCCACAGGCGCGGCGUCCUCGGCGGCGGGCGGCAGCUAGCGGGAGCCGGGACGCCGGUGCAGCCGCAGCGCGCGGAG
GAACCCGGGUGUGCCGGGAGCUGGGCGGCCACGUCCGGACGGGACCGAGACCCCUCGUAGCGCAUUGCGGCGACCUC
GCCUUCCCCGGCCGCGAGCGCGCCGCUGCUUGAAAAGCCGCGGAACCCAAGGACUUUUCUCCGGUCCGAGCUCGGGG
CGCCCCGCAGGGCGCACGGUACCCGUGCUGCAGUCGGGCACGCCGCGGCGCCGGGGCCUCCGCAGGGCGAUGGAGCCC
GGUCUGCAAGGAAAGUGAGGCGCCGCCGCUGCGUUCUGGAGGAGGGGGGCACAAGGUCUGGAGACCCCGGGUGGCGG
ACGGGAGCCCUCCCCCCGCCCCGCCUCCGGGGCACCAGCUCCGGCUCCAUUGUUCCCGCCCGGGCUGGAGGCGCCGAG
CACCGAGCGCCGCCGGGAGUCGAGCGCCGGCCGCGGAGCUCUUGCGACCCCGCCAGGACCCGAACAGAGCCCGGGGGC
GGCGGGCCGGAGCCGGGGACGCGGGCACACGCCCGCUCGCACAAGCCACGGCGGACUCUCCCGAGGCGGAACCUCCAC
GCCGAGCGAGGGUCAGUUUGAAAAGGAGGAUCGAGCUCACUGUGGAGUAUCCAUGGAGAUGUGGAGCCUUGUCACC
AACCUCUAACUGCAGAACUGGGAUGUGGAGCUGGAAGUGCCUCCUCUUCUGGGCUGUGCUGGUCACAGCCACACUCU
GCACCGCUAGGCCGUCCCCGACCUUGCCUGAACAAGAUGCUCUCCCCUCCUCGGAGGAUGAUGAUGAUGAUGAUGAC
UCCUCUUCAGAGGAGAAAGAAACAGAUAACACCAAACCAAACCGUAUGCCCGUAGCUCCAUAUUGGACAUCCCCAGA
AAAGAUGGAAAAGAAAUUGCAUGCAGUGCCGGCUGCCAAGACAGUGAAGUUCAAAUGCCCUUCCAGUGGGACCCCAA
ACCCCACACUGCGCUGGUUGAAAAAUGGCAAAGAAUUCAAACCUGACCACAGAAUUGGAGGCUACAAGGUCCGUUAU
GCCACCUGGAGCAUCAUAAUGGACUCUGUGGUGCCCUCUGACAAGGGCAACUACACCUGCAUUGUGGAGAAUGAGUA
CGGCAGCAUCAACCACACAUACCAGCUGGAUGUCGUGGAGCGGUCCCCUCACCGGCCCAUCCUGCAAGCAGGGUUGC
CCGCCAACAAAACAGUGGCCCUGGGUAGCAACGUGGAGUUCAUGUGUAAGGUGUACAGUGACCCGCAGCCGCACAUC
CAGUGGCUAAAGCACAUCGAGGUGAAUGGGAGCAAGAUUGGCCCAGACAACCUGCCUUAUGUCCAGAUCUUGAAGAC
UGCUGGAGUUAAUACCACCGACAAAGAGAUGGAGGUGCUUCACUUAAGAAAUGUCUCCUUUGAGGACGCAGGGGAG
UAUACGUGCUUGGCGGGUAACUCUAUCGGACUCUCCCAUCACUCUGCAUGGUUGACCGUUCUGGAAGCCCUGGAAGA
GAGGCCGGCAGUGAUGACCUCGCCCCUGUACCUGGAGAUCAUCAUCUAUUGCACAGGGGCCUUCCUCAUCUCCUGCA
UGGUGGGGUCGGUCAUCGUCUACAAGAUGAAGAGUGGUACCAAGAAGAGUGACUUCCACAGCCAGAUGGCUGUGCA
CAAGCUGGCCAAGAGCAUCCCUCUGCGCAGACAGGUAACAGUGUCUGCUGACUCCAGUGCAUCCAUGAACUCUGGGG
UUCUUCUGGUUCGGCCAUCACGGCUCUCCUCCAGUGGGACUCCCAUGCUAGCAGGGGUCUCUGAGUAUGAGCUUCCC
GAAGACCCUCGCUGGGAGCUGCCUCGGGACAGACUGGUCUUAGGCAAACCCCUGGGAGAGGGCUGCUUUGGGCAGGU
GGUGUUGGCAGAGGCUAUCGGGCUGGACAAGGACAAACCCAACCGUGUGACCAAAGUGGCUGUGAAGAUGUUGAAG
UCGGACGCAACAGAGAAAGACUUGUCAGACCUGAUCUCAGAAAUGGAGAUGAUGAAGAUGAUCGGGAAGCAUAAGA
AUAUCAUCAACCUGCUGGGGGCCUGCACGCAGGAUGGUCCCUUGUAUGUCAUCGUGGAGUAUGCCUCCAAGGGCAAC
CUGCGGGAGUACCUGCAGGCCCGGAGGCCCCCAGGGCUGGAAUACUGCUACAACCCCAGCCACAACCCAGAGGAGCA
GCUCUCCUCCAAGGACCUGGUGUCCUGCGCCUACCAGGUGGCCCGAGGCAUGGAGUAUCUGGCCUCCAAGAAGUGCA
UACACCGAGACCUGGCAGCCAGGAAUGUCCUGGUGACAGAGGACAAUGUGAUGAAGAUAGCAGACUUUGGCCUCGCA
CGGGACAUUCACCACAUCGACUACUAUAAAAAGACAACCAACGGCCGACUGCCUGUGAAGUGGAUGGCACCCGAGGC
AUUAUUUGACCGGAUCUACACCCACCAGAGUGAUGUGUGGUCUUUCGGGGUGCUCCUGUGGGAGAUCUUCACUCUGG
GCGGCUCCCCAUACCCCGGUGUGCCUGUGGAGGAACUUUUCAAGCUGCUGAAGGAGGGUCACCGCAUGGACAAGCCC
AGUAACUGCACCAACGAGCUGUACAUGAUGAUGCGGGACUGCUGGCAUGCAGUGCCCUCACAGAGACCCACCUUCAA
GCAGCUGGUGGAAGACCUGGACCGCAUCGUGGCCUUGACCUCCAACCAGGAGUACCUGGACCUGUCCAUGCCCCUGG
ACCAGUACUCCCCCAGCUUUCCCGACACCCGGAGCUCUACGUGCUCCUCAGGGGAGGAUUCCGUCUUCUCUCAUGAG
CCGCUGCCCGAGGAGCCCUGCCUGCCCCGACACCCAGCCCAGCUUGCCAAUGGCGGACUCAAACGCCGCUGACUGCCA
CCCACACGCCCUCCCCAGACUCCACCGUCAGCUGUAACCCUCACCCACAGCCCCUGCUGGGCCCACCACCUGUCCGUC
CCUGUCCCCUUUCCUGCUGGCAGGAGCCGGCUGCCUACCAGGGGCCUUCCUGUGUGGCCUGCCUUCACCCCACUCAGC
UCACCUCUCCCUCCACCUCCUCUCCACCUGCUGGUGAGAGGUGCAAAGAGGCAGAUCUUUGCUGCCAGCCACUUCAU
CCCCUCCCAGAUGUUGGACCAACACCCCUCCCUGCCACCAGGCACUGCCUGGAGGGCAGGGAGUGGGAGCCAAUGAA
CAGGCAUGCAAGUGAGAGCUUCCUGAGCUUUCUCCUGUCGGUUUGGUCUGUUUUGCCUUCACCCAUAAGCCCCUCGC
ACUCUGGUGGCAGGUGCCUUGUCCUCAGGGCUACAGCAGUAGGGAGGUCAGUGCUUCGUGCCUCGAUUGAAGGUGAC
CUCUGCCCCAGAUAGGUGGUGCCAGUGGCUUAUUAAUUCCGAUACUAGUUUGCUUUGCUGACCAAAUGCCUGGUACC
AGAGGAUGGUGAGGCGAAGGCCAGGUUGGGGGCAGUGUUGUGGCCCUGGGGCCCAGCCCCAAACUGGGGGCUCUGU
AUAUAGCUAUGAAGAAAACACAAAGUGUAUAAAUCUGAGUAUAUAUUUACAUGUCUUUUUAAAAGGGUCGUUACCA
GAGAUUUACCCAUCGGGUAAGAUGCUCCUGGUGGCUGGGAGGCAUCAGUUGCUAUAUAUUAAAAACAAAAAAGAAA
AAAAAGGAAAAUGUUUUUAAAAAGGUCAUAUAUUUUUUGCUACUUUUGCUGUUUUAUUUUUUUAAAUUAUGUUCUA
AACCUAUUUUCAGUUUAGGUCCCUCAAUAAAAAUUGCUGCUGCUUCAUUUAUCUAUGGGCUGUAUGAAAAGGGUGG
GAAUGUCCACUGGAAAGAAGGGACACCCACGGGCCCUGGGGCUAGGUCUGUCCCGAGGGCACCGCAUGCUCCCGGCG
CAGGUUCCUUGUAACCUCUUCUUCCUAGGUCCUGCACCCAGACCUCACGACGCACCUCCUGCCUCUCCGCUGCUUUUG
GAAAGUCAGAAAAAGAAGAUGUCUGCUUCGAGGGCAGGAACCCCAUCCAUGCAGUAGAGGCGCUGGGCAGAGAGUC
AAGGCCCAGCAGCCAUCGACCAUGGAUGGUUUCCUCCAAGGAAACCGGUGGGGUUGGGCUGGGGAGGGGGCACCUAC
CUAGGAAUAGCCACGGGGUAGAGCUACAGUGAUUAAGAGGAAAGCAAGGGCGCGGUUGCUCACGCCUGUAAUCCCA
GCACUUUGGGACACCGAGGUGGGCAGAUCACUUCAGGUCAGGAGUUUGAGACCAGCCUGGCCAACUUAGUGAAACCC
CAUCUCUACUAAAAAUGCAAAAAUUAUCCAGGCAUGGUGGCACACGCCUGUAAUCCCAGCUCCACAGGAGGCUGAGG
CAGAAUCCCUUGAAGCUGGGAGGCGGAGGUUGCAGUGAGCCGAGAUUGCGCCAUUGCACUCCAGCCUGGGCAACAGA
GAAAACAAAAAGGAAAACAAAUGAUGAAGGUCUGCAGAAACUGAAACCCAGACAUGUGUCUGCCCCCUCUAUGUGG
GCAUGGUUUUGCCAGUGCUUCUAAGUGCAGGAGAACAUGUCACCUGAGGCUAGUUUUGCAUUCAGGUCCCUGGCUUC
741-3688

CA 02677068 2009-09-01
GUUUCUUGUUGGUAUGCCUCCCCAGAUCGUCCUUCCUGUAUCCAUGUGACCAGACUGUAUUUGUUGGGACUGUCGCA
GAUCUUGGCUUCUUACAGUUCUUCCUGUCCAAACUCCAUCCUGUCCCUCAGGAACGGGGGGAAAAUUCUCCGAAUGU
UUUUGGUUUUUUGGCUGCUUGGAAUUUACUUCUGCCACCUGCUGGUCAUCACUGUCCUCACUAAGUGGAUUCUGGCU
CCCCCGUACCUCAUGGCUCAAACUACCACUCCUCAGUCGCUAUAUUAAAGCUUAUAUUUUGCUGGAUUACUGCUAAA
UACAAAAGAAAGUUCAAUAUGUUUUCAUUUCUGUAGGGAAAAUGGGAUUGCUGCUUUAAAUUUCUGAGCUAGGGAU
UUUUUGGCAGCUGCAGUGUUGGCGACUAUUGUAAAAUUCUCUUUGUUUCUCUCUGUAAAUAGCACCUGCUAACAUU
ACAAUUUGUAUUUAUGUUUAAAGAAGGCAUCAUUUGGUGAACAGAACUAGGAAAUGAAUUUUUAGCUCUUAAAAGC
AUUUGCUUUGAGACCGCACAGGAGUGUCUUUCCUUGUAAAACAGUGAUGAUAAUUUCUGCCUUGGCCCUACCUUGA
AGCAAUGUUGUGUGAAGGGAUGAAGAAUCUAAAAGUCUUCAUAAGUCCUUGGGAGAGGUGCUAGAAAAAUAUAAGG
CACUAUCAUAAUUACAGUGAUGUCCUUGCUGUUACUACUCAAAUCACCCACAAAUUUCCCCAAAGACUGCGCUAGCU
GUCAAAUAAAAGACAGUGAAAUUGACCUGAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1161;RNA;Homo sapiens>
AGAUGCAGGGGCGCAAACGCCAAAGGAGACCAGGCUGUAGGAAGAGAAGGGCAGAGCGCCGGACAGCUCG
GCCCGCUCCCCGUCCUUUGGGGCCGCGGCUGGGGAACUACAAGGCCCAGCAGGCAGCUGCAGGGGGCGGAGGCGGAG
GAGGGACCAGCGCGGGUGGGAGUGAGAGAGCGAGCCCUCGCGCCCCGCCGGCGCAUAGCGCUCGGAGCGCUCUUGCG
GCCACAGGCGCGGCGUCCUCGGCGGCGGGCGGCAGCUAGCGGGAGCCGGGACGCCGGUGCAGCCGCAGCGCGCGGAG
GAACCCGGGUGUGCCGGGAGCUGGGCGGCCACGUCCGGACGGGACCGAGACCCCUCGUAGCGCAUUGCGGCGACCUC
GCCUUCCCCGGCCGCGAGCGCGCCGCUGCUUGAAAAGCCGCGGAACCCAAGGACUUUUCUCCGGUCCGAGCUCGGGG
CGCCCCGCAGGGCGCACGGUACCCGUGCUGCAGUCGGGCACGCCGCGGCGCCGGGGCCUCCGCAGGGCGAUGGAGCCC
GGUCUGCAAGGAAAGUGAGGCGCCGCCGCUGCGUUCUGGAGGAGGGGGGCACAAGGUCUGGAGACCCCGGGUGGCGG
ACGGGAGCCCUCCCCCCGCCCCGCCUCCGGGGCACCAGCUCCGGCUCCAUUGUUCCCGCCCGGGCUGGAGGCGCCGAG
CACCGAGCGCCGCCGGGAGUCGAGCGCCGGCCGCGGAGCUCUUGCGACCCCGCCAGGACCCGAACAGAGCCCGGGGGC
GGCGGGCCGGAGCCGGGGACGCGGGCACACGCCCGCUCGCACAAGCCACGGCGGACUCUCCCGAGGCGGAACCUCCAC
GCCGAGCGAGGGUCAGUUUGAAAAGGAGGAUCGAGCUCACUGUGGAGUAUCCAUGGAGAUGUGGAGCCUUGUCACC
AACCUCUAACUGCAGAACUGGGAUGUGGAGCUGGAAGUGCCUCCUCUUCUGGGCUGUGCUGGUCACAGCCACACUCU
GCACCGCUAGGCCGUCCCCGACCUUGCCUGAACAAGAUGCUCUCCCCUCCUCGGAGGAUGAUGAUGAUGAUGAUGAC
UCCUCUUCAGAGGAGAAAGAAACAGAUAACACCAAACCAAACCGUAUGCCCGUAGCUCCAUAUUGGACAUCCCCAGA
AAAGAUGGAAAAGAAAUUGCAUGCAGUGCCGGCUGCCAAGACAGUGAAGUUCAAAUGCCCUUCCAGUGGGACCCCAA
ACCCCACACUGCGCUGGUUGAAAAAUGGCAAAGAAUUCAAACCUGACCACAGAAUUGGAGGCUACAAGGUCCGUUAU
GCCACCUGGAGCAUCAUAAUGGACUCUGUGGUGCCCUCUGACAAGGGCAACUACACCUGCAUUGUGGAGAAUGAGUA
CGGCAGCAUCAACCACACAUACCAGCUGGAUGUCGUGGAGCGGUCCCCUCACCGGCCCAUCCUGCAAGCAGGGUUGC
CCGCCAACAAAACAGUGGCCCUGGGUAGCAACGUGGAGUUCAUGUGUAAGGUGUACAGUGACCCGCAGCCGCACAUC
CAGUGGCUAAAGCACAUCGAGGUGAAUGGGAGCAAGAUUGGCCCAGACAACCUGCCUUAUGUCCAGAUCUUGAAGG
UAAUCAUGGCACCAGUCUUCGUGGGCCAGUCUACUGGGAAGGAGACCACUGUCUCGGGGGCUCAAGUUCCUGUGGGC
AGGCUCAGUUGCCCCCGAAUGGGAUCAUUCCUCACGCUUCAGGCACACACACUCCAUCUCAGUAGGGAUCUAGCCAC
AUCCCCCAGGACUAGUAACAGAGGUCACAAAGUGGAGGUGAGCUGGGAACAGAGGGCUGCAGGGAUGGGUGGUGCU
GGUCUGUAAUAAGCUUUGAGAGCAACGUCACUGGGGCUUUGGGGUCAGCUACACAAGGAAGGCAUUUGGACCCCUG
CCUUUUCAUUGCCCGAAACCAGAGCCUUUCCACCAAGCGUUUCCCAGUCUUAGCCCUGUGUCCUGAGUUACGUACGA
UCUUUCUGGCAAAUGGGGUGCAUGAUAAGAGCAUCUCUUACGAAGAGUUGGAAAAACAAAUGCCAUAUAUAAAUUC
UAAGCCAUAUGAGGACGAGGAGUAAUGGCAUUUUCUUCCUUUUUCCUCUCACUCCCAGACAUUCAUUGUCCCUGAAU
GCUCCAUUAAUCCAGGGAAGGUAAUUGCCUAAAUCUCCAGUGGAUCUCGCAACAGGAAGGAACCAGAAGCUGGGAA
AGUUGUUUACCUCUUUGUCCCAGAGUUAGACCUCAUCCUCCCCUAGCUUAGCUGUCUCAGAGAUAUACUGGCCCUCC
CUUCUCUUCUCUUUGCUGCUGGUGCUAAAACUGCUCUGUAGGUCAUUGGCCACUGUCUCCACUCACAACCCCUGCUC
CAGUCCUGGAGGGAGUGGGUUAAACACAAAUAGAACAUUCCAUUUGAAGCAGUGAUUCUUUUUUUUUUUUUUUUUU
UUUAAUCAAAUGCUUUGGACUUUUGAAGUCCACUUGUUCUGUACUUGUAAAAGGGAAAGAAGGCCGGGCGCAGUGG
CUCACGCCUGUAAUCCCAGCACUUUAGAUCACUUGAGGUCAGGAGUUUGAGACCAGCCCGGCCAACAUGGUGAAACC
CCAUCUCUACUAAAAAUACAAAAAUUAGCUGUGCAUAGUGGUUGGCACCUGUAGUCCCAGCUACUCAGGAGGCUGAG
GCAAGCUAACUGCUUGAACCCAGAAGGCAGAGGUUGCAGUGAGCUGAGAUCACGCCACUGCACUCCAGCCUGGGUGA
CAGAGUGAGUGAGACUCUGCGUUAAAAAAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1162;RNA;Homo sapiens>
AGAUGCAGGGGCGCAAACGCCAAAGGAGACCAGGCUGUAGGAAGAGAAGGGCAGAGCGCCGGACAGCUCG
GCCCGCUCCCCGUCCUUUGGGGCCGCGGCUGGGGAACUACAAGGCCCAGCAGGCAGCUGCAGGGGGCGGAGGCGGAG
GAGGGACCAGCGCGGGUGGGAGUGAGAGAGCGAGCCCUCGCGCCCCGCCGGCGCAUAGCGCUCGGAGCGCUCUUGCG
GCCACAGGCGCGGCGUCCUCGGCGGCGGGCGGCAGCUAGCGGGAGCCGGGACGCCGGUGCAGCCGCAGCGCGCGGAG
GAACCCGGGUGUGCCGGGAGCUGGGCGGCCACGUCCGGACGGGACCGAGACCCCUCGUAGCGCAUUGCGGCGACCUC
GCCUUCCCCGGCCGCGAGCGCGCCGCUGCUUGAAAAGCCGCGGAACCCAAGGACUUUUCUCCGGUCCGAGCUCGGGG
CGCCCCGCAGGGCGCACGGUACCCGUGCUGCAGUCGGGCACGCCGCGGCGCCGGGGCCUCCGCAGGGCGAUGGAGCCC
GGUCUGCAAGGAAAGUGAGGCGCCGCCGCUGCGUUCUGGAGGAGGGGGGCACAAGGUCUGGAGACCCCGGGUGGCGG
ACGGGAGCCCUCCCCCCGCCCCGCCUCCGGGGCACCAGCUCCGGCUCCAUUGUUCCCGCCCGGGCUGGAGGCGCCGAG
CACCGAGCGCCGCCGGGAGUCGAGCGCCGGCCGCGGAGCUCUUGCGACCCCGCCAGGACCCGAACAGAGCCCGGGGGC
GGCGGGCCGGAGCCGGGGACGCGGGCACACGCCCGCUCGCACAAGCCACGGCGGACUCUCCCGAGGCGGAACCUCCAC
GCCGAGCGAGGGUCAGUUUGAAAAGGAGGAUCGAGCUCACUGUGGAGUAUCCAUGGAGAUGUGGAGCCUUGUCACC
AACCUCUAACUGCAGAACUGGGAUGUGGAGCUGGAAGUGCCUCCUCUUCUGGGCUGUGCUGGUCACAGCCACACUCU
GCACCGCUAGGCCGUCCCCGACCUUGCCUGAACAAGAUGCUCUCCCCUCCUCGGAGGAUGAUGAUGAUGAUGAUGAC
UCCUCUUCAGAGGAGAAAGAAACAGAUAACACCAAACCAAACCCCGUAGCUCCAUAUUGGACAUCCCCAGAAAAGAU
GGAAAAGAAAUUGCAUGCAGUGCCGGCUGCCAAGACAGUGAAGUUCAAAUGCCCUUCCAGUGGGACCCCAAACCCCA
CACUGCGCUGGUUGAAAAAUGGCAAAGAAUUCAAACCUGACCACAGAAUUGGAGGCUACAAGGUCCGUUAUGCCACC
UGGAGCAUCAUAAUGGACUCUGUGGUGCCCUCUGACAAGGGCAACUACACCUGCAUUGUGGAGAAUGAGUACGGCA
GCAUCAACCACACAUACCAGCUGGAUGUCGUGGAGCGGUCCCCUCACCGGCCCAUCCUGCAAGCAGGGUUGCCCGCC
AACAAAACAGUGGCCCUGGGUAGCAACGUGGAGUUCAUGUGUAAGGUGUACAGUGACCCGCAGCCGCACAUCCAGUG
GCUAAAGCACAUCGAGGUGAAUGGGAGCAAGAUUGGCCCAGACAACCUGCCUUAUGUCCAGAUCUUGAAGGUAAUC
AUGGCACCAGUCUUCGUGGGCCAGUCUACUGGGAAGGAGACCACUGUCUCGGGGGCUCAAGUUCCUGUGGGCAGGCU
CAGUUGCCCCCGAAUGGGAUCAUUCCUCACGCUUCAGGCACACACACUCCAUCUCAGUAGGGAUCUAGCCACAUCCC
741-3689

CA 02677068 2009-09-01
CCAGGACUAGUAACAGAGGUCACAAAGUGGAGGUGAGCUGGGAACAGAGGGCUGCAGGGAUGGGUGGUGCUGGUCU
GUAAUAAGCUUUGAGAGCAACGUCACUGGGGCUUUGGGGUCAGCUACACAAGGAAGGCAUUUGGACCCCUGCCUUU
UCAUUGCCCGAAACCAGAGCCUUUCCACCAAGCGUUUCCCAGUCUUAGCCCUGUGUCCUGAGUUACGUACGAUCUUU
CUGGCAAAUGGGGUGCAUGAUAAGAGCAUCUCUUACGAAGAGUUGGAAAAACAAAUGCCAUAUAUAAAUUCUAAGC
CAUAUGAGGACGAGGAGUAAUGGCAUUUUCUUCCUUUUUCCUCUCACUCCCAGACAUUCAUUGUCCCUGAAUGCUCC
AUUAAUCCAGGGAAGGUAAUUGCCUAAAUCUCCAGUGGAUCUCGCAACAGGAAGGAACCAGAAGCUGGGAAAGUUG
UUUACCUCUUUGUCCCAGAGUUAGACCUCAUCCUCCCCUAGCUUAGCUGUCUCAGAGAUAUACUGGCCCUCCCUUCU
CUUCUCUUUGCUGCUGGUGCUAAAACUGCUCUGUAGGUCAUUGGCCACUGUCUCCACUCACAACCCCUGCUCCAGUC
CUGGAGGGAGUGGGUUAAACACAAAUAGAACAUUCCAUUUGAAGCAGUGAUUCUUUUUUUUUUUUUUUUUUUUUAA
UCAAAUGCUUUGGACUUUUGAAGUCCACUUGUUCUGUACUUGUAAAAGGGAAAGAAGGCCGGGCGCAGUGGCUCAC
GCCUGUAAUCCCAGCACUUUAGAUCACUUGAGGUCAGGAGUUUGAGACCAGCCCGGCCAACAUGGUGAAACCCCAUC
UCUACUAAAAAUACAAAAAUUAGCUGUGCAUAGUGGUUGGCACCUGUAGUCCCAGCUACUCAGGAGGCUGAGGCAA
GCUAACUGCUUGAACCCAGAAGGCAGAGGUUGCAGUGAGCUGAGAUCACGCCACUGCACUCCAGCCUGGGUGACAGA
GUGAGUGAGACUCUGCGUUAAAAAAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1163;RNA;Homo sapiens>
AGAUGCAGGGGCGCAAACGCCAAAGGAGACCAGGCUGUAGGAAGAGAAGGGCAGAGCGCCGGACAGCUCG
GCCCGCUCCCCGUCCUUUGGGGCCGCGGCUGGGGAACUACAAGGCCCAGCAGGCAGCUGCAGGGGGCGGAGGCGGAG
GAGGGACCAGCGCGGGUGGGAGUGAGAGAGCGAGCCCUCGCGCCCCGCCGGCGCAUAGCGCUCGGAGCGCUCUUGCG
GCCACAGGCGCGGCGUCCUCGGCGGCGGGCGGCAGCUAGCGGGAGCCGGGACGCCGGUGCAGCCGCAGCGCGCGGAG
GAACCCGGGUGUGCCGGGAGCUGGGCGGCCACGUCCGGACGGGACCGAGACCCCUCGUAGCGCAUUGCGGCGACCUC
GCCUUCCCCGGCCGCGAGCGCGCCGCUGCUUGAAAAGCCGCGGAACCCAAGGACUUUUCUCCGGUCCGAGCUCGGGG
CGCCCCGCAGGGCGCACGGUACCCGUGCUGCAGUCGGGCACGCCGCGGCGCCGGGGCCUCCGCAGGGCGAUGGAGCCC
GGUCUGCAAGGAAAGUGAGGCGCCGCCGCUGCGUUCUGGAGGAGGGGGGCACAAGGUCUGGAGACCCCGGGUGGCGG
ACGGGAGCCCUCCCCCCGCCCCGCCUCCGGGGCACCAGCUCCGGCUCCAUUGUUCCCGCCCGGGCUGGAGGCGCCGAG
CACCGAGCGCCGCCGGGAGUCGAGCGCCGGCCGCGGAGCUCUUGCGACCCCGCCAGGACCCGAACAGAGCCCGGGGGC
GGCGGGCCGGAGCCGGGGACGCGGGCACACGCCCGCUCGCACAAGCCACGGCGGACUCUCCCGAGGCGGAACCUCCAC
GCCGAGCGAGGGUCAGUUUGAAAAGGAGGAUCGAGCUCACUGUGGAGUAUCCAUGGAGAUGUGGAGCCUUGUCACC
AACCUCUAACUGCAGAACUGGGAUGUGGAGCUGGAAGUGCCUCCUCUUCUGGGCUGUGCUGGUCACAGCCACACUCU
GCACCGCUAGGCCGUCCCCGACCUUGCCUGAACAAGCCCAGCCCUGGGGAGCCCCUGUGGAAGUGGAGUCCUUCCUG
GUCCACCCCGGUGACCUGCUGCAGCUUCGCUGUCGGCUGCGGGACGAUGUGCAGAGCAUCAACUGGCUGCGGGACGG
GGUGCAGCUGGCGGAAAGCAACCGCACCCGCAUCACAGGGGAGGAGGUGGAGGUGCAGGACUCCGUGCCCGCAGACU
CCGGCCUCUAUGCUUGCGUAACCAGCAGCCCCUCGGGCAGUGACACCACCUACUUCUCCGUCAAUGUUUCAGAUGCU
CUCCCCUCCUCGGAGGAUGAUGAUGAUGAUGAUGACUCCUCUUCAGAGGAGAAAGAAACAGAUAACACCAAACCAAA
CCGUAUGCCCGUAGCUCCAUAUUGGACAUCCCCAGAAAAGAUGGAAAAGAAAUUGCAUGCAGUGCCGGCUGCCAAGA
CAGUGAAGUUCAAAUGCCCUUCCAGUGGGACCCCAAACCCCACACUGCGCUGGUUGAAAAAUGGCAAAGAAUUCAAA
CCUGACCACAGAAUUGGAGGCUACAAGGUCCGUUAUGCCACCUGGAGCAUCAUAAUGGACUCUGUGGUGCCCUCUGA
CAAGGGCAACUACACCUGCAUUGUGGAGAAUGAGUACGGCAGCAUCAACCACACAUACCAGCUGGAUGUCGUGGAGC
GGUCCCCUCACCGGCCCAUCCUGCAAGCAGGGUUGCCCGCCAACAAAACAGUGGCCCUGGGUAGCAACGUGGAGUUC
AUGUGUAAGGUGUACAGUGACCCGCAGCCGCACAUCCAGUGGCUAAAGCACAUCGAGGUGAAUGGGAGCAAGAUUG
GCCCAGACAACCUGCCUUAUGUCCAGAUCUUGAAGACUGCUGGAGUUAAUACCACCGACAAAGAGAUGGAGGUGCUU
CACUUAAGAAAUGUCUCCUUUGAGGACGCAGGGGAGUAUACGUGCUUGGCGGGUAACUCUAUCGGACUCUCCCAUCA
CUCUGCAUGGUUGACCGUUCUGGAAGCCCUGGAAGAGAGGCCGGCAGUGAUGACCUCGCCCCUGUACCUGGAGAUCA
UCAUCUAUUGCACAGGGGCCUUCCUCAUCUCCUGCAUGGUGGGGUCGGUCAUCGUCUACAAGAUGAAGAGUGGUACC
AAGAAGAGUGACUUCCACAGCCAGAUGGCUGUGCACAAGCUGGCCAAGAGCAUCCCUCUGCGCAGACAGGUAACAGU
GUCUGCUGACUCCAGUGCAUCCAUGAACUCUGGGGUUCUUCUGGUUCGGCCAUCACGGCUCUCCUCCAGUGGGACUC
CCAUGCUAGCAGGGGUCUCUGAGUAUGAGCUUCCCGAAGACCCUCGCUGGGAGCUGCCUCGGGACAGACUGGUCUUA
GGCAAACCCCUGGGAGAGGGCUGCUUUGGGCAGGUGGUGUUGGCAGAGGCUAUCGGGCUGGACAAGGACAAACCCA
ACCGUGUGACCAAAGUGGCUGUGAAGAUGUUGAAGUCGGACGCAACAGAGAAAGACUUGUCAGACCUGAUCUCAGA
AAUGGAGAUGAUGAAGAUGAUCGGGAAGCAUAAGAAUAUCAUCAACCUGCUGGGGGCCUGCACGCAGGAUGGUCCC
UUGUAUGUCAUCGUGGAGUAUGCCUCCAAGGGCAACCUGCGGGAGUACCUGCAGGCCCGGAGGCCCCCAGGGCUGGA
AUACUGCUACAACCCCAGCCACAACCCAGAGGAGCAGCUCUCCUCCAAGGACCUGGUGUCCUGCGCCUACCAGGUGG
CCCGAGGCAUGGAGUAUCUGGCCUCCAAGAAGUGCAUACACCGAGACCUGGCAGCCAGGAAUGUCCUGGUGACAGAG
GACAAUGUGAUGAAGAUAGCAGACUUUGGCCUCGCACGGGACAUUCACCACAUCGACUACUAUAAAAAGACAACCAA
CGGCCGACUGCCUGUGAAGUGGAUGGCACCCGAGGCAUUAUUUGACCGGAUCUACACCCACCAGAGUGAUGUGUGGU
CUUUCGGGGUGCUCCUGUGGGAGAUCUUCACUCUGGGCGGCUCCCCAUACCCCGGUGUGCCUGUGGAGGAACUUUUC
AAGCAGCUGGUGGAAGACCUGGACCGCAUCGUGGCCUUGACCUCCAACCAGGAGUACCUGGACCUGUCCAUGCCCCU
GGACCAGUACUCCCCCAGCUUUCCCGACACCCGGAGCUCUACGUGCUCCUCAGGGGAGGAUUCCGUCUUCUCUCAUG
AGCCGCUGCCCGAGGAGCCCUGCCUGCCCCGACACCCAGCCCAGCUUGCCAAUGGCGGACUCAAACGCCGCUGACUGC
CACCCACACGCCCUCCCCAGACUCCACCGUCAGCUGUAACCCUCACCCACAGCCCCUGCUGGGCCCACCACCUGUCCG
UCCCUGUCCCCUUUCCUGCUGGCAGGAGCCGGCUGCCUACCAGGGGCCUUCCUGUGUGGCCUGCCUUCACCCCACUCA
GCUCACCUCUCCCUCCACCUCCUCUCCACCUGCUGGUGAGAGGUGCAAAGAGGCAGAUCUUUGCUGCCAGCCACUUC
AUCCCCUCCCAGAUGUUGGACCAACACCCCUCCCUGCCACCAGGCACUGCCUGGAGGGCAGGGAGUGGGAGCCAAUG
AACAGGCAUGCAAGUGAGAGCUUCCUGAGCUUUCUCCUGUCGGUUUGGUCUGUUUUGCCUUCACCCAUAAGCCCCUC
GCACUCUGGUGGCAGGUGCCUUGUCCUCAGGGCUACAGCAGUAGGGAGGUCAGUGCUUCGUGCCUCGAUUGAAGGUG
ACCUCUGCCCCAGAUAGGUGGUGCCAGUGGCUUAUUAAUUCCGAUACUAGUUUGCUUUGCUGACCAAAUGCCUGGUA
CCAGAGGAUGGUGAGGCGAAGGCCAGGUUGGGGGCAGUGUUGUGGCCCUGGGGCCCAGCCCCAAACUGGGGGCUCUG
UAUAUAGCUAUGAAGAAAACACAAAGUGUAUAAAUCUGAGUAUAUAUUUACAUGUCUUUUUAAAAGGGUCGUUACC
AGAGAUUUACCCAUCGGGUAAGAUGCUCCUGGUGGCUGGGAGGCAUCAGUUGCUAUAUAUUAAAAACAAAAAAGAA
AAAAAAGGAAAAUGUUUUUAAAAAGGUCAUAUAUUUUUUGCUACUUUUGCUGUUUUAUUUUUUUAAAUUAUGUUCU
AAACCUAUUUUCAGUUUAGGUCCCUCAAUAAAAAUUGCUGCUGCUUCAUUUAUCUAUGGGCUGUAUGAAAAGGGUG
GGAAUGUCCACUGGAAAGAAGGGACACCCACGGGCCCUGGGGCUAGGUCUGUCCCGAGGGCACCGCAUGCUCCCGGC
GCAGGUUCCUUGUAACCUCUUCUUCCUAGGUCCUGCACCCAGACCUCACGACGCACCUCCUGCCUCUCCGCUGCUUUU
GGAAAGUCAGAAAAAGAAGAUGUCUGCUUCGAGGGCAGGAACCCCAUCCAUGCAGUAGAGGCGCUGGGCAGAGAGU
741-3690

CA 02677068 2009-09-01
CAAGGCCCAGCAGCCAUCGACCAUGGAUGGUUUCCUCCAAGGAAACCGGUGGGGUUGGGCUGGGGAGGGGGCACCUA
CCUAGGAAUAGCCACGGGGUAGAGCUACAGUGAUUAAGAGGAAAGCAAGGGCGCGGUUGCUCACGCCUGUAAUCCCA
GCACUUUGGGACACCGAGGUGGGCAGAUCACUUCAGGUCAGGAGUUUGAGACCAGCCUGGCCAACUUAGUGAAACCC
CAUCUCUACUAAAAAUGCAAAAAUUAUCCAGGCAUGGUGGCACACGCCUGUAAUCCCAGCUCCACAGGAGGCUGAGG
CAGAAUCCCUUGAAGCUGGGAGGCGGAGGUUGCAGUGAGCCGAGAUUGCGCCAUUGCACUCCAGCCUGGGCAACAGA
GAAAACAAAAAGGAAAACAAAUGAUGAAGGUCUGCAGAAACUGAAACCCAGACAUGUGUCUGCCCCCUCUAUGUGG
GCAUGGUUUUGCCAGUGCUUCUAAGUGCAGGAGAACAUGUCACCUGAGGCUAGUUUUGCAUUCAGGUCCCUGGCUUC
GUUUCUUGUUGGUAUGCCUCCCCAGAUCGUCCUUCCUGUAUCCAUGUGACCAGACUGUAUUUGUUGGGACUGUCGCA
GAUCUUGGCUUCUUACAGUUCUUCCUGUCCAAACUCCAUCCUGUCCCUCAGGAACGGGGGGAAAAUUCUCCGAAUGU
UUUUGGUUUUUUGGCUGCUUGGAAUUUACUUCUGCCACCUGCUGGUCAUCACUGUCCUCACUAAGUGGAUUCUGGCU
CCCCCGUACCUCAUGGCUCAAACUACCACUCCUCAGUCGCUAUAUUAAAGCUUAUAUUUUGCUGGAUUACUGCUAAA
UACAAAAGAAAGUUCAAUAUGUUUUCAUUUCUGUAGGGAAAAUGGGAUUGCUGCUUUAAAUUUCUGAGCUAGGGAU
UUUUUGGCAGCUGCAGUGUUGGCGACUAUUGUAAAAUUCUCUUUGUUUCUCUCUGUAAAUAGCACCUGCUAACAUU
ACAAUUUGUAUUUAUGUUUAAAGAAGGCAUCAUUUGGUGAACAGAACUAGGAAAUGAAUUUUUAGCUCUUAAAAGC
AUUUGCUUUGAGACCGCACAGGAGUGUCUUUCCUUGUAAAACAGUGAUGAUAAUUUCUGCCUUGGCCCUACCUUGA
AGCAAUGUUGUGUGAAGGGAUGAAGAAUCUAAAAGUCUUCAUAAGUCCUUGGGAGAGGUGCUAGAAAAAUAUAAGG
CACUAUCAUAAUUACAGUGAUGUCCUUGCUGUUACUACUCAAAUCACCCACAAAUUUCCCCAAAGACUGCGCUAGCU
GUCAAAUAAAAGACAGUGAAAUUGACCUGAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1164;RNA;Homo sapiens>
AGAUGCAGGGGCGCAAACGCCAAAGGAGACCAGGCUGUAGGAAGAGAAGGGCAGAGCGCCGGACAGCUCG
GCCCGCUCCCCGUCCUUUGGGGCCGCGGCUGGGGAACUACAAGGCCCAGCAGGCAGCUGCAGGGGGCGGAGGCGGAG
GAGGGACCAGCGCGGGUGGGAGUGAGAGAGCGAGCCCUCGCGCCCCGCCGGCGCAUAGCGCUCGGAGCGCUCUUGCG
GCCACAGGCGCGGCGUCCUCGGCGGCGGGCGGCAGCUAGCGGGAGCCGGGACGCCGGUGCAGCCGCAGCGCGCGGAG
GAACCCGGGUGUGCCGGGAGCUGGGCGGCCACGUCCGGACGGGACCGAGACCCCUCGUAGCGCAUUGCGGCGACCUC
GCCUUCCCCGGCCGCGAGCGCGCCGCUGCUUGAAAAGCCGCGGAACCCAAGGACUUUUCUCCGGUCCGAGCUCGGGG
CGCCCCGCAGGGCGCACGGUACCCGUGCUGCAGUCGGGCACGCCGCGGCGCCGGGGCCUCCGCAGGGCGAUGGAGCCC
GGUCUGCAAGGAAAGUGAGGCGCCGCCGCUGCGUUCUGGAGGAGGGGGGCACAAGGUCUGGAGACCCCGGGUGGCGG
ACGGGAGCCCUCCCCCCGCCCCGCCUCCGGGGCACCAGCUCCGGCUCCAUUGUUCCCGCCCGGGCUGGAGGCGCCGAG
CACCGAGCGCCGCCGGGAGUCGAGCGCCGGCCGCGGAGCUCUUGCGACCCCGCCAGGACCCGAACAGAGCCCGGGGGC
GGCGGGCCGGAGCCGGGGACGCGGGCACACGCCCGCUCGCACAAGCCACGGCGGACUCUCCCGAGGCGGAACCUCCAC
GCCGAGCGAGGGUCAGUUUGAAAAGGAGGAUCGAGCUCACUGUGGAGUAUCCAUGGAGAUGUGGAGCCUUGUCACC
AACCUCUAACUGCAGAACUGGGAUGUGGAGCUGGAAGUGCCUCCUCUUCUGGGCUGUGCUGGUCACAGCCACACUCU
GCACCGCUAGGCCGUCCCCGACCUUGCCUGAACAAGCCCAGCCCUGGGGAGCCCCUGUGGAAGUGGAGUCCUUCCUG
GUCCACCCCGGUGACCUGCUGCAGCUUCGCUGUCGGCUGCGGGACGAUGUGCAGAGCAUCAACUGGCUGCGGGACGG
GGUGCAGCUGGCGGAAAGCAACCGCACCCGCAUCACAGGGGAGGAGGUGGAGGUGCAGGACUCCGUGCCCGCAGACU
CCGGCCUCUAUGCUUGCGUAACCAGCAGCCCCUCGGGCAGUGACACCACCUACUUCUCCGUCAAUGUUUCAGAUGCU
CUCCCCUCCUCGGAGGAUGAUGAUGAUGAUGAUGACUCCUCUUCAGAGGAGAAAGAAACAGAUAACACCAAACCAAA
CCGUAUGCCCGUAGCUCCAUAUUGGACAUCCCCAGAAAAGAUGGAAAAGAAAUUGCAUGCAGUGCCGGCUGCCAAGA
CAGUGAAGUUCAAAUGCCCUUCCAGUGGGACCCCAAACCCCACACUGCGCUGGUUGAAAAAUGGCAAAGAAUUCAAA
CCUGACCACAGAAUUGGAGGCUACAAGGUCCGUUAUGCCACCUGGAGCAUCAUAAUGGACUCUGUGGUGCCCUCUGA
CAAGGGCAACUACACCUGCAUUGUGGAGAAUGAGUACGGCAGCAUCAACCACACAUACCAGCUGGAUGUCGUGGAGC
GGUCCCCUCACCGGCCCAUCCUGCAAGCAGGGUUGCCCGCCAACAAAACAGUGGCCCUGGGUAGCAACGUGGAGUUC
AUGUGUAAGGUGUACAGUGACCCGCAGCCGCACAUCCAGUGGCUAAAGCACAUCGAGGUGAAUGGGAGCAAGAUUG
GCCCAGACAACCUGCCUUAUGUCCAGAUCUUGAAGACUGCUGGAGUUAAUACCACCGACAAAGAGAUGGAGGUGCUU
CACUUAAGAAAUGUCUCCUUUGAGGACGCAGGGGAGUAUACGUGCUUGGCGGGUAACUCUAUCGGACUCUCCCAUCA
CUCUGCAUGGUUGACCGUUCUGGAAGCCCUGGAAGAGAGGCCGGCAGUGAUGACCUCGCCCCUGUACCUGGAGAUCA
UCAUCUAUUGCACAGGGGCCUUCCUCAUCUCCUGCAUGGUGGGGUCGGUCAUCGUCUACAAGAUGAAGAGUGGUACC
AAGAAGAGUGACUUCCACAGCCAGAUGGCUGUGCACAAGCUGGCCAAGAGCAUCCCUCUGCGCAGACAGGUAACAGU
GUCUGCUGACUCCAGUGCAUCCAUGAACUCUGGGGUUCUUCUGGUUCGGCCAUCACGGCUCUCCUCCAGUGGGACUC
CCAUGCUAGCAGGGGUCUCUGAGUAUGAGCUUCCCGAAGACCCUCGCUGGGAGCUGCCUCGGGACAGACUGGUCUUA
GGCAAACCCCUGGGAGAGGGCUGCUUUGGGCAGGUGGUGUUGGCAGAGGCUAUCGGGCUGGACAAGGACAAACCCA
ACCGUGUGACCAAAGUGGCUGUGAAGAUGUUGAAGUCGGACGCAACAGAGAAAGACUUGUCAGACCUGAUCUCAGA
AAUGGAGAUGAUGAAGAUGAUCGGGAAGCAUAAGAAUAUCAUCAACCUGCUGGGGGCCUGCACGCAGGAUGGUCCC
UUGUAUGUCAUCGUGGAGUAUGCCUCCAAGGGCAACCUGCGGGAGUACCUGCAGGCCCGGAGGCCCCCAGGGCUGGA
AUACUGCUACAACCCCAGCCACAACCCAGAGGAGCAGCUCUCCUCCAAGGACCUGGUGUCCUGCGCCUACCAGGUGG
CCCGAGGCAUGGAGUAUCUGGCCUCCAAGAAGUGCAUACACCGAGACCUGGCAGCCAGGAAUGUCCUGGUGACAGAG
GACAAUGUGAUGAAGAUAGCAGACUUUGGCCUCGCACGGGACAUUCACCACAUCGACUACUAUAAAAAGACAACCAA
CGGCCGACUGCCUGUGAAGUGGAUGGCACCCGAGGCAUUAUUUGACCGGAUCUACACCCACCAGAGUGAUGUGUGGU
CUUUCGGGGUGCUCCUGUGGGAGAUCUUCACUCUGGGCGGCUCCCCAUACCCCGGUGUGCCUGUGGAGGAACUUUUC
AAGCUGCUGAAGGAGGGUCACCGCAUGGACAAGCCCAGUAACUGCACCAACGAGCUGUACAUGAUGAUGCGGGACUG
CUGGCAUGCAGUGCCCUCACAGAGACCCACCUUCAAGCAGCUGGUGGAAGACCUGGACCGCAUCGUGGCCUUGACCU
CCAACCAGGAGUACCUGGACCUGUCCAUGCCCCUGGACCAGUACUCCCCCAGCUUUCCCGACACCCGGAGCUCUACGU
GCUCCUCAGGGGAGGAUUCCGUCUUCUCUCAUGAGCCGCUGCCCGAGGAGCCCUGCCUGCCCCGACACCCAGCCCAGC
UUGCCAAUGGCGGACUCAAACGCCGCUGACUGCCACCCACACGCCCUCCCCAGACUCCACCGUCAGCUGUAACCCUCA
CCCACAGCCCCUGCUGGGCCCACCACCUGUCCGUCCCUGUCCCCUUUCCUGCUGGCAGGAGCCGGCUGCCUACCAGGG
GCCUUCCUGUGUGGCCUGCCUUCACCCCACUCAGCUCACCUCUCCCUCCACCUCCUCUCCACCUGCUGGUGAGAGGUG
CAAAGAGGCAGAUCUUUGCUGCCAGCCACUUCAUCCCCUCCCAGAUGUUGGACCAACACCCCUCCCUGCCACCAGGCA
CUGCCUGGAGGGCAGGGAGUGGGAGCCAAUGAACAGGCAUGCAAGUGAGAGCUUCCUGAGCUUUCUCCUGUCGGUU
UGGUCUGUUUUGCCUUCACCCAUAAGCCCCUCGCACUCUGGUGGCAGGUGCCUUGUCCUCAGGGCUACAGCAGUAGG
GAGGUCAGUGCUUCGUGCCUCGAUUGAAGGUGACCUCUGCCCCAGAUAGGUGGUGCCAGUGGCUUAUUAAUUCCGAU
ACUAGUUUGCUUUGCUGACCAAAUGCCUGGUACCAGAGGAUGGUGAGGCGAAGGCCAGGUUGGGGGCAGUGUUGUG
GCCCUGGGGCCCAGCCCCAAACUGGGGGCUCUGUAUAUAGCUAUGAAGAAAACACAAAGUGUAUAAAUCUGAGUAU
AUAUUUACAUGUCUUUUUAAAAGGGUCGUUACCAGAGAUUUACCCAUCGGGUAAGAUGCUCCUGGUGGCUGGGAGG
741-3691

CA 02677068 2009-09-01
CAUCAGUUGCUAUAUAUUAAAAACAAAAAAGAAAAAAAAGGAAAAUGUUUUUAAAAAGGUCAUAUAUUUUUUGCUA
CUUUUGCUGUUUUAUUUUUUUAAAUUAUGUUCUAAACCUAUUUUCAGUUUAGGUCCCUCAAUAAAAAUUGCUGCUG
CUUCAUUUAUCUAUGGGCUGUAUGAAAAGGGUGGGAAUGUCCACUGGAAAGAAGGGACACCCACGGGCCCUGGGGC
UAGGUCUGUCCCGAGGGCACCGCAUGCUCCCGGCGCAGGUUCCUUGUAACCUCUUCUUCCUAGGUCCUGCACCCAGA
CCUCACGACGCACCUCCUGCCUCUCCGCUGCUUUUGGAAAGUCAGAAAAAGAAGAUGUCUGCUUCGAGGGCAGGAAC
CCCAUCCAUGCAGUAGAGGCGCUGGGCAGAGAGUCAAGGCCCAGCAGCCAUCGACCAUGGAUGGUUUCCUCCAAGGA
AACCGGUGGGGUUGGGCUGGGGAGGGGGCACCUACCUAGGAAUAGCCACGGGGUAGAGCUACAGUGAUUAAGAGGA
AAGCAAGGGCGCGGUUGCUCACGCCUGUAAUCCCAGCACUUUGGGACACCGAGGUGGGCAGAUCACUUCAGGUCAGG
AGUUUGAGACCAGCCUGGCCAACUUAGUGAAACCCCAUCUCUACUAAAAAUGCAAAAAUUAUCCAGGCAUGGUGGCA
CACGCCUGUAAUCCCAGCUCCACAGGAGGCUGAGGCAGAAUCCCUUGAAGCUGGGAGGCGGAGGUUGCAGUGAGCCG
AGAUUGCGCCAUUGCACUCCAGCCUGGGCAACAGAGAAAACAAAAAGGAAAACAAAUGAUGAAGGUCUGCAGAAAC
UGAAACCCAGACAUGUGUCUGCCCCCUCUAUGUGGGCAUGGUUUUGCCAGUGCUUCUAAGUGCAGGAGAACAUGUCA
CCUGAGGCUAGUUUUGCAUUCAGGUCCCUGGCUUCGUUUCUUGUUGGUAUGCCUCCCCAGAUCGUCCUUCCUGUAUC
CAUGUGACCAGACUGUAUUUGUUGGGACUGUCGCAGAUCUUGGCUUCUUACAGUUCUUCCUGUCCAAACUCCAUCCU
GUCCCUCAGGAACGGGGGGAAAAUUCUCCGAAUGUUUUUGGUUUUUUGGCUGCUUGGAAUUUACUUCUGCCACCUG
CUGGUCAUCACUGUCCUCACUAAGUGGAUUCUGGCUCCCCCGUACCUCAUGGCUCAAACUACCACUCCUCAGUCGCU
AUAUUAAAGCUUAUAUUUUGCUGGAUUACUGCUAAAUACAAAAGAAAGUUCAAUAUGUUUUCAUUUCUGUAGGGAA
AAUGGGAUUGCUGCUUUAAAUUUCUGAGCUAGGGAUUUUUUGGCAGCUGCAGUGUUGGCGACUAUUGUAAAAUUCU
CUUUGUUUCUCUCUGUAAAUAGCACCUGCUAACAUUACAAUUUGUAUUUAUGUUUAAAGAAGGCAUCAUUUGGUGA
ACAGAACUAGGAAAUGAAUUUUUAGCUCUUAAAAGCAUUUGCUUUGAGACCGCACAGGAGUGUCUUUCCUUGUAAA
ACAGUGAUGAUAAUUUCUGCCUUGGCCCUACCUUGAAGCAAUGUUGUGUGAAGGGAUGAAGAAUCUAAAAGUCUUC
AUAAGUCCUUGGGAGAGGUGCUAGAAAAAUAUAAGGCACUAUCAUAAUUACAGUGAUGUCCUUGCUGUUACUACUC
AAAUCACCCACAAAUUUCCCCAAAGACUGCGCUAGCUGUCAAAUAAAAGACAGUGAAAUUGACCUGAAAAAAAAAA
AAAAAAA
<SEQ ID NO. 1165;RNA;Artificial Sequence> agaugcaggggcgcaaacg
<SEQ ID NO. 1166;RNA;Artificial Sequence> gccaaaggagaccaggcug
<SEQ ID NO. 1167;RNA;Artificial Sequence> guaggaagagaagggcaga
<SEQ ID NO. 1168;RNA;Artificial Sequence> agcgccggacagcucggcc
<SEQ ID NO. 1169;RNA;Artificial Sequence> ccgcuccccguccuuuggg
<SEQ ID NO. 1170;RNA;Artificial Sequence> ggccgcggcuggggaacua
<SEQ ID NO. 1171;RNA;Artificial Sequence> acaaggcccagcaggcagc
<SEQ ID NO. 1172;RNA;Artificial Sequence> cugcagggggcggaggcgg
<SEQ ID NO. 1173;RNA;Artificial Sequence> gaggagggaccagcgcggg
<SEQ ID NO. 1174;RNA;Artificial Sequence> gugggagugagagagcgag
<SEQ ID NO. 1175;RNA;Artificial Sequence> gcccucgcgccccgccggc
<SEQ ID NO. 1176;RNA;Artificial Sequences cgcauagcgcucggagcgc
<SEQ ID NO. 1177;RNA;Artificial Sequence> cucuugcggccacaggcgc
<SEQ ID NO. 1178;RNA;Artificial Sequence> cggcguccucggcggcggg
<SEQ ID NO. 1179;RNA;Artificial Sequence> gcggcagcuagcgggagcc
<SEQ ID NO. 1180;RNA;Artificial Sequence> cgggacgccggugcagccg
<SEQ ID NO. 1181;RNA;Artificial Sequence> gcagcgcgcggaggaaccc
<SEQ ID NO. 1182;RNA;Artificial Sequence> cgggugugccgggagcugg
<SEQ ID NO. 1183;RNA;Artificial Sequence> ggcggccacguccggacgg
<SEQ ID NO. 1184;RNA;Artificial Sequence> ggaccgagaccccucguag
<SEQ ID NO. 1185;RNA;Artificial Sequence> gcgcauugcggcgaccucg
<SEQ ID NO. 1186;RNA;Artificial Sequence> gccuuccccggccgcgagc
<SEQ ID NO. 1187;RNA;Artificial Sequence> cgcgccgcugcuugaaaag
<SEQ ID NO. 1188;RNA;Artificial Sequence> gccgcggaacccaaggacu
<SEQ ID NO. 1189;RNA;Artificial Sequence> uuuucuccgguccgagcuc
<SEQ ID NO. 1190;RNA;Artificial Sequence> cggggcgccccgcagggcg
<SEQ ID NO. 1191;RNA;Artificial Sequence> gcacgguacccgugcugca
<SEQ ID NO. 1192;RNA;Artificial Sequence> agucgggcacgccgcggcg
<SEQ ID NO. 11 93;RNA;Artificial Sequence> gccggggccuccgcagggc
<SEQ ID NO. 1194;RNA;Artificial Sequence> cgauggagcccggucugca
<SEQ ID NO. 1195;RNA;Artificial Sequence> aaggaaagugaggcgccgc
<SEQ ID NO. 1196;RNA;Artificial Sequence> ccgcugcguucuggaggag
<SEQ ID NO. 1197;RNA;Artificial Sequence> ggggggcacaaggucugga
<SEQ ID NO. 1198;RNA;Artificial Sequence> agaccccggguggcggacg
<SEQ ID NO. 1199;RNA;Artificial Sequence> gggagcccuccccccgccc
<SEQ ID NO. 1200;RNA;Artificial Sequence> ccgccuccggggcaccagc
<SEQ ID NO. 1201;RNA;Artificial Sequence> cuccggcuccauuguuccc
<SEQ ID NO. 1202;RNA;Artificial Sequence> cgcccgggcuggaggcgcc
<SEQ ID NO. 1203;RNA;Artificial Sequence> cgagcaccgagcgccgccg
<SEQ ID NO. 1204;RNA;Artificial Sequence> gggagucgagcgccggccg
<SEQ ID NO. 1205;RNA;Artificial Sequence> gcggagcucuugcgacccc
<SEQ ID NO. 1206;RNA;Artificial Sequence> cgccaggacccgaacagag
<SEQ ID NO. 1207;RNA;Artificial Sequence> gcccgggggcggcgggccg
<SEQ ID NO. 1208;RNA;Artificial Sequence> ggagccggggacgcgggca
<SEQ ID NO. 1209;RNA;Artificial Sequence> acacgcccgcucgcacaag
<SEQ ID NO. 1210;RNA;Artificial Sequence> gccacggcggacucucccg
<SEQ ID NO. 1211;RNA;Artificial Sequence> gaggcggaaccuccacgcc
<SEQ ID NO. 1212;RNA;Artificial Sequence> cgagcgagggucaguuuga
<SEQ ID NO. 1213;RNA;Artificial Sequence> aaaaggaggaucgagcuca
741-3692

CA 02677068 2009-09-01
<SEQ ID NO. 1214;RNA;Artificial Sequence> acuguggaguauccaugga
<SEQ ID NO. 1215;RNA;Artificial Sequence> agauguggagccuugucac
<SEQ ID NO. 1216;RNA;Artificial Sequence> ccaaccucuaacugcagaa
<SEQ ID NO. 1217;RNA;Artificial Sequence> acugggauguggagcugga
<SEQ ID NO. 1218;RNA;Artificial Sequence> aagugccuccucuucuggg
<SEQ ID NO. 1219;RNA;Artificial Sequence> gcugugcuggucacagcca
<SEQ ID NO. 1220;RNA;Artificial Sequence> acacucugcaccgcuaggc
<SEQ ID NO. 1221;RNA;Artificial Sequence> ccguccccgaccuugccug
<SEQ ID NO. 1222;RNA;Artificial Sequence> gaacaagaugcucuccccu
<SEQ ID NO. 1223;RNA;Artificial Sequence> uccucggaggaugaugaug
<SEQ ID NO. 1224;RNA;Artificial Sequence> gaugaugaugacuccucuu
<SEQ ID NO. 1225;RNA;Artificial Sequence> ucagaggagaaagaaacag
<SEQ ID NO. 1226;RNA;Artificial Sequence> gauaacaccaaaccaaacc
<SEQ ID NO. 1227;RNA;Artificial Sequence> cccguagcuccauauugga
<SEQ ID NO. 1228;RNA;Artificial Sequence> acauccccagaaaagaugg
<SEQ ID NO. 1229;RNA;Artificial Sequence> gaaaagaaauugcaugcag
<SEQ ID NO. 1230;RNA;Artificial Sequence> gugccggcugccaagacag
<SEQ ID NO. 1231;RNA;Artificial Sequence> gugaaguucaaaugcccuu
<SEQ ID NO. 1232;RNA;Artificial Sequence> uccagugggaccccaaacc
<SEQ ID NO. 1233;RNA;Artificial Sequence> cccacacugcgcugguuga
<SEQ ID NO. 1234;RNA;Artificial Sequence> aaaaauggcaaagaauuca
<SEQ ID NO. 1235;RNA;Artificial Sequence> aaaccugaccacagaauug
<SEQ ID NO. 1236;RNA;Artificial Sequence> ggaggcuacaagguccguu
<SEQ ID NO. 1237;RNA;Artificial Sequence> uaugccaccuggagcauca
<SEQ ID NO. 1238;RNA;Artificial Sequence> auaauggacucuguggugc
<SEQ ID NO. 1239;RNA;Artificial Sequence> cccucugacaagggcaacu
<SEQ ID NO. 1240;RNA;Artificial Sequence> uacaccugcauuguggaga
<SEQ ID NO. 1241;RNA;Artificial Sequence> aaugaguacggcagcauca
<SEQ ID NO. 1242;RNA;Artificial Sequence> aaccacacauaccagcugg
<SEQ ID NO. 1243;RNA;Artificial Sequence> gaugucguggagcgguccc
<SEQ ID NO. 1244;RNA;Artificial Sequence> ccucaccggcccauccugc
<SEQ ID NO. 1245;RNA;Artificial Sequence> caagcaggguugcccgcca
<SEQ ID NO. 1246;RNA;Artificial Sequence> aacaaaacaguggcccugg
<SEQ ID NO. 1247;RNA;Artificial Sequence> gguagcaacguggaguuca
<SEQ ID NO. 1248;RNA;Artificial Sequence> auguguaagguguacagug
<SEQ ID NO. 1249;RNA;Artificial Sequence> gacccgcagccgcacaucc
<SEQ ID NO. 1250;RNA;Artificial Sequence> caguggcuaaagcacaucg
<SEQ ID NO. 1251;RNA;Artificial Sequence> gaggugaaugggagcaaga
<SEQ ID NO. 1252;RNA;Artificial Sequence> auuggcccagacaaccugc
<SEQ ID NO. 1253;RNA;Artificial Sequence> ccuuauguccagaucuuga
<SEQ ID NO. 1254;RNA;Artificial Sequence> aagacugcuggaguuaaua
<SEQ ID NO. 1255;RNA;Artificial Sequence> accaccgacaaagagaugg
<SEQ ID NO. 1256;RNA;Artificial Sequence> gaggugcuucacuuaagaa
<SEQ ID NO. 1257;RNA;Artificial Sequence> aaugucuccuuugaggacg
<SEQ ID NO. 1258;RNA;Artificial Sequence> gcaggggaguauacgugcu
<SEQ ID NO. 1259;RNA;Artificial Sequence> uuggcggguaacucuaucg
<SEQ ID NO. 1260;RNA;Artificial Sequence> ggacucucccaucacucug
<SEQ ID NO. 1261;RNA;Artificial Sequence> gcaugguugaccguucugg
<SEQ ID NO. 1262;RNA;Artificial Sequence> gaagcccuggaagagaggc
<SEQ ID NO. 1263;RNA;Artificial Sequence> ccggcagugaugaccucgc
<SEQ ID NO. 1264;RNA;Artificial Sequence> ccccuguaccuggagauca
<SEQ ID NO. 1265;RNA;Artificial Sequence> aucaucuauugcacagggg
<SEQ ID NO. 1266;RNA;Artificial Sequence> gccuuccucaucuccugca
<SEQ ID NO. 1267;RNA;Artificial Sequence> augguggggucggucaucg
<SEQ ID NO. 1268;RNA;Artificial Sequence> gucuacaagaugaagagug
<SEQ ID NO. 1269;RNA;Artificial Sequence> gguaccaagaagagugacu
<SEQ ID NO. 1270;RNA;Artificial Sequence> uuccacagccagauggcug
<SEQ ID NO. 1271;RNA;Artificial Sequence> gugcacaagcuggccaaga
<SEQ ID NO. 1272;RNA;Artificial Sequence> agcaucccucugcgcagac
<SEQ ID NO. 1273;RNA;Artificial Sequence> cagguaacagugucugcug
<SEQ ID NO. 1274;RNA;Artificial Sequence> gacuccagugcauccauga
<SEQ ID NO. 1275;RNA;Artificial Sequence> aacucugggguucuucugg
<SEQ ID NO. 1276;RNA;Artificial Sequence> guucggccaucacggcucu
<SEQ ID NO. 1277;RNA;Artificial Sequence> uccuccagugggacuccca
<SEQ ID NO. 1278;RNA;Artificial Sequence> augcuagcaggggucucug
<SEQ ID NO. 1279;RNA;Artificial Sequence> gaguaugagcuucccgaag
<SEQ ID NO. 1280;RNA;Artificial Sequence> gacccucgcugggagcugc
<SEQ ID NO. 1281;RNA;Artificial Sequence> ccucgggacagacuggucu
<SEQ ID NO. 1282;RNA;Artificial Sequence> uuaggcaaaccccugggag
<SEQ ID NO. 1283;RNA;Artificial Sequence> gagggcugcuuugggcagg
<SEQ ID NO. I284;RNA;Artificial Sequence> gugguguuggcagaggcua
<SEQ ID NO. 1285;RNA;Artificial Sequence> aucgggcuggacaaggaca
<SEQ ID NO. 1286;RNA;Artificial Sequence> aaacccaaccgugugacca
741-3693

CA 02677068 2009-09-01
<SEQ ID NO. 1287;RNA;Artificial Sequence> aaaguggcugugaagaugu
<SEQ ID NO. 1288;RNA;Artificial Sequence> uugaagucggacgcaacag
<SEQ ID NO. 1289;RNA;Artificial Sequence> gagaaagacuugucagacc
<SEQ ID NO. 1290;RNA;Artificial Sequence> cugaucucagaaauggaga
<SEQ ID NO. 1291;RNA;Artificial Sequence> augaugaagaugaucggga
<SEQ ID NO. 1292;RNA;Artificial Sequence> aagcauaagaauaucauca
<SEQ ID NO. 1293;RNA;Artificial Sequence> aaccugcugggggccugca
<SEQ ID NO. 1294;RNA;Artificial Sequence> acgcaggauggucccuugu
<SEQ ID NO. 1295;RNA;Artificial Sequence> uaugucaucguggaguaug
<SEQ ID NO. 1296;RNA;Artificial Sequence> gccuccaagggcaaccugc
<SEQ ID NO. 1297;RNA;Artificial Sequence> cgggaguaccugcaggccc
<SEQ ID NO. 1298;RNA;Artificial Sequence> cggaggcccccagggcugg
<SEQ ID NO. 1299;RNA;Artificial Sequence> gaauacugcuacaacccca
<SEQ ID NO. 1300;RNA;Artificial Sequence> agccacaacccagaggagc
<SEQ ID NO. 1301;RNA;Artificial Sequence> cagcucuccuccaaggacc
<SEQ ID NO. 1302;RNA;Artificial Sequence> cugguguccugcgccuacc
<SEQ ID NO. 1303;RNA;Artificial Sequence> cagguggcccgaggcaugg
<SEQ ID NO. 1304;RNA;Artificial Sequence> gaguaucuggccuccaaga
<SEQ ID NO. 1305;RNA;Artificial Sequence> aagugcauacaccgagacc
<SEQ ID NO. 1306;RNA;Artificial Sequence> cuggcagccaggaaugucc
<SEQ ID NO. 1307;RNA;Artificial Sequence> cuggugacagaggacaaug
<SEQ ID NO. 1308;RNA;Artificial Sequence> gugaugaagauagcagacu
<SEQ ID NO. 1309;RNA;Artificial Sequence> uuuggccucgcacgggaca
<SEQ ID NO. 1310;RNA;Artificial Sequence> auucaccacaucgacuacu
<SEQ ID NO. 1311;RNA;Artificial Sequence> uauaaaaagacaaccaacg
<SEQ ID NO. 1312;RNA;Artificial Sequence> ggccgacugccugugaagu
<SEQ ID NO. 1313;RNA;Artificial Sequence> uggauggcacccgaggcau
<SEQ ID NO. 1314;RNA;Artificial Sequence> uuauuugaccggaucuaca
<SEQ ID NO. 1315;RNA;Artificial Sequence> acccaccagagugaugugu
<SEQ ID NO. 1316;RNA;Artificial Sequence> uggucuuucggggugcucc
<SEQ ID NO. 1317;RNA;Artificial Sequence> cugugggagaucuucacuc
<SEQ ID NO. 1318;RNA;Artificial Sequence> cugggcggcuccccauacc
<SEQ ID NO. 1319;RNA;Artificial Sequence> cccggugugccuguggagg
<SEQ ID NO. 1320;RNA;Artificial Sequence> gaacuuuucaagcugcuga
<SEQ ID NO. 1321;RNA;Artificial Sequence> aaggagggucaccgcaugg
<SEQ ID NO. 1322;RNA;Artificial Sequence> gacaagcccaguaacugca
<SEQ ID NO. 1323;RNA;Artificial Sequence> accaacgagcuguacauga
<SEQ ID NO. 1324;RNA;Artificial Sequence> augaugcgggacugcuggc
<SEQ ID NO. 1325;RNA;Artificial Sequence> caugcagugcccucacaga
<SEQ ID NO. 1326;RNA;Artificial Sequence> agacccaccuucaagcagc
<SEQ ID NO. 1327;RNA;Artificial Sequence> cugguggaagaccuggacc
<SEQ ID NO. 1328;RNA;Artificial Sequence> cgcaucguggccuugaccu
<SEQ ID NO. 1329;RNA;Artificial Sequence> uccaaccaggaguaccugg
<SEQ ID NO. 1330;RNA;Artificial Sequence> gaccuguccaugccccugg
<SEQ ID NO. 1331;RNA;Artificial Sequence> gaccaguacucccccagcu
<SEQ ID NO. 1332;RNA;Artificial Sequence> uuucccgacacccggagcu
<SEQ ID NO. 1333;RNA;Artificial Sequence> ucuacgugcuccucagggg
<SEQ ID NO. 1334;RNA;Artificial Sequence> gaggauuccgucuucucuc
<SEQ ID NO. 1335;RNA;Artificial Sequence> caugagccgcugcccgagg
<SEQ ID NO. 1336;RNA;Artificial Sequence> gagcccugccugccccgac
<SEQ ID NO. 1337;RNA;Artificial Sequence> cacccagcccagcuugcca
<SEQ ID NO. 1338;RNA;Artificial Sequence> aauggcggacucaaacgcc
<SEQ ID NO. 1339;RNA;Artificial Sequence> cgcugacugccacccacac
<SEQ ID NO. 1340;RNA;Artificial Sequence> cgcccuccccagacuccac
<SEQ ID NO. 1341;RNA;Artificial Sequence> ccgucagcuguaacccuca
<SEQ ID NO. 1342;RNA;Artificial Sequence> acccacagccccugcuggg
<SEQ ID NO. 1343;RNA;Artificial Sequence> gcccaccaccuguccgucc
<SEQ ID NO. 1344;RNA;Artificial Sequence> ccuguccccuuuccugcug
<SEQ ID NO. 1345;RNA;Artificial Sequence> ggcaggagccggcugccua
<SEQ ID NO. 1346;RNA;Artificial Sequence> accaggggccuuccugugu
<SEQ ID NO. 1347;RNA;Artificial Sequence> uggccugccuucaccccac
<SEQ ID NO. 1348;RNA;Artificial Sequence> cucagcucaccucucccuc
<SEQ ID NO. I349;RNA;Artificial Sequence> ccaccuccucuccaccugc
<SEQ ID NO. 1350;RNA;Artificial Sequence> cuggugagaggugcaaaga
<SEQ ID NO. 1351;RNA;Artificial Sequence> aggcagaucuuugcugcca
<SEQ ID NO. 1352;RNA;Artificial Sequence> agccacuucauccccuccc
<SEQ ID NO. 1353;RNA;Artificial Sequence> cagauguuggaccaacacc
<SEQ ID NO. 1354;RNA;Artificial Sequence> cccucccugccaccaggca
<SEQ ID NO. 1355;RNA;Artificial Sequence> acugccuggagggcaggga
<SEQ ID NO. 1356;RNA;Artificial Sequence> agugggagccaaugaacag
<SEQ ID NO. 1357;RNA;Artificial Sequence> ggcaugcaagugagagcuu
<SEQ ID NO. 1358;RNA;Artificial Sequence> uccugagcuuucuccuguc
<SEQ ID NO. I359;RNA;Artificial Sequence> cgguuuggucuguuuugcc
741-3694

CA 02677068 2009-09-01
<SEQ ID NO. 1360;RNA;Artificial Sequence> cuucacccauaagccccuc
<SEQ ID NO. 1361;RNA;Artificial Sequence> cgcacucugguggcaggug
<SEQ ID NO. 1362;RNA;Artificial Sequence> gccuuguccucagggcuac
<SEQ ID NO. 1363;RNA;Artificial Sequence> cagcaguagggaggucagu
<SEQ ID NO. 1364;RNA;Artificial Sequence> ugcuucgugccucgauuga
<SEQ ID NO. 1365;RNA;Artificial Sequence> aaggugaccucugccccag
<SEQ ID NO. 1366;RNA;Artificial Sequence> gauagguggugccaguggc
<SEQ ID NO. 1367;RNA;Artificial Sequence> cuuauuaauuccgauacua
<SEQ ID NO. 1368;RNA;Artificial Sequence> aguuugcuuugcugaccaa
<SEQ ID NO. 1369;RNA;Artificial Sequence> aaugccugguaccagagga
<SEQ ID NO. I370;RNA;Artificial Sequence> auggugaggcgaaggccag
<SEQ ID NO. 1371;RNA;Artificial Sequence> gguugggggcaguguugug
<SEQ ID NO. 1372;RNA;Artificial Sequence> ggcccuggggcccagcccc
<SEQ ID NO. 1373;RNA;Artificial Sequence> caaacugggggcucuguau
<SEQ ID NO. 1374;RNA;Artificial Sequence> uauagcuaugaagaaaaca
<SEQ ID NO. 1375;RNA;Artificial Sequence> acaaaguguauaaaucuga
<SEQ ID NO. 1376;RNA;Artificial Sequence> aguauauauuuacaugucu
<SEQ ID NO. 1377;RNA;Artificial Sequence> uuuuuaaaagggucguuac
<SEQ ID NO. 1378;RNA;Artificial Sequence> ccagagauuuacccaucgg
<SEQ ID NO. 1379;RNA;Artificial Sequence> gguaagaugcuccuggugg
<SEQ ID NO. 1380;RNA;Artificial Sequence> gcugggaggcaucaguugc
<SEQ ID NO. 1381;RNA;Artificial Sequence> cuauauauuaaaaacaaaa
<SEQ ID NO. 1382;RNA;Artificial Sequence> aaagaaaaaaaaggaaaau
<SEQ ID NO. 1383;RNA;Artificial Sequence> uguuuuuaaaaaggucaua
<SEQ ID NO. 1384;RNA;Artificial Sequence> auauuuuuugcuacuuuug
<SEQ ID NO. 1385;RNA;Artificial Sequence> gcuguuuuauuuuuuuaaa
<SEQ ID NO. 1386;RNA;Artificial Sequence> auuauguucuaaaccuauu
<SEQ ID NO. 1387;RNA;Artificial Sequence> uuucaguuuaggucccuca
<SEQ ID NO. 1388;RNA;Artificial Sequence> aauaaaaauugcugcugcu
<SEQ ID NO. 1389;RNA;Artificial Sequence> uucauuuaucuaugggcug
<SEQ ID NO. 1390;RNA;Artificial Sequence> guaugaaaagggugggaau
<SEQ ID NO. 1391;RNA;Artificial Sequence> uguccacuggaaagaaggg
<SEQ ID NO. 1392;RNA;Artificial Sequence> gacacccacgggcccuggg
<SEQ ID NO. 1393;RNA;Artificial Sequence> ggcuaggucugucccgagg
<SEQ ID NO. 1394;RNA;Artificial Sequence> ggcaccgcaugcucccggc
<SEQ ID NO. 1395;RNA;Artificial Sequence> cgcagguuccuuguaaccu
<SEQ ID NO. 1396;RNA;Artificial Sequence> ucuucuuccuagguccugc
<SEQ ID NO. 1397;RNA;Artificial Sequence> cacccagaccucacgacgc
<SEQ ID NO. 1398;RNA;Artificial Sequence> caccuccugccucuccgcu
<SEQ ID NO. 1399;RNA;Artificial Sequence> ugcuuuuggaaagucagaa
<SEQ ID NO. 1400;RNA;Artificial Sequence> aaaagaagaugucugcuuc
<SEQ ID NO. 1401;RNA;Artificial Sequence> cgagggcaggaaccccauc
<SEQ ID NO. 1402;RNA;Artificial Sequence> ccaugcaguagaggcgcug
<SEQ ID NO. 1403;RNA;Artificial Sequence> gggcagagagucaaggccc
<SEQ ID NO. 1404;RNA;Artificial Sequence> cagcagccaucgaccaugg
<SEQ ID NO. 1405;RNA;Artificial Sequence> gaugguuuccuccaaggaa
<SEQ ID NO. 1406;RNA;Artificial Sequence> aaccggugggguugggcug
<SEQ ID NO. 1407;RNA;Artificial Sequence> ggggagggggcaccuaccu
<SEQ ID NO. 1408;RNA;Artificial Sequence> uaggaauagccacggggua
<SEQ ID NO. I409;RNA;Artificial Sequence> agagcuacagugauuaaga
<SEQ ID NO. 1410;RNA;Artificial Sequence> aggaaagcaagggcgcggu
<SEQ ID NO. 1411;RNA;Artificial Sequence> uugcucacgccuguaaucc
<SEQ ID NO. 1412;RNA;Artificial Sequence> ccagcacuuugggacaccg
<SEQ ID NO. 1413;RNA;Artificial Sequence> gaggugggcagaucacuuc
<SEQ ID NO. 1414;RNA;Artificial Sequence> caggucaggaguuugagac
<SEQ ID NO. 1415;RNA;Artificial Sequence> ccagccuggccaacuuagu
<SEQ ID NO. 1416;RNA;Artificial Sequence> ugaaaccccaucucuacua
<SEQ ID NO. 1417;RNA;Artificial Sequence> aaaaaugcaaaaauuaucc
<SEQ ID NO. 1418;RNA;Artificial Sequence> caggcaugguggcacacgc
<SEQ ID NO. 1419;RNA;Artificial Sequence> ccuguaaucccagcuccac
<SEQ ID NO. 1420;RNA;Artificial Sequence> caggaggcugaggcagaau
<SEQ ID NO. 1421;RNA;Artificial Sequence> ucccuugaagcugggaggc
<SEQ ID NO. 1422;RNA;Artificial Sequence> cggagguugcagugagccg
<SEQ ID NO. 1423;RNA;Artificial Sequence> gagauugcgccauugcacu
<SEQ ID NO. 1424;RNA;Artificial Sequence> uccagccugggcaacagag
<SEQ ID NO. 1425;RNA;Artificial Sequence> gaaaacaaaaaggaaaaca
<SEQ ID NO. 1426;RNA;Artificial Sequence> aaaugaugaaggucugcag
<SEQ ID NO. 1427;RNA;Artificial Sequence> gaaacugaaacccagacau
<SEQ ID NO. 1428;RNA;Artificial Sequence> ugugucugcccccucuaug
<SEQ ID NO. 1429;RNA;Artificial Sequence> gugggcaugguuuugccag
<SEQ ID NO. 1430;RNA;Artificial Sequence> gugcuucuaagugcaggag
<SEQ ID NO. 1431;RNA;Artificial Sequence> gaacaugucaccugaggcu
<SEQ ID NO. 1432;RNA;Artificial Sequence> uaguuuugcauucaggucc
741-3695

CA 02677068 2009-09-01
<SEQ ID NO. 1433;RNA;Artificial Sequence> ccuggcuucguuucuuguu
<SEQ ID NO. 1434;RNA;Artificial Sequence> ugguaugccuccccagauc
<SEQ ID NO. 1435;RNA;Artificial Sequence> cguccuuccuguauccaug
<SEQ ID NO. 1436;RNA;Artificial Sequence> gugaccagacuguauuugu
<SEQ ID NO. 1437;RNA;Artificial Sequence> uugggacugucgcagaucu
<SEQ ID NO. 1438;RNA;Artificial Sequence> uuggcuucuuacaguucuu
<SEQ ID NO. 1439;RNA;Artificial Sequence> uccuguccaaacuccaucc
<SEQ ID NO. 1440;RNA;Artificial Sequence> cugucccucaggaacgggg
<SEQ ID NO. 1441;RNA;Artificial Sequence> gggaaaauucuccgaaugu
<SEQ ID NO. 1442;RNA;Artificial Sequence> uuuuugguuuuuuggcugc
<SEQ ID NO. 1443;RNA;Artificial Sequence> cuuggaauuuacuucugcc
<SEQ ID NO. 1444;RNA;Artificial Sequence> caccugcuggucaucacug
<SEQ ID NO. 1445;RNA;Artificial Sequence> guccucacuaaguggauuc
<SEQ ID NO. 1446;RNA;Artificial Sequence> cuggcucccccguaccuca
<SEQ ID NO. 1447;RNA;Artificial Sequence> auggcucaaacuaccacuc
<SEQ ID NO. 1448;RNA;Artificial Sequence> ccucagucgcuauauuaaa
<SEQ ID NO. 1449;RNA;Artificial Sequence> agcuuauauuuugcuggau
<SEQ ID NO. 1450;RNA;Artificial Sequence> uuacugcuaaauacaaaag
<SEQ ID NO. 1451;RNA;Artificial Sequence> gaaaguucaauauguuuuc
<SEQ ID NO. 1452;RNA;Artificial Sequence> cauuucuguagggaaaaug
<SEQ ID NO. 1453;RNA;Artificial Sequence> gggauugcugcuuuaaauu
<SEQ ID NO. 1454;RNA;Artificial Sequence> uucugagcuagggauuuuu
<SEQ ID NO. 1455;RNA;Artificial Sequence> uuggcagcugcaguguugg
<SEQ ID NO. 1456;RNA;Artificial Sequence> gcgacuauuguaaaauucu
<SEQ ID NO. 1457;RNA;Artificial Sequence> ucuuuguuucucucuguaa
<SEQ ID NO. 1458;RNA;Artificial Sequence> aauagcaccugcuaacauu
<SEQ ID NO. 1459;RNA;Artificial Sequence> uacaauuuguauuuauguu
<SEQ ID NO. 1460;RNA;Artificial Sequence> uuaaagaaggcaucauuug
<SEQ ID NO. 1461;RNA;Artificial Sequence> ggugaacagaacuaggaaa
<SEQ ID NO. 1462;RNA;Artificial Sequence> augaauuuuuagcucuuaa
<SEQ ID NO. 1463;RNA;Artificial Sequence> aaagcauuugcuuugagac
<SEQ ID NO. 1464;RNA;Artificial Sequence> ccgcacaggagugucuuuc
<SEQ ID NO. 1465;RNA;Artificial Sequence> ccuuguaaaacagugauga
<SEQ ID NO. 1466;RNA;Artificial Sequence> auaauuucugccuuggccc
<SEQ ID NO. 1467;RNA;Artificial Sequence> cuaccuugaagcaauguug
<SEQ ID NO. 1468;RNA;Artificial Sequence> gugugaagggaugaagaau
<SEQ ID NO. 1469;RNA;Artificial Sequence> ucuaaaagucuucauaagu
<SEQ ID NO. 1470;RNA;Artificial Sequence> uccuugggagaggugcuag
<SEQ ID NO. 1471;RNA;Artificial Sequence> gaaaaauauaaggcacuau
<SEQ ID NO. 1472;RNA;Artificial Sequence> ucauaauuacagugauguc
<SEQ ID NO. 1473;RNA;Artificial Sequence> ccuugcuguuacuacucaa
<SEQ ID NO. 1474;RNA;Artificial Sequence> aaucacccacaaauuuccc
<SEQ ID NO. 1475;RNA;Artificial Sequence> ccaaagacugcgcuagcug
<SEQ ID NO. 1476;RNA;Artificial Sequence> gucaaauaaaagacaguga
<SEQ ID NO. 1477;RNA;Artificial Sequence> aaauugaccugaaaaaaaa
<SEQ ID NO. 1478;RNA;Artificial Sequence> gaacaagcccagcccuggg
<SEQ ID NO. 1479;RNA;Artificial Sequence> ggagccccuguggaagugg
<SEQ ID NO. 1480;RNA;Artificial Sequence> gaguccuuccugguccacc
<SEQ ID NO. 1481;RNA;Artificial Sequence> cccggugaccugcugcagc
<SEQ ID NO. 1482;RNA;Artificial Sequence> cuucgcugucggcugcggg
<SEQ ID NO. 1483;RNA;Artificial Sequence> gacgaugugcagagcauca
<SEQ ID NO. 1484;RNA;Artificial Sequence> aacuggcugcgggacgggg
<SEQ ID NO. 1485;RNA;Artificial Sequence> gugcagcuggcggaaagca
<SEQ ID NO. 1486;RNA;Artificial Sequence> aaccgcacccgcaucacag
<SEQ ID NO. 1487;RNA;Artificial Sequence> ggggaggagguggaggugc
<SEQ ID NO. 1488;RNA;Artificial Sequence> caggacuccgugcccgcag
<SEQ ID NO. 1489;RNA;Artificial Sequence> gacuccggccucuaugcuu
<SEQ ID NO. 1490;RNA;Artificial Sequence> ugcguaaccagcagccccu
<SEQ ID NO. 1491;RNA;Artificial Sequence> ucgggcagugacaccaccu
<SEQ ID NO. 1492;RNA;Artificial Sequence> uacuucuccgucaauguuu
<SEQ ID NO. 1493;RNA;Artificial Sequence> ucagaugcucuccccuccu
<SEQ ID NO. 1494;RNA;Artificial Sequence> ucggaggaugaugaugaug
<SEQ ID NO. 1495;RNA;Artificial Sequence> gaugaugacuccucuucag
<SEQ ID NO. 1496;RNA;Artificial Sequence> gaggagaaagaaacagaua
<SEQ ID NO. 1497;RNA;Artificial Sequence> aacaccaaaccaaaccccg
<SEQ ID NO. 1498;RNA;Artificial Sequence> guagcuccauauuggacau
<SEQ ID NO. 1499;RNA;Artificial Sequence> uccccagaaaagauggaaa
<SEQ ID NO. 1500;RNA;Artificial Sequence> aagaaauugcaugcagugc
<SEQ ID NO. 1501;RNA;Artificial Sequence> ccggcugccaagacaguga
<SEQ ID NO. 1502;RNA;Artificial Sequence> aaguucaaaugcccuucca
<SEQ ID NO. 1503;RNA;Artificial Sequence> agugggaccccaaacccca
<SEQ ID NO. 1504;RNA;Artificial Sequence> acacugcgcugguugaaaa
<SEQ ID NO. 1505;RNA;Anificial Sequence> aauggcaaagaauucaaac
741-3696

CA 02677068 2009-09-01
<SEQ ID NO. 1506;RNA;Artificial Sequence> ccugaccacagaauuggag
<SEQ ID NO. 1507;RNA;Artificial Sequence> ggcuacaagguccguuaug
<SEQ ID NO. 1508;RNA;Artificial Sequence> gccaccuggagcaucauaa
<SEQ ID NO. 1509;RNA;Artificial Sequence> auggacucuguggugcccu
<SEQ ID NO. 1510;RNA;Artificial Sequence> ucugacaagggcaacuaca
<SEQ ID NO. 1511;RNA;Artificial Sequence> accugcauuguggagaaug
<SEQ ID NO. 1512;RNA;Artificial Sequence> gaguacggcagcaucaacc
<SEQ ID NO. 1513;RNA;Artificial Sequence> cacacauaccagcuggaug
<SEQ ID NO. 1514;RNA;Artificial Sequence> gucguggagcgguccccuc
<SEQ ID NO. 1515;RNA;Artificial Sequence> caccggcccauccugcaag
<SEQ ID NO. 1516;RNA;Artificial Sequence> gcaggguugcccgccaaca
<SEQ ID NO. 1517;RNA;Artificial Sequence> aaaacaguggcccugggua
<SEQ ID NO. 1518;RNA;Artificial Sequence> agcaacguggaguucaugu
<SEQ ID NO. 1519;RNA;Artificial Sequence> uguaagguguacagugacc
<SEQ ID NO. 1520;RNA;Artificial Sequence> ccgcagccgcacauccagu
<SEQ ID NO. 1521;RNA;Artificial Sequence> uggcuaaagcacaucgagg
<SEQ ID NO. 1522;RNA;Artificial Sequence> gugaaugggagcaagauug
<SEQ ID NO. 1523;RNA;Artificial Sequence> ggcccagacaaccugccuu
<SEQ ID NO. 1524;RNA;Artificial Sequence> uauguccagaucuugaaga
<SEQ ID NO. 1525;RNA;Artificial Sequence> acugcuggaguuaauacca
<SEQ ID NO. 1526;RNA;Artificial Sequence> accgacaaagagauggagg
<SEQ ID NO. 1527;RNA;Artificial Sequence> gugcuucacuuaagaaaug
<SEQ ID NO. 1528;RNA;Artificial Sequence> gucuccuuugaggacgcag
<SEQ ID NO. 1529;RNA;Artificial Sequence> ggggaguauacgugcuugg
<SEQ ID NO. 1530;RNA;Artificial Sequence> gcggguaacucuaucggac
<SEQ ID NO. 1531;RNA;Artificial Sequence> cucucccaucacucugcau
<SEQ ID NO. 1532;RNA;Artificial Sequence> ugguugaccguucuggaag
<SEQ ID NO. 1533;RNA;Artificial Sequence> gcccuggaagagaggccgg
<SEQ ID NO. 1534;RNA;Artificial Sequence> gcagugaugaccucgcccc
<SEQ ID NO. 1535;RNA;Artificial Sequence> cuguaccuggagaucauca
<SEQ ID NO. 1536;RNA;Artificial Sequence> aucuauugcacaggggccu
<SEQ ID NO. 1537;RNA;Artificial Sequence> uuccucaucuccugcaugg
<SEQ ID NO. 1538;RNA;Artificial Sequence> guggggucggucaucgucu
<SEQ ID NO. 1539;RNA;Artificial Sequence> uacaagaugaagaguggua
<SEQ ID NO. 1540;RNA;Artificial Sequence> accaagaagagugacuucc
<SEQ ID NO. 1541;RNA;Artificial Sequence> cacagccagauggcugugc
<SEQ ID NO. 1542;RNA;Artificial Sequence> cacaagcuggccaagagca
<SEQ ID NO. 1543;RNA;Artificial Sequence> aucccucugcgcagacagg
<SEQ ID NO. 1544;RNA;Artificial Sequence> guaacagugucugcugacu
<SEQ ID NO. 1545;RNA;Artificial Sequence> uccagugcauccaugaacu
<SEQ ID NO. 1546;RNA;Artificial Sequence> ucugggguucuucugguuc
<SEQ ID NO. 1547;RNA;Artificial Sequence> cggccaucacggcucuccu
<SEQ ID NO. 1548;RNA;Artificial Sequence> uccagugggacucccaugc
<SEQ ID NO. 1549;RNA;Artificial Sequence> cuagcaggggucucugagu
<SEQ ID NO. 1550;RNA;Artificial Sequence> uaugagcuucccgaagacc
<SEQ ID NO. 1551;RNA;Artificial Sequence> ccucgcugggagcugccuc
<SEQ ID NO. 1552;RNA;Artificial Sequence> cgggacagacuggucuuag
<SEQ ID NO. 1553;RNA;Artificial Sequence> ggcaaaccccugggagagg
<SEQ ID NO. 1554;RNA;Artificial Sequence> ggcugcuuugggcaggugg
<SEQ ID NO. 1555;RNA;Artificial Sequence> guguuggcagaggcuaucg
<SEQ ID NO. 1556;RNA;Artificial Sequence> gggcuggacaaggacaaac
<SEQ ID NO. 1557;RNA;Artificial Sequence> cccaaccgugugaccaaag
<SEQ ID NO. 1558;RNA;Artificial Sequence> guggcugugaagauguuga
<SEQ ID NO. 1559;RNA;Artificial Sequence> aagucggacgcaacagaga
<SEQ ID NO. 1560;RNA;Artificial Sequence> aaagacuugucagaccuga
<SEQ ID NO. 1561;RNA;Artificial Sequence> aucucagaaauggagauga
<SEQ ID NO. 1562;RNA;Artificial Sequence> augaagaugaucgggaagc
<SEQ ID NO. 1563;RNA;Artificial Sequence> cauaagaauaucaucaacc
<SEQ ID NO. 1564;RNA;Artificial Sequence> cugcugggggccugcacgc
<SEQ ID NO. 1565;RNA;Artificial Sequence> caggauggucccuuguaug
<SEQ ID NO. 1566;RNA;Artificial Sequence> gucaucguggaguaugccu
<SEQ ID NO. 1567;RNA;Artificial Sequence> uccaagggcaaccugcggg
<SEQ ID NO. 1568;RNA;Artificial Sequence> gaguaccugcaggcccgga
<SEQ ID NO. 1569;RNA;Artificial Sequence> aggcccccagggcuggaau
<SEQ ID NO. 1570;RNA;Artificial Sequence> uacugcuacaaccccagcc
<SEQ ID NO. 1571;RNA;Artificial Sequence> cacaacccagaggagcagc
<SEQ ID NO. 1572;RNA;Artificial Sequence> cucuccuccaaggaccugg
<SEQ ID NO. 1573;RNA;Artificial Sequence> guguccugcgccuaccagg
<SEQ ID NO. 1574;RNA;Artificial Sequence> guggcccgaggcauggagu
<SEQ ID NO. 1575;RNA;Artificial Sequence> uaucuggccuccaagaagu
<SEQ ID NO. 1576;RNA;Artificial Sequence> ugcauacaccgagaccugg
<SEQ ID NO. 1577;RNA;Artificial Sequence> gcagccaggaauguccugg
<SEQ ID NO. 1578;RNA;Artificial Sequence> gugacagaggacaauguga
741-3697

CA 02677068 2009-09-01
<SEQ ID NO. 1579;RNA;Artificial Sequence> augaagauagcagacuuug
<SEQ ID NO. 1580;RNA;Artificial Sequence> ggccucgcacgggacauuc
<SEQ ID NO. 1581;RNA;Artificial Sequence> caccacaucgacuacuaua
<SEQ ID NO. 1582;RNA;Artificial Sequence> aaaaagacaaccaacggcc
<SEQ ID NO. 1583;RNA;Artificial Sequence> cgacugccugugaagugga
<SEQ ID NO. 1584;RNA;Artificial Sequence> auggcacccgaggcauuau
<SEQ ID NO. 1585;RNA;Artificial Sequence> uuugaccggaucuacaccc
<SEQ ID NO. 1586;RNA;Artificial Sequence> caccagagugauguguggu
<SEQ ID NO. 1587;RNA;Artificial Sequence> ucuuucggggugcuccugu
<SEQ ID NO. 1588;RNA;Artificial Sequence> ugggagaucuucacucugg
<SEQ ID NO. 1589;RNA;Artificial Sequence> ggcggcuccccauaccccg
<SEQ ID NO. 1590;RNA;Artificial Sequence> ggugugccuguggaggaac
<SEQ ID NO. 1591;RNA;Artificial Sequence> cuuuucaagcugcugaagg
<SEQ ID NO. 1592;RNA;Artificial Sequence> gagggucaccgcauggaca
<SEQ ID NO. 1593;RNA;Artificial Sequence> aagcccaguaacugcacca
<SEQ ID NO. 1594;RNA;Artificial Sequence> aacgagcuguacaugauga
<SEQ ID NO. 1595;RNA;Artificial Sequence> augcgggacugcuggcaug
<SEQ ID NO. 1596;RNA;Artificial Sequence> gcagugcccucacagagac
<SEQ ID NO. 1597;RNA;Artificial Sequence> cccaccuucaagcagcugg
<SEQ ID NO. 1598;RNA;Artificial Sequence> guggaagaccuggaccgca
<SEQ ID NO. 1599;RNA;Artificial Sequence> aucguggccuugaccucca
<SEQ ID NO. 1600;RNA;Artificial Sequence> aaccaggaguaccuggacc
<SEQ ID NO. 1601;RNA;Artificial Sequence> cuguccaugccccuggacc
<SEQ ID NO. 1602;RNA;Artificial Sequence> caguacucccccagcuuuc
<SEQ ID NO. 1603;RNA;Artificial Sequence> cccgacacccggagcucua
<SEQ ID NO. 1604;RNA;Artificial Sequence> acgugcuccucaggggagg
<SEQ ID NO. 1605;RNA;Artificial Sequence> gauuccgucuucucucaug
<SEQ ID NO. 1606;RNA;Artificial Sequence> gagccgcugcccgaggagc
<SEQ ID NO. 1607;RNA;Artificial Sequence> cccugccugccccgacacc
<SEQ ID NO. 1608;RNA;Artificial Sequence> ccagcccagcuugccaaug
<SEQ ID NO. 1609;RNA;Artificial Sequence> ggcggacucaaacgccgcu
<SEQ ID NO. 1610;RNA;Artificial Sequence> ugacugccacccacacgcc
<SEQ ID NO. 1611;RNA;Artificial Sequence> ccuccccagacuccaccgu
<SEQ ID NO. 1612;RNA;Artificial Sequence> ucagcuguaacccucaccc
<SEQ ID NO. 1613;RNA;Artificial Sequence> cacagccccugcugggccc
<SEQ ID NO. 1614;RNA;Artificial Sequence> caccaccuguccgucccug
<SEQ ID NO. 1615;RNA;Artificial Sequence> guccccuuuccugcuggca
<SEQ ID NO. 1616;RNA;Artificial Sequence> aggagccggcugccuacca
<SEQ ID NO. 1617;RNA;Artificial Sequence> aggggccuuccuguguggc
<SEQ ID NO. 1618;RNA;Artificial Sequence> ccugccuucaccccacuca
<SEQ ID NO. 1619;RNA;Artificial Sequence> agcucaccucucccuccac
<SEQ ID NO. 1620;RNA;Artificial Sequence> ccuccucuccaccugcugg
<SEQ ID NO. 1621;RNA;Artificial Sequence> gugagaggugcaaagaggc
<SEQ ID NO. 1622;RNA;Artificial Sequence> cagaucuuugcugccagcc
<SEQ ID NO. 1623;RNA;Artificial Sequence> cacuucauccccucccaga
<SEQ ID NO. 1624;RNA;Artificial Sequence> auguuggaccaacaccccu
<SEQ ID NO. 1625;RNA;Artificial Sequence> ucccugccaccaggcacug
<SEQ ID NO. 1626;RNA;Artificial Sequence> gccuggagggcagggagug
<SEQ ID NO. 1627;RNA;Artificial Sequence> gggagccaaugaacaggca
<SEQ ID NO. 1628;RNA;Artificial Sequence> augcaagugagagcuuccu
<SEQ ID NO. 1629;RNA;Artificial Sequence> ugagcuuucuccugucggu
<SEQ ID NO. 1630;RNA;Artificial Sequence> uuuggucuguuuugccuuc
<SEQ ID NO. 1631;RNA;Artificial Sequence> cacccauaagccccucgca
<SEQ ID NO. 1632;RNA;Artificial Sequence> acucugguggcaggugccu
<SEQ ID NO. 1633;RNA;Artificial Sequence> uuguccucagggcuacagc
<SEQ ID NO. 1634;RNA;Artificial Sequence> caguagggaggucagugcu
<SEQ ID NO. 1635;RNA;Artificial Sequence> uucgugccucgauugaagg
<SEQ ID NO. 1636;RNA;Artificial Sequence> gugaccucugccccagaua
<SEQ ID NO. 1637;RNA;Artificial Sequence> agguggugccaguggcuua
<SEQ ID NO. 1638;RNA;Artificial Sequence> auuaauuccgauacuaguu
<SEQ ID NO. 1639;RNA;Artificial Sequence> uugcuuugcugaccaaaug
<SEQ ID NO. 1640;RNA;Artificial Sequence> gccugguaccagaggaugg
<SEQ ID NO. 1641;RNA;Artificial Sequence> gugaggcgaaggccagguu
<SEQ ID NO. 1642;RNA;Artificial Sequence> ugggggcaguguuguggcc
<SEQ ID NO. 1643;RNA;Artificial Sequence> ccuggggcccagccccaaa
<SEQ ID NO. 1644;RNA;Artificial Sequence> acugggggcucuguauaua
<SEQ ID NO. 1645;RNA;Artificial Sequence> agcuaugaagaaaacacaa
<SEQ ID NO. 1646;RNA;Artificial Sequence> aaguguauaaaucugagua
<SEQ ID NO. 1647;RNA;Artificial Sequence> auauauuuacaugucuuuu
<SEQ ID NO. 1648;RNA;Artificial Sequence> uuaaaagggucguuaccag
<SEQ ID NO. 1649;RNA;Artificial Sequence> gagauuuacccaucgggua
<SEQ ID NO. 1650;RNA;Artificial Sequence> aagaugcuccugguggcug
<SEQ ID NO. 1651;RNA;Artificial Sequence> gggaggcaucaguugcuau
741-3698

CA 02677068 2009-09-01
<SEQ ID NO. 1652;RNA;Artificial Sequence> uauauuaaaaacaaaaaag
<SEQ ID NO. 1653;RNA;Artificial Sequence> gaaaaaaaaggaaaauguu
<SEQ ID NO. 1654;RNA;Artificial Sequence> uuuuaaaaaggucauauau
<SEQ ID NO. 1655;RNA;Artificial Sequence> uuuuuugcuacuuuugcug
<SEQ ID NO. 1656;RNA;Artificial Sequence> guuuuauuuuuuuaaauua
<SEQ ID NO. 1657;RNA;Artificial Sequence> auguucuaaaccuauuuuc
<SEQ ID NO. 1658;RNA;Artificial Sequence> caguuuaggucccucaaua
<SEQ ID NO. 1659;RNA;Artificial Sequence> aaaaauugcugcugcuuca
<SEQ ID NO. 1660;RNA;Artificial Sequence> auuuaucuaugggcuguau
<SEQ ID NO. 1661;RNA;Artificial Sequence> ugaaaagggugggaauguc
<SEQ ID NO. 1662;RNA;Artificial Sequence> ccacuggaaagaagggaca
<SEQ ID NO. 1663;RNA;Artificial Sequence> acccacgggcccuggggcu
<SEQ ID NO. 1664;RNA;Artificial Sequence> uaggucugucccgagggca
<SEQ ID NO. 1665;RNA;Artificial Sequence> accgcaugcucccggcgca
<SEQ ID NO. 1666;RNA;Artificial Sequence> agguuccuuguaaccucuu
<SEQ ID NO. 1667;RNA;Artificial Sequence> ucuuccuagguccugcacc
<SEQ ID NO. 1668;RNA;Artificial Sequence> ccagaccucacgacgcacc
<SEQ ID NO. 1669;RNA;Artificial Sequence> cuccugccucuccgcugcu
<SEQ ID NO. 1670;RNA;Artificial Sequence> uuuuggaaagucagaaaaa
<SEQ ID NO. 1671;RNA;Artificial Sequence> agaagaugucugcuucgag
<SEQ ID NO. 1672;RNA;Artificial Sequence> gggcaggaaccccauccau
<SEQ ID NO. 1673;RNA;Artificial Sequence> ugcaguagaggcgcugggc
<SEQ ID NO. 1674;RNA;Artificial Sequence> cagagagucaaggcccagc
<SEQ ID NO. 1675;RNA;Artificial Sequence> cagccaucgaccauggaug
<SEQ ID NO. 1676;RNA;Artificial Sequence> gguuuccuccaaggaaacc
<SEQ ID NO. 1677;RNA;Artificial Sequence> cggugggguugggcugggg
<SEQ ID NO. 1678;RNA;Artificial Sequence> gagggggcaccuaccuagg
<SEQ ID NO. 1679;RNA;Artificial Sequence> gaauagccacgggguagag
<SEQ ID NO. 1680;RNA;Artificial Sequence> gcuacagugauuaagagga
<SEQ ID NO. 1681;RNA;Artificial Sequence> aaagcaagggcgcgguugc
<SEQ ID NO. 1682;RNA;Artificial Sequence> cucacgccuguaaucccag
<SEQ ID NO. 1683;RNA;Artificial Sequence> gcacuuugggacaccgagg
<SEQ ID NO. 1684;RNA;Artificial Sequence> gugggcagaucacuucagg
<SEQ ID NO. 1685;RNA;Artificial Sequence> gucaggaguuugagaccag
<SEQ ID NO. 1686;RNA;Artificial Sequence> gccuggccaacuuagugaa
<SEQ ID NO. 1687;RNA;Artificial Sequence> aaccccaucucuacuaaaa
<SEQ ID NO. 1688;RNA;Artificial Sequence> aaugcaaaaauuauccagg
<SEQ ID NO. 1689;RNA;Artificial Sequence> gcaugguggcacacgccug
<SEQ ID NO. 1690;RNA;Artificial Sequence> guaaucccagcuccacagg
<SEQ ID NO. 1691;RNA;Artificial Sequence> gaggcugaggcagaauccc
<SEQ ID NO. 1692;RNA;Artificial Sequence> cuugaagcugggaggcgga
<SEQ ID NO. 1693;RNA;Artificial Sequence> agguugcagugagccgaga
<SEQ ID NO. 1694;RNA;Artificial Sequence> auugcgccauugcacucca
<SEQ ID NO. 1695;RNA;Artificial Sequence> agccugggcaacagagaaa
<SEQ ID NO. 1696;RNA;Artificial Sequence> aacaaaaaggaaaacaaau
<SEQ ID NO. 1697;RNA;Artificial Sequence> ugaugaaggucugcagaaa
<SEQ ID NO. 1698;RNA;Artificial Sequence> acugaaacccagacaugug
<SEQ ID NO. 1699;RNA;Artificial Sequence> gucugcccccucuaugugg
<SEQ ID NO. 1700;RNA;Artificial Sequence> ggcaugguuuugccagugc
<SEQ ID NO. 1701;RNA;Artificial Sequence> cuucuaagugcaggagaac
<SEQ ID NO. 1702;RNA;Artificial Sequence> caugucaccugaggcuagu
<SEQ ID NO. 1703;RNA;Artificial Sequence> uuuugcauucaggucccug
<SEQ ID NO. 1704;RNA;Artificial Sequence> ggcuucguuucuuguuggu
<SEQ ID NO. 1705;RNA;Artificial Sequence> uaugccuccccagaucguc
<SEQ ID NO. 1706;RNA;Artificial Sequence> ccuuccuguauccauguga
<SEQ ID NO. 1707;RNA;Artificial Sequence> accagacuguauuuguugg
<SEQ ID NO. 1708;RNA;Artificial Sequence> ggacugucgcagaucuugg
<SEQ ID NO. 1709;RNA;Artificial Sequence> gcuucuuacaguucuuccu
<SEQ ID NO. 1710;RNA;Artificial Sequence> uguccaaacuccauccugu
<SEQ ID NO. 1711;RNA;Artificial Sequence> ucccucaggaacgggggga
<SEQ ID NO. 1712;RNA;Artificial Sequence> aaaauucuccgaauguuuu
<SEQ ID NO. 1713;RNA;Artificial Sequence> uugguuuuuuggcugcuug
<SEQ ID NO. 1714;RNA;Artificial Sequence> ggaauuuacuucugccacc
<SEQ ID NO. 1715;RNA;Artificial Sequence> cugcuggucaucacugucc
<SEQ ID NO. 1716;RNA;Artificial Sequence> cucacuaaguggauucugg
<SEQ ID NO. 1717;RNA;Artificial Sequence> gcucccccguaccucaugg
<SEQ ID NO. 1718;RNA;Artificial Sequence> gcucaaacuaccacuccuc
<SEQ ID NO. 1719;RNA;Artificial Sequence> cagucgcuauauuaaagcu
<SEQ ID NO. 1720;RNA;Artificial Sequence> uuauauuuugcuggauuac
<SEQ ID NO. 1721;RNA;Artificial Sequence> cugcuaaauacaaaagaaa
<SEQ ID NO. 1722;RNA;Artificial Sequence> aguucaauauguuuucauu
<SEQ ID NO. 1723;RNA;Artificial Sequence> uucuguagggaaaauggga
<SEQ ID NO. 1724;RNA;Artificial Sequence> auugcugcuuuaaauuucu
741-3699

CA 02677068 2009-09-01
<SEQ ID NO. 1725;RNA;Artificial Sequence> ugagcuagggauuuuuugg
<SEQ ID NO. 1726;RNA;Artificial Sequence> gcagcugcaguguuggcga
<SEQ ID NO. I727;RNA;Artificial Sequence> acuauuguaaaauucucuu
<SEQ ID NO. 1728;RNA;Artificial Sequence> uuguuucucucuguaaaua
<SEQ ID NO. 1729;RNA;Artificial Sequence> agcaccugcuaacauuaca
<SEQ ID NO. 1730;RNA;Artificial Sequence> aauuuguauuuauguuuaa
<SEQ ID NO. 1731;RNA;Artificial Sequence> aagaaggcaucauuuggug
<SEQ ID NO. 1732;RNA;Artificial Sequence> gaacagaacuaggaaauga
<SEQ ID NO. 1733;RNA;Artificial Sequence> aauuuuuagcucuuaaaag
<SEQ ID NO. 1734;RNA;Artificial Sequence> gcauuugcuuugagaccgc
<SEQ ID NO. 1735;RNA;Artificial Sequence> cacaggagugucuuuccuu
<SEQ ID NO. 1736;RNA;Artificial Sequence> uguaaaacagugaugauaa
<SEQ ID NO. 1737;RNA;Artificial Sequence> auuucugccuuggcccuac
<SEQ ID NO. 1738;RNA;Artificial Sequence> ccuugaagcaauguugugu
<SEQ ID NO. 1739;RNA;Artificial Sequence> ugaagggaugaagaaucua
<SEQ ID NO. 1740;RNA;Artificial Sequence> aaaagucuucauaaguccu
<SEQ ID NO. 1741;RNA;Artificial Sequence> uugggagaggugcuagaaa
<SEQ ID NO. 1742;RNA;Artificial Sequence> aaauauaaggcacuaucau
<SEQ ID NO. 1743;RNA;Artificial Sequence> uaauuacagugauguccuu
<SEQ ID NO. 1744;RNA;Artificial Sequence> ugcuguuacuacucaaauc
<SEQ ID NO. 1745;RNA;Artificial Sequence> cacccacaaauuuccccaa
<SEQ ID NO. 1746;RNA;Artificial Sequence> aagacugcgcuagcuguca
<SEQ ID NO. 1747;RNA;Artificial Sequence> aaauaaaagacagugaaau
<SEQ ID NO. 1748;RNA;Artificial Sequence> aacaccaaaccaaaccgua
<SEQ ID NO. 1749;RNA;Artificial Sequence> augcccguagcuccauauu
<SEQ ID NO. 1750;RNA;Artificial Sequence> uggacauccccagaaaaga
<SEQ ID NO. 1751;RNA;Artificial Sequence> auggaaaagaaauugcaug
<SEQ ID NO. 1752;RNA;Artificial Sequence> gcagugccggcugccaaga
<SEQ ID NO. 1753;RNA;Artificial Sequence> acagugaaguucaaaugcc
<SEQ ID NO. 1754;RNA;Artificial Sequence> ccuuccagugggaccccaa
<SEQ ID NO. 1755;RNA;Artificial Sequence> aaccccacacugcgcuggu
<SEQ ID NO. 1756;RNA;Artificial Sequence> uugaaaaauggcaaagaau
<SEQ ID NO. 1757;RNA;Artificial Sequence> uucaaaccugaccacagaa
<SEQ ID NO. 1758;RNA;Artificial Sequence> auuggaggcuacaaggucc
<SEQ ID NO. 1759;RNA;Artificial Sequence> cguuaugccaccuggagca
<SEQ ID NO. 1760;RNA;Artificial Sequence> aucauaauggacucugugg
<SEQ ID NO. 1761;RNA;Artificial Sequence> gugcccucugacaagggca
<SEQ ID NO. 1762;RNA;Artificial Sequence> aacuacaccugcauugugg
<SEQ ID NO. 1763;RNA;Artificial Sequence> gagaaugaguacggcagca
<SEQ ID NO. 1764;RNA;Artificial Sequence> aucaaccacacauaccagc
<SEQ ID NO. 1765;RNA;Artificial Sequence> cuggaugucguggagcggu
<SEQ ID NO. 1766;RNA;Artificial Sequence> uccccucaccggcccaucc
<SEQ ID NO. 1767;RNA;Artificial Sequence> cugcaagcaggguugcccg
<SEQ ID NO. 1768;RNA;Artificial Sequence> gccaacaaaacaguggccc
<SEQ ID NO. 1769;RNA;Artificial Sequence> cuggguagcaacguggagu
<SEQ ID NO. 1770;RNA;Artificial Sequence> uucauguguaagguguaca
<SEQ ID NO. 1771;RNA;Artificial Sequence> agugacccgcagccgcaca
<SEQ ID NO. 1772;RNA;Artificial Sequence> auccaguggcuaaagcaca
<SEQ ID NO. 1773;RNA;Artificial Sequence> aucgaggugaaugggagca
<SEQ ID NO. I774;RNA;Artificial Sequence> aagauuggcccagacaacc
<SEQ ID NO. 1775;RNA;Artificial Sequence> cugccuuauguccagaucu
<SEQ ID NO. 1776;RNA;Artificial Sequence> uugaagacugcuggaguua
<SEQ ID NO. 1777;RNA;Artificial Sequence> aauaccaccgacaaagaga
<SEQ ID NO. 1778;RNA;Artificial Sequence> auggaggugcuucacuuaa
<SEQ ID NO. 1779;RNA;Artificial Sequence> agaaaugucuccuuugagg
<SEQ ID NO. 1780;RNA;Artificial Sequence> gacgcaggggaguauacgu
<SEQ ID NO. 1781;RNA;Artificial Sequence> ugcuuggcggguaacucua
<SEQ ID NO. 1782;RNA;Artificial Sequence> aucggacucucccaucacu
<SEQ ID NO. 1783;RNA;Artificial Sequence> ucugcaugguugaccguuc
<SEQ ID NO. 1784;RNA;Artificial Sequence> cuggaagcccuggaagaga
<SEQ ID NO. I785;RNA;Artificial Sequence> aggccggcagugaugaccu
<SEQ ID NO. 1786;RNA;Artificial Sequence> ucgccecuguaccuggaga
<SEQ ID NO. 1787;RNA;Artificial Sequence> aucaucaucuauugcacag
<SEQ ID NO. 1788;RNA;Artificial Sequence> ggggccuuccucaucuccu
<SEQ ID NO. 1789;RNA;Artificial Sequence> ugcaugguggggucgguca
<SEQ ID NO. 1790;RNA;Artificial Sequence> aucgucuacaagaugaaga
<SEQ ID NO. 1791;RNA;Artificial Sequence> agugguaccaagaagagug
<SEQ ID NO. 1792;RNA;Artificial Sequence> gacuuccacagccagaugg
<SEQ ID NO. 1793;RNA;Artificial Sequence> gcugugcacaagcuggcca
<SEQ ID NO. 1794;RNA;Artificial Sequence> aagagcaucccucugcgca
<SEQ ID NO. 1795;RNA;Artificial Sequence> agacagguaacagugucug
<SEQ ID NO. 1796;RNA;Artificial Sequence> gcugacuccagugcaucca
<SEQ ID NO. 1797;RNA;Artificial Sequence> augaacucugggguucuuc
741-3700

CA 02677068 2009-09-01
<SEQ ID NO. 1798;RNA;Artificial Sequence> cugguucggccaucacggc
<SEQ ID NO. 1799;RNA;Artificial Sequence> cucuccuccagugggacuc
<SEQ ID NO. 1800;RNA;Artificial Sequence> cccaugcuagcaggggucu
<SEQ ID NO. 1801;RNA;Artificial Sequence> ucugaguaugagcuucccg
<SEQ ID NO. 1802;RNA;Artificial Sequence> gaagacccucgcugggagc
<SEQ ID NO. 1803;RNA;Artificial Sequence> cugccucgggacagacugg
<SEQ ID NO. 1804;RNA;Artificial Sequence> gucuuaggcaaaccccugg
<SEQ ID NO. 1805;RNA;Artificial Sequence> ggagagggcugcuuugggc
<SEQ ID NO. 1806;RNA;Artificial Sequence> caggugguguuggcagagg
<SEQ ID NO. 1807;RNA;Artificial Sequence> gcuaucgggcuggacaagg
<SEQ ID NO. 1808;RNA;Artificial Sequence> gacaaacccaaccguguga
<SEQ ID NO. 1809;RNA;Artificial Sequence> accaaaguggcugugaaga
<SEQ ID NO. 1810;RNA;Artificial Sequence> auguugaagucggacgcaa
<SEQ ID NO. 1811;RNA;Artificial Sequence> acagagaaagacuugucag
<SEQ ID NO. 1812;RNA;Artificial Sequence> gaccugaucucagaaaugg
<SEQ ID NO. 1813;RNA;Artificial Sequence> gagaugaugaagaugaucg
<SEQ ID NO. 1814;RNA;Artificial Sequence> gggaagcauaagaauauca
<SEQ ID NO. 1815;RNA;Artificial Sequence> aucaaccugcugggggccu
<SEQ ID NO. 1816;RNA;Artificial Sequence> ugcacgcaggauggucccu
<SEQ ID NO. 1817;RNA;Artificial Sequence> uuguaugucaucguggagu
<SEQ ID NO. 1818;RNA;Artificial Sequence> uaugccuccaagggcaacc
<SEQ ID NO. 1819;RNA;Artificial Sequence> cugcgggaguaccugcagg
<SEQ ID NO. I820;RNA;Artificial Sequence> gcccggaggcccccagggc
<SEQ ID NO. 1821;RNA;Artificial Sequence> cuggaauacugcuacaacc
<SEQ ID NO. 1822;RNA;Artificial Sequence> cccagccacaacccagagg
<SEQ ID NO. 1823;RNA;Artificial Sequence> gagcagcucuccuccaagg
<SEQ ID NO. I824;RNA;Artificial Sequence> gaccugguguccugcgccu
<SEQ ID NO. 1825;RNA;Artificial Sequence> uaccagguggcccgaggca
<SEQ ID NO. 1826;RNA;Artificial Sequence> auggaguaucuggccucca
<SEQ ID NO. 1827;RNA;Artificial Sequence> aagaagugcauacaccgag
<SEQ ID NO. 1828;RNA;Artificial Sequence> gaccuggcagccaggaaug
<SEQ ID NO. 1829;RNA;Artificial Sequence> guccuggugacagaggaca
<SEQ ID NO. 1830;RNA;Artificial Sequence> aaugugaugaagauagcag
<SEQ ID NO. 1831;RNA;Artificial Sequence> gacuuuggccucgcacggg
<SEQ ID NO. 1832;RNA;Artificial Sequence> gacauucaccacaucgacu
<SEQ ID NO. 1833;RNA;Artificial Sequence> uacuauaaaaagacaacca
<SEQ ID NO. 1834;RNA;Artificial Sequence> aacggccgacugccuguga
<SEQ ID NO. 1835;RNA;Artificial Sequence> aaguggauggcacccgagg
<SEQ ID NO. 1836;RNA;Artificial Sequence> gcauuauuugaccggaucu
<SEQ ID NO. 1837;RNA;Artificial Sequence> uacacccaccagagugaug
<SEQ ID NO. 1838;RNA;Artificial Sequence> guguggucuuucggggugc
<SEQ ID NO. 1839;RNA;Artificial Sequence> cuccugugggagaucuuca
<SEQ ID NO. 1840;RNA;Artificial Sequence> acucugggcggcuccccau
<SEQ ID NO. 1841;RNA;Artificial Sequence> uaccccggugugccugugg
<SEQ ID NO. 1842;RNA;Artificial Sequence> gaggaacuuuucaagcugc
<SEQ ID NO. 1843;RNA;Artificial Sequence> cugaaggagggucaccgca
<SEQ ID NO. 1844;RNA;Artificial Sequence> auggacaagcccaguaacu
<SEQ ID NO. 1845;RNA;Artificial Sequence> ugcaccaacgagcuguaca
<SEQ ID NO. 1846;RNA;Artificial Sequence> augaugaugcgggacugcu
<SEQ ID NO. 1847;RNA;Artificial Sequence> uggcaugcagugcccucac
<SEQ ID NO. 1848;RNA;Artificial Sequence> cagagacccaccuucaagc
<SEQ ID NO. 1849;RNA;Artificial Sequence> cagcugguggaagaccugg
<SEQ ID NO. 1850;RNA;Artificial Sequence> gaccgcaucguggccuuga
<SEQ ID NO. 1851;RNA;Artificial Sequence> accuccaaccaggaguacc
<SEQ ID NO. 1852;RNA;Artificial Sequence> cuggaccuguccaugcccc
<SEQ ID NO. 1853;RNA;Artificial Sequence> cuggaccaguacuccccca
<SEQ ID NO. 1854;RNA;Artiicial Sequence> agcuuucccgacacccgga
<SEQ ID NO. 1855;RNA;Artificial Sequence> agcucuacgugcuccucag
<SEQ ID NO. 1856;RNA;Artificial Sequence> ggggaggauuccgucuucu
<SEQ ID NO. 1857;RNA;Artificial Sequence> ucucaugagccgcugcccg
<SEQ ID NO. 1858;RNA;Artificial Sequence> gaggagcccugccugcccc
<SEQ ID NO. 1859;RNA;Artificial Sequence> cgacacccagcccagcuug
<SEQ ID NO. 1860;RNA;Artificial Sequence> gccaauggcggacucaaac
<SEQ ID NO. 1861;RNA;Artificial Sequence> cgccgcugacugccaccca
<SEQ ID NO. 1862;RNA;Artificial Sequence> acacgcccuccccagacuc
<SEQ ID NO. 1863;RNA;Artificial Sequence> ccaccgucagcuguaaccc
<SEQ ID NO. 1864;RNA;Artificial Sequence> cucacccacagccccugcu
<SEQ ID NO. 1865;RNA;Artificial Sequence> ugggcccaccaccuguccg
<SEQ ID NO. 1866;RNA;Artificial Sequence> gucccuguccccuuuccug
<SEQ ID NO. I867;RNA;Artificial Sequence> gcuggcaggagccggcugc
<SEQ ID NO. I868;RNA;Artificial Sequence> ccuaccaggggccuuccug
<SEQ ID NO. I869;RNA;Artificial Sequence> guguggccugccuucaccc
<SEQ ID NO. 1870;RNA;Artificial Sequence> ccacucagcucaccucucc
741-3701

CA 02677068 2009-09-01
<SEQ ID NO. 1871;RNA;Artificial Sequence> ccuccaccuccucuccacc
<SEQ ID NO. 1872;RNA;Artificial Sequence> cugcuggugagaggugcaa
<SEQ ID NO. 1873;RNA;Artificial Sequence> aagaggcagaucuuugcug
<SEQ ID NO. 1874;RNA;Artificial Sequence> gccagccacuucauccccu
<SEQ ID NO. 1875;RNA;Artificial Sequence> ucccagauguuggaccaac
<SEQ ID NO. 1876;RNA;Artificial Sequence> caccccucccugccaccag
<SEQ ID NO. 1877;RNA;Artificial Sequence> ggcacugccuggagggcag
<SEQ ID NO. 1878;RNA;Artificial Sequence> gggagugggagccaaugaa
<SEQ ID NO. 1879;RNA;Artificial Sequence> acaggcaugcaagugagag
<SEQ ID NO. 1880;RNA;Artificial Sequence> gcuuccugagcuuucuccu
<SEQ ID NO. 1881;RNA;Artificial Sequence> ugucgguuuggucuguuuu
<SEQ ID NO. 1882;RNA;Artificial Sequence> ugccuucacccauaagccc
<SEQ ID NO. 1883;RNA;Artificial Sequence> ccucgcacucugguggcag
<SEQ ID NO. 1884;RNA;Artificial Sequence> ggugccuuguccucagggc
<SEQ ID NO. 1885;RNA;Artificial Sequence> cuacagcaguagggagguc
<SEQ ID NO. 1886;RNA;Artificial Sequence> cagugcuucgugccucgau
<SEQ ID NO. 1887;RNA;Artificial Sequence> uugaaggugaccucugccc
<SEQ ID NO. 1888;RNA;Artificial Sequence> ccagauagguggugccagu
<SEQ ID NO. 1889;RNA;Artificial Sequence> uggcuuauuaauuccgaua
<SEQ ID NO. 1890;RNA;Artificial Sequence> acuaguuugcuuugcugac
<SEQ ID NO. 1891;RNA;Artificial Sequence> ccaaaugccugguaccaga
<SEQ ID NO. 1892;RNA;Artificial Sequence> aggauggugaggcgaaggc
<SEQ ID NO. 1893;RNA;Artificial Sequence> ccagguugggggcaguguu
<SEQ ID NO. 1894;RNA;Artificial Sequence> uguggcccuggggcccagc
<SEQ ID NO. 1895;RNA;Artificial Sequence> ccccaaacugggggcucug
<SEQ ID NO. 1896;RNA;Artificial Sequence> guauauagcuaugaagaaa
<SEQ ID NO. 1897;RNA;Artificial Sequence> aacacaaaguguauaaauc
<SEQ ID NO. 1898;RNA;Artificial Sequence> cugaguauauauuuacaug
<SEQ ID NO. 1899;RNA;Artificial Sequence> gucuuuuuaaaagggucgu
<SEQ ID NO. 1900;RNA;Artificial Sequence> uuaccagagauuuacccau
<SEQ ID NO. 1901;RNA;Artificial Sequence> ucggguaagaugcuccugg
<SEQ ID NO. 1902;RNA;Artificial Sequence> guggcugggaggcaucagu
<SEQ ID NO. 1903;RNA;Artificial Sequence> uugcuauauauuaaaaaca
<SEQ ID NO. 1904;RNA;Artificial Sequence> aaaaaagaaaaaaaaggaa
<SEQ ID NO. 1905;RNA;Artificial Sequence> aaauguuuuuaaaaagguc
<SEQ ID NO. 1906;RNA;Artificial Sequence> cauauauuuuuugcuacuu
<SEQ ID NO. 1907;RNA;Artificial Sequence> uuugcuguuuuauuuuuuu
<SEQ ID NO. 1908;RNA;Artificial Sequence> uaaauuauguucuaaaccu
<SEQ ID NO. 1909;RNA;Artificial Sequence> uauuuucaguuuagguccc
<SEQ ID NO. 1910;RNA;Artificial Sequence> cucaauaaaaauugcugcu
<SEQ ID NO. 1911;RNA;Artificial Sequence> ugcuucauuuaucuauggg
<SEQ ID NO. 1912;RNA;Artificial Sequence> gcuguaugaaaaggguggg
<SEQ ID NO. 1913;RNA;Artificial Sequence> gaauguccacuggaaagaa
<SEQ ID NO. 1914;RNA;Artificial Sequence> agggacacccacgggcccu
<SEQ ID NO. 1915;RNA;Artificial Sequence> uggggcuaggucugucccg
<SEQ ID NO. 1916;RNA;Artificial Sequence> gagggcaccgcaugcuccc
<SEQ ID NO. 1917;RNA;Artificial Sequence> cggcgcagguuccuuguaa
<SEQ ID NO. 1918;RNA;Artificial Sequence> accucuucuuccuaggucc
<SEQ ID NO. 1919;RNA;Artificial Sequence> cugcacccagaccucacga
<SEQ ID NO. 1920;RNA;Artificial Sequence> acgcaccuccugccucucc
<SEQ ID NO. 1921;RNA;Artificial Sequence> cgcugcuuuuggaaaguca
<SEQ ID NO. 1922;RNA;Artificial Sequence> agaaaaagaagaugucugc
<SEQ ID NO. 1923;RNA;Artificial Sequence> cuucgagggcaggaacccc
<SEQ ID NO. I924;RNA;Artificial Sequence> cauccaugcaguagaggcg
<SEQ ID NO. 1925;RNA;Artificial Sequence> gcugggcagagagucaagg
<SEQ ID NO. 1926;RNA;Artificial Sequence> gcccagcagccaucgacca
<SEQ ID NO. 1927;RNA;Artificial Sequence> auggaugguuuccuccaag
<SEQ ID NO. 1928;RNA;Artificial Sequence> ggaaaccggugggguuggg
<SEQ ID NO. 1929;RNA;Artificial Sequence> gcuggggagggggcaccua
<SEQ ID NO. 1930;RNA;Artificial Sequence> accuaggaauagccacggg
<SEQ ID NO. 1931;RNA;Artificial Sequence> gguagagcuacagugauua
<SEQ ID NO. 1932;RNA;Artificial Sequence> aagaggaaagcaagggcgc
<SEQ ID NO. 1933;RNA;Artificial Sequence> cgguugcucacgccuguaa
<SEQ ID NO. 1934;RNA;Artificial Sequence> aucccagcacuuugggaca
<SEQ ID NO. 1935;RNA;Artificial Sequence> accgaggugggcagaucac
<SEQ ID NO. 1936;RNA;Artificial Sequence> cuucaggucaggaguuuga
<SEQ ID NO. 1937;RNA;Artificial Sequence> agaccagccuggccaacuu
<SEQ ID NO. 1938;RNA;Artificial Sequence> uagugaaaccccaucucua
<SEQ ID NO. 1939;RNA;Artificial Sequence> acuaaaaaugcaaaaauua
<SEQ ID NO. 1940;RNA;Artificial Sequence> auccaggcaugguggcaca
<SEQ ID NO. 1941;RNA;Artificial Sequence> acgccuguaaucccagcuc
<SEQ ID NO. 1942;RNA;Artificial Sequence> ccacaggaggcugaggcag
<SEQ ID NO. 1943;RNA;Artificial Sequence> gaaucccuugaagcuggga
741-3702

CA 02677068 2009-09-01
<SEQ ID NO. 1944;RNA;Artificial Sequence> aggcggagguugcagugag
<SEQ ID NO. 1945;RNA;Artificial Sequence> gccgagauugcgccauugc
<SEQ ID NO. 1946;RNA;Artificial Sequence> cacuccagccugggcaaca
<SEQ ID NO. 1947;RNA;Artificial Sequence> agagaaaacaaaaaggaaa
<SEQ ID NO. 1948;RNA;Artificial Sequence> aacaaaugaugaaggucug
<SEQ ID NO. 1949;RNA;Artificial Sequence> gcagaaacugaaacccaga
<SEQ ID NO. 1950;RNA;Artificial Sequence> acaugugucugcccccucu
<SEQ ID NO. 1951;RNA;Artificial Sequences uaugugggcaugguuuugc
<SEQ ID NO. 1952;RNA;Artificial Sequence> ccagugcuucuaagugcag
<SEQ ID NO. 1953;RNA;Artificial Sequence> ggagaacaugucaccugag
<SEQ ID NO. 1954;RNA;Artificial Sequence> ggcuaguuuugcauucagg
<SEQ ID NO. 1955;RNA;Artificial Sequence> gucccuggcuucguuucuu
<SEQ ID NO. 1956;RNA;Artificial Sequence> uguugguaugccuccccag
<SEQ ID NO. 1957;RNA;Artificial Sequence> gaucguccuuccuguaucc
<SEQ ID NO. 1958;RNA;Artificial Sequence> caugugaccagacuguauu
<SEQ ID NO. 1959;RNA;Artificial Sequence> uuguugggacugucgcaga
<SEQ ID NO. 1960;RNA;Artificial Sequence> aucuuggcuucuuacaguu
<SEQ ID NO. 1961;RNA;Artificial Sequence> ucuuccuguccaaacucca
<SEQ ID NO. 1962;RNA;Artificial Sequence> auccugucccucaggaacg
<SEQ ID NO. 1963;RNA;Artificial Sequence> ggggggaaaauucuccgaa
<SEQ ID NO. 1964;RNA;Artificial Sequence> auguuuuugguuuuuuggc
<SEQ ID NO. 1965;RNA;Artificial Sequence> cugcuuggaauuuacuucu
<SEQ ID NO. 1966;RNA;Artificial Sequence> ugccaccugcuggucauca
<SEQ ID NO. 1967;RNA;Artificial Sequence> acuguccucacuaagugga
<SEQ ID NO. 1968;RNA;Artificial Sequence> auucuggcucccccguacc
<SEQ ID NO. 1969;RNA;Artificial Sequence> cucauggcucaaacuacca
<SEQ ID NO. 1970;RNA;Artificial Sequence> acuccucagucgcuauauu
<SEQ ID NO. 1971;RNA;Artificial Sequence> uaaagcuuauauuuugcug
<SEQ ID NO. 1972;RNA;Artificial Sequence> ggauuacugcuaaauacaa
<SEQ ID NO. 1973;RNA;Artificial Sequence> aaagaaaguucaauauguu
<SEQ ID NO. 1974;RNA;Artificial Sequence> uuucauuucuguagggaaa
<SEQ ID NO. 1975;RNA;Artificial Sequence> aaugggauugcugcuuuaa
<SEQ ID NO. 1976;RNA;Artificial Sequence> aauuucugagcuagggauu
<SEQ ID NO. 1977;RNA;Artificial Sequence> uuuuuggcagcugcagugu
<SEQ ID NO. 1978;RNA;Artificial Sequence> uuggcgacuauuguaaaau
<SEQ ID NO. I979;RNA;Artificial Sequence> uucucuuuguuucucucug
<SEQ ID NO. 1980;RNA;Artificial Sequence> guaaauagcaccugcuaac
<SEQ ID NO. 1981;RNA;Artificial Sequence> cauuacaauuuguauuuau
<SEQ ID NO. 1982;RNA;Artificial Sequence> uguuuaaagaaggcaucau
<SEQ ID NO. 1983;RNA;Artificial Sequence> uuuggugaacagaacuagg
<SEQ ID NO. 1984;RNA;Artificial Sequence> gaaaugaauuuuuagcucu
<SEQ ID NO. 1985;RNA;Artificial Sequence> uuaaaagcauuugcuuuga
<SEQ ID NO. 1986;RNA;Artificial Sequence> agaccgcacaggagugucu
<SEQ ID NO. 1987;RNA;Artificial Sequence> uuuccuuguaaaacaguga
<SEQ ID NO. 1988;RNA;Artificial Sequence> augauaauuucugccuugg
<SEQ ID NO. 1989;RNA;Artificial Sequence> gcccuaccuugaagcaaug
<SEQ ID NO. 1990;RNA;Artificial Sequence> guugugugaagggaugaag
<SEQ ID NO. 1991;RNA;Artificial Sequence> gaaucuaaaagucuucaua
<SEQ ID NO. 1992;RNA;Artificial Sequence> aaguccuugggagaggugc
<SEQ ID NO. 1993;RNA;Artificial Sequence> cuagaaaaauauaaggcac
<SEQ ID NO. 1994;RNA;Artificial Sequence> cuaucauaauuacagugau
<SEQ ID NO. 1995;RNA;Artificial Sequence> uguccuugcuguuacuacu
<SEQ ID NO. 1996;RNA;Artificial Sequence> ucaaaucacccacaaauuu
<SEQ ID NO. 1997;RNA;Artificial Sequence> uccccaaagacugcgcuag
<SEQ ID NO. 1998;RNA;Artificial Sequence> gcugucaaauaaaagacag
<SEQ ID NO. 1999;RNA;Artificial Sequence> gugaaauugaccugaaaaa
<SEQ ID NO.2000;RNA;Artificial Sequence> gaggaacuuuucaagcagc
<SEQ ID NO. 2001;RNA;Artificial Sequence> cguaugcccguagcuccau
<SEQ ID NO. 2002;RNA;Artificial Sequence> uauuggacauccccagaaa
<SEQ ID NO. 2003;RNA;Artificial Sequence> aagauggaaaagaaauugc
<SEQ ID NO.2004;RNA;Artificial Sequence> caugcagugccggcugcca
<SEQ ID NO. 2005;RNA;Artificial Sequence> aagacagugaaguucaaau
<SEQ ID NO. 2006;RNA;Artificial Sequence> ugcccuuccagugggaccc
<SEQ ID NO.2007;RNA;Artificial Sequence> ccaaaccccacacugcgcu
<SEQ ID NO. 2008;RNA;Artificial Sequence> ugguugaaaaauggcaaag
<SEQ ID NO. 2009;RNA;Artificial Sequence> gaauucaaaccugaccaca
<SEQ ID NO. 2010;RNA;Artificial Sequence> agaauuggaggcuacaagg
<SEQ ID NO. 201 1;RNA;Artificial Sequence> guccguuaugccaccugga
<SEQ ID NO. 2012;RNA;Artificial Sequence> agcaucauaauggacucug
<SEQ ID NO. 2013;RNA;Artificial Sequence> guggugcccucugacaagg
<SEQ ID NO.2014;RNA;Artificial Sequence> ggcaacuacaccugcauug
<SEQ ID NO. 2015;RNA;Artificial Sequence> guggagaaugaguacggca
<SEQ ID NO. 2016;RNA;Artificial Sequence> agcaucaaccacacauacc
741-3703

CA 02677068 2009-09-01
<SEQ ID NO. 2017;RNA;Artificial Sequence> cagcuggaugucguggagc
<SEQ ID NO. 2018;RNA;Artificial Sequence> cgguccccucaccggccca
<SEQ ID NO. 2019;RNA;Artificial Sequence> auccugcaagcaggguugc
<SEQ ID NO. 2020;RNA;Artificial Sequence> cccgccaacaaaacagugg
<SEQ ID NO.2021;RNA;Artificial Sequence> gcccuggguagcaacgugg
<SEQ ID NO. 2022;RNA;Artificial Sequence> gaguucauguguaaggugu
<SEQ ID NO. 2023;RNA;Artificial Sequence> uacagugacccgcagccgc
<SEQ ID NO. 2024;RNA;Artificial Sequence> cacauccaguggcuaaagc
<SEQ ID NO. 2025;RNA;Artificial Sequence> cacaucgaggugaauggga
<SEQ ID NO. 2026;RNA;Artificial Sequence> agcaagauuggcccagaca
<SEQ ID NO. 2027;RNA;Artificial Sequence> aaccugccuuauguccaga
<SEQ ID NO. 2028;RNA;Artificial Sequence> aucuugaagacugcuggag
<SEQ ID NO. 2029;RNA; Artificial Sequence> guuaauaccaccgacaaag
<SEQ ID NO. 2030;RNA;Artificial Sequence> gagauggaggugcuucacu
<SEQ ID NO. 2031;RNA;Artificial Sequence> uuaagaaaugucuccuuug
<SEQ ID NO. 2032;RNA;Artificial Sequence> gaggacgcaggggaguaua
<SEQ ID NO. 2033;RNA;Artificial Sequence> acgugcuuggcggguaacu
<SEQ ID NO. 2034;RNA;Artificial Sequence> ucuaucggacucucccauc
<SEQ ID NO. 2035;RNA;Artificial Sequence> cacucugcaugguugaccg
<SEQ ID NO. 2036;RNA;Artificial Sequence> guucuggaagcccuggaag
<SEQ ID NO. 2037;RNA;Artificial Sequence> gagaggccggcagugauga
<SEQ ID NO. 2038;RNA;Artificial Sequence> accucgccccuguaccugg
<SEQ ID NO. 2039;RNA;Artificial Sequence> gagaucaucaucuauugca
<SEQ ID NO. 2040;RNA;Artificial Sequence> acaggggccuuccucaucu
<SEQ ID NO. 2041;RNA;Artificial Sequence> uccugcaugguggggucgg
<SEQ ID NO. 2042;RNA;Artificial Sequence> gucaucgucuacaagauga
<SEQ ID NO. 2043;RNA;Artificial Sequence> aagagugguaccaagaaga
<SEQ ID NO. 2044;RNA;Artificial Sequence> agugacuuccacagccaga
<SEQ ID NO. 2045;RNA;Artificial Sequence> auggcugugcacaagcugg
<SEQ ID NO. 2046;RNA;Artificial Sequence> gccaagagcaucccucugc
<SEQ ID NO. 2047;RNA; Artificial Sequence> cgcagacagguaacagugu
<SEQ ID NO. 2048;RNA;Artificial Sequence> ucugcugacuccagugcau
<SEQ ID NO. 2049;RNA;Artificial Sequence> uccaugaacucugggguuc
<SEQ ID NO. 2050;RNA;Artificial Sequence> cuucugguucggccaucac
<SEQ ID NO. 2051;RNA;Artificial Sequence> cggcucuccuccaguggga
<SEQ ID NO. 2052;RNA;Artificial Sequence> acucccaugcuagcagggg
<SEQ ID NO. 205 3;RNA; Artificial Sequence> gucucugaguaugagcuuc
<SEQ ID NO. 2054;RNA;Artificial Sequence> cccgaagacccucgcuggg
<SEQ ID NO. 2055;RNA;Artificial Sequence> gagcugccucgggacagac
<SEQ ID NO. 2056;RNA;Artificial Sequence> cuggucuuaggcaaacccc
<SEQ ID NO.2057;RNA;Artificial Sequence> cugggagagggcugcuuug
<SEQ ID NO. 2058;RNA;Artificial Sequence> gggcaggugguguuggcag
<SEQ ID NO. 2059;RNA;Artificial Sequence> gaggcuaucgggcuggaca
<SEQ ID NO. 2060;RNA; Artificial Sequence> aaggacaaacccaaccgug
<SEQ ID NO. 2061;RNA;Artificial Sequence> gugaccaaaguggcuguga
<SEQ ID NO. 2062;RNA;Artificial Sequence> aagauguugaagucggacg
<SEQ ID NO. 2063;RNA;Artificial Sequence> gcaacagagaaagacuugu
<SEQ ID NO.2064;RNA;Artificial Sequence> ucagaccugaucucagaaa
<SEQ ID NO. 2065;RNA;Artificial Sequence> auggagaugaugaagauga
<SEQ ID NO. 2066;RNA; Artificial Sequence> aucgggaagcauaagaaua
<SEQ ID NO. 2067;RNA;Artificial Sequence> aucaucaaccugcuggggg
<SEQ ID NO. 2068;RNA;Artificial Sequence> gccugcacgcaggaugguc
<SEQ ID NO. 2069;RNA;Artificial Sequence> cccuuguaugucaucgugg
<SEQ ID NO. 2070;RNA;Artificial Sequence> gaguaugccuccaagggca
<SEQ ID NO. 2071;RNA;Artificial Sequence> aaccugcgggaguaccugc
<SEQ ID NO. 2072;RNA;Artificial Sequence> caggcccggaggcccccag
<SEQ ID NO. 2073;RNA;Artificial Sequence> gggcuggaauacugcuaca
<SEQ ID NO. 2074;RNA;Artificial Sequence> aaccccagccacaacccag
<SEQ ID NO. 2075;RNA;Artificial Sequence> gaggagcagcucuccucca
<SEQ ID NO. 2076;RNA;Artificial Sequence> aaggaccugguguccugcg
<SEQ ID NO. 2077;RNA;Artificial Sequence> gccuaccagguggcccgag
<SEQ ID NO. 2078;RNA;Artificial Sequence> ggcauggaguaucuggccu
<SEQ ID NO. 2079;RNA;Artificial Sequence> uccaagaagugcauacacc
<SEQ ID NO. 2080;RNA;Artificial Sequence> cgagaccuggcagccagga
<SEQ ID NO. 2081;RNA;Artificial Sequence> aauguccuggugacagagg
<SEQ ID NO. 2082;RNA;Artificial Sequence> gacaaugugaugaagauag
<SEQ ID NO. 2083;RNA;Artificial Sequence> gcagacuuuggccucgcac
<SEQ ID NO. 2084;RNA;Artificial Sequence> cgggacauucaccacaucg
<SEQ ID NO. 2085;RNA;Artificial Sequence> gacuacuauaaaaagacaa
<SEQ ID NO. 2086;RNA;Artificial Sequence> accaacggccgacugccug
<SEQ ID NO. 2087;RNA;Artificial Sequence> gugaaguggauggcacccg
<SEQ ID NO. 2088;RNA;Artificial Sequence> gaggcauuauuugaccgga
<SEQ ID NO. 2089;RNA;Artificial Sequence> aucuacacccaccagagug
741-3704

CA 02677068 2009-09-01
<SEQ ID NO. 2090;RNA;Artificial Sequence> gauguguggucuuucgggg
<SEQ ID NO. 2091;RNA;Artificial Sequence> gugcuccugugggagaucu
<SEQ ID NO. 2092;RNA;Artificial Sequence> uucacucugggcggcuccc
<SEQ ID NO. 2093;RNA;Artificial Sequence> ccauaccccggugugccug
<SEQ ID NO. 2094;RNA;Artificial Sequence> guggaggaacuuuucaagc
<SEQ ID NO. 2095;RNA;Artificial Sequence> cugcugaaggagggucacc
<SEQ ID NO. 2096;RNA;Artificial Sequence> cgcauggacaagcccagua
<SEQ ID NO. 2097;RNA;Artificial Sequence> aacugcaccaacgagcugu
<SEQ ID NO. 2098;RNA;Artificial Sequence> uacaugaugaugcgggacu
<SEQ ID NO. 2099;RNA;Artificial Sequence> ugcuggcaugcagugcccu
<SEQ ID NO. 2100;RNA;Artificial Sequence> ucacagagacccaccuuca
<SEQ ID NO. 2101;RNA;Artificial Sequence> aagcagcugguggaagacc
<SEQ ID NO. 2102;RNA;Artificial Sequence> cuggaccgcaucguggccu
<SEQ ID NO. 2103;RNA;Artificial Sequence> uugaccuccaaccaggagu
<SEQ ID NO. 2104;RNA;Artificial Sequence> uaccuggaccuguccaugc
<SEQ ID NO. 2105;RNA;Artificial Sequence> ccccuggaccaguacuccc
<SEQ ID NO. 2106;RNA;Artificial Sequence> cccagcuuucccgacaccc
<SEQ ID NO. 2107;RNA;Artificial Sequence> cggagcucuacgugcuccu
<SEQ ID NO. 2108;RNA;Artificial Sequence> ucaggggaggauuccgucu
<SEQ ID NO. 2109;RNA;Artificial Sequence> uucucucaugagccgcugc
<SEQ ID NO. 21 10;RNA;Artificial Sequence> cccgaggagcccugccugc
<SEQ ID NO. 211 1;RNA;Artificial Sequence> ccccgacacccagcccagc
<SEQ ID NO. 2112;RNA;Artificial Sequence> cuugccaauggcggacuca
<SEQ ID NO. 2113;RNA;Artificial Sequence> aaacgccgcugacugccac
<SEQ ID NO. 2114;RNA;Artificial Sequence> cccacacgcccuccccaga
<SEQ ID NO. 2115;RNA;Artificial Sequence> acuccaccgucagcuguaa
<SEQ ID NO. 2116;RNA;Artificial Sequence> acccucacccacagccccu
<SEQ ID NO. 2117;RNA;Artificial Sequence> ugcugggcccaccaccugu
<SEQ ID NO. 2118;RNA;Artificial Sequence> uccgucccuguccccuuuc
<SEQ ID NO. 2119;RNA;Artificial Sequence> ccugcuggcaggagccggc
<SEQ ID NO. 2120;RNA;Artificial Sequence> cugccuaccaggggccuuc
<SEQ ID NO. 2121;RNA;Artificial Sequence> ccuguguggccugccuuca
<SEQ ID NO. 2122;RNA;Artificial Sequence> accccacucagcucaccuc
<SEQ ID NO. 2123;RNA;Artificial Sequence> cucccuccaccuccucucc
<SEQ ID NO. 2124;RNA; Artificial Sequence> caccugcuggugagaggug
<SEQ ID NO. 2125;RNA;Artificial Sequence> gcaaagaggcagaucuuug
<SEQ ID NO. 2126;RNA;Artificial Sequence> gcugccagccacuucaucc
<SEQ ID NO. 2127;RNA;Artificial Sequence> cccucccagauguuggacc
<SEQ ID NO. 2128;RNA;Artificial Sequence> caacaccccucccugccac
<SEQ ID NO. 2129;RNA;Artificial Sequence> ccaggcacugccuggaggg
<SEQ ID NO. 2130;RNA;Artificial Sequence> gcagggagugggagccaau
<SEQ ID NO. 2131;RNA;Artificial Sequence> ugaacaggcaugcaaguga
<SEQ ID NO. 2132;RNA;Artificial Sequence> agagcuuccugagcuuucu
<SEQ ID NO. 2133;RNA;Artificial Sequence> uccugucgguuuggucugu
<SEQ ID NO. 2134;RNA;Artificial Sequence> uuuugccuucacccauaag
<SEQ ID NO. 2135;RNA; Artificial Sequence> gccccucgcacucuggugg
<SEQ ID NO. 2136;RNA;Artificial Sequence> gcaggugccuuguccucag
<SEQ ID NO. 2137;RNA;Artificial Sequence> gggcuacagcaguagggag
<SEQ ID NO. 2138;RNA;Artificial Sequence> ggucagugcuucgugccuc
<SEQ ID NO. 2139;RNA;Artificial Sequence> cgauugaaggugaccucug
<SEQ ID NO. 2140;RNA;Artificial Sequence> gccccagauagguggugcc
<SEQ ID NO. 2141;RNA;Artificial Sequence> caguggcuuauuaauuccg
<SEQ ID NO. 2142;RNA;Artificial Sequence> gauacuaguuugcuuugcu
<SEQ ID NO. 2143;RNA;Artificial Sequence> ugaccaaaugccugguacc
<SEQ ID NO. 2144;RNA;Artificial Sequence> cagaggauggugaggcgaa
<SEQ ID NO. 2145;RNA;Artificial Sequence> aggccagguugggggcagu
<SEQ ID NO. 2146;RNA;Artificial Sequence> uguuguggcccuggggccc
<SEQ ID NO. 2147;RNA;Artificial Sequence> cagccccaaacugggggcu
<SEQ ID NO. 2148;RNA;Artificial Sequence> ucuguauauagcuaugaag
<SEQ ID NO. 2149;RNA;Artificial Sequence> gaaaacacaaaguguauaa
<SEQ ID NO. 2150;RNA;Artificial Sequence> aaucugaguauauauuuac
<SEQ ID NO. 2151;RNA;Artificial Sequence> caugucuuuuuaaaagggu
<SEQ ID NO. 2152;RNA;Artificial Sequence> ucguuaccagagauuuacc
<SEQ ID NO. 2153;RNA;Artificial Sequence> ccaucggguaagaugcucc
<SEQ ID NO. 2154;RNA;Artificial Sequence> cugguggcugggaggcauc
<SEQ ID NO. 2155;RNA;Artificial Sequence> caguugcuauauauuaaaa
<SEQ ID NO. 2156;RNA;Artificial Sequence> aacaaaaaagaaaaaaaag
<SEQ ID NO. 2157;RNA;Artificial Sequence> ggaaaauguuuuuaaaaag
<SEQ ID NO. 2158;RNA;Artificial Sequence> ggucauauauuuuuugcua
<SEQ ID NO. 2159;RNA; Artificial Sequence> acuuuugcuguuuuauuuu
<SEQ ID NO. 2160;RNA;Artificial Sequence> uuuuaaauuauguucuaaa
<SEQ ID NO. 2161;RNA;Artificial Sequence> accuauuuucaguuuaggu
<SEQ ID NO. 2162;RNA;Artificial Sequence> ucccucaauaaaaauugcu
741-3705

CA 02677068 2009-09-01
<SEQ ID NO. 2163;RNA;Artificial Sequence> ugcugcuucauuuaucuau
<SEQ ID NO. 2164;RNA;Artificial Sequence> ugggcuguaugaaaagggu
<SEQ ID NO. 2165;RNA;Artificial Sequence> ugggaauguccacuggaaa
<SEQ ID NO. 2166;RNA;Artificial Sequence> agaagggacacccacgggc
<SEQ ID NO. 2167;RNA;Artificial Sequence> cccuggggcuaggucuguc
<SEQ ID NO. 2168;RNA;Artificial Sequence> cccgagggcaccgcaugcu
<SEQ ID NO. 2169;RNA;Artificial Sequence> ucccggcgcagguuccuug
<SEQ ID NO. 2170;RNA;Artificial Sequence> guaaccucuucuuccuagg
<SEQ ID NO. 2171;RNA;Artificial Sequence> guccugcacccagaccuca
<SEQ ID NO. 2172;RNA;Artificial Sequence> acgacgcaccuccugccuc
<SEQ ID NO. 2173;RNA;Artificial Sequence> cuccgcugcuuuuggaaag
<SEQ ID NO. 2174;RNA;Artificial Sequence> gucagaaaaagaagauguc
<SEQ ID NO. 2175;RNA;Artificial Sequence> cugcuucgagggcaggaac
<SEQ ID NO. 2176;RNA;Artificial Sequence> ccccauccaugcaguagag
<SEQ ID NO. 2177;RNA;Artificial Sequence> ggcgcugggcagagaguca
<SEQ ID NO. 2178;RNA;Artificial Sequence> aaggcccagcagccaucga
<SEQ ID NO. 2179;RNA;Artificial Sequence> accauggaugguuuccucc
<SEQ ID NO. 2180;RNA;Artificial Sequence> caaggaaaccggugggguu
<SEQ ID NO. 2181;RNA;Artificial Sequence> ugggcuggggagggggcac
<SEQ ID NO. 2182;RNA;Artificial Sequence> ccuaccuaggaauagccac
<SEQ ID NO. 2183;RNA;Artificial Sequence> cgggguagagcuacaguga
<SEQ ID NO. 2184;RNA;Artificial Sequence> auuaagaggaaagcaaggg
<SEQ ID NO. 2185;RNA;Artificial Sequence> gcgcgguugcucacgccug
<SEQ ID NO. 2186;RNA;Artificial Sequence> guaaucccagcacuuuggg
<SEQ ID NO.2187;RNA;Artificial Sequence> gacaccgaggugggcagau
<SEQ ID NO. 2188;RNA;Artificial Sequence> ucacuucaggucaggaguu
<SEQ ID NO. 2189;RNA;Artificial Sequence> uugagaccagccuggccaa
<SEQ ID NO. 2190;RNA;Artificial Sequence> acuuagugaaaccccaucu
<SEQ ID NO. 2191;RNA;Artificial Sequence> ucuacuaaaaaugcaaaaa
<SEQ ID NO. 2192;RNA;Artificial Sequence> auuauccaggcaugguggc
<SEQ ID NO. 2193;RNA;Artificial Sequence> cacacgccuguaaucccag
<SEQ ID NO. 2194;RNA;Artificial Sequence> gcuccacaggaggcugagg
<SEQ ID NO. 2195;RNA;Artificial Sequence> gcagaaucccuugaagcug
<SEQ ID NO. 2196;RNA;Artificial Sequence> gggaggcggagguugcagu
<SEQ ID NO. 2197;RNA;Artificial Sequence> ugagccgagauugcgccau
<SEQ ID NO. 2198;RNA;Artificial Sequence> uugcacuccagccugggca
<SEQ ID NO. 2199;RNA;Artificial Sequence> aacagagaaaacaaaaagg
<SEQ ID NO. 2200;RNA;Artificial Sequence> gaaaacaaaugaugaaggu
<SEQ ID NO. 2201;RNA;Artificial Sequence> ucugcagaaacugaaaccc
<SEQ ID NO. 2202;RNA;Artificial Sequence> cagacaugugucugccccc
<SEQ ID NO. 2203;RNA;Artificial Sequence> cucuaugugggcaugguuu
<SEQ ID NO. 2204;RNA;Artificial Sequence> uugccagugcuucuaagug
<SEQ ID NO. 2205;RNA;Artificial Sequence> gcaggagaacaugucaccu
<SEQ ID NO. 2206;RNA;Artificial Sequence> ugaggcuaguuuugcauuc
<SEQ ID NO. 2207;RNA;Artificial Sequence> caggucccuggcuucguuu
<SEQ ID NO. 2208;RNA;Artificial Sequence> ucuuguugguaugccuccc
<SEQ ID NO. 2209;RNA;Artificial Sequence> ccagaucguccuuccugua
<SEQ ID NO. 2210;RNA;Artificial Sequence> auccaugugaccagacugu
<SEQ ID NO. 221 I;RNA;Artificial Sequence> uauuuguugggacugucgc
<SEQ ID NO. 2212;RNA;Artificial Sequence> cagaucuuggcuucuuaca
<SEQ ID NO. 2213;RNA;Artificial Sequence> aguucuuccuguccaaacu
<SEQ ID NO. 2214;RNA;Artificial Sequence> uccauccugucccucagga
<SEQ ID NO. 2215;RNA;Artificial Sequence> aacggggggaaaauucucc
<SEQ ID NO. 2216;RNA;Artificial Sequence> cgaauguuuuugguuuuuu
<SEQ ID NO. 2217;RNA;Artificial Sequence> uggcugcuuggaauuuacu
<SEQ ID NO. 2218;RNA;Artificial Sequence> uucugccaccugcugguca
<SEQ ID NO. 2219;RNA;Artificial Sequence> aucacuguccucacuaagu
<SEQ ID NO. 2220;RNA;Artificial Sequence> uggauucuggcucccccgu
<SEQ ID NO. 2221;RNA;Artificial Sequence> uaccucauggcucaaacua
<SEQ ID NO. 2222;RNA;Artificial Sequence> accacuccucagucgcuau
<SEQ ID NO. 2223;RNA;Artificial Sequence> uauuaaagcuuauauuuug
<SEQ ID NO. 2224;RNA;Artificial Sequence> gcuggauuacugcuaaaua
<SEQ ID NO. 2225;RNA;Artificial Sequence> acaaaagaaaguucaauau
<SEQ ID NO. 2226;RNA;Artificial Sequence> uguuuucauuucuguaggg
<SEQ ID NO. 2227;RNA;Artificial Sequence> gaaaaugggauugcugcuu
<SEQ ID NO. 2228;RNA; Artificial Sequence> uuaaauuucugagcuaggg
<SEQ ID NO. 2229;RNA;Artificial Sequence> gauuuuuuggcagcugcag
<SEQ ID NO. 2230;RNA;Artificial Sequence> guguuggcgacuauuguaa
<SEQ ID NO. 2231;RNA;Artificial Sequence> aaauucucuuuguuucucu
<SEQ ID NO. 2232;RNA;Artificial Sequence> ucuguaaauagcaccugcu
<SEQ ID NO.2233;RNA;Artificial Sequence> uaacauuacaauuuguauu
<SEQ ID NO. 2234;RNA;Artificial Sequence> uuauguuuaaagaaggcau
<SEQ ID NO. 2235;RNA;Artificial Sequence> ucauuuggugaacagaacu
741-3706

CA 02677068 2009-09-01
<SEQ ID NO. 2236;RNA;Artificial Sequence> uaggaaaugaauuuuuagc
<SEQ ID NO. 2237;RNA;Artificial Sequence> cucuuaaaagcauuugcuu
<SEQ ID NO. 2238;RNA;Artificial Sequence> uugagaccgcacaggagug
<SEQ ID NO. 2239;RNA;Artificial Sequence> gucuuuccuuguaaaacag
<SEQ ID NO. 2240;RNA;Artificial Sequence> gugaugauaauuucugccu
<SEQ ID NO. 2241;RNA;Artificial Sequence> uuggcccuaccuugaagca
<SEQ ID NO. 2242;RNA;Artificial Sequence> aauguugugugaagggaug
<SEQ ID NO. 2243;RNA;Artificial Sequence> gaagaaucuaaaagucuuc
<SEQ ID NO. 2244;RNA;Artificial Sequence> cauaaguccuugggagagg
<SEQ ID NO. 2245;RNA; Artificial Sequence> gugcuagaaaaauauaagg
<SEQ ID NO. 2246;RNA;Artificial Sequence> gcacuaucauaauuacagu
<SEQ ID NO. 2247;RNA;Artificial Sequence> ugauguccuugcuguuacu
<SEQ ID NO. 2248;RNA;Artificial Sequence> uacucaaaucacccacaaa
<SEQ ID NO. 2249;RNA;Artificial Sequence> auuuccccaaagacugcgc
<SEQ ID NO. 2250;RNA;Artificial Sequence> cuagcugucaaauaaaaga
<SEQ ID NO. 2251;RNA;Artificial Sequence> acagugaaauugaccugaa
<SEQ ID NO. 2252;RNA;Artificial Sequence> aagguaaucauggcaccag
<SEQ ID NO. 2253;RNA;Artificial Sequence> gucuucgugggccagucua
<SEQ ID NO. 2254;RNA; Artificial Sequence> acugggaaggagaccacug
<SEQ ID NO. 2255;RNA;Artificial Sequence> gucucgggggcucaaguuc
<SEQ ID NO. 2256;RNA;Artificial Sequence> ccugugggcaggcucaguu
<SEQ ID NO. 2257;RNA;Artificial Sequence> ugcccccgaaugggaucau
<SEQ ID NO. 2258;RNA;Artificial Sequence> uuccucacgcuucaggcac
<SEQ ID NO. 2259;RNA;Artificial Sequence> cacacacuccaucucagua
<SEQ ID NO. 2260;RNA;Artificial Sequence> agggaucuagccacauccc
<SEQ ID NO. 2261;RNA;Artificial Sequence> cccaggacuaguaacagag
<SEQ ID NO. 2262;RNA;Artificial Sequence> ggucacaaaguggagguga
<SEQ ID NO.2263;RNA;Artificial Sequence> agcugggaacagagggcug
<SEQ ID NO. 2264;RNA;Artificial Sequence> gcagggauggguggugcug
<SEQ ID NO. 2265;RNA;Artificial Sequence> ggucuguaauaagcuuuga
<SEQ ID NO. 2266;RNA;Artificial Sequence> agagcaacgucacuggggc
<SEQ ID NO. 2267;RNA;Artificial Sequence> cuuuggggucagcuacaca
<SEQ ID NO. 2268;RNA;Artificial Sequence> aaggaaggcauuuggaccc
<SEQ ID NO. 2269;RNA;Artificial Sequence> ccugccuuuucauugcccg
<SEQ ID NO. 2270;RNA;Artificial Sequence> gaaaccagagccuuuccac
<SEQ ID NO.2271;RNA;Artificial Sequence> ccaagcguuucccagucuu
<SEQ ID NO. 2272;RNA;Artificial Sequence> uagcccuguguccugaguu
<SEQ ID NO. 2273;RNA;Artificial Sequence> uacguacgaucuuucuggc
<SEQ ID NO. 2274;RNA;Artificial Sequence> caaauggggugcaugauaa
<SEQ ID NO. 2275;RNA;Artificial Sequence> agagcaucucuuacgaaga
<SEQ ID NO. 2276;RNA;Artificial Sequence> aguuggaaaaacaaaugcc
<SEQ ID NO. 2277;RNA;Artificial Sequence> cauauauaaauucuaagcc
<SEQ ID NO. 2278;RNA;Artificial Sequence> cauaugaggacgaggagua
<SEQ ID NO. 2279;RNA;Artificial Sequence> aauggcauuuucuuccuuu
<SEQ ID NO. 2280;RNA;Artificial Sequence> uuuccucucacucccagac
<SEQ ID NO. 2281 ;RNA;Artificial Sequence> cauucauugucccugaaug
<SEQ ID NO. 2282;RNA;Artificial Sequence> gcuccauuaauccagggaa
<SEQ ID NO. 2283;RNA;Artificial Sequence> agguaauugccuaaaucuc
<SEQ ID NO. 2284;RNA;Artificial Sequence> ccaguggaucucgcaacag
<SEQ ID NO. 2285;RNA;Artificial Sequence> ggaaggaaccagaagcugg
<SEQ ID NO. 2286;RNA;Artificial Sequence> ggaaaguuguuuaccucuu
<SEQ ID NO. 2287;RNA;Artificial Sequence> uugucccagaguuagaccu
<SEQ ID NO. 2288;RNA;Artificial Sequence> ucauccuccccuagcuuag
<SEQ ID NO. 2289;RNA;Artificial Sequence> gcugucucagagauauacu
<SEQ ID NO. 2290;RNA;Artificial Sequence> uggcccucccuucucuucu
<SEQ ID NO.2291;RNA;Artificial Sequence> ucuuugcugcuggugcuaa
<SEQ ID NO. 2292;RNA;Artificial Sequence> aaacugcucuguaggucau
<SEQ ID NO. 2293;RNA;Artificial Sequence> uuggccacugucuccacuc
<SEQ ID NO. 2294;RNA;Artificial Sequence> cacaaccccugcuccaguc
<SEQ ID NO. 2295;RNA;Artificial Sequence> ccuggagggaguggguuaa
<SEQ ID NO. 2296;RNA;Artificial Sequence> aacacaaauagaacauucc
<SEQ ID NO. 2297;RNA;Artificial Sequence> cauuugaagcagugauucu
<SEQ ID NO. 2298;RNA;Artificial Sequence> uuuaaucaaaugcuuugga
<SEQ ID NO. 2299;RNA;Artificial Sequence> acuuuugaaguccacuugu
<SEQ ID NO. 2300;RNA;Artificial Sequence> uucuguacuuguaaaaggg
<SEQ ID NO. 2301;RNA;Artificial Sequence> gaaagaaggccgggcgcag
<SEQ ID NO. 2302;RNA;Artificial Sequence> guggcucacgccuguaauc
<SEQ ID NO. 2303;RNA;Artificial Sequence> cccagcacuuuagaucacu
<SEQ ID NO. 2304;RNA;Artificial Sequence> uugaggucaggaguuugag
<SEQ ID NO.2305;RNA;Artificial Sequence> gaccagcccggccaacaug
<SEQ ID NO. 2306;RNA;Artificial Sequence> ggugaaaccccaucucuac
<SEQ ID NO. 2307;RNA;Artificial Sequence> cuaaaaauacaaaaauuag
<SEQ ID NO. 2308;RNA;Artificial Sequence> gcugugcauagugguuggc
741-3707

CA 02677068 2009-09-01
<SEQ ID NO. 2309;RNA;Artificial Sequence> caccuguagucccagcuac
<SEQ ID NO.2310;RNA;Artificial Sequence> cucaggaggcugaggcaag
<SEQ ID NO. 2311;RNA;Artificial Sequence> gcuaacugcuugaacccag
<SEQ ID NO. 2312;RNA;Artificial Sequence> gaaggcagagguugcagug
<SEQ ID NO. 2313;RNA;Artificial Sequence> gagcugagaucacgccacu
<SEQ ID NO. 2314;RNA;Artificial Sequence> ugcacuccagccuggguga
<SEQ ID NO. 2315;RNA;Artificial Sequence> acagagugagugagacucu
<SEQ ID NO. 2316;RNA;Artificial Sequence> aucuugaagguaaucaugg
<SEQ ID NO. 2317;RNA;Artificial Sequence> gcaccagucuucgugggcc
<SEQ ID NO. 2318;RNA;Artificial Sequence> cagucuacugggaaggaga
<SEQ ID NO. 2319;RNA;Artificial Sequence> accacugucucgggggcuc
<SEQ ID NO.2320;RNA;Artificial Sequence> caaguuccugugggcaggc
<SEQ ID NO. 2321;RNA;Artificial Sequence> cucaguugcccccgaaugg
<SEQ ID NO. 2322;RNA;Artificial Sequence> ggaucauuccucacgcuuc
<SEQ ID NO. 2323;RNA;Artificial Sequence> caggcacacacacuccauc
<SEQ ID NO.2324;RNA;Artificial Sequence> cucaguagggaucuagcca
<SEQ ID NO. 2325;RNA;Artificial Sequence> acaucccccaggacuagua
<SEQ ID NO. 2326;RNA;Artificial Sequence> aacagaggucacaaagugg
<SEQ ID NO. 2327;RNA;Artificial Sequence> gaggugagcugggaacaga
<SEQ ID NO. 2328;RNA; Artificial Sequence> agggcugcagggaugggug
<SEQ ID NO. 2329;RNA;Artificial Sequence> ggugcuggucuguaauaag
<SEQ ID NO. 2330;RNA;Artificial Sequence> gcuuugagagcaacgucac
<SEQ ID NO. 2331;RNA;Artificial Sequence> cuggggcuuuggggucagc
<SEQ ID NO.2332;RNA;Artificial Sequence> cuacacaaggaaggcauuu
<SEQ ID NO. 2333;RNA;Artificial Sequence> uggaccccugccuuuucau
<SEQ ID NO. 2334;RNA;Artificial Sequence> uugcccgaaaccagagccu
<SEQ ID NO. 2335;RNA;Artificial Sequence> uuuccaccaagcguuuccc
<SEQ ID NO. 2336;RNA;Artificial Sequence> cagucuuagcccugugucc
<SEQ ID NO. 2337;RNA;Artificial Sequence> cugaguuacguacgaucuu
<SEQ ID NO. 2338;RNA;Artificial Sequence> uucuggcaaauggggugca
<SEQ ID NO. 2339;RNA;Artificial Sequence> augauaagagcaucucuua
<SEQ ID NO. 2340;RNA;Artificial Sequence> acgaagaguuggaaaaaca
<SEQ ID NO. 2341;RNA;Artificial Sequence> aaaugccauauauaaauuc
<SEQ ID NO. 2342;RNA;Artificial Sequence> cuaagccauaugaggacga
<SEQ ID NO. 2343;RNA;Artificial Sequence> aggaguaauggcauuuucu
<SEQ ID NO. 2344;RNA;Artificial Sequence> uuccuuuuuccucucacuc
<SEQ ID NO.2345;RNA;Artificial Sequence> cccagacauucauuguccc
<SEQ ID NO. 2346;RNA;Artificial Sequence> cugaaugcuccauuaaucc
<SEQ ID NO. 2347;RNA;Artificial Sequence> cagggaagguaauugccua
<SEQ ID NO. 2348;RNA;Artificial Sequence> aaaucuccaguggaucucg
<SEQ ID NO. 2349;RNA;Artificial Sequence> gcaacaggaaggaaccaga
<SEQ ID NO. 2350;RNA;Artificial Sequence> aagcugggaaaguuguuua
<SEQ ID NO. 2351;RNA;Artificial Sequence> accucuuugucccagaguu
<SEQ ID NO. 2352;RNA;Artificial Sequence> uagaccucauccuccccua
<SEQ ID NO. 2353;RNA;Artificial Sequence> agcuuagcugucucagaga
<SEQ ID NO. 2354;RNA;Artificial Sequence> auauacuggcccucccuuc
<SEQ ID NO. 2355;RNA;Artificial Sequence> cucuucucuuugcugcugg
<SEQ ID NO. 2356;RNA;Artificial Sequence> gugcuaaaacugcucugua
<SEQ ID NO. 2357;RNA;Artificial Sequence> aggucauuggccacugucu
<SEQ ID NO. 2358;RNA;Artificial Sequence> uccacucacaaccccugcu
<SEQ ID NO. 2359;RNA;Artificial Sequence> uccaguccuggagggagug
<SEQ ID NO. 2360;RNA;Artificial Sequence> ggguuaaacacaaauagaa
<SEQ ID NO. 2361;RNA;Artificial Sequence> acauuccauuugaagcagu
<SEQ ID NO. 2362;RNA;Artificial Sequence> uuuuuuuuuaaucaaaugc
<SEQ ID NO. 2363;RNA;Artificial Sequence> cuuuggacuuuugaagucc
<SEQ ID NO. 2364;RNA;Artificial Sequence> cacuuguucuguacuugua
<SEQ ID NO. 2365;RNA;Artificial Sequence> aaaagggaaagaaggccgg
<SEQ ID NO. 2366;RNA;Artificial Sequence> ggcgcaguggcucacgccu
<SEQ ID NO. 2367;RNA;Artificial Sequence> uguaaucccagcacuuuag
<SEQ ID NO. 2368;RNA;Artificial Sequence> gaucacuugaggucaggag
<SEQ ID NO. 2369;RNA;Artificial Sequence> guuugagaccagcccggcc
<SEQ ID NO. 2370;RNA;Artificial Sequence> caacauggugaaaccccau
<SEQ ID NO. 2371;RNA;Artificial Sequence> ucucuacuaaaaauacaaa
<SEQ ID NO. 2372;RNA;Artificial Sequence> aaauuagcugugcauagug
<SEQ ID NO. 2373;RNA;Artificial Sequence> gguuggcaccuguaguccc
<SEQ ID NO. 2374;RNA;Artificial Sequence> cagcuacucaggaggcuga
<SEQ ID NO. 2375;RNA;Artificial Sequence> aggcaagcuaacugcuuga
<SEQ ID NO. 2376;RNA;Artificial Sequence> aacccagaaggcagagguu
<SEQ ID NO. 2377;RNA;Artificial Sequence> ugcagugagcugagaucac
<SEQ ID NO. 2378;RNA;Artificial Sequence> cgccacugcacuccagccu
<SEQ ID NO. 2379;RNA;Artificial Sequence> ugggugacagagugaguga
<SEQ ID NO. 2380;RNA;Artificial Sequence> agacucugcguuaaaaaaa
<SEQ ID NO. 2381;RNA;Artificial Sequence> agaugcaggggcgcaaacgccaaag
741-3708

CA 02677068 2009-09-01
<SEQ ID NO. 2382;RNA;Artificial Sequence> ggagaccaggcuguaggaagagaag
<SEQ ID NO. 2383;RNA;Artificial Sequence> gggcagagcgccggacagcucggcc
<SEQ ID NO.2384;RNA;Artificial Sequence> ccgcuccccguccuuuggggccgcg
<SEQ ID NO. 2385;RNA;Artificial Sequence> ggcuggggaacuacaaggcccagca
<SEQ ID NO. 2386;RNA;Artificial Sequence> aggcagcugcagggggcggaggcgg
<SEQ ID NO. 2387;RNA;Artificial Sequence> gaggagggaccagcgcgggugggag
<SEQ ID NO. 2388;RNA;Artificial Sequence> gugagagagcgagcccucgcgcccc
<SEQ ID NO. 2389;RNA;Artificial Sequence> cgccggcgcauagcgcucggagcgc
<SEQ ID NO. 2390;RNA;Artificial Sequence> cucuugcggccacaggcgcggcguc
<SEQ ID NO. 2391;RNA;Artificial Sequence> ccucggcggcgggcggcagcuagcg
<SEQ ID NO. 2392;RNA;Artificial Sequence> gggagccgggacgccggugcagccg
<SEQ ID NO.2393;RNA;Artificial Sequence> gcagcgcgcggaggaacccgggugu
<SEQ ID NO. 2394;RNA;Artificial Sequence> ugccgggagcugggcggccacgucc
<SEQ ID NO. 2395;RNA;Artificial Sequence> cggacgggaccgagaccccucguag
<SEQ ID NO.2396;RNA;Artificial Sequence> gcgcauugcggcgaccucgccuucc
<SEQ ID NO. 2397;RNA;Artificial Sequence> cccggccgcgagcgcgccgcugcuu
<SEQ ID NO. 2398;RNA;Artificial Sequence> ugaaaagccgcggaacccaaggacu
<SEQ ID NO. 2399;RNA;Artificial Sequence> uuuucuccgguccgagcucggggcg
<SEQ ID NO. 2400;RNA;Artificial Sequence> gccccgcagggcgcacgguacccgu
<SEQ ID NO. 2401;RNA;Artificial Sequence> ugcugcagucgggcacgccgcggcg
<SEQ ID NO. 2402;RNA;Artificial Sequence> gccggggccuccgcagggcgaugga
<SEQ ID NO. 2403;RNA;Artificial Sequence> agcccggucugcaaggaaagugagg
<SEQ ID NO. 2404;RNA;Artificial Sequence> gcgccgccgcugcguucuggaggag
<SEQ ID NO. 2405;RNA;Artificial Sequence> ggggggcacaaggucuggagacccc
<SEQ ID NO. 2406;RNA;Artificial Sequence> cggguggcggacgggagcccucccc
<SEQ ID NO. 2407;RNA;Artificial Sequence> cccgccccgccuccggggcaccagc
<SEQ ID NO. 2408;RNA;Artificial Sequence> cuccggcuccauuguucccgcccgg
<SEQ ID NO. 2409;RNA;Artificial Sequence> ggcuggaggcgccgagcaccgagcg
<SEQ ID NO. 2410;RNA;Artificial Sequence> gccgccgggagucgagcgccggccg
<SEQ ID NO. 2411;RNA;Artificial Sequence> gcggagcucuugcgaccccgccagg
<SEQ ID NO. 2412;RNA;Artificial Sequence> gacccgaacagagcccgggggcggc
<SEQ ID NO. 2413;RNA;Artificial Sequence> cgggccggagccggggacgcgggca
<SEQ ID NO. 2414;RNA;Artificial Sequence> acacgcccgcucgcacaagccacgg
<SEQ ID NO.2415;RNA;Artificial Sequence> gcggacucucccgaggcggaaccuc
<SEQ ID NO. 2416;RNA;Artificial Sequence> ccacgccgagcgagggucaguuuga
<SEQ ID NO. 2417;RNA;Artificial Sequence> aaaaggaggaucgagcucacugugg
<SEQ ID NO. 2418;RNA;Artificial Sequence> gaguauccauggagauguggagccu
<SEQ ID NO. 2419;RNA;Artificial Sequence> uugucaccaaccucuaacugcagaa
<SEQ ID NO.2420;RNA;Artificial Sequence> acugggauguggagcuggaagugcc
<SEQ ID NO. 2421;RNA;Artificial Sequence> cuccucuucugggcugugcugguca
<SEQ ID NO.2422;RNA;Artificial Sequence> acagccacacucugcaccgcuaggc
<SEQ ID NO. 2423;RNA;Artificial Sequence> ccguccccgaccuugccugaacaag
<SEQ ID NO. 2424;RNA;Artificial Sequence> gaugcucuccccuccucggaggaug
<SEQ ID NO. 2425;RNA;Artificial Sequence> gaugaugaugaugaugacuccucuu
<SEQ ID NO. 2426;RNA;Artificial Sequence> ucagaggagaaagaaacagauaaca
<SEQ ID NO. 2427;RNA;Artificial Sequence> accaaaccaaaccccguagcuccau
<SEQ ID NO. 2428;RNA;Artificial Sequence> uauuggacauccccagaaaagaugg
<SEQ ID NO. 2429;RNA;Artificial Sequence> gaaaagaaauugcaugcagugccgg
<SEQ ID NO. 2430;RNA;Artificial Sequence> gcugccaagacagugaaguucaaau
<SEQ ID NO. 2431;RNA;Artificial Sequence> ugcccuuccagugggaccccaaacc
<SEQ ID NO. 2432;RNA;Artificial Sequence> cccacacugcgcugguugaaaaaug
<SEQ ID NO. 2433;RNA;Artificial Sequence> ggcaaagaauucaaaccugaccaca
<SEQ ID NO. 2434;RNA;Artificial Sequence> agaauuggaggcuacaagguccguu
<SEQ ID NO. 2435;RNA;Artificial Sequence> uaugccaccuggagcaucauaaugg
<SEQ ID NO. 2436;RNA;Artificial Sequence> gacucuguggugcccucugacaagg
<SEQ ID NO. 2437;RNA;Artificial Sequence> ggcaacuacaccugcauuguggaga
<SEQ ID NO. 2438;RNA;Artificial Sequence> aaugaguacggcagcaucaaccaca
<SEQ ID NO. 2439;RNA;Artificial Sequence> acauaccagcuggaugucguggagc
<SEQ ID NO. 2440;RNA;Artificial Sequence> cgguccccucaccggcccauccugc
<SEQ ID NO. 2441;RNA;Artificial Sequence> caagcaggguugcccgccaacaaaa
<SEQ ID NO. 2442;RNA;Artificial Sequence> acaguggcccuggguagcaacgugg
<SEQ ID NO. 2443;RNA;Artificial Sequence> gaguucauguguaagguguacagug
<SEQ ID NO. 2444;RNA;Artificial Sequence> gacccgcagccgcacauccaguggc
<SEQ ID NO. 2445;RNA;Artificial Sequence> cuaaagcacaucgaggugaauggga
<SEQ ID NO. 2446;RNA;Artificial Sequence> agcaagauuggcccagacaaccugc
<SEQ ID NO. 2447;RNA;Artificial Sequence> ccuuauguccagaucuugaagacug
<SEQ ID NO. 2448;RNA;Artificial Sequence> gcuggaguuaauaccaccgacaaag
<SEQ ID NO. 2449;RNA;Artificial Sequence> gagauggaggugcuucacuuaagaa
<SEQ ID NO. 2450;RNA;Artificial Sequence> aaugucuccuuugaggacgcagggg
<SEQ ID NO. 2451;RNA;Artificial Sequence> gaguauacgugcuuggcggguaacu
<SEQ ID NO. 2452;RNA;Artificial Sequence> ucuaucggacucucccaucacucug
<SEQ ID NO. 2453;RNA;Artificial Sequence> gcaugguugaccguucuggaagccc
<SEQ ID NO. 2454;RNA;Artificial Sequence> cuggaagagaggccggcagugauga
741-3709

CA 02677068 2009-09-01
<SEQ ID NO. 2455;RNA;Artificial Sequence> accucgccccuguaccuggagauca
<SEQ ID NO. 2456;RNA;Artificial Sequence> aucaucuauugcacaggggccuucc
<SEQ ID NO. 2457;RNA;Artificial Sequence> cucaucuccugcaugguggggucgg
<SEQ ID NO. 2458;RNA;Artificial Sequence> gucaucgucuacaagaugaagagug
<SEQ ID NO. 2459;RNA;Artificial Sequence> gguaccaagaagagugacuuccaca
<SEQ ID NO. 2460;RNA;Artificial Sequence> agccagauggcugugcacaagcugg
<SEQ ID NO. 2461;RNA;Artificial Sequence> gccaagagcaucccucugcgcagac
<SEQ ID NO. 2462;RNA;Artificial Sequence> cagguaacagugucugcugacucca
<SEQ ID NO. 2463;RNA;Artificial Sequence> agugcauccaugaacucugggguuc
<SEQ ID NO. 2464;RNA;Artificial Sequence> cuucugguucggccaucacggcucu
<SEQ ID NO. 2465;RNA;Artificial Sequence> uccuccagugggacucccaugcuag
<SEQ ID NO. 2466;RNA;Artificial Sequence> gcaggggucucugaguaugagcuuc
<SEQ ID NO. 2467;RNA;Artificial Sequence> cccgaagacccucgcugggagcugc
<SEQ ID NO. 2468;RNA;Artificial Sequence> ccucgggacagacuggucuuaggca
<SEQ ID NO. 2469;RNA;Artificial Sequence> aaaccccugggagagggcugcuuug
<SEQ ID NO. 2470;RNA;Artificial Sequence> gggcaggugguguuggcagaggcua
<SEQ ID NO. 2471;RNA;Artificial Sequence> aucgggcuggacaaggacaaaccca
<SEQ ID NO.2472;RNA;Artificial Sequence> aaccgugugaccaaaguggcuguga
<SEQ ID NO. 2473;RNA;Artificial Sequence> aagauguugaagucggacgcaacag
<SEQ ID NO. 2474;RNA;Artificial Sequence> gagaaagacuugucagaccugaucu
<SEQ ID NO.2475;RNA;Artificial Sequence> ucagaaauggagaugaugaagauga
<SEQ ID NO. 2476;RNA;Artificial Sequence> aucgggaagcauaagaauaucauca
<SEQ ID NO. 2477;RNA;Artificial Sequence> aaccugcugggggccugcacgcagg
<SEQ ID NO. 2478;RNA;Artificial Sequence> gauggucccuuguaugucaucgugg
<SEQ ID NO. 2479;RNA;Artificial Sequence> gaguaugccuccaagggcaaccugc
<SEQ ID NO. 2480;RNA;Artificial Sequence> cgggaguaccugcaggcccggaggc
<SEQ ID NO.2481;RNA;Artificial Sequence> cccccagggcuggaauacugcuaca
<SEQ ID NO. 2482;RNA; Artificial Sequence> aaccccagccacaacccagaggagc
<SEQ ID NO. 2483;RNA;Artificial Sequence> cagcucuccuccaaggaccuggugu
<SEQ ID NO. 2484;RNA;Artificial Sequence> uccugcgccuaccagguggcccgag
<SEQ ID NO.2485;RNA;Artificial Sequence> ggcauggaguaucuggccuccaaga
<SEQ ID NO. 2486;RNA;Artificial Sequence> aagugcauacaccgagaccuggcag
<SEQ ID NO. 2487;RNA; Artificial Sequence> gccaggaauguccuggugacagagg
<SEQ ID NO. 2488;RNA;Artificial Sequence> gacaaugugaugaagauagcagacu
<SEQ ID NO. 2489;RNA;Artificial Sequence> uuuggccucgcacgggacauucacc
<SEQ ID NO. 2490;RNA;Artificial Sequence> cacaucgacuacuauaaaaagacaa
<SEQ ID NO. 2491;RNA;Artificial Sequence> accaacggccgacugccugugaagu
<SEQ ID NO. 2492;RNA;Artificial Sequence> uggauggcacccgaggcauuauuug
<SEQ ID NO. 2493;RNA;Artificial Sequence> gaccggaucuacacccaccagagug
<SEQ ID NO. 2494;RNA;Artificial Sequence> gauguguggucuuucggggugcucc
<SEQ ID NO. 2495;RNA;Artificial Sequence> cugugggagaucuucacucugggcg
<SEQ ID NO. 2496;RNA;Artificial Sequence> ggcuccccauaccccggugugccug
<SEQ ID NO. 2497;RNA;Artificial Sequence> guggaggaacuuuucaagcugcuga
<SEQ ID NO. 2498;RNA;Artificial Sequence> aaggagggucaccgcauggacaagc
<SEQ ID NO. 2499;RNA;Artificial Sequence> cccaguaacugcaccaacgagcugu
<SEQ ID NO. 2500;RNA;Artificial Sequence> uacaugaugaugcgggacugcuggc
<SEQ ID NO. 2501;RNA;Artificial Sequence> caugcagugcccucacagagaccca
<SEQ ID NO. 2502;RNA;Artificial Sequence> accuucaagcagcugguggaagacc
<SEQ ID NO. 2503;RNA;Artificial Sequence> cuggaccgcaucguggccuugaccu
<SEQ ID NO. 2504;RNA;Artificial Sequence> uccaaccaggaguaccuggaccugu
<SEQ ID NO. 2505;RNA;Artificial Sequence> uccaugccccuggaccaguacuccc
<SEQ ID NO. 2506;RNA;Artificial Sequence> cccagcuuucccgacacccggagcu
<SEQ ID NO. 2507;RNA;Artificial Sequence> ucuacgugcuccucaggggaggauu
<SEQ ID NO. 2508;RNA;Artificial Sequence> uccgucuucucucaugagccgcugc
<SEQ ID NO. 2509;RNA;Artificial Sequence> cccgaggagcccugccugccccgac
<SEQ ID NO. 2510;RNA;Artificial Sequence> cacccagcccagcuugccaauggcg
<SEQ ID NO.2511;RNA;Artificial Sequence> ggacucaaacgccgcugacugccac
<SEQ ID NO. 2512;RNA;Artificial Sequence> cccacacgcccuccccagacuccac
<SEQ ID NO. 2513;RNA;Artificial Sequence> ccgucagcuguaacccucacccaca
<SEQ ID NO. 2514;RNA;Artificial Sequence> agccccugcugggcccaccaccugu
<SEQ ID NO. 2515;RNA;Artificial Sequence> uccgucccuguccccuuuccugcug
<SEQ ID NO. 2516;RNA;Artificial Sequence> ggcaggagccggcugccuaccaggg
<SEQ ID NO. 2517;RNA;Artificial Sequence> ggccuuccuguguggccugccuuca
<SEQ ID NO. 2518;RNA;Artificial Sequence> accccacucagcucaccucucccuc
<SEQ ID NO. 2519;RNA;Artificial Sequence> ccaccuccucuccaccugcugguga
<SEQ ID NO. 2520;RNA;Artificial Sequence> agaggugcaaagaggcagaucuuug
<SEQ ID NO. 2521;RNA;Artificial Sequence> gcugccagccacuucauccccuccc
<SEQ ID NO. 2522;RNA;Artificial Sequence> cagauguuggaccaacaccccuccc
<SEQ ID NO. 2523;RNA;Artificial Sequence> cugccaccaggcacugccuggaggg
<SEQ ID NO. 2524;RNA;Artificial Sequence> gcagggagugggagccaaugaacag
<SEQ ID NO. 2525;RNA;Artificial Sequence> ggcaugcaagugagagcuuccugag
<SEQ ID NO. 2526;RNA; Artificial Sequence> gcuuucuccugucgguuuggucugu
<SEQ ID NO. 2527;RNA;Artificial Sequence> uuuugccuucacccauaagccccuc
741-3710

CA 02677068 2009-09-01
<SEQ ID NO. 2528;RNA;Artificial Sequence> cgcacucugguggcaggugccuugu
<SEQ ID NO. 2529;RNA;Artificial Sequence> uccucagggcuacagcaguagggag
<SEQ ID NO. 2530;RNA;Artificial Sequence> ggucagugcuucgugccucgauuga
<SEQ ID NO. 2531;RNA;Artificial Sequence> aaggugaccucugccccagauaggu
<SEQ ID NO. 2532;RNA;Artificial Sequence> uggugccaguggcuuauuaauuccg
<SEQ ID NO. 2533;RNA;Artificial Sequence> gauacuaguuugcuuugcugaccaa
<SEQ ID NO. 25 34;RNA; Artificial Sequence> aaugccugguaccagaggaugguga
<SEQ ID NO. 2535;RNA;Artificial Sequence> aggcgaaggccagguugggggcagu
<SEQ ID NO. 2536;RNA;Artificial Sequence> uguuguggcccuggggcccagcccc
<SEQ ID NO. 2537;RNA;Artificial Sequence> caaacugggggcucuguauauagcu
<SEQ ID NO. 2538;RNA;Artificial Sequence> uaugaagaaaacacaaaguguauaa
<SEQ ID NO. 2539;RNA;Artificial Sequence> aaucugaguauauauuuacaugucu
<SEQ ID NO. 2540;RNA;Artificial Sequence> uuuuuaaaagggucguuaccagaga
<SEQ ID NO. 2541;RNA;Artificial Sequence> auuuacccaucggguaagaugcucc
<SEQ ID NO. 2542;RNA; Artificial Sequence> cugguggcugggaggcaucaguugc
<SEQ ID NO. 2543;RNA;Artificial Sequence> cuauauauuaaaaacaaaaaagaaa
<SEQ ID NO. 2544;RNA;Artificial Sequence> aaaaaaggaaaauguuuuuaaaaag
<SEQ ID NO. 2545;RNA;Artificial Sequence> ggucauauauuuuuugcuacuuuug
<SEQ ID NO. 2546;RNA;Artificial Sequence> gcuguuuuauuuuuuuaaauuaugu
<SEQ ID NO. 2547;RNA;Artificial Sequence> uucuaaaccuauuuucaguuuaggu
<SEQ ID NO. 2548;RNA;Artificial Sequence> ucccucaauaaaaauugcugcugcu
<SEQ ID NO.2549;RNA;Artificial Sequence> uucauuuaucuaugggcuguaugaa
<SEQ ID NO. 2550;RNA; Artificial Sequence> aaagggugggaauguccacuggaaa
<SEQ ID NO. 2551;RNA;Artificial Sequence> agaagggacacccacgggcccuggg
<SEQ ID NO. 2552;RNA;Artificial Sequence> ggcuaggucugucccgagggcaccg
<SEQ ID NO. 2553;RNA;Artificial Sequence> gcaugcucccggcgcagguuccuug
<SEQ ID NO. 2554;RNA;Artificial Sequence> guaaccucuucuuccuagguccugc
<SEQ ID NO. 2555;RNA;Artificial Sequence> cacccagaccucacgacgcaccucc
<SEQ ID NO. 2556;RNA;Artificial Sequence> cugccucuccgcugcuuuuggaaag
<SEQ ID NO. 2557;RNA;Artificial Sequence> gucagaaaaagaagaugucugcuuc
<SEQ ID NO. 2558;RNA;Artificial Sequence> cgagggcaggaaccccauccaugca
<SEQ ID NO. 2559;RNA;Artificial Sequence> aguagaggcgcugggcagagaguca
<SEQ ID NO. 2560;RNA;Artificial Sequence> aaggcccagcagccaucgaccaugg
<SEQ ID NO. 2561;RNA;Artificial Sequence> gaugguuuccuccaaggaaaccggu
<SEQ ID NO. 2562;RNA;Artificial Sequence> ugggguugggcuggggagggggcac
<SEQ ID NO. 2563;RNA;Artificial Sequence> ccuaccuaggaauagccacggggua
<SEQ ID NO. 2564;RNA;Artificial Sequence> agagcuacagugauuaagaggaaag
<SEQ ID NO. 2565;RNA;Artificial Sequence> gcaagggcgcgguugcucacgccug
<SEQ ID NO. 2566;RNA;Artificial Sequence> guaaucccagcacuuugggacaccg
<SEQ ID NO. 2567;RNA;Artificial Sequence> gaggugggcagaucacuucagguca
<SEQ ID NO. 2568;RNA;Artificial Sequence> aggaguuugagaccagccuggccaa
<SEQ ID NO. 2569;RNA;Artificial Sequence> acuuagugaaaccccaucucuacua
<SEQ ID NO. 2570;RNA;Artificial Sequence> aaaaaugcaaaaauuauccaggcau
<SEQ ID NO. 2571;RNA;Artificial Sequence> ugguggcacacgccuguaaucccag
<SEQ ID NO. 2572;RNA;Artificial Sequence> gcuccacaggaggcugaggcagaau
<SEQ ID NO. 2573;RNA;Artificial Sequence> ucccuugaagcugggaggcggaggu
<SEQ ID NO. 2574;RNA;Artificial Sequence> uugcagugagccgagauugcgccau
<SEQ ID NO. 2575;RNA;Artificial Sequence> uugcacuccagccugggcaacagag
<SEQ ID NO. 2576;RNA;Artificial Sequence> gaaaacaaaaaggaaaacaaaugau
<SEQ ID NO. 2577;RNA;Artificial Sequence> ugaaggucugcagaaacugaaaccc
<SEQ ID NO. 2578;RNA;Artificial Sequence> cagacaugugucugcccccucuaug
<SEQ ID NO. 2579;RNA;Artificial Sequence> gugggcaugguuuugccagugcuuc
<SEQ ID NO. 2580;RNA;Artificial Sequence> cuaagugcaggagaacaugucaccu
<SEQ ID NO. 2581;RNA;Artificial Sequence> ugaggcuaguuuugcauucaggucc
<SEQ ID NO. 2582;RNA;Artificial Sequence> ccuggcuucguuucuuguugguaug
<SEQ ID NO. 2583;RNA;Artificial Sequence> gccuccccagaucguccuuccugua
<SEQ ID NO. 2584;RNA;Artificial Sequence> auccaugugaccagacuguauuugu
<SEQ ID NO. 2585;RNA;Artificial Sequence> uugggacugucgcagaucuuggcuu
<SEQ ID NO. 2586;RNA;Artificial Sequence> ucuuacaguucuuccuguccaaacu
<SEQ ID NO. 2587;RNA;Artificial Sequence> uccauccugucccucaggaacgggg
<SEQ ID NO. 2588;RNA;Artificial Sequence> gggaaaauucuccgaauguuuuugg
<SEQ ID NO. 2589;RNA;Artificial Sequence> guuuuuuggcugcuuggaauuuacu
<SEQ ID NO. 2590;RNA;Artificial Sequence> uucugccaccugcuggucaucacug
<SEQ ID NO. 2591;RNA;Artificial Sequence> guccucacuaaguggauucuggcuc
<SEQ ID NO. 2592;RNA;Artificial Sequence> cccccguaccucauggcucaaacua
<SEQ ID NO. 2593;RNA;Artificial Sequence> accacuccucagucgcuauauuaaa
<SEQ ID NO. 2594;RNA;Artificial Sequence> agcuuauauuuugcuggauuacugc
<SEQ ID NO. 2595;RNA;Artificial Sequence> cuaaauacaaaagaaaguucaauau
<SEQ ID NO. 2596;RNA;Artificial Sequence> uguuuucauuucuguagggaaaaug
<SEQ ID NO. 2597;RNA;Artificial Sequence> gggauugcugcuuuaaauuucugag
<SEQ ID NO. 2598;RNA;Artificial Sequence> gcuagggauuuuuuggcagcugcag
<SEQ ID NO. 2599;RNA;Artificial Sequence> guguuggcgacuauuguaaaauucu
<SEQ ID NO. 2600;RNA;Artificial Sequence> ucuuuguuucucucuguaaauagca
741-3711

CA 02677068 2009-09-01
<SEQ ID NO. 2601;RNA;Artificial Sequence> accugcuaacauuacaauuuguauu
<SEQ ID NO. 2602;RNA;Artificial Sequence> uuauguuuaaagaaggcaucauuug
<SEQ ID NO. 2603;RNA;Artificial Sequence> ggugaacagaacuaggaaaugaauu
<SEQ ID NO. 2604;RNA;Artificial Sequence> uuuuagcucuuaaaagcauuugcuu
<SEQ ID NO. 2605;RNA;Artificial Sequence> uugagaccgcacaggagugucuuuc
<SEQ ID NO. 2606;RNA;Artificial Sequence> ccuuguaaaacagugaugauaauuu
<SEQ ID NO. 2607;RNA;Artificial Sequence> ucugccuuggcccuaccuugaagca
<SEQ ID NO. 2608;RNA;Artificial Sequence> aauguugugugaagggaugaagaau
<SEQ ID NO. 2609;RNA;Artificial Sequence> ucuaaaagucuucauaaguccuugg
<SEQ ID NO. 2610;RNA;Artificial Sequence> ggagaggugcuagaaaaauauaagg
<SEQ ID NO. 261 1;RNA;Artificial Sequence> gcacuaucauaauuacagugauguc
<SEQ ID NO. 2612;RNA;Artificial Sequence> ccuugcuguuacuacucaaaucacc
<SEQ ID NO.2613;RNA;Artificial Sequence> ccacaaauuuccccaaagacugcgc
<SEQ ID NO. 2614;RNA;Artificial Sequence> cuagcugucaaauaaaagacaguga
<SEQ ID NO. 2615;RNA;Artificial Sequence> gcccagcccuggggagccccugugg
<SEQ ID NO.2616;RNA;Artificial Sequence> gaaguggaguccuuccugguccacc
<SEQ ID NO.2617;RNA;Artificial Sequence> cccggugaccugcugcagcuucgcu
<SEQ ID NO. 2618;RNA;Artificial Sequence> ugucggcugcgggacgaugugcaga
<SEQ ID NO. 2619;RNA;Artificial Sequence> agcaucaacuggcugcgggacgggg
<SEQ ID NO. 2620;RNA;Artificial Sequence> gugcagcuggcggaaagcaaccgca
<SEQ ID NO. 2621;RNA;Artificial Sequence> acccgcaucacaggggaggaggugg
<SEQ ID NO. 2622;RNA;Artificial Sequence> gaggugcaggacuccgugcccgcag
<SEQ ID NO. 2623;RNA;Artificial Sequence> gacuccggccucuaugcuugcguaa
<SEQ ID NO. 2624;RNA;Artificial Sequence> accagcagccccucgggcagugaca
<SEQ ID NO. 2625;RNA;Artificial Sequence> accaccuacuucuccgucaauguuu
<SEQ ID NO. 2626;RNA;Artificial Sequence> ucagaugcucuccccuccucggagg
<SEQ ID NO. 2627;RNA;Artificial Sequence> gaugaugaugaugaugaugacuccu
<SEQ ID NO. 2628;RNA;Artificial Sequence> ucuucagaggagaaagaaacagaua
<SEQ ID NO. 2629;RNA;Artificial Sequence> aacaccaaaccaaaccccguagcuc
<SEQ ID NO. 2630;RNA;Artificial Sequence> ccauauuggacauccccagaaaaga
<SEQ ID NO. 263 1;RNA;Artificial Sequence> auggaaaagaaauugcaugcagugc
<SEQ ID NO. 2632;RNA;Artificial Sequence> ccggcugccaagacagugaaguuca
<SEQ ID NO. 2633;RNA;Artificial Sequence> aaaugcccuuccagugggaccccaa
<SEQ ID NO. 2634;RNA;Artificial Sequence> aaccccacacugcgcugguugaaaa
<SEQ ID NO. 2635;RNA;Artificial Sequence> aauggcaaagaauucaaaccugacc
<SEQ ID NO. 2636;RNA;Artificial Sequence> cacagaauuggaggcuacaaggucc
<SEQ ID NO. 2637;RNA;Artificial Sequence> cguuaugccaccuggagcaucauaa
<SEQ ID NO.2638;RNA;Artificial Sequence> auggacucuguggugcccucugaca
<SEQ ID NO. 2639;RNA;Artificial Sequence> aagggcaacuacaccugcauugugg
<SEQ ID NO. 2640;RNA;Artificial Sequence> gagaaugaguacggcagcaucaacc
<SEQ ID NO. 2641;RNA;Artificial Sequence> cacacauaccagcuggaugucgugg
<SEQ ID NO. 2642;RNA;Artificial Sequence> gagcgguccccucaccggcccaucc
<SEQ ID NO.2643;RNA;Artificial Sequence> cugcaagcaggguugcccgccaaca
<SEQ ID NO. 2644;RNA;Artificial Sequence> aaaacaguggcccuggguagcaacg
<SEQ ID NO. 2645;RNA;Artificial Sequence> guggaguucauguguaagguguaca
<SEQ ID NO. 2646;RNA;Artificial Sequence> agugacccgcagccgcacauccagu
<SEQ ID NO. 2647;RNA;Artificial Sequence> uggcuaaagcacaucgaggugaaug
<SEQ ID NO. 2648;RNA;Artificial Sequence> gggagcaagauuggcccagacaacc
<SEQ ID NO. 2649;RNA;Artificial Sequence> cugccuuauguccagaucuugaaga
<SEQ ID NO. 2650;RNA;Artificial Sequence> acugcuggaguuaauaccaccgaca
<SEQ ID NO. 265 1;RNA;Artificial Sequence> aaagagauggaggugcuucacuuaa
<SEQ ID NO. 2652;RNA;Artificial Sequence> agaaaugucuccuuugaggacgcag
<SEQ ID NO. 2653;RNA;Artificial Sequence> ggggaguauacgugcuuggcgggua
<SEQ ID NO. 2654;RNA;Artificial Sequence> aacucuaucggacucucccaucacu
<SEQ ID NO. 2655;RNA;Artificial Sequence> ucugcaugguugaccguucuggaag
<SEQ ID NO. 2656;RNA;Artificial Sequence> gcccuggaagagaggccggcaguga
<SEQ ID NO. 2657;RNA;Artificial Sequence> augaccucgccccuguaccuggaga
<SEQ ID NO. 2658;RNA;Artificial Sequence> aucaucaucuauugcacaggggccu
<SEQ ID NO. 2659;RNA;Artificial Sequence> uuccucaucuccugcaugguggggu
<SEQ ID NO. 2660;RNA;Artificial Sequence> ucggucaucgucuacaagaugaaga
<SEQ ID NO. 2661;RNA;Artificial Sequence> agugguaccaagaagagugacuucc
<SEQ ID NO. 2662;RNA;Artificial Sequence> cacagccagauggcugugcacaagc
<SEQ ID NO. 2663;RNA;Artificial Sequence> cuggccaagagcaucccucugcgca
<SEQ ID NO. 2664;RNA;Artificial Sequence> agacagguaacagugucugcugacu
<SEQ ID NO. 2665;RNA;Artificial Sequence> uccagugcauccaugaacucugggg
<SEQ ID NO. 2666;RNA;Artificial Sequence> guucuucugguucggccaucacggc
<SEQ ID NO. 2667;RNA;Artificial Sequence> cucuccuccagugggacucccaugc
<SEQ ID NO.2668;RNA;Artificial Sequence> cuagcaggggucucugaguaugagc
<SEQ ID NO. 2669;RNA;Artificial Sequence> cuucccgaagacccucgcugggagc
<SEQ ID NO. 2670;RNA;Artificial Sequence> cugccucgggacagacuggucuuag
<SEQ ID NO. 2671;RNA;Artificial Sequence> ggcaaaccccugggagagggcugcu
<SEQ ID NO. 2672;RNA;Artificial Sequence> uuugggcaggugguguuggcagagg
<SEQ ID NO. 2673;RNA;Artificial Sequence> gcuaucgggcuggacaaggacaaac
741-3712

CA 02677068 2009-09-01
<SEQ ID NO. 2674;RNA;Artificial Sequence> cccaaccgugugaccaaaguggcug
<SEQ ID NO. 2675;RNA;Artificial Sequence> gugaagauguugaagucggacgcaa
<SEQ ID NO. 2676;RNA;Artificial Sequence> acagagaaagacuugucagaccuga
<SEQ ID NO. 2677;RNA;Artificial Sequence> aucucagaaauggagaugaugaaga
<SEQ ID NO. 2678;RNA;Artificial Sequence> augaucgggaagcauaagaauauca
<SEQ ID NO. 2679;RNA;Artificial Sequence> aucaaccugcugggggccugcacgc
<SEQ ID NO. 2680;RNA;Artificial Sequence> caggauggucccuuguaugucaucg
<SEQ ID NO. 2681;RNA;Artificial Sequence> guggaguaugccuccaagggcaacc
<SEQ ID NO. 2682;RNA;Artificial Sequence> cugcgggaguaccugcaggcccgga
<SEQ ID NO. 2683;RNA;Artificial Sequence> aggcccccagggcuggaauacugcu
<SEQ ID NO. 2684;RNA;Artificial Sequence> uacaaccccagccacaacccagagg
<SEQ ID NO. 2685;RNA;Artificial Sequence> gagcagcucuccuccaaggaccugg
<SEQ ID NO. 2686;RNA;Artificial Sequence> guguccugcgccuaccagguggccc
<SEQ ID NO.2687;RNA;Artificial Sequence> cgaggcauggaguaucuggccucca
<SEQ ID NO. 268 8;RNA; Artificial Sequence> aagaagugcauacaccgagaccugg
<SEQ ID NO. 2689;RNA;Artificial Sequence> gcagccaggaauguccuggugacag
<SEQ ID NO. 2690;RNA;Artificial Sequence> gaggacaaugugaugaagauagcag
<SEQ ID NO. 2691;RNA;Artificial Sequence> gacuuuggccucgcacgggacauuc
<SEQ ID NO. 2692;RNA;Artificial Sequence> caccacaucgacuacuauaaaaaga
<SEQ ID NO. 2693;RNA;Artificial Sequence> acaaccaacggccgacugccuguga
<SEQ ID NO. 2694;RNA;Artificial Sequence> aaguggauggcacccgaggcauuau
<SEQ ID NO. 2695;RNA;Artificial Sequence> uuugaccggaucuacacccaccaga
<SEQ ID NO. 2696;RNA;Artificial Sequence> agugauguguggucuuucggggugc
<SEQ ID NO. 2697;RNA;Artificial Sequence> cuccugugggagaucuucacucugg
<SEQ ID NO. 2698;RNA;Artificial Sequence> ggcggcuccccauaccccggugugc
<SEQ ID NO. 2699;RNA;Artificial Sequence> ccuguggaggaacuuuucaagcugc
<SEQ ID NO. 2700;RNA;Artificial Sequence> cugaaggagggucaccgcauggaca
<SEQ ID NO. 2701;RNA;Artificial Sequence> aagcccaguaacugcaccaacgagc
<SEQ ID NO. 2702;RNA;Artificial Sequence> cuguacaugaugaugcgggacugcu
<SEQ ID NO. 2703;RNA;Artificial Sequence> uggcaugcagugcccucacagagac
<SEQ ID NO. 2704;RNA;Artificial Sequence> cccaccuucaagcagcugguggaag
<SEQ ID NO. 2705;RNA;Artificial Sequence> gaccuggaccgcaucguggccuuga
<SEQ ID NO.2706;RNA;Artificial Sequence> accuccaaccaggaguaccuggacc
<SEQ ID NO. 2707;RNA;Artificial Sequence> cuguccaugccccuggaccaguacu
<SEQ ID NO. 2708;RNA; Artificial Sequence> ucccccagcuuucccgacacccgga
<SEQ ID NO. 2709;RNA;Artificial Sequence> agcucuacgugcuccucaggggagg
<SEQ ID NO.2710;RNA;Artificial Sequence> gauuccgucuucucucaugagccgc
<SEQ ID NO. 271 1;RNA;Artificial Sequence> cugcccgaggagcccugccugcccc
<SEQ ID NO. 2712;RNA;Artificial Sequence> cgacacccagcccagcuugccaaug
<SEQ ID NO. 2713;RNA;Artificial Sequence> ggcggacucaaacgccgcugacugc
<SEQ ID NO. 2714;RNA;Artificial Sequence> ccacccacacgcccuccccagacuc
<SEQ ID NO. 2715;RNA;Artificial Sequence> ccaccgucagcuguaacccucaccc
<SEQ ID NO. 2716;RNA;Artificial Sequence> cacagccccugcugggcccaccacc
<SEQ ID NO. 2717;RNA;Artificial Sequence> cuguccgucccuguccccuuuccug
<SEQ ID NO. 2718;RNA;Artificial Sequence> gcuggcaggagccggcugccuacca
<SEQ ID NO. 2719;RNA;Artificial Sequence> aggggecuuccuguguggccugccu
<SEQ ID NO. 2720;RNA;Artificial Sequence> uucaccccacucagcucaccucucc
<SEQ ID NO. 2721;RNA;Artificial Sequence> ccuccaccuccucuccaccugcugg
<SEQ ID NO.2722;RNA;Artificial Sequence> gugagaggugcaaagaggcagaucu
<SEQ ID NO. 2723;RNA;Artificial Sequence> uuugcugccagccacuucauccccu
<SEQ ID NO. 2724;RNA;Artificial Sequence> ucccagauguuggaccaacaccccu
<SEQ ID NO.2725;RNA;Artificial Sequence> ucccugccaccaggcacugccugga
<SEQ ID NO. 2726;RNA;Artificial Sequence> agggcagggagugggagccaaugaa
<SEQ ID NO. 2727;RNA;Artificial Sequence> acaggcaugcaagugagagcuuccu
<SEQ ID NO. 2728;RNA;Artificial Sequence> ugagcuuucuccugucgguuugguc
<SEQ ID NO. 2729;RNA;Artificial Sequence> cuguuuugccuucacccauaagccc
<SEQ ID NO. 2730;RNA;Artificial Sequence> ccucgcacucugguggcaggugccu
<SEQ ID NO. 2731;RNA;Artificial Sequence> uuguccucagggcuacagcaguagg
<SEQ ID NO. 2732;RNA;Artificial Sequence> ggaggucagugcuucgugccucgau
<SEQ ID NO.2733;RNA;Artificial Sequence> uugaaggugaccucugccccagaua
<SEQ ID NO. 2734;RNA;Artificial Sequence> agguggugccaguggcuuauuaauu
<SEQ ID NO. 2735;RNA;Artificial Sequence> uccgauacuaguuugcuuugcugac
<SEQ ID NO. 2736;RNA;Artificial Sequence> ccaaaugccugguaccagaggaugg
<SEQ ID NO. 2737;RNA;Artificial Sequence> gugaggcgaaggccagguugggggc
<SEQ ID NO. 2738;RNA;Artificial Sequence> caguguuguggcccuggggcccagc
<SEQ ID NO. 2739;RNA;Artificial Sequence> ccccaaacugggggcucuguauaua
<SEQ ID NO. 2740;RNA;Artificial Sequence> agcuaugaagaaaacacaaagugua
<SEQ ID NO.2741;RNA;Artificial Sequence> auaaaucugaguauauauuuacaug
<SEQ ID NO.2742;RNA;Artificial Sequence> gucuuuuuaaaagggucguuaccag
<SEQ ID NO. 2743;RNA;Artificial Sequence> gagauuuacccaucggguaagaugc
<SEQ ID NO. 2744;RNA;Artificial Sequence> cuccugguggcugggaggcaucagu
<SEQ ID NO. 2745;RNA;Artificial Sequence> uugcuauauauuaaaaacaaaaaag
<SEQ ID NO. 2746;RNA;Artificial Sequence> gaaaaaaaaggaaaauguuuuuaaa
741-3713

CA 02677068 2009-09-01
<SEQ ID NO. 2747;RNA;Artificial Sequence> aaaggucauauauuuuuugcuacuu
<SEQ ID NO. 2748;RNA;Artificial Sequence> uuugcuguuuuauuuuuuuaaauua
<SEQ ID NO. 2749;RNA;Artificial Sequence> auguucuaaaccuauuuucaguuua
<SEQ ID NO. 2750;RNA;Artificial Sequence> aggucccucaauaaaaauugcugcu
<SEQ ID NO. 2751;RNA;Artificial Sequence> ugcuucauuuaucuaugggcuguau
<SEQ ID NO. 2752;RNA;Artificial Sequence> ugaaaagggugggaauguccacugg
<SEQ ID NO.2753;RNA;Artificial Sequence> gaaagaagggacacccacgggcccu
<SEQ ID NO. 2754;RNA;Artificial Sequence> uggggcuaggucugucccgagggca
<SEQ ID NO. 2755;RNA;Artificial Sequence> accgcaugcucccggcgcagguucc
<SEQ ID NO. 2756;RNA;Artificial Sequence> cuuguaaccucuucuuccuaggucc
<SEQ ID NO. 2757;RNA;Artificial Sequence> cugcacccagaccucacgacgcacc
<SEQ ID NO. 2758;RNA;Artificial Sequence> cuccugccucuccgcugcuuuugga
<SEQ ID NO. 2759;RNA;Artificial Sequence> aaagucagaaaaagaagaugucugc
<SEQ ID NO. 2760;RNA;Artificial Sequence> cuucgagggcaggaaccccauccau
<SEQ ID NO. 2761;RNA;Artificial Sequence> ugcaguagaggcgcugggcagagag
<SEQ ID NO. 2762;RNA;Artificial Sequence> gucaaggcccagcagccaucgacca
<SEQ ID NO. 2763;RNA;Artificial Sequence> auggaugguuuccuccaaggaaacc
<SEQ ID NO. 2764;RNA;Artificial Sequence> cggugggguugggcuggggaggggg
<SEQ ID NO. 2765;RNA;Artificial Sequence> gcaccuaccuaggaauagccacggg
<SEQ ID NO. 2766;RNA;Artificial Sequence> gguagagcuacagugauuaagagga
<SEQ ID NO. 2767;RNA;Artificial Sequence> aaagcaagggcgcgguugcucacgc
<SEQ ID NO.2768;RNA;Artificial Sequence> ccuguaaucccagcacuuugggaca
<SEQ ID NO. 2769;RNA;Artificial Sequence> accgaggugggcagaucacuucagg
<SEQ ID NO. 2770;RNA;Artificial Sequence> gucaggaguuugagaccagccuggc
<SEQ ID NO. 2771;RNA;Artificial Sequence> ccaacuuagugaaaccccaucucua
<SEQ ID NO. 2772;RNA;Artificial Sequence> acuaaaaaugcaaaaauuauccagg
<SEQ ID NO. 2773;RNA;Artificial Sequence> gcaugguggcacacgccuguaaucc
<SEQ ID NO. 2774;RNA;Artificial Sequence> ccagcuccacaggaggcugaggcag
<SEQ ID NO. 2775;RNA;Artificial Sequence> gaaucccuugaagcugggaggcgga
<SEQ ID NO. 2776;RNA;Artificial Sequence> agguugcagugagccgagauugcgc
<SEQ ID NO. 2777;RNA;Artificial Sequence> ccauugcacuccagccugggcaaca
<SEQ ID NO. 2778;RNA;Artificial Sequence> agagaaaacaaaaaggaaaacaaau
<SEQ ID NO.2779;RNA;Artificial Sequence> ugaugaaggucugcagaaacugaaa
<SEQ ID NO. 2780;RNA;Artificial Sequence> acccagacaugugucugcccccucu
<SEQ ID NO. 278 1;RNA;Artificial Sequence> uaugugggcaugguuuugccagugc
<SEQ ID NO. 2782;RNA;Artificial Sequence> cuucuaagugcaggagaacauguca
<SEQ ID NO. 2783;RNA;Artificial Sequence> accugaggcuaguuuugcauucagg
<SEQ ID NO. 2784;RNA;Artificial Sequence> gucccuggcuucguuucuuguuggu
<SEQ ID NO. 2785;RNA;Artificial Sequence> uaugccuccccagaucguccuuccu
<SEQ ID NO. 2786;RNA;Artificial Sequence> uguauccaugugaccagacuguauu
<SEQ ID NO.2787;RNA;Artificial Sequence> uuguugggacugucgcagaucuugg
<SEQ ID NO.2788;RNA;Artificial Sequence> gcuucuuacaguucuuccuguccaa
<SEQ ID NO. 2789;RNA;Artificial Sequence> aacuccauccugucccucaggaacg
<SEQ ID NO. 2790;RNA;Artificial Sequence> ggggggaaaauucuccgaauguuuu
<SEQ ID NO. 2791;RNA;Artificial Sequence> uugguuuuuuggcugcuuggaauuu
<SEQ ID NO. 2792;RNA;Artificial Sequence> uacuucugccaccugcuggucauca
<SEQ ID NO. 2793;RNA;Artificial Sequence> acuguccucacuaaguggauucugg
<SEQ ID NO. 2794;RNA;Artificial Sequence> gcucccccguaccucauggcucaaa
<SEQ ID NO. 2795;RNA;Artificial Sequence> acuaccacuccucagucgcuauauu
<SEQ ID NO. 2796;RNA;Artificial Sequence> uaaagcuuauauuuugcuggauuac
<SEQ ID NO. 2797;RNA;Artificial Sequence> cugcuaaauacaaaagaaaguucaa
<SEQ ID NO. 2798;RNA;Artificial Sequence> auauguuuucauuucuguagggaaa
<SEQ ID NO. 2799;RNA;Artificial Sequence> aaugggauugcugcuuuaaauuucu
<SEQ ID NO. 2800;RNA;Artificial Sequence> ugagcuagggauuuuuuggcagcug
<SEQ ID NO. 2801;RNA;Artificial Sequence> gcaguguuggcgacuauuguaaaau
<SEQ ID NO. 2802;RNA;Artificial Sequence> uucucuuuguuucucucuguaaaua
<SEQ ID NO. 2803;RNA;Artificial Sequence> agcaccugcuaacauuacaauuugu
<SEQ ID NO. 2804;RNA;Artificial Sequence> uauuuauguuuaaagaaggcaucau
<SEQ ID NO. 2805;RNA;Artificial Sequence> uuuggugaacagaacuaggaaauga
<SEQ ID NO. 2806;RNA;Artificial Sequence> aauuuuuagcucuuaaaagcauuug
<SEQ ID NO. 2807;RNA;Artificial Sequence> gcuuugagaccgcacaggagugucu
<SEQ ID NO. 2808;RNA;Artificial Sequence> uuuccuuguaaaacagugaugauaa
<SEQ ID NO. 2809;RNA;Artificial Sequence> auuucugccuuggcccuaccuugaa
<SEQ ID NO. 2810;RNA;Artificial Sequence> agcaauguugugugaagggaugaag
<SEQ ID NO. 281 1;RNA;Artificial Sequence> gaaucuaaaagucuucauaaguccu
<SEQ ID NO. 2812;RNA;Artificial Sequence> uugggagaggugcuagaaaaauaua
<SEQ ID NO. 2813;RNA;Artificial Sequence> aaggcacuaucauaauuacagugau
<SEQ ID NO.2814;RNA;Artifcial Sequence> uguccuugcuguuacuacucaaauc
<SEQ ID NO. 2815;RNA;Artificial Sequence> cacccacaaauuuccccaaagacug
<SEQ ID NO. 2816;RNA;Artificial Sequence> gcgcuagcugucaaauaaaagacag
<SEQ ID NO. 2817;RNA;Artificial Sequence> aacaccaaaccaaaccguaugcccg
<SEQ ID NO. 2818;RNA;Artificial Sequence> guagcuccauauuggacauccccag
<SEQ ID NO. 2819;RNA;Artificial Sequence> gaaaagauggaaaagaaauugcaug
741-3714

CA 02677068 2009-09-01
<SEQ ID NO. 2820;RNA;Artificial Sequence> gcagugccggcugccaagacaguga
<SEQ ID NO.2821;RNA;Artificial Sequence> aaguucaaaugcccuuccaguggga
<SEQ ID NO. 2822;RNA;Artificial Sequence> accccaaaccccacacugcgcuggu
<SEQ ID NO. 2823;RNA;Artificial Sequence> uugaaaaauggcaaagaauucaaac
<SEQ ID NO. 2824;RNA;Artificial Sequence> ccugaccacagaauuggaggcuaca
<SEQ ID NO. 2825;RNA;Artificial Sequence> aagguccguuaugccaccuggagca
<SEQ ID NO. 2826;RNA;Artificial Sequence> aucauaauggacucuguggugcccu
<SEQ ID NO. 2827;RNA;Artificial Sequence> ucugacaagggcaacuacaccugca
<SEQ ID NO. 2828;RNA;Artificial Sequence> auuguggagaaugaguacggcagca
<SEQ ID NO.2829;RNA;Artificial Sequence> aucaaccacacauaccagcuggaug
<SEQ ID NO. 2830;RNA;Artificial Sequence> gucguggagcgguccccucaccggc
<SEQ ID NO. 2831;RNA;Artificial Sequence> cccauccugcaagcaggguugcccg
<SEQ ID NO. 2832;RNA;Artificial Sequence> gccaacaaaacaguggcccugggua
<SEQ ID NO. 2833;RNA;Artificial Sequence> agcaacguggaguucauguguaagg
<SEQ ID NO. 2834;RNA;Artificial Sequence> guguacagugacccgcagccgcaca
<SEQ ID NO. 2835;RNA;Artificial Sequence> auccaguggcuaaagcacaucgagg
<SEQ ID NO. 2836;RNA;Artificial Sequence> gugaaugggagcaagauuggcccag
<SEQ ID NO. 2837;RNA;Artificial Sequence> gacaaccugccuuauguccagaucu
<SEQ ID NO.2838;RNA;Artificial Sequence> uugaagacugcuggaguuaauacca
<SEQ ID NO. 2 839;RNA; Artificial Sequence> accgacaaagagauggaggugcuuc
<SEQ ID NO. 2840;RNA;Artificial Sequence> cacuuaagaaaugucuccuuugagg
<SEQ ID NO. 2841;RNA;Artificial Sequence> gacgcaggggaguauacgugcuugg
<SEQ ID NO. 2842;RNA;Artificial Sequence> gcggguaacucuaucggacucuccc
<SEQ ID NO. 2843;RNA;Artificial Sequence> caucacucugcaugguugaccguuc
<SEQ ID NO. 2844;RNA;Artificial Sequence> cuggaagcccuggaagagaggccgg
<SEQ ID NO. 2845;RNA;Artificial Sequence> gcagugaugaccucgccccuguacc
<SEQ ID NO. 2846;RNA;Artificial Sequence> cuggagaucaucaucuauugcacag
<SEQ ID NO. 2847;RNA;Artificial Sequence> ggggccuuccucaucuccugcaugg
<SEQ ID NO. 2848;RNA;Artificial Sequence> guggggucggucaucgucuacaaga
<SEQ ID NO. 2 849;RNA; Artificial Sequence> augaagagugguaccaagaagagug
<SEQ ID NO. 2850;RNA;Artificial Sequence> gacuuccacagccagauggcugugc
<SEQ ID NO. 2851;RNA;Artificial Sequence> cacaagcuggccaagagcaucccuc
<SEQ ID NO. 2852;RNA;Artificial Sequence> cugcgcagacagguaacagugucug
<SEQ ID NO. 2853;RNA;Artificial Sequence> gcugacuccagugcauccaugaacu
<SEQ ID NO. 2854;RNA;Artificial Sequence> ucugggguucuucugguucggccau
<SEQ ID NO. 2855;RNA;Artificial Sequence> ucacggcucuccuccagugggacuc
<SEQ ID NO. 2856;RNA;Artificial Sequence> cccaugcuagcaggggucucugagu
<SEQ ID NO. 2857;RNA;Artificial Sequence> uaugagcuucccgaagacccucgcu
<SEQ ID NO. 2858;RNA;Artificial Sequence> ugggagcugccucgggacagacugg
<SEQ ID NO. 2859;RNA;Artificial Sequence> gucuuaggcaaaccccugggagagg
<SEQ ID NO.2860;RNA;Artificial Sequence> ggcugcuuugggcaggugguguugg
<SEQ ID NO.2861;RNA;Artificial Sequence> gcagaggcuaucgggcuggacaagg
<SEQ ID NO. 2862;RNA;Artificial Sequence> gacaaacccaaccgugugaccaaag
<SEQ ID NO. 2863;RNA;Artificial Sequence> guggcugugaagauguugaagucgg
<SEQ ID NO. 2864;RNA;Artificial Sequence> gacgcaacagagaaagacuugucag
<SEQ ID NO. 2865;RNA;Artificial Sequence> gaccugaucucagaaauggagauga
<SEQ ID NO. 2866;RNA;Artificial Sequence> augaagaugaucgggaagcauaaga
<SEQ ID NO. 2867;RNA;Artificial Sequence> aauaucaucaaccugcugggggccu
<SEQ ID NO. 2868;RNA;Artificial Sequence> ugcacgcaggauggucccuuguaug
<SEQ ID NO. 2869;RNA;Artificial Sequence> gucaucguggaguaugccuccaagg
<SEQ ID NO. 2870;RNA;Artificial Sequence> ggcaaccugcgggaguaccugcagg
<SEQ ID NO. 2871;RNA;Artificial Sequence> gcccggaggcccccagggcuggaau
<SEQ ID NO. 2872;RNA;Artificial Sequence> uacugcuacaaccccagccacaacc
<SEQ ID NO. 2873;RNA;Artificial Sequence> ccagaggagcagcucuccuccaagg
<SEQ ID NO. 2874;RNA;Artificial Sequence> gaccugguguccugcgccuaccagg
<SEQ ID NO. 2875;RNA;Artificial Sequence> guggcccgaggcauggaguaucugg
<SEQ ID NO. 2876;RNA;Artificial Sequence> gccuccaagaagugcauacaccgag
<SEQ ID NO. 2877;RNA;Artificial Sequence> gaccuggcagccaggaauguccugg
<SEQ ID NO. 2878;RNA;Artificial Sequence> gugacagaggacaaugugaugaaga
<SEQ ID NO. 2879;RNA;Artificial Sequence> auagcagacuuuggccucgcacggg
<SEQ ID NO. 2880;RNA;Artificial Sequence> gacauucaccacaucgacuacuaua
<SEQ ID NO. 2881;RNA;Artificial Sequence> aaaaagacaaccaacggccgacugc
<SEQ ID NO. 2882;RNA;Artificial Sequence> ccugugaaguggauggcacccgagg
<SEQ ID NO. 2883;RNA;Artificial Sequence> gcauuauuugaccggaucuacaccc
<SEQ ID NO. 2884;RNA;Artificial Sequence> caccagagugauguguggucuuucg
<SEQ ID NO. 2885;RNA;Artificial Sequence> ggggugcuccugugggagaucuuca
<SEQ ID NO. 2886;RNA;Artificial Sequence> acucugggcggcuccccauaccccg
<SEQ ID NO. 2887;RNA;Artificial Sequence> ggugugccuguggaggaacuuuuca
<SEQ ID NO. 2888;RNA;Artificial Sequence> aagcugcugaaggagggucaccgca
<SEQ ID NO. 2889;RNA;Artificial Sequence> auggacaagcccaguaacugcacca
<SEQ ID NO. 2890;RNA;Artificial Sequence> aacgagcuguacaugaugaugcggg
<SEQ ID NO. 2891;RNA;Artificial Sequence> gacugcuggcaugcagugcccucac
<SEQ ID NO. 2892;RNA;Artificial Sequence> cagagacccaccuucaagcagcugg
741-3715

CA 02677068 2009-09-01
<SEQ ID NO. 2893;RNA;Artificial Sequence> guggaagaccuggaccgcaucgugg
<SEQ ID NO. 2894;RNA;Artificial Sequence> gccuugaccuccaaccaggaguacc
<SEQ ID NO. 2895;RNA;Artificial Sequence> cuggaccuguccaugccccuggacc
<SEQ ID NO. 2896;RNA;Artificial Sequence> caguacucccccagcuuucccgaca
<SEQ ID NO. 2897;RNA;Artificial Sequence> acccggagcucuacgugcuccucag
<SEQ ID NO. 2898;RNA;Artificial Sequence> ggggaggauuccgucuucucucaug
<SEQ ID NO. 2899;RNA;Artificial Sequence> gagccgcugcccgaggagcccugcc
<SEQ ID NO. 2900;RNA;Artificial Sequence> cugccccgacacccagcccagcuug
<SEQ ID NO. 2901;RNA;Artificial Sequence> gccaauggcggacucaaacgccgcu
<SEQ ID NO. 2902;RNA;Artificial Sequence> ugacugccacccacacgcccucccc
<SEQ ID NO. 2903;RNA;Artificial Sequence> cagacuccaccgucagcuguaaccc
<SEQ ID NO. 2904;RNA;Artificial Sequence> cucacccacagccccugcugggccc
<SEQ ID NO. 2905;RNA;Artificial Sequence> caccaccuguccgucccuguccccu
<SEQ ID NO. 2906;RNA;Artificial Sequence> uuuccugcuggcaggagccggcugc
<SEQ ID NO. 2907;RNA;Artificial Sequence> ccuaccaggggccuuccuguguggc
<SEQ ID NO. 2908;RNA;Artificial Sequence> ccugccuucaccccacucagcucac
<SEQ ID NO. 2909;RNA;Artificial Sequence> ccucucccuccaccuccucuccacc
<SEQ ID NO. 2910;RNA;Artificial Sequence> cugcuggugagaggugcaaagaggc
<SEQ ID NO. 291 l ;RNA;Artificial Sequence> cagaucuuugcugccagccacuuca
<SEQ ID NO. 2912;RNA;Artificial Sequence> auccccucccagauguuggaccaac
<SEQ ID NO. 2913;RNA;Artificial Sequence> caccccucccugccaccaggcacug
<SEQ ID NO.2914;RNA;Artificial Sequence> gccuggagggcagggagugggagcc
<SEQ ID NO. 2915;RNA;Artificial Sequence> caaugaacaggcaugcaagugagag
<SEQ ID NO. 2916;RNA;Artificial Sequence> gcuuccugagcuuucuccugucggu
<SEQ ID NO. 2917;RNA;Artificial Sequence> uuuggucuguuuugccuucacccau
<SEQ ID NO. 2918;RNA;Artificial Sequence> uaagccccucgcacucugguggcag
<SEQ ID NO. 2919;RNA;Artificial Sequence> ggugccuuguccucagggcuacagc
<SEQ ID NO. 2920;RNA;Artificial Sequence> caguagggaggucagugcuucgugc
<SEQ ID NO. 2921;RNA;Artificial Sequence> ccucgauugaaggugaccucugccc
<SEQ ID NO. 2922;RNA;Artificial Sequence> ccagauagguggugccaguggcuua
<SEQ ID NO. 2923;RNA;Artificial Sequence> auuaauuccgauacuaguuugcuuu
<SEQ ID NO. 2924;RNA;Artificial Sequence> ugcugaccaaaugccugguaccaga
<SEQ ID NO. 2925;RNA;Artificial Sequence> aggauggugaggcgaaggccagguu
<SEQ ID NO. 2926;RNA;Artificial Sequence> ugggggcaguguuguggcccugggg
<SEQ ID NO. 2927;RNA;Artificial Sequence> gcccagccccaaacugggggcucug
<SEQ ID NO. 2928;RNA; Artificial Sequence> guauauagcuaugaagaaaacacaa
<SEQ ID NO.2929;RNA;Artificial Sequence> aaguguauaaaucugaguauauauu
<SEQ ID NO. 2930;RNA;Artificial Sequence> uuacaugucuuuuuaaaagggucgu
<SEQ ID NO. 2931;RNA;Artificial Sequence> uuaccagagauuuacccaucgggua
<SEQ ID NO. 2932;RNA;Artificial Sequence> aagaugcuccugguggcugggaggc
<SEQ ID NO. 2933;RNA;Artificial Sequence> caucaguugcuauauauuaaaaaca
<SEQ ID NO. 2934;RNA;Artificial Sequence> aaaaaagaaaaaaaaggaaaauguu
<SEQ ID NO. 2935;RNA; Artificial Sequence> uuuuaaaaaggucauauauuuuuug
<SEQ ID NO. 2936;RNA;Artificial Sequence> gcuacuuuugcuguuuuauuuuuuu
<SEQ ID NO. 2937;RNA;Artificial Sequence> uaaauuauguucuaaaccuauuuuc
<SEQ ID NO. 2938;RNA;Artificial Sequence> caguuuaggucccucaauaaaaauu
<SEQ ID NO. 2939;RNA;Artificial Sequence> ugcugcugcuucauuuaucuauggg
<SEQ ID NO. 2940;RNA;Artificial Sequence> gcuguaugaaaagggugggaauguc
<SEQ ID NO. 2941;RNA;Artificial Sequence> ccacuggaaagaagggacacccacg
<SEQ ID NO. 2942;RNA;Artificial Sequence> gggcccuggggcuaggucugucccg
<SEQ ID NO. 2943;RNA;Artificial Sequence> gagggcaccgcaugcucceggcgca
<SEQ ID NO. 2944;RNA;Artificial Sequence> agguuccuuguaaccucuucuuccu
<SEQ ID NO. 2945;RNA;Artificial Sequence> uagguccugcacccagaccucacga
<SEQ ID NO. 2946;RNA;Artificial Sequence> acgcaccuccugccucuccgcugcu
<SEQ ID NO. 2947;RNA;Artificial Sequence> uuuuggaaagucagaaaaagaagau
<SEQ ID NO. 2948;RNA;Artificial Sequence> ugucugcuucgagggcaggaacccc
<SEQ ID NO. 2949;RNA;Artificial Sequence> cauccaugcaguagaggcgcugggc
<SEQ ID NO. 2950;RNA;Artificial Sequence> cagagagucaaggcccagcagccau
<SEQ ID NO. 2951;RNA;Artificial Sequence> ucgaccauggaugguuuccuccaag
<SEQ ID NO. 2952;RNA;Artificial Sequence> ggaaaccggugggguugggcugggg
<SEQ ID NO. 2953;RNA;Artificial Sequence> gagggggcaccuaccuaggaauagc
<SEQ ID NO. 2954;RNA;Artificial Sequence> ccacgggguagagcuacagugauua
<SEQ ID NO. 2955;RNA;Artificial Sequence> aagaggaaagcaagggcgcgguugc
<SEQ ID NO. 2956;RNA;Artificial Sequence> cucacgccuguaaucccagcacuuu
<SEQ ID NO. 2957;RNA;Artificial Sequence> ugggacaccgaggugggcagaucac
<SEQ ID NO. 2958;RNA;Artificial Sequence> cuucaggucaggaguuugagaccag
<SEQ ID NO. 2959;RNA;Artificial Sequence> gccuggccaacuuagugaaacccca
<SEQ ID NO.2960;RNA;Artificial Sequence> aucucuacuaaaaaugcaaaaauua
<SEQ ID NO. 2961;RNA;Artificial Sequence> auccaggcaugguggcacacgccug
<SEQ ID NO. 2962;RNA;Artificial Sequence> guaaucccagcuccacaggaggcug
<SEQ ID NO. 2963;RNA;Artificial Sequence> gaggcagaaucccuugaagcuggga
<SEQ ID NO.2964;RNA;Artificial Sequence> aggcggagguugcagugagccgaga
<SEQ ID NO. 2965;RNA;Artificial Sequence> auugcgccauugcacuccagccugg
741-3716

CA 02677068 2009-09-01
<SEQ ID NO. 2966;RNA;Artificial Sequence> ggcaacagagaaaacaaaaaggaaa
<SEQ ID NO. 2967;RNA;Artificial Sequence> aacaaaugaugaaggucugcagaaa
<SEQ ID NO. 2968;RNA;Artificial Sequence> acugaaacccagacaugugucugcc
<SEQ ID NO. 2969;RNA;Artificial Sequence> ccccucuaugugggcaugguuuugc
<SEQ ID NO.2970;RNA;Artificial Sequence> ccagugcuucuaagugcaggagaac
<SEQ ID NO. 2971;RNA;Artificial Sequence> caugucaccugaggcuaguuuugca
<SEQ ID NO. 2972;RNA;Artificial Sequence> auucaggucccuggcuucguuucuu
<SEQ ID NO. 2973;RNA;Artificial Sequence> uguugguaugccuccccagaucguc
<SEQ ID NO. 2974;RNA;Artificial Sequence> ccuuccuguauccaugugaccagac
<SEQ ID NO. 2975;RNA;Artificial Sequence> cuguauuuguugggacugucgcaga
<SEQ ID NO. 2976;RNA;Artificial Sequence> aucuuggcuucuuacaguucuuccu
<SEQ ID NO. 2977;RNA;Artificial Sequence> uguccaaacuccauccugucccuca
<SEQ ID NO. 2978;RNA;Artificial Sequence> aggaacggggggaaaauucuccgaa
<SEQ ID NO. 2979;RNA;Artificial Sequence> auguuuuugguuuuuuggcugcuug
<SEQ ID NO. 2980;RNA;Artificial Sequence> ggaauuuacuucugccaccugcugg
<SEQ ID NO. 2981;RNA;Artificial Sequence> gucaucacuguccucacuaagugga
<SEQ ID NO. 2982;RNA;Artificial Sequence> auucuggcucccccguaccucaugg
<SEQ ID NO. 2983;RNA;Artificial Sequence> gcucaaacuaccacuccucagucgc
<SEQ ID NO.2984;RNA;Artificial Sequence> cuauauuaaagcuuauauuuugcug
<SEQ ID NO. 2985;RNA;Artificial Sequence> ggauuacugcuaaauacaaaagaaa
<SEQ ID NO. 2986;RNA;Artificial Sequence> aguucaauauguuuucauuucugua
<SEQ ID NO. 2987;RNA;Artificial Sequence> agggaaaaugggauugcugcuuuaa
<SEQ ID NO. 2988;RNA;Artificial Sequence> aauuucugagcuagggauuuuuugg
<SEQ ID NO. 2989;RNA;Artificial Sequence> gcagcugcaguguuggcgacuauug
<SEQ ID NO. 2990;RNA;Artificial Sequence> guaaaauucucuuuguuucucucug
<SEQ ID NO. 2991;RNA;Artificial Sequence> guaaauagcaccugcuaacauuaca
<SEQ ID NO. 2992;RNA;Artificial Sequence> aauuuguauuuauguuuaaagaagg
<SEQ ID NO. 2993;RNA;Artificial Sequence> gcaucauuuggugaacagaacuagg
<SEQ ID NO. 2994;RNA;Artificial Sequence> gaaaugaauuuuuagcucuuaaaag
<SEQ ID NO. 2995;RNA;Artificial Sequence> gcauuugcuuugagaccgcacagga
<SEQ ID NO. 2996;RNA;Artificial Sequence> agugucuuuccuuguaaaacaguga
<SEQ ID NO. 2997;RNA;Artificial Sequence> augauaauuucugccuuggcccuac
<SEQ ID NO.2998;RNA;Artificial Sequence> ccuugaagcaauguugugugaaggg
<SEQ ID NO. 2999;RNA;Artificial Sequence> gaugaagaaucuaaaagucuucaua
<SEQ ID NO. 3000;RNA;Artificial Sequence> aaguccuugggagaggugcuagaaa
<SEQ ID NO. 3001;RNA;Artificial Sequence> aaauauaaggcacuaucauaauuac
<SEQ ID NO. 3002;RNA;Artificial Sequence> cagugauguccuugcuguuacuacu
<SEQ ID NO. 3003;RNA;Artificial Sequence> ucaaaucacccacaaauuuccccaa
<SEQ ID NO. 3004;RNA;Artificial Sequence> aagacugcgcuagcugucaaauaaa
<SEQ ID NO. 3005;RNA;Artificial Sequence> aagacagugaaauugaccugaaaaa
<SEQ ID NO. 3006;RNA;Artificial Sequence> aagcagcugguggaagaccuggacc
<SEQ ID NO. 3007;RNA;Artificial Sequence> cgcaucguggccuugaccuccaacc
<SEQ ID NO. 3008;RNA;Artificial Sequence> caggaguaccuggaccuguccaugc
<SEQ ID NO. 3009;RNA;Artificial Sequence> ccccuggaccaguacucccccagcu
<SEQ ID NO. 3010;RNA;Artificial Sequence> uuucccgacacccggagcucuacgu
<SEQ ID NO. 301 1;RNA;Artificial Sequence> ugcuccucaggggaggauuccgucu
<SEQ ID NO. 3012;RNA;Artificial Sequence> uucucucaugagccgcugcccgagg
<SEQ ID NO. 3013;RNA;Artificial Sequence> gagcccugccugccccgacacccag
<SEQ ID NO. 3014;RNA;Artificial Sequence> gcccagcuugccaauggcggacuca
<SEQ ID NO. 3015;RNA;Artificial Sequence> aaacgccgcugacugccacccacac
<SEQ ID NO. 3016;RNA;Artificial Sequence> cgcccuccccagacuccaccgucag
<SEQ ID NO. 3017;RNA;Artificial Sequence> gcuguaacccucacccacagccccu
<SEQ ID NO. 3018;RNA;Artificial Sequence> ugcugggcccaccaccuguccgucc
<SEQ ID NO. 3019;RNA;Artificial Sequence> ccuguccccuuuccugcuggcagga
<SEQ ID NO. 3020;RNA;Artificial Sequence> agccggcugccuaccaggggccuuc
<SEQ ID NO. 3021;RNA;Artificial Sequence> ccuguguggccugccuucaccccac
<SEQ ID NO. 3022;RNA;Artificial Sequence> cucagcucaccucucccuccaccuc
<SEQ ID NO. 3023;RNA;Artificial Sequence> ccucuccaccugcuggugagaggug
<SEQ ID NO. 3024;RNA;Artificial Sequence> gcaaagaggcagaucuuugcugcca
<SEQ ID NO. 3025;RNA;Artificial Sequence> agccacuucauccccucccagaugu
<SEQ ID NO. 3026;RNA;Artificial Sequence> uuggaccaacaccccucccugccac
<SEQ ID NO. 3027;RNA;Artificial Sequence> ccaggcacugccuggagggcaggga
<SEQ ID NO. 3028;RNA;Artificial Sequence> agugggagccaaugaacaggcaugc
<SEQ ID NO. 3029;RNA;Artificial Sequence> caagugagagcuuccugagcuuucu
<SEQ ID NO. 3030;RNA;Artificial Sequence> uccugucgguuuggucuguuuugcc
<SEQ ID NO. 3031;RNA;Artificial Sequence> cuucacccauaagccccucgcacuc
<SEQ ID NO. 3032;RNA;Artificial Sequence> cugguggcaggugccuuguccucag
<SEQ ID NO. 3033;RNA;Artificial Sequence> gggcuacagcaguagggaggucagu
<SEQ ID NO. 3034;RNA;Artificial Sequence> ugcuucgugccucgauugaagguga
<SEQ ID NO. 3035;RNA;Artificial Sequence> accucugccccagauagguggugcc
<SEQ ID NO. 3036;RNA;Artificial Sequence> caguggcuuauuaauuccgauacua
<SEQ ID NO. 3037;RNA;Artificial Sequence> aguuugcuuugcugaccaaaugccu
<SEQ ID NO. 3038;RNA;Artificial Sequence> ugguaccagaggauggugaggcgaa
741-3717

CA 02677068 2009-09-01
<SEQ ID NO. 3039;RNA;Artificial Sequence> aggccagguugggggcaguguugug
<SEQ ID NO. 3040;RNA;Artificial Sequence> ggcccuggggcccagccccaaacug
<SEQ ID NO. 3041;RNA;Artificial Sequence> gggggcucuguauauagcuaugaag
<SEQ ID NO. 3042;RNA;Artificial Sequence> gaaaacacaaaguguauaaaucuga
<SEQ ID NO. 3043;RNA;Artificial Sequence> aguauauauuuacaugucuuuuuaa
<SEQ ID NO. 3044;RNA;Artificial Sequence> aaagggucguuaccagagauuuacc
<SEQ ID NO. 3045;RNA;Artificial Sequence> ccaucggguaagaugcuccuggugg
<SEQ ID NO. 3046;RNA;Artificial Sequence> gcugggaggcaucaguugcuauaua
<SEQ ID NO. 3047;RNA;Artificial Sequence> auuaaaaacaaaaaagaaaaaaaag
<SEQ ID NO. 3048;RNA;Artificial Sequence> ggaaaauguuuuuaaaaaggucaua
<SEQ ID NO. 3049;RNA;Artificial Sequence> auauuuuuugcuacuuuugcuguuu
<SEQ ID NO. 3050;RNA;Artificial Sequence> uuauuuuuuuaaauuauguucuaaa
<SEQ ID NO. 3051;RNA;Artificial Sequence> accuauuuucaguuuaggucccuca
<SEQ ID NO. 3052;RNA;Artificial Sequence> aauaaaaauugcugcugcuucauuu
<SEQ ID NO. 3053;RNA;Artificial Sequence> uaucuaugggcuguaugaaaagggu
<SEQ ID NO. 3054;RNA;Artificial Sequence> ugggaauguccacuggaaagaaggg
<SEQ ID NO. 3055;RNA;Artificial Sequence> gacacccacgggcccuggggcuagg
<SEQ ID NO. 3056;RNA;Artificial Sequence> gucugucccgagggcaccgcaugcu
<SEQ ID NO. 3057;RNA;Artificial Sequence> ucccggcgcagguuccuuguaaccu
<SEQ ID NO. 3058;RNA;Artificial Sequence> ucuucuuccuagguccugcacccag
<SEQ ID NO. 3059;RNA;Artificial Sequence> gaccucacgacgcaccuccugccuc
<SEQ ID NO. 3060;RNA;Artificial Sequence> cuccgcugcuuuuggaaagucagaa
<SEQ ID NO. 3061;RNA;Artificial Sequence> aaaagaagaugucugcuucgagggc
<SEQ ID NO. 3062;RNA;Artificial Sequence> caggaaccccauccaugcaguagag
<SEQ ID NO. 3063;RNA;Artificial Sequence> ggcgcugggcagagagucaaggccc
<SEQ ID NO. 3064;RNA;Artificial Sequence> cagcagccaucgaccauggaugguu
<SEQ ID NO. 3065;RNA;Artificial Sequence> uuccuccaaggaaaccggugggguu
<SEQ ID NO. 3066;RNA;Artificial Sequence> ugggcuggggagggggcaccuaccu
<SEQ ID NO. 3067;RNA;Artificial Sequence> uaggaauagccacgggguagagcua
<SEQ ID NO. 3068;RNA;Artificial Sequence> acagugauuaagaggaaagcaaggg
<SEQ ID NO. 3069;RNA;Artificial Sequence> gcgcgguugcucacgccuguaaucc
<SEQ ID NO. 3070;RNA;Artificial Sequence> ccagcacuuugggacaccgaggugg
<SEQ ID NO. 3071;RNA;Artificial Sequence> ggcagaucacuucaggucaggaguu
<SEQ ID NO. 3072;RNA;Artificial Sequence> uugagaccagccuggccaacuuagu
<SEQ ID NO. 3073;RNA;Artificial Sequence> ugaaaccccaucucuacuaaaaaug
<SEQ ID NO. 3074;RNA;Artificial Sequence> gcaaaaauuauccaggcaugguggc
<SEQ ID NO. 3075;RNA;Artificial Sequence> cacacgccuguaaucccagcuccac
<SEQ ID NO. 3076;RNA;Artificial Sequence> caggaggcugaggcagaaucccuug
<SEQ ID NO. 3077;RNA;Artificial Sequence> gaagcugggaggcggagguugcagu
<SEQ ID NO. 3078;RNA;Artificial Sequence> ugagccgagauugcgccauugcacu
<SEQ ID NO. 3079;RNA;Artificial Sequence> uccagecugggcaacagagaaaaca
<SEQ ID NO. 3080;RNA;Artificial Sequence> aaaaaggaaaacaaaugaugaaggu
<SEQ ID NO. 3081;RNA;Artificial Sequence> ucugcagaaacugaaacccagacau
<SEQ ID NO. 3082;RNA;Artificial Sequence> ugugucugcccccucuaugugggca
<SEQ ID NO. 3083;RNA;Artificial Sequence> augguuuugccagugcuucuaagug
<SEQ ID NO.3084;RNA;Artificial Sequence> gcaggagaacaugucaccugaggcu
<SEQ ID NO. 3085;RNA;Artificial Sequence> uaguuuugcauucaggucccuggcu
<SEQ ID NO. 3086;RNA;Artificial Sequence> uucguuucuuguugguaugccuccc
<SEQ ID NO. 3087;RNA;Artificial Sequence> ccagaucguccuuccuguauccaug
<SEQ ID NO. 3088;RNA;Artificial Sequence> gugaccagacuguauuuguugggac
<SEQ ID NO. 3089;RNA;Artificial Sequence> cugucgcagaucuuggcuucuuaca
<SEQ ID NO. 3090;RNA;Artificial Sequence> aguucuuccuguccaaacuccaucc
<SEQ ID NO. 3091;RNA;Artificial Sequence> cugucccucaggaacggggggaaaa
<SEQ ID NO. 3092;RNA;Artificial Sequence> auucuccgaauguuuuugguuuuuu
<SEQ ID NO. 3093;RNA;Artificial Sequence> uggcugcuuggaauuuacuucugcc
<SEQ ID NO. 3094;RNA;Artificial Sequence> caccugcuggucaucacuguccuca
<SEQ ID NO. 3095;RNA;Artificial Sequence> acuaaguggauucuggcucccccgu
<SEQ ID NO. 3096;RNA;Artificial Sequence> uaccucauggcucaaacuaccacuc
<SEQ ID NO. 3097;RNA;Artificial Sequence> ccucagucgcuauauuaaagcuuau
<SEQ ID NO. 3098;RNA;Artificial Sequence> uauuuugcuggauuacugcuaaaua
<SEQ ID NO. 3099;RNA;Artificial Sequence> acaaaagaaaguucaauauguuuuc
<SEQ ID NO. 3100;RNA;Artificial Sequence> cauuucuguagggaaaaugggauug
<SEQ ID NO. 3101;RNA;Artificial Sequence> gcugcuuuaaauuucugagcuaggg
<SEQ ID NO. 3102;RNA;Artificial Sequence> gauuuuuuggcagcugcaguguugg
<SEQ ID NO. 3103;RNA;Artificial Sequence> gcgacuauuguaaaauucucuuugu
<SEQ ID NO. 3104;RNA;Artificial Sequence> uuucucucuguaaauagcaccugcu
<SEQ ID NO. 3105;RNA;Artificial Sequence> uaacauuacaauuuguauuuauguu
<SEQ ID NO. 3106;RNA;Artificial Sequence> uuaaagaaggcaucauuuggugaac
<SEQ ID NO. 3107;RNA;Artificial Sequence> cagaacuaggaaaugaauuuuuagc
<SEQ ID NO. 3108;RNA;Artificial Sequence> cucuuaaaagcauuugcuuugagac
<SEQ ID NO. 3109;RNA;Artificial Sequence> ccgcacaggagugucuuuccuugua
<SEQ ID NO. 31 10;RNA;Artificial Sequence> aaaacagugaugauaauuucugccu
<SEQ ID NO. 3111;RNA;Artificial Sequence> uuggcccuaccuugaagcaauguug
741-3718

CA 02677068 2009-09-01
<SEQ ID NO. 3112;RNA;Artificial Sequence> gugugaagggaugaagaaucuaaaa
<SEQ ID NO. 3113;RNA;Artificial Sequence> agucuucauaaguccuugggagagg
<SEQ ID NO. 3114;RNA;Artificial Sequence> gugcuagaaaaauauaaggcacuau
<SEQ ID NO. 3115;RNA;Artificial Sequence> ucauaauuacagugauguccuugcu
<SEQ ID NO. 3116;RNA;Artificial Sequence> uguuacuacucaaaucacccacaaa
<SEQ ID NO. 3117;RNA;Artificial Sequence> auuuccccaaagacugcgcuagcug
<SEQ ID NO. 3118;RNA;Artificial Sequence> gucaaauaaaagacagugaaauuga
<SEQ ID NO. 3119;RNA;Artificial Sequence> accaaaccaaaccguaugcccguag
<SEQ ID NO. 3120;RNA;Artificial Sequence> gcuccauauuggacauccccagaaa
<SEQ ID NO. 3121;RNA;Artificial Sequence> aagauggaaaagaaauugcaugcag
<SEQ ID NO. 3122;RNA;Artificial Sequence> gugccggcugccaagacagugaagu
<SEQ ID NO. 3123;RNA;Artificial Sequence> uucaaaugcccuuccagugggaccc
<SEQ ID NO.3124;RNA;Artificial Sequence> ccaaaccccacacugcgcugguuga
<SEQ ID NO. 3125;RNA;Artificial Sequence> aaaaauggcaaagaauucaaaccug
<SEQ ID NO. 3126;RNA;Artificial Sequence> gaccacagaauuggaggcuacaagg
<SEQ ID NO. 3127;RNA;Artificial Sequence> guccguuaugccaccuggagcauca
<SEQ ID NO. 3128;RNA;Artificial Sequence> auaauggacucuguggugcccucug
<SEQ ID NO. 3129;RNA;Artificial Sequence> gacaagggcaacuacaccugcauug
<SEQ ID NO. 3130;RNA;Artificial Sequence> guggagaaugaguacggcagcauca
<SEQ ID NO. 3131;RNA;Artificial Sequence> aaccacacauaccagcuggaugucg
<SEQ ID NO. 3132;RNA;Artificial Sequence> guggagcgguccccucaccggccca
<SEQ ID NO. 3133;RNA;Artificial Sequence> auccugcaagcaggguugcccgcca
<SEQ ID NO. 3134;RNA;Artificial Sequence> aacaaaacaguggcccuggguagca
<SEQ ID NO. 3135;RNA;Artificial Sequence> aacguggaguucauguguaaggugu
<SEQ ID NO. 3136;RNA;Artificial Sequence> uacagugacccgcagccgcacaucc
<SEQ ID NO. 3137;RNA;Artificial Sequence> caguggcuaaagcacaucgagguga
<SEQ ID NO. 3138;RNA;Artificial Sequence> aaugggagcaagauuggcccagaca
<SEQ ID NO. 3139;RNA; Artificial Sequence> aaccugccuuauguccagaucuuga
<SEQ ID NO. 3140;RNA;Artificial Sequence> aagacugcuggaguuaauaccaccg
<SEQ ID NO.3141;RNA;Artificial Sequence> gacaaagagauggaggugcuucacu
<SEQ ID NO. 3142;RNA;Artificial Sequence> uuaagaaaugucuccuuugaggacg
<SEQ ID NO. 3143;RNA;Artificial Sequence> gcaggggaguauacgugcuuggcgg
<SEQ ID NO. 3144;RNA;Artificial Sequence> gguaacucuaucggacucucccauc
<SEQ ID NO. 3145;RNA;Artificial Sequence> cacucugcaugguugaccguucugg
<SEQ ID NO. 3146;RNA;Artificial Sequence> gaagcccuggaagagaggccggcag
<SEQ ID NO.3147;RNA;Artificial Sequence> gugaugaccucgccccuguaccugg
<SEQ ID NO. 3148;RNA;Artificial Sequence> gagaucaucaucuauugcacagggg
<SEQ ID NO. 3149;RNA;Artificial Sequence> gccuuccucaucuccugcauggugg
<SEQ ID NO. 3150;RNA;Artificial Sequence> gggucggucaucgucuacaagauga
<SEQ ID NO. 3151;RNA;Artificial Sequence> aagagugguaccaagaagagugacu
<SEQ ID NO. 3152;RNA;Artificial Sequence> uuccacagccagauggcugugcaca
<SEQ ID NO. 3153;RNA;Artificial Sequence> aagcuggccaagagcaucccucugc
<SEQ ID NO. 3154;RNA;Artificial Sequence> cgcagacagguaacagugucugcug
<SEQ ID NO. 3155;RNA;Artificial Sequence> gacuccagugcauccaugaacucug
<SEQ ID NO. 3156;RNA;Artificial Sequence> gggguucuucugguucggccaucac
<SEQ ID NO. 3157;RNA;Artificial Sequence> cggcucuccuccagugggacuccca
<SEQ ID NO. 3158;RNA;Artificial Sequence> augcuagcaggggucucugaguaug
<SEQ ID NO. 3159;RNA;Artificial Sequence> gagcuucccgaagacccucgcuggg
<SEQ ID NO. 3160;RNA;Artificial Sequence> gagcugccucgggacagacuggucu
<SEQ ID NO. 3161;RNA;Artificial Sequence> uuaggcaaaccccugggagagggcu
<SEQ ID NO. 3162;RNA;Artificial Sequence> ugcuuugggcaggugguguuggcag
<SEQ ID NO. 3163;RNA;Artificial Sequence> gaggcuaucgggcuggacaaggaca
<SEQ ID NO. 3164;RNA;Artificial Sequence> aaacccaaccgugugaccaaagugg
<SEQ ID NO. 3165;RNA;Artificial Sequence> gcugugaagauguugaagucggacg
<SEQ ID NO. 3166;RNA;Artificial Sequence> gcaacagagaaagacuugucagacc
<SEQ ID NO. 3167;RNA;Artificial Sequence> cugaucucagaaauggagaugauga
<SEQ ID NO. 3168;RNA;Artificial Sequence> aagaugaucgggaagcauaagaaua
<SEQ ID NO. 3169;RNA;Artificial Sequence> aucaucaaccugcugggggccugca
<SEQ ID NO. 3170;RNA;Artificial Sequence> acgcaggauggucccuuguauguca
<SEQ ID NO. 3171;RNA;Artificial Sequence> aucguggaguaugccuccaagggca
<SEQ ID NO. 3172;RNA;Artificial Sequence> aaccugcgggaguaccugcaggccc
<SEQ ID NO.3173;RNA;Artificial Sequence> cggaggcccccagggcuggaauacu
<SEQ ID NO. 3174;RNA;Artificial Sequence> ugcuacaaccccagccacaacccag
<SEQ ID NO.3175;RNA;Artificial Sequence> gaggagcagcucuccuccaaggacc
<SEQ ID NO. 3176;RNA;Artificial Sequence> cugguguccugcgccuaccaggugg
<SEQ ID NO. 3177;RNA;Artificial Sequence> gcccgaggcauggaguaucuggccu
<SEQ ID NO. 3178;RNA;Artificial Sequence> uccaagaagugcauacaccgagacc
<SEQ ID NO. 3179;RNA;Artificial Sequence> cuggcagccaggaauguccugguga
<SEQ ID NO. 3180;RNA;Artificial Sequence> acagaggacaaugugaugaagauag
<SEQ ID NO. 3181;RNA;Artificial Sequence> gcagacuuuggccucgcacgggaca
<SEQ ID NO. 3182;RNA;Artificial Sequence> auucaccacaucgacuacuauaaaa
<SEQ ID NO. 3183;RNA;Artificial Sequence> aagacaaccaacggccgacugccug
<SEQ ID NO. 3184;RNA;Artificial Sequence> gugaaguggauggcacccgaggcau
741-3719

CA 02677068 2009-09-01
<SEQ ID NO. 3185;RNA;Artificial Sequence> uuauuugaccggaucuacacccacc
<SEQ ID NO. 3186;RNA;Artificial Sequence> cagagugauguguggucuuucgggg
<SEQ ID NO. 3187;RNA;Artificial Sequence> gugcuccugugggagaucuucacuc
<SEQ ID NO. 3188;RNA;Artificial Sequence> cugggcggcuccccauaccccggug
<SEQ ID NO. 3189;RNA;Artificial Sequence> gugccuguggaggaacuuuucaagc
<SEQ ID NO. 3190;RNA;Artificial Sequence> cugcugaaggagggucaccgcaugg
<SEQ ID NO. 3191;RNA;Artificial Sequence> gacaagcccaguaacugcaccaacg
<SEQ ID NO. 3192;RNA;Artificial Sequence> gagcuguacaugaugaugcgggacu
<SEQ ID NO. 3193;RNA;Artificial Sequence> ugcuggcaugcagugcccucacaga
<SEQ ID NO. 3194;RNA;Artificial Sequence> agacccaccuucaagcagcuggugg
<SEQ ID NO. 3195;RNA;Artificial Sequence> gaagaccuggaccgcaucguggccu
<SEQ ID NO. 3196;RNA;Artificial Sequence> uugaccuccaaccaggaguaccugg
<SEQ ID NO. 3197;RNA;Artificial Sequence> gaccuguccaugccccuggaccagu
<SEQ ID NO. 3198;RNA;Artificial Sequence> uacucccccagcuuucccgacaccc
<SEQ ID NO. 3199;RNA;Artificial Sequence> cggagcucuacgugcuccucagggg
<SEQ ID NO. 3200;RNA;Artificial Sequence> gaggauuccgucuucucucaugagc
<SEQ ID NO. 3201;RNA;Artificial Sequence> ccgcugcccgaggageccugccugc
<SEQ ID NO. 3202;RNA;Artificial Sequence> ccccgacacccagcccagcuugcca
<SEQ ID NO. 3203;RNA;Artificial Sequence> aauggcggacucaaacgccgcugac
<SEQ ID NO. 3204;RNA;Artificial Sequence> cugccacccacacgcccuccccaga
<SEQ ID NO. 3205;RNA;Artificial Sequence> acuccaccgucagcuguaacccuca
<SEQ ID NO. 3206;RNA;Artificial Sequence> acccacagccccugcugggcccacc
<SEQ ID NO. 3207;RNA;Artificial Sequence> caccuguccgucccuguccccuuuc
<SEQ ID NO. 3208;RNA;Artificial Sequence> ccugcuggcaggagccggcugccua
<SEQ ID NO. 3209;RNA;Artificial Sequence> accaggggccuuccuguguggccug
<SEQ ID NO. 3210;RNA;Artificial Sequence> gccuucaccccacucagcucaccuc
<SEQ ID NO. 3211;RNA;Artificial Sequence> cucccuccaccuccucuccaccugc
<SEQ ID NO. 3212;RNA;Artificial Sequence> cuggugagaggugcaaagaggcaga
<SEQ ID NO. 3213;RNA;Artificial Sequence> aucuuugcugccagccacuucaucc
<SEQ ID NO. 3214;RNA;Artificial Sequence> cccucccagauguuggaccaacacc
<SEQ ID NO. 3215;RNA;Artificial Sequence> cccucccugccaccaggcacugccu
<SEQ ID NO. 3216;RNA;Artificial Sequence> uggagggcagggagugggagccaau
<SEQ ID NO. 3217;RNA;Artificial Sequence> ugaacaggcaugcaagugagagcuu
<SEQ ID NO. 3218;RNA;Artificial Sequence> uccugagcuuucuccugucgguuug
<SEQ ID NO. 3219;RNA;Artificial Sequence> ggucuguuuugccuucacccauaag
<SEQ ID NO. 3220;RNA;Artificial Sequence> gccccucgcacucugguggcaggug
<SEQ ID NO. 3221;RNA;Artificial Sequence> gccuuguccucagggcuacagcagu
<SEQ ID NO. 3222;RNA;Artificial Sequence> uagggaggucagugcuucgugccuc
<SEQ ID NO. 3223;RNA;Artificial Sequence> cgauugaaggugaccucugccccag
<SEQ ID NO. 3224;RNA;Artificial Sequence> gauagguggugccaguggcuuauua
<SEQ ID NO. 3225;RNA;Artificial Sequence> aauuccgauacuaguuugcuuugcu
<SEQ ID NO. 3226;RNA;Artificial Sequence> ugaccaaaugccugguaccagagga
<SEQ ID NO. 3227;RNA;Artificial Sequence> auggugaggcgaaggccagguuggg
<SEQ ID NO. 3228;RNA;Artificial Sequence> gggcaguguuguggcccuggggccc
<SEQ ID NO. 3229;RNA;Artificial Sequence> cagccccaaacugggggcucuguau
<SEQ ID NO. 3230;RNA;Artificial Sequence> uauagcuaugaagaaaacacaaagu
<SEQ ID NO. 3231;RNA;Artificial Sequence> uguauaaaucugaguauauauuuac
<SEQ ID NO. 3232;RNA;Artificial Sequence> caugucuuuuuaaaagggucguuac
<SEQ ID NO. 3233;RNA;Artificial Sequence> ccagagauuuacccaucggguaaga
<SEQ ID NO. 3234;RNA;Artificial Sequence> augcuccugguggcugggaggcauc
<SEQ ID NO. 3235;RNA;Artificial Sequence> caguugcuauauauuaaaaacaaaa
<SEQ ID NO. 3236;RNA;Artificial Sequence> aaagaaaaaaaaggaaaauguuuuu
<SEQ ID NO. 3237;RNA;Artificial Sequence> uaaaaaggucauauauuuuuugcua
<SEQ ID NO. 3238;RNA;Artificial Sequence> acuuuugcuguuuuauuuuuuuaaa
<SEQ ID NO. 3239;RNA;Artificial Sequence> auuauguucuaaaccuauuuucagu
<SEQ ID NO. 3240;RNA;Artificial Sequence> uuuaggucccucaauaaaaauugcu
<SEQ ID NO. 3241;RNA;Artificial Sequence> ugcugcuucauuuaucuaugggcug
<SEQ ID NO. 3242;RNA;Artificial Sequence> guaugaaaagggugggaauguccac
<SEQ ID NO. 3243;RNA;Artificial Sequence> cuggaaagaagggacacccacgggc
<SEQ ID NO. 3244;RNA;Artificial Sequence> cccuggggcuaggucugucccgagg
<SEQ ID NO. 3245;RNA;Artificial Sequence> ggcaccgcaugcucccggcgcaggu
<SEQ ID NO. 3246;RNA;Artificial Sequence> uuccuuguaaccucuucuuccuagg
<SEQ ID NO. 3247;RNA;Artificial Sequence> guccugcacccagaccucacgacgc
<SEQ ID NO. 3248;RNA;Artificial Sequence> caccuccugccucuccgcugcuuuu
<SEQ ID NO. 3249;RNA;Artificial Sequence> uggaaagucagaaaaagaagauguc
<SEQ ID NO. 3250;RNA;Artificial Sequence> cugcuucgagggcaggaaccccauc
<SEQ ID NO. 3251;RNA;Artificial Sequence> ccaugcaguagaggcgcugggcaga
<SEQ ID NO. 3252;RNA;Artificial Sequence> agagucaaggcccagcagccaucga
<SEQ ID NO. 3253;RNA;Artificial Sequence> accauggaugguuuccuccaaggaa
<SEQ ID NO. 3254;RNA;Artificial Sequence> aaccggugggguugggcuggggagg
<SEQ ID NO. 3255;RNA;Artificial Sequence> ggggcaccuaccuaggaauagccac
<SEQ ID NO. 3256;RNA;Artificial Sequence> cgggguagagcuacagugauuaaga
<SEQ ID NO. 3257;RNA;Artificial Sequence> aggaaagcaagggcgcgguugcuca
741-3720

CA 02677068 2009-09-01
<SEQ ID NO. 3258;RNA;Artificial Sequence> acgccuguaaucccagcacuuuggg
<SEQ ID NO. 3259;RNA;Artificial Sequence> gacaccgaggugggcagaucacuuc
<SEQ ID NO. 3260;RNA;Artificial Sequence> caggucaggaguuugagaccagccu
<SEQ ID NO. 3261;RNA;Artificial Sequence> uggccaacuuagugaaaccccaucu
<SEQ ID NO. 3262;RNA;Artificial Sequence> ucuacuaaaaaugcaaaaauuaucc
<SEQ ID NO. 3263;RNA;Artificial Sequence> caggcaugguggcacacgccuguaa
<SEQ ID NO. 3264;RNA;Artificial Sequence> aucccagcuccacaggaggcugagg
<SEQ ID NO. 3265;RNA;Artificial Sequence> gcagaaucccuugaagcugggaggc
<SEQ ID NO. 3266;RNA;Artificial Sequence> cggagguugcagugagccgagauug
<SEQ ID NO. 3267;RNA;Artificial Sequence> gcgccauugcacuccagccugggca
<SEQ ID NO. 3268;RNA;Artificial Sequence> aacagagaaaacaaaaaggaaaaca
<SEQ ID NO. 3269;RNA;Artificial Sequence> aaaugaugaaggucugcagaaacug
<SEQ ID NO. 3270;RNA;Artificial Sequence> gaaacccagacaugugucugccccc
<SEQ ID NO. 3271;RNA;Artificial Sequence> cucuaugugggcaugguuuugccag
<SEQ ID NO. 3272;RNA;Artificial Sequence> gugcuucuaagugcaggagaacaug
<SEQ ID NO. 3273;RNA;Artificial Sequence> gucaccugaggcuaguuuugcauuc
<SEQ ID NO. 3274;RNA;Artificial Sequence> caggucccuggcuucguuucuuguu
<SEQ ID NO. 3275;RNA;Artificial Sequence> ugguaugccuccccagaucguccuu
<SEQ ID NO. 3276;RNA;Artificial Sequence> uccuguauccaugugaccagacugu
<SEQ ID NO. 3277;RNA;Artificial Sequence> uauuuguugggacugucgcagaucu
<SEQ ID NO. 3 278;RNA; Artificial Sequence> uuggcuucuuacaguucuuccuguc
<SEQ ID NO. 3279;RNA;Artificial Sequence> ccaaacuccauccugucccucagga
<SEQ ID NO. 3280;RNA;Artificial Sequence> aacggggggaaaauucuccgaaugu
<SEQ ID NO. 3281;RNA;Artificial Sequence> uuuuugguuuuuuggcugcuuggaa
<SEQ ID NO. 3282;RNA;Artificial Sequence> auuuacuucugccaccugcugguca
<SEQ ID NO. 3283;RNA;Artificial Sequence> aucacuguccucacuaaguggauuc
<SEQ ID NO. 3284;RNA;Artificial Sequence> cuggcucccccguaccucauggcuc
<SEQ ID NO. 3285;RNA;Artificial Sequence> caaacuaccacuccucagucgcuau
<SEQ ID NO. 3286;RNA;Artificial Sequence> uauuaaagcuuauauuuugcuggau
<SEQ ID NO. 3287;RNA; Artificial Sequence> uuacugcuaaauacaaaagaaaguu
<SEQ ID NO. 3288;RNA;Artificial Sequence> ucaauauguuuucauuucuguaggg
<SEQ ID NO. 3289;RNA;Artificial Sequence> gaaaaugggauugcugcuuuaaauu
<SEQ ID NO.3290;RNA;Artificial Sequence> uucugagcuagggauuuuuuggcag
<SEQ ID NO. 3291;RNA;Artificial Sequence> gcugcaguguuggcgacuauuguaa
<SEQ ID NO. 3292;RNA;Artificial Sequence> aaauucucuuuguuucucucuguaa
<SEQ ID NO. 3293;RNA;Artificial Sequence> aauagcaccugcuaacauuacaauu
<SEQ ID NO. 3294;RNA;Artificial Sequence> uuguauuuauguuuaaagaaggcau
<SEQ ID NO. 3295;RNA;Artificial Sequence> ucauuuggugaacagaacuaggaaa
<SEQ ID NO. 3296;RNA;Artificial Sequence> augaauuuuuagcucuuaaaagcau
<SEQ ID NO. 3297;RNA;Artificial Sequence> uuugcuuugagaccgcacaggagug
<SEQ ID NO. 3298;RNA;Artificial Sequence> gucuuuccuuguaaaacagugauga
<SEQ ID NO. 3299;RNA;Artificial Sequence> auaauuucugccuuggcccuaccuu
<SEQ ID NO. 3300;RNA;Artificial Sequence> ugaagcaauguugugugaagggaug
<SEQ ID NO. 3301;RNA;Artificial Sequence> gaagaaucuaaaagucuucauaagu
<SEQ ID NO. 3302;RNA;Artificial Sequence> uccuugggagaggugcuagaaaaau
<SEQ ID NO. 3303;RNA;Artificial Sequence> uauaaggcacuaucauaauuacagu
<SEQ ID NO. 3304;RNA;Artificial Sequence> ugauguccuugcuguuacuacucaa
<SEQ ID NO. 3305;RNA;Artificial Sequence> aaucacccacaaauuuccccaaaga
<SEQ ID NO. 3306;RNA;Artificial Sequence> acugcgcuagcugucaaauaaaaga
<SEQ ID NO.3307;RNA;Artificial Sequence> acagugaaauugaccugaaaaaaaa
<SEQ ID NO. 3308;RNA;Artificial Sequence> ccuuauguccagaucuugaagguaa
<SEQ ID NO. 3309;RNA;Artificial Sequence> aucauggcaccagucuucgugggcc
<SEQ ID NO. 3310;RNA;Artificial Sequence> cagucuacugggaaggagaccacug
<SEQ ID NO. 3311;RNA;Artificial Sequence> gucucgggggcucaaguuccugugg
<SEQ ID NO. 3312;RNA;Artificial Sequence> ggcaggcucaguugcccccgaaugg
<SEQ ID NO.3313;RNA;Artificial Sequence> ggaucauuccucacgcuucaggcac
<SEQ ID NO. 3314;RNA;Artificial Sequence> cacacacuccaucucaguagggauc
<SEQ ID NO. 3315;RNA;Artificial Sequence> cuagccacaucccccaggacuagua
<SEQ ID NO. 3316;RNA;Artificial Sequence> aacagaggucacaaaguggagguga
<SEQ ID NO. 3317;RNA;Artificial Sequence> agcugggaacagagggcugcaggga
<SEQ ID NO. 3318;RNA;Artificial Sequence> auggguggugcuggucuguaauaag
<SEQ ID NO. 3319;RNA;Artificial Sequence> gcuuugagagcaacgucacuggggc
<SEQ ID NO. 3320;RNA;Artificial Sequence> cuuuggggucagcuacacaaggaag
<SEQ ID NO. 3321;RNA;Artificial Sequence> ggcauuuggaccccugccuuuucau
<SEQ ID NO. 3322;RNA;Artificial Sequence> uugcccgaaaccagagccuuuccac
<SEQ ID NO. 3323;RNA;Artificial Sequence> ccaagcguuucccagucuuagcccu
<SEQ ID NO. 3324;RNA; Artificial Sequence> uguguccugaguuacguacgaucuu
<SEQ ID NO. 3 325;RNA; Artificial Sequence> uucuggcaaauggggugcaugauaa
<SEQ ID NO. 3326;RNA;Artificial Sequence> agagcaucucuuacgaagaguugga
<SEQ ID NO. 3327;RNA;Artificial Sequence> aaaaacaaaugccauauauaaauuc
<SEQ ID NO. 3328;RNA;Artificial Sequence> cuaagccauaugaggacgaggagua
<SEQ ID NO. 3329;RNA;Artificial Sequence> aauggcauuuucuuccuuuuuccuc
<SEQ ID NO. 3330;RNA;Artificial Sequence> cucacucccagacauucauuguccc
741-3721

CA 02677068 2009-09-01
<SEQ ID NO. 3331;RNA;Artificial Sequence> cugaaugcuccauuaauccagggaa
<SEQ ID NO. 3332;RNA;Artificial Sequence> agguaauugccuaaaucuccagugg
<SEQ ID NO. 3333;RNA;Artificial Sequence> gaucucgcaacaggaaggaaccaga
<SEQ ID NO. 3334;RNA;Artificial Sequence> aagcugggaaaguuguuuaccucuu
<SEQ ID NO. 3335;RNA;Artificial Sequence> uugucccagaguuagaccucauccu
<SEQ ID NO. 3336;RNA;Artificial Sequence> uccccuagcuuagcugucucagaga
<SEQ ID NO. 3337;RNA;Artificial Sequence> auauacuggcccucccuucucuucu
<SEQ ID NO. 3338;RNA;Artificial Sequence> ucuuugcugcuggugcuaaaacugc
<SEQ ID NO. 3339;RNA;Artificial Sequence> cucuguaggucauuggccacugucu
<SEQ ID NO. 3340;RNA;Artificial Sequence> uccacucacaaccccugcuccaguc
<SEQ ID NO. 3341;RNA;Artificial Sequence> ccuggagggaguggguuaaacacaa
<SEQ ID NO. 3342;RNA;Artificial Sequence> aauagaacauuccauuugaagcagu
<SEQ ID NO. 3343;RNA;Artificial Sequence> uuuaaucaaaugcuuuggacuuuug
<SEQ ID NO. 3344;RNA;Artificial Sequence> gaaguccacuuguucuguacuugua
<SEQ ID NO. 3345;RNA;Artificial Sequence> aaaagggaaagaaggccgggcgcag
<SEQ ID NO. 3346;RNA;Artificial Sequence> guggcucacgccuguaaucccagca
<SEQ ID NO. 3347;RNA;Artificial Sequence> acuuuagaucacuugaggucaggag
<SEQ ID NO. 3348;RNA;Artificial Sequence> guuugagaccagcccggccaacaug
<SEQ ID NO. 3349;RNA;Artificial Sequence> ggugaaaccccaucucuacuaaaaa
<SEQ ID NO. 3350;RNA;Artificial Sequence> auacaaaaauuagcugugcauagug
<SEQ ID NO. 3351;RNA;Artificial Sequence> gguuggcaccuguagucccagcuac
<SEQ ID NO. 3352;RNA;Artificial Sequence> cucaggaggcugaggcaagcuaacu
<SEQ ID NO. 3353;RNA;Artificial Sequence> ugcuugaacccagaaggcagagguu
<SEQ ID NO. 3354;RNA;Artificial Sequence> ugcagugagcugagaucacgccacu
<SEQ ID NO. 3355;RNA;Artificial Sequence> ugcacuccagccugggugacagagu
<SEQ ID NO. 3356;RNA;Artificial Sequence> ugagugagacucugcguuaaaaaaa
<SEQ ID NO. 3357;RNA;Artificial Sequence> aagguaaucauggcaccagucuucg
<SEQ ID NO. 3358;RNA;Artificial Sequence> gugggccagucuacugggaaggaga
<SEQ ID NO. 3359;RNA;Artificial Sequence> accacugucucgggggcucaaguuc
<SEQ ID NO. 3360;RNA;Artificial Sequence> ccugugggcaggcucaguugccccc
<SEQ ID NO. 3361;RNA;Artificial Sequence> cgaaugggaucauuccucacgcuuc
<SEQ ID NO. 3362;RNA;Artificial Sequence> caggcacacacacuccaucucagua
<SEQ ID NO. 3363;RNA;Artificial Sequence> agggaucuagccacaucccccagga
<SEQ ID NO. 3364;RNA;Artificial Sequence> acuaguaacagaggucacaaagugg
<SEQ ID NO. 3365;RNA;Artificial Sequence> gaggugagcugggaacagagggcug
<SEQ ID NO. 3366;RNA;Artificial Sequence> gcagggauggguggugcuggucugu
<SEQ ID NO. 3367;RNA;Artificial Sequence> uaauaagcuuugagagcaacgucac
<SEQ ID NO. 3368;RNA;Artificial Sequence> cuggggcuuuggggucagcuacaca
<SEQ ID NO. 3369;RNA;Artificial Sequence> aaggaaggcauuuggaccccugccu
<SEQ ID NO. 3370;RNA;Artificial Sequence> uuuucauugcccgaaaccagagccu
<SEQ ID NO. 3371;RNA;Artificial Sequence> uuuccaccaagcguuucccagucuu
<SEQ ID NO. 3372;RNA;Artificial Sequence> uagcccuguguccugaguuacguac
<SEQ ID NO. 3373;RNA;Artificial Sequence> cgaucuuucuggcaaauggggugca
<SEQ ID NO. 3374;RNA;Artificial Sequence> augauaagagcaucucuuacgaaga
<SEQ ID NO. 3375;RNA;Artificial Sequence> aguuggaaaaacaaaugccauauau
<SEQ ID NO. 3376;RNA;Artificial Sequence> uaaauucuaagccauaugaggacga
<SEQ ID NO. 3377;RNA;Artificial Sequence> aggaguaauggcauuuucuuccuuu
<SEQ ID NO. 3378;RNA;Artificial Sequence> uuuccucucacucccagacauucau
<SEQ ID NO. 3379;RNA;Artificial Sequence> uugucccugaaugcuccauuaaucc
<SEQ ID NO. 3380;RNA;Artificial Sequence> cagggaagguaauugccuaaaucuc
<SEQ ID NO. 3381;RNA;Artificial Sequence> ccaguggaucucgcaacaggaagga
<SEQ ID NO. 3382;RNA;Artificial Sequence> aaccagaagcugggaaaguuguuua
<SEQ ID NO. 3383;RNA;Artificial Sequence> accucuuugucccagaguuagaccu
<SEQ ID NO. 3384;RNA;Artificial Sequence> ucauccuccccuagcuuagcugucu
<SEQ ID NO. 3385;RNA;Artificial Sequence> ucagagauauacuggcccucccuuc
<SEQ ID NO.3386;RNA;Artificial Sequence> cucuucucuuugcugcuggugcuaa
<SEQ ID NO. 3387;RNA;Artificial Sequence> aaacugcucuguaggucauuggcca
<SEQ ID NO. 3388;RNA;Artificial Sequence> acugucuccacucacaaccccugcu
<SEQ ID NO. 3389;RNA;Artificial Sequence> uccaguccuggagggaguggguuaa
<SEQ ID NO. 3390;RNA;Artificial Sequence> aacacaaauagaacauuccauuuga
<SEQ ID NO. 3391;RNA;Artificial Sequence> uuuuuuuuuaaucaaaugcuuugga
<SEQ ID NO. 3392;RNA;Artificial Sequence> acuuuugaaguccacuuguucugua
<SEQ ID NO. 3393;RNA;Artificial Sequence> acuuguaaaagggaaagaaggccgg
<SEQ ID NO. 3394;RNA;Artificial Sequence> ggcgcaguggcucacgccuguaauc
<SEQ ID NO.3395;RNA;Artificial Sequence> cccagcacuuuagaucacuugaggu
<SEQ ID NO. 3396;RNA;Artificial Sequence> ucaggaguuugagaccagcccggcc
<SEQ ID NO. 3397;RNA;Artificial Sequence> caacauggugaaaccccaucucuac
<SEQ ID NO. 3398;RNA;Artificial Sequence> cuaaaaauacaaaaauuagcugugc
<SEQ ID NO. 3399;RNA;Artificial Sequence> cauagugguuggcaccuguaguccc
<SEQ ID NO. 3400;RNA;Artificial Sequence> cagcuacucaggaggcugaggcaag
<SEQ ID NO. 3401;RNA;Artificial Sequence> gcuaacugcuugaacccagaaggca
<SEQ ID NO. 3402;RNA;Artificial Sequence> agagguugcagugagcugagaucac
<SEQ ID NO. 3403;RNA;Artificial Sequence> cgccacugcacuccagccuggguga
741-3722

CA 02677068 2009-09-01
<SEQ ID NO. 3404;RNA;Artificial Sequence> acagagugagugagacucugcguua
<SEQ ID NO. 3405;RNA;Homo sapiens>
GGCGGCGGCUGGAGGAGAGCGCGGUGGAGAGCCGAGCGGGCGGGCGGCGGGUGCGGAGCGGGCGAGGGAG
CGCGCGCGGCCGCCACAAAGCUCGGGCGCCGCGGGGCUGCAUGCGGCGUACCUGGCCCGGCGCGGCGACUGCUCUCCG
GGCUGGCGGGGGCCGGCCGCGAGCCCCGGGGGCCCCGAGGCCGCAGCUUGCCUGCGCGCUCUGAGCCUUCGCAACUCG
CGAGCAAAGUUUGGUGGAGGCAACGCCAAGCCUGAGUCCUUUCUUCCUCUCGUUCCCCAAAUCCGAGGGCAGCCCGC
GGGCGUCAUGCCCGCGCUCCUCCGCAGCCUGGGGUACGCGUGAAGCCCGGGAGGCUUGGCGCCGGCGAAGACCCAAG
GACCACUCUUCUGCGUUUGGAGUUGCUCCCCGCAACCCCGGGCUCGUCGCUUUCUCCAUCCCGACCCACGCGGGGCGC
GGGGACAACACAGGUCGCGGAGGAGCGUUGCCAUUCAAGUGACUGCAGCAGCAGCGGCAGCGCCUCGGUUCCUGAGC
CCACCGCAGGCUGAAGGCAUUGCGCGUAGUCCAUGCCCGUAGAGGAAGUGUGCAGAUGGGAUUAACGUCCACAUGGA
GAUAUGGAAGAGGACCGGGGAUUGGUACCGUAACCAUGGUCAGCUGGGGUCGUUUCAUCUGCCUGGUCGUGGUCAC
CAUGGCAACCUUGUCCCUGGCCCGGCCCUCCUUCAGUUUAGUUGAGGAUACCACAUUAGAGCCAGAAGAGCCACCAA
CCAAAUACCAAAUCUCUCAACCAGAAGUGUACGUGGCUGCGCCAGGGGAGUCGCUAGAGGUGCGCUGCCUGUUGAAA
GAUGCCGCCGUGAUCAGUUGGACUAAGGAUGGGGUGCACUUGGGGCCCAACAAUAGGACAGUGCUUAUUGGGGAGU
ACUUGCAGAUAAAGGGCGCCACGCCUAGAGACUCCGGCCUCUAUGCUUGUACUGCCAGUAGGACUGUAGACAGUGAA
ACUUGGUACUUCAUGGUGAAUGUCACAGAUGCCAUCUCAUCCGGAGAUGAUGAGGAUGACACCGAUGGUGCGGAAG
AUUUUGUCAGUGAGAACAGUAACAACAAGAGAGCACCAUACUGGACCAACACAGAAAAGAUGGAAAAGCGGCUCCA
UGCUGUGCCUGCGGCCAACACUGUCAAGUUUCGCUGCCCAGCCGGGGGGAACCCAAUGCCAACCAUGCGGUGGCUGA
AAAACGGGAAGGAGUUUAAGCAGGAGCAUCGCAUUGGAGGCUACAAGGUACGAAACCAGCACUGGAGCCUCAUUAU
GGAAAGUGUGGUCCCAUCUGACAAGGGAAAUUAUACCUGUGUAGUGGAGAAUGAAUACGGGUCCAUCAAUCACACG
UACCACCUGGAUGUUGUGGAGCGAUCGCCUCACCGGCCCAUCCUCCAAGCCGGACUGCCGGCAAAUGCCUCCACAGU
GGUCGGAGGAGACGUAGAGUUUGUCUGCAAGGUUUACAGUGAUGCCCAGCCCCACAUCCAGUGGAUCAAGCACGUGG
AAAAGAACGGCAGUAAAUACGGGCCCGACGGGCUGCCCUACCUCAAGGUUCUCAAGCACUCGGGGAUAAAUAGUUCC
AAUGCAGAAGUGCUGGCUCUGUUCAAUGUGACCGAGGCGGAUGCUGGGGAAUAUAUAUGUAAGGUCUCCAAUUAUA
UAGGGCAGGCCAACCAGUCUGCCUGGCUCACUGUCCUGCCAAAACAGCAAGCGCCUGGAAGAGAAAAGGAGAUUACA
GCUUCCCCAGACUACCUGGAGAUAGCCAUUUACUGCAUAGGGGUCUUCUUAAUCGCCUGUAUGGUGGUAACAGUCAU
CCUGUGCCGAAUGAAGAACACGACCAAGAAGCCAGACUUCAGCAGCCAGCCGGCUGUGCACAAGCUGACCAAACGUA
UCCCCCUGCGGAGACAGGUAACAGUUUCGGCUGAGUCCAGCUCCUCCAUGAACUCCAACACCCCGCUGGUGAGGAUA
ACAACACGCCUCUCUUCAACGGCAGACACCCCCAUGCUGGCAGGGGUCUCCGAGUAUGAACUUCCAGAGGACCCAAA
AUGGGAGUUUCCAAGAGAUAAGCUGACACUGGGCAAGCCCCUGGGAGAAGGUUGCUUUGGGCAAGUGGUCAUGGCG
GAAGCAGUGGGAAUUGACAAAGACAAGCCCAAGGAGGCGGUCACCGUGGCCGUGAAGAUGUUGAAAGAUGAUGCCA
CAGAGAAAGACCUUUCUGAUCUGGUGUCAGAGAUGGAGAUGAUGAAGAUGAUUGGGAAACACAAGAAUAUCAUAAA
UCUUCUUGGAGCCUGCACACAGGAUGGGCCUCUCUAUGUCAUAGUUGAGUAUGCCUCUAAAGGCAACCUCCGAGAAU
ACCUCCGAGCCCGGAGGCCACCCGGGAUGGAGUACUCCUAUGACAUUAACCGUGUUCCUGAGGAGCAGAUGACCUUC
AAGGACUUGGUGUCAUGCACCUACCAGCUGGCCAGAGGCAUGGAGUACUUGGCUUCCCAAAAAUGUAUUCAUCGAGA
UUUAGCAGCCAGAAAUGUUUUGGUAACAGAAAACAAUGUGAUGAAAAUAGCAGACUUUGGACUCGCCAGAGAUAUC
AACAAUAUAGACUAUUACAAAAAGACCACCAAUGGGCGGCUUCCAGUCAAGUGGAUGGCUCCAGAAGCCCUGUUUGA
UAGAGUAUACACUCAUCAGAGUGAUGUCUGGUCCUUCGGGGUGUUAAUGUGGGAGAUCUUCACUUUAGGGGGCUCG
CCCUACCCAGGGAUUCCCGUGGAGGAACUUUUUAAGCUGCUGAAGGAAGGACACAGAAUGGAUAAGCCAGCCAACUG
CACCAACGAACUGUACAUGAUGAUGAGGGACUGUUGGCAUGCAGUGCCCUCCCAGAGACCAACGUUCAAGCAGUUGG
UAGAAGACUUGGAUCGAAUUCUCACUCUCACAACCAAUGAGGAAUACUUGGACCUCAGCCAACCUCUCGAACAGUAU
UCACCUAGUUACCCUGACACAAGAAGUUCUUGUUCUUCAGGAGAUGAUUCUGUUUUUUCUCCAGACCCCAUGCCUUA
CGAACCAUGCCUUCCUCAGUAUCCACACAUAAACGGCAGUGUUAAAACAUGAAUGACUGUGUCUGCCUGUCCCCAAA
CAGGACAGCACUGGGAACCUAGCUACACUGAGCAGGGAGACCAUGCCUCCCAGAGCUUGUUGUCUCCACUUGUAUAU
AUGGAUCAGAGGAGUAAAUAAUUGGAAAAGUAAUCAGCAUAUGUGUAAAGAUUUAUACAGUUGAAAACUUGUAAUC
UUCCCCAGGAGGAGAAGAAGGUUUCUGGAGCAGUGGACUGCCACAAGCCACCAUGUAACCCCUCUCACCUGCCGUGC
GUACUGGCUGUGGACCAGUAGGACUCAAGGUGGACGUGCGUUCUGCCUUCCUUGUUAAUUUUGUAAUAAUUGGAGA
AGAUUUAUGUCAGCACACACUUACAGAGCACAAAUGCAGUAUAUAGGUGCUGGAUGUAUGUAAAUAUAUUCAAAUU
AUGUAUAAAUAUAUAUUAUAUAUUUACAAGGAGUUAUUUUUUGUAUUGAUUUUAAAUGGAUGUCCCAAUGCACCUA
GAAAAUUGGUCUCUCUUUUUUUAAUAGCUAUUUGCUAAAUGCUGUUCUUACACAUAAUUUCUUAAUUUUCACCGAG
CAGAGGUGGAAAAAUACUUUUGCUUUCAGGGAAAAUGGUAUAACGUUAAUUUAUUAAUAAAUUGGUAAUAUACAAA
ACAAUUAAUCAUUUAUAGUUUUUUUUGUAAUUUAAGUGGCAUUUCUAUGCAGGCAGCACAGCAGACUAGUUAAUCU
AUUGCUUGGACUUAACUAGUUAUCAGAUCCUUUGAAAAGAGAAUAUUUACAAUAUAUGACUAAUUUGGGGAAAAUG
AAGUUUUGAUUUAUUUGUGUUUAAAUGCUGCUGUCAGACGAUUGUUCUUAGACCUCCUAAAUGCCCCAUAUUAAAA
GAACUCAUUCAUAGGAAGGUGUUUCAUUUUGGUGUGCAACCCUGUCAUUACGUCAACGCAACGUCUAACUGGACUUC
CCAAGAUAAAUGGUACCAGCGUCCUCUUAAAAGAUGCCUUAAUCCAUUCCUUGAGGACAGACCUUAGUUGAAAUGA
UAGCAGAAUGUGCUUCUCUCUGGCAGCUGGCCUUCUGCUUCUGAGUUGCACAUUAAUCAGAUUAGCCUGUAUUCUCU
UCAGUGAAUUUUGAUAAUGGCUUCCAGACUCUUUGGCGUUGGAGACGCCUGUUAGGAUCUUCAAGUCCCAUCAUAG
AAAAUUGAAACACAGAGUUGUUCUGCUGAUAGUUUUGGGGAUACGUCCAUCUUUUUAAGGGAUUGCUUUCAUCUAA
UUCUGGCAGGACCUCACCAAAAGAUCCAGCCUCAUACCUACAUCAGACAAAAUAUCGCCGUUGUUCCUUCUGUACUA
AAGUAUUGUGUUUUGCUUUGGAAACACCCACUCACUUUGCAAUAGCCGUGCAAGAUGAAUGCAGAUUACACUGAUC
UUAUGUGUUACAAAAUUGGAGAAAGUAUUUAAUAAAACCUGUUAAUUUUUAUACUGACAAUAAAAAUGUUUCUACA
GAUAUUAAUGUUAACAAGACAAAAUAAAUGUCACGCAACUUAAAAAAAAAAAAAAAA
<SEQ ID NO. 3406;RNA;Homo sapiens>
GGCGGCGGCUGGAGGAGAGCGCGGUGGAGAGCCGAGCGGGCGGGCGGCGGGUGCGGAGCGGGCGAGGGAG
CGCGCGCGGCCGCCACAAAGCUCGGGCGCCGCGGGGCUGCAUGCGGCGUACCUGGCCCGGCGCGGCGACUGCUCUCCG
GGCUGGCGGGGGCCGGCCGCGAGCCCCGGGGGCCCCGAGGCCGCAGCUUGCCUGCGCGCUCUGAGCCUUCGCAACUCG
CGAGCAAAGUUUGGUGGAGGCAACGCCAAGCCUGAGUCCUUUCUUCCUCUCGUUCCCCAAAUCCGAGGGCAGCCCGC
GGGCGUCAUGCCCGCGCUCCUCCGCAGCCUGGGGUACGCGUGAAGCCCGGGAGGCUUGGCGCCGGCGAAGACCCAAG
GACCACUCUUCUGCGUUUGGAGUUGCUCCCCGCAACCCCGGGCUCGUCGCUUUCUCCAUCCCGACCCACGCGGGGCGC
GGGGACAACACAGGUCGCGGAGGAGCGUUGCCAUUCAAGUGACUGCAGCAGCAGCGGCAGCGCCUCGGUUCCUGAGC
CCACCGCAGGCUGAAGGCAUUGCGCGUAGUCCAUGCCCGUAGAGGAAGUGUGCAGAUGGGAUUAACGUCCACAUGGA
GAUAUGGAAGAGGACCGGGGAUUGGUACCGUAACCAUGGUCAGCUGGGGUCGUUUCAUCUGCCUGGUCGUGGUCAC
741-3723

CA 02677068 2009-09-01
CAUGGCAACCUUGUCCCUGGCCCGGCCCUCCUUCAGUUUAGUUGAGGAUACCACAUUAGAGCCAGAAGAGCCACCAA
CCAAAUACCAAAUCUCUCAACCAGAAGUGUACGUGGCUGCGCCAGGGGAGUCGCUAGAGGUGCGCUGCCUGUUGAAA
GAUGCCGCCGUGAUCAGUUGGACUAAGGAUGGGGUGCACUUGGGGCCCAACAAUAGGACAGUGCUUAUUGGGGAGU
ACUUGCAGAUAAAGGGCGCCACGCCUAGAGACUCCGGCCUCUAUGCUUGUACUGCCAGUAGGACUGUAGACAGUGAA
ACUUGGUACUUCAUGGUGAAUGUCACAGAUGCCAUCUCAUCCGGAGAUGAUGAGGAUGACACCGAUGGUGCGGAAG
AUUUUGUCAGUGAGAACAGUAACAACAAGAGAGCACCAUACUGGACCAACACAGAAAAGAUGGAAAAGCGGCUCCA
UGCUGUGCCUGCGGCCAACACUGUCAAGUUUCGCUGCCCAGCCGGGGGGAACCCAAUGCCAACCAUGCGGUGGCUGA
AAAACGGGAAGGAGUUUAAGCAGGAGCAUCGCAUUGGAGGCUACAAGGUACGAAACCAGCACUGGAGCCUCAUUAU
GGAAAGUGUGGUCCCAUCUGACAAGGGAAAUUAUACCUGUGUAGUGGAGAAUGAAUACGGGUCCAUCAAUCACACG
UACCACCUGGAUGUUGUGGAGCGAUCGCCUCACCGGCCCAUCCUCCAAGCCGGACUGCCGGCAAAUGCCUCCACAGU
GGUCGGAGGAGACGUAGAGUUUGUCUGCAAGGUUUACAGUGAUGCCCAGCCCCACAUCCAGUGGAUCAAGCACGUGG
AAAAGAACGGCAGUAAAUACGGGCCCGACGGGCUGCCCUACCUCAAGGUUCUCAAGGCCGCCGGUGUUAACACCACG
GACAAAGAGAUUGAGGUUCUCUAUAUUCGGAAUGUAACUUUUGAGGACGCUGGGGAAUAUACGUGCUUGGCGGGUA
AUUCUAUUGGGAUAUCCUUUCACUCUGCAUGGUUGACAGUUCUGCCAGCGCCUGGAAGAGAAAAGGAGAUUACAGC
UUCCCCAGACUACCUGGAGAUAGCCAUUUACUGCAUAGGGGUCUUCUUAAUCGCCUGUAUGGUGGUAACAGUCAUCC
UGUGCCGAAUGAAGAACACGACCAAGAAGCCAGACUUCAGCAGCCAGCCGGCUGUGCACAAGCUGACCAAACGUAUC
CCCCUGCGGAGACAGGUAACAGUUUCGGCUGAGUCCAGCUCCUCCAUGAACUCCAACACCCCGCUGGUGAGGAUAAC
AACACGCCUCUCUUCAACGGCAGACACCCCCAUGCUGGCAGGGGUCUCCGAGUAUGAACUUCCAGAGGACCCAAAAU
GGGAGUUUCCAAGAGAUAAGCUGACACUGGGCAAGCCCCUGGGAGAAGGUUGCUUUGGGCAAGUGGUCAUGGCGGA
AGCAGUGGGAAUUGACAAAGACAAGCCCAAGGAGGCGGUCACCGUGGCCGUGAAGAUGUUGAAAGAUGAUGCCACA
GAGAAAGACCUUUCUGAUCUGGUGUCAGAGAUGGAGAUGAUGAAGAUGAUUGGGAAACACAAGAAUAUCAUAAAUC
UUCUUGGAGCCUGCACACAGGAUGGGCCUCUCUAUGUCAUAGUUGAGUAUGCCUCUAAAGGCAACCUCCGAGAAUAC
CUCCGAGCCCGGAGGCCACCCGGGAUGGAGUACUCCUAUGACAUUAACCGUGUUCCUGAGGAGCAGAUGACCUUCAA
GGACUUGGUGUCAUGCACCUACCAGCUGGCCAGAGGCAUGGAGUACUUGGCUUCCCAAAAAUGUAUUCAUCGAGAUU
UAGCAGCCAGAAAUGUUUUGGUAACAGAAAACAAUGUGAUGAAAAUAGCAGACUUUGGACUCGCCAGAGAUAUCAA
CAAUAUAGACUAUUACAAAAAGACCACCAAUGGGCGGCUUCCAGUCAAGUGGAUGGCUCCAGAAGCCCUGUUUGAUA
GAGUAUACACUCAUCAGAGUGAUGUCUGGUCCUUCGGGGUGUUAAUGUGGGAGAUCUUCACUUUAGGGGGCUCGCC
CUACCCAGGGAUUCCCGUGGAGGAACUUUUUAAGCUGCUGAAGGAAGGACACAGAAUGGAUAAGCCAGCCAACUGCA
CCAACGAACUGUACAUGAUGAUGAGGGACUGUUGGCAUGCAGUGCCCUCCCAGAGACCAACGUUCAAGCAGUUGGUA
GAAGACUUGGAUCGAAUUCUCACUCUCACAACCAAUGAGGAAUACUUGGACCUCAGCCAACCUCUCGAACAGUAUUC
ACCUAGUUACCCUGACACAAGAAGUUCUUGUUCUUCAGGAGAUGAUUCUGUUUUUUCUCCAGACCCCAUGCCUUACG
AACCAUGCCUUCCUCAGUAUCCACACAUAAACGGCAGUGUUAAAACAUGAAUGACUGUGUCUGCCUGUCCCCAAACA
GGACAGCACUGGGAACCUAGCUACACUGAGCAGGGAGACCAUGCCUCCCAGAGCUUGUUGUCUCCACUUGUAUAUAU
GGAUCAGAGGAGUAAAUAAUUGGAAAAGUAAUCAGCAUAUGUGUAAAGAUUUAUACAGUUGAAAACUUGUAAUCUU
CCCCAGGAGGAGAAGAAGGUUUCUGGAGCAGUGGACUGCCACAAGCCACCAUGUAACCCCUCUCACCUGCCGUGCGU
ACUGGCUGUGGACCAGUAGGACUCAAGGUGGACGUGCGUUCUGCCUUCCUUGUUAAUUUUGUAAUAAUUGGAGAAG
AUUUAUGUCAGCACACACUUACAGAGCACAAAUGCAGUAUAUAGGUGCUGGAUGUAUGUAAAUAUAUUCAAAUUAU
GUAUAAAUAUAUAUUAUAUAUUUACAAGGAGUUAUUUUUUGUAUUGAUUUUAAAUGGAUGUCCCAAUGCACCUAGA
AAAUUGGUCUCUCUUUUUUUAAUAGCUAUUUGCUAAAUGCUGUUCUUACACAUAAUUUCUUAAUUUUCACCGAGCA
GAGGUGGAAAAAUACUUUUGCUUUCAGGGAAAAUGGUAUAACGUUAAUUUAUUAAUAAAUUGGUAAUAUACAAAAC
AAUUAAUCAUUUAUAGUUUUUUUUGUAAUUUAAGUGGCAUUUCUAUGCAGGCAGCACAGCAGACUAGUUAAUCUAU
UGCUUGGACUUAACUAGUUAUCAGAUCCUUUGAAAAGAGAAUAUUUACAAUAUAUGACUAAUUUGGGGAAAAUGAA
GUUUUGAUUUAUUUGUGUUUAAAUGCUGCUGUCAGACGAUUGUUCUUAGACCUCCUAAAUGCCCCAUAUUAAAAGA
ACUCAUUCAUAGGAAGGUGUUUCAUUUUGGUGUGCAACCCUGUCAUUACGUCAACGCAACGUCUAACUGGACUUCCC
AAGAUAAAUGGUACCAGCGUCCUCUUAAAAGAUGCCUUAAUCCAUUCCUUGAGGACAGACCUUAGUUGAAAUGAUA
GCAGAAUGUGCUUCUCUCUGGCAGCUGGCCUUCUGCUUCUGAGUUGCACAUUAAUCAGAUUAGCCUGUAUUCUCUUC
AGUGAAUUUUGAUAAUGGCUUCCAGACUCUUUGGCGUUGGAGACGCCUGUUAGGAUCUUCAAGUCCCAUCAUAGAA
AAUUGAAACACAGAGUUGUUCUGCUGAUAGUUUUGGGGAUACGUCCAUCUUUUUAAGGGAUUGCUUUCAUCUAAUU
CUGGCAGGACCUCACCAAAAGAUCCAGCCUCAUACCUACAUCAGACAAAAUAUCGCCGUUGUUCCUUCUGUACUAAA
GUAUUGUGUUUUGCUUUGGAAACACCCACUCACUUUGCAAUAGCCGUGCAAGAUGAAUGCAGAUUACACUGAUCUU
AUGUGUUACAAAAUUGGAGAAAGUAUUUAAUAAAACCUGUUAAUUUUUAUACUGACAAUAAAAAUGUUUCUACAGA
UAUUAAUGUUAACAAGACAAAAUAAAUGUCACGCAACUUAAAAAAAAAAAAAAAA
<SEQ ID NO. 3407;RNA;Artificial Sequence> ggcggcggcuggaggagag
<SEQ ID NO. 3408;RNA;Artificial Sequence> gcgcgguggagagccgagc
<SEQ ID NO. 3409;RNA;Artificial Sequence> cgggcgggcggcgggugcg
<SEQ ID NO. 3410;RNA;Artificial Sequence> ggagcgggcgagggagcgc
<SEQ ID NO. 3411;RNA;Artificial Sequence> cgcgcggccgccacaaagc
<SEQ ID NO. 3412;RNA;Artificial Sequence> cucgggcgccgcggggcug
<SEQ ID NO. 3413;RNA;Artificial Sequence> gcaugcggcguaccuggcc
<SEQ ID NO. 3414;RNA;Artificial Sequence> ccggcgcggcgacugcucu
<SEQ ID NO. 3415;RNA;Artificial Sequence> uccgggcuggcgggggccg
<SEQ ID NO. 3416;RNA;Artificial Sequence> ggccgcgagccccgggggc
<SEQ ID NO. 3417;RNA;Artificial Sequence> ccccgaggccgcagcuugc
<SEQ ID NO. 3418;RNA;Artificial Sequence> ccugcgcgcucugagccuu
<SEQ ID NO. 3419;RNA;Artificial Sequence> ucgcaacucgcgagcaaag
<SEQ ID NO. 3420;RNA;Artificial Sequence> guuugguggaggcaacgcc
<SEQ ID NO. 3421;RNA;Artificial Sequence> caagccugaguccuuucuu
<SEQ ID NO. 3422;RNA;Artificial Sequence> uccucucguuccccaaauc
<SEQ ID NO. 3423;RNA;Artificial Sequence> ccgagggcagcccgcgggc
<SEQ ID NO. 3424;RNA;Artificial Sequence> cgucaugcccgcgcuccuc
<SEQ ID NO. 3425;RNA;Artificial Sequence> ccgcagccugggguacgcg
<SEQ ID NO. 3426;RNA;Artificial Sequence> gugaagcccgggaggcuug
<SEQ ID NO. 3427;RNA;Artificial Sequence> ggcgccggcgaagacccaa
741-3724

CA 02677068 2009-09-01
<SEQ ID NO. 3428;RNA;Artificial Sequence> aggaccacucuucugcguu
<SEQ ID NO. 3429;RNA;Artificial Sequence> uuggaguugcuccccgcaa
<SEQ ID NO. 3430;RNA;Artificial Sequence> accccgggcucgucgcuuu
<SEQ ID NO. 3431;RNA;Artificial Sequence> ucuccaucccgacccacgc
<SEQ ID NO. 3432;RNA;Artificial Sequence> cggggcgeggggacaacac
<SEQ ID NO. 3433;RNA;Artificial Sequence> caggucgcggaggagcguu
<SEQ ID NO. 3434;RNA;Artificial Sequence> ugccauucaagugacugca
<SEQ ID NO. 3435;RNA; Artificial Sequence> agcagcagcggcagcgccu
<SEQ ID NO. 3436;RNA;Artificial Sequence> ucgguuccugagcccaccg
<SEQ ID NO. 3437;RNA;Artificial Sequence> gcaggcugaaggcauugcg
<SEQ ID NO. 3438;RNA;Artificial Sequence> gcguaguccaugcccguag
<SEQ ID NO. 3439;RNA;Artificial Sequence> gaggaagugugcagauggg
<SEQ ID NO. 3440;RNA;Artificial Sequence> gauuaacguccacauggag
<SEQ ID NO. 3441;RNA;Artificial Sequence> gauauggaagaggaccggg
<SEQ ID NO. 3442;RNA;Artificial Sequence> ggauugguaccguaaccau
<SEQ ID NO. 3443;RNA;Artificial Sequence> uggucagcuggggucguuu
<SEQ ID NO. 3444;RNA;Artificial Sequence> ucaucugccuggucguggu
<SEQ ID NO. 3445;RNA;Artificial Sequence> ucaccauggcaaccuuguc
<SEQ ID NO. 3446;RNA;Artificial Sequence> cccuggcccggcccuccuu
<SEQ ID NO. 3447;RNA;Artificial Sequence> ucaguuuaguugaggauac
<SEQ ID NO. 3448;RNA;Artificial Sequence> ccacauuagagccagaaga
<SEQ ID NO. 3449;RNA;Artificial Sequence> agccaccaaccaaauacca
<SEQ ID NO. 3450;RNA;Artificial Sequence> aaaucucucaaccagaagu
<SEQ ID NO. 3451;RNA;Artificial Sequence> uguacguggcugcgccagg
<SEQ ID NO. 3452;RNA; Artificial Sequence> gggagucgcuagaggugcg
<SEQ ID NO. 3453;RNA;Artificial Sequence> gcugccuguugaaagaugc
<SEQ ID NO. 3454;RNA;Artificial Sequence> ccgccgugaucaguuggac
<SEQ ID NO. 3455;RNA;Artificial Sequence> cuaaggauggggugcacuu
<SEQ ID NO. 3456;RNA;Artificial Sequence> uggggcccaacaauaggac
<SEQ ID NO. 3457;RNA;Artificial Sequence> cagugcuuauuggggagua
<SEQ ID NO. 3458;RNA;Artificial Sequence> acuugcagauaaagggcgc
<SEQ ID NO. 3459;RNA;Artificial Sequence> ccacgccuagagacuccgg
<SEQ ID NO. 3460;RNA;Artificial Sequence> gccucuaugcuuguacugc
<SEQ ID NO. 3461;RNA;Artificial Sequence> ccaguaggacuguagacag
<SEQ ID NO. 3462;RNA;Artificial Sequence> gugaaacuugguacuucau
<SEQ ID NO. 3463;RNA;Artificial Sequence> uggugaaugucacagaugc
<SEQ ID NO. 3464;RNA;Artificial Sequence> ccaucucauccggagauga
<SEQ ID NO. 3465;RNA;Artificial Sequence> augaggaugacaccgaugg
<SEQ ID NO. 3466;RNA;Artificial Sequence> gugcggaagauuuugucag
<SEQ ID NO. 3467;RNA;Artificial Sequence> gugagaacaguaacaacaa
<SEQ ID NO. 3468;RNA;Artificial Sequence> agagagcaccauacuggac
<SEQ ID NO.3469;RNA;Artificial Sequence> ccaacacagaaaagaugga
<SEQ ID NO. 3470;RNA;Artificial Sequence> aaaagcggcuccaugcugu
<SEQ ID NO. 3471;RNA;Artificial Sequence> ugccugcggccaacacugu
<SEQ ID NO. 3472;RNA;Artificial Sequence> ucaaguuucgcugcccagc
<SEQ ID NO. 3473;RNA;Artificial Sequence> ccggggggaacccaaugcc
<SEQ ID NO. 3474;RNA;Artificial Sequence> caaccaugcgguggcugaa
<SEQ ID NO. 3475;RNA;Artificial Sequence> aaaacgggaaggaguuuaa
<SEQ ID NO. 3476;RNA;Artificial Sequence> agcaggagcaucgcauugg
<SEQ ID NO. 3477;RNA;Artificial Sequence> gaggcuacaagguacgaaa
<SEQ ID NO. 3478;RNA;Artificial Sequence> accagcacuggagccucau
<SEQ ID NO. 3479;RNA;Artificial Sequence> uuauggaaagugugguccc
<SEQ ID NO. 3480;RNA;Artificial Sequence> caucugacaagggaaauua
<SEQ ID NO. 3481;RNA;Artificial Sequence> auaccuguguaguggagaa
<SEQ ID NO. 3482;RNA;Artificial Sequence> augaauacggguccaucaa
<SEQ ID NO. 3483;RNA;Artificial Sequence> aucacacguaccaccugga
<SEQ ID NO. 3484;RNA;Artificial Sequence> auguuguggagcgaucgcc
<SEQ ID NO. 3485;RNA;Artificial Sequence> cucaccggcccauccucca
<SEQ ID NO. 3486;RNA;Artificial Sequence> aagccggacugccggcaaa
<SEQ ID NO. 3487;RNA;Artificial Sequence> augccuccacaguggucgg
<SEQ ID NO. 3488;RNA;Artificial Sequence> gaggagacguagaguuugu
<SEQ ID NO. 3489;RNA;Artificial Sequence> ucugcaagguuuacaguga
<SEQ ID NO. 3490;RNA;Artificial Sequence> augcccagccccacaucca
<SEQ ID NO. 3491;RNA;Artificial Sequence> aguggaucaagcacgugga
<SEQ ID NO. 3492;RNA;Artificial Sequence> aaaagaacggcaguaaaua
<SEQ ID NO. 3493;RNA;Artificial Sequence> acgggcccgacgggcugcc
<SEQ ID NO. 3494;RNA;Artificial Sequence> ccuaccucaagguucucaa
<SEQ ID NO. 3495;RNA;Artificial Sequence> aggccgccgguguuaacac
<SEQ ID NO. 3496;RNA;Artificial Sequence> ccacggacaaagagauuga
<SEQ ID NO. 3497;RNA;Artificial Sequence> agguucucuauauucggaa
<SEQ ID NO.3498;RNA;Artificial Sequence> auguaacuuuugaggacgc
<SEQ ID NO. 3499;RNA;Artificial Sequence> cuggggaauauacgugcuu
<SEQ ID NO. 3500;RNA;Artificial Sequence> uggcggguaauucuauugg
741-3725

CA 02677068 2009-09-01
<SEQ ID NO. 3501;RNA;Artificial Sequence> ggauauccuuucacucugc
<SEQ ID NO. 3502;RNA;Artificial Sequence> caugguugacaguucugcc
<SEQ ID NO. 3503;RNA;Artificial Sequence> cagcgccuggaagagaaaa
<SEQ ID NO. 3504;RNA;Artificial Sequence> aggagauuacagcuucccc
<SEQ ID NO. 3505;RNA;Artificial Sequence> cagacuaccuggagauagc
<SEQ ID NO. 3506;RNA;Artificial Sequence> ccauuuacugcauaggggu
<SEQ ID NO. 3507;RNA;Artificial Sequence> ucuucuuaaucgccuguau
<SEQ ID NO. 3508;RNA;Artificial Sequence> uggugguaacagucauccu
<SEQ ID NO.3509;RNA;Artificial Sequence> ugugccgaaugaagaacac
<SEQ ID NO. 35 1 0;RNA;Artificial Sequence> cgaccaagaagccagacuu
<SEQ ID NO. 3511;RNA;Artificial Sequence> ucagcagccagccggcugu
<SEQ ID NO. 3512;RNA;Artificial Sequence> ugcacaagcugaccaaacg
<SEQ ID NO. 3513;RNA;Artificial Sequence> guaucccccugcggagaca
<SEQ ID NO. 3514;RNA;Artificial Sequence> agguaacaguuucggcuga
<SEQ ID NO. 3515;RNA;Artificial Sequence> aguccagcuccuccaugaa
<SEQ ID NO. 3516;RNA;Artificial Sequence> acuccaacaccccgcuggu
<SEQ ID NO. 3517;RNA;Artificial Sequence> ugaggauaacaacacgccu
<SEQ ID NO. 3518;RNA;Artificial Sequence> ucucuucaacggcagacac
<SEQ ID NO. 3519;RNA;Artificial Sequence> cccccaugcuggcaggggu
<SEQ ID NO. 3520;RNA;Artificial Sequence> ucuccgaguaugaacuucc
<SEQ ID NO. 3521;RNA;Artificial Sequence> cagaggacccaaaauggga
<SEQ ID NO. 3522;RNA;Artificial Sequence> aguuuccaagagauaagcu
<SEQ ID NO. 3523;RNA;Artificial Sequence> ugacacugggcaagccccu
<SEQ ID NO. 3524;RNA;Artificial Sequence> ugggagaagguugcuuugg
<SEQ ID NO. 3525;RNA;Artificial Sequence> ggcaaguggucauggcgga
<SEQ ID NO. 3526;RNA;Artificial Sequence> aagcagugggaauugacaa
<SEQ ID NO. 3527;RNA;Artificial Sequence> aagacaagcccaaggaggc
<SEQ ID NO. 3528;RNA;Artificial Sequence> cggucaccguggccgugaa
<SEQ ID NO. 3529;RNA;Artificial Sequence> agauguugaaagaugaugc
<SEQ ID NO. 3530;RNA;Artificial Sequence> ccacagagaaagaccuuuc
<SEQ ID NO. 3531;RNA;Artificial Sequence> cugaucuggugucagagau
<SEQ ID NO. 3532;RNA;Artificial Sequence> uggagaugaugaagaugau
<SEQ ID NO. 3533;RNA;Artificial Sequence> uugggaaacacaagaauau
<SEQ ID NO. 3534;RNA;Artificial Sequence> ucauaaaucuucuuggagc
<SEQ ID NO. 3535;RNA;Artificial Sequence> ccugcacacaggaugggcc
<SEQ ID NO. 3536;RNA;Artificial Sequence> cucucuaugucauaguuga
<SEQ ID NO. 3537;RNA;Artificial Sequence> aguaugccucuaaaggcaa
<SEQ ID NO. 3538;RNA;Artificial Sequence> accuccgagaauaccuccg
<SEQ ID NO.3539;RNA;Artificial Sequence> gagcccggaggccacccgg
<SEQ ID NO. 3540;RNA;Artificial Sequence> ggauggaguacuccuauga
<SEQ ID NO. 3541;RNA;Artificial Sequence> acauuaaccguguuccuga
<SEQ ID NO. 3542;RNA;Artificial Sequence> aggagcagaugaccuucaa
<SEQ ID NO. 3543;RNA;Artificial Sequence> aggacuuggugucaugcac
<SEQ ID NO. 3544;RNA;Artificial Sequence> ccuaccagcuggccagagg
<SEQ ID NO. 3545;RNA;Artificial Sequence> gcauggaguacuuggcuuc
<SEQ ID NO. 3546;RNA;Artificial Sequence> cccaaaaauguauucaucg
<SEQ ID NO. 3547;RNA;Artificial Sequence> gagauuuagcagccagaaa
<SEQ ID NO. 3548;RNA;Artificial Sequence> auguuuugguaacagaaaa
<SEQ ID NO. 3549;RNA;Artificial Sequence> acaaugugaugaaaauagc
<SEQ ID NO. 3550;RNA;Artificial Sequence> cagacuuuggacucgccag
<SEQ ID NO. 3551;RNA;Artificial Sequence> gagauaucaacaauauaga
<SEQ ID NO. 3552;RNA;Artificial Sequence> acuauuacaaaaagaccac
<SEQ ID NO. 3553;RNA;Artificial Sequence> ccaaugggcggcuuccagu
<SEQ ID NO. 3554;RNA;Artificial Sequence> ucaaguggauggcuccaga
<SEQ ID NO. 3555;RNA;Artificial Sequence> aagcccuguuugauagagu
<SEQ ID NO. 3556;RNA;Artificial Sequence> uauacacucaucagaguga
<SEQ ID NO. 3557;RNA;Artificial Sequence> augucugguccuucggggu
<SEQ ID NO. 3558;RNA;Artificial Sequence> uguuaaugugggagaucuu
<SEQ ID NO. 3559;RNA;Artificial Sequence> ucacuuuagggggcucgcc
<SEQ ID NO. 3560;RNA;Artificial Sequence> ccuacccagggauucccgu
<SEQ ID NO. 3561;RNA;Artificial Sequence> uggaggaacuuuuuaagcu
<SEQ ID NO. 3562;RNA;Artificial Sequence> ugcugaaggaaggacacag
<SEQ ID NO. 3563;RNA;Artificial Sequence> gaauggauaagccagccaa
<SEQ ID NO. 3564;RNA;Artificial Sequence> acugcaccaacgaacugua
<SEQ ID NO. 3565;RNA;Artificial Sequence> acaugaugaugagggacug
<SEQ ID NO. 3566;RNA;Artificial Sequence> guuggcaugcagugcccuc
<SEQ ID NO. 3567;RNA;Artificial Sequence> cccagagaccaacguucaa
<SEQ ID NO. 3568;RNA;Artificial Sequence> agcaguugguagaagacuu
<SEQ ID NO. 3569;RNA;Artificial Sequence> uggaucgaauucucacucu
<SEQ ID NO. 3570;RNA;Artificial Sequence> ucacaaccaaugaggaaua
<SEQ ID NO. 3571;RNA;Artificial Sequence> acuuggaccucagccaacc
<SEQ ID NO. 3572;RNA;Artificial Sequence> cucucgaacaguauucacc
<SEQ ID NO. 3573;RNA;Artificial Sequence> cuaguuacccugacacaag
741-3726

CA 02677068 2009-09-01
<SEQ ID NO. 3574;RNA;Artificial Sequence> gaaguucuuguucuucagg
<SEQ ID NO. 3575;RNA;Artificial Sequence> gagaugauucuguuuuuuc
<SEQ ID NO. 3576;RNA;Artificial Sequence> cuccagaccccaugccuua
<SEQ ID NO. 3577;RNA;Artificial Sequence> acgaaccaugccuuccuca
<SEQ ID NO. 3578;RNA;Artificial Sequence> aguauccacacauaaacgg
<SEQ ID NO. 3579;RNA;Artificial Sequence> gcaguguuaaaacaugaau
<SEQ ID NO. 3580;RNA;Artificial Sequence> ugacugugucugccugucc
<SEQ ID NO. 3581;RNA;Artificial Sequence> cccaaacaggacagcacug
<SEQ ID NO. 3582;RNA;Artificial Sequence> gggaaccuagcuacacuga
<SEQ ID NO. 3583;RNA;Artificial Sequence> agcagggagaccaugccuc
<SEQ ID NO. 3584;RNA;Artificial Sequence> cccagagcuuguugucucc
<SEQ ID NO. 3585;RNA;Artificial Sequence> cacuuguauauauggauca
<SEQ ID NO. 3586;RNA;Artificial Sequence> agaggaguaaauaauugga
<SEQ ID NO.3587;RNA;Artificial Sequence> aaaaguaaucagcauaugu
<SEQ ID NO. 3588;RNA;Artificial Sequence> uguaaagauuuauacaguu
<SEQ ID NO. 3589;RNA;Artificial Sequence> ugaaaacuuguaaucuucc
<SEQ ID NO. 3590;RNA;Artificial Sequence> cccaggaggagaagaaggu
<SEQ ID NO. 3591;RNA;Artificial Sequence> uuucuggagcaguggacug
<SEQ ID NO. 3592;RNA;Artificial Sequence> gccacaagccaccauguaa
<SEQ ID NO. 3593;RNA;Artificial Sequence> accccucucaccugccgug
<SEQ ID NO. 3594;RNA;Artificial Sequence> gcguacuggcuguggacca
<SEQ ID NO. 3595;RNA;Artificial Sequence> aguaggacucaagguggac
<SEQ ID NO. 3596;RNA;Artificial Sequence> cgugcguucugccuuccuu
<SEQ ID NO. 3597;RNA;Artificial Sequence> uguuaauuuuguaauaauu
<SEQ ID NO. 3598;RNA;Artificial Sequence> uggagaagauuuaugucag
<SEQ ID NO. 3599;RNA;Artificial Sequence> gcacacacuuacagagcac
<SEQ ID NO. 3600;RNA;Artificial Sequence> caaaugcaguauauaggug
<SEQ ID NO. 3601;RNA;Artificial Sequence> gcuggauguauguaaauau
<SEQ ID NO. 3602;RNA;Artificial Sequence> uauucaaauuauguauaaa
<SEQ ID NO. 3603;RNA;Artificial Sequence> auauauauuauauauuuac
<SEQ ID NO. 3604;RNA;Artificial Sequence> caaggaguuauuuuuugua
<SEQ ID NO. 3605;RNA;Artificial Sequence> auugauuuuaaauggaugu
<SEQ ID NO. 3606;RNA;Artificial Sequence> ucccaaugcaccuagaaaa
<SEQ ID NO. 3607;RNA;Artificial Sequence> auuggucucucuuuuuuua
<SEQ ID NO. 3608;RNA;Artificial Sequence> aauagcuauuugcuaaaug
<SEQ ID NO. 3609;RNA;Artificial Sequence> gcuguucuuacacauaauu
<SEQ ID NO. 3610;RNA;Artificial Sequence> uucuuaauuuucaccgagc
<SEQ ID NO. 3611;RNA;Artificial Sequence> cagagguggaaaaauacuu
<SEQ ID NO. 3612;RNA;Artificial Sequence> uuugcuuucagggaaaaug
<SEQ ID NO. 3613;RNA;Artificial Sequence> gguauaacguuaauuuauu
<SEQ ID NO. 3614;RNA;Artificial Sequence> uaauaaauugguaauauac
<SEQ ID NO.3615;RNA;Artificial Sequence> caaaacaauuaaucauuua
<SEQ ID NO. 3616;RNA;Artificial Sequence> auaguuuuuuuuguaauuu
<SEQ ID NO. 3617;RNA;Artificial Sequence> uaaguggcauuucuaugca
<SEQ ID NO.3618;RNA;Artificial Sequence> aggcagcacagcagacuag
<SEQ ID NO. 3619;RNA;Artificial Sequence> guuaaucuauugcuuggac
<SEQ ID NO. 3620;RNA;Artificial Sequence> cuuaacuaguuaucagauc
<SEQ ID NO. 3621;RNA;Artificial Sequence> ccuuugaaaagagaauauu
<SEQ ID NO. 3622;RNA;Artificial Sequence> uuacaauauaugacuaauu
<SEQ ID NO. 3623;RNA;Artificial Sequence> uuggggaaaaugaaguuuu
<SEQ ID NO. 3624;RNA;Artificial Sequence> ugauuuauuuguguuuaaa
<SEQ ID NO. 3625;RNA;Artificial Sequence> augcugcugucagacgauu
<SEQ ID NO. 3626;RNA; Artificial Sequence> uguucuuagaccuccuaaa
<SEQ ID NO. 3627;RNA;Artificial Sequence> augccccauauuaaaagaa
<SEQ ID NO. 3628;RNA;Artificial Sequence> acucauucauaggaaggug
<SEQ ID NO. 3629;RNA;Artificial Sequence> guuucauuuuggugugcaa
<SEQ ID NO. 3630;RNA;Artificial Sequence> acccugucauuacgucaac
<SEQ ID NO. 3631;RNA;Artificial Sequence> cgcaacgucuaacuggacu
<SEQ ID NO. 3632;RNA;Artificial Sequence> uucccaagauaaaugguac
<SEQ ID NO. 3633;RNA;Artificial Sequence> ccagcguccucuuaaaaga
<SEQ ID NO. 3634;RNA;Artificial Sequence> augccuuaauccauuccuu
<SEQ ID NO. 3635;RNA;Artificial Sequence> ugaggacagaccuuaguug
<SEQ ID NO. 3636;RNA;Artificial Sequence> gaaaugauagcagaaugug
<SEQ ID NO. 3637;RNA;Artificial Sequence> gcuucucucuggcagcugg
<SEQ ID NO. 3638;RNA;Artificial Sequence> gccuucugcuucugaguug
<SEQ ID NO. 3639;RNA;Artificial Sequence> gcacauuaaucagauuagc
<SEQ ID NO. 3640;RNA;Artificial Sequence> ccuguauucucuucaguga
<SEQ ID NO. 3641;RNA;Artificial Sequence> aauuuugauaauggcuucc
<SEQ ID NO. 3642;RNA;Artificial Sequence> cagacucuuuggcguugga
<SEQ ID NO. 3643;RNA;Artificial Sequence> agacgccuguuaggaucuu
<SEQ ID NO. 3644;RNA;Artificial Sequence> ucaagucccaucauagaaa
<SEQ ID NO. 3645;RNA;Artificial Sequence> aauugaaacacagaguugu
<SEQ ID NO. 3646;RNA;Artificial Sequence> uucugcugauaguuuuggg
741-3727

CA 02677068 2009-09-01
<SEQ ID NO. 3647;RNA;Artificial Sequence> ggauacguccaucuuuuua
<SEQ ID NO. 3648;RNA;Artificial Sequence> aagggauugcuuucaucua
<SEQ ID NO. 3649;RNA;Artificial Sequence> aauucuggcaggaccucac
<SEQ ID NO. 3650;RNA;Artificial Sequence> ccaaaagauccagccucau
<SEQ ID NO.3651;RNA;Artificial Sequence> uaccuacaucagacaaaau
<SEQ ID NO. 3652;RNA;Artificial Sequence> uaucgccguuguuccuucu
<SEQ ID NO. 3653;RNA;Artificial Sequence> uguacuaaaguauuguguu
<SEQ ID NO. 3654;RNA;Artificial Sequence> uuugcuuuggaaacaccca
<SEQ ID NO. 3655;RNA;Artificial Sequence> acucacuuugcaauagccg
<SEQ ID NO. 3656;RNA;Artificial Sequence> gugcaagaugaaugcagau
<SEQ ID NO. 3657;RNA;Artificial Sequence> uuacacugaucuuaugugu
<SEQ ID NO. 3658;RNA;Artificial Sequence> uuacaaaauuggagaaagu
<SEQ ID NO. 3659;RNA;Artificial Sequence> uauuuaauaaaaccuguua
<SEQ ID NO. 3660;RNA;Artificial Sequence> aauuuuuauacugacaaua
<SEQ ID NO. 3661;RNA;Artificial Sequence> aaaaauguuucuacagaua
<SEQ ID NO. 3662;RNA;Artificial Sequence> auuaauguuaacaagacaa
<SEQ ID NO. 3663;RNA;Artificial Sequence> aaauaaaugucacgcaacu
<SEQ ID NO. 3664;RNA;Artificial Sequence> agcacucggggauaaauag
<SEQ ID NO. 3665;RNA;Artificial Sequence> guuccaaugcagaagugcu
<SEQ ID NO. 3666;RNA;Artificial Sequence> uggcucuguucaaugugac
<SEQ ID NO. 3667;RNA;Artificial Sequence> ccgaggcggaugcugggga
<SEQ ID NO. 3668;RNA;Artificial Sequence> aauauauauguaaggucuc
<SEQ ID NO. 3669;RNA;Artificial Sequence> ccaauuauauagggcaggc
<SEQ ID NO. 3670;RNA;Artificial Sequence> ccaaccagucugccuggcu
<SEQ ID NO. 3671;RNA;Artificial Sequence> ucacuguccugccaaaaca
<SEQ ID NO. 3672;RNA;Artificial Sequence> agcaagcgccuggaagaga
<SEQ ID NO. 3673;RNA;Artificial Sequence> aaaaggagauuacagcuuc
<SEQ ID NO. 3674;RNA;Artificial Sequence> ccccagacuaccuggagau
<SEQ ID NO. 3675;RNA;Artificial Sequence> uagccauuuacugcauagg
<SEQ ID NO. 3676;RNA;Artificial Sequence> gggucuucuuaaucgccug
<SEQ ID NO. 3677;RNA;Artificial Sequence> guauggugguaacagucau
<SEQ ID NO. 3678;RNA;Artificial Sequence> uccugugccgaaugaagaa
<SEQ ID NO. 3679;RNA;Artificial Sequence> acacgaccaagaagccaga
<SEQ ID NO. 3680;RNA;Artificial Sequence> acuucagcagccagccggc
<SEQ ID NO. 3681;RNA;Artificial Sequence> cugugcacaagcugaccaa
<SEQ ID NO. 3682;RNA;Artificial Sequence> aacguaucccccugcggag
<SEQ ID NO. 3683;RNA;Artificial Sequence> gacagguaacaguuucggc
<SEQ ID NO. 3684;RNA;Artificial Sequence> cugaguccagcuccuccau
<SEQ ID NO. 3685;RNA;Artificial Sequence> ugaacuccaacaccccgcu
<SEQ ID NO. 3686;RNA;Artificial Sequence> uggugaggauaacaacacg
<SEQ ID NO. 3687;RNA;Artificial Sequence> gccucucuucaacggcaga
<SEQ ID NO. 3688;RNA;Artificial Sequence> acacccccaugcuggcagg
<SEQ ID NO. 3689;RNA;Artificial Sequence> gggucuccgaguaugaacu
<SEQ ID NO. 3690;RNA;Artificial Sequence> uuccagaggacccaaaaug
<SEQ ID NO. 3691;RNA;Artificial Sequence> gggaguuuccaagagauaa
<SEQ ID NO. 3692;RNA;Artificial Sequence> agcugacacugggcaagcc
<SEQ ID NO. 3693;RNA;Artificial Sequence> cccugggagaagguugcuu
<SEQ ID NO. 3694;RNA;Artificial Sequence> uugggcaaguggucauggc
<SEQ ID NO. 3695;RNA;Artificial Sequence> cggaagcagugggaauuga
<SEQ ID NO. 3696;RNA;Artificial Sequence> acaaagacaagcccaagga
<SEQ ID NO. 3697;RNA;Artificial Sequence> aggcggucaccguggccgu
<SEQ ID NO. 3698;RNA;Artificial Sequence> ugaagauguugaaagauga
<SEQ ID NO. 3699;RNA;Artificial Sequence> augccacagagaaagaccu
<SEQ ID NO. 3700;RNA;Artificial Sequence> uuucugaucuggugucaga
<SEQ ID NO. 3701;RNA;Artificial Sequence> agauggagaugaugaagau
<SEQ ID NO. 3702;RNA;Artificial Sequence> ugauugggaaacacaagaa
<SEQ ID NO. 3703;RNA;Artificial Sequence> auaucauaaaucuucuugg
<SEQ ID NO. 3704;RNA;Artificial Sequence> gagccugcacacaggaugg
<SEQ ID NO. 3705;RNA;Artificial Sequence> ggccucucuaugucauagu
<SEQ ID NO. 3706;RNA;Artificial Sequence> uugaguaugccucuaaagg
<SEQ ID NO. 3707;RNA;Artificial Sequence> gcaaccuccgagaauaccu
<SEQ ID NO. 3708;RNA;Artificial Sequence> uccgagcccggaggccacc
<SEQ ID NO. 3709;RNA;Artificial Sequence> ccgggauggaguacuccua
<SEQ ID NO. 3710;RNA;Artificial Sequence> augacauuaaccguguucc
<SEQ ID NO. 3711;RNA;Artificial Sequence> cugaggagcagaugaccuu
<SEQ ID NO. 3712;RNA;Artificial Sequence> ucaaggacuuggugucaug
<SEQ ID NO.3713;RNA;Artificial Sequence> gcaccuaccagcuggccag
<SEQ ID NO. 3714;RNA;Artificial Sequence> gaggcauggaguacuuggc
<SEQ ID NO. 3715;RNA;Artificial Sequence> cuucccaaaaauguauuca
<SEQ ID NO. 3716;RNA;Artificial Sequence> aucgagauuuagcagccag
<SEQ ID NO. 3717;RNA;Artificial Sequence> gaaauguuuugguaacaga
<SEQ ID NO. 37 1 8;RNA;Artificial Sequence> aaaacaaugugaugaaaau
<SEQ ID NO. 3719;RNA;Artificial Sequence> uagcagacuuuggacucgc
741-3728

CA 02677068 2009-09-01
<SEQ ID NO. 3720;RNA;Artificial Sequence> ccagagauaucaacaauau
<SEQ ID NO. 3721;RNA;Artificial Sequence> uagacuauuacaaaaagac
<SEQ ID NO. 3722;RNA;Artificial Sequence> ccaccaaugggcggcuucc
<SEQ ID NO. 3723;RNA;Artificial Sequence> cagucaaguggauggcucc
<SEQ ID NO. 3724;RNA;Artificial Sequence> cagaagcccuguuugauag
<SEQ ID NO. 3725;RNA;Artificial Sequence> gaguauacacucaucagag
<SEQ ID NO. 3726;RNA;Artificial Sequence> gugaugucugguccuucgg
<SEQ ID NO. 3727;RNA;Artificial Sequence> ggguguuaaugugggagau
<SEQ ID NO. 3728;RNA;Artificial Sequence> ucuucacuuuagggggcuc
<SEQ ID NO. 3729;RNA;Artificial Sequence> cgcccuacccagggauucc
<SEQ ID NO. 3730;RNA;Artificial Sequence> ccguggaggaacuuuuuaa
<SEQ ID NO. 3731;RNA;Artificial Sequence> agcugcugaaggaaggaca
<SEQ ID NO. 3732;RNA;Artificial Sequence> acagaauggauaagccagc
<SEQ ID NO. 3733;RNA;Artificial Sequence> ccaacugcaccaacgaacu
<SEQ ID NO. 3734;RNA;Artificial Sequence> uguacaugaugaugaggga
<SEQ ID NO. 3735;RNA;Artificial Sequence> acuguuggcaugcagugcc
<SEQ ID NO. 3736;RNA;Artificial Sequence> ccucccagagaccaacguu
<SEQ ID NO. 3737;RNA;Artificial Sequence> ucaagcaguugguagaaga
<SEQ ID NO. 3738;RNA;Artificial Sequence> acuuggaucgaauucucac
<SEQ ID NO. 3739;RNA;Artificial Sequence> cucucacaaccaaugagga
<SEQ ID NO. 3740;RNA;Artificial Sequence> aauacuuggaccucagcca
<SEQ ID NO. 3741;RNA;Artificial Sequence> aaccucucgaacaguauuc
<SEQ ID NO. 3742;RNA;Artificial Sequence> caccuaguuacccugacac
<SEQ ID NO. 3743;RNA;Artificial Sequence> caagaaguucuuguucuuc
<SEQ ID NO. 3744;RNA;Artificial Sequence> caggagaugauucuguuuu
<SEQ ID NO. 3745;RNA;Artificial Sequence> uuucuccagaccccaugcc
<SEQ ID NO. 3746;RNA;Artificial Sequence> cuuacgaaccaugccuucc
<SEQ ID NO. 3747;RNA;Artificial Sequence> cucaguauccacacauaaa
<SEQ ID NO. 3748;RNA;Artificial Sequence> acggcaguguuaaaacaug
<SEQ ID NO. 3749;RNA;Artificial Sequence> gaaugacugugucugccug
<SEQ ID NO. 3750;RNA;Artificial Sequence> guccccaaacaggacagca
<SEQ ID NO. 3751;RNA;Artificial Sequence> acugggaaccuagcuacac
<SEQ ID NO. 3752;RNA;Artificial Sequence> cugagcagggagaccaugc
<SEQ ID NO. 3753;RNA;Artificial Sequence> ccucccagagcuuguuguc
<SEQ ID NO. 3754;RNA;Artificial Sequence> cuccacuuguauauaugga
<SEQ ID NO. 3755;RNA; Artificial Sequence> aucagaggaguaaauaauu
<SEQ ID NO.3756;RNA;Artificial Sequence> uggaaaaguaaucagcaua
<SEQ ID NO. 3757;RNA;Artificial Sequence> auguguaaagauuuauaca
<SEQ ID NO. 3758;RNA;Artificial Sequence> aguugaaaacuuguaaucu
<SEQ ID NO. 3759;RNA;Artificial Sequence> uuccccaggaggagaagaa
<SEQ ID NO. 3760;RNA;Artificial Sequence> agguuucuggagcagugga
<SEQ ID NO. 3761;RNA;Artificial Sequence> acugccacaagccaccaug
<SEQ ID NO. 3762;RNA;Artificial Sequence> guaaccccucucaccugcc
<SEQ ID NO. 3763;RNA; Artificial Sequence> cgugcguacuggcugugga
<SEQ ID NO. 3764;RNA;Artificial Sequence> accaguaggacucaaggug
<SEQ ID NO. 3765;RNA;Artificial Sequence> ggacgugcguucugccuuc
<SEQ ID NO. 3766;RNA;Artificial Sequence> ccuuguuaauuuuguaaua
<SEQ ID NO. 3767;RNA;Artificial Sequence> aauuggagaagauuuaugu
<SEQ ID NO. 3768;RNA; Artificial Sequence> ucagcacacacuuacagag
<SEQ ID NO. 3769;RNA;Artificial Sequence> gcacaaaugcaguauauag
<SEQ ID NO. 3770;RNA;Artificial Sequence> ggugcuggauguauguaaa
<SEQ ID NO. 3771;RNA;Artificial Sequence> auauauucaaauuauguau
<SEQ ID NO. 3772;RNA;Artificial Sequence> uaaauauauauuauauauu
<SEQ ID NO. 3773;RNA;Artificial Sequence> uuacaaggaguuauuuuuu
<SEQ ID NO. 3774;RNA;Artificial Sequence> uguauugauuuuaaaugga
<SEQ ID NO. 3775;RNA;Artificial Sequence> augucccaaugcaccuaga
<SEQ ID NO. 3776;RNA;Artificial Sequence> aaaauuggucucucuuuuu
<SEQ ID NO. 3777;RNA;Artificial Sequence> uuuaauagcuauuugcuaa
<SEQ ID NO. 3778;RNA;Artificial Sequence> aaugcuguucuuacacaua
<SEQ ID NO. 3779;RNA;Artificial Sequence> aauuucuuaauuuucaccg
<SEQ ID NO. 3780;RNA;Artificial Sequence> gagcagagguggaaaaaua
<SEQ ID NO. 3781;RNA;Artificial Sequence> acuuuugcuuucagggaaa
<SEQ ID NO. 3782;RNA;Artificial Sequence> aaugguauaacguuaauuu
<SEQ ID NO. 3783;RNA;Artificial Sequence> uauuaauaaauugguaaua
<SEQ ID NO. 3784;RNA;Artificial Sequence> auacaaaacaauuaaucau
<SEQ ID NO. 3785;RNA;Artificial Sequence> uuuauaguuuuuuuuguaa
<SEQ ID NO. 3786;RNA;Artificial Sequence> auuuaaguggcauuucuau
<SEQ ID NO. 3787;RNA;Artificial Sequence> ugcaggcagcacagcagac
<SEQ ID NO. 3788;RNA;Artificial Sequence> cuaguuaaucuauugcuug
<SEQ ID NO. 3789;RNA;Artificial Sequence> ggacuuaacuaguuaucag
<SEQ ID NO. 3790;RNA;Artificial Sequence> gauccuuugaaaagagaau
<SEQ ID NO. 3791;RNA;Artificial Sequence> uauuuacaauauaugacua
<SEQ ID NO. 3792;RNA;Artificial Sequence> aauuuggggaaaaugaagu
741-3729

CA 02677068 2009-09-01
<SEQ ID NO. 3793;RNA;Artificial Sequence> uuuugauuuauuuguguuu
<SEQ ID NO. 3794;RNA;Artificial Sequence> uaaaugcugcugucagacg
<SEQ ID NO. 3795;RNA;Artificial Sequence> gauuguucuuagaccuccu
<SEQ ID NO. 3796;RNA;Artificial Sequence> uaaaugccccauauuaaaa
<SEQ ID NO. 3797;RNA;Artificial Sequence> agaacucauucauaggaag
<SEQ ID NO. 3798;RNA;Artificial Sequence> gguguuucauuuuggugug
<SEQ ID NO. 3799;RNA;Artificial Sequence> gcaacccugucauuacguc
<SEQ ID NO. 3800;RNA;Artificial Sequence> caacgcaacgucuaacugg
<SEQ ID NO. 3801;RNA;Artificial Sequence> gacuucccaagauaaaugg
<SEQ ID NO. 3802;RNA;Artificial Sequence> guaccagcguccucuuaaa
<SEQ ID NO. 3803;RNA;Artificial Sequence> aagaugccuuaauccauuc
<SEQ ID NO. 3804;RNA;Artificial Sequence> ccuugaggacagaccuuag
<SEQ ID NO. 3805;RNA;Artificial Sequence> guugaaaugauagcagaau
<SEQ ID NO. 3806;RNA;Artificial Sequence> ugugcuucucucuggcagc
<SEQ ID NO. 3807;RNA;Artificial Sequence> cuggccuucugcuucugag
<SEQ ID NO. 3808;RNA;Artificial Sequence> guugcacauuaaucagauu
<SEQ ID NO. 3809;RNA;Artificial Sequence> uagecuguauucucuucag
<SEQ ID NO. 3810;RNA;Artificial Sequence> gugaauuuugauaauggcu
<SEQ ID NO. 3811;RNA;Artificial Sequence> uuccagacucuuuggcguu
<SEQ ID NO. 3812;RNA;Artificial Sequence> uggagacgccuguuaggau
<SEQ ID NO. 3813;RNA;Artificial Sequence> ucuucaagucccaucauag
<SEQ ID NO. 3814;RNA;Artificial Sequence> gaaaauugaaacacagagu
<SEQ ID NO. 3815;RNA;Artificial Sequence> uuguucugcugauaguuuu
<SEQ ID NO. 3816;RNA;Artificial Sequence> uggggauacguccaucuuu
<SEQ ID NO. 3817;RNA;Artificial Sequence> uuuaagggauugcuuucau
<SEQ ID NO. 3818;RNA;Artificial Sequence> ucuaauucuggcaggaccu
<SEQ ID NO. 3819;RNA;Artificial Sequence> ucaccaaaagauccagccu
<SEQ ID NO. 3820;RNA;Artificial Sequence> ucauaccuacaucagacaa
<SEQ ID NO. 3821;RNA;Artificial Sequence> aaauaucgccguuguuccu
<SEQ ID NO. 3822;RNA;Artificial Sequence> uucuguacuaaaguauugu
<SEQ ID NO. 3823;RNA;Artificial Sequence> uguuuugcuuuggaaacac
<SEQ ID NO. 3824;RNA;Artificial Sequence> cccacucacuuugcaauag
<SEQ ID NO. 3825;RNA;Artificial Sequence> gccgugcaagaugaaugca
<SEQ ID NO. 3826;RNA;Artificial Sequence> agauuacacugaucuuaug
<SEQ ID NO. 3827;RNA;Artificial Sequence> guguuacaaaauuggagaa
<SEQ ID NO. 3828;RNA;Artificial Sequence> aaguauuuaauaaaaccug
<SEQ ID NO. 3829;RNA;Artificial Sequence> guuaauuuuuauacugaca
<SEQ ID NO. 3830;RNA;Artificial Sequence> aauaaaaauguuucuacag
<SEQ ID NO. 3831;RNA;Artificial Sequence> gauauuaauguuaacaaga
<SEQ ID NO. 3832;RNA;Artificial Sequence> acaaaauaaaugucacgca
<SEQ ID NO. 3833;RNA;Artificial Sequence> ggcggcggcuggaggagagcgcggu
<SEQ ID NO. 3834;RNA;Artificial Sequence> uggagagccgagcgggcgggeggcg
<SEQ ID NO. 3835;RNA;Artificial Sequence> gggugcggagcgggcgagggagcgc
<SEQ ID NO. 3836;RNA;Artificial Sequence> cgcgcggccgccacaaagcucgggc
<SEQ ID NO. 3837;RNA;Artificial Sequence> cgccgcggggcugcaugcggcguac
<SEQ ID NO. 3838;RNA;Artificial Sequence> ccuggcccggcgcggcgacugcucu
<SEQ ID NO. 3839;RNA;Artificial Sequence> uccgggcuggcgggggccggccgcg
<SEQ ID NO. 3840;RNA;Artificial Sequence> gagccecgggggccccgaggccgca
<SEQ ID NO. 3841;RNA;Artificial Sequence> agcuugccugcgcgcucugagccuu
<SEQ ID NO. 3842;RNA;Artificial Sequence> ucgcaacucgcgagcaaaguuuggu
<SEQ ID NO. 3843;RNA;Artificial Sequence> uggaggcaacgccaagccugagucc
<SEQ ID NO. 3844;RNA;Artificial Sequence> cuuucuuccucucguuccccaaauc
<SEQ ID NO. 3845;RNA;Artificial Sequence> ccgagggcagcccgcgggcgucaug
<SEQ ID NO. 3846;RNA;Artificial Sequence> gcccgcgcuccuccgcagccugggg
<SEQ ID NO. 3847;RNA;Artificial Sequence> guacgcgugaagcccgggaggcuug
<SEQ ID NO. 3848;RNA;Artificial Sequence> ggcgccggegaagacccaaggacca
<SEQ ID NO. 3849;RNA;Artificial Sequence> acucuucugcguuuggaguugcucc
<SEQ ID NO. 3850;RNA;Artificial Sequence> cccgcaaccccgggcucgucgcuuu
<SEQ ID NO. 3851;RNA;Artificial Sequence> ucuccaucccgacccacgcggggcg
<SEQ ID NO. 3852;RNA;Artificial Sequence> gcggggacaacacaggucgcggagg
<SEQ ID NO. 3853;RNA;Artificial Sequence> gagcguugccauucaagugacugca
<SEQ ID NO. 3854;RNA;Artificial Sequence> agcagcagcggcagcgccucgguuc
<SEQ ID NO. 3855;RNA;Artificial Sequence> ccugagcccaccgcaggcugaaggc
<SEQ ID NO. 3856;RNA;Artificial Sequence> cauugcgcguaguccaugcccguag
<SEQ ID NO. 3857;RNA;Artificial Sequence> gaggaagugugcagaugggauuaac
<SEQ ID NO. 3858;RNA;Artificial Sequence> cguccacauggagauauggaagagg
<SEQ ID NO. 3859;RNA;Artificial Sequence> gaccggggauugguaccguaaccau
<SEQ ID NO. 3860;RNA;Artificial Sequence> uggucagcuggggucguuucaucug
<SEQ ID NO. 3861;RNA;Artificial Sequence> gccuggucguggucaccauggcaac
<SEQ ID NO. 3862;RNA;Artificial Sequence> ccuugucccuggcccggcccuccuu
<SEQ ID NO. 3863;RNA;Artificial Sequence> ucaguuuaguugaggauaccacauu
<SEQ ID NO. 3864;RNA;Artificial Sequence> uagagccagaagagccaccaaccaa
<SEQ ID NO. 3 865;RNA; Artificial Sequence> aauaccaaaucucucaaccagaagu
741-3730

CA 02677068 2009-09-01
<SEQ ID NO. 3866;RNA;Artificial Sequence> uguacguggcugcgccaggggaguc
<SEQ ID NO. 3867;RNA;Artificial Sequence> cgcuagaggugcgcugccuguugaa
<SEQ ID NO. 3868;RNA;Artificial Sequence> aagaugccgccgugaucaguuggac
<SEQ ID NO. 3869;RNA;Artificial Sequence> cuaaggauggggugcacuuggggcc
<SEQ ID NO. 3870;RNA;Artificial Sequence> ccaacaauaggacagugcuuauugg
<SEQ ID NO. 3871;RNA;Artificial Sequence> gggaguacuugcagauaaagggcgc
<SEQ ID NO. 3872;RNA;Artificial Sequence> ccacgccuagagacuccggccucua
<SEQ ID NO. 3873;RNA;Artificial Sequence> augcuuguacugccaguaggacugu
<SEQ ID NO. 3874;RNA;Artificial Sequence> uagacagugaaacuugguacuucau
<SEQ ID NO. 3875;RNA;Artificial Sequence> uggugaaugucacagaugccaucuc
<SEQ ID NO. 3876;RNA;Artificial Sequence> cauccggagaugaugaggaugacac
<SEQ ID NO. 3877;RNA;Artificial Sequence> ccgauggugcggaagauuuugucag
<SEQ ID NO. 3878;RNA;Artificial Sequence> gugagaacaguaacaacaagagagc
<SEQ ID NO. 3879;RNA;Artificial Sequence> caccauacuggaccaacacagaaaa
<SEQ ID NO. 3880;RNA;Artificial Sequence> agauggaaaagcggcuccaugcugu
<SEQ ID NO.3881;RNA;Artificial Sequence> ugccugcggccaacacugucaaguu
<SEQ ID NO. 3882;RNA;Artificial Sequence> uucgcugcccagccggggggaaccc
<SEQ ID NO. 3883;RNA;Artificial Sequence> caaugccaaccaugcgguggcugaa
<SEQ ID NO. 3884;RNA;Artificial Sequence> aaaacgggaaggaguuuaagcagga
<SEQ ID NO. 3885;RNA;Artificial Sequence> agcaucgcauuggaggcuacaaggu
<SEQ ID NO. 3886;RNA;Artificial Sequence> uacgaaaccagcacuggagccucau
<SEQ ID NO. 3887;RNA;Artificial Sequence> uuauggaaaguguggucccaucuga
<SEQ ID NO. 3888;RNA;Artificial Sequence> acaagggaaauuauaccuguguagu
<SEQ ID NO. 3889;RNA;Artificial Sequence> uggagaaugaauacggguccaucaa
<SEQ ID NO. 3890;RNA;Artificial Sequence> aucacacguaccaccuggauguugu
<SEQ ID NO. 3891;RNA;Artificial Sequence> uggagcgaucgccucaccggcccau
<SEQ ID NO. 3892;RNA;Artificial Sequence> uccuccaagccggacugccggcaaa
<SEQ ID NO. 3 893;RNA; Artificial Sequence> augccuccacaguggucggaggaga
<SEQ ID NO. 3894;RNA;Artificial Sequence> acguagaguuugucugcaagguuua
<SEQ ID NO. 3895;RNA;Artificial Sequence> acagugaugcccagccccacaucca
<SEQ ID NO. 3896;RNA;Artificial Sequence> aguggaucaagcacguggaaaagaa
<SEQ ID NO. 3897;RNA;Artificial Sequence> acggcaguaaauacgggcccgacgg
<SEQ ID NO. 3898;RNA;Artificial Sequence> ggcugcccuaccucaagguucucaa
<SEQ ID NO. 3899;RNA;Artificial Sequence> aggccgccgguguuaacaccacgga
<SEQ ID NO. 3900;RNA;Artificial Sequence> acaaagagauugagguucucuauau
<SEQ ID NO. 3901;RNA;Artificial Sequence> uucggaauguaacuuuugaggacgc
<SEQ ID NO. 3902;RNA; Artificial Sequence> cuggggaauauacgugcuuggcggg
<SEQ ID NO. 3903;RNA;Artificial Sequence> guaauucuauugggauauccuuuca
<SEQ ID NO. 3904;RNA;Artificial Sequence> acucugcaugguugacaguucugcc
<SEQ ID NO. 3905;RNA;Artificial Sequence> cagcgccuggaagagaaaaggagau
<SEQ ID NO. 3906;RNA;Artificial Sequence> uuacagcuuccccagacuaccugga
<SEQ ID NO. 3907;RNA;Artificial Sequence> agauagccauuuacugcauaggggu
<SEQ ID NO. 3908;RNA;Artificial Sequence> ucuucuuaaucgccuguaugguggu
<SEQ ID NO. 3909;RNA;Artificial Sequence> uaacagucauccugugccgaaugaa
<SEQ ID NO. 3910;RNA;Artificial Sequence> agaacacgaccaagaagccagacuu
<SEQ ID NO. 3911 ;RNA;Artificial Sequence> ucagcagccagccggcugugcacaa
<SEQ ID NO.3912;RNA;Artificial Sequence> agcugaccaaacguaucccccugcg
<SEQ ID NO. 3913;RNA;Artificial Sequence> ggagacagguaacaguuucggcuga
<SEQ ID NO. 3914;RNA;Artificial Sequence> aguccagcuccuccaugaacuccaa
<SEQ ID NO. 3915;RNA;Artificial Sequence> acaccccgcuggugaggauaacaac
<SEQ ID NO. 3916;RNA;Artificial Sequence> cacgccucucuucaacggcagacac
<SEQ ID NO. 3917;RNA;Artificial Sequence> cccccaugcuggcaggggucuccga
<SEQ ID NO. 3918;RNA;Artificial Sequence> aguaugaacuuccagaggacccaaa
<SEQ ID NO. 3919;RNA;Artificial Sequence> aaugggaguuuccaagagauaagcu
<SEQ ID NO. 3920;RNA;Artificial Sequence> ugacacugggcaagccccugggaga
<SEQ ID NO. 3921;RNA;Artificial Sequence> aagguugcuuugggcaaguggucau
<SEQ ID NO. 3922;RNA;Artificial Sequence> uggcggaagcagugggaauugacaa
<SEQ ID NO. 3923;RNA;Artificial Sequence> aagacaagcccaaggaggcggucac
<SEQ ID NO. 3924;RNA;Artificial Sequence> ccguggccgugaagauguugaaaga
<SEQ ID NO. 3925;RNA;Artificial Sequence> augaugccacagagaaagaccuuuc
<SEQ ID NO. 3926;RNA;Artificial Sequence> cugaucuggugucagagauggagau
<SEQ ID NO. 3927;RNA;Artificial Sequence> ugaugaagaugauugggaaacacaa
<SEQ ID NO. 3928;RNA;Artificial Sequence> agaauaucauaaaucuucuuggagc
<SEQ ID NO. 3929;RNA;Artificial Sequence> ccugcacacaggaugggccucucua
<SEQ ID NO. 3930;RNA;Artificial Sequence> augucauaguugaguaugccucuaa
<SEQ ID NO. 3931;RNA;Artificial Sequence> aaggcaaccuccgagaauaccuccg
<SEQ ID NO. 3932;RNA;Artificial Sequence> gagcccggaggccacccgggaugga
<SEQ ID NO. 3933;RNA;Artificial Sequence> aguacuccuaugacauuaaccgugu
<SEQ ID NO. 3934;RNA;Artificial Sequence> uuccugaggagcagaugaccuucaa
<SEQ ID NO. 3935;RNA;Artificial Sequence> aggacuuggugucaugcaccuacca
<SEQ ID NO. 3936;RNA;Artificial Sequence> agcuggccagaggcauggaguacuu
<SEQ ID NO. 3937;RNA;Artificial Sequence> uggcuucccaaaaauguauucaucg
<SEQ ID NO. 3938;RNA;Artificial Sequence> gagauuuagcagccagaaauguuuu
741-3731

CA 02677068 2009-09-01
<SEQ ID NO. 3939;RNA;Artificial Sequence> ugguaacagaaaacaaugugaugaa
<SEQ ID NO. 3940;RNA;Artificial Sequence> aaauagcagacuuuggacucgccag
<SEQ ID NO. 3941;RNA;Artificial Sequence> gagauaucaacaauauagacuauua
<SEQ ID NO. 3942;RNA;Artificial Sequence> acaaaaagaccaccaaugggcggcu
<SEQ ID NO. 3943;RNA;Artificial Sequence> uuccagucaaguggauggcuccaga
<SEQ ID NO. 3944;RNA;Artificial Sequence> aagcccuguuugauagaguauacac
<SEQ ID NO. 3945;RNA;Artificial Sequence> cucaucagagugaugucugguccuu
<SEQ ID NO. 3946;RNA;Artificial Sequence> ucgggguguuaaugugggagaucuu
<SEQ ID NO. 3947;RNA;Artificial Sequence> ucacuuuagggggcucgcccuaccc
<SEQ ID NO. 3948;RNA;Artificial Sequence> cagggauucccguggaggaacuuuu
<SEQ ID NO. 3949;RNA;Artificial Sequence> uuaagcugcugaaggaaggacacag
<SEQ ID NO. 3950;RNA;Artificial Sequence> gaauggauaagccagccaacugcac
<SEQ ID NO. 3951;RNA;Artificial Sequence> ccaacgaacuguacaugaugaugag
<SEQ ID NO. 3952;RNA;Artificial Sequence> gggacuguuggcaugcagugcccuc
<SEQ ID NO. 3953;RNA;Artificial Sequence> cccagagaccaacguucaagcaguu
<SEQ ID NO. 3954;RNA;Artificial Sequence> ugguagaagacuuggaucgaauucu
<SEQ ID NO. 3955;RNA;Artificial Sequence> ucacucucacaaccaaugaggaaua
<SEQ ID NO. 3956;RNA;Artificial Sequence> acuuggaccucagccaaccucucga
<SEQ ID NO. 3957;RNA;Artificial Sequence> aacaguauucaccuaguuacccuga
<SEQ ID NO. 3958;RNA;Artificial Sequence> acacaagaaguucuuguucuucagg
<SEQ ID NO. 3959;RNA;Artificial Sequence> gagaugauucuguuuuuucuccaga
<SEQ ID NO. 3960;RNA;Artificial Sequence> accccaugccuuacgaaccaugccu
<SEQ ID NO. 3961;RNA;Artificial Sequence> uuccucaguauccacacauaaacgg
<SEQ ID NO. 3962;RNA;Artificial Sequence> gcaguguuaaaacaugaaugacugu
<SEQ ID NO.3963;RNA;Artificial Sequence> ugucugccuguccccaaacaggaca
<SEQ ID NO. 3964;RNA;Artificial Sequence> agcacugggaaccuagcuacacuga
<SEQ ID NO. 3965;RNA;Artificial Sequence> agcagggagaccaugccucccagag
<SEQ ID NO. 3966;RNA;Artificial Sequence> gcuuguugucuccacuuguauauau
<SEQ ID NO. 3967;RNA;Artificial Sequence> uggaucagaggaguaaauaauugga
<SEQ ID NO. 3968;RNA;Artificial Sequence> aaaaguaaucagcauauguguaaag
<SEQ ID NO. 3969;RNA; Artificial Sequence> gauuuauacaguugaaaacuuguaa
<SEQ ID NO. 3970;RNA;Artificial Sequence> aucuuccccaggaggagaagaaggu
<SEQ ID NO. 3971;RNA;Artificial Sequence> uuucuggagcaguggacugccacaa
<SEQ ID NO. 3972;RNA;Artificial Sequence> agccaccauguaaccccucucaccu
<SEQ ID NO. 3973;RNA;Artificial Sequence> ugccgugcguacuggcuguggacca
<SEQ ID NO. 3974;RNA;Artificial Sequence> aguaggacucaagguggacgugcgu
<SEQ ID NO. 3975;RNA; Artificial Sequence> uucugccuuccuuguuaauuuugua
<SEQ ID NO. 3976;RNA;Artificial Sequence> aauaauuggagaagauuuaugucag
<SEQ ID NO. 3977;RNA;Artificial Sequence> gcacacacuuacagagcacaaaugc
<SEQ ID NO. 3978;RNA;Artificial Sequence> caguauauaggugcuggauguaugu
<SEQ ID NO. 3979;RNA;Artificial Sequence> uaaauauauucaaauuauguauaaa
<SEQ ID NO. 3980;RNA;Artificial Sequence> auauauauuauauauuuacaaggag
<SEQ ID NO. 3981;RNA;Artificial Sequence> guuauuuuuuguauugauuuuaaau
<SEQ ID NO. 3982;RNA;Artificial Sequence> uggaugucccaaugcaccuagaaaa
<SEQ ID NO. 3983;RNA;Artificial Sequence> auuggucucucuuuuuuuaauagcu
<SEQ ID NO. 3984;RNA;Artificial Sequence> uauuugcuaaaugcuguucuuacac
<SEQ ID NO. 3985;RNA;Artificial Sequence> cauaauuucuuaauuuucaccgagc
<SEQ ID NO. 3986;RNA;Artificial Sequence> cagagguggaaaaauacuuuugcuu
<SEQ ID NO. 3987;RNA;Artificial Sequence> uucagggaaaaugguauaacguuaa
<SEQ ID NO. 3988;RNA;Artificial Sequence> auuuauuaauaaauugguaauauac
<SEQ ID NO. 3989;RNA;Artificial Sequence> caaaacaauuaaucauuuauaguuu
<SEQ ID NO. 3990;RNA;Artificial Sequence> uuuuuuguaauuuaaguggcauuuc
<SEQ ID NO. 3991;RNA;Artificial Sequence> cuaugcaggcagcacagcagacuag
<SEQ ID NO. 3992;RNA;Artificial Sequence> guuaaucuauugcuuggacuuaacu
<SEQ ID NO. 3993;RNA;Artificial Sequence> uaguuaucagauccuuugaaaagag
<SEQ ID NO. 3994;RNA;Artificial Sequence> gaauauuuacaauauaugacuaauu
<SEQ ID NO. 3995;RNA;Artificial Sequence> uuggggaaaaugaaguuuugauuua
<SEQ ID NO. 3996;RNA;Artificial Sequence> auuuguguuuaaaugcugcugucag
<SEQ ID NO. 3997;RNA;Artificial Sequence> gacgauuguucuuagaccuccuaaa
<SEQ ID NO. 3998;RNA;Artificial Sequence> augccccauauuaaaagaacucauu
<SEQ ID NO. 3999;RNA;Artificial Sequence> ucauaggaagguguuucauuuuggu
<SEQ ID NO.4000;RNA;Artificial Sequence> ugugcaacccugucauuacgucaac
<SEQ ID NO. 4001;RNA;Artificial Sequence> cgcaacgucuaacuggacuucccaa
<SEQ ID NO.4002;RNA;Artificial Sequence> agauaaaugguaccagcguccucuu
<SEQ ID NO.4003;RNA;Artificial Sequence> uaaaagaugccuuaauccauuccuu
<SEQ ID NO. 4004;RNA; Artificial Sequence> ugaggacagaccuuaguugaaauga
<SEQ ID NO. 4005;RNA;Artificial Sequence> auagcagaaugugcuucucucuggc
<SEQ ID NO. 4006;RNA;Artificial Sequence> cagcuggccuucugcuucugaguug
<SEQ ID NO. 4007;RNA;Artificial Sequence> gcacauuaaucagauuagccuguau
<SEQ ID NO. 4008;RNA;Artificial Sequence> uucucuucagugaauuuugauaaug
<SEQ ID NO. 4009;RNA;Artificial Sequence> ggcuuccagacucuuuggcguugga
<SEQ ID NO.4010;RNA;Artificial Sequence> agacgccuguuaggaucuucaaguc
<SEQ ID NO. 401 1;RNA;Artificial Sequence> cccaucauagaaaauugaaacacag
741-3732

CA 02677068 2009-09-01
<SEQ ID NO. 4012;RNA;Artificial Sequence> gaguuguucugcugauaguuuuggg
<SEQ ID NO. 4013;RNA;Artificial Sequence> ggauacguccaucuuuuuaagggau
<SEQ ID NO. 4014;RNA;Artificial Sequence> uugcuuucaucuaauucuggcagga
<SEQ ID NO. 4015;RNA;Artificial Sequence> accucaccaaaagauccagccucau
<SEQ ID NO. 4016;RNA;Artificial Sequence> uaccuacaucagacaaaauaucgcc
<SEQ ID NO. 4017;RNA;Artificial Sequence> cguuguuccuucuguacuaaaguau
<SEQ ID NO. 4018;RNA;Artificial Sequence> uuguguuuugcuuuggaaacaccca
<SEQ ID NO. 4019;RNA;Artificial Sequence> acucacuuugcaauagccgugcaag
<SEQ ID NO. 4020;RNA;Artificial Sequence> gaugaaugcagauuacacugaucuu
<SEQ ID NO. 4021;RNA;Artificial Sequence> uauguguuacaaaauuggagaaagu
<SEQ ID NO. 4022;RNA;Artificial Sequence> uauuuaauaaaaccuguuaauuuuu
<SEQ ID NO. 4023;RNA;Artificial Sequence> uauacugacaauaaaaauguuucua
<SEQ ID NO. 4024;RNA;Artificial Sequence> acagauauuaauguuaacaagacaa
<SEQ ID NO. 4025;RNA;Artificial Sequence> aaauaaaugucacgcaacuuaaaaa
<SEQ ID NO. 4026;RNA;Artificial Sequence> agcacucggggauaaauaguuccaa
<SEQ ID NO. 4027;RNA;Artificial Sequence> augcagaagugcuggcucuguucaa
<SEQ ID NO. 4028;RNA;Artificial Sequence> augugaccgaggcggaugcugggga
<SEQ ID NO. 4029;RNA;Artificial Sequence> aauauauauguaaggucuccaauua
<SEQ ID NO. 4030;RNA;Artificial Sequence> auauagggcaggccaaccagucugc
<SEQ ID NO. 4031;RNA;Artificial Sequence> ccuggcucacuguccugccaaaaca
<SEQ ID NO. 4032;RNA;Artificial Sequence> agcaagcgccuggaagagaaaagga
<SEQ ID NO.4033;RNA;Artificial Sequence> agauuacagcuuccccagacuaccu
<SEQ ID NO. 4034;RNA;Artificial Sequence> uggagauagccauuuacugcauagg
<SEQ ID NO. 4035;RNA;Artificial Sequence> gggucuucuuaaucgccuguauggu
<SEQ ID NO. 4036;RNA;Artificial Sequence> ugguaacagucauccugugccgaau
<SEQ ID NO. 4037;RNA;Artificial Sequence> ugaagaacacgaccaagaagccaga
<SEQ ID NO. 4038;RNA;Artificial Sequence> acuucagcagccagccggcugugca
<SEQ ID NO. 4039;RNA;Artificial Sequence> acaagcugaccaaacguaucccccu
<SEQ ID NO. 4040;RNA;Artificial Sequence> ugcggagacagguaacaguuucggc
<SEQ ID NO. 4041;RNA;Artificial Sequence> cugaguccagcuccuccaugaacuc
<SEQ ID NO. 4042;RNA;Artificial Sequence> ccaacaccccgcuggugaggauaac
<SEQ ID NO. 4043;RNA;Artificial Sequence> caacacgccucucuucaacggcaga
<SEQ ID NO.4044;RNA;Artificial Sequence> acacccccaugcuggcaggggucuc
<SEQ ID NO. 4045;RNA;Artificial Sequence> ccgaguaugaacuuccagaggaccc
<SEQ ID NO. 4046;RNA;Artificial Sequence> caaaaugggaguuuccaagagauaa
<SEQ ID NO. 4047;RNA;Artificial Sequence> agcugacacugggcaagccccuggg
<SEQ ID NO. 4048;RNA;Artificial Sequence> gagaagguugcuuugggcaaguggu
<SEQ ID NO. 4049;RNA;Artificial Sequence> ucauggcggaagcagugggaauuga
<SEQ ID NO. 4050;RNA;Artificial Sequence> acaaagacaagcccaaggaggcggu
<SEQ ID NO. 4051;RNA;Artificial Sequence> ucaccguggccgugaagauguugaa
<SEQ ID NO. 4052;RNA;Artificial Sequence> aagaugaugccacagagaaagaccu
<SEQ ID NO. 4053;RNA;Artificial Sequence> uuucugaucuggugucagagaugga
<SEQ ID NO. 4054;RNA;Artificial Sequence> agaugaugaagaugauugggaaaca
<SEQ ID NO.4055;RNA;Artificial Sequence> acaagaauaucauaaaucuucuugg
<SEQ ID NO. 4056;RNA;Artificial Sequence> gagccugcacacaggaugggccucu
<SEQ ID NO. 4057;RNA;Artificial Sequence> ucuaugucauaguugaguaugccuc
<SEQ ID NO. 4058;RNA;Artificial Sequence> cuaaaggcaaccuccgagaauaccu
<SEQ ID NO. 4059;RNA;Artificial Sequence> uccgagcccggaggccacccgggau
<SEQ ID NO. 4060;RNA;Artificial Sequence> uggaguacuccuaugacauuaaccg
<SEQ ID NO. 4061;RNA;Artificial Sequence> guguuccugaggagcagaugaccuu
<SEQ ID NO. 4062;RNA;Artificial Sequence> ucaaggacuuggugucaugcaccua
<SEQ ID NO. 4063;RNA;Artificial Sequence> accagcuggccagaggcauggagua
<SEQ ID NO. 4064;RNA;Artificial Sequence> acuuggcuucccaaaaauguauuca
<SEQ ID NO. 4065;RNA;Artificial Sequence> aucgagauuuagcagccagaaaugu
<SEQ ID NO.4066;RNA;Artificial Sequence> uuuugguaacagaaaacaaugugau
<SEQ ID NO. 4067;RNA;Artificial Sequence> ugaaaauagcagacuuuggacucgc
<SEQ ID NO. 4068;RNA;Artificial Sequence> ccagagauaucaacaauauagacua
<SEQ ID NO. 4069;RNA;Artificial Sequence> auuacaaaaagaccaccaaugggcg
<SEQ ID NO. 4070;RNA;Artificial Sequence> ggcuuccagucaaguggauggcucc
<SEQ ID NO. 4071;RNA;Artificial Sequence> cagaagcccuguuugauagaguaua
<SEQ ID NO.4072;RNA;Artificial Sequence> acacucaucagagugaugucugguc
<SEQ ID NO. 4073;RNA;Artificial Sequence> ccuucgggguguuaaugugggagau
<SEQ ID NO. 4074;RNA;Artificial Sequence> ucuucacuuuagggggcucgcccua
<SEQ ID NO. 4075;RNA;Artificial Sequence> acccagggauucccguggaggaacu
<SEQ ID NO. 4076;RNA;Artificial Sequence> uuuuuaagcugcugaaggaaggaca
<SEQ ID NO. 4077;RNA;Artificial Sequence> acagaauggauaagccagccaacug
<SEQ ID NO.4078;RNA;Artificial Sequence> gcaccaacgaacuguacaugaugau
<SEQ ID NO. 4079;RNA;Artificial Sequence> ugagggacuguuggcaugcagugcc
<SEQ ID NO. 4080;RNA;Artificial Sequence> ccucccagagaccaacguucaagca
<SEQ ID NO. 4081;RNA;Artificial Sequence> aguugguagaagacuuggaucgaau
<SEQ ID NO. 4082;RNA;Artificial Sequence> uucucacucucacaaccaaugagga
<SEQ ID NO. 4083;RNA;Artificial Sequence> aauacuuggaccucagccaaccucu
<SEQ ID NO. 4084;RNA;Artificial Sequence> ucgaacaguauucaccuaguuaccc
741-3733

CA 02677068 2009-09-01
<SEQ ID NO. 4085;RNA;Artificial Sequence> cugacacaagaaguucuuguucuuc
<SEQ ID NO. 4086;RNA;Artificial Sequence> caggagaugauucuguuuuuucucc
<SEQ ID NO. 4087;RNA;Artificial Sequence> cagaccccaugccuuacgaaccaug
<SEQ ID NO. 4088;RNA;Artificial Sequence> gccuuccucaguauccacacauaaa
<SEQ ID NO. 4089;RNA;Artificial Sequence> acggcaguguuaaaacaugaaugac
<SEQ ID NO. 4090;RNA;Artificial Sequence> cugugucugccuguccccaaacagg
<SEQ ID NO. 4091;RNA;Artificial Sequence> gacagcacugggaaccuagcuacac
<SEQ ID NO. 4092;RNA;Artificial Sequence> cugagcagggagaccaugccuccca
<SEQ ID NO. 4093;RNA;Artificial Sequence> agagcuuguugucuccacuuguaua
<SEQ ID NO. 4094;RNA;Artificial Sequence> auauggaucagaggaguaaauaauu
<SEQ ID NO. 4095;RNA;Artificial Sequence> uggaaaaguaaucagcauaugugua
<SEQ ID NO. 4096;RNA;Artificial Sequence> aaagauuuauacaguugaaaacuug
<SEQ ID NO. 4097;RNA;Artificial Sequence> guaaucuuccccaggaggagaagaa
<SEQ ID NO. 4098;RNA;Artificial Sequence> agguuucuggagcaguggacugcca
<SEQ ID NO. 4099;RNA;Artificial Sequence> acaagccaccauguaaccccucuca
<SEQ ID NO. 4100;RNA;Artificial Sequence> accugccgugcguacuggcugugga
<SEQ ID NO. 4101;RNA;Artificial Sequence> accaguaggacucaagguggacgug
<SEQ ID NO. 4102;RNA;Artificial Sequence> gcguucugccuuccuuguuaauuuu
<SEQ ID NO. 4103;RNA;Artificial Sequence> uguaauaauuggagaagauuuaugu
<SEQ ID NO. 4104;RNA;Artificial Sequence> ucagcacacacuuacagagcacaaa
<SEQ ID NO. 4105;RNA;Artificial Sequence> augcaguauauaggugcuggaugua
<SEQ ID NO. 4106;RNA;Artificial Sequence> auguaaauauauucaaauuauguau
<SEQ ID NO. 4107;RNA;Artificial Sequence> uaaauauauauuauauauuuacaag
<SEQ ID NO. 4108;RNA;Artificial Sequence> ggaguuauuuuuuguauugauuuua
<SEQ ID NO. 4109;RNA;Artificial Sequence> aaauggaugucccaaugcaccuaga
<SEQ ID NO. 41 10;RNA;Artificial Sequence> aaaauuggucucucuuuuuuuaaua
<SEQ ID NO.4111;RNA;Artificial Sequence> agcuauuugcuaaaugcuguucuua
<SEQ ID NO. 4112;RNA;Artificial Sequence> acacauaauuucuuaauuuucaccg
<SEQ ID NO.4113;RNA;Artificial Sequence> gagcagagguggaaaaauacuuuug
<SEQ ID NO. 4114;RNA;Artificial Sequence> gcuuucagggaaaaugguauaacgu
<SEQ ID NO.4115;RNA;Artificial Sequence> uuaauuuauuaauaaauugguaaua
<SEQ ID NO. 4116;RNA;Artificial Sequence> auacaaaacaauuaaucauuuauag
<SEQ ID NO. 4117;RNA; Artificial Sequence> guuuuuuuuguaauuuaaguggcau
<SEQ ID NO. 4118;RNA; Artificial Sequence> uuucuaugcaggcagcacagcagac
<SEQ ID NO. 4119;RNA;Artificial Sequence> cuaguuaaucuauugcuuggacuua
<SEQ ID NO. 4120;RNA;Artificial Sequence> aacuaguuaucagauccuuugaaaa
<SEQ ID NO. 412 1;RNA;Artificial Sequence> agagaauauuuacaauauaugacua
<SEQ ID NO. 4122;RNA;Artificial Sequence> aauuuggggaaaaugaaguuuugau
<SEQ ID NO. 4123;RNA;Artificial Sequence> uuuauuuguguuuaaaugcugcugu
<SEQ ID NO. 4124;RNA;Artificial Sequence> ucagacgauuguucuuagaccuccu
<SEQ ID NO. 4125;RNA; Artificial Sequence> uaaaugccccauauuaaaagaacuc
<SEQ ID NO. 4126;RNA;Artificial Sequence> cauucauaggaagguguuucauuuu
<SEQ ID NO.4127;RNA;Artificial Sequence> uggugugcaacccugucauuacguc
<SEQ ID NO. 4128;RNA;Artificial Sequence> caacgcaacgucuaacuggacuucc
<SEQ ID NO. 4129;RNA;Artificial Sequence> ccaagauaaaugguaccagcguccu
<SEQ ID NO.4130;RNA;Artificial Sequence> ucuuaaaagaugccuuaauccauuc
<SEQ ID NO. 4131;RNA;Artificial Sequence> ccuugaggacagaccuuaguugaaa
<SEQ ID NO.4132;RNA;Artificial Sequence> augauagcagaaugugcuucucucu
<SEQ ID NO. 4133;RNA;Artificial Sequence> uggcagcuggccuucugcuucugag
<SEQ ID NO. 4134;RNA;Artificial Sequence> guugcacauuaaucagauuagccug
<SEQ ID NO. 4135;RNA;Artificial Sequence> guauucucuucagugaauuuugaua
<SEQ ID NO. 4136;RNA;Artificial Sequence> aauggcuuccagacucuuuggcguu
<SEQ ID NO.4137;RNA;Artificial Sequence> uggagacgccuguuaggaucuucaa
<SEQ ID NO. 4138;RNA; Artificial Sequence> agucccaucauagaaaauugaaaca
<SEQ ID NO. 4139;RNA;Artificial Sequence> acagaguuguucugcugauaguuuu
<SEQ ID NO. 4140;RNA;Artificial Sequence> uggggauacguccaucuuuuuaagg
<SEQ ID NO. 4141;RNA;Artificial Sequence> ggauugcuuucaucuaauucuggca
<SEQ ID NO. 4142;RNA;Artificial Sequence> aggaccucaccaaaagauccagccu
<SEQ ID NO. 4143;RNA;Artificial Sequence> ucauaccuacaucagacaaaauauc
<SEQ ID NO. 4144;RNA;Artificial Sequence> cgccguuguuccuucuguacuaaag
<SEQ ID NO. 4145;RNA;Artificial Sequence> guauuguguuuugcuuuggaaacac
<SEQ ID NO. 4146;RNA;Artificial Sequence> cccacucacuuugcaauagccgugc
<SEQ ID NO. 4147;RNA;Artificial Sequence> caagaugaaugcagauuacacugau
<SEQ ID NO. 4148;RNA;Artificial Sequence> ucuuauguguuacaaaauuggagaa
<SEQ ID NO. 4149;RNA;Artificial Sequence> aaguauuuaauaaaaccuguuaauu
<SEQ ID NO. 4150;RNA;Artificial Sequence> uuuuauacugacaauaaaaauguuu
<SEQ ID NO.4151;RNA;Artifcial Sequence> ucuacagauauuaauguuaacaaga
<SEQ ID NO. 4152;RNA;Artificial Sequence> acaaaauaaaugucacgcaacuuaa
<SEQ ID NO.4153;RNA;Homo sapiens>
CGCGCGCUGCCUGAGGACGCCGCGGCCCCCGCCCCCGCCAUGGGCGCCCCUGCCUGCGCCCUCGCGCUCUGC
GUGGCCGUGGCCAUCGUGGCCGGCGCCUCCUCGGAGUCCUUGGGGACGGAGCAGCGCGUCGUGGGGCGAGCGGCAGA
AGUCCCGGGCCCAGAGCCCGGCCAGCAGGAGCAGUUGGUCUUCGGCAGCGGGGAUGCUGUGGAGCUGAGCUGUCCCC
CGCCCGGGGGUGGUCCCAUGGGGCCCACUGUCUGGGUCAAGGAUGGCACAGGGCUGGUGCCCUCGGAGCGUGUCCUG
741-3734

CA 02677068 2009-09-01
GUGGGGCCCCAGCGGCUGCAGGUGCUGAAUGCCUCCCACGAGGACUCCGGGGCCUACAGCUGCCGGCAGCGGCUCAC
GCAGCGCGUACUGUGCCACUUCAGUGUGCGGGUGACAGACGCUCCAUCCUCGGGAGAUGACGAAGACGGGGAGGACG
AGGCUGAGGACACAGGUGUGGACACAGGGGCCCCUUACUGGACACGGCCCGAGCGGAUGGACAAGAAGCUGCUGGCC
GUGCCGGCCGCCAACACCGUCCGCUUCCGCUGCCCAGCCGCUGGCAACCCCACUCCCUCCAUCUCCUGGCUGAAGAAC
GGCAGGGAGUUCCGCGGCGAGCACCGCAUUGGAGGCAUCAAGCUGCGGCAUCAGCAGUGGAGCCUGGUCAUGGAAAG
CGUGGUGCCCUCGGACCGCGGCAACUACACCUGCGUCGUGGAGAACAAGUUUGGCAGCAUCCGGCAGACGUACACGC
UGGACGUGCUGGAGCGCUCCCCGCACCGGCCCAUCCUGCAGGCGGGGCUGCCGGCCAACCAGACGGCGGUGCUGGGC
AGCGACGUGGAGUUCCACUGCAAGGUGUACAGUGACGCACAGCCCCACAUCCAGUGGCUCAAGCACGUGGAGGUGAA
CGGCAGCAAGGUGGGCCCGGACGGCACACCCUACGUUACCGUGCUCAAGGUGUCCCUGGAGUCCAACGCGUCCAUGA
GCUCCAACACACCACUGGUGCGCAUCGCAAGGCUGUCCUCAGGGGAGGGCCCCACGCUGGCCAAUGUCUCCGAGCUC
GAGCUGCCUGCCGACCCCAAAUGGGAGCUGUCUCGGGCCCGGCUGACCCUGGGCAAGCCCCUUGGGGAGGGCUGCUU
CGGCCAGGUGGUCAUGGCGGAGGCCAUCGGCAUUGACAAGGACCGGGCCGCCAAGCCUGUCACCGUAGCCGUGAAGA
UGCUGAAAGACGAUGCCACUGACAAGGACCUGUCGGACCUGGUGUCUGAGAUGGAGAUGAUGAAGAUGAUCGGGAA
ACACAAAAACAUCAUCAACCUGCUGGGCGCCUGCACGCAGGGCGGGCCCCUGUACGUGCUGGUGGAGUACGCGGCCA
AGGGUAACCUGCGGGAGUUUCUGCGGGCGCGGCGGCCCCCGGGCCUGGACUACUCCUUCGACACCUGCAAGCCGCCC
GAGGAGCAGCUCACCUUCAAGGACCUGGUGUCCUGUGCCUACCAGGUGGCCCGGGGCAUGGAGUACUUGGCCUCCCA
GAAGUGCAUCCACAGGGACCUGGCUGCCCGCAAUGUGCUGGUGACCGAGGACAACGUGAUGAAGAUCGCAGACUUCG
GGCUGGCCCGGGACGUGCACAACCUCGACUACUACAAGAAGACAACCAACGGCCGGCUGCCCGUGAAGUGGAUGGCG
CCUGAGGCCUUGUUUGACCGAGUCUACACUCACCAGAGUGACGUCUGGUCCUUUGGGGUCCUGCUCUGGGAGAUCUU
CACGCUGGGGGGCUCCCCGUACCCCGGCAUCCCUGUGGAGGAGCUCUUCAAGCUGCUGAAGGAGGGCCACCGCAUGG
ACAAGCCCGCCAACUGCACACACGACCUGUACAUGAUCAUGCGGGAGUGCUGGCAUGCCGCGCCCUCCCAGAGGCCC
ACCUUCAAGCAGCUGGUGGAGGACCUGGACCGUGUCCUUACCGUGACGUCCACCGACGAGUACCUGGACCUGUCGGC
GCCUUUCGAGCAGUACUCCCCGGGUGGCCAGGACACCCCCAGCUCCAGCUCCUCAGGGGACGACUCCGUGUUUGCCCA
CGACCUGCUGCCCCCGGCCCCACCCAGCAGUGGGGGCUCGCGGACGUGAAGGGCCACUGGUCCCCAACAAUGUGAGG
GGUCCCUAGCAGCCCUCCCUGCUGCUGGUGCACAGCCACUCCCCGGCAUGAGACUCAGUGCAGAUGGAGAGACAGCU
ACACAGAGCUUUGGUCUGUGUGUGUGUGUGUGCGUGUGUGUGUGUGUGUGCACAUCCGCGUGUGCCUGUGUGCGUG
CGCAUCUUGCCUCCAGGUGCAGAGGUACCCUGGGUGUCCCCGCUGCUGUGCAACGGUCUCCUGACUGGUGCUGCAGC
ACCGAGGGGCCUUUGUUCUGGGGGGACCCAGUGCAGAAUGUAAGUGGGCCCACCCGGUGGGACCCCGUGGGGCAGGG
AGCUGGGCCCGACAUGGCUCGGCCUCUGCCUUUGCACCACGGGACAUCACAGGGUGCGCUCGGCCCCUCCCACACCCA
AAGCUGAGCCUGCAGGGAAGCCCCACAUGUCCAGCACCUUGUGCCUGGGGUGUUAGUGGCACCGCCUCCCCACCUCC
AGGCUUUCCCACUUCCCACCCUGCCCCUCAGAGACUGAAAUUACGGGUACCUGAAGAUGGGAGCCUUUACCUUUUAU
GCAAAAGGUUUAUUCCGGAAACUAGUGUACAUUUCUAUAAAUAGAUGCUGUGUAUAUGGUAUAUAUACAUAUAUAU
AUAUAACAUAUAUGGAAGAGGAAAAGGCUGGUACAACGGAGGCCUGCGACCCUGGGGGCACAGGAGGCAGGCAUGG
CCCUGGGCGGGGCGUGGGGGGGCGUGGAGGGAGGCCCCAGGGGUCUCACCCAUGCAAGCAGAGGACCAGGGCUUUUU
CUGGCACCGCAGUUUUGUUUUAAAACUGGACCUGUAUAUUUGUAAAGCUAUUUAUGGGCCCCUGGCACUCUUGUUCC
CACACCCCAACACUUCCAGCAUUUAGCUGGCCACAUGGCGGAGAGUUUUAAUUUUUAACUUAUUGACAACCGAGAAG
GUUUAUCCCGCCGAUAGAGGGACGGCCAAGAAUGUACGUCCAGCCUGCCCCGGAGCUGGAGGAUCCCCUCCAAGCCU
AAAAGGUUGUUAAUAGUUGGAGGUGAUUCCAGUGAAGAUAUUUUAUUUGCUUUGUCCUUUUUCAGGAGAAUUAGAU
UUCUAUAGGAUUUUUCUUUAGGAGAUUUAUUUUUUGGACUUCAAAGCAAGCUGGUAUUUUCAUACAAAUUCUUCUA
AUUGCUGUGUGUCCCAGGCAGGGAGACGGUUUCCAGGGAGGGGCCGGCCCUGUGUGCAGGUUCCGAUGUUAUUAGA
UGUUACAAGUUUAUAUAUAUCUAUAUAUAUAAUUUAUUGAGUUUUUACAAGAUGUAUUUGUUGUAGACUUAACACU
UCUUACGCAAUGCUUCUAGAGUUUUAUAGCCUGGACUGCUACCUUUCAAAGCUUGGAGGGAAGCCGUGAAUUCAGU
UGGUUCGUUCUGUACUGUUACUGGGCCCUGAGUCUGGGCAGCUGUCCCUUGCUUGCCUGCAGGGCCAUGGCUCAGGG
UGGUCUCUUCUUGGGGCCCAGUGCAUGGUGGCCAGAGGUGUCACCCAAACCGGCAGGUGCGAUUUUGUUAACCCAGC
GACGAACUUUCCGAAAAAUAAAGACACCUGGUUGCUAACCUGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 4154;RNA;Homo sapiens>
CGCGCGCUGCCUGAGGACGCCGCGGCCCCCGCCCCCGCCAUGGGCGCCCCUGCCUGCGCCCUCGCGCUCUGC
GUGGCCGUGGCCAUCGUGGCCGGCGCCUCCUCGGAGUCCUUGGGGACGGAGCAGCGCGUCGUGGGGCGAGCGGCAGA
AGUCCCGGGCCCAGAGCCCGGCCAGCAGGAGCAGUUGGUCUUCGGCAGCGGGGAUGCUGUGGAGCUGAGCUGUCCCC
CGCCCGGGGGUGGUCCCAUGGGGCCCACUGUCUGGGUCAAGGAUGGCACAGGGCUGGUGCCCUCGGAGCGUGUCCUG
GUGGGGCCCCAGCGGCUGCAGGUGCUGAAUGCCUCCCACGAGGACUCCGGGGCCUACAGCUGCCGGCAGCGGCUCAC
GCAGCGCGUACUGUGCCACUUCAGUGUGCGGGUGACAGACGCUCCAUCCUCGGGAGAUGACGAAGACGGGGAGGACG
AGGCUGAGGACACAGGUGUGGACACAGGGGCCCCUUACUGGACACGGCCCGAGCGGAUGGACAAGAAGCUGCUGGCC
GUGCCGGCCGCCAACACCGUCCGCUUCCGCUGCCCAGCCGCUGGCAACCCCACUCCCUCCAUCUCCUGGCUGAAGAAC
GGCAGGGAGUUCCGCGGCGAGCACCGCAUUGGAGGCAUCAAGCUGCGGCAUCAGCAGUGGAGCCUGGUCAUGGAAAG
CGUGGUGCCCUCGGACCGCGGCAACUACACCUGCGUCGUGGAGAACAAGUUUGGCAGCAUCCGGCAGACGUACACGC
UGGACGUGCUGGAGCGCUCCCCGCACCGGCCCAUCCUGCAGGCGGGGCUGCCGGCCAACCAGACGGCGGUGCUGGGC
AGCGACGUGGAGUUCCACUGCAAGGUGUACAGUGACGCACAGCCCCACAUCCAGUGGCUCAAGCACGUGGAGGUGAA
CGGCAGCAAGGUGGGCCCGGACGGCACACCCUACGUUACCGUGCUCAAGACGGCGGGCGCUAACACCACCGACAAGG
AGCUAGAGGUUCUCUCCUUGCACAACGUCACCUUUGAGGACGCCGGGGAGUACACCUGCCUGGCGGGCAAUUCUAUU
GGGUUUUCUCAUCACUCUGCGUGGCUGGUGGUGCUGCCAGCCGAGGAGGAGCUGGUGGAGGCUGACGAGGCGGGCA
GUGUGUAUGCAGGCAUCCUCAGCUACGGGGUGGGCUUCUUCCUGUUCAUCCUGGUGGUGGCGGCUGUGACGCUCUGC
CGCCUGCGCAGCCCCCCCAAGAAAGGCCUGGGCUCCCCCACCGUGCACAAGAUCUCCCGCUUCCCGCUCAAGCGACAG
GUGUCCCUGGAGUCCAACGCGUCCAUGAGCUCCAACACACCACUGGUGCGCAUCGCAAGGCUGUCCUCAGGGGAGGG
CCCCACGCUGGCCAAUGUCUCCGAGCUCGAGCUGCCUGCCGACCCCAAAUGGGAGCUGUCUCGGGCCCGGCUGACCCU
GGGCAAGCCCCUUGGGGAGGGCUGCUUCGGCCAGGUGGUCAUGGCGGAGGCCAUCGGCAUUGACAAGGACCGGGCCG
CCAAGCCUGUCACCGUAGCCGUGAAGAUGCUGAAAGACGAUGCCACUGACAAGGACCUGUCGGACCUGGUGUCUGAG
AUGGAGAUGAUGAAGAUGAUCGGGAAACACAAAAACAUCAUCAACCUGCUGGGCGCCUGCACGCAGGGCGGGCCCCU
GUACGUGCUGGUGGAGUACGCGGCCAAGGGUAACCUGCGGGAGUUUCUGCGGGCGCGGCGGCCCCCGGGCCUGGACU
ACUCCUUCGACACCUGCAAGCCGCCCGAGGAGCAGCUCACCUUCAAGGACCUGGUGUCCUGUGCCUACCAGGUGGCC
CGGGGCAUGGAGUACUUGGCCUCCCAGAAGUGCAUCCACAGGGACCUGGCUGCCCGCAAUGUGCUGGUGACCGAGGA
CAACGUGAUGAAGAUCGCAGACUUCGGGCUGGCCCGGGACGUGCACAACCUCGACUACUACAAGAAGACAACCAACG
GCCGGCUGCCCGUGAAGUGGAUGGCGCCUGAGGCCUUGUUUGACCGAGUCUACACUCACCAGAGUGACGUCUGGUCC
741-3735

CA 02677068 2009-09-01
UUUGGGGUCCUGCUCUGGGAGAUCUUCACGCUGGGGGGCUCCCCGUACCCCGGCAUCCCUGUGGAGGAGCUCUUCAA
GCUGCUGAAGGAGGGCCACCGCAUGGACAAGCCCGCCAACUGCACACACGACCUGUACAUGAUCAUGCGGGAGUGCU
GGCAUGCCGCGCCCUCCCAGAGGCCCACCUUCAAGCAGCUGGUGGAGGACCUGGACCGUGUCCUUACCGUGACGUCC
ACCGACGAGUACCUGGACCUGUCGGCGCCUUUCGAGCAGUACUCCCCGGGUGGCCAGGACACCCCCAGCUCCAGCUCC
UCAGGGGACGACUCCGUGUUUGCCCACGACCUGCUGCCCCCGGCCCCACCCAGCAGUGGGGGCUCGCGGACGUGAAG
GGCCACUGGUCCCCAACAAUGUGAGGGGUCCCUAGCAGCCCUCCCUGCUGCUGGUGCACAGCCACUCCCCGGCAUGA
GACUCAGUGCAGAUGGAGAGACAGCUACACAGAGCUUUGGUCUGUGUGUGUGUGUGUGCGUGUGUGUGUGUGUGUG
CACAUCCGCGUGUGCCUGUGUGCGUGCGCAUCUUGCCUCCAGGUGCAGAGGUACCCUGGGUGUCCCCGCUGCUGUGC
AACGGUCUCCUGACUGGUGCUGCAGCACCGAGGGGCCUUUGUUCUGGGGGGACCCAGUGCAGAAUGUAAGUGGGCCC
ACCCGGUGGGACCCCGUGGGGCAGGGAGCUGGGCCCGACAUGGCUCGGCCUCUGCCUUUGCACCACGGGACAUCACA
GGGUGCGCUCGGCCCCUCCCACACCCAAAGCUGAGCCUGCAGGGAAGCCCCACAUGUCCAGCACCUUGUGCCUGGGG
UGUUAGUGGCACCGCCUCCCCACCUCCAGGCUUUCCCACUUCCCACCCUGCCCCUCAGAGACUGAAAUUACGGGUACC
UGAAGAUGGGAGCCUUUACCUUUUAUGCAAAAGGUUUAUUCCGGAAACUAGUGUACAUUUCUAUAAAUAGAUGCUG
UGUAUAUGGUAUAUAUACAUAUAUAUAUAUAACAUAUAUGGAAGAGGAAAAGGCUGGUACAACGGAGGCCUGCGAC
CCUGGGGGCACAGGAGGCAGGCAUGGCCCUGGGCGGGGCGUGGGGGGGCGUGGAGGGAGGCCCCAGGGGUCUCACCC
AUGCAAGCAGAGGACCAGGGCUUUUUCUGGCACCGCAGUUUUGUUUUAAAACUGGACCUGUAUAUUUGUAAAGCUA
UUUAUGGGCCCCUGGCACUCUUGUUCCCACACCCCAACACUUCCAGCAUUUAGCUGGCCACAUGGCGGAGAGUUUUA
AUUUUUAACUUAUUGACAACCGAGAAGGUUUAUCCCGCCGAUAGAGGGACGGCCAAGAAUGUACGUCCAGCCUGCCC
CGGAGCUGGAGGAUCCCCUCCAAGCCUAAAAGGUUGUUAAUAGUUGGAGGUGAUUCCAGUGAAGAUAUUUUAUUUG
CUUUGUCCUUUUUCAGGAGAAUUAGAUUUCUAUAGGAUUUUUCUUUAGGAGAUUUAUUUUUUGGACUUCAAAGCAA
GCUGGUAUUUUCAUACAAAUUCUUCUAAUUGCUGUGUGUCCCAGGCAGGGAGACGGUUUCCAGGGAGGGGCCGGCCC
UGUGUGCAGGUUCCGAUGUUAUUAGAUGUUACAAGUUUAUAUAUAUCUAUAUAUAUAAUUUAUUGAGUUUUUACAA
GAUGUAUUUGUUGUAGACUUAACACUUCUUACGCAAUGCUUCUAGAGUUUUAUAGCCUGGACUGCUACCUUUCAAA
GCUUGGAGGGAAGCCGUGAAUUCAGUUGGUUCGUUCUGUACUGUUACUGGGCCCUGAGUCUGGGCAGCUGUCCCUU
GCUUGCCUGCAGGGCCAUGGCUCAGGGUGGUCUCUUCUUGGGGCCCAGUGCAUGGUGGCCAGAGGUGUCACCCAAAC
CGGCAGGUGCGAUUUUGUUAACCCAGCGACGAACUUUCCGAAAAAUAAAGACACCUGGUUGCUAACCUGAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 4155;RNA;Artificial Sequence> cgcgcgcugccugaggacg
<SEQ ID NO. 4156;RNA;Artificial Sequence> gccgcggcccccgcccccg
<SEQ ID NO. 4157;RNA;Artificial Sequence> gccaugggcgccccugccu
<SEQ ID NO. 4158;RNA;Artificial Sequence> ugcgcccucgcgcucugcg
<SEQ ID NO. 4159;RNA;Artificial Sequence> guggccguggccaucgugg
<SEQ ID NO. 4160;RNA;Artificial Sequence> gccggcgccuccucggagu
<SEQ ID NO.4161;RNA;Artificial Sequence> uccuuggggacggagcagc
<SEQ ID NO. 4162;RNA;Artificial Sequence> cgcgucguggggcgagcgg
<SEQ ID NO. 4163;RNA;Artificial Sequence> gcagaagucccgggcccag
<SEQ ID NO. 4164;RNA;Artificial Sequence> gagcccggccagcaggagc
<SEQ ID NO. 4165;RNA;Artificial Sequence> caguuggucuucggcagcg
<SEQ ID NO. 4166;RNA;Artificial Sequence> ggggaugcuguggagcuga
<SEQ ID NO. 4167;RNA;Artificial Sequence> agcugucccccgcccgggg
<SEQ ID NO. 4168;RNA;Artificial Sequence> gguggucccauggggccca
<SEQ ID NO. 4169;RNA;Artificial Sequence> acugucugggucaaggaug
<SEQ ID NO. 4170;RNA;Artificial Sequence> ggcacagggcuggugcccu
<SEQ ID NO. 4171;RNA;Artificial Sequence> ucggagcguguccuggugg
<SEQ ID NO. 4172;RNA;Artificial Sequence> gggccccagcggcugcagg
<SEQ ID NO. 4173;RNA;Artificial Sequence> gugcugaaugccucccacg
<SEQ ID NO. 4174;RNA;Artificial Sequence> gaggacuccggggccuaca
<SEQ ID NO. 4175;RNA;Artificial Sequence> agcugccggcagcggcuca
<SEQ ID NO. 4176;RNA;Artificial Sequence> acgcagcgcguacugugcc
<SEQ ID NO. 4177;RNA;Artificial Sequence> cacuucagugugcggguga
<SEQ ID NO. 4178;RNA;Artificial Sequence> acagacgcuccauccucgg
<SEQ ID NO. 4179;RNA;Artificial Sequence> ggagaugacgaagacgggg
<SEQ ID NO. 4180;RNA;Artificial Sequence> gaggacgaggcugaggaca
<SEQ ID NO. 4181;RNA;Artificial Sequence> acagguguggacacagggg
<SEQ ID NO. 4182;RNA;Artificial Sequence> gccccuuacuggacacggc
<SEQ ID NO. 4183;RNA;Artificial Sequence> cccgagcggauggacaaga
<SEQ ID NO. 4184;RNA;Artificial Sequence> aagcugcuggccgugccgg
<SEQ ID NO. 4185;RNA;Artificial Sequence> gccgccaacaccguccgcu
<SEQ ID NO. 4186;RNA;Artificial Sequence> uuccgcugcccagccgcug
<SEQ ID NO. 4187;RNA;Artificial Sequence> ggcaaccccacucccucca
<SEQ ID NO. 4188;RNA;Artificial Sequence> aucuccuggcugaagaacg
<SEQ ID NO. 4189;RNA;Artificial Sequence> ggcagggaguuccgcggcg
<SEQ ID NO. 4190;RNA;Artificial Sequence> gagcaccgcauuggaggca
<SEQ ID NO. 4191;RNA;Artificial Sequence> aucaagcugcggcaucagc
<SEQ ID NO. 4192;RNA;Artificial Sequence> caguggagccuggucaugg
<SEQ ID NO. 4193;RNA;Artificial Sequence> gaaagcguggugcccucgg
<SEQ ID NO. 4194;RNA;Artificial Sequence> gaccgcggcaacuacaccu
<SEQ ID NO. 4195;RNA;Artificial Sequence> ugcgucguggagaacaagu
<SEQ ID NO. 4196;RNA;Artificial Sequence> uuuggcagcauccggcaga
<SEQ ID NO. 4197;RNA;Artificial Sequence> acguacacgcuggacgugc
<SEQ ID NO. 4198;RNA;Artificial Sequence> cuggagcgcuccccgcacc
<SEQ ID NO. 4199;RNA;Artificial Sequence> cggcccauccugcaggcgg
<SEQ ID NO. 4200;RNA;Artificial Sequence> gggcugccggccaaccaga
741-3736

CA 02677068 2009-09-01
<SEQ ID NO. 4201;RNA;Artificial Sequence> acggcggugcugggcagcg
<SEQ ID NO. 4202;RNA;Artificial Sequence> gacguggaguuccacugca
<SEQ ID NO. 4203;RNA;Artificial Sequence> aagguguacagugacgcac
<SEQ ID NO. 4204;RNA;Artificial Sequence> cagccccacauccaguggc
<SEQ ID NO. 4205;RNA;Artificial Sequence> cucaagcacguggagguga
<SEQ ID NO. 4206;RNA;Artificial Sequence> aacggcagcaaggugggcc
<SEQ ID NO. 4207;RNA;Artificial Sequence> ccggacggcacacccuacg
<SEQ ID NO. 4208;RNA;Artificial Sequence> guuaccgugcucaagacgg
<SEQ ID NO.4209;RNA;Artificial Sequence> gcgggcgcuaacaccaccg
<SEQ ID NO. 4210;RNA;Artificial Sequence> gacaaggagcuagagguuc
<SEQ ID NO. 421 1;RNA;Artificial Sequence> cucuccuugcacaacguca
<SEQ ID NO.4212;RNA;Artificial Sequence> accuuugaggacgccgggg
<SEQ ID NO. 4213;RNA;Artificial Sequence> gaguacaccugccuggcgg
<SEQ ID NO. 4214;RNA;Artificial Sequence> ggcaauucuauuggguuuu
<SEQ ID NO. 4215;RNA;Artificial Sequence> ucucaucacucugcguggc
<SEQ ID NO. 4216;RNA;Artificial Sequence> cugguggugcugccagccg
<SEQ ID NO.4217;RNA;Artificial Sequence> gaggaggagcugguggagg
<SEQ ID NO. 4218;RNA;Artificial Sequence> gcugacgaggcgggcagug
<SEQ ID NO. 4219;RNA;Artificial Sequence> guguaugcaggcauccuca
<SEQ ID NO. 4220;RNA;Artificial Sequence> agcuacggggugggcuucu
<SEQ ID NO. 4221;RNA;Artificial Sequence> uuccuguucauccuggugg
<SEQ ID NO.4222;RNA;Artificial Sequence> guggcggcugugacgcucu
<SEQ ID NO. 4223;RNA;Artificial Sequence> ugccgccugcgcagccccc
<SEQ ID NO. 4224;RNA;Artificial Sequence> cccaagaaaggccugggcu
<SEQ ID NO. 4225;RNA;Artificial Sequence> ucccccaccgugcacaaga
<SEQ ID NO. 4226;RNA;Artificial Sequence> aucucccgcuucccgcuca
<SEQ ID NO. 4227;RNA;Artificial Sequence> aagcgacaggugucccugg
<SEQ ID NO. 4228;RNA;Artificial Sequence> gaguccaacgcguccauga
<SEQ ID NO. 4229;RNA;Artificial Sequence> agcuccaacacaccacugg
<SEQ ID NO. 4230;RNA;Artificial Sequence> gugcgcaucgcaaggcugu
<SEQ ID NO. 4231;RNA;Artificial Sequence> uccucaggggagggcccca
<SEQ ID NO. 4232;RNA;Artificial Sequence> acgcuggccaaugucuccg
<SEQ ID NO. 4233;RNA;Artificial Sequence> gagcucgagcugccugccg
<SEQ ID NO. 4234;RNA;Artificial Sequence> gaccccaaaugggagcugu
<SEQ ID NO.4235;RNA;Artificial Sequence> ucucgggcccggcugaccc
<SEQ ID NO.4236;RNA;Artificial Sequence> cugggcaagccccuugggg
<SEQ ID NO. 4237;RNA;Artificial Sequence> gagggcugcuucggccagg
<SEQ ID NO.4238;RNA;Artificial Sequence> guggucauggcggaggcca
<SEQ ID NO.4239;RNA;Artificial Sequence> aucggcauugacaaggacc
<SEQ ID NO. 4240;RNA;Artificial Sequence> cgggccgccaagccuguca
<SEQ ID NO. 4241;RNA;Artificial Sequence> accguagccgugaagaugc
<SEQ ID NO. 4242;RNA;Artificial Sequence> cugaaagacgaugccacug
<SEQ ID NO. 4243;RNA;Artificial Sequence> gacaaggaccugucggacc
<SEQ ID NO. 4244;RNA;Artificial Sequence> cuggugucugagauggaga
<SEQ ID NO. 4245;RNA;Artificial Sequence> aaacacaaaaacaucauca
<SEQ ID NO. 4246;RNA;Artificial Sequence> aaccugcugggcgccugca
<SEQ ID NO. 4247;RNA;Artificial Sequence> acgcagggcgggccccugu
<SEQ ID NO. 4248;RNA;Artificial Sequence> uacgugcugguggaguacg
<SEQ ID NO. 4249;RNA;Artificial Sequence> gcggccaaggguaaccugc
<SEQ ID NO. 4250;RNA;Artificial Sequence> cgggaguuucugcgggcgc
<SEQ ID NO. 4251;RNA;Artificial Sequence> cggcggcccccgggccugg
<SEQ ID NO.4252;RNA;Artificial Sequence> gacuacuccuucgacaccu
<SEQ ID NO. 4253;RNA;Artificial Sequence> ugcaagccgcccgaggagc
<SEQ ID NO. 4254;RNA;Artificial Sequence> cagcucaccuucaaggacc
<SEQ ID NO. 4255;RNA;Artificial Sequence> cugguguccugugccuacc
<SEQ ID NO. 4256;RNA;Artificial Sequence> cagguggcccggggcaugg
<SEQ ID NO.4257;RNA;Artiftcial Sequence> gaguacuuggccucccaga
<SEQ ID NO. 4258;RNA;Artificial Sequence> aagugcauccacagggacc
<SEQ ID NO. 4259;RNA;Artificial Sequence> cuggcugcccgcaaugugc
<SEQ ID NO. 4260;RNA;Artificial Sequence> cuggugaccgaggacaacg
<SEQ ID NO. 4261;RNA;Artificial Sequence> gugaugaagaucgcagacu
<SEQ ID NO. 4262;RNA;Artificial Sequence> uucgggcuggcccgggacg
<SEQ ID NO. 4263;RNA;Artificial Sequence> gugcacaaccucgacuacu
<SEQ ID NO. 4264;RNA;Artificial Sequence> uacaagaagacaaccaacg
<SEQ ID NO. 4265;RNA;Artificial Sequence> ggccggcugcccgugaagu
<SEQ ID NO. 4266;RNA;Artificial Sequence> uggauggcgccugaggccu
<SEQ ID NO. 4267;RNA;Artificial Sequence> uuguuugaccgagucuaca
<SEQ ID NO. 4268;RNA;Artificial Sequence> acucaccagagugacgucu
<SEQ ID NO. 4269;RNA;Artificial Sequence> ugguccuuugggguccugc
<SEQ ID NO. 4270;RNA;Artificial Sequence> cucugggagaucuucacgc
<SEQ ID NO.4271;RNA;Artificial Sequence> cuggggggcuccccguacc
<SEQ ID NO.4272;RNA;Artificial Sequence> cccggcaucccuguggagg
<SEQ ID NO.4273;RNA;Artificial Sequence> gagcucuucaagcugcuga
741-3737

CA 02677068 2009-09-01
<SEQ ID NO. 4274;RNA;Artificial Sequence> aaggagggccaccgcaugg
<SEQ ID NO. 4275;RNA;Artificial Sequence> gacaagcccgccaacugca
<SEQ ID NO. 4276;RNA;Artificial Sequence> acacacgaccuguacauga
<SEQ ID NO.4277;RNA;Artificial Sequence> aucaugcgggagugcuggc
<SEQ ID NO. 4278;RNA;Artificial Sequence> caugccgcgcccucccaga
<SEQ ID NO. 4279;RNA;Artificial Sequence> aggcccaccuucaagcagc
<SEQ ID NO. 4280;RNA;Artificial Sequence> cugguggaggaccuggacc
<SEQ ID NO. 4281;RNA;Artificial Sequence> cguguccuuaccgugacgu
<SEQ ID NO. 4282;RNA;Artificial Sequence> uccaccgacgaguaccugg
<SEQ ID NO. 4283;RNA;Artificial Sequence> gaccugucggcgccuuucg
<SEQ ID NO. 4284;RNA;Artificial Sequence> gagcaguacuccccgggug
<SEQ ID NO. 4285;RNA;Artificial Sequence> ggccaggacacccccagcu
<SEQ ID NO. 4286;RNA;Artificial Sequence> uccagcuccucaggggacg
<SEQ ID NO. 4287;RNA;Artificial Sequence> gacuccguguuugcccacg
<SEQ ID NO. 4288;RNA;Artificial Sequence> gaccugcugcccccggccc
<SEQ ID NO. 4289;RNA;Artificial Sequence> ccacccagcagugggggcu
<SEQ ID NO. 4290;RNA;Artificial Sequence> ucgcggacgugaagggcca
<SEQ ID NO.4291;RNA;Artificial Sequence> acugguccccaacaaugug
<SEQ ID NO. 4292;RNA;Artificial Sequence> gaggggucccuagcagccc
<SEQ ID NO. 4293;RNA;Artificial Sequence> cucccugcugcuggugcac
<SEQ ID NO. 4294;RNA;Artificial Sequence> cagccacuccccggcauga
<SEQ ID NO. 4295;RNA;Artificial Sequence> agacucagugcagauggag
<SEQ ID NO. 4296;RNA;Artificial Sequence> gagacagcuacacagagcu
<SEQ ID NO. 4297;RNA;Artificial Sequence> uuuggucugugugugugug
<SEQ ID NO. 4298;RNA;Artificial Sequence> gugugcgugugugugugug
<SEQ ID NO. 4299;RNA;Artificial Sequence> gugugcacauccgcgugug
<SEQ ID NO. 4300;RNA;Artificial Sequence> gccugugugcgugcgcauc
<SEQ ID NO. 4301 ;RNA;Artificial Sequence> cuugccuccaggugcagag
<SEQ ID NO. 4302;RNA;Artificial Sequence> gguacccuggguguccccg
<SEQ ID NO.4303;RNA;Artificial Sequence> gcugcugugcaacggucuc
<SEQ ID NO. 4304;RNA;Artificial Sequence> ccugacuggugcugcagca
<SEQ ID NO. 4305;RNA;Artificial Sequence> accgaggggccuuuguucu
<SEQ ID NO. 4306;RNA;Artificial Sequence> uggggggacccagugcaga
<SEQ ID NO. 4307;RNA;Artificial Sequence> aauguaagugggcccaccc
<SEQ ID NO. 4308;RNA; Artificial Sequence> cggugggaccccguggggc
<SEQ ID NO. 4309;RNA;Artificial Sequence> cagggagcugggcccgaca
<SEQ ID NO.4310;RNA;Artificial Sequence> auggcucggccucugccuu
<SEQ ID NO.4311;RNA;Artificial Sequence> uugcaccacgggacaucac
<SEQ ID NO. 4312;RNA;Artificial Sequence> cagggugcgcucggccccu
<SEQ ID NO. 4313;RNA;Artificial Sequence> ucccacacccaaagcugag
<SEQ ID NO. 4314;RNA;Artificial Sequence> gccugcagggaagccccac
<SEQ ID NO. 4315;RNA;Artificial Sequence> cauguccagcaccuugugc
<SEQ ID NO. 4316;RNA;Artificial Sequence> ccugggguguuaguggcac
<SEQ ID NO. 4317;RNA;Artificial Sequence> ccgccuccccaccuccagg
<SEQ ID NO.4318;RNA;Artificial Sequence> gcuuucccacuucccaccc
<SEQ ID NO. 4319;RNA;Artificial Sequence> cugccccucagagacugaa
<SEQ ID NO. 4320;RNA;Artificial Sequence> aauuacggguaccugaaga
<SEQ ID NO. 4321;RNA;Artificial Sequence> augggagccuuuaccuuuu
<SEQ ID NO. 4322;RNA;Artificial Sequence> uaugcaaaagguuuauucc
<SEQ ID NO. 4323;RNA;Artificial Sequence> cggaaacuaguguacauuu
<SEQ ID NO.4324;RNA;Artificial Sequence> ucuauaaauagaugcugug
<SEQ ID NO. 4325;RNA; Artificial Sequence> guauaugguauauauacau
<SEQ ID NO. 4326;RNA;Artificial Sequence> uauauauauauaacauaua
<SEQ ID NO. 4327;RNA;Artificial Sequence> auggaagaggaaaaggcug
<SEQ ID NO.4328;RNA;Artificial Sequence> gguacaacggaggccugcg
<SEQ ID NO. 4329;RNA;Artificial Sequence> gacccugggggcacaggag
<SEQ ID NO. 4330;RNA;Artificial Sequence> ggcaggcauggcccugggc
<SEQ ID NO. 4331;RNA;Artificial Sequence> cggggcgugggggggcgug
<SEQ ID NO. 4332;RNA; Artificial Sequence> ggagggaggccccaggggu
<SEQ ID NO. 4333;RNA;Artificial Sequence> ucucacccaugcaagcaga
<SEQ ID NO. 4334;RNA;Artificial Sequence> aggaccagggcuuuuucug
<SEQ ID NO. 4335;RNA;Artificial Sequence> ggcaccgcaguuuuguuuu
<SEQ ID NO.4336;RNA;Artiicial Sequence> uaaaacuggaccuguauau
<SEQ ID NO. 4337;RNA; Artificial Sequence> uuuguaaagcuauuuaugg
<SEQ ID NO.4338;RNA;Artificial Sequence> ggccccuggcacucuuguu
<SEQ ID NO. 4339;RNA;Artificial Sequence> ucccacaccccaacacuuc
<SEQ ID NO. 4340;RNA;Artificial Sequence> ccagcauuuagcuggccac
<SEQ ID NO. 4341;RNA;Artificial Sequence> cauggcggagaguuuuaau
<SEQ ID NO. 4342;RNA;Artificial Sequence> uuuuuaacuuauugacaac
<SEQ ID NO. 4343;RNA;Artificial Sequence> ccgagaagguuuaucccgc
<SEQ ID NO. 4344;RNA; Artificial Sequence> ccgauagagggacggccaa
<SEQ ID NO. 4345;RNA;Artificial Sequence> agaauguacguccagccug
<SEQ ID NO. 4346;RNA;Artificial Sequence> gccccggagcuggaggauc
741-3738

CA 02677068 2009-09-01
<SEQ ID NO. 4347;RNA;Artificial Sequence> ccccuccaagccuaaaagg
<SEQ ID NO. 4348;RNA;Artificial Sequence> guuguuaauaguuggaggu
<SEQ ID NO. 4349;RNA;Artificial Sequence> ugauuccagugaagauauu
<SEQ ID NO. 4350;RNA;Artificial Sequence> uuuauuugcuuuguccuuu
<SEQ ID NO. 4351;RNA;Artificial Sequence> uuucaggagaauuagauuu
<SEQ ID NO. 4352;RNA;Artificial Sequence> ucuauaggauuuuucuuua
<SEQ ID NO. 4353;RNA;Artificial Sequence> aggagauuuauuuuuugga
<SEQ ID NO. 4354;RNA;Artificial Sequence> acuucaaagcaagcuggua
<SEQ ID NO. 4355;RNA;Artificial Sequence> auuuucauacaaauucuuc
<SEQ ID NO. 4356;RNA; Artificial Sequence> cuaauugcuguguguccca
<SEQ ID NO. 4357;RNA;Artificial Sequence> aggcagggagacgguuucc
<SEQ ID NO. 4358;RNA;Artificial Sequence> cagggaggggccggcccug
<SEQ ID NO. 4359;RNA;Artificial Sequence> gugugcagguuccgauguu
<SEQ ID NO. 4360;RNA;Artificial Sequence> uauuagauguuacaaguuu
<SEQ ID NO. 4361;RNA;Artificial Sequence> uauauauaucuauauauau
<SEQ ID NO. 4362;RNA;Artificial Sequence> uaauuuauugaguuuuuac
<SEQ ID NO. 4363;RNA;Artificial Sequence> caagauguauuuguuguag
<SEQ ID NO. 4364;RNA;Artificial Sequence> gacuuaacacuucuuacgc
<SEQ ID NO. 4365;RNA;Artificial Sequence> caaugcuucuagaguuuua
<SEQ ID NO. 4366;RNA;Artificial Sequence> auagccuggacugcuaccu
<SEQ ID NO. 4367;RNA;Artificial Sequence> uuucaaagcuuggagggaa
<SEQ ID NO. 4368;RNA;Artificial Sequence> agccgugaauucaguuggu
<SEQ ID NO. 4369;RNA;Artificial Sequence> uucguucuguacuguuacu
<SEQ ID NO. 4370;RNA;Artificial Sequence> ugggcccugagucugggca
<SEQ ID NO. 4371;RNA;Artificial Sequence> agcugucccuugcuugccu
<SEQ ID NO. 4372;RNA;Artificial Sequence> ugcagggccauggcucagg
<SEQ ID NO. 4373;RNA;Artificial Sequence> gguggucucuucuuggggc
<SEQ ID NO. 4374;RNA;Artificial Sequence> cccagugcaugguggccag
<SEQ ID NO. 4375;RNA;Artificial Sequence> gaggugucacccaaaccgg
<SEQ ID NO. 4376;RNA;Artificial Sequence> gcaggugcgauuuuguuaa
<SEQ ID NO. 4377;RNA;Artificial Sequence> acccagcgacgaacuuucc
<SEQ ID NO. 4378;RNA;Artificial Sequence> cgaaaaauaaagacaccug
<SEQ ID NO. 4379;RNA;Artificial Sequence> gguugcuaaccugaaaaaa
<SEQ ID NO. 4380;RNA;Artificial Sequence> guuaccgugcucaaggugu
<SEQ ID NO.4381;RNA;Artificial Sequence> ucccuggaguccaacgcgu
<SEQ ID NO. 4382;RNA;Artificial Sequence> uccaugagcuccaacacac
<SEQ ID NO. 4383;RNA;Artificial Sequence> ccacuggugcgcaucgcaa
<SEQ ID NO. 4384;RNA;Artificial Sequence> aggcuguccucaggggagg
<SEQ ID NO.4385;RNA;Artificial Sequence> ggccccacgcuggccaaug
<SEQ ID NO. 4386;RNA;Artificial Sequence> gucuccgagcucgagcugc
<SEQ ID NO. 4387;RNA;Artificial Sequence> ccugccgaccccaaauggg
<SEQ ID NO. 4388;RNA;Artificial Sequence> gagcugucucgggcccggc
<SEQ ID NO. 4389;RNA;Artificial Sequence> cugacccugggcaagcccc
<SEQ ID NO.4390;RNA;Artificial Sequence> cuuggggagggcugcuucg
<SEQ ID NO. 4391;RNA;Artificial Sequence> ggccagguggucauggcgg
<SEQ ID NO. 4392;RNA;Artificial Sequence> gaggccaucggcauugaca
<SEQ ID NO. 4393;RNA;Artificial Sequence> aaggaccgggccgccaagc
<SEQ ID NO. 4394;RNA;Artificial Sequence> ccugucaccguagccguga
<SEQ ID NO. 4395;RNA; Artificial Sequence> aagaugcugaaagacgaug
<SEQ ID NO. 4396;RNA;Artificial Sequence> gccacugacaaggaccugu
<SEQ ID NO.4397;RNA;Artificial Sequence> ucggaccuggugucugaga
<SEQ ID NO. 4398;RNA;Artificial Sequence> aucgggaaacacaaaaaca
<SEQ ID NO. 4399;RNA;Artificial Sequence> aucaucaaccugcugggcg
<SEQ ID NO. 4400;RNA;Artificial Sequence> gccugcacgcagggcgggc
<SEQ ID NO. 4401;RNA;Artificial Sequence> ccccuguacgugcuggugg
<SEQ ID NO.4402;RNA;Artificial Sequence> gaguacgcggccaagggua
<SEQ ID NO. 4403;RNA;Artificial Sequence> aaccugcgggaguuucugc
<SEQ ID NO. 4404;RNA;Artificial Sequence> cgggcgcggcggcccccgg
<SEQ ID NO. 4405;RNA;Artificial Sequence> ggccuggacuacuccuucg
<SEQ ID NO. 4406;RNA;Artificial Sequence> gacaccugcaagccgcccg
<SEQ ID NO. 4407;RNA;Artificial Sequence> gaggagcagcucaccuuca
<SEQ ID NO. 4408;RNA;Artificial Sequence> aaggaccugguguccugug
<SEQ ID NO. 4409;RNA;Artificial Sequence> gccuaccagguggcccggg
<SEQ ID NO. 4410;RNA;Artificial Sequence> ggcauggaguacuuggccu
<SEQ ID NO.4411;RNA;Artificial Sequence> ucccagaagugcauccaca
<SEQ ID NO. 4412;RNA;Artificial Sequence> agggaccuggcugcccgca
<SEQ ID NO. 4413;RNA;Artificial Sequence> aaugugcuggugaccgagg
<SEQ ID NO.4414;RNA;Artificial Sequence> gacaacgugaugaagaucg
<SEQ ID NO. 4415;RNA;Artificial Sequence> gcagacuucgggcuggccc
<SEQ ID NO. 4416;RNA;Artificial Sequence> cgggacgugcacaaccucg
<SEQ ID NO. 4417;RNA;Artificial Sequence> gacuacuacaagaagacaa
<SEQ ID NO.4418;RNA;Artificial Sequence> accaacggccggcugcccg
<SEQ ID NO. 4419;RNA;Artificial Sequence> gugaaguggauggcgccug
741-3739

CA 02677068 2009-09-01
<SEQ ID NO. 4420;RNA;Artificial Sequence> gaggccuuguuugaccgag
<SEQ ID NO. 4421;RNA;Artificial Sequence> gucuacacucaccagagug
<SEQ ID NO. 4422;RNA;Artificial Sequence> gacgucugguccuuugggg
<SEQ ID NO. 4423;RNA;Artificial Sequence> guccugcucugggagaucu
<SEQ ID NO. 4424;RNA;Artificial Sequence> uucacgcuggggggcuccc
<SEQ ID NO. 4425;RNA;Artificial Sequence> ccguaccccggcaucccug
<SEQ ID NO. 4426;RNA;Artificial Sequence> guggaggagcucuucaagc
<SEQ ID NO. 4427;RNA;Artificial Sequence> cugcugaaggagggccacc
<SEQ ID NO.4428;RNA;Artificial Sequence> cgcauggacaagcccgcca
<SEQ ID NO. 4429;RNA;Artificial Sequence> aacugcacacacgaccugu
<SEQ ID NO. 4430;RNA;Artificial Sequence> uacaugaucaugcgggagu
<SEQ ID NO. 4431;RNA;Artificial Sequence> ugcuggcaugccgcgcccu
<SEQ ID NO. 4432;RNA;Artificial Sequence> ucccagaggcccaccuuca
<SEQ ID NO.4433;RNA;Artificial Sequence> aagcagcugguggaggacc
<SEQ ID NO. 4434;RNA;Artificial Sequence> cuggaccguguccuuaccg
<SEQ ID NO. 4435;RNA;Artificial Sequence> gugacguccaccgacgagu
<SEQ ID NO. 4436;RNA;Artificial Sequence> uaccuggaccugucggcgc
<SEQ ID NO.4437;RNA;Artificial Sequence> ccuuucgagcaguacuccc
<SEQ ID NO. 4438;RNA;Artificial Sequence> ccggguggccaggacaccc
<SEQ ID NO. 4439;RNA;Artificial Sequence> cccagcuccagcuccucag
<SEQ ID NO. 4440;RNA;Artificial Sequence> ggggacgacuccguguuug
<SEQ ID NO. 4441;RNA;Artificial Sequence> gcccacgaccugcugcccc
<SEQ ID NO. 4442;RNA;Artificial Sequence> ccggccccacccagcagug
<SEQ ID NO. 4443;RNA;Artificial Sequence> gggggcucgcggacgugaa
<SEQ ID NO. 4444;RNA;Artificial Sequence> agggccacugguccccaac
<SEQ ID NO. 4445;RNA;Artificial Sequence> caaugugaggggucccuag
<SEQ ID NO. 4446;RNA;Artificial Sequence> gcagcccucccugcugcug
<SEQ ID NO.4447;RNA;Artificial Sequence> ggugcacagccacuccccg
<SEQ ID NO. 4448;RNA;Artificial Sequence> ggcaugagacucagugcag
<SEQ ID NO. 4449;RNA;Artificial Sequence> gauggagagacagcuacac
<SEQ ID NO. 4450;RNA; Artificial Sequence> cagagcuuuggucugugug
<SEQ ID NO.4451;RNA;Artificial Sequence> gugugugugugcgugugug
<SEQ ID NO. 4452;RNA;Artificial Sequence> gugugugugugcacauccg
<SEQ ID NO. 4453;RNA;Artificial Sequence> gcgugugccugugugcgug
<SEQ ID NO. 4454;RNA;Artificial Sequence> gcgcaucuugccuccaggu
<SEQ ID NO. 4455;RNA;Artificial Sequence> ugcagagguacccugggug
<SEQ ID NO. 4456;RNA; Artificial Sequence> guccccgcugcugugcaac
<SEQ ID NO. 4457;RNA;Artificial Sequence> cggucuccugacuggugcu
<SEQ ID NO. 4458;RNA;Artificial Sequence> ugcagcaccgaggggccuu
<SEQ ID NO. 4459;RNA;Artificial Sequence> uuguucuggggggacccag
<SEQ ID NO. 4460;RNA;Artificial Sequence> gugcagaauguaagugggc
<SEQ ID NO. 4461;RNA;Artificial Sequence> cccacccggugggaccccg
<SEQ ID NO. 4462;RNA;Artificial Sequence> guggggcagggagcugggc
<SEQ ID NO. 4463;RNA;Artificial Sequence> cccgacauggcucggccuc
<SEQ ID NO. 4464;RNA;Artificial Sequence> cugccuuugcaccacggga
<SEQ ID NO. 4465;RNA;Artificial Sequence> acaucacagggugcgcucg
<SEQ ID NO. 4466;RNA;Artificial Sequence> ggccccucccacacccaaa
<SEQ ID NO. 4467;RNA;Artificial Sequence> agcugagccugcagggaag
<SEQ ID NO. 4468;RNA;Artificial Sequence> gccccacauguccagcacc
<SEQ ID NO.4469;RNA;Artificial Sequence> cuugugccugggguguuag
<SEQ ID NO.4470;RNA;Artificial Sequence> guggcaccgccuccccacc
<SEQ ID NO. 447 1;RNA;Artificial Sequence> cuccaggcuuucccacuuc
<SEQ ID NO. 4472;RNA;Artificial Sequence> cccacccugccccucagag
<SEQ ID NO. 4473;RNA;Artificial Sequence> gacugaaauuacggguacc
<SEQ ID NO. 4474;RNA;Artificial Sequence> cugaagaugggagccuuua
<SEQ ID NO. 4475;RNA;Artificial Sequence> accuuuuaugcaaaagguu
<SEQ ID NO. 4476;RNA;Artificial Sequence> uuauuccggaaacuagugu
<SEQ ID NO.4477;RNA;Artificial Sequence> uacauuucuauaaauagau
<SEQ ID NO. 4478;RNA;Artificial Sequence> ugcuguguauaugguauau
<SEQ ID NO. 4479;RNA;Artificial Sequence> uauacauauauauauauaa
<SEQ ID NO. 4480;RNA;Artificial Sequence> acauauauggaagaggaaa
<SEQ ID NO.4481;RNA;Artificial Sequence> aaggcugguacaacggagg
<SEQ ID NO.4482;RNA;Artificial Sequence> gccugcgacccugggggca
<SEQ ID NO.4483;RNA;Artificial Sequence> acaggaggcaggcauggcc
<SEQ ID NO. 4484;RNA;Artificial Sequence> ccugggcggggcguggggg
<SEQ ID NO. 4485;RNA;Artificial Sequence> gggcguggagggaggcccc
<SEQ ID NO. 4486;RNA;Artificial Sequence> caggggucucacccaugca
<SEQ ID NO. 4487;RNA;Artificial Sequence> aagcagaggaccagggcuu
<SEQ ID NO. 4488;RNA;Artificial Sequence> uuuucuggcaccgcaguuu
<SEQ ID NO. 4489;RNA;Artificial Sequence> uuguuuuaaaacuggaccu
<SEQ ID NO. 4490;RNA;Artificial Sequence> uguauauuuguaaagcuau
<SEQ ID NO. 4491;RNA;Artificial Sequence> uuuaugggccccuggcacu
<SEQ ID NO.4492;RNA;Artificial Sequence> ucuuguucccacaccccaa
741-3740

CA 02677068 2009-09-01
<SEQ ID NO. 4493;RNA;Artificial Sequence> acacuuccagcauuuagcu
<SEQ ID NO. 4494;RNA;Artificial Sequence> uggccacauggcggagagu
<SEQ ID NO. 4495;RNA;Artificial Sequence> uuuuaauuuuuaacuuauu
<SEQ ID NO. 4496;RNA;Artificial Sequence> ugacaaccgagaagguuua
<SEQ ID NO. 4497;RNA;Artificial Sequence> aucccgccgauagagggac
<SEQ ID NO. 4498;RNA;Artificial Sequence> cggccaagaauguacgucc
<SEQ ID NO. 4499;RNA;Artificial Sequence> cagccugccccggagcugg
<SEQ ID NO. 4500;RNA;Artificial Sequence> gaggauccccuccaagccu
<SEQ ID NO.4501;RNA;Artificial Sequence> uaaaagguuguuaauaguu
<SEQ ID NO. 4502;RNA;Artificial Sequence> uggaggugauuccagugaa
<SEQ ID NO. 4503;RNA;Artificial Sequence> agauauuuuauuugcuuug
<SEQ ID NO. 4504;RNA;Artificial Sequence> guccuuuuucaggagaauu
<SEQ ID NO.4505;RNA;Artificial Sequence> uagauuucuauaggauuuu
<SEQ ID NO. 4506;RNA;Artificial Sequence> uucuuuaggagauuuauuu
<SEQ ID NO. 4507;RNA;Artificial Sequence> uuuuggacuucaaagcaag
<SEQ ID NO. 4508;RNA;Artificial Sequence> gcugguauuuucauacaaa
<SEQ ID NO.4509;RNA;Artificial Sequence> auucuucuaauugcugugu
<SEQ ID NO. 4510;RNA;Artificial Sequence> ugucccaggcagggagacg
<SEQ ID NO.4511;RNA;Artificial Sequence> gguuuccagggaggggccg
<SEQ ID NO. 4512;RNA;Artificial Sequence> ggcccugugugcagguucc
<SEQ ID NO. 4513;RNA;Artificial Sequence> cgauguuauuagauguuac
<SEQ ID NO. 4514;RNA;Artificial Sequence> caaguuuauauauaucuau
<SEQ ID NO. 4515;RNA;Artificial Sequence> uauauauaauuuauugagu
<SEQ ID NO.4516;RNA;Artificial Sequence> uuuuuacaagauguauuug
<SEQ ID NO. 4517;RNA;Artificial Sequence> guuguagacuuaacacuuc
<SEQ ID NO. 4518;RNA;Artificial Sequence> cuuacgcaaugcuucuaga
<SEQ ID NO. 4519;RNA;Artificial Sequence> aguuuuauagccuggacug
<SEQ ID NO. 4520;RNA;Artificial Sequence> gcuaccuuucaaagcuugg
<SEQ ID NO. 4521;RNA;Artificial Sequence> gagggaagccgugaauuca
<SEQ ID NO.4522;RNA;Artificial Sequence> aguugguucguucuguacu
<SEQ ID NO.4523;RNA;Artificial Sequence> uguuacugggcccugaguc
<SEQ ID NO. 4524;RNA;Artificial Sequence> cugggcagcugucccuugc
<SEQ ID NO. 4525;RNA;Artificial Sequence> cuugccugcagggccaugg
<SEQ ID NO. 4526;RNA;Artificial Sequence> gcucaggguggucucuucu
<SEQ ID NO. 4527;RNA;Artificial Sequence> uuggggcccagugcauggu
<SEQ ID NO.4528;RNA;Artificial Sequence> uggccagaggugucaccca
<SEQ ID NO. 4529;RNA;Artificial Sequence> aaaccggcaggugcgauuu
<SEQ ID NO. 4530;RNA;Artificial Sequence> uuguuaacccagcgacgaa
<SEQ ID NO. 4531;RNA;Artificial Sequence> acuuuccgaaaaauaaaga
<SEQ ID NO.4532;RNA;Artificial Sequence> acaccugguugcuaaccug
<SEQ ID NO. 4533;RNA; Artificial Sequence> cgcgcgcugccugaggacgccgcgg
<SEQ ID NO. 4534;RNA;Artificial Sequence> gcccccgcccccgccaugggcgccc
<SEQ ID NO. 4535;RNA;Artificial Sequence> ccugccugcgcccucgcgcucugcg
<SEQ ID NO.4536;RNA;Artificial Sequence> guggccguggccaucguggccggcg
<SEQ ID NO. 4537;RNA;Artificial Sequence> gccuccucggaguccuuggggacgg
<SEQ ID NO. 4538;RNA;Artificial Sequence> gagcagcgcgucguggggcgagcgg
<SEQ ID NO. 4539;RNA;Artificial Sequence> gcagaagucccgggcccagagcccg
<SEQ ID NO. 4540;RNA;Artificial Sequence> ggccagcaggagcaguuggucuucg
<SEQ ID NO. 4541;RNA;Artificial Sequence> ggcagcggggaugcuguggagcuga
<SEQ ID NO. 4542;RNA;Artificial Sequence> agcugucccccgcccgggggugguc
<SEQ ID NO. 4543;RNA;Artificial Sequence> cccauggggcccacugucuggguca
<SEQ ID NO. 4544;RNA;Artificial Sequence> aaggauggcacagggcuggugcccu
<SEQ ID NO. 4545;RNA;Artificial Sequence> ucggagcguguccugguggggcccc
<SEQ ID NO.4546;RNA;Artificial Sequence> cagcggcugcaggugcugaaugccu
<SEQ ID NO. 4547;RNA;Artificial Sequence> ucccacgaggacuccggggccuaca
<SEQ ID NO. 4548;RNA;Artificial Sequence> agcugccggcagcggcucacgcagc
<SEQ ID NO.4549;RNA;Artificial Sequence> cgcguacugugccacuucagugugc
<SEQ ID NO. 4550;RNA;Artificial Sequence> cgggugacagacgcuccauccucgg
<SEQ ID NO. 4551;RNA;Artificial Sequence> ggagaugacgaagacggggaggacg
<SEQ ID NO. 4552;RNA;Artificial Sequence> gaggcugaggacacagguguggaca
<SEQ ID NO. 4553;RNA;Artificial Sequence> acaggggccccuuacuggacacggc
<SEQ ID NO.4554;RNA;Artificial Sequence> cccgagcggauggacaagaagcugc
<SEQ ID NO. 4555;RNA;Artificial Sequence> cuggccgugccggccgccaacaccg
<SEQ ID NO. 4556;RNA;Artificial Sequence> guccgcuuccgcugcccagccgcug
<SEQ ID NO. 4557;RNA;Artificial Sequence> ggcaaccccacucccuccaucuccu
<SEQ ID NO.4558;RNA;Artificial Sequence> uggcugaagaacggcagggaguucc
<SEQ ID NO. 4559;RNA;Artificial Sequence> cgcggcgagcaccgcauuggaggca
<SEQ ID NO. 4560;RNA;Artificial Sequence> aucaagcugcggcaucagcagugga
<SEQ ID NO. 4561;RNA;Artificial Sequence> agccuggucauggaaagcguggugc
<SEQ ID NO. 4562;RNA;Artificial Sequence> cccucggaccgcggcaacuacaccu
<SEQ ID NO. 4563;RNA;Artificial Sequence> ugcgucguggagaacaaguuuggca
<SEQ ID NO. 4564;RNA;Artificial Sequence> agcauccggcagacguacacgcugg
<SEQ ID NO.4565;RNA;Artificial Sequence> gacgugcuggagcgcuccccgcacc
741-3741

CA 02677068 2009-09-01
<SEQ ID NO. 4566;RNA;Artificial Sequence> cggcccauccugcaggcggggcugc
<SEQ ID NO.4567;RNA;Artificial Sequence> ccggccaaccagacggcggugcugg
<SEQ ID NO. 4568;RNA;Artificial Sequence> ggcagcgacguggaguuccacugca
<SEQ ID NO. 4569;RNA;Artificial Sequence> aagguguacagugacgcacagcccc
<SEQ ID NO. 4570;RNA;Artificial Sequence> cacauccaguggcucaagcacgugg
<SEQ ID NO. 4571;RNA;Artificial Sequence> gaggugaacggcagcaaggugggcc
<SEQ ID NO. 4572;RNA;Artificial Sequence> ccggacggcacacccuacguuaccg
<SEQ ID NO. 4573;RNA; Artificial Sequence> gugcucaagacggcgggcgcuaaca
<SEQ ID NO. 4574;RNA;Artificial Sequence> accaccgacaaggagcuagagguuc
<SEQ ID NO.4575;RNA;Artificial Sequence> cucuccuugcacaacgucaccuuug
<SEQ ID NO. 4576;RNA;Artificial Sequence> gaggacgccggggaguacaccugcc
<SEQ ID NO. 4577;RNA;Artificial Sequence> cuggcgggcaauucuauuggguuuu
<SEQ ID NO. 4578;RNA;Artificial Sequence> ucucaucacucugcguggcuggugg
<SEQ ID NO. 4579;RNA;Artificial Sequence> gugcugccagccgaggaggagcugg
<SEQ ID NO. 45 80;RNA; Artificial Sequence> guggaggcugacgaggcgggcagug
<SEQ ID NO. 458 1;RNA;Artificial Sequence> guguaugcaggcauccucagcuacg
<SEQ ID NO. 4582;RNA;Artificial Sequence> ggggugggcuucuuccuguucaucc
<SEQ ID NO.4583;RNA;Artificial Sequence> cuggugguggcggcugugacgcucu
<SEQ ID NO. 4584;RNA;Artificial Sequence> ugccgccugcgcagcccccccaaga
<SEQ ID NO. 4585;RNA;Artificial Sequence> aaaggccugggcucccccaccgugc
<SEQ ID NO. 4586;RNA;Artificial Sequence> cacaagaucucccgcuucccgcuca
<SEQ ID NO.4587;RNA;Artiicial Sequence> aagcgacaggugucccuggagucca
<SEQ ID NO. 4588;RNA;Artificial Sequence> aacgcguccaugagcuccaacacac
<SEQ ID NO. 4589;RNA;Artificial Sequence> ccacuggugcgcaucgcaaggcugu
<SEQ ID NO. 4590;RNA;Artificial Sequence> uccucaggggagggccccacgcugg
<SEQ ID NO.4591;RNA;Artificial Sequence> gccaaugucuccgagcucgagcugc
<SEQ ID NO. 4592;RNA;Artificial Sequence> ccugccgaccccaaaugggagcugu
<SEQ ID NO.4593;RNA;Artificial Sequence> ucucgggcccggcugacccugggca
<SEQ ID NO. 4594;RNA;Artificial Sequence> aagccccuuggggagggcugcuucg
<SEQ ID NO. 4595;RNA;Artificial Sequence> ggccagguggucauggcggaggcca
<SEQ ID NO. 4596;RNA;Artificial Sequence> aucggcauugacaaggaccgggccg
<SEQ ID NO. 4597;RNA;Artificial Sequence> gccaagccugucaccguagccguga
<SEQ ID NO. 4598;RNA;Artificial Sequence> aagaugcugaaagacgaugccacug
<SEQ ID NO. 4599;RNA;Artificial Sequence> gacaaggaccugucggaecuggugu
<SEQ ID NO. 4600;RNA;Artificial Sequence> ucugagauggagaugaugaagauga
<SEQ ID NO. 4601;RNA;Artificial Sequence> aucgggaaacacaaaaacaucauca
<SEQ ID NO. 4602;RNA;Artificial Sequence> aaccugcugggcgccugcacgcagg
<SEQ ID NO. 4603;RNA;Artificial Sequence> ggcgggccccuguacgugcuggugg
<SEQ ID NO. 4604;RNA;Artificial Sequence> gaguacgcggccaaggguaaccugc
<SEQ ID NO. 4605;RNA;Artificial Sequence> cgggaguuucugcgggcgcggcggc
<SEQ ID NO. 4606;RNA;Artificial Sequence> cccccgggccuggacuacuccuucg
<SEQ ID NO. 4607;RNA;Artificial Sequence> gacaccugcaagccgcccgaggagc
<SEQ ID NO. 4608;RNA;Artificial Sequence> cagcucaccuucaaggaccuggugu
<SEQ ID NO. 4609;RNA;Artificial Sequence> uccugugccuaccagguggcccggg
<SEQ ID NO. 4610;RNA;Artificial Sequence> ggcauggaguacuuggccucccaga
<SEQ ID NO. 461 1;RNA;Artificial Sequence> aagugcauccacagggaccuggcug
<SEQ ID NO. 4612;RNA;Artificial Sequence> gcccgcaaugugcuggugaccgagg
<SEQ ID NO. 4613;RNA; Artificial Sequence> gacaacgugaugaagaucgcagacu
<SEQ ID NO. 4614;RNA;Artificial Sequence> uucgggcuggcccgggacgugcaca
<SEQ ID NO. 4615;RNA;Artificial Sequence> aaccucgacuacuacaagaagacaa
<SEQ ID NO. 4616;RNA;Artificial Sequence> accaacggccggcugcccgugaagu
<SEQ ID NO. 4617;RNA;Artificial Sequence> uggauggcgccugaggccuuguuug
<SEQ ID NO. 4618;RNA;Artificial Sequence> gaccgagucuacacucaccagagug
<SEQ ID NO. 4619;RNA;Artificial Sequence> gacgucugguccuuugggguccugc
<SEQ ID NO. 4620;RNA;Artificial Sequence> cucugggagaucuucacgcuggggg
<SEQ ID NO. 4621;RNA;Artificial Sequence> ggcuccccguaccccggcaucccug
<SEQ ID NO.4622;RNA;Artificial Sequence> guggaggagcucuucaagcugcuga
<SEQ ID NO. 4623;RNA;Artificial Sequence> aaggagggccaccgcauggacaagc
<SEQ ID NO. 4624;RNA;Artificial Sequence> cccgccaacugcacacacgaccugu
<SEQ ID NO. 4625;RNA;Artificial Sequence> uacaugaucaugcgggagugcuggc
<SEQ ID NO. 4626;RNA;Artificial Sequence> caugccgcgcccucccagaggccca
<SEQ ID NO. 4627;RNA;Artificial Sequence> accuucaagcagcugguggaggacc
<SEQ ID NO. 4628;RNA;Artificial Sequence> cuggaccguguccuuaccgugacgu
<SEQ ID NO. 4629;RNA;Artificial Sequence> uccaccgacgaguaccuggaccugu
<SEQ ID NO. 4630;RNA;Artificial Sequence> ucggcgccuuucgagcaguacuccc
<SEQ ID NO. 4631;RNA;Artificial Sequence> ccggguggccaggacacccccagcu
<SEQ ID NO. 4632;RNA;Artificial Sequence> uccagcuccucaggggacgacuccg
<SEQ ID NO. 4633;RNA;Artificial Sequence> guguuugcccacgaccugcugcccc
<SEQ ID NO. 4634;RNA;Artificial Sequence> ccggccccacccagcagugggggcu
<SEQ ID NO. 4635;RNA;Artificial Sequence> ucgcggacgugaagggccacugguc
<SEQ ID NO. 4636;RNA;Artificial Sequence> ccccaacaaugugaggggucccuag
<SEQ ID NO. 4637;RNA;Artificial Sequence> gcagcccucccugcugcuggugcac
<SEQ ID NO. 4638;RNA;Artificial Sequence> cagccacuccccggcaugagacuca
741-3742

CA 02677068 2009-09-01
<SEQ ID NO. 4639;RNA;Artificial Sequence> agugcagauggagagacagcuacac
<SEQ ID NO. 4640;RNA;Artificial Sequence> cagagcuuuggucugugugugugug
<SEQ ID NO. 4641;RNA;Artificial Sequence> gugugcgugugugugugugugugca
<SEQ ID NO. 4642;RNA;Artificial Sequence> acauccgcgugugccugugugcgug
<SEQ ID NO. 4643;RNA;Artificial Sequence> gcgcaucuugccuccaggugcagag
<SEQ ID NO. 4644;RNA;Artificial Sequence> gguacccuggguguccccgcugcug
<SEQ ID NO. 4645;RNA;Artificial Sequence> gugcaacggucuccugacuggugcu
<SEQ ID NO. 4646;RNA;Artificial Sequence> ugcagcaccgaggggccuuuguucu
<SEQ ID NO. 4647;RNA;Artificial Sequence> uggggggacccagugcagaauguaa
<SEQ ID NO. 4648;RNA;Artificial Sequence> agugggcccacccggugggaccccg
<SEQ ID NO. 4649;RNA;Artificial Sequence> guggggcagggagcugggcccgaca
<SEQ ID NO. 4650;RNA;Artificial Sequence> auggcucggccucugccuuugcacc
<SEQ ID NO. 4651;RNA;Artificial Sequence> cacgggacaucacagggugcgcucg
<SEQ ID NO. 4652;RNA;Artificial Sequence> ggccccucccacacccaaagcugag
<SEQ ID NO. 4653;RNA;Artificial Sequence> gccugcagggaagccccacaugucc
<SEQ ID NO. 4654;RNA;Artificial Sequence> cagcaccuugugccugggguguuag
<SEQ ID NO. 4655;RNA;Artificial Sequence> guggcaccgccuccccaccuccagg
<SEQ ID NO. 4656;RNA;Artificial Sequence> gcuuucccacuucccacccugcccc
<SEQ ID NO. 4657;RNA;Artificial Sequence> cucagagacugaaauuacggguacc
<SEQ ID NO. 4658;RNA;Artificial Sequence> cugaagaugggagccuuuaccuuuu
<SEQ ID NO. 4659;RNA;Artificial Sequence> uaugcaaaagguuuauuccggaaac
<SEQ ID NO. 4660;RNA;Artificial Sequence> cuaguguacauuucuauaaauagau
<SEQ ID NO. 4661;RNA;Artificial Sequence> ugcuguguauaugguauauauacau
<SEQ ID NO. 4662;RNA;Artificial Sequence> uauauauauauaacauauauggaag
<SEQ ID NO. 4663;RNA;Artificial Sequence> gaggaaaaggcugguacaacggagg
<SEQ ID NO. 4664;RNA;Artificial Sequence> gccugcgacccugggggcacaggag
<SEQ ID NO. 4665;RNA;Artificial Sequence> ggcaggcauggcccugggcggggcg
<SEQ ID NO. 4666;RNA;Artificial Sequence> gugggggggcguggagggaggcccc
<SEQ ID NO.4667;RNA;Artificial Sequence> caggggucucacccaugcaagcaga
<SEQ ID NO. 4668;RNA;Artificial Sequence> aggaccagggcuuuuucuggcaccg
<SEQ ID NO. 4669;RNA;Artificial Sequence> gcaguuuuguuuuaaaacuggaccu
<SEQ ID NO. 4670;RNA;Artificial Sequence> uguauauuuguaaagcuauuuaugg
<SEQ ID NO. 4671;RNA;Artificial Sequence> ggccccuggcacucuuguucccaca
<SEQ ID NO. 4672;RNA;Artificial Sequence> accccaacacuuccagcauuuagcu
<SEQ ID NO. 4673;RNA;Artificial Sequence> uggccacauggcggagaguuuuaau
<SEQ ID NO. 4674;RNA;Artificial Sequence> uuuuuaacuuauugacaaccgagaa
<SEQ ID NO. 4675;RNA;Artificial Sequence> agguuuaucccgccgauagagggac
<SEQ ID NO. 4676;RNA;Artificial Sequence> cggccaagaauguacguccagccug
<SEQ ID NO. 4677;RNA;Artificial Sequence> gccccggagcuggaggauccccucc
<SEQ ID NO. 4678;RNA;Artificial Sequence> caagccuaaaagguuguuaauaguu
<SEQ ID NO. 4679;RNA;Artificial Sequence> uggaggugauuccagugaagauauu
<SEQ ID NO. 4680;RNA;Artificial Sequence> uuuauuugcuuuguccuuuuucagg
<SEQ ID NO. 4681;RNA;Artificial Sequence> gagaauuagauuucuauaggauuuu
<SEQ ID NO. 4682;RNA;Artificial Sequence> uucuuuaggagauuuauuuuuugga
<SEQ ID NO. 4683;RNA;Artificial Sequence> acuucaaagcaagcugguauuuuca
<SEQ ID NO. 4684;RNA;Artificial Sequence> auacaaauucuucuaauugcugugu
<SEQ ID NO. 4685;RNA;Artificial Sequence> ugucccaggcagggagacgguuucc
<SEQ ID NO. 4686;RNA;Artificial Sequence> cagggaggggccggcccugugugca
<SEQ ID NO. 4687;RNA;Artificial Sequence> agguuccgauguuauuagauguuac
<SEQ ID NO. 4688;RNA;Artificial Sequence> caaguuuauauauaucuauauauau
<SEQ ID NO. 4689;RNA;Artificial Sequence> uaauuuauugaguuuuuacaagaug
<SEQ ID NO. 4690;RNA;Artificial Sequence> guauuuguuguagacuuaacacuuc
<SEQ ID NO. 4691;RNA;Artificial Sequence> cuuacgcaaugcuucuagaguuuua
<SEQ ID NO. 4692;RNA;Artificial Sequence> auagccuggacugcuaccuuucaaa
<SEQ ID NO. 4693;RNA;Artificial Sequence> agcuuggagggaagccgugaauuca
<SEQ ID NO. 4694;RNA;Artificial Sequence> aguugguucguucuguacuguuacu
<SEQ ID NO. 4695;RNA;Artificial Sequence> ugggcccugagucugggcagcuguc
<SEQ ID NO. 4696;RNA;Artificial Sequence> cccuugcuugccugcagggccaugg
<SEQ ID NO. 4697;RNA;Artificial Sequence> gcucaggguggucucuucuuggggc
<SEQ ID NO. 4698;RNA;Artificial Sequence> cccagugcaugguggccagaggugu
<SEQ ID NO. 4699;RNA;Artificial Sequence> ucacccaaaccggcaggugcgauuu
<SEQ ID NO. 4700;RNA;Artificial Sequence> uuguuaacccagcgacgaacuuucc
<SEQ ID NO. 4701;RNA;Artificial Sequence> cgaaaaauaaagacaccugguugcu
<SEQ ID NO. 4702;RNA;Artificial Sequence> gugcucaaggugucccuggagucca
<SEQ ID NO. 4703;RNA;Homo sapiens>
GAAGGCAGUUGGUGGGAAGUCCAGCUUGGGUCCCUGAGAGCUGUGAGAAGGAGAUGCGGCUGCUGCUGGC
CCUGUUGGGGGUCCUGCUGAGUGUGCCUGGGCCUCCAGUCUUGUCCCUGGAGGCCUCUGAGGAAGUGGAGCUUGAGC
CCUGCCUGGCUCCCAGCCUGGAGCAGCAAGAGCAGGAGCUGACAGUAGCCCUUGGGCAGCCUGUGCGUCUGUGCUGU
GGGCGGGCUGAGCGUGGUGGCCACUGGUACAAGGAGGGCAGUCGCCUGGCACCUGCUGGCCGUGUACGGGGCUGGAG
GGGCCGCCUAGAGAUUGCCAGCUUCCUACCUGAGGAUGCUGGCCGCUACCUCUGCCUGGCACGAGGCUCCAUGAUCG
UCCUGCAGAAUCUCACCUUGAUUACAGGUGACUCCUUGACCUCCAGCAACGAUGAUGAGGACCCCAAGUCCCAUAGG
GACCCCUCGAAUAGGCACAGUUACCCCCAGCAAGCACCCUACUGGACACACCCCCAGCGCAUGGAGAAGAAACUGCA
UGCAGUACCUGCGGGGAACACCGUCAAGUUCCGCUGUCCAGCUGCAGGCAACCCCACGCCCACCAUCCGCUGGCUUA
741-3743

CA 02677068 2009-09-01
AGGAUGGACAGGCCUUUCAUGGGGAGAACCGCAUUGGAGGCAUUCGGCUGCGCCAUCAGCACUGGAGUCUCGUGAUG
GAGAGCGUGGUGCCCUCGGACCGCGGCACAUACACCUGCCUGGUAGAGAACGCUGUGGGCAGCAUCCGCUAUAACUA
CCUGCUAGAUGUGCUGGAGCGGUCCCCGCACCGGCCCAUCCUGCAGGCCGGGCUCCCGGCCAACACCACAGCCGUGGU
GGGCAGCGACGUGGAGCUGCUGUGCAAGGUGUACAGCGAUGCCCAGCCCCACAUCCAGUGGCUGAAGCACAUCGUCA
UCAACGGCAGCAGCUUCGGAGCCGACGGUUUCCCCUAUGUGCAAGUCCUAAAGACUGCAGACAUCAAUAGCUCAGAG
GUGGAGGUCCUGUACCUGCGGAACGUGUCAGCCGAGGACGCAGGCGAGUACACCUGCCUCGCAGGCAAUUCCAUCGG
CCUCUCCUACCAGUCUGCCUGGCUCACGGUGCUGCCAGGUACUGGGCGCAUCCCCCACCUCACAUGUGACAGCCUGAC
UCCAGCAGGCAGAACCAAGUCUCCCACUUUGCAGUUCUCCCUGGAGUCAGGCUCUUCCGGCAAGUCAAGCUCAUCCC
UGGUACGAGGCGUGCGUCUCUCCUCCAGCGGCCCCGCCUUGCUCGCCGGCCUCGUGAGUCUAGAUCUACCUCUCGACC
CACUAUGGGAGUUCCCCCGGGACAGGCUGGUGCUUGGGAAGCCCCUAGGCGAGGGCUGCUUUGGCCAGGUAGUACGU
GCAGAGGCCUUUGGCAUGGACCCUGCCCGGCCUGACCAAGCCAGCACUGUGGCCGUCAAGAUGCUCAAAGACAACGC
CUCUGACAAGGACCUGGCCGACCUGGUCUCGGAGAUGGAGGUGAUGAAGCUGAUCGGCCGACACAAGAACAUCAUCA
ACCUGCUUGGUGUCUGCACCCAGGAAGGGCCCCUGUACGUGAUCGUGGAGUGCGCCGCCAAGGGAAACCUGCGGGAG
UUCCUGCGGGCCCGGCGCCCCCCAGGCCCCGACCUCAGCCCCGACGGUCCUCGGAGCAGUGAGGGGCCGCUCUCCUUC
CCAGUCCUGGUCUCCUGCGCCUACCAGGUGGCCCGAGGCAUGCAGUAUCUGGAGUCCCGGAAGUGUAUCCACCGGGA
CCUGGCUGCCCGCAAUGUGCUGGUGACUGAGGACAAUGUGAUGAAGAUUGCUGACUUUGGGCUGGCCCGCGGCGUCC
ACCACAUUGACUACUAUAAGAAAACCAGCAACGGCCGCCUGCCUGUGAAGUGGAUGGCGCCCGAGGCCUUGUUUGAC
CGGGUGUACACACACCAGAGUGACGUGUGGUCUUUUGGGAUCCUGCUAUGGGAGAUCUUCACCCUCGGGGGCUCCCC
GUAUCCUGGCAUCCCGGUGGAGGAGCUGUUCUCGCUGCUGCGGGAGGGACAUCGGAUGGACCGACCCCCACACUGCC
CCCCAGAGCUGUACGGGCUGAUGCGUGAGUGCUGGCACGCAGCGCCCUCCCAGAGGCCUACCUUCAAGCAGCUGGUG
GAGGCGCUGGACAAGGUCCUGCUGGCCGUCUCUGAGGAGUACCUCGACCUCCGCCUGACCUUCGGACCCUAUUCCCC
CUCUGGUGGGGACGCCAGCAGCACCUGCUCCUCCAGCGAUUCUGUCUUCAGCCACGACCCCCUGCCAUUGGGAUCCA
GCUCCUUCCCCUUCGGGUCUGGGGUGCAGACAUGAGCAAGGCUCAAGGCUGUGCAGGCACAUAGGCUGGUGGCCUUG
GGCCUUGGGGCUCAGCCACAGCCUGACACAGUGCUCGACCUUGAUAGCAUGGGGCCCCUGGCCCAGAGUUGCUGUGC
CGUGUCCAAGGGCCGUGCCCUUGCCCUUGGAGCUGCCGUGCCUGUGUCCUGAUGGCCCAAAUGUCAGGGUUCUGCUC
GGCUUCUUGGACCUUGGCGCUUAGUCCCCAUCCCGGGUUUGGCUGAGCCUGGCUGGAGAGCUGCUAUGCUAAACCUC
CUGCCUCCCAAUACCAGCAGGAGGUUCUGGGCCUCUGAACCCCCUUUCCCCACACCUCCCCCUGCUGCUGCUGCCCCA
GCGUCUUGACGGGAGCAUUGGCCCCUGAGCCCAGAGAAGCUGGAAGCCUGCCGAAAACAGGAGCAAAUGGCGUUUUA
UAAAUUAUUUUUUUGAAAUAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 4704;RNA;Homo sapiens>
CUCGCUCCCGGCCGAGGAGCGCUCGGGCUGUCUGCGGACCCUGCCGCGUGCAGGGGUCGCGGCCGGCUGGA
GCUGGGAGUGAGGCGGCGGAGGAGCCAGGUGAGGAGGAGCCAGGUGAGCAGGACCCUGUGCUGGGCGCGGAGUCAC
GCAGGCUCGAGGAAGGCAGUUGGUGGGAAGUCCAGCUUGGGUCCCUGAGAGCUGUGAGAAGGAGAUGCGGCUGCUG
CUGGCCCUGUUGGGGGUCCUGCUGAGUGUGCCUGGGCCUCCAGUCUUGUCCCUGGAGGCCUCUGAGGAAGUGGAGCU
UGAGCCCUGCCUGGCUCCCAGCCUGGAGCAGCAAGAGCAGGAGCUGACAGUAGCCCUUGGGCAGCCUGUGCGUCUGU
GCUGUGGGCGGGCUGAGCGUGGUGGCCACUGGUACAAGGAGGGCAGUCGCCUGGCACCUGCUGGCCGUGUACGGGGC
UGGAGGGGCCGCCUAGAGAUUGCCAGCUUCCUACCUGAGGAUGCUGGCCGCUACCUCUGCCUGGCACGAGGCUCCAU
GAUCGUCCUGCAGAAUCUCACCUUGAUUACAGGUGACUCCUUGACCUCCAGCAACGAUGAUGAGGACCCCAAGUCCC
AUAGGGACCCCUCGAAUAGGCACAGUUACCCCCAGCAAGCACCCUACUGGACACACCCCCAGCGCAUGGAGAAGAAA
CUGCAUGCAGUACCUGCGGGGAACACCGUCAAGUUCCGCUGUCCAGCUGCAGGCAACCCCACGCCCACCAUCCGCUGG
CUUAAGGAUGGACAGGCCUUUCAUGGGGAGAACCGCAUUGGAGGCAUUCGGCUGCGCCAUCAGCACUGGAGUCUCGU
GAUGGAGAGCGUGGUGCCCUCGGACCGCGGCACAUACACCUGCCUGGUAGAGAACGCUGUGGGCAGCAUCCGCUAUA
ACUACCUGCUAGAUGUGCUGGAGCGGUCCCCGCACCGGCCCAUCCUGCAGGCCGGGCUCCCGGCCAACACCACAGCCG
UGGUGGGCAGCGACGUGGAGCUGCUGUGCAAGGUGUACAGCGAUGCCCAGCCCCACAUCCAGUGGCUGAAGCACAUC
GUCAUCAACGGCAGCAGCUUCGGAGCCGACGGUUUCCCCUAUGUGCAAGUCCUAAAGACUGCAGACAUCAAUAGCUC
AGAGGUGGAGGUCCUGUACCUGCGGAACGUGUCAGCCGAGGACGCAGGCGAGUACACCUGCCUCGCAGGCAAUUCCA
UCGGCCUCUCCUACCAGUCUGCCUGGCUCACGGUGCUGCCAGAGGAGGACCCCACAUGGACCGCAGCAGCGCCCGAG
GCCAGGUAUACGGACAUCAUCCUGUACGCGUCGGGCUCCCUGGCCUUGGCUGUGCUCCUGCUGCUGGCCGGGCUGUA
UCGAGGGCAGGCGCUCCACGGCCGGCACCCCCGCCCGCCCGCCACUGUGCAGAAGCUCUCCCGCUUCCCUCUGGCCCG
ACAGUUCUCCCUGGAGUCAGGCUCUUCCGGCAAGUCAAGCUCAUCCCUGGUACGAGGCGUGCGUCUCUCCUCCAGCG
GCCCCGCCUUGCUCGCCGGCCUCGUGAGUCUAGAUCUACCUCUCGACCCACUAUGGGAGUUCCCCCGGGACAGGCUG
GUGCUUGGGAAGCCCCUAGGCGAGGGCUGCUUUGGCCAGGUAGUACGUGCAGAGGCCUUUGGCAUGGACCCUGCCCG
GCCUGACCAAGCCAGCACUGUGGCCGUCAAGAUGCUCAAAGACAACGCCUCUGACAAGGACCUGGCCGACCUGGUCU
CGGAGAUGGAGGUGAUGAAGCUGAUCGGCCGACACAAGAACAUCAUCAACCUGCUUGGUGUCUGCACCCAGGAAGGG
CCCCUGUACGUGAUCGUGGAGUGCGCCGCCAAGGGAAACCUGCGGGAGUUCCUGCGGGCCCGGCGCCCCCCAGGCCCC
GACCUCAGCCCCGACGGUCCUCGGAGCAGUGAGGGGCCGCUCUCCUUCCCAGUCCUGGUCUCCUGCGCCUACCAGGUG
GCCCGAGGCAUGCAGUAUCUGGAGUCCCGGAAGUGUAUCCACCGGGACCUGGCUGCCCGCAAUGUGCUGGUGACUGA
GGACAAUGUGAUGAAGAUUGCUGACUUUGGGCUGGCCCGCGGCGUCCACCACAUUGACUACUAUAAGAAAACCAGCA
ACGGCCGCCUGCCUGUGAAGUGGAUGGCGCCCGAGGCCUUGUUUGACCGGGUGUACACACACCAGAGUGACGUGUGG
UCUUUUGGGAUCCUGCUAUGGGAGAUCUUCACCCUCGGGGGCUCCCCGUAUCCUGGCAUCCCGGUGGAGGAGCUGUU
CUCGCUGCUGCGGGAGGGACAUCGGAUGGACCGACCCCCACACUGCCCCCCAGAGCUGUACGGGCUGAUGCGUGAGU
GCUGGCACGCAGCGCCCUCCCAGAGGCCUACCUUCAAGCAGCUGGUGGAGGCGCUGGACAAGGUCCUGCUGGCCGUC
UCUGAGGAGUACCUCGACCUCCGCCUGACCUUCGGACCCUAUUCCCCCUCUGGUGGGGACGCCAGCAGCACCUGCUCC
UCCAGCGAUUCUGUCUUCAGCCACGACCCCCUGCCAUUGGGAUCCAGCUCCUUCCCCUUCGGGUCUGGGGUGCAGAC
AUGAGCAAGGCUCAAGGCUGUGCAGGCACAUAGGCUGGUGGCCUUGGGCCUUGGGGCUCAGCCACAGCCUGACACAG
UGCUCGACCUUGAUAGCAUGGGGCCCCUGGCCCAGAGUUGCUGUGCCGUGUCCAAGGGCCGUGCCCUUGCCCUUGGA
GCUGCCGUGCCUGUGUCCUGAUGGCCCAAAUGUCAGGGUUCUGCUCGGCUUCUUGGACCUUGGCGCUUAGUCCCCAU
CCCGGGUUUGGCUGAGCCUGGCUGGAGAGCUGCUAUGCUAAACCUCCUGCCUCCCAAUACCAGCAGGAGGUUCUGGG
CCUCUGAACCCCCUUUCCCCACACCUCCCCCUGCUGCUGCUGCCCCAGCGUCUUGACGGGAGCAUUGGCCCCUGAGCC
CAGAGAAGCUGGAAGCCUGCCGAAAACAGGAGCAAAUGGCGUUUUAUAAAUUAUUUUUUUGAAAUAAAAAAAAAAA
AAAAAA
<SEQ ID NO.4705;RNA;Homo sapiens>
CUCGCUCCCGGCCGAGGAGCGCUCGGGCUGUCUGCGGACCCUGCCGCGUGCAGGGGUCGCGGCCGGCUGGA
741-3744

CA 02677068 2009-09-01
GCUGGGAGUGAGGCGGCGGAGGAGCCAGGUGAGGAGGAGCCAGGAAGGCAGUUGGUGGGAAGUCCAGCUUGGGUCC
CUGAGAGCUGUGAGAAGGAGAUGCGGCUGCUGCUGGCCCUGUUGGGGGUCCUGCUGAGUGUGCCUGGGCCUCCAGUC
UUGUCCCUGGAGGCCUCUGAGGAAGUGGAGCUUGAGCCCUGCCUGGCUCCCAGCCUGGAGCAGCAAGAGCAGGAGCU
GACAGUAGCCCUUGGGCAGCCUGUGCGUCUGUGCUGUGGGCGGGCUGAGCGUGGUGGCCACUGGUACAAGGAGGGCA
GUCGCCUGGCACCUGCUGGCCGUGUACGGGGCUGGAGGGGCCGCCUAGAGAUUGCCAGCUUCCUACCUGAGGAUGCU
GGCCGCUACCUCUGCCUGGCACGAGGCUCCAUGAUCGUCCUGCAGAAUCUCACCUUGAUUACAGGUGACUCCUUGAC
CUCCAGCAACGAUGAUGAGGACCCCAAGUCCCAUAGGGACCCCUCGAAUAGGCACAGUUACCCCCAGCAAGCACCCU
ACUGGACACACCCCCAGCGCAUGGAGAAGAAACUGCAUGCAGUACCUGCGGGGAACACCGUCAAGUUCCGCUGUCCA
GCUGCAGGCAACCCCACGCCCACCAUCCGCUGGCUUAAGGAUGGACAGGCCUUUCAUGGGGAGAACCGCAUUGGAGG
CAUUCGGCUGCGCCAUCAGCACUGGAGUCUCGUGAUGGAGAGCGUGGUGCCCUCGGACCGCGGCACAUACACCUGCC
UGGUAGAGAACGCUGUGGGCAGCAUCCGCUAUAACUACCUGCUAGAUGUGCUGGAGCGGUCCCCGCACCGGCCCAUC
CUGCAGGCCGGGCUCCCGGCCAACACCACAGCCGUGGUGGGCAGCGACGUGGAGCUGCUGUGCAAGGUGUACAGCGA
UGCCCAGCCCCACAUCCAGUGGCUGAAGCACAUCGUCAUCAACGGCAGCAGCUUCGGAGCCGACGGUUUCCCCUAUG
UGCAAGUCCUAAAGACUGCAGACAUCAAUAGCUCAGAGGUGGAGGUCCUGUACCUGCGGAACGUGUCAGCCGAGGAC
GCAGGCGAGUACACCUGCCUCGCAGGCAAUUCCAUCGGCCUCUCCUACCAGUCUGCCUGGCUCACGGUGCUGCCAGA
GGAGGACCCCACAUGGACCGCAGCAGCGCCCGAGGCCAGGUAUACGGACAUCAUCCUGUACGCGUCGGGCUCCCUGG
CCUUGGCUGUGCUCCUGCUGCUGGCCGGGCUGUAUCGAGGGCAGGCGCUCCACGGCCGGCACCCCCGCCCGCCCGCCA
CUGUGCAGAAGCUCUCCCGCUUCCCUCUGGCCCGACAGUUCUCCCUGGAGUCAGGCUCUUCCGGCAAGUCAAGCUCA
UCCCUGGUACGAGGCGUGCGUCUCUCCUCCAGCGGCCCCGCCUUGCUCGCCGGCCUCGUGAGUCUAGAUCUACCUCUC
GACCCACUAUGGGAGUUCCCCCGGGACAGGCUGGUGCUUGGGAAGCCCCUAGGCGAGGGCUGCUUUGGCCAGGUAGU
ACGUGCAGAGGCCUUUGGCAUGGACCCUGCCCGGCCUGACCAAGCCAGCACUGUGGCCGUCAAGAUGCUCAAAGACA
ACGCCUCUGACAAGGACCUGGCCGACCUGGUCUCGGAGAUGGAGGUGAUGAAGCUGAUCGGCCGACACAAGAACAUC
AUCAACCUGCUUGGUGUCUGCACCCAGGAAGGGCCCCUGUACGUGAUCGUGGAGUGCGCCGCCAAGGGAAACCUGCG
GGAGUUCCUGCGGGCCCGGCGCCCCCCAGGCCCCGACCUCAGCCCCGACGGUCCUCGGAGCAGUGAGGGGCCGCUCUC
CUUCCCAGUCCUGGUCUCCUGCGCCUACCAGGUGGCCCGAGGCAUGCAGUAUCUGGAGUCCCGGAAGUGUAUCCACC
GGGACCUGGCUGCCCGCAAUGUGCUGGUGACUGAGGACAAUGUGAUGAAGAUUGCUGACUUUGGGCUGGCCCGCGGC
GUCCACCACAUUGACUACUAUAAGAAAACCAGCAACGGCCGCCUGCCUGUGAAGUGGAUGGCGCCCGAGGCCUUGUU
UGACCGGGUGUACACACACCAGAGUGACGUGUGGUCUUUUGGGAUCCUGCUAUGGGAGAUCUUCACCCUCGGGGGCU
CCCCGUAUCCUGGCAUCCCGGUGGAGGAGCUGUUCUCGCUGCUGCGGGAGGGACAUCGGAUGGACCGACCCCCACAC
UGCCCCCCAGAGCUGUACGGGCUGAUGCGUGAGUGCUGGCACGCAGCGCCCUCCCAGAGGCCUACCUUCAAGCAGCU
GGUGGAGGCGCUGGACAAGGUCCUGCUGGCCGUCUCUGAGGAGUACCUCGACCUCCGCCUGACCUUCGGACCCUAUU
CCCCCUCUGGUGGGGACGCCAGCAGCACCUGCUCCUCCAGCGAUUCUGUCUUCAGCCACGACCCCCUGCCAUUGGGAU
CCAGCUCCUUCCCCUUCGGGUCUGGGGUGCAGACAUGAGCAAGGCUCAAGGCUGUGCAGGCACAUAGGCUGGUGGCC
UUGGGCCUUGGGGCUCAGCCACAGCCUGACACAGUGCUCGACCUUGAUAGCAUGGGGCCCCUGGCCCAGAGUUGCUG
UGCCGUGUCCAAGGGCCGUGCCCUUGCCCUUGGAGCUGCCGUGCCUGUGUCCUGAUGGCCCAAAUGUCAGGGUUCUG
CUCGGCUUCUUGGACCUUGGCGCUUAGUCCCCAUCCCGGGUUUGGCUGAGCCUGGCUGGAGAGCUGCUAUGCUAAAC
CUCCUGCCUCCCAAUACCAGCAGGAGGUUCUGGGCCUCUGAACCCCCUUUCCCCACACCUCCCCCUGCUGCUGCUGCC
CCAGCGUCUUGACGGGAGCAUUGGCCCCUGAGCCCAGAGAAGCUGGAAGCCUGCCGAAAACAGGAGCAAAUGGCGUU
UUAUAAAUUAUUUUUUUGAAAUAAAAAAAAAAAAAAAAA
<SEQ ID NO. 4706;RNA; Artificial Sequence> cucgcucccggccgaggag
<SEQ ID NO.4707;RNA;Artificial Sequence> gcgcucgggcugucugcgg
<SEQ ID NO. 4708;RNA;Artificial Sequence> gacccugccgcgugcaggg
<SEQ ID NO. 4709;RNA;Artificial Sequence> ggucgcggccggcuggagc
<SEQ ID NO. 4710;RNA;Artificial Sequence> cugggagugaggcggcgga
<SEQ ID NO. 471 1;RNA;Artificial Sequence> aggagccaggugaggagga
<SEQ ID NO.4712;RNA;Artificial Sequence> agccaggaaggcaguuggu
<SEQ ID NO. 4713;RNA;Artificial Sequence> ugggaaguccagcuugggu
<SEQ ID NO. 4714;RNA;Artificial Sequence> ucccugagagcugugagaa
<SEQ ID NO. 4715;RNA;Artificial Sequence> aggagaugcggcugcugcu
<SEQ ID NO. 4716;RNA;Artificial Sequence> uggcccuguuggggguccu
<SEQ ID NO.4717;RNA;Artificial Sequence> ugcugagugugccugggcc
<SEQ ID NO. 4718;RNA;Artificial Sequence> cuccagucuugucccugga
<SEQ ID NO. 4719;RNA;Artificial Sequence> aggccucugaggaagugga
<SEQ ID NO. 4720;RNA;Artificial Sequence> agcuugagcccugccuggc
<SEQ ID NO. 4721;RNA;Artificial Sequence> cucccagccuggagcagca
<SEQ ID NO.4722;RNA;Artificial Sequence> aagagcaggagcugacagu
<SEQ ID NO. 4723;RNA;Artificial Sequence> uagcccuugggcagccugu
<SEQ ID NO. 4724;RNA;Artificial Sequence> ugcgucugugcugugggcg
<SEQ ID NO. 4725;RNA;Artificial Sequence> gggcugagcgugguggcca
<SEQ ID NO. 4726;RNA;Artificial Sequence> acugguacaaggagggcag
<SEQ ID NO.4727;RNA;Artificial Sequence> gucgccuggcaccugcugg
<SEQ ID NO. 4728;RNA;Artificial Sequence> gccguguacggggcuggag
<SEQ ID NO.4729;RNA;Artificial Sequence> ggggccgccuagagauugc
<SEQ ID NO. 4730;RNA;Artificial Sequence> ccagcuuccuaccugagga
<SEQ ID NO. 473 1;RNA;Artificial Sequence> augcuggccgcuaccucug
<SEQ ID NO. 4732;RNA;Artificial Sequence> gccuggcacgaggcuccau
<SEQ ID NO. 4733;RNA;Artificial Sequence> ugaucguccugcagaaucu
<SEQ ID NO. 4734;RNA;Artificial Sequence> ucaccuugauuacagguga
<SEQ ID NO. 4735;RNA; Artificial Sequence> acuccuugaccuccagcaa
<SEQ ID NO. 4736;RNA;Artificial Sequence> acgaugaugaggaccccaa
<SEQ ID NO. 4737;RNA;Artificial Sequence> agucccauagggaccccuc
<SEQ ID NO. 4738;RNA;Artificial Sequence> cgaauaggcacaguuaccc
<SEQ ID NO. 4739;RNA; Artificial Sequence> cccagcaagcacccuacug
741-3745

CA 02677068 2009-09-01
<SEQ ID NO. 4740;RNA;Artificial Sequence> ggacacacccccagcgcau
<SEQ ID NO. 4741;RNA;Artificial Sequence> uggagaagaaacugcaugc
<SEQ ID NO. 4742;RNA;Artificial Sequence> caguaccugcggggaacac
<SEQ ID NO. 4743;RNA;Artificial Sequence> ccgucaaguuccgcugucc
<SEQ ID NO. 4744;RNA;Artificial Sequence> cagcugcaggcaaccccac
<SEQ ID NO. 4745;RNA;Artificial Sequence> cgcccaccauccgcuggcu
<SEQ ID NO. 4746;RNA;Artificial Sequence> uuaaggauggacaggccuu
<SEQ ID NO. 4747;RNA;Artificial Sequence> uucauggggagaaccgcau
<SEQ ID NO. 4748;RNA;Artificial Sequence> uuggaggcauucggcugcg
<SEQ ID NO. 4749;RNA;Artificial Sequence> gccaucagcacuggagucu
<SEQ ID NO.4750;RNA;Artificial Sequence> ucgugauggagagcguggu
<SEQ ID NO. 4751;RNA;Artificial Sequence> ugcccucggaccgcggcac
<SEQ ID NO. 4752;RNA;Artificial Sequence> cauacaccugccugguaga
<SEQ ID NO. 4753;RNA;Artificial Sequence> agaacgcugugggcagcau
<SEQ ID NO. 4754;RNA;Artificial Sequence> uccgcuauaacuaccugcu
<SEQ ID NO. 4755;RNA;Artificial Sequence> uagaugugcuggagcgguc
<SEQ ID NO. 4756;RNA;Artificial Sequence> ccccgcaccggcccauccu
<SEQ ID NO. 4757;RNA;Artificial Sequence> ugcaggccgggcucccggc
<SEQ ID NO. 4758;RNA;Artificial Sequence> ccaacaccacagccguggu
<SEQ ID NO. 4759;RNA;Artificial Sequence> ugggcagcgacguggagcu
<SEQ ID NO. 4760;RNA;Artificial Sequence> ugcugugcaagguguacag
<SEQ ID NO. 4761;RNA;Artificial Sequence> gcgaugcccagccccacau
<SEQ ID NO.4762;RNA;Artificial Sequence> uccaguggcugaagcacau
<SEQ ID NO. 4763;RNA;Artificial Sequence> ucgucaucaacggcagcag
<SEQ ID NO. 4764;RNA;Artificial Sequence> gcuucggagccgacgguuu
<SEQ ID NO. 4765;RNA;Artificial Sequence> uccccuaugugcaaguccu
<SEQ ID NO. 4766;RNA;Artificial Sequence> uaaagacugcagacaucaa
<SEQ ID NO. 4767;RNA;Artificial Sequence> auagcucagagguggaggu
<SEQ ID NO. 4768;RNA;Artificial Sequence> uccuguaccugcggaacgu
<SEQ ID NO.4769;RNA;Artificial Sequence> ugucagccgaggacgcagg
<SEQ ID NO. 4770;RNA;Artificial Sequence> gcgaguacaccugccucgc
<SEQ ID NO. 4771;RNA;Artificial Sequence> caggcaauuccaucggccu
<SEQ ID NO. 4772;RNA;Artificial Sequence> ucuccuaccagucugccug
<SEQ ID NO. 4773;RNA;Artificial Sequence> ggcucacggugcugccaga
<SEQ ID NO. 4774;RNA;Artificial Sequence> aggaggaccccacauggac
<SEQ ID NO.4775;RNA;Artificial Sequence> ccgcagcagcgcccgaggc
<SEQ ID NO. 4776;RNA;Artificial Sequence> ccagguauacggacaucau
<SEQ ID NO. 4777;RNA;Artificial Sequence> uccuguacgcgucgggcuc
<SEQ ID NO. 4778;RNA;Artificial Sequence> cccuggccuuggcugugcu
<SEQ ID NO. 4779;RNA;Artificial Sequence> uccugcugcuggccgggcu
<SEQ ID NO. 4780;RNA;Artificial Sequence> uguaucgagggcaggcgcu
<SEQ ID NO. 4781;RNA;Artificial Sequence> uccacggccggcacccccg
<SEQ ID NO. 4782;RNA;Artificial Sequence> gcccgcccgccacugugca
<SEQ ID NO. 4783;RNA;Artificial Sequence> agaagcucucccgcuuccc
<SEQ ID NO. 4784;RNA;Artificial Sequence> cucuggcccgacaguucuc
<SEQ ID NO. 4785;RNA;Artificial Sequence> cccuggagucaggcucuuc
<SEQ ID NO.4786;RNA;Artificial Sequence> ccggcaagucaagcucauc
<SEQ ID NO.4787;RNA;Artificial Sequence> cccugguacgaggcgugcg
<SEQ ID NO. 4788;RNA;Artificial Sequence> gucucuccuccagcggccc
<SEQ ID NO. 4789;RNA;Artificial Sequence> ccgccuugcucgccggccu
<SEQ ID NO. 4790;RNA;Artificial Sequence> ucgugagucuagaucuacc
<SEQ ID NO. 4791;RNA;Artificial Sequence> cucucgacccacuauggga
<SEQ ID NO. 4792;RNA;Artificial Sequence> aguucccccgggacaggcu
<SEQ ID NO.4793;RNA;Artificial Sequence> uggugcuugggaagccccu
<SEQ ID NO. 4794;RNA;Artificial Sequence> uaggcgagggcugcuuugg
<SEQ ID NO. 4795;RNA;Artificial Sequence> gccagguaguacgugcaga
<SEQ ID NO. 4796;RNA;Artificial Sequence> aggccuuuggcauggaccc
<SEQ ID NO. 4797;RNA;Artificial Sequence> cugcccggccugaccaagc
<SEQ ID NO. 4798;RNA;Artificial Sequence> ccagcacuguggccgucaa
<SEQ ID NO. 4799;RNA;Artificial Sequence> agaugcucaaagacaacgc
<SEQ ID NO.4800;RNA;Artificial Sequence> ccucugacaaggaccuggc
<SEQ ID NO. 4801;RNA;Artificial Sequence> ccgaccuggucucggagau
<SEQ ID NO. 4802;RNA;Artificial Sequence> uggaggugaugaagcugau
<SEQ ID NO. 4803;RNA;Artificial Sequence> ucggccgacacaagaacau
<SEQ ID NO. 4804;RNA;Artificial Sequence> ucaucaaccugcuuggugu
<SEQ ID NO. 4805;RNA;Artificial Sequence> ucugcacccaggaagggcc
<SEQ ID NO.4806;RNA;Artifrcial Sequence> cccuguacgugaucgugga
<SEQ ID NO. 4807;RNA;Artificial Sequence> agugcgccgccaagggaaa
<SEQ ID NO. 4808;RNA;Artificial Sequence> accugcgggaguuccugcg
<SEQ ID NO. 4809;RNA;Artificial Sequence> gggcccggcgccccccagg
<SEQ ID NO.4810;RNA;Artificial Sequence> gccccgaccucagccccga
<SEQ ID NO.4811;RNA;Artificial Sequence> acgguccucggagcaguga
<SEQ ID NO. 4812;RNA;Artificial Sequence> aggggccgcucuccuuccc
741-3746

CA 02677068 2009-09-01
<SEQ ID NO. 4813;RNA;Artificial Sequence> caguccuggucuccugcgc
<SEQ ID NO.4814;RNA;Artificial Sequence> ccuaccagguggcccgagg
<SEQ ID NO. 4815;RNA;Artificial Sequence> gcaugcaguaucuggaguc
<SEQ ID NO. 4816;RNA;Artificial Sequence> cccggaaguguauccaccg
<SEQ ID NO. 4817;RNA;Artificial Sequence> gggaccuggcugcccgcaa
<SEQ ID NO. 4818;RNA;Artificial Sequence> augugcuggugacugagga
<SEQ ID NO. 4819;RNA;Artificial Sequence> acaaugugaugaagauugc
<SEQ ID NO.4820;RNA;Artificial Sequence> cugacuuugggcuggcccg
<SEQ ID NO. 4821;RNA;Artificial Sequence> gcggcguccaccacauuga
<SEQ ID NO. 4822;RNA;Artificial Sequence> acuacuauaagaaaaccag
<SEQ ID NO. 4823;RNA;Artificial Sequence> gcaacggccgccugccugu
<SEQ ID NO. 4824;RNA;Artificial Sequence> ugaaguggauggcgcccga
<SEQ ID NO. 4825;RNA;Artificial Sequence> aggccuuguuugaccgggu
<SEQ ID NO. 4826;RNA;Artificial Sequence> uguacacacaccagaguga
<SEQ ID NO. 4827;RNA;Artificial Sequence> acguguggucuuuugggau
<SEQ ID NO. 4828;RNA;Artificial Sequence> uccugcuaugggagaucuu
<SEQ ID NO. 4829;RNA;Artificial Sequence> ucacccucgggggcucccc
<SEQ ID NO. 4830;RNA;Artificial Sequence> cguauccuggcaucccggu
<SEQ ID NO. 4831;RNA;Artificial Sequence> uggaggagcuguucucgcu
<SEQ ID NO. 4832;RNA;Artificial Sequence> ugcugcgggagggacaucg
<SEQ ID NO. 4833;RNA;Artificial Sequence> ggauggaccgacccccaca
<SEQ ID NO. 4834;RNA;Artificial Sequence> acugccccccagagcugua
<SEQ ID NO.4835;RNA;Artificial Sequence> acgggcugaugcgugagug
<SEQ ID NO. 4836;RNA;Artificial Sequence> gcuggcacgcagcgcccuc
<SEQ ID NO. 4837;RNA;Artificial Sequence> cccagaggccuaccuucaa
<SEQ ID NO. 4838;RNA;Artificial Sequence> agcagcugguggaggcgcu
<SEQ ID NO. 4839;RNA;Artificial Sequence> uggacaagguccugcuggc
<SEQ ID NO. 4840;RNA;Artificial Sequence> ccgucucugaggaguaccu
<SEQ ID NO. 4841;RNA;Artificial Sequence> ucgaccuccgccugaccuu
<SEQ ID NO. 4842;RNA;Artificial Sequence> ucggacccuauucccccuc
<SEQ ID NO.4843;RNA;Artificial Sequence> cugguggggacgccagcag
<SEQ ID NO. 4844;RNA;Artificial Sequence> gcaccugcuccuccagcga
<SEQ ID NO. 4845;RNA; Artificial Sequence> auucugucuucagccacga
<SEQ ID NO. 4846;RNA;Artificial Sequence> acccccugccauugggauc
<SEQ ID NO. 4847;RNA;Artificial Sequence> ccagcuccuuccccuucgg
<SEQ ID NO. 4848;RNA;Artificial Sequence> ggucuggggugcagacaug
<SEQ ID NO. 4849;RNA;Artificial Sequence> gagcaaggcucaaggcugu
<SEQ ID NO. 4850;RNA;Artificial Sequence> ugcaggcacauaggcuggu
<SEQ ID NO. 4851;RNA;Artificial Sequence> uggccuugggccuuggggc
<SEQ ID NO. 4852;RNA;Artificial Sequence> cucagccacagccugacac
<SEQ ID NO. 4853;RNA;Artificial Sequence> cagugcucgaccuugauag
<SEQ ID NO. 4854;RNA;Artificial Sequence> gcauggggccccuggccca
<SEQ ID NO. 4855;RNA;Artificial Sequence> agaguugcugugccguguc
<SEQ ID NO. 4856;RNA;Artificial Sequence> ccaagggccgugcccuugc
<SEQ ID NO. 4857;RNA;Artificial Sequence> cccuuggagcugccgugcc
<SEQ ID NO. 4858;RNA;Artificial Sequence> cuguguccugauggcccaa
<SEQ ID NO. 4859;RNA;Artificial Sequence> aaugucaggguucugcucg
<SEQ ID NO.4860;RNA;Artificial Sequence> ggcuucuuggaccuuggcg
<SEQ ID NO.4861;RNA;Artificial Sequence> gcuuaguccccaucccggg
<SEQ ID NO. 4862;RNA;Artificial Sequence> guuuggcugagccuggcug
<SEQ ID NO. 4863;RNA;Artificial Sequence> ggagagcugcuaugcuaaa
<SEQ ID NO. 4864;RNA;Artificial Sequence> accuccugccucccaauac
<SEQ ID NO.4865;RNA;Artificial Sequence> ccagcaggagguucugggc
<SEQ ID NO. 4866;RNA;Artificial Sequence> ccucugaacccccuuuccc
<SEQ ID NO. 4867;RNA;Artificial Sequence> ccacaccucccccugcugc
<SEQ ID NO. 4868;RNA;Artificial Sequence> cugcugccccagcgucuug
<SEQ ID NO. 4869;RNA;Artificial Sequence> gacgggagcauuggccccu
<SEQ ID NO. 4870;RNA;Artificial Sequence> ugagcccagagaagcugga
<SEQ ID NO. 4871;RNA;Artificial Sequence> aagccugccgaaaacagga
<SEQ ID NO.4872;RNA;Artificial Sequence> agcaaauggcguuuuauaa
<SEQ ID NO. 4873;RNA;Artificial Sequence> aauuauuuuuuugaaauaa
<SEQ ID NO. 4874;RNA;Artificial Sequence> agccaggugagcaggaccc
<SEQ ID NO. 4875;RNA;Artificial Sequence> cugugcugggcgcggaguc
<SEQ ID NO. 4876;RNA;Artificial Sequence> cacgcaggcucgaggaagg
<SEQ ID NO. 4877;RNA;Artificial Sequence> gcaguuggugggaagucca
<SEQ ID NO. 4878;RNA;Artificial Sequence> agcuugggucccugagagc
<SEQ ID NO. 4879;RNA;Artificial Sequence> cugugagaaggagaugcgg
<SEQ ID NO.4880;RNA;Artificial Sequence> gcugcugcuggcccuguug
<SEQ ID NO. 4881;RNA;Artificial Sequence> ggggguccugcugagugug
<SEQ ID NO. 4882;RNA;Artificial Sequence> gccugggccuccagucuug
<SEQ ID NO. 4883;RNA;Artificial Sequence> gucccuggaggccucugag
<SEQ ID NO. 4884;RNA;Artificial Sequence> ggaaguggagcuugagccc
<SEQ ID NO.4885;RNA;Artificial Sequence> cugccuggcucccagccug
741-3747

CA 02677068 2009-09-01
<SEQ ID NO. 4886;RNA;Artificial Sequence> ggagcagcaagagcaggag
<SEQ ID NO. 4887;RNA;Artificial Sequence> gcugacaguagcccuuggg
<SEQ ID NO. 4888;RNA;Artificial Sequence> gcagccugugcgucugugc
<SEQ ID NO.4889;RNA;Artificial Sequence> cugugggcgggcugagcgu
<SEQ ID NO. 4890;RNA;Artificial Sequence> ugguggccacugguacaag
<SEQ ID NO.4891;RNA;Artificial Sequence> ggagggcagucgccuggca
<SEQ ID NO.4892;RNA;Artificial Sequence> accugcuggccguguacgg
<SEQ ID NO.4893;RNA;Artificial Sequence> gggcuggaggggccgecua
<SEQ ID NO. 4894;RNA;Artificial Sequence> agagauugccagcuuccua
<SEQ ID NO. 4895;RNA; Artificial Sequence> accugaggaugcuggccgc
<SEQ ID NO. 4896;RNA;Artificial Sequence> cuaccucugccuggcacga
<SEQ ID NO. 4897;RNA;Artificial Sequence> aggcuccaugaucguccug
<SEQ ID NO. 4898;RNA; Artificial Sequence> gcagaaucucaccuugauu
<SEQ ID NO. 4899;RNA;Artificial Sequence> uacaggugacuccuugacc
<SEQ ID NO. 4900;RNA;Artificial Sequence> cuccagcaacgaugaugag
<SEQ ID NO. 4901;RNA;Artificial Sequence> ggaccccaagucccauagg
<SEQ ID NO. 4902;RNA;Artificial Sequence> ggaccccucgaauaggcac
<SEQ ID NO. 4903;RNA;Artificial Sequence> caguuacccccagcaagca
<SEQ ID NO. 4904;RNA;Artificial Sequence> acccuacuggacacacccc
<SEQ ID NO. 4905;RNA;Artificial Sequence> ccagcgcauggagaagaaa
<SEQ ID NO. 4906;RNA; Artificial Sequence> acugcaugcaguaccugcg
<SEQ ID NO. 4907;RNA;Artificial Sequence> ggggaacaccgucaaguuc
<SEQ ID NO. 4908;RNA;Artificial Sequence> ccgcuguccagcugcaggc
<SEQ ID NO. 4909;RNA;Artificial Sequence> caaccccacgcccaccauc
<SEQ ID NO. 4910;RNA;Artificial Sequence> ccgcuggcuuaaggaugga
<SEQ ID NO.4911;RNA;Artificial Sequence> acaggccuuucauggggag
<SEQ ID NO. 4912;RNA;Artificial Sequence> gaaccgcauuggaggcauu
<SEQ ID NO. 4913;RNA;Artificial Sequence> ucggcugcgccaucagcac
<SEQ ID NO. 4914;RNA;Artificial Sequence> cuggagucucgugauggag
<SEQ ID NO. 4915;RNA;Artificial Sequence> gagcguggugcccucggac
<SEQ ID NO. 4916;RNA;Artificial Sequence> ccgcggcacauacaccugc
<SEQ ID NO. 4917;RNA;Artificial Sequence> ccugguagagaacgcugug
<SEQ ID NO. 4918;RNA; Artificial Sequence> gggcagcauccgcuauaac
<SEQ ID NO. 4919;RNA;Artificial Sequence> cuaccugcuagaugugcug
<SEQ ID NO. 4920;RNA;Artificial Sequence> ggagcgguccccgcaccgg
<SEQ ID NO. 4921;RNA;Artificial Sequence> gcccauccugcaggccggg
<SEQ ID NO.4922;RNA;Artificial Sequence> gcucccggccaacaccaca
<SEQ ID NO. 4923;RNA;Artificial Sequence> agccguggugggcagcgac
<SEQ ID NO. 4924;RNA;Artificial Sequence> cguggagcugcugugcaag
<SEQ ID NO. 4925;RNA;Artificial Sequence> gguguacagcgaugcccag
<SEQ ID NO. 4926;RNA;Artificial Sequence> gccccacauccaguggcug
<SEQ ID NO. 4927;RNA;Artificial Sequence> gaagcacaucgucaucaac
<SEQ ID NO. 4928;RNA;Artificial Sequence> cggcagcagcuucggagcc
<SEQ ID NO. 4929;RNA;Artificial Sequence> cgacgguuuccccuaugug
<SEQ ID NO. 4930;RNA;Artificial Sequence> gcaaguccuaaagacugca
<SEQ ID NO. 4931;RNA;Artificial Sequence> agacaucaauagcucagag
<SEQ ID NO. 4932;RNA;Artificial Sequence> gguggagguccuguaccug
<SEQ ID NO. 4933;RNA;Artificial Sequence> gcggaacgugucagccgag
<SEQ ID NO. 4934;RNA;Artificial Sequence> ggacgcaggcgaguacacc
<SEQ ID NO.4935;RNA;Artificial Sequence> cugccucgcaggcaauucc
<SEQ ID NO.4936;RNA;Artificial Sequence> caucggccucuccuaccag
<SEQ ID NO. 4937;RNA;Artificial Sequence> gucugccuggcucacggug
<SEQ ID NO. 4938;RNA;Artificial Sequence> gcugccagaggaggacccc
<SEQ ID NO. 4939;RNA;Artificial Sequence> cacauggaccgcagcagcg
<SEQ ID NO. 4940;RNA;Artificial Sequence> gcccgaggccagguauacg
<SEQ ID NO. 4941;RNA;Artificial Sequence> ggacaucauccuguacgcg
<SEQ ID NO. 4942;RNA;Artificial Sequence> gucgggcucccuggccuug
<SEQ ID NO. 4943;RNA;Artificial Sequence> ggcugugcuccugcugcug
<SEQ ID NO. 4944;RNA;Artificial Sequence> ggccgggcuguaucgaggg
<SEQ ID NO. 4945;RNA;Artificial Sequence> gcaggcgcuccacggccgg
<SEQ ID NO. 4946;RNA;Artificial Sequence> gcacccccgcccgcccgcc
<SEQ ID NO. 4947;RNA;Artificial Sequence> cacugugcagaagcucucc
<SEQ ID NO. 4948;RNA;Artificial Sequence> ccgcuucccucuggcccga
<SEQ ID NO.4949;RNA;Artificial Sequence> acaguucucccuggaguca
<SEQ ID NO. 4950;RNA;Artificial Sequence> aggcucuuccggcaaguca
<SEQ ID NO. 4951;RNA;Artificial Sequence> aagcucaucccugguacga
<SEQ ID NO. 4952;RNA;Artificial Sequence> aggcgugcgucucuccucc
<SEQ ID NO. 4953;RNA;Artificial Sequence> cagcggccccgccuugcuc
<SEQ ID NO.4954;RNA;Artificial Sequence> cgccggccucgugagucua
<SEQ ID NO.4955;RNA;Artificial Sequence> agaucuaccucucgaccca
<SEQ ID NO. 4956;RNA;Artificial Sequence> acuaugggaguucccccgg
<SEQ ID NO. 4957;RNA;Artificial Sequence> ggacaggcuggugcuuggg
<SEQ ID NO. 4958;RNA;Artificial Sequence> gaagccccuaggcgagggc
741-3748

CA 02677068 2009-09-01
<SEQ ID NO. 4959;RNA;Artificial Sequence> cugcuuuggccagguagua
<SEQ ID NO. 4960;RNA;Artificial Sequence> acgugcagaggccuuuggc
<SEQ ID NO. 4961;RNA;Artificial Sequence> cauggacccugcccggccu
<SEQ ID NO. 4962;RNA;Artificial Sequence> ugaccaagccagcacugug
<SEQ ID NO. 4963;RNA;Artificial Sequence> ggccgucaagaugcucaaa
<SEQ ID NO. 4964;RNA;Artificial Sequence> agacaacgccucugacaag
<SEQ ID NO. 4965;RNA;Artificial Sequence> ggaccuggccgaccugguc
<SEQ ID NO. 4966;RNA;Artificial Sequence> cucggagauggaggugaug
<SEQ ID NO. 4967;RNA;Artificial Sequence> gaagcugaucggccgacac
<SEQ ID NO. 4968;RNA;Artificial Sequence> caagaacaucaucaaccug
<SEQ ID NO. 4969;RNA; Artificial Sequence> gcuuggugucugcacccag
<SEQ ID NO. 4970;RNA;Artificial Sequence> ggaagggccccuguacgug
<SEQ ID NO.4971;RNA;Artificial Sequence> gaucguggagugcgccgcc
<SEQ ID NO. 4972;RNA; Artificial Sequence> caagggaaaccugcgggag
<SEQ ID NO. 4973;RNA;Artificial Sequence> guuccugcgggcccggcgc
<SEQ ID NO. 4974;RNA;Artificial Sequence> ccccccaggccccgaccuc
<SEQ ID NO. 4975;RNA;Artificial Sequence> cagccccgacgguccucgg
<SEQ ID NO. 4976;RNA;Artificial Sequence> gagcagugaggggccgcuc
<SEQ ID NO. 4977;RNA;Artificial Sequence> cuccuucccaguccugguc
<SEQ ID NO. 4978;RNA;Artificial Sequence> cuccugcgccuaccaggug
<SEQ ID NO.4979;RNA;Artificial Sequence> ggcccgaggcaugcaguau
<SEQ ID NO. 4980;RNA;Artificial Sequence> ucuggagucccggaagugu
<SEQ ID NO.4981;RNA;Artificial Sequence> uauccaccgggaccuggcu
<SEQ ID NO. 4982;RNA;Artificial Sequence> ugcccgcaaugugcuggug
<SEQ ID NO. 4983;RNA; Artificial Sequence> gacugaggacaaugugaug
<SEQ ID NO. 4984;RNA;Artificial Sequence> gaagauugcugacuuuggg
<SEQ ID NO.4985;RNA;Artificial Sequence> gcuggcccgcggcguccac
<SEQ ID NO. 4986;RNA;Artificial Sequence> ccacauugacuacuauaag
<SEQ ID NO. 4987;RNA;Artificial Sequence> gaaaaccagcaacggccgc
<SEQ ID NO. 4988;RNA;Artificial Sequence> ccugccugugaaguggaug
<SEQ ID NO. 4989;RNA;Artificial Sequence> ggcgcccgaggccuuguuu
<SEQ ID NO. 4990;RNA; Artificial Sequence> ugaccggguguacacacac
<SEQ ID NO. 4991;RNA;Artificial Sequence> ccagagugacguguggucu
<SEQ ID NO.4992;RNA;Artificial Sequence> uuuugggauccugcuaugg
<SEQ ID NO. 4993;RNA;Artificial Sequence> ggagaucuucacccucggg
<SEQ ID NO. 4994;RNA;Artificial Sequence> gggcuccccguauccuggc
<SEQ ID NO. 4995;RNA;Artificial Sequence> caucccgguggaggagcug
<SEQ ID NO. 4996;RNA;Artificial Sequence> guucucgcugcugcgggag
<SEQ ID NO. 4997;RNA;Artificial Sequence> gggacaucggauggaccga
<SEQ ID NO. 4998;RNA;Artificial Sequence> acccccacacugcccccca
<SEQ ID NO. 4999;RNA;Artificial Sequence> agagcuguacgggcugaug
<SEQ ID NO.5000;RNA;Artificial Sequence> gcgugagugcuggcacgca
<SEQ ID NO. 5001;RNA;Artificial Sequence> agcgcccucccagaggccu
<SEQ ID NO. 5002;RNA;Artificial Sequence> uaccuucaagcagcuggug
<SEQ ID NO. 5003;RNA;Artificial Sequence> ggaggcgcuggacaagguc
<SEQ ID NO. 5004;RNA;Artificial Sequence> ccugcuggccgucucugag
<SEQ ID NO. 5005;RNA;Artificial Sequence> ggaguaccucgaccuccgc
<SEQ ID NO. 5006;RNA;Artificial Sequence> ccugaccuucggacccuau
<SEQ ID NO. 5007;RNA;Artificial Sequence> uucccccucugguggggac
<SEQ ID NO. 5008;RNA;Artificial Sequence> cgccagcagcaccugcucc
<SEQ ID NO. 5009;RNA;Artificial Sequence> cuccagcgauucugucuuc
<SEQ ID NO. 5010;RNA;Artificial Sequence> cagccacgacccccugcca
<SEQ ID NO.5011;RNA;Artificial Sequence> auugggauccagcuccuuc
<SEQ ID NO. 5012;RNA;Artificial Sequence> ccccuucgggucuggggug
<SEQ ID NO. 5013;RNA;Artificial Sequence> gcagacaugagcaaggcuc
<SEQ ID NO. 5014;RNA;Artificial Sequence> caaggcugugcaggcacau
<SEQ ID NO. 5015;RNA;Artificial Sequence> uaggcugguggccuugggc
<SEQ ID NO. 5016;RNA;Artificial Sequence> ccuuggggcucagccacag
<SEQ ID NO. 5017;RNA;Artificial Sequence> gccugacacagugcucgac
<SEQ ID NO. 5018;RNA;Artificial Sequence> ccuugauagcauggggccc
<SEQ ID NO. 5019;RNA;Artificial Sequence> ccuggcccagaguugcugu
<SEQ ID NO. 5020;RNA;Artificial Sequence> ugccguguccaagggccgu
<SEQ ID NO. 5021;RNA;Artificial Sequence> ugcccuugcccuuggagcu
<SEQ ID NO. 5022;RNA; Artificial Sequence> ugccgugccuguguccuga
<SEQ ID NO. 5023;RNA;Artificial Sequence> auggcccaaaugucagggu
<SEQ ID NO. 5024;RNA;Artificial Sequence> uucugcucggcuucuugga
<SEQ ID NO. 5025;RNA;Artificial Sequence> accuuggcgcuuagucccc
<SEQ ID NO. 5026;RNA;Artificial Sequence> caucccggguuuggcugag
<SEQ ID NO. 5027;RNA;Artificial Sequence> gccuggcuggagagcugcu
<SEQ ID NO. 5028;RNA;Artificial Sequence> uaugcuaaaccuccugccu
<SEQ ID NO. 5029;RNA;Artificial Sequence> ucccaauaccagcaggagg
<SEQ ID NO. 5030;RNA;Artificial Sequence> guucugggccucugaaccc
<SEQ ID NO. 5031;RNA;Artificial Sequence> cccuuuccccacaccuccc
741-3749

CA 02677068 2009-09-01
<SEQ ID NO. 5032;RNA;Artificial Sequence> cccugcugcugcugcccca
<SEQ ID NO. 5033;RNA;Artificial Sequence> agcgucuugacgggagcau
<SEQ ID NO. 5034;RNA;Artificial Sequence> uuggccccugagcccagag
<SEQ ID NO. 5035;RNA;Artificial Sequence> gaagcuggaagccugccga
<SEQ ID NO. 5036;RNA;Artificial Sequence> aaaacaggagcaaauggcg
<SEQ ID NO. 5037;RNA;Artificial Sequence> guuuuauaaauuauuuuuu
<SEQ ID NO. 5038;RNA; Artificial Sequence> gaaggcaguuggugggaag
<SEQ ID NO. 5039;RNA;Artificial Sequence> guccagcuugggucccuga
<SEQ ID NO. 5040;RNA;Artificial Sequence> agagcugugagaaggagau
<SEQ ID NO. 5041;RNA;Artificial Sequence> ugcggcugcugcuggcccu
<SEQ ID NO. 5042;RNA;Artificial Sequence> uguuggggguccugcugag
<SEQ ID NO. 5043;RNA;Artificial Sequence> gugugccugggccuccagu
<SEQ ID NO. 5044;RNA;Artificial Sequence> ucuugucccuggaggccuc
<SEQ ID NO. 5045;RNA;Artificial Sequence> cugaggaaguggagcuuga
<SEQ ID NO. 5046;RNA;Artificial Sequence> agcccugccuggcucccag
<SEQ ID NO. 5047;RNA;Artificial Sequence> gccuggagcagcaagagca
<SEQ ID NO. 5048;RNA;Artificial Sequence> aggagcugacaguagcccu
<SEQ ID NO. 5049;RNA;Artificial Sequence> uugggcagccugugcgucu
<SEQ ID NO. 5050;RNA;Artificial Sequence> ugugcugugggcgggcuga
<SEQ ID NO.5051;RNA;Artificial Sequence> agcgugguggccacuggua
<SEQ ID NO. 5052;RNA;Artificial Sequence> acaaggagggcagucgccu
<SEQ ID NO. 5053;RNA;Artificial Sequence> uggcaccugcuggccgugu
<SEQ ID NO. 5054;RNA;Artificial Sequence> uacggggcuggaggggccg
<SEQ ID NO. 5055;RNA;Artificial Sequence> gccuagagauugccagcuu
<SEQ ID NO. 5056;RNA;Artificial Sequence> uccuaccugaggaugcugg
<SEQ ID NO. 5057;RNA;Artificial Sequence> gccgcuaccucugccuggc
<SEQ ID NO. 5058;RNA;Artificial Sequence> cacgaggcuccaugaucgu
<SEQ ID NO. 5059;RNA;Artificial Sequence> uccugcagaaucucaccuu
<SEQ ID NO. 5060;RNA;Artificial Sequence> ugauuacaggugacuccuu
<SEQ ID NO. 5061;RNA;Artificial Sequence> ugaccuccagcaacgauga
<SEQ ID NO. 5062;RNA;Artificial Sequence> augaggaccccaaguccca
<SEQ ID NO. 5063;RNA;Artificial Sequence> auagggaccccucgaauag
<SEQ ID NO. 5064;RNA;Artificial Sequence> ggcacaguuacccccagca
<SEQ ID NO. 5065;RNA;Artificial Sequence> aagcacccuacuggacaca
<SEQ ID NO. 5066;RNA;Artificial Sequence> acccccagcgcauggagaa
<SEQ ID NO. 5067;RNA;Artificial Sequence> agaaacugcaugcaguacc
<SEQ ID NO. 5068;RNA;Artificial Sequence> cugcggggaacaccgucaa
<SEQ ID NO. 5069;RNA;Artificial Sequence> aguuccgcuguccagcugc
<SEQ ID NO. 5070;RNA;Artificial Sequence> caggcaaccccacgcccac
<SEQ ID NO. 5071;RNA;Artificial Sequence> ccauccgcuggcuuaagga
<SEQ ID NO. 5072;RNA;Artificial Sequence> auggacaggccuuucaugg
<SEQ ID NO. 5073;RNA;Artificial Sequence> gggagaaccgcauuggagg
<SEQ ID NO. 5074;RNA;Artificial Sequence> gcauucggcugcgccauca
<SEQ ID NO. 5075;RNA;Artificial Sequence> agcacuggagucucgugau
<SEQ ID NO. 5076;RNA;Artificial Sequence> uggagagcguggugcccuc
<SEQ ID NO. 5077;RNA;Artificial Sequence> cggaccgcggcacauacac
<SEQ ID NO. 5078;RNA;Artificial Sequence> ccugccugguagagaacgc
<SEQ ID NO. 5079;RNA;Artificial Sequence> cugugggcagcauccgcua
<SEQ ID NO. 5080;RNA;Artificial Sequence> auaacuaccugcuagaugu
<SEQ ID NO. 5081;RNA;Artificial Sequence> ugcuggagcgguccccgca
<SEQ ID NO. 5082;RNA;Artificial Sequence> accggcccauccugcaggc
<SEQ ID NO. 5083;RNA;Artificial Sequence> ccgggcucccggccaacac
<SEQ ID NO. 5084;RNA;Artificial Sequence> ccacagccguggugggcag
<SEQ ID NO. 5085;RNA;Artificial Sequence> gcgacguggagcugcugug
<SEQ ID NO. 5086;RNA;Artificial Sequence> gcaagguguacagcgaugc
<SEQ ID NO. 5087;RNA;Artificial Sequence> cccagccccacauccagug
<SEQ ID NO. 5088;RNA;Artificial Sequence> ggcugaagcacaucgucau
<SEQ ID NO. 5089;RNA;Artificial Sequence> ucaacggcagcagcuucgg
<SEQ ID NO. 5090;RNA;Artificial Sequence> gagccgacgguuuccccua
<SEQ ID NO. 5091;RNA;Artificial Sequence> augugcaaguccuaaagac
<SEQ ID NO. 5092;RNA;Artificial Sequence> cugcagacaucaauagcuc
<SEQ ID NO. 5093;RNA;Artificial Sequence> cagagguggagguccugua
<SEQ ID NO. 5094;RNA;Artificial Sequence> accugcggaacgugucagc
<SEQ ID NO. 5095;RNA;Artificial Sequence> ccgaggacgcaggcgagua
<SEQ ID NO. 5096;RNA;Artificial Sequence> acaccugccucgcaggcaa
<SEQ ID NO. 5097;RNA; Artificial Sequence> auuccaucggccucuccua
<SEQ ID NO. 5098;RNA;Artificial Sequence> accagucugccuggcucac
<SEQ ID NO. 5099;RNA;Artificial Sequence> cggugcugccagguacugg
<SEQ ID NO. 5100;RNA;Artificial Sequence> ggcgcaucccccaccucac
<SEQ ID NO. 5101;RNA;Artificial Sequence> caugugacagccugacucc
<SEQ ID NO. 5102;RNA; Artificial Sequence> cagcaggcagaaccaaguc
<SEQ ID NO. 5103;RNA;Artificial Sequence> cucccacuuugcaguucuc
<SEQ ID NO. 5104;RNA; Artificial Sequence> cucgcucccggccgaggagcgcucg
741-3750

CA 02677068 2009-09-01
<SEQ ID NO. 5105;RNA;Artificial Sequence> gggcugucugcggacccugccgcgu
<SEQ ID NO. 5106;RNA;Artificial Sequence> ugcaggggucgcggccggcuggagc
<SEQ ID NO.5107;RNA;Artifcial Sequence> cugggagugaggcggcggaggagcc
<SEQ ID NO. 5108;RNA;Artificial Sequence> caggugaggaggagccaggaaggca
<SEQ ID NO. 5109;RNA; Artificial Sequence> aguuggugggaaguccagcuugggu
<SEQ ID NO. 51 10;RNA;Artificial Sequence> ucccugagagcugugagaaggagau
<SEQ ID NO. 511 1;RNA;Artificial Sequence> ugcggcugcugcuggcccuguuggg
<SEQ ID NO. 5112;RNA;Artificial Sequence> ggguccugcugagugugccugggcc
<SEQ ID NO. 5113;RNA;Artificial Sequence> cuccagucuugucccuggaggccuc
<SEQ ID NO. 5114;RNA;Artificial Sequence> cugaggaaguggagcuugagcccug
<SEQ ID NO. 5115;RNA;Artificial Sequence> gccuggcucccagccuggagcagca
<SEQ ID NO. 5116;RNA;Artificial Sequence> aagagcaggagcugacaguagcccu
<SEQ ID NO. 5117;RNA;Artificial Sequence> uugggcagccugugcgucugugcug
<SEQ ID NO. 5118;RNA; Artificial Sequence> gugggcgggcugagcgugguggcca
<SEQ ID NO. 5119;RNA;Artificial Sequence> acugguacaaggagggcagucgccu
<SEQ ID NO. 5120;RNA;Artificial Sequence> uggcaccugcuggccguguacgggg
<SEQ ID NO. 5121;RNA;Artificial Sequence> gcuggaggggccgccuagagauugc
<SEQ ID NO. 5122;RNA;Artificial Sequence> ccagcuuccuaccugaggaugcugg
<SEQ ID NO. 5123;RNA;Artificial Sequence> gccgcuaccucugccuggcacgagg
<SEQ ID NO. 5124;RNA;Artificial Sequence> gcuccaugaucguccugcagaaucu
<SEQ ID NO.5125;RNA;Artificial Sequence> ucaccuugauuacaggugacuccuu
<SEQ ID NO. 5126;RNA;Artificial Sequence> ugaccuccagcaacgaugaugagga
<SEQ ID NO. 5127;RNA;Artificial Sequence> accccaagucccauagggaccccuc
<SEQ ID NO. 5128;RNA;Artificial Sequence> cgaauaggcacaguuacccccagca
<SEQ ID NO. 5129;RNA;Artificial Sequence> aagcacccuacuggacacaccccca
<SEQ ID NO. 5130;RNA;Artificial Sequence> agcgcauggagaagaaacugcaugc
<SEQ ID NO. 5131;RNA;Artificial Sequence> caguaccugcggggaacaccgucaa
<SEQ ID NO. 5132;RNA;Artificial Sequence> aguuccgcuguccagcugcaggcaa
<SEQ ID NO. 5133;RNA;Artificial Sequence> accccacgcccaccauccgcuggcu
<SEQ ID NO. 5134;RNA;Artificial Sequence> uuaaggauggacaggccuuucaugg
<SEQ ID NO. 5135;RNA;Artificial Sequence> gggagaaccgcauuggaggcauucg
<SEQ ID NO.5136;RNA;Artificial Sequence> ggcugcgccaucagcacuggagucu
<SEQ ID NO. 5137;RNA;Artificial Sequence> ucgugauggagagcguggugcccuc
<SEQ ID NO.5138;RNA;Artificial Sequence> cggaccgcggcacauacaccugccu
<SEQ ID NO. 5139;RNA;Artificial Sequence> ugguagagaacgcugugggcagcau
<SEQ ID NO. 5140;RNA;Artificial Sequence> uccgcuauaacuaccugcuagaugu
<SEQ ID NO. 5141;RNA;Artificial Sequence> ugcuggagcgguccccgcaccggcc
<SEQ ID NO. 5142;RNA;Artificial Sequence> ccauccugcaggccgggcucccggc
<SEQ ID NO. 5143;RNA;Artificial Sequence> ccaacaccacagccguggugggcag
<SEQ ID NO. 5144;RNA;Artificial Sequence> gcgacguggagcugcugugcaaggu
<SEQ ID NO. 5145;RNA;Artificial Sequence> uguacagcgaugcccagccccacau
<SEQ ID NO. 5146;RNA;Artificial Sequence> uccaguggcugaagcacaucgucau
<SEQ ID NO. 5147;RNA;Artificial Sequence> ucaacggcagcagcuucggagccga
<SEQ ID NO.5148;RNA;Artificial Sequence> acgguuuccccuaugugcaaguccu
<SEQ ID NO. 5149;RNA;Artificial Sequence> uaaagacugcagacaucaauagcuc
<SEQ ID NO. 5150;RNA;Artificial Sequence> cagagguggagguccuguaccugcg
<SEQ ID NO.5151;RNA;Artificial Sequence> ggaacgugucagccgaggacgcagg
<SEQ ID NO. 5152;RNA;Artificial Sequence> gcgaguacaccugccucgcaggcaa
<SEQ ID NO. 5153;RNA;Artificial Sequence> auuccaucggccucuccuaccaguc
<SEQ ID NO. 5154;RNA;Artificial Sequence> cugccuggcucacggugcugccaga
<SEQ ID NO. 5155;RNA;Artificial Sequence> aggaggaccccacauggaccgcagc
<SEQ ID NO. 5156;RNA;Artificial Sequence> cagcgcccgaggccagguauacgga
<SEQ ID NO. 5157;RNA;Artificial Sequence> acaucauccuguacgcgucgggcuc
<SEQ ID NO. 5158;RNA;Artificial Sequence> cccuggccuuggcugugcuccugcu
<SEQ ID NO. 5159;RNA;Artificial Sequence> ugcuggccgggcuguaucgagggca
<SEQ ID NO. 5160;RNA;Artificial Sequence> aggcgcuccacggccggcacccccg
<SEQ ID NO. 5161;RNA;Artificial Sequence> gcccgcccgccacugugcagaagcu
<SEQ ID NO. 5162;RNA;Artificial Sequence> ucucccgcuucccucuggcccgaca
<SEQ ID NO. 5163;RNA;Artificial Sequence> aguucucccuggagucaggcucuuc
<SEQ ID NO. 5164;RNA;Artificial Sequence> ccggcaagucaagcucaucccuggu
<SEQ ID NO. 5165;RNA;Artificial Sequence> uacgaggcgugcgucucuccuccag
<SEQ ID NO. 5166;RNA;Artificial Sequence> gcggccccgccuugcucgccggccu
<SEQ ID NO. 5167;RNA;Artificial Sequence> ucgugagucuagaucuaccucucga
<SEQ ID NO. 5168;RNA;Artificial Sequence> acccacuaugggaguucccccggga
<SEQ ID NO. 5169;RNA;Artificial Sequence> acaggcuggugcuugggaagccccu
<SEQ ID NO. 5170;RNA;Artificial Sequence> uaggcgagggcugcuuuggccaggu
<SEQ ID NO.5171;RNA;Artificial Sequence> uaguacgugcagaggccuuuggcau
<SEQ ID NO. 5172;RNA;Artificial Sequence> uggacccugcccggccugaccaagc
<SEQ ID NO. 5173;RNA;Artificial Sequence> ccagcacuguggccgucaagaugcu
<SEQ ID NO. 5174;RNA;Artificial Sequence> ucaaagacaacgccucugacaagga
<SEQ ID NO. 5175;RNA;Artificial Sequence> accuggccgaccuggucucggagau
<SEQ ID NO. 5176;RNA;Artificial Sequence> uggaggugaugaagcugaucggccg
<SEQ ID NO. 5177;RNA;Artificial Sequence> gacacaagaacaucaucaaccugcu
741-3751

CA 02677068 2009-09-01
<SEQ ID NO.5178;RNA;Artificial Sequence> uuggugucugcacccaggaagggcc
<SEQ ID NO. 5179;RNA;Artificial Sequence> cccuguacgugaucguggagugcgc
<SEQ ID NO. 5180;RNA;Artificial Sequence> ccgccaagggaaaccugcgggaguu
<SEQ ID NO. 5181;RNA;Artificial Sequence> uccugcgggcccggcgccccccagg
<SEQ ID NO. 5182;RNA;Artificial Sequence> gccccgaccucagccccgacggucc
<SEQ ID NO. 5183;RNA;Artificial Sequence> cucggagcagugaggggccgcucuc
<SEQ ID NO. 5184;RNA;Artificial Sequence> ccuucccaguccuggucuccugcgc
<SEQ ID NO. 5185;RNA;Artificial Sequence> ccuaccagguggcccgaggcaugca
<SEQ ID NO. 5186;RNA;Artificial Sequence> aguaucuggagucccggaaguguau
<SEQ ID NO. 5187;RNA;Artificial Sequence> uccaccgggaccuggcugcccgcaa
<SEQ ID NO.5188;RNA;Artificial Sequence> augugcuggugacugaggacaaugu
<SEQ ID NO. 5189;RNA;Artificial Sequence> ugaugaagauugcugacuuugggcu
<SEQ ID NO. 5190;RNA;Artificial Sequence> uggcccgcggcguccaccacauuga
<SEQ ID NO. 5191;RNA;Artificial Sequence> acuacuauaagaaaaccagcaacgg
<SEQ ID NO. 5192;RNA;Artificial Sequence> gccgccugccugugaaguggauggc
<SEQ ID NO. 5193;RNA;Artificial Sequence> cgcccgaggccuuguuugaccgggu
<SEQ ID NO. 5194;RNA;Artificial Sequence> uguacacacaccagagugacgugug
<SEQ ID NO. 5195;RNA;Artificial Sequence> ggucuuuugggauccugcuauggga
<SEQ ID NO. 5196;RNA;Artificial Sequence> agaucuucacccucgggggcucccc
<SEQ ID NO. 5197;RNA;Artificial Sequence> cguauccuggcaucccgguggagga
<SEQ ID NO. 5198;RNA;Artificial Sequence> agcuguucucgcugcugcgggaggg
<SEQ ID NO. 5199;RNA;Artificial Sequence> gacaucggauggaccgacccccaca
<SEQ ID NO. 5200;RNA;Artificial Sequence> acugccccccagagcuguacgggcu
<SEQ ID NO.5201;RNA;Artificial Sequence> ugaugcgugagugcuggcacgcagc
<SEQ ID NO. 5202;RNA;Artificial Sequence> cgcccucccagaggccuaccuucaa
<SEQ ID NO. 5203;RNA;Artificial Sequence> agcagcugguggaggcgcuggacaa
<SEQ ID NO.5204;RNA;Artificial Sequence> agguccugcuggccgucucugagga
<SEQ ID NO. 5205;RNA;Artificial Sequence> aguaccucgaccuccgccugaccuu
<SEQ ID NO. 5206;RNA;Artificial Sequence> ucggacccuauucccccucuggugg
<SEQ ID NO. 5207;RNA;Artificial Sequence> gggacgccagcagcaccugcuccuc
<SEQ ID NO. 5208;RNA;Artificial Sequence> ccagcgauucugucuucagccacga
<SEQ ID NO. 5209;RNA;Artificial Sequence> acccccugccauugggauccagcuc
<SEQ ID NO. 5210;RNA;Artificial Sequence> ccuuccccuucgggucuggggugca
<SEQ ID NO. 521 1;RNA;Artificial Sequence> agacaugagcaaggcucaaggcugu
<SEQ ID NO. 5212;RNA;Artificial Sequence> ugcaggcacauaggcugguggccuu
<SEQ ID NO. 5213;RNA;Artificial Sequence> ugggccuuggggcucagccacagcc
<SEQ ID NO. 5214;RNA;Artificial Sequence> cugacacagugcucgaccuugauag
<SEQ ID NO. 5215;RNA;Artificial Sequence> gcauggggccccuggcccagaguug
<SEQ ID NO. 5216;RNA;Artificial Sequence> gcugugccguguccaagggccgugc
<SEQ ID NO. 5217;RNA;Artificial Sequence> cccuugcccuuggagcugccgugcc
<SEQ ID NO. 5218;RNA;Artificial Sequence> cuguguccugauggcccaaauguca
<SEQ ID NO. 5219;RNA;Artificial Sequence> aggguucugcucggcuucuuggacc
<SEQ ID NO. 5220;RNA;Artificial Sequence> cuuggcgcuuaguccccaucccggg
<SEQ ID NO. 5221;RNA;Artificial Sequence> guuuggcugagccuggcuggagagc
<SEQ ID NO. 5222;RNA;Artificial Sequence> cugcuaugcuaaaccuccugccucc
<SEQ ID NO. 5223;RNA;Artificial Sequence> ccaauaccagcaggagguucugggc
<SEQ ID NO. 5224;RNA;Artificial Sequence> ccucugaacccccuuuccccacacc
<SEQ ID NO. 5225;RNA;Artificial Sequence> cucccccugcugcugcugccccagc
<SEQ ID NO. 5226;RNA;Artificial Sequence> cgucuugacgggagcauuggccccu
<SEQ ID NO. 5227;RNA;Artificial Sequence> ugagcccagagaagcuggaagccug
<SEQ ID NO. 5228;RNA;Artificial Sequence> gccgaaaacaggagcaaauggcguu
<SEQ ID NO. 5229;RNA;Artificial Sequence> uuuauaaauuauuuuuuugaaauaa
<SEQ ID NO. 5230;RNA;Artificial Sequence> caggugaggaggagccaggugagca
<SEQ ID NO. 5231;RNA;Artificial Sequence> aggacccugugcugggcgcggaguc
<SEQ ID NO. 5232;RNA;Artificial Sequence> cacgcaggcucgaggaaggcaguug
<SEQ ID NO. 5233;RNA;Artificial Sequence> ggugggaaguccagcuugggucccu
<SEQ ID NO. 5234;RNA;Artificial Sequence> ugagagcugugagaaggagaugcgg
<SEQ ID NO. 5235;RNA; Artificial Sequence> gcugcugcuggcccuguuggggguc
<SEQ ID NO. 5236;RNA;Artificial Sequence> ccugcugagugugccugggccucca
<SEQ ID NO. 5237;RNA;Artificial Sequence> agucuugucccuggaggccucugag
<SEQ ID NO. 5238;RNA;Artificial Sequence> ggaaguggagcuugagcccugccug
<SEQ ID NO. 5239;RNA;Artificial Sequence> ggcucccagccuggagcagcaagag
<SEQ ID NO. 5240;RNA;Artificial Sequence> gcaggagcugacaguagcccuuggg
<SEQ ID NO. 5241;RNA;Artificial Sequence> gcagccugugcgucugugcuguggg
<SEQ ID NO. 5242;RNA;Artificial Sequence> gcgggcugagcgugguggccacugg
<SEQ ID NO. 5243;RNA;Artificial Sequence> guacaaggagggcagucgccuggca
<SEQ ID NO. 5244;RNA;Artificial Sequence> accugcuggccguguacggggcugg
<SEQ ID NO. 5245;RNA;Artificial Sequence> gaggggccgccuagagauugccagc
<SEQ ID NO. 5246;RNA;Artificial Sequence> cuuccuaccugaggaugcuggccgc
<SEQ ID NO. 5247;RNA;Artificial Sequence> cuaccucugccuggcacgaggcucc
<SEQ ID NO. 5248;RNA;Artificial Sequence> caugaucguccugcagaaucucacc
<SEQ ID NO. 5249;RNA;Artificial Sequence> cuugauuacaggugacuccuugacc
<SEQ ID NO.5250;RNA;Artificial Sequence> cuccagcaacgaugaugaggacccc
741-3752

CA 02677068 2009-09-01
<SEQ ID NO. 5251;RNA;Artificial Sequence> caagucccauagggaccccucgaau
<SEQ ID NO. 5252;RNA;Artificial Sequence> uaggcacaguuacccccagcaagca
<SEQ ID NO. 5253;RNA;Artificial Sequence> acccuacuggacacacccccagcgc
<SEQ ID NO. 5254;RNA;Artificial Sequence> cauggagaagaaacugcaugcagua
<SEQ ID NO. 5255;RNA;Artificial Sequence> accugcggggaacaccgucaaguuc
<SEQ ID NO. 5256;RNA;Artificial Sequence> ccgcuguccagcugcaggcaacccc
<SEQ ID NO. 5257;RNA;Artificial Sequence> cacgcccaccauccgcuggcuuaag
<SEQ ID NO. 5258;RNA;Artificial Sequence> ggauggacaggccuuucauggggag
<SEQ ID NO. 5259;RNA;Artificial Sequence> gaaccgcauuggaggcauucggcug
<SEQ ID NO.5260;RNA;Artificial Sequence> gcgccaucagcacuggagucucgug
<SEQ ID NO.5261;RNA;Artificial Sequence> gauggagagcguggugcccucggac
<SEQ ID NO. 5262;RNA;Artificial Sequence> ccgcggcacauacaccugccuggua
<SEQ ID NO. 5263;RNA; Artificial Sequence> agagaacgcugugggcagcauccgc
<SEQ ID NO. 5264;RNA; Artificial Sequence> cuauaacuaccugcuagaugugcug
<SEQ ID NO. 5265;RNA;Artificial Sequence> ggagcgguccccgcaccggcccauc
<SEQ ID NO. 5266;RNA;Artificial Sequence> ccugcaggccgggcucccggccaac
<SEQ ID NO. 5267;RNA;Artificial Sequence> caccacagccguggugggcagcgac
<SEQ ID NO. 5268;RNA;Artificial Sequence> cguggagcugcugugcaagguguac
<SEQ ID NO. 5269;RNA;Artificial Sequence> cagcgaugcccagccccacauccag
<SEQ ID NO. 5270;RNA;Artificial Sequence> guggcugaagcacaucgucaucaac
<SEQ ID NO. 5271;RNA;Artificial Sequence> cggcagcagcuucggagccgacggu
<SEQ ID NO. 5272;RNA;Artificial Sequence> uuuccccuaugugcaaguccuaaag
<SEQ ID NO. 5273;RNA;Artificial Sequence> gacugcagacaucaauagcucagag
<SEQ ID NO. 5274;RNA;Artificial Sequence> gguggagguccuguaccugcggaac
<SEQ ID NO. 5275;RNA;Artificial Sequence> cgugucagccgaggacgcaggcgag
<SEQ ID NO. 5276;RNA;Artificial Sequence> guacaccugccucgcaggcaauucc
<SEQ ID NO. 5277;RNA;Artificial Sequence> caucggccucuccuaccagucugcc
<SEQ ID NO. 5278;RNA;Artificial Sequence> cuggcucacggugcugccagaggag
<SEQ ID NO. 5279;RNA;Artificial Sequence> ggaccccacauggaccgcagcagcg
<SEQ ID NO. 5280;RNA;Artificial Sequence> gcccgaggccagguauacggacauc
<SEQ ID NO. 5281;RNA;Artificial Sequence> cauccuguacgcgucgggcucccug
<SEQ ID NO. 5282;RNA;Artificial Sequence> ggccuuggcugugcuccugcugcug
<SEQ ID NO.5283;RNA;Artificial Sequence> ggccgggcuguaucgagggcaggcg
<SEQ ID NO. 5284;RNA;Artificial Sequence> gcuccacggccggcacccccgcccg
<SEQ ID NO. 5285;RNA;Artificial Sequence> gcccgccacugugcagaagcucucc
<SEQ ID NO. 5286;RNA;Artificial Sequence> ccgcuucccucuggcccgacaguuc
<SEQ ID NO. 5287;RNA;Artificial Sequence> cucccuggagucaggcucuuccggc
<SEQ ID NO. 5288;RNA;Artificial Sequence> caagucaagcucaucccugguacga
<SEQ ID NO. 5289;RNA;Artificial Sequence> aggcgugcgucucuccuccagcggc
<SEQ ID NO. 5290;RNA;Artificial Sequence> ccccgccuugcucgccggccucgug
<SEQ ID NO. 5291;RNA;Artificial Sequence> gagucuagaucuaccucucgaccca
<SEQ ID NO. 5292;RNA;Artificial Sequence> acuaugggaguucccccgggacagg
<SEQ ID NO. 5293;RNA;Artificial Sequence> gcuggugcuugggaagccccuaggc
<SEQ ID NO. 5294;RNA;Artificial Sequence> cgagggcugcuuuggccagguagua
<SEQ ID NO.5295;RNA;Artificial Sequence> acgugcagaggccuuuggcauggac
<SEQ ID NO. 5296;RNA;Artificial Sequence> cccugcccggccugaccaagccagc
<SEQ ID NO. 5297;RNA;Artificial Sequence> cacuguggccgucaagaugcucaaa
<SEQ ID NO. 5298;RNA;Artificial Sequence> agacaacgccucugacaaggaccug
<SEQ ID NO. 5299;RNA;Artificial Sequence> ggccgaccuggucucggagauggag
<SEQ ID NO. 5300;RNA;Artificial Sequence> ggugaugaagcugaucggccgacac
<SEQ ID NO. 5301;RNA;Artificial Sequence> caagaacaucaucaaccugcuuggu
<SEQ ID NO. 5302;RNA;Artificial Sequence> ugucugcacccaggaagggccccug
<SEQ ID NO. 5303;RNA;Artificial Sequence> guacgugaucguggagugcgccgcc
<SEQ ID NO. 5304;RNA;Artificial Sequence> caagggaaaccugcgggaguuccug
<SEQ ID NO. 5305;RNA;Artificial Sequence> gcgggcccggcgccccccaggcccc
<SEQ ID NO. 5306;RNA;Artificial Sequence> cgaccucagccccgacgguccucgg
<SEQ ID NO. 5307;RNA;Artificial Sequence> gagcagugaggggccgcucuccuuc
<SEQ ID NO. 5308;RNA;Artificial Sequence> cccaguccuggucuccugcgccuac
<SEQ ID NO. 5309;RNA;Artificial Sequence> ccagguggcccgaggcaugcaguau
<SEQ ID NO. 5310;RNA;Artificial Sequence> ucuggagucccggaaguguauccac
<SEQ ID NO. 5311;RNA;Artificial Sequence> ccgggaccuggcugcccgcaaugug
<SEQ ID NO. 5312;RNA;Artificial Sequence> gcuggugacugaggacaaugugaug
<SEQ ID NO. 5313;RNA;Artificial Sequence> gaagauugcugacuuugggcuggcc
<SEQ ID NO. 5314;RNA;Artificial Sequence> ccgcggcguccaccacauugacuac
<SEQ ID NO. 5315;RNA;Artificial Sequence> cuauaagaaaaccagcaacggccgc
<SEQ ID NO. 5316;RNA;Artificial Sequence> ccugccugugaaguggauggcgccc
<SEQ ID NO. 5317;RNA;Artificial Sequence> cgaggccuuguuugaccggguguac
<SEQ ID NO. 5318;RNA;Artificial Sequence> cacacaccagagugacguguggucu
<SEQ ID NO. 5319;RNA;Artificial Sequence> uuuugggauccugcuaugggagauc
<SEQ ID NO. 5320;RNA;Artificial Sequence> cuucacccucgggggcuccccguau
<SEQ ID NO. 5321;RNA;Artificial Sequence> uccuggcaucccgguggaggagcug
<SEQ ID NO. 5322;RNA;Artificial Sequence> guucucgcugcugcgggagggacau
<SEQ ID NO. 5 323;RNA; Artificial Sequence> ucggauggaccgacccccacacugc
741-3753

CA 02677068 2009-09-01
<SEQ ID NO. 5324;RNA;Artificial Sequence> ccccccagagcuguacgggcugaug
<SEQ ID NO. 5325;RNA;Artificial Sequence> gcgugagugcuggcacgcagcgccc
<SEQ ID NO. 5326;RNA;Artificial Sequence> cucccagaggccuaccuucaagcag
<SEQ ID NO. 5327;RNA;Artificial Sequence> gcugguggaggcgcuggacaagguc
<SEQ ID NO. 5328;RNA;Artificial Sequence> ccugcuggccgucucugaggaguac
<SEQ ID NO. 5329;RNA;Artificial Sequence> ccucgaccuccgccugaccuucgga
<SEQ ID NO. 5330;RNA;Artificial Sequence> acccuauucccccucugguggggac
<SEQ ID NO.5331;RNA;Artificial Sequence> cgccagcagcaccugcuccuccagc
<SEQ ID NO. 5332;RNA;Artificial Sequence> cgauucugucuucagccacgacccc
<SEQ ID NO. 5333;RNA;Artificial Sequence> ccugccauugggauccagcuccuuc
<SEQ ID NO.5334;RNA;Artificial Sequence> ccccuucgggucuggggugcagaca
<SEQ ID NO. 5335;RNA;Artificial Sequence> augagcaaggcucaaggcugugcag
<SEQ ID NO. 5336;RNA;Artificial Sequence> ggcacauaggcugguggccuugggc
<SEQ ID NO. 5337;RNA;Artificial Sequence> ccuuggggcucagccacagccugac
<SEQ ID NO. 5 33 8;RNA; Artificial Sequence> cacagugcucgaccuugauagcaug
<SEQ ID NO. 5 339;RNA; Artificial Sequence> ggggccccuggcccagaguugcugu
<SEQ ID NO. 5340;RNA;Artificial Sequence> ugccguguccaagggccgugcccuu
<SEQ ID NO. 5341;RNA;Artificial Sequence> ugcccuuggagcugccgugccugug
<SEQ ID NO.5342;RNA;Artificial Sequence> guccugauggcccaaaugucagggu
<SEQ ID NO. 5343;RNA;Artificial Sequence> uucugcucggcuucuuggaccuugg
<SEQ ID NO. 5344;RNA;Artificial Sequence> gcgcuuaguccccaucccggguuug
<SEQ ID NO. 5345;RNA;Artificial Sequence> ggcugagccuggcuggagagcugcu
<SEQ ID NO. 5346;RNA;Artificial Sequence> uaugcuaaaccuccugccucccaau
<SEQ ID NO. 5347;RNA;Artificial Sequence> uaccagcaggagguucugggccucu
<SEQ ID NO. 5348;RNA;Artificial Sequence> ugaacccccuuuccccacaccuccc
<SEQ ID NO. 5349;RNA;Artificial Sequence> cccugcugcugcugccccagcgucu
<SEQ ID NO. 5350;RNA;Artificial Sequence> uugacgggagcauuggccccugagc
<SEQ ID NO. 5351;RNA;Artificial Sequence> cccagagaagcuggaagccugccga
<SEQ ID NO. 5352;RNA;Artificial Sequence> aaaacaggagcaaauggcguuuuau
<SEQ ID NO. 5353;RNA;Artificial Sequence> uaaauuauuuuuuugaaauaaaaaa
<SEQ ID NO. 5354;RNA;Artificial Sequence> gaaggcaguuggugggaaguccagc
<SEQ ID NO. 5355;RNA;Artificial Sequence> cuugggucccugagagcugugagaa
<SEQ ID NO.5356;RNA;Artificial Sequence> aggagaugcggcugcugcuggcccu
<SEQ ID NO. 5357;RNA;Artificial Sequence> uguuggggguccugcugagugugcc
<SEQ ID NO. 5358;RNA;Artificial Sequence> cugggccuccagucuugucccugga
<SEQ ID NO. 5359;RNA;Artificial Sequence> aggccucugaggaaguggagcuuga
<SEQ ID NO. 5360;RNA;Artificial Sequence> agcccugccuggcucccagccugga
<SEQ ID NO. 5361;RNA;Artificial Sequence> agcagcaagagcaggagcugacagu
<SEQ ID NO. 5362;RNA;Artificial Sequence> uagcccuugggcagccugugcgucu
<SEQ ID NO. 5363;RNA;Artificial Sequence> ugugcugugggcgggcugagcgugg
<SEQ ID NO. 5364;RNA;Artificial Sequence> guggccacugguacaaggagggcag
<SEQ ID NO. 5365;RNA;Artificial Sequence> gucgccuggcaccugcuggccgugu
<SEQ ID NO. 5 366;RNA; Artificial Sequence> uacggggcuggaggggccgccuaga
<SEQ ID NO. 5367;RNA;Artificial Sequence> agauugccagcuuccuaccugagga
<SEQ ID NO.5368;RNA;Artificial Sequence> augcuggccgcuaccucugccuggc
<SEQ ID NO. 5369;RNA; Artificial Sequence> cacgaggcuccaugaucguccugca
<SEQ ID NO. 5370;RNA;Artificial Sequence> agaaucucaccuugauuacagguga
<SEQ ID NO. 5371;RNA;Artificial Sequence> acuccuugaccuccagcaacgauga
<SEQ ID NO. 5372;RNA;Artificial Sequence> augaggaccccaagucccauaggga
<SEQ ID NO. 5373;RNA;Artificial Sequence> accccucgaauaggcacaguuaccc
<SEQ ID NO. 5374;RNA;Artificial Sequence> cccagcaagcacccuacuggacaca
<SEQ ID NO. 5375;RNA;Artificial Sequence> acccccagcgcauggagaagaaacu
<SEQ ID NO. 5376;RNA;Artificial Sequence> ugcaugcaguaccugcggggaacac
<SEQ ID NO. 5377;RNA;Artificial Sequence> ccgucaaguuccgcuguccagcugc
<SEQ ID NO. 5378;RNA;Artificial Sequence> caggcaaccccacgcccaccauccg
<SEQ ID NO. 5379;RNA;Artificial Sequence> gcuggcuuaaggauggacaggccuu
<SEQ ID NO. 5380;RNA;Artificial Sequence> uucauggggagaaccgcauuggagg
<SEQ ID NO. 5381;RNA;Artificial Sequence> gcauucggcugcgccaucagcacug
<SEQ ID NO. 5382;RNA;Artificial Sequence> ggagucucgugauggagagcguggu
<SEQ ID NO. 5 383;RNA; Artificial Sequence> ugcccucggaccgcggcacauacac
<SEQ ID NO. 5384;RNA;Artificial Sequence> ccugccugguagagaacgcuguggg
<SEQ ID NO. 5385;RNA;Artificial Sequence> gcagcauccgcuauaacuaccugcu
<SEQ ID NO. 5386;RNA;Artificial Sequence> uagaugugcuggagcgguccccgca
<SEQ ID NO. 5387;RNA;Artificial Sequence> accggcccauccugcaggccgggcu
<SEQ ID NO. 5388;RNA;Artificial Sequence> ucccggccaacaccacagccguggu
<SEQ ID NO. 5 389;RNA; Artificial Sequence> ugggcagcgacguggagcugcugug
<SEQ ID NO. 5390;RNA;Artificial Sequence> gcaagguguacagcgaugcccagcc
<SEQ ID NO. 5391;RNA;Artificial Sequence> cccacauccaguggcugaagcacau
<SEQ ID NO. 5392;RNA; Artificial Sequence> ucgucaucaacggcagcagcuucgg
<SEQ ID NO. 5393;RNA;Artificial Sequence> gagccgacgguuuccccuaugugca
<SEQ ID NO. 5394;RNA; Artificial Sequence> aaguccuaaagacugcagacaucaa
<SEQ ID NO. 5395;RNA;Artificial Sequence> auagcucagagguggagguccugua
<SEQ ID NO. 5396;RNA;Artificial Sequence> accugcggaacgugucagccgagga
741-3754

CA 02677068 2009-09-01
<SEQ ID NO. 5397;RNA;Artificial Sequence> acgcaggcgaguacaccugccucgc
<SEQ ID NO. 5398;RNA;Artificial Sequence> caggcaauuccaucggccucuccua
<SEQ ID NO. 5399;RNA;Artificial Sequence> accagucugccuggcucacggugcu
<SEQ ID NO. 5400;RNA;Artificial Sequence> ugccagguacugggcgcauccccca
<SEQ ID NO.5401;RNA;Artificial Sequence> accucacaugugacagccugacucc
<SEQ ID NO. 5402;RNA;Artificial Sequence> cagcaggcagaaccaagucucccac
<SEQ ID NO. 5403;RNA;Artificial Sequence> cuuugcaguucucccuggagucagg
<SEQ ID NO. 5404;RNA; Artificial Sequence> gcucuuccggcaagucaagcucauc
<SEQ ID NO. 5405;RNA;Artificial Sequence> cccugguacgaggcgugcgucucuc
<SEQ ID NO. 5406;RNA;Artificial Sequence> ccuccagcggccccgccuugcucgc
<SEQ ID NO. 5407;RNA;Artificial Sequence> ccggccucgugagucuagaucuacc
<SEQ ID NO. 5408;RNA;Artificial Sequence> cucucgacccacuaugggaguuccc
<SEQ ID NO. 5409;RNA;Artificial Sequence> cccgggacaggcuggugcuugggaa
<SEQ ID NO. 5410;RNA;Artificial Sequence> agccccuaggcgagggcugcuuugg
<SEQ ID NO. 5411;RNA;Artificial Sequence> gccagguaguacgugcagaggccuu
<SEQ ID NO.5412;RNA;Artificial Sequence> uuggcauggacccugcccggccuga
<SEQ ID NO. 5413;RNA;Artificial Sequence> accaagccagcacuguggccgucaa
<SEQ ID NO. 5414;RNA;Artificial Sequence> agaugcucaaagacaacgccucuga
<SEQ ID NO. 5415;RNA;Artificial Sequence> acaaggaccuggccgaccuggucuc
<SEQ ID NO. 5416;RNA;Artificial Sequence> cggagauggaggugaugaagcugau
<SEQ ID NO. 5417;RNA;Artificial Sequence> ucggccgacacaagaacaucaucaa
<SEQ ID NO. 5418;RNA;Artificial Sequence> accugcuuggugucugcacccagga
<SEQ ID NO.5419;RNA;Artificial Sequence> aagggccccuguacgugaucgugga
<SEQ ID NO. 5420;RNA;Artificial Sequence> agugcgccgccaagggaaaccugcg
<SEQ ID NO. 5421;RNA;Artificial Sequence> gggaguuccugcgggcccggcgccc
<SEQ ID NO. 5422;RNA;Artificial Sequence> ccccaggccccgaccucagccccga
<SEQ ID NO. 5423;RNA;Artificial Sequence> acgguccucggagcagugaggggcc
<SEQ ID NO. 5424;RNA;Artificial Sequence> cgcucuccuucccaguccuggucuc
<SEQ ID NO. 5425;RNA;Artificial Sequence> ccugcgccuaccagguggcccgagg
<SEQ ID NO. 5426;RNA;Artificial Sequence> gcaugcaguaucuggagucccggaa
<SEQ ID NO. 5427;RNA;Artificial Sequence> aguguauccaccgggaccuggcugc
<SEQ ID NO. 5428;RNA;Artificial Sequence> cccgcaaugugcuggugacugagga
<SEQ ID NO. 5429;RNA;Artificial Sequence> acaaugugaugaagauugcugacuu
<SEQ ID NO. 5430;RNA;Artificial Sequence> uugggcuggcccgcggcguccacca
<SEQ ID NO. 5431;RNA;Artificial Sequence> acauugacuacuauaagaaaaccag
<SEQ ID NO. 5432;RNA;Artificial Sequence> gcaacggccgccugccugugaagug
<SEQ ID NO. 5433;RNA; Artificial Sequence> ggauggcgcccgaggccuuguuuga
<SEQ ID NO. 5434;RNA;Artificial Sequence> accggguguacacacaccagaguga
<SEQ ID NO. 5435;RNA;Artificial Sequence> acguguggucuuuugggauccugcu
<SEQ ID NO. 5436;RNA;Artificial Sequence> uaugggagaucuucacccucggggg
<SEQ ID NO. 5437;RNA;Artificial Sequence> gcuccccguauccuggcaucccggu
<SEQ ID NO. 5438;RNA;Artificial Sequence> uggaggagcuguucucgcugcugcg
<SEQ ID NO. 5439;RNA;Artificial Sequence> gggagggacaucggauggaccgacc
<SEQ ID NO. 5440;RNA;Artificial Sequence> ccccacacugccccccagagcugua
<SEQ ID NO. 5441;RNA;Artificial Sequence> acgggcugaugcgugagugcuggca
<SEQ ID NO. 5442;RNA;Artificial Sequence> acgcagcgcccucccagaggccuac
<SEQ ID NO. 5443;RNA;Artificial Sequence> ccuucaagcagcugguggaggcgcu
<SEQ ID NO. 5444;RNA;Artificial Sequence> uggacaagguccugcuggccgucuc
<SEQ ID NO. 5445;RNA;Artificial Sequence> cugaggaguaccucgaccuccgccu
<SEQ ID NO. 5446;RNA;Artificial Sequence> ugaccuucggacccuauucccccuc
<SEQ ID NO. 5447;RNA;Artificial Sequence> cugguggggacgccagcagcaccug
<SEQ ID NO. 5448;RNA;Artificial Sequence> gcuccuccagcgauucugucuucag
<SEQ ID NO. 5449;RNA;Artificial Sequence> gccacgacccccugccauugggauc
<SEQ ID NO. 5450;RNA;Artificial Sequence> ccagcuccuuccccuucgggucugg
<SEQ ID NO. 5451;RNA;Artificial Sequence> gggugcagacaugagcaaggcucaa
<SEQ ID NO. 5452;RNA;Artificial Sequence> aggcugugcaggcacauaggcuggu
<SEQ ID NO. 5453;RNA;Artificial Sequence> uggccuugggccuuggggcucagcc
<SEQ ID NO. 5454;RNA; Artificial Sequence> cacagccugacacagugcucgaccu
<SEQ ID NO. 5455;RNA;Artificial Sequence> uugauagcauggggccccuggccca
<SEQ ID NO. 5456;RNA;Artificial Sequence> agaguugcugugccguguccaaggg
<SEQ ID NO. 5457;RNA;Artificial Sequence> gccgugcccuugcccuuggagcugc
<SEQ ID NO. 5458;RNA;Artificial Sequence> ccgugccuguguccugauggcccaa
<SEQ ID NO. 5459;RNA;Artificial Sequence> aaugucaggguucugcucggcuucu
<SEQ ID NO. 5460;RNA;Artificial Sequence> uuggaccuuggcgcuuaguccccau
<SEQ ID NO. 5461;RNA;Artificial Sequence> ucccggguuuggcugagccuggcug
<SEQ ID NO. 5462;RNA; Artificial Sequence> ggagagcugcuaugcuaaaccuccu
<SEQ ID NO. 5463;RNA;Artificial Sequence> ugccucccaauaccagcaggagguu
<SEQ ID NO. 5464;RNA;Artificial Sequence> ucugggccucugaacccccuuuccc
<SEQ ID NO. 5465;RNA;Artificial Sequence> ccacaccucccccugcugcugcugc
<SEQ ID NO. 5466;RNA;Artificial Sequence> ccccagcgucuugacgggagcauug
<SEQ ID NO. 5467;RNA;Artificial Sequence> ggccccugagcccagagaagcugga
<SEQ ID NO. 5468;RNA;Artificial Sequence> aagccugccgaaaacaggagcaaau
<SEQ ID NO. 5469;RNA; Artificial Sequence> uggcguuuuauaaauuauuuuuuug
741-3755

CA 02677068 2009-09-01
R122 - 1511
<120> NUCLEIC ACID COMPOUNDS FOR INHIBITING
MAPK3 GENE EXPRESSION AND USES THEREOF
<130> 07-R122PCT
<210> 1
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 1
cuacacaaau cagcgauuut t 21
<210> 2
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 2
aaaucgcuga uuuguguagt t 21
<210> 3
<211> 25
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 3
cuacacaaau cagcgauuuc caugt 25
<210> 4
<211> 27
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 4
acauggaaau cgcugauuug uguaguc 27
<210> 5
<211> 13
<212> RNA
<213> Artificial Sequence
741-3756

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 5
cuacacaaau cag 13
<210> 6
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 6
gauuuccaugt 11
<210> 7
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 7
ggaucuuauu ucuucggagt t 21
<210> 8
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 8
cuccgaagaa auaagaucct t 21
<210> 9
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 9
ggaucuuauu u 11
<210> 10
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
741-3757

CA 02677068 2009-09-01
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 10
cuucggagtt 10
<210> 11
<211> 27
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 11
cauugucucc gaagaaauaa gauccuu 27
<210> 12
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 12
ggaucuua 8
<210> 13
<211> 17
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 13
uuucuucgga gacaatg 17
<210> 14
<211> 16
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 14
uucuucggag acaatg 16
<210> 15
<211> 15
741-3758

CA 02677068 2009-09-01
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 15
ucuucggaga caatg 15
<210> 16
<211> 14
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 16
cuucggagac aatg 14
<210> 17
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 17
uucggagaca atg 13
<210> 18
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 18
ucggagacaatg 12
<210> 19
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3759

CA 02677068 2009-09-01
<400> 19
cggagacaat g 11
<210> 20
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 20
ggaucuuau 9
<210> 21
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 21
ggaucuuauu 10
<210> 22
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 22
ggaucuuauu u 11
<210> 23
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222>(2)
<223> LNA-G
<400> 23
ggaucuuauu uc 12
741-3760

CA 02677068 2009-09-01
<210> 24
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 24
cuacacaa 8
<210> 25
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (8)
<223> LNA-A
<400> 25
aucagcgauu utt 13
<210> 26
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-A
<400> 26
ucagcgauuutt 12
<210> 27
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-A
<400> 27
cagcgauuutt 11
<210> 28
<211> 10
<212> DNA
<213> Artificial Sequence
741-3761

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (5) <223> LNA-A
<400> 28
agcgauuutt 10
<210> 29
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (4) <223> LNA-A
<400> 29
gcgauuutt 9
<210> 30
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 30
cgauuutt 8
<210> 31
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-A
<400> 31
gauuutt 7
<210> 32
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
741-3762

CA 02677068 2009-09-01
<222> (3)
<223> LNA-A
<400> 32
cuacacaaa 9
<210> 33
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (3) <223> LNA-A
<400> 33
cuacacaaau 10
<210> 34
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 34
cuacacaaau c 11
<210> 35
<211> 12
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified-base
<222> (3) <223> LNA-A
<400> 35
cuacacaaau ca 12
<210> 36
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 36
cuacacaaau cag 13
741-3763

CA 02677068 2009-09-01
<210> 37
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-A
<400> 37
cuacacaaau cagc 14
<210> 38
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 38
ggaucuuauu ucu 13
<210> 39
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 39
ggaucuuauu ucuu 14
<210> 40
<211> 8
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (8) <223> LNA-A
<400> 40
ggaucuua 8
741-3764

CA 02677068 2009-09-01
<210> 41
<211> 9
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (9)
<223> LNA-U
<400> 41
ggaucuuau 9
<210> 42
<211> 10
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (10)
<223> LNA-U
<400> 42
ggaucuuauu 10
<210> 43
<211> 11
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified base
<222> (11)
<223> LNA-U
<400> 43
ggaucuuauu u I1
<210> 44
<211> 12
<212> RNA
<213> Artificial Sequence
741-3765

CA 02677068 2009-09-01
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (12)
<223> LNA-C
<400> 44
ggaucuuauu uc 12
<210> 45
<211> 13
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (13) <223> LNA-U
<400> 45
ggaucuuauu ucu 13
<210> 46
<211> 14
<212> RNA
<213> Artificial Sequence
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (14)
<223> LNA-U
<400> 46
ggaucuuauu ucuu 14
<210> 47
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNAIRNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3766

CA 02677068 2009-09-01
<220>
<221> modified base
<222> (8)
<223> LNA-G
<400> 47
uuucuucgga gtt 13
<210> 48
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 48
uucuucggag tt 12
<210> 49
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (6)
<223> LNA-G
<400> 49
ucuucggagtt 11
<210> 50
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (5)
<223> LNA-G
<400> 50
cuucggagtt 10
<210> 51
741-3767

CA 02677068 2009-09-01
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (4)
<223> LNA-G
<400> 51
uucggagtt 9
<210> 52
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (3)
<223> LNA-G
<400> 52
ucggagtt 8
<210> 53
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 53
cggagtt 7
<210> 54
<211> 13
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
741-3768

CA 02677068 2009-09-01
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (8)
<223> LNA-G
<400> 54
uuucuucgga gtt 13
<210> 55
<211> 12
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (7)
<223> LNA-G
<400> 55
uucuucggagtt 12
<210> 56
<211> 11
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified-base
<222> (6) <223> LNA-G
<400> 56
ucuucggagtt 11
<210> 57
<211> 10
<212> DNA
<213> Artificial Sequence
<220>
741-3769

CA 02677068 2009-09-01
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-C
<220>
<221> modified base
<222> (5)
<223> LNA-G
<400> 57
cuucggagtt 10
<210> 58
<211> 9
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (4)
<223> LNA-G
<400> 58
uucggagtt 9
<210> 59
<211> 8
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-U
<220>
<221> modified base
<222> (3)
<223> LNA-G
<400> 59
ucggagtt 8
<210> 60
741-3770

CA 02677068 2009-09-01
<211> 7
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (1)
<223> LNA-C
<220>
<221> modified base
<222> (2)
<223> LNA-G
<400> 60
cggagtt 7
<210> 61
<211> 21
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<220>
<221> modified base
<222> (2)
<223> LNA-G
<220>
<221> modified-base
<222> (16)
<223> LNA-G
<400> 61
ggaucuuauu ucuucggagt t 21
<210> 62
<211> 25
<212> DNA
<213> Artificial Sequence
<220>
<223> Description of Combined DNA/RNA Molecule:
Synthetic oligonucleotide
<220>
<223> Description of Artificial Sequence: Synthetic oligonucleotide
<400> 62
ggaucuuauu ucuucggaga caatg 25
<SEQ ID NO. 63;RNA;Artificial Sequence>guauuuugaugaggaguucacggcc
<SEQ ID NO. 64;RNA;Artificial Sequence>ggcccagaugaucaccaucacacca
<SEQ ID NO. 65;RNA;Artificial Sequence>gggaagaaaacuauccugcggguuu
<SEQ ID NO. 66;RNA;Artificial Sequence>guuuuaauuuauuucauccaguuug
<SEQ ID NO. 67;RNA; Artificial Sequence>acguagggaaauguuaaggacuucu
<SEQ ID NO. 68;RNA;Artificial Sequence>ccaggguuuacccagugggacagag
<SEQ ID NO. 69;RNA;Artificial Sequence>agcaagguuuaaauuuguuauugug
741-3771

CA 02677068 2009-09-01
<SEQ ID NO. 70;RNA;Artificial Sequence>uguauuauguuguucaaaugcauuu
<SEQ ID NO. 71;RNA;Artificial Sequence> uuuuaaucuuugugacaggaaagcc
<SEQ ID NO. 72;RNA;Artificial Sequence>uuaaucuuugugacaggaaagcccu
<SEQ ID NO. 73;RNA;Artificial Sequence>gcugcuuaugucucccagcauggcc
<SEQ ID NO. 74;RNA; Artificial Sequence>aaguguuucagaagcuucucccuga
<SEQ ID NO. 75;RNA;Artificial Sequence>gaccaucaauaaggaagaagcccuu
<SEQ ID NO. 76;RNA;Artificial Sequence>ccaucaauaaggaagaagcccuuca
<SEQ ID NO. 77;RNA;Artificial Sequence>ucaauaaggaagaagcccuucagcg
<SEQ ID NO. 78;RNA;Artificial Sequence>aauaaggaagaagcccuucagcggc
<SEQ ID NO. 79;RNA;Artificial Sequence>aggaagaagcccuucagcggccagu
<SEQ ID NO. 80;RNA;Artificial Sequence>gcauaacuaaaggugaaaagcuccg
<SEQ ID NO. 81;RNA;Artifrcial Sequence>cauaacuaaaggugaaaagcuccgg
<SEQ ID NO. 82;RNA;Artificial Sequence>cuacaucacgccagucaacagucug
<SEQ ID NO. 83;RNA;Artificial Sequence>acuggauuuaagcagaguucaaaag
<SEQ ID NO. 84;RNA;Artificial Sequence>cuggauuuaagcagaguucaaaagc
<SEQ ID NO. 85;RNA;Artificial Sequence>gauuuaagcagaguucaaaagcccu
<SEQ ID NO. 86;RNA;Artificial Sequence>auuuaagcagaguucaaaagcccuu
<SEQ ID NO. 87;RNA;Artificial Sequence>uuaagcagaguucaaaagcccuuca
<SEQ ID NO. 88;RNA;Artificial Sequence>uaagcagaguucaaaagcccuucag
<SEQ ID NO. 89;RNA;Artificial Sequence>agcagaguucaaaagcccuucagcg
<SEQ ID NO. 90;RNA; Artificial Sequence>cucagggucugagugaagccgcucg
<SEQ ID NO.9I;RNA;Artificial Sequence>caagcaacuacaucacgccagucaa
<SEQ ID NO. 92;RNA;Artificial Sequence> aucaauggcagcuucuuggugcgug
<SEQ ID NO. 93;RNA; Artificial Sequence>uuccagcccacauuggauucaucag
<SEQ ID NO. 94;RNA;Artificial Sequence>cagcugagaauguggaauaccuaag
<SEQ ID NO. 95;RNA;Artificial Sequence> aacguaucuccuaauuugaggcuca
<SEQ ID NO. 96;RNA;Artificial Sequence>ccuaaaauaauuucucuacaauugg
<SEQ ID NO. 97;RNA;Artificial Sequence>uggaagauucagcuaguuaggagcc
<SEQ ID NO. 98;RNA;Artificial Sequence>uuaaacucuccuagucaauauccac
<SEQ ID NO. 99;RNA;Artificial Sequence>cagccuacaguuauguucagucaca
<SEQ ID NO. 100;RNA;Artificial Sequence> guuauguucagucacacacacauac
<SEQ ID NO. 101;RNA;Artificial Sequence> cacauacaaaauguuccuuuugcuu
<SEQ ID NO. 102;RNA;Artificial Sequence> uccuuuugcuuuuaaaguaauuuuu
<SEQ ID NO. 103;RNA;Artificial Sequence> ugaccugugaagcaacagucaaugg
<SEQ ID NO. 104;RNA;Artificial Sequence> cuaucucacacaucgacaaaccaau
<SEQ ID NO. 105;RNA;Artificial Sequence> uguccucaauuguacugcuaccacu
<SEQ ID NO. 106;RNA;Artificial Sequence> aaaccguagcuggcaagcggucuua
<SEQ ID NO. 107;RNA;Artificial Sequence> uagcuggcaagcggucuuaccggcu
<SEQ ID NO. 108;RNA;Artificial Sequence> uuguaugguuaaaagauggguuacc
<SEQ ID NO. 109;RNA;Artificial Sequence> ugguuaaaagauggguuaccugcga
<SEQ ID NO. 110;RNA;Artificial Sequence> cagggaauuauacaaucuugcugag
<SEQ ID NO. I l l;RNA;Artificial Sequence> acaaucuugcugagcauaaaacagu
<SEQ ID NO. 112;RNA;Artificial Sequence> ccaauaaugaagaguccuuuauccu
<SEQ ID NO. 113;RNA;Artificial Sequence> acuuuggauguuccaacgcaaguug
<SEQ ID NO. 114;RNA;Artificial Sequence> aaugcuuccacuaaacugaaaccau
<SEQ ID NO. 115;RNA;Artificial Sequence> gagaaaguuugacuuuguuaaauau
<SEQ ID NO. 116;RNA;Artificial Sequence> aaagaacuacuguauauuaaaaguu
<SEQ ID NO. 117;RNA;Artificial Sequence> uuagaaauacggguuuugacuuaac
<SEQ ID NO. 118;RNA;Artificial Sequence> aacauggguacagcaaacucagcac
<SEQ ID NO. 119;RNA;Artificial Sequence> aaagacacagaagaugcugaccuca
<SEQ ID NO. 120;RNA;Artifrcial Sequence> uaguagggagguuuauucagaucgc
<SEQ ID NO. 121;RNA;Artificial Sequence> gccuucugcagcaggguucugggau
<SEQ ID NO. 122;RNA;Artificial Sequence> ggucugguacauauuggaaauuaug
<SEQ ID NO. 123;RNA;Artificial Sequence> cuaguccuuccgauggaagcacuag
<SEQ ID NO. 124;RNA;Artificial Sequence> ccagugaauauuguuuuuaugugga
<SEQ ID NO. 125;RNA;Artificial Sequence> augaauucaaguuggaauugguaga
<SEQ ID NO. 126;RNA;Artificial Sequence> caggacacagauuuagacuuggaga
<SEQ ID NO. 127;RNA;Artificial Sequence> cucaaagcacaguuacaguauucca
<SEQ ID NO. 128;RNA;Artificial Sequence> accacugccaccacugaugaauuaa
<SEQ ID NO. 129;RNA;Artificial Sequence> gaaacuacuagugccacaucaucac
<SEQ ID NO. 130;RNA;Artificial Sequence> aagucggacagccucaccaaacaga
<SEQ ID NO. 131;RNA;Artificial Sequence> gaaagcgaaaaauggaacaugaugg
<SEQ ID NO. 132;RNA;Artificial Sequence> cccucugauuuagcauguagacugc
<SEQ ID NO. 133;RNA;Artificial Sequence> ugagcuauuuaaggaucuauuuaug
<SEQ ID NO. 134;RNA;Artificial Sequence> aaaaggugaaaaagcacuauuauca
<SEQ ID NO. 135;RNA;Artificial Sequence> gaaaaagcacuauuaucaguucugc
<SEQ ID NO. 136;RNA;Artificial Sequence> ggcugaaaagaaagauuaaaccuac
<SEQ ID NO. 137;RNA;Artificial Sequence> uaaacccuuauaauaaaauccuucu
<SEQ ID NO. 138;RNA;Artificial Sequence> cauacuauuagccaaugcuguagac
<SEQ ID NO. I39;RNA;Artificial Sequence> gacagaagcauuuugauaggaauag
<SEQ ID NO. 140;RNA;Artificial Sequence> agagcaaauaagauaauggcccuga
<SEQ ID NO. 141;RNA;Artificial Sequence> ccaacauuuuucucuuccucaagca
<SEQ ID NO. 142;RNA;Artificial Sequence> uuaaguaugagaaaaguucagccca
741-3772

CA 02677068 2009-09-01
<SEQ ID NO. 143;RNA;Artificial Sequence> caggaauaaagauggcugcugaacc
<SEQ ID NO. 144;RNA;Artificial Sequence> aauuugaaugaccaaguucucuuca
<SEQ ID NO. 145;RNA;Artificial Sequence> auguauaaagauagccagccuagag
<SEQ ID NO. 146;RNA;Artificial Sequence> ggcuguaacuaucucugugaagugu
<SEQ ID NO. 147;RNA;Artificial Sequence> ucugugaagugugagaaaauuucaa
<SEQ ID NO. 148;RNA;Artificial Sequence> ccuuuaaggaaaugaauccuccuga
<SEQ ID NO. 149;RNA;Artificial Sequence> aaggauacaaaaagugacaucauau
<SEQ ID NO. 150;RNA;Artificial Sequence> agaugcaauuugaaucuucaucaua
<SEQ ID NO. 151;RNA;Artificial Sequence> guucaaaacgaagacuagcuauuaa
<SEQ ID NO. 152;RNA;Artificial Sequence> gugaaaccucaucucuacuaaaaau
<SEQ ID NO. 153;RNA;Artificial Sequence> acgaaagagaagcucuaucucgccu
<SEQ ID NO. I54;RNA;Artificial Sequence> cuccacaagcgccuucgguccaguu
<SEQ ID NO. 155;RNA;Artificial Sequence> gagaagauuccaaagauguagccgc
<SEQ ID NO. 156;RNA;Artificial Sequence> aaucuggauucaaugaggagacuug
<SEQ ID NO. 157;RNA;Artificial Sequence> agaacagauuugagaguagugagga
<SEQ ID NO. 158;RNA;Artificial Sequence> ccagagcugugcagaugaguacaaa
<SEQ ID NO. I59;RNA;Artificial Sequence> ccucagauuguuguuguuaaugggc
<SEQ ID NO. 160;RNA;Artificial Sequence> cuauuuuaauuauuuuuaauuuauu
<SEQ ID NO. 161;RNA;Artificial Sequence> uuuaauuuauuaauauuuaaauaug
<SEQ ID NO. I62;RNA;Artificial Sequence> augcaguuugaauauccuuuguuuc
<SEQ ID NO. 163;RNA;Artificial Sequence> caugcugcuggcgucuaaguguuug
<SEQ ID NO. 164;RNA;Artificial Sequence> agaugugcauuucaccugugacaaa
<SEQ ID NO. 165;RNA;Artificial Sequence> ucaaaaccugugccaggcugaauua
<SEQ ID NO. 166;RNA;Artificial Sequence> gaauguggguagucauucuuacaau
<SEQ ID NO. 167;RNA;Artificial Sequence> auguggguagucauucuuacaauug
<SEQ ID NO. 168;RNA;Artificial Sequence> ugaaaaugagcaucagagaguguac
<SEQ ID NO. 169;RNA;Artificial Sequence> uugcuuuucauguagaacucagcag
<SEQ ID NO. 170;RNA;Artificial Sequence> uguauuucuauauuuauuuucagua
<SEQ ID NO. 171;RNA;Artificial Sequence> uuugauuaauguuucuuaaauggaa
<SEQ ID NO. 172;RNA;Artificial Sequence> caacguguauagugccuaaaauugu
<SEQ ID NO. 173;RNA;Artificial Sequence> cauauccuuggcuacuaacaucugg
<SEQ ID NO. 174;RNA;Artificial Sequence> uacuaacaucuggagacugugagcu
<SEQ ID NO. 175;RNA;Artificial Sequence> cauaaguugugugcuuuuuauuaau
<SEQ ID NO. 176;RNA;Artificial Sequence> gcaucauuuuggcucuucuuacauu
<SEQ ID NO. 177;RNA;Artificial Sequence> gcucuucuuacauuuguaaaaaugu
<SEQ ID NO. 178;RNA;Artificial Sequence> agauuaggucaucuuaauucauauu
<SEQ ID NO. 179;RNA;Artificial Sequence> auggaauugaaagaacuaaucauga
<SEQ ID NO. 180;RNA;Artificial Sequence> cacacucauuccuucugcucuuggg
<SEQ ID NO. 181;RNA;Artificial Sequence> uguagagguaaccaguagcuuugag
<SEQ ID NO. 182;RNA;Artificial Sequence> caaccacaugccacguaauauuuca
<SEQ ID NO. 183;RNA;Artificial Sequence> ucggaaacaaguuauucucuucacu
<SEQ ID NO. 184;RNA;Artificial Sequence> acucccaauaacuaaugcuaagaaa
<SEQ ID NO. 185;RNA;Artificial Sequence> aaugcuaagaaaugcugaaaaucaa
<SEQ ID NO. 186;RNA;Artificial Sequence> gucuuucucuaaauaugauuacuuu
<SEQ ID NO. 187;RNA;Artificial Sequence> ugaauuucaggcauuuuguucuaca
<SEQ ID NO. 188;RNA;Artificial Sequence> cgauucccucucacccgggacucuc
<SEQ ID NO. 189;RNA;Artificial Sequence> aggaaagugaaccuuuaaaguaaag
<SEQ ID NO. 190;RNA;Artificial Sequence> gaggcugcaugcucuggaagccugg
<SEQ ID NO. 191;RNA;Artificial Sequence> ucucugaacagaaaacaaaagagag
<SEQ ID NO. 192;RNA;Artificial Sequence> aacuuggcuguaaucaguuaugccg
<SEQ ID NO. 193;RNA;Artificial Sequence> agaagccaaaauuaaaagaagucca
<SEQ ID NO. 194;RNA;Artificial Sequence> auuaaaagaaguccaggugagguua
<SEQ ID NO. 195;RNA;Artificial Sequence> gaauccggauuaucgggaagaggac
<SEQ ID NO. 196;RNA;Artificial Sequence> aaugugacaucaaagcaaguauugu
<SEQ ID NO. I97;RNA;Artificial Sequence> caucaaagcaaguauuguagcacuc
<SEQ ID NO. 198;RNA;Artificial Sequence> agagagagaaaacaaaaccacaaau
<SEQ ID NO. 199;RNA;Artificial Sequence> ucgcuguaguauuuaagcccauaca
<SEQ ID NO. 200;RNA;Artificial Sequence> cgcuguaguauuuaagcccauacag
<SEQ ID NO. 201;RNA;Artificial Sequence> auuuaagcccauacagaaaccuucc
<SEQ ID NO. 202;RNA;Artificial Sequence> auuaaaauaaacaugguauaccuac
<SEQ ID NO. 203;RNA;Artificial Sequence> cuguucugaucggccaguuuucgga
<SEQ ID NO.204;RNA;Artificial Sequence> aaauaauuugaacuuuggaacaggg
<SEQ ID NO. 205;RNA;Artificial Sequence> ugcgaccuuaauuuaacuuuccagu
<SEQ ID NO. 206;RNA;Artificial Sequence> cugagaaagcuaaaguuugguuuug
<SEQ ID NO. 207;RNA;Artificial Sequence> aguaaagaugcuacuucccacugua
<SEQ ID NO. 208;RNA;Artificial Sequence> cugcuuaauugcugauaccauauga
<SEQ ID NO. 209;RNA;Artificial Sequence> uaccauaugaaugaaacaugggcug
<SEQ ID NO. 210;RNA;Artificial Sequence> aacuuucuuauccaacuuuuucaua
<SEQ ID NO. 211;RNA;Artificial Sequence> ccuugcaugacaucaugaggccgga
<SEQ ID NO. 212;RNA;Artificial Sequence> ugaauuuguauaugacugcauuugu
<SEQ ID NO. 213;RNA;Artificial Sequence> gaauccuaguagaauguuuacuacc
<SEQ ID NO. 214;RNA;Artificial Sequence> gaaagggaagaauuuuuugaugaaa
<SEQ ID NO. 215;RNA;Artificial Sequence> uaucggcaugccagugugugaauuu
741-3773

CA 02677068 2009-09-01
<SEQ ID NO. 216;RNA;Artificial Sequence> caccucauaguagagcaauguaugu
<SEQ ID NO.217;RNA;Artificial Sequence> ccagaauugccaaagcacauauaua
<SEQ ID NO. 218;RNA;Artificial Sequence> uggugaucuggguaauaguuucucc
<SEQ ID NO. 219;RNA;Artificial Sequence> gaucuggguaauaguuucuccaaau
<SEQ ID NO. 220;RNA;Artificial Sequence> ggaugugaugaauacuuccuagaaa
<SEQ ID NO. 221;RNA;Artificial Sequence> cauuuccacagcuacaccauauaug
<SEQ ID NO. 222;RNA;Artificial Sequence> acagcuacaccauauaugaauggag
<SEQ ID NO. 223;RNA;Artificial Sequence> ugcaguucuuacacgagaagaagau
<SEQ ID NO. 224;RNA;Artificial Sequence> acgagaagaagaucauuuacaggga
<SEQ ID NO.225;RNA;Artificial Sequence> cgagaagaagaucauuuacagggac
<SEQ ID NO. 226;RNA;Artificial Sequence> aagaagaucauuuacagggaccuga
<SEQ ID NO. 227;RNA;Artificial Sequence> agaggaagagguguuugacugcauc
<SEQ ID NO. 228;RNA;Artificial Sequence> gaggaagagguguuugacugcaucg
<SEQ ID NO. 229;RNA;Artificial Sequence> cuacuuugagggcgaguucacaggg
<SEQ ID NO. 230;RNA;Artificial Sequence> agggcaucuccuggcaccucugucc
<SEQ ID NO. 23 1;RNA;Artificial Sequence> ggagugauaugguuugucuuuuuaa
<SEQ ID NO. 232;RNA;Artificial Sequence> gagugauaugguuugucuuuuuaag
<SEQ ID NO. 233;RNA;Artificial Sequence> ugcaguaaagauccuaaagguuguc
<SEQ ID NO. 234;RNA;Artificial Sequence> aguaaagauccuaaagguugucgac
<SEQ ID NO. 235;RNA;Artificial Sequence> ugacaaaggacaaccuggcaauugu
<SEQ ID NO. 236;RNA;Artificial Sequence> gcaauugugacccaguggugcgagg
<SEQ ID NO. 237;RNA;Artificial Sequence> aacaucauccauagagacaugaaau
<SEQ ID NO. 238;RNA;Artificial Sequence> ugaaauccaacaauauauuucucca
<SEQ ID NO. 239;RNA;Artificial Sequence> aacaauauauuucuccaugaaggcu
<SEQ ID NO. 240;RNA;Artificial Sequence> aacaguaaagucacgcuggaguggu
<SEQ ID NO.241;RNA;Artificial Sequence> ugugaagaaaguaaaggaagagagg
<SEQ ID NO. 242;RNA;Artificial Sequence> cuuccgagccauccuugcaucgggc
<SEQ ID NO. 243;RNA;Artificial Sequence> aauggagguugaauauccuacugug
<SEQ ID NO. 244;RNA;Artificial Sequence> ggagguugaauauccuacuguguaa
<SEQ ID NO. 245;RNA;Artificial Sequence> auuuugaguuuucccuuguagugua
<SEQ ID NO. 246;RNA;Artificial Sequence> uauccuguuuguucuuuguugauug
<SEQ ID NO. 247;RNA;Artificial Sequence> ccuguuuguucuuuguugauugaaa
<SEQ ID NO. 248;RNA;Artificial Sequence> cucuacagccuucuuuuucuuccau
<SEQ ID NO.249;RNA;Artificial Sequence> ucuuccauagcuaaucuuccuucua
<SEQ ID NO. 250;RNA;Artificial Sequence> auaaucuuccuguugaaugcuucau
<SEQ ID NO. 25 1;RNA;Artificial Sequence> uaaucuuccuguugaaugcuucaug
<SEQ ID NO. 252;RNA;Artificial Sequence> cuucaugacuugaauucuacuuuga
<SEQ ID NO. 253;RNA;Artificial Sequence> aagagggagagaagcaacuacagac
<SEQ ID NO. 254;RNA;Artificial Sequence> cgucuccuaccagaccaaggucaac
<SEQ ID NO. 255;RNA;Artificial Sequence> gaucaaucggcccgacuaucucgac
<SEQ ID NO. 256;RNA;Artificial Sequence> ggacgaacauccaaccuucccaaac
<SEQ ID NO. 257;RNA;Artificial Sequence> agggucggaacccaagcuuagaacu
<SEQ ID NO.258;RNA;Artificial Sequence> ucggaacccaagcuuagaacuuuaa
<SEQ ID NO. 259;RNA;Artificial Sequence> acccaagcuuagaacuuuaagcaac
<SEQ ID NO. 260;RNA;Artificial Sequence> gaacuuuaagcaacaagaccaccac
<SEQ ID NO.261;RNA;Articial Sequence> acuauucaguggcgagaaauaaagu
<SEQ ID NO. 262;RNA;Artificial Sequence> cuauucaguggcgagaaauaaaguu
<SEQ ID NO. 263;RNA;Artificial Sequence> aaacacagauaacaggaaaugaucc
<SEQ ID NO. 264;RNA;Artificial Sequence> cuuaagaaaagagaagaaaugaaac
<SEQ ID NO. 265;RNA;Artificial Sequence> cugaaggaguguguuuccauccucc
<SEQ ID NO. 266;RNA;Artificial Sequence> ucaccgcgggacugaaaaucuuuga
<SEQ ID NO. 267;RNA;Artificial Sequence> agcagaaauaagcgugccguucagg
<SEQ ID NO. 268;RNA;Artificial Sequence> aagcgugccguucaggguccagaag
<SEQ ID NO. 269;RNA;Artificial Sequence> agaaacagucacucaagacugcuug
<SEQ ID NO. 270;RNA;Artificial Sequence> agaggaagaagguccaugucuuugg
<SEQ ID NO. 271;RNA;Artificial Sequence> uguauucaaaauaugccugaaacac
<SEQ ID NO. 272;RNA;Artificial Sequence> auuuuccucccuuucucuguaccuc
<SEQ ID NO. 273;RNA;Artificial Sequence> caaagaaagauagagcaagacaaga
<SEQ ID NO. 274;RNA;Artificial Sequence> aagaaagauagagcaagacaagaaa
<SEQ ID NO. 275;RNA;Artificial Sequence> gaaagcauuuguuuguacaagaucc
<SEQ ID NO. 276;RNA;Artificial Sequence> ugaguuaaacgaacguacuugcaga
<SEQ ID NO. 277;RNA;Artificial Sequence> acugauacagaacgaucgauacaga
<SEQ ID NO. 278;RNA;Artificial Sequence> auauuauauauauauaaaaauaaau
<SEQ ID NO. 279;RNA;Artificial Sequence> auuauauauauauaaaaauaaauau
<SEQ ID NO. 280;RNA;Artificial Sequence> ucacuggauguauuugacugcugug
<SEQ ID NO. 281;RNA;Artificial Sequence> cagggaagaggaggagaugagagac
<SEQ ID NO. 282;RNA;Artificial Sequence> augaucuuuuuuuugucccacuugg
<SEQ ID NO. 283;RNA;Artificial Sequence> ggccgugaacuccucaucaaaauaccu
<SEQ ID NO. 284;RNA;Artificial Sequence> uggugugauggugaucaucugggccgu
<SEQ ID NO. 285;RNA;Artificial Sequence> aaacccgcaggauaguuuucuucccua
<SEQ ID NO. 286;RNA;Artificial Sequence> caaacuggaugaaauaaauuaaaaccc
<SEQ ID NO. 287;RNA;Artificial Sequence> agaaguccuuaacauuucccuacguga
<SEQ ID NO. 288;RNA;Artificial Sequence> cucugucccacuggguaaacccuggcc
741-3774

CA 02677068 2009-09-01
<SEQ ID NO. 289;RNA;Artificial Sequence> cacaauaacaaauuuaaaccuugcucc
<SEQ ID NO. 290;RNA;Artificial Sequence> aaaugcauuugaacaacauaauacaca
<SEQ ID NO. 291;RNA;Artificial Sequence> ggcuuuccugucacaaagauuaaaaac
<SEQ ID NO. 292;RNA;Artificial Sequence> agggcuuuccugucacaaagauuaaaa
<SEQ ID NO. 293;RNA;Artificial Sequence> ggccaugcugggagacauaagcagcag
<SEQ ID NO. 294;RNA;Artificial Sequence> ucagggagaagcuucugaaacacuucu
<SEQ ID NO. 295;RNA;Artificial Sequence> aagggcuucuuccuuauugauggucag
<SEQ ID NO.296;RNA;Artifcial Sequence> ugaagggcuucuuccuuauugaugguc
<SEQ ID NO.297;RNA;Artificial Sequence> cgcugaagggcuucuuccuuauugaug
<SEQ ID NO. 298;RNA;Artificial Sequence> gccgcugaagggcuucuuccuuauuga
<SEQ ID NO. 299;RNA;Artificial Sequence> acuggccgcugaagggcuucuuccuua
<SEQ ID NO. 300;RNA;Artificial Sequence> cggagcuuuucaccuuuaguuaugcuu
<SEQ ID NO. 301;RNA;Artificial Sequence> ccggagcuuuucaccuuuaguuaugcu
<SEQ ID NO. 302;RNA;Artificial Sequence> cagacuguugacuggcgugauguaguu
<SEQ ID NO. 303;RNA;Artificial Sequence> cuuuugaacucugcuuaaauccagugg
<SEQ ID NO. 304;RNA;Artificial Sequence> gcuuuugaacucugcuuaaauccagug
<SEQ ID NO. 305;RNA;Artificial Sequence> agggcuuuugaacucugcuuaaaucca
<SEQ ID NO. 306;RNA; Artificial Sequence> aagggcuuuugaacucugcuuaaaucc
<SEQ ID NO. 307;RNA; Artificial Sequence> ugaagggcuuuugaacucugcuuaaau
<SEQ ID NO. 308;RNA;Artificial Sequence> cugaagggcuuuugaacucugcuuaaa
<SEQ ID NO. 309;RNA;Artificial Sequence> cgcugaagggcuuuugaacucugcuua
<SEQ ID NO.310;RNA;Artificial Sequence> cgagcggcuucacucagacccugaggc
<SEQ ID NO. 31 1;RNA;Artificial Sequence> uugacuggcgugauguaguugcuuggg
<SEQ ID NO. 312;RNA;Artificial Sequence> cacgcaccaagaagcugccauugaucc
<SEQ ID NO. 313;RNA;Artificial Sequence> cugaugaauccaaugugggcuggaauc
<SEQ ID NO. 314;RNA;Artificial Sequence> cuuagguauuccacauucucagcugug
<SEQ ID NO. 315;RNA;Artificial Sequence> ugagccucaaauuaggagauacguuuu
<SEQ ID NO. 316;RNA;Artificial Sequence> ccaauuguagagaaauuauuuuaggaa
<SEQ ID NO. 317;RNA;Artificial Sequence> ggcuccuaacuagcugaaucuuccaau
<SEQ ID NO. 318;RNA;Artificial Sequence> guggauauugacuaggagaguuuaaaa
<SEQ ID NO. 319;RNA;Artificial Sequence> ugugacugaacauaacuguaggcugaa
<SEQ ID NO. 320;RNA; Artificial Sequence> guaugugugugugacugaacauaacug
<SEQ ID NO. 321;RNA;Artificial Sequence> aagcaaaaggaacauuuuguaugugug
<SEQ ID NO. 322;RNA;Artificial Sequence> aaaaauuacuuuaaaagcaaaaggaac
<SEQ ID NO. 323;RNA;Artificial Sequence> ccauugacuguugcuucacaggucaga
<SEQ ID NO. 324;RNA;Artificial Sequence> auugguuugucgaugugugagauaguu
<SEQ ID NO. 325;RNA;Artificial Sequence> agugguagcaguacaauugaggacaag
<SEQ ID NO. 326;RNA; Artificial Sequence> uaagaccgcuugccagcuacgguuuca
<SEQ ID NO.327;RNA;Artificial Sequence> agccgguaagaccgcuugccagcuacg
<SEQ ID NO. 328;RNA;Artificial Sequence> gguaacccaucuuuuaaccauacaacu
<SEQ ID NO. 329;RNA;Artificial Sequence> ucgcagguaacccaucuuuuaaccaua
<SEQ ID NO. 330;RNA;Artificial Sequence> cucagcaagauuguauaauucccugca
<SEQ ID NO. 331;RNA;Artificial Sequence> acuguuuuaugcucagcaagauuguau
<SEQ ID NO. 332;RNA;Artificial Sequence> aggauaaaggacucuucauuauuggaa
<SEQ ID NO. 333;RNA;Artificial Sequence> caacuugcguuggaacauccaaagugu
<SEQ ID NO. 334;RNA;Artificial Sequence> augguuucaguuuaguggaagcauuua
<SEQ ID NO. 335;RNA;Artificial Sequence> auauuuaacaaagucaaacuuucucac
<SEQ ID NO. 336;RNA;Artificial Sequence> aacuuuuaauauacaguaguucuuuuc
<SEQ ID NO. 337;RNA;Artificial Sequence> guuaagucaaaacccguauuucuaaag
<SEQ ID NO. 338;RNA;Artificial Sequence> gugcugaguuugcuguacccauguuga
<SEQ ID NO. 339;RNA;Artificial Sequence> ugaggucagcaucuucugugucuuuac
<SEQ ID NO. 340;RNA;Artificial Sequence> gcgaucugaauaaaccucccuacuagc
<SEQ ID NO. 341;RNA;Artificial Sequence> aucccagaacccugcugcagaaggcca
<SEQ ID NO. 342;RNA;Artificial Sequence> cauaauuuccaauauguaccagaccuu
<SEQ ID NO. 343;RNA;Artificial Sequence> cuagugcuuccaucggaaggacuaggu
<SEQ ID NO. 344;RNA;Artificial Sequence> uccacauaaaaacaauauucacuggga
<SEQ ID NO. 345;RNA;Artificial Sequence> ucuaccaauuccaacuugaauucauug
<SEQ ID NO. 346;RNA;Artificial Sequence> ucuccaagucuaaaucuguguccugag
<SEQ ID NO. 347;RNA;Artificial Sequence> uggaauacuguaacugugcuuugagga
<SEQ ID NO. 348;RNA;Artificial Sequence> uuaauucaucagugguggcagugguag
<SEQ ID NO. 349;RNA;Artificial Sequence> gugaugauguggcacuaguaguuucuu
<SEQ ID NO. 350;RNA;Artificial Sequence> ucuguuuggugaggcuguccgacuuug
<SEQ ID NO. 351;RNA;Artificial Sequence> ccaucauguuccauuuuucgcuuucuc
<SEQ ID NO. 352;RNA;Artificial Sequence> gcagucuacaugcuaaaucagagggua
<SEQ ID NO. 353;RNA;Artificial Sequence> cauaaauagauccuuaaauagcucaaa
<SEQ ID NO.354;RNA;Artificial Sequence> ugauaauagugcuuuuucaccuuuuuc
<SEQ ID NO. 355;RNA;Artificial Sequence> gcagaacugauaauagugcuuuuucac
<SEQ ID NO. 356;RNA;Artificial Sequence> guagguuuaaucuuucuuuucagccau
<SEQ ID NO. 357;RNA;Artificial Sequence> agaaggauuuuauuauaaggguuuaau
<SEQ ID NO.358;RNA;Artificial Sequence> gucuacagcauuggcuaauaguaugaa
<SEQ ID NO. 359;RNA; Artificial Sequence> cuauuccuaucaaaaugcuucugucua
<SEQ ID NO. 360;RNA;Artificial Sequence> ucagggccauuaucuuauuugcucuau
<SEQ ID NO.361;RNA;Artificial Sequence> ugcuugaggaagagaaaaauguugguc
741-3775

CA 02677068 2009-09-01
<SEQ ID NO. 362;RNA;Artificial Sequence> ugggcugaacuuuucucauacuuaaag
<SEQ ID NO. 363;RNA;Artificial Sequence> gguucagcagccaucuuuauuccugcg
<SEQ ID NO. 364;RNA;Artificial Sequence> ugaagagaacuuggucauucaaauuuc
<SEQ ID NO. 365;RNA;Artificial Sequence> cucuaggcuggcuaucuuuauacauac
<SEQ ID NO. 366;RNA;Artificial Sequence> acacuucacagagauaguuacagccau
<SEQ ID NO. 367;RNA;Artificial Sequence> uugaaauuuucucacacuucacagaga
<SEQ ID NO. 368;RNA;Artificial Sequence> ucaggaggauucauuuccuuaaaggaa
<SEQ ID NO. 369;RNA;Artificial Sequence> auaugaugucacuuuuuguauccuuga
<SEQ ID NO. 370;RNA;Artificial Sequence> uaugaugaagauucaaauugcaucuua
<SEQ ID NO. 371;RNA;Artificial Sequence> uuaauagcuagucuucguuuugaacag
<SEQ ID NO. 372;RNA; Artificial Sequence> auuuuuaguagagaugagguuucacca
<SEQ ID NO. 373;RNA;Artificial Sequence> aggcgagauagagcuucucuuucguuc
<SEQ ID NO. 374;RNA;Artificial Sequence> aacuggaccgaaggcgcuuguggagaa
<SEQ ID NO. 375;RNA;Artificial Sequence> gcggcuacaucuuuggaaucuucuccu
<SEQ ID NO. 376;RNA;Artificial Sequence> caagucuccucauugaauccagauugg
<SEQ ID NO. 377;RNA;Artificial Sequence> uccucacuacucucaaaucuguucugg
<SEQ ID NO. 378;RNA;Artificial Sequence> uuuguacucaucugcacagcucuggcu
<SEQ ID NO. 379;RNA;Artificial Sequence> gcccauuaacaacaacaaucugaggug
<SEQ ID NO. 380;RNA;Artificial Sequence> aauaaauuaaaaauaauuaaaauagug
<SEQ ID NO. 381;RNA;Artificial Sequence> cauauuuaaauauuaauaaauuaaaaa
<SEQ ID NO. 382;RNA;Artificial Sequence> gaaacaaaggauauucaaacugcauag
<SEQ ID NO. 383;RNA;Artificial Sequence> caaacacuuagacgccagcagcauggg
<SEQ ID NO. 384;RNA;Artificial Sequence> uuugucacaggugaaaugcacaucuga
<SEQ ID NO. 385;RNA;Artificial Sequence> uaauucagccuggcacagguuuugauc
<SEQ ID NO. 386;RNA;Artificial Sequence> auuguaagaaugacuacccacauucac
<SEQ ID NO. 387;RNA;Artificial Sequence> caauuguaagaaugacuacccacauuc
<SEQ ID NO. 388;RNA;Artificial Sequence> guacacucucugaugcucauuuucaua
<SEQ ID NO. 389;RNA;Artificial Sequence> cugcugaguucuacaugaaaagcaaau
<SEQ ID NO. 390;RNA;Artificial Sequence> uacugaaaauaaauauagaaauacaac
<SEQ ID NO. 391;RNA;Artificial Sequence> uuccauuuaagaaacauuaaucaaaac
<SEQ ID NO. 392;RNA;Artificial Sequence> acaauuuuaggcacuauacacguuguu
<SEQ ID NO. 393;RNA;Artificial Sequence> ccagauguuaguagccaaggauauggu
<SEQ ID NO. 394;RNA;Artificial Sequence> agcucacagucuccagauguuaguagc
<SEQ ID NO. 395;RNA;Artificial Sequence> auuaauaaaaagcacacaacuuauggc
<SEQ ID NO. 396;RNA;Artificial Sequence> aauguaagaagagccaaaaugaugcau
<SEQ ID NO. 397;RNA;Artificial Sequence> acauuuuuacaaauguaagaagagcca
<SEQ ID NO. 398;RNA;Artificial Sequence> aauaugaauuaagaugaccuaaucugu
<SEQ ID NO. 399;RNA;Artificial Sequence> ucaugauuaguucuuucaauuccaucc
<SEQ ID NO. 400;RNA;Artificial Sequence> cccaagagcagaaggaaugagugugca
<SEQ ID NO. 401;RNA;Artificial Sequence> cucaaagcuacugguuaccucuacacc
<SEQ ID NO. 402;RNA;Artificial Sequence> ugaaauauuacguggcaugugguuggg
<SEQ ID NO. 403;RNA;Artificial Sequence> agugaagagaauaacuuguuuccgaag
<SEQ ID NO. 404;RNA;Artificial Sequence> uuucuuagcauuaguuauugggaguga
<SEQ ID NO. 405;RNA;Artificial Sequence> uugauuuucagcauuucuuagcauuag
<SEQ ID NO. 406;RNA;Artificial Sequence> aaaguaaucauauuuagagaaagacag
<SEQ ID NO. 407;RNA;Artificial Sequence> uguagaacaaaaugccugaaauucagc
<SEQ ID NO. 408;RNA;Artificial Sequence> gagagucccgggugagagggaaucgcc
<SEQ ID NO. 409;RNA;Artificial Sequence> cuuuacuuuaaagguucacuuuccuug
<SEQ ID NO. 410;RNA;Artificial Sequence> ccaggcuuccagagcaugcagccuccu
<SEQ ID NO. 41 1;RNA;Artificial Sequence> cucucuuuuguuuucuguucagagaaa
<SEQ ID NO. 412;RNA;Artificial Sequence> cggcauaacugauuacagccaaguuca
<SEQ ID NO. 413;RNA;Artificial Sequence> uggacuucuuuuaauuuuggcuucuuc
<SEQ ID NO. 414;RNA;Artificial Sequence> uaaccucaccuggacuucuuuuaauuu
<SEQ ID NO. 415;RNA;Artificial Sequence> guccucuucccgauaauccggauucag
<SEQ ID NO. 416;RNA;Artificial Sequence> acaauacuugcuuugaugucacauuaa
<SEQ ID NO. 417;RNA;Artificial Sequence> gagugcuacaauacuugcuuugauguc
<SEQ ID NO. 418;RNA;Artificial Sequence> auuugugguuuuguuuucucucucucu
<SEQ ID NO. 419;RNA;Artificial Sequence> uguaugggcuuaaauacuacagcgagg
<SEQ ID NO. 420;RNA;Artificial Sequence> cuguaugggcuuaaauacuacagcgag
<SEQ ID NO. 421;RNA;Artificial Sequence> ggaagguuucuguaugggcuuaaauac
<SEQ ID NO. 422;RNA; Artificial Sequence> guagguauaccauguuuauuuuaauac
<SEQ ID NO. 423;RNA;Artificial Sequence> uccgaaaacuggccgaucagaacagcc
<SEQ ID NO. 424;RNA;Artificial Sequence> cccuguuccaaaguucaaauuauuugu
<SEQ ID NO. 425;RNA;Artificial Sequence> acuggaaaguuaaauuaaggucgcaau
<SEQ ID NO. 426;RNA;Artificial Sequence> caaaaccaaacuuuagcuuucucagcc
<SEQ ID NO. 427;RNA;Artificial Sequence> uacagugggaaguagcaucuuuacuuu
<SEQ ID NO. 428;RNA;Artificial Sequence> ucauaugguaucagcaauuaagcagua
<SEQ ID NO. 429;RNA;Artificial Sequence> cagcccauguuucauucauaugguauc
<SEQ ID NO. 430;RNA;Artificial Sequence> uaugaaaaaguuggauaagaaaguugg
<SEQ ID NO. 431;RNA;Artificial Sequence> uccggccucaugaugucaugcaaggcu
<SEQ ID NO. 432;RNA;Artificial Sequence> acaaaugcagucauauacaaauucagg
<SEQ ID NO. 433;RNA;Artificial Sequence> gguaguaaacauucuacuaggauucuu
<SEQ ID NO. 434;RNA;Artificial Sequence> uuucaucaaaaaauucuucccuuucug
741-3776

CA 02677068 2009-09-01
<SEQ ID NO. 435;RNA;Artificial Sequence> aaauucacacacuggcaugccgauagc
<SEQ ID NO. 436;RNA;Artificial Sequence> acauacauugcucuacuaugaggugaa
<SEQ ID NO. 437;RNA;Artificial Sequence> uauauaugugcuuuggcaauucuggug
<SEQ ID NO. 438;RNA;Artificial Sequence> ggagaaacuauuacccagaucaccacu
<SEQ ID NO.439;RNA;Artificial Sequence> auuuggagaaacuauuacccagaucac
<SEQ ID NO. 440;RNA;Artificial Sequence> uuucuaggaaguauucaucacauccac
<SEQ ID NO. 441;RNA;Artificial Sequence> cauauaugguguagcuguggaaaugcg
<SEQ ID NO. 442;RNA;Artificial Sequence> cuccauucauauaugguguagcugugg
<SEQ ID NO. 443;RNA;Artificial Sequence> aucuucuucucguguaagaacugcagc
<SEQ ID NO. 444;RNA;Artificial Sequence> ucccuguaaaugaucuucuucucgugu
<SEQ ID NO. 445;RNA;Artificial Sequence> gucccuguaaaugaucuucuucucgug
<SEQ ID NO. 446;RNA;Artificial Sequence> ucaggucccuguaaaugaucuucuucu
<SEQ ID NO. 447;RNA;Artificial Sequence> gaugcagucaaacaccucuuccucugu
<SEQ ID NO. 448;RNA;Artificial Sequence> cgaugcagucaaacaccucuuccucug
<SEQ ID NO. 449;RNA;Artificial Sequence> cccugugaacucgcccucaaaguagcg
<SEQ ID NO. 450;RNA;Artificial Sequence> ggacagaggugccaggagaugcccuca
<SEQ ID NO. 451;RNA;Artificial Sequence> uuaaaaagacaaaccauaucacuccuu
<SEQ ID NO. 452;RNA;Artificial Sequence> cuuaaaaagacaaaccauaucacuccu
<SEQ ID NO. 453;RNA;Artificial Sequence> gacaaccuuuaggaucuuuacugcaac
<SEQ ID NO. 454;RNA; Artificial Sequence> gucgacaaccuuuaggaucuuuacugc
<SEQ ID NO. 455;RNA;Artificial Sequence> acaauugccagguuguccuuugucaug
<SEQ ID NO. 456;RNA;Artificial Sequence> ccucgcaccacugggucacaauugcca
<SEQ ID NO. 457;RNA;Artificial Sequence> auuucaugucucuauggaugauguucu
<SEQ ID NO. 458;RNA;Artificial Sequence> uggagaaauauauuguuggauuucaug
<SEQ ID NO. 459;RNA;Artificial Sequence> agccuucauggagaaauauauuguugg
<SEQ ID NO. 460;RNA;Artificial Sequence> accacuccagcgugacuuuacuguugc
<SEQ ID NO. 461;RNA;Artificial Sequence> ccucucuuccuuuacuuucuucacaca
<SEQ ID NO. 462;RNA;Artificial Sequence> gcccgaugcaaggauggcucggaagcg
<SEQ ID NO. 463;RNA;Artificial Sequence> cacaguaggauauucaaccuccauuuc
<SEQ ID NO. 464;RNA;Artificial Sequence> uuacacaguaggauauucaaccuccau
<SEQ ID NO. 465;RNA;Artificial Sequence> uacacuacaagggaaaacucaaaaucu
<SEQ ID NO.466;RNA;Artificial Sequence> caaucaacaaagaacaaacaggauaaa
<SEQ ID NO. 467;RNA;Artificial Sequence> uuucaaucaacaaagaacaaacaggau
<SEQ ID NO. 468;RNA;Artificial Sequence> auggaagaaaaagaaggcuguagagaa
<SEQ ID NO. 469;RNA;Artificial Sequence> uagaaggaagauuagcuauggaagaaa
<SEQ ID NO. 470;RNA;Artificial Sequence> augaagcauucaacaggaagauuauuu
<SEQ ID NO. 471;RNA;Artificial Sequence> caugaagcauucaacaggaagauuauu
<SEQ ID NO. 472;RNA;Artificial Sequence> ucaaaguagaauucaagucaugaagca
<SEQ ID NO. 473;RNA; Artificial Sequence> gucuguaguugcuucucucccucuuag
<SEQ ID NO. 474;RNA;Artificial Sequence> guugaccuuggucugguaggagacggc
<SEQ ID NO. 475;RNA;Artificial Sequence> gucgagauagucgggccgauugaucuc
<SEQ ID NO. 476;RNA;Artificial Sequence> guuugggaagguuggauguucguccuc
<SEQ ID NO. 477;RNA;Artificial Sequence> aguucuaagcuuggguuccgacccuaa
<SEQ ID NO. 478;RNA;Artificial Sequence> uuaaaguucuaagcuuggguuccgacc
<SEQ ID NO. 479;RNA;Artificial Sequence> guugcuuaaaguucuaagcuuggguuc
<SEQ ID NO.480;RNA;Artificial Sequence> gugguggucuuguugcuuaaaguucua
<SEQ ID NO. 481;RNA;Artificial Sequence> acuuuauuucucgccacugaauaguag
<SEQ ID NO. 482;RNA;Artificial Sequence> aacuuuauuucucgccacugaauagua
<SEQ ID NO. 483;RNA;Artificial Sequence> ggaucauuuccuguuaucuguguuugu
<SEQ ID NO. 484;RNA;Artificial Sequence> guuucauuucuucucuuuucuuaaggc
<SEQ ID NO. 485;RNA;Artificial Sequence> ggaggauggaaacacacuccuucaguu
<SEQ ID NO. 486;RNA;Artificial Sequence> ucaaagauuuucagucccgcggugaca
<SEQ ID NO. 487;RNA;Artificial Sequence> ccugaacggcacgcuuauuucugcugu
<SEQ ID NO. 488;RNA;Artificial Sequence> cuucuggacccugaacggcacgcuuau
<SEQ ID NO. 489;RNA;Artificial Sequence> caagcagucuugagugacuguuucuuc
<SEQ ID NO. 490;RNA;Artificial Sequence> ccaaagacauggaccuucuuccucuga
<SEQ ID NO. 491;RNA;Artificial Sequence> guguuucaggcauauuuugaauacauc
<SEQ ID NO. 492;RNA;Artificial Sequence> gagguacagagaaagggaggaaaauag
<SEQ ID NO. 493;RNA;Artificial Sequence> ucuugucuugcucuaucuuucuuuggu
<SEQ ID NO. 494;RNA;Artificial Sequence> uuucuugucuugcucuaucuuucuuug
<SEQ ID NO. 495;RNA;Artificial Sequence> ggaucuuguacaaacaaaugcuuucuc
<SEQ ID NO. 496;RNA;Artificial Sequence> ucugcaaguacguucguuuaacucaag
<SEQ ID NO. 497;RNA;Artificial Sequence> ucuguaucgaucguucuguaucagucu
<SEQ ID NO. 498;RNA;Artificial Sequence> auuuauuuuuauauauauauaauauau
<SEQ ID NO. 499;RNA;Artificial Sequence> auauuuauuuuuauauauauauaauau
<SEQ ID NO. 500;RNA;Artificial Sequence> cacagcagucaaauacauccagugaag
<SEQ ID NO. 501;RNA;Artificial Sequence> gucucucaucuccuccucuucccuguc
<SEQ ID NO. 502;RNA;Artificial Sequence> ccaagugggacaaaaaaaagaucaugc
<SEQ ID NO. 503;RNA;Artificial Sequence> guauuuugaugagg
<SEQ ID NO. 504;RNA;Artificial Sequence> ggcccagaugau
<SEQ ID NO. 505;RNA;Artificial Sequence> gggaagaaaacuau
<SEQ ID NO. 506;RNA;Artificial Sequence> guuuuaauuuauuuc
<SEQ ID NO.507;RNA;Artificial Sequence> acguagggaaau
741-3777

CA 02677068 2009-09-01
<SEQ ID NO. 508;RNA;Artificial Sequence> ccaggguuuacc
<SEQ ID NO. 509;RNA;Artificial Sequence> agcaagguuua
<SEQ ID NO. 5 10;RNA;Artificial Sequence> uguauuauguug
<SEQ ID NO. 511;RNA;Artificial Sequence> uuuuaaucuuuguga
<SEQ ID NO. 512;RNA;Artificial Sequence> uuaaucuuugugac
<SEQ ID NO. 513;RNA;Artificial Sequence> gcugcuuaugucu
<SEQ ID NO. 514;RNA;Artificial Sequence> aaguguuucagaag
<SEQ ID NO. 515;RNA;Artificial Sequence> gaccaucaauaag
<SEQ ID NO. 516;RNA;Artificial Sequence> ccaucaauaagga
<SEQ ID NO. 517;RNA;Artificial Sequence> ucaauaaggaagaa
<SEQ ID NO. 518;RNA;Artificial Sequence> aauaaggaagaagc
<SEQ ID NO. 519;RNA;Artificial Sequence> aggaagaagcccu
<SEQ ID NO. 520;RNA;Artificial Sequence> gcauaacuaaagg
<SEQ ID NO. 521;RNA;Artificial Sequence> cauaacuaaaggug
<SEQ ID NO. 522;RNA;Artificial Sequence> cuacaucacgcc
<SEQ ID NO. 523;RNA;Artificial Sequence> acuggauuuaag
<SEQ ID NO. 524;RNAArtificial Sequence> cuggauuuaagc
<SEQ ID NO. 525;RNA;Artificial Sequence> gauuuaagcagag
<SEQ ID NO. 526;RNA;Artificial Sequence> auuuaagcagagu
<SEQ ID NO. 527;RNA;Artificial Sequence> uuaagcagaguuc
<SEQ ID NO.528;RNA;Artificial Sequence> uaagcagaguuca
<SEQ ID NO. 529;RNA;Artificial Sequence> agcagaguucaaaa
<SEQ ID NO. 530;RNA;Artificial Sequence> cucagggucuga
<SEQ ID NO. 531;RNA;Artificial Sequence> caagcaacuacau
<SEQ ID NO. 532;RNA;Artificial Sequence> aucaauggcagc
<SEQ ID NO.533;RNA;Artificial Sequence> uuccagcccac
<SEQ ID NO. 534;RNA;Artificial Sequence> cagcugagaaug
<SEQ ID NO. 535;RNA;Artificial Sequence> aacguaucuccua
<SEQ ID NO. 536;RNA;Artificial Sequence> ccuaaaauaauuuc
<SEQ ID NO. 537;RNA;Artificial Sequence> uggaagauucagc
<SEQ ID NO. 538;RNA;Artificial Sequence> uuaaacucuccu
<SEQ ID NO. 539;RNA;Artificial Sequence> cagccuacaguu
<SEQ ID NO. 540;RNA;Artificial Sequence> guuauguucaguc
<SEQ ID NO. 541;RNA;Artificial Sequence> cacauacaaaaug
<SEQ ID NO. 542;RNA;Artificial Sequence> uccuuuugc
<SEQ ID NO. 543;RNA;Artificial Sequence> ugaccugugaag
<SEQ ID NO. 544;RNA;Artificial Sequence> cuaucucacaca
<SEQ ID NO. 545;RNA;Artificial Sequence> uguccucaauugu
<SEQ ID NO. 546;RNA;Artificial Sequence> aaaccguagcug
<SEQ ID NO. 547;RNA;Artificial Sequence> uagcuggcaagc
<SEQ ID NO. 548;RNA;Artificial Sequence> uuguaugguuaaaa
<SEQ ID NO. 549;RNA;Artificial Sequence> ugguuaaaagaugg
<SEQ ID NO. 550;RNA;Artificial Sequence> cagggaauuauac
<SEQ ID NO. 551;RNA;Artificial Sequence> acaaucuugcug
<SEQ ID NO. 552;RNA;Artificial Sequence> ccaauaaugaaga
<SEQ ID NO. 553;RNA;Artificial Sequence> acuuuggauguuc
<SEQ ID NO. 554;RNA;Artificial Sequence> aaugcuuccacu
<SEQ ID NO. 555;RNA;Artificial Sequence> gagaaaguuug
<SEQ ID NO. 556;RNA;Artificial Sequence> aaagaacuacu
<SEQ ID NO.557;RNA;Artificial Sequence> uuagaaauacgg
<SEQ ID NO. 558;RNA;Artificial Sequence> aacauggguaca
<SEQ ID NO. 559;RNA;Artificial Sequence> aaagacacagaaga
<SEQ ID NO. 560;RNA;Artificial Sequence> uaguagggagg
<SEQ ID NO. 561;RNA;Artificial Sequence> gccuucugcagc
<SEQ ID NO. 562;RNA;Artificial Sequence> ggucugguac
<SEQ ID NO. 563;RNA;Artificial Sequence> cuaguccuuccg
<SEQ ID NO. 564;RNA;Artificial Sequence> ccagugaauauu
<SEQ ID NO. 565;RNA;Artificial Sequence> augaauucaaguu
<SEQ ID NO. 566;RNA;Artificial Sequence> caggacacagau
<SEQ ID NO. 567;RNA;Artificial Sequence> cucaaagcacag
<SEQ ID NO. 568;RNA;Artificial Sequence> accacugcca
<SEQ ID NO. 569;RNA;Artificial Sequence> gaaacuacuagug
<SEQ ID NO. 570;RNA;Artificial Sequence> aagucggacagc
<SEQ ID NO. 571;RNA;Artificial Sequence> gaaagcgaaaaau
<SEQ ID NO. 572;RNA;Artificial Sequence> cccucugauuuag
<SEQ ID NO. 573;RNA;Artificial Sequence> ugagcuauuuaa
<SEQ ID NO. 574;RNA;Artificial Sequence> aaaaggugaaaaa
<SEQ ID NO. 575;RNA;Artificial Sequence> gaaaaagcacuauu
<SEQ ID NO. 576;RNA;Artificial Sequence> ggcugaaaagaa
<SEQ ID NO. 577;RNA;Artificial Sequence> uaaacccuuaua
<SEQ ID NO. 578;RNA;Artificial Sequence> cauacuauuagcc
<SEQ ID NO. 579;RNA;Artificial Sequence> gacagaagcauu
<SEQ ID NO. 580;RNA;Artificial Sequence> agagcaaauaagau
741-3778

CA 02677068 2009-09-01
<SEQ ID NO. 581;RNA;Artificial Sequence> ccaacauuuuucuc
<SEQ ID NO. 582;RNA;Artificial Sequence> uuaaguaugagaaaa
<SEQ ID NO. 583;RNA;Artificial Sequence> caggaauaaagaug
<SEQ ID NO. 584;RNA;Artificial Sequence> aauuugaaugacc
<SEQ ID NO. 585;RNA;Artificial Sequence> auguauaaagauag
<SEQ ID NO. 586;RNA;Artificial Sequence> ggcuguaacuau
<SEQ ID NO. 5 87;RNA; Artificial Sequence> ucugugaagug
<SEQ ID NO. 588;RNA;Artificial Sequence> ccuuuaaggaaaug
<SEQ ID NO. 589;RNA;Artificial Sequence> aaggauacaaaaa
<SEQ ID NO. 590;RNA;Artificial Sequence> agaugcaauuug
<SEQ ID NO. 591;RNA;Artificial Sequence> guucaaaacgaa
<SEQ ID NO. 592;RNA;Artificial Sequence> gugaaaccuca
<SEQ ID NO. 593;RNA;Artificial Sequence> acgaaagagaagc
<SEQ ID NO. 594;RNA;Artificial Sequence> cuccacaagcgc
<SEQ ID NO. 595;RNA;Artificial Sequence> gagaagauuccaaa
<SEQ ID NO. 596;RNA;Artificial Sequence> aaucuggauucaa
<SEQ ID NO. 597;RNA;Artificial Sequence> agaacagauuuga
<SEQ ID NO. 598;RNA;Artificial Sequence> ccagagcugug
<SEQ ID NO. 599;RNA;Artificial Sequence> ccucagauuguu
<SEQ ID NO. 600;RNA;Artificial Sequence> cuauuuuaauua
<SEQ ID NO. 601;RNA;Artificial Sequence> uuuaauuuauuaa
<SEQ ID NO. 602;RNA;Artificial Sequence> augcaguuugaa
<SEQ ID NO. 603;RNA;Artificial Sequence> caugcugcugg
<SEQ ID NO. 604;RNA;Artificial Sequence> agaugugcauuuc
<SEQ ID NO. 605;RNA;Artificial Sequence> ucaaaaccugug
<SEQ ID NO. 606;RNA;Artificial Sequence> gaaugugggua
<SEQ ID NO. 607;RNA;Artificial Sequence> auguggguag
<SEQ ID NO. 608;RNA;Artificial Sequence> ugaaaaugagcau
<SEQ ID NO. 609;RNA;Artificial Sequence> uugcuuuucaugu
<SEQ ID NO. 610;RNA;Artificial Sequence> uguauuucuaua
<SEQ ID NO. 61 1;RNA;Artificial Sequence> uuugauuaauguu
<SEQ ID NO. 612;RNA;Artificial Sequence> caacguguauag
<SEQ ID NO. 613;RNA;Artificial Sequence> cauauccuuggc
<SEQ ID NO. 614;RNA;Artificial Sequence> uacuaacaucugg
<SEQ ID NO. 615;RNA;Artificial Sequence> cauaaguugug
<SEQ ID NO. 616;RNA;Artificial Sequence> gcaucauuuugg
<SEQ ID NO. 617;RNA;Artificial Sequence> gcucuucuua
<SEQ ID NO. 618;RNA;Artificial Sequence> agauuagguc
<SEQ ID NO. 619;RNA;Artificial Sequence> auggaauugaaa
<SEQ ID NO. 620;RNA;Artificial Sequence> cacacucauuccu
<SEQ ID NO. 621;RNA;Artificial Sequence> uguagagguaac
<SEQ ID NO. 622;RNA;Artificial Sequence> caaccacaugc
<SEQ ID NO. 623;RNA;Artificial Sequence> ucggaaacaagu
<SEQ ID NO. 624;RNA;Artificial Sequence> acucccaauaa
<SEQ ID NO. 625;RNA;Artificial Sequence> aaugcuaagaaau
<SEQ ID NO. 626;RNA;Artificial Sequence> gucuuucucua
<SEQ ID NO. 627;RNA;Artificial Sequence> ugaauuucagg
<SEQ ID NO. 628;RNA;Artificial Sequence> cgauucccucuca
<SEQ ID NO. 629;RNA;Artificial Sequence> aggaaagugaa
<SEQ ID NO. 630;RNA;Artificial Sequence> gaggcugcaugc
<SEQ ID NO. 631;RNA;Artificial Sequence> ucucugaacag
<SEQ ID NO. 632;RNA;Artificial Sequence> aacuuggcugua
<SEQ ID NO. 633;RNA;Artificial Sequence> agaagccaaaau
<SEQ ID NO. 634;RNA;Artificial Sequence> auuaaaagaagucc
<SEQ ID NO. 635;RNA;Artificial Sequence> gaauccggauuauc
<SEQ ID NO. 636;RNA;Artificial Sequence> aaugugacauca
<SEQ ID NO. 637;RNA;Artificial Sequence> caucaaagcaagu
<SEQ ID NO. 638;RNA;Artificial Sequence> agagagagaaa
<SEQ ID NO. 639;RNA;Artificial Sequence> ucgcuguaguauu
<SEQ ID NO. 640;RNA;Artificial Sequence> cgcuguaguauuua
<SEQ ID NO. 641;RNA;Artificial Sequence> auuuaagcccaua
<SEQ ID NO. 642;RNA;Artificial Sequence> auuaaaauaaacaug
<SEQ ID NO. 643;RNA;Artificial Sequence> cuguucugaucg
<SEQ ID NO. 644;RNA;Artificial Sequence> aaauaauuugaacuuu
<SEQ ID NO. 645;RNA;Artificial Sequence> ugcgaccuuaau
<SEQ ID NO. 646;RNA;Artificial Sequence> cugagaaagcu
<SEQ ID NO.647;RNA;Artificial Sequence> aguaaagaugcua
<SEQ ID NO. 648;RNA;Artificial Sequence> cugcuuaauugc
<SEQ ID NO. 649;RNA;Artificial Sequence> uaccauaugaauga
<SEQ ID NO. 650;RNA;Artificial Sequence> aacuuucuuauc
<SEQ ID NO.651;RNA;Artificial Sequence> ccuugcaugacau
<SEQ ID NO. 652;RNA;Artificial Sequence> ugaauuuguauaug
<SEQ ID NO. 653;RNA;Artificial Sequence> gaauccuaguag
741-3779

CA 02677068 2009-09-01
<SEQ ID NO. 654;RNA; Artificial Sequence> gaaagggaag
<SEQ ID NO. 655;RNA;Artificial Sequence> uaucggcaugc
<SEQ ID NO. 656;RNA;Artificial Sequence> caccucauagua
<SEQ ID NO. 657;RNA;Artificial Sequence> ccagaauugcc
<SEQ ID NO. 658;RNA;Artificial Sequence> uggugaucugg
<SEQ ID NO. 659;RNA;Artificial Sequence> gaucuggguaau
<SEQ ID NO. 660;RNA;Artificial Sequence> ggaugugaugaa
<SEQ ID NO. 661;RNA;Artificial Sequence> cauuuccacagc
<SEQ ID NO. 662;RNA;Artificial Sequence> acagcuacacc
<SEQ ID NO. 663;RNA;Artificial Sequence> ugcaguucuuac
<SEQ ID NO. 664;RNA;Artificial Sequence> acgagaagaaga
<SEQ ID NO. 665;RNA;Artificial Sequence> cgagaagaagau
<SEQ ID NO. 666;RNA;Artificial Sequence> aagaagaucauuuac
<SEQ ID NO. 667;RNA;Artificial Sequence> agaggaagagg
<SEQ ID NO. 668;RNA;Artificial Sequence> gaggaagaggug
<SEQ ID NO. 669;RNA;Artificial Sequence> cuacuuugagggc
<SEQ ID NO. 670;RNA;Artificial Sequence> agggcaucuccu
<SEQ ID NO. 671;RNA;Artificial Sequence> ggagugauau
<SEQ ID NO. 672;RNA;Artificial Sequence> gagugauaugg
<SEQ ID NO. 673;RNA;Artificial Sequence> ugcaguaaagau
<SEQ ID NO. 674;RNA;Artificial Sequence> aguaaagauccua
<SEQ ID NO. 675;RNA;Artificial Sequence> ugacaaaggaca
<SEQ ID NO. 676;RNA;Artificial Sequence> gcaauugugaccc
<SEQ ID NO. 677;RNA;Artificial Sequence> aacaucauccau
<SEQ ID NO. 678;RNA;Artificial Sequence> ugaaauccaaca
<SEQ ID NO. 679;RNA;Artificial Sequence> aacaauauauuucuc
<SEQ ID NO. 680;RNA;Artificial Sequence> aacaguaaagucac
<SEQ ID NO. 681;RNA;Artificial Sequence> ugugaagaaaguaa
<SEQ ID NO. 682;RNA;Artificial Sequence> cuuccgagccauc
<SEQ ID NO. 683;RNA;Artificial Sequence> aauggagguuga
<SEQ ID NO. 684;RNA;Artificial Sequence> ggagguugaaua
<SEQ ID NO. 685;RNA;Artificial Sequence> auuuugaguuuuc
<SEQ ID NO. 686;RNA;Artificial Sequence> uauccuguuugu
<SEQ ID NO. 687;RNA;Artificial Sequence> ccuguuuguuc
<SEQ ID NO. 688;RNA;Artificial Sequence> cucuacagcc
<SEQ ID NO. 689;RNA;Artificial Sequence> ucuuccauagcu
<SEQ ID NO. 690;RNA;Artificial Sequence> auaaucuuccug
<SEQ ID NO.691;RNA;Artificial Sequence> uaaucuuccugu
<SEQ ID NO. 692;RNA;Artificial Sequence> cuucaugacuug
<SEQ ID NO. 693;RNA;Artificial Sequence> aagagggagaga
<SEQ ID NO. 694;RNA;Artificial Sequence> cgucuccuacca
<SEQ ID NO. 695;RNA;Artificial Sequence> gaucaaucggcc
<SEQ ID NO. 696;RNA;Artificial Sequence> ggacgaacaucc
<SEQ ID NO. 697;RNA;Artificial Sequence> agggucggaac
<SEQ ID NO. 698;RNA;Artificial Sequence> ucggaaccca
<SEQ ID NO. 699;RNA;Artificial Sequence> acccaagcuua
<SEQ ID NO. 700;RNA;Artificial Sequence> gaacuuuaagcaac
<SEQ ID NO. 701;RNA;Artificial Sequence> acuauucagug
<SEQ ID NO. 702;RNA;Artificial Sequence> cuauucagugg
<SEQ ID NO. 703;RNA;Artificial Sequence> aaacacagauaac
<SEQ ID NO. 704;RNA;Artificial Sequence> cuuaagaaaaga
<SEQ ID NO. 705;RNA;Artificial Sequence> cugaaggagugu
<SEQ ID NO. 706;RNA;Artificial Sequence> ucaccgcggg
<SEQ ID NO. 707;RNA;Artificial Sequence> agcagaaauaagcg
<SEQ ID NO. 708;RNA;Artificial Sequence> aagcgugccguu
<SEQ ID NO. 709;RNA;Artificial Sequence> agaaacagucac
<SEQ ID NO. 710;RNA;Artificial Sequence> agaggaagaagg
<SEQ ID NO. 711;RNA;Artificial Sequence> uguauucaaaauau
<SEQ ID NO. 712;RNA;Artificial Sequence> auuuuccucccuu
<SEQ ID NO. 713;RNA;Artificial Sequence> caaagaaagauag
<SEQ ID NO. 714;RNA;Artificial Sequence> aagaaagauaga
<SEQ ID NO. 715;RNA;Artificial Sequence> gaaagcauuuguu
<SEQ ID NO. 716;RNA;Artificial Sequence> ugaguuaaacgaa
<SEQ ID NO. 717;RNA;Artificial Sequence> acugauacagaa
<SEQ ID NO. 718;RNA;Artificial Sequence> auauuauauaua
<SEQ ID NO. 719;RNA;Artificial Sequence> auuauauauaua
<SEQ ID NO. 720;RNA;Artificial Sequence> ucacuggaugua
<SEQ ID NO.721;RNA;Artificial Sequence> cagggaagagga
<SEQ ID NO.722;RNA;Artificial Sequence> augaucuuuuuuuug
<SEQ ID NO. 723;RNA;Artificial Sequence> aguucacggcc
<SEQ ID NO. 724;RNA;Artificial Sequence> caccaucacacca
<SEQ ID NO. 725;RNA;Artificial Sequence> ccugcggguuu
<SEQ ID NO. 726;RNA;Artificial Sequence> auccaguuug
741-3780

CA 02677068 2009-09-01
<SEQ ID NO. 727;RNA;Artificial Sequence> guuaaggacuucu
<SEQ ID NO. 728;RNA; Artificial Sequence> cagugggacagag
<SEQ ID NO. 729;RNA;Artificial Sequence> aauuuguuauugug
<SEQ ID NO. 730;RNA; Artificial Sequence> uucaaaugcauuu
<SEQ ID NO. 731;RNA;Artificial Sequence> caggaaagcc
<SEQ ID NO. 732;RNA;Artificial Sequence> aggaaagcccu
<SEQ ID NO. 733;RNA;Artificial Sequence> cccagcauggcc
<SEQ ID NO. 734;RNA;Artificial Sequence> cuucucccuga
<SEQ ID NO. 735;RNA; Artificial Sequence> gaagaagcccuu
<SEQ ID NO.736;RNA;Artificial Sequence> agaagcccuuca
<SEQ ID NO.737;RNA;Artificial Sequence> gcccuucagcg
<SEQ ID NO. 738;RNA;Artificial Sequence> ccuucagcggc
<SEQ ID NO. 739;RNA;Artificial Sequence> ucagcggccagu
<SEQ ID NO. 740;RNA;Artificial Sequence> ugaaaagcuccg
<SEQ ID NO. 741;RNA;Artificial Sequence> aaaagcuccgg
<SEQ ID NO. 742;RNA;Artificial Sequence> agucaacagucug
<SEQ ID NO. 743;RNA;Artificial Sequence> cagaguucaaaag
<SEQ ID NO. 744;RNA;Artificial Sequence> agaguucaaaagc
<SEQ ID NO. 745;RNA;Artificial Sequence> uucaaaagcccu
<SEQ ID NO. 746;RNA;Artificial Sequence> ucaaaagcccuu
<SEQ ID NO. 747;RNA;Artificial Sequence> aaaagcccuuca
<SEQ ID NO. 748;RNA;Artificial Sequence> aaagcccuucag
<SEQ ID NO. 749;RNA;Artificial Sequence> gugaagccgcucg
<SEQ ID NO. 750;RNA;Artificial Sequence> cacgccagucaa
<SEQ ID NO. 751;RNA;Artificial Sequence> uucuuggugcgug
<SEQ ID NO. 752;RNA; Artificial Sequence> auuggauucaucag
<SEQ ID NO. 753;RNA;Artificial Sequence> uggaauaccuaag
<SEQ ID NO. 754;RNA;Artificial Sequence> auuugaggcuca
<SEQ ID NO. 755;RNA;Artificial Sequence> ucuacaauugg
<SEQ ID NO. 756;RNA;Artificial Sequence> uaguuaggagcc
<SEQ ID NO. 757;RNA;Artificial Sequence> agucaauauccac
<SEQ ID NO. 758;RNA;Artificial Sequence> auguucagucaca
<SEQ ID NO. 759;RNA;Artificial Sequence> acacacacauac
<SEQ ID NO. 760;RNA;Artificial Sequence> uuccuuuugcuu
<SEQ ID NO. 761;RNA;Artificial Sequence> uuuuaaaguaauuuuu
<SEQ ID NO. 762;RNA;Artificial Sequence> caacagucaaugg
<SEQ ID NO. 763;RNA;Artificial Sequence> ucgacaaaccaau
<SEQ ID NO. 764;RNA;Artificial Sequence> acugcuaccacu
<SEQ ID NO. 765;RNA;Artificial Sequence> gcaagcggucuua
<SEQ ID NO. 766;RNA;Artificial Sequence> ggucuuaccggcu
<SEQ ID NO. 767;RNA;Artificial Sequence> gauggguuacc
<SEQ ID NO. 768;RNA;Artificial Sequence> guuaccugcga
<SEQ ID NO. 769;RNA;Artificial Sequence> aaucuugcugag
<SEQ ID NO. 770;RNA;Artificial Sequence> agcauaaaacagu
<SEQ ID NO. 771;RNA;Artificial Sequence> guccuuuauccu
<SEQ ID NO. 772;RNA;Artificial Sequence> caacgcaaguug
<SEQ ID NO.773;RNA;Artificial Sequence> aaacugaaaccau
<SEQ ID NO. 774;RNA;Artificial Sequence> acuuuguuaaauau
<SEQ ID NO. 775;RNA;Artificial Sequence> guauauuaaaaguu
<SEQ ID NO. 776;RNA;Artificial Sequence> guuuugacuuaac
<SEQ ID NO. 777;RNA;Artificial Sequence> gcaaacucagcac
<SEQ ID NO. 778;RNA;Artificial Sequence> ugcugaccuca
<SEQ ID NO. 779;RNA;Artificial Sequence> uuuauucagaucgc
<SEQ ID NO. 780;RNA;Artificial Sequence> aggguucugggau
<SEQ ID NO. 781;RNA;Artificial Sequence> auauuggaaauuaug
<SEQ ID NO. 782;RNA;Artificial Sequence> auggaagcacuag
<SEQ ID NO. 783;RNA;Artificial Sequence> guuuuuaugugga
<SEQ ID NO.784;RNA;Artificial Sequence> ggaauugguaga
<SEQ ID NO. 785;RNA;Artificial Sequence> uuagacuuggaga
<SEQ ID NO. 786;RNA;Artificial Sequence> uuacaguauucca
<SEQ ID NO. 787;RNA;Artificial Sequence> ccacugaugaauuaa
<SEQ ID NO. 788;RNA;Artificial Sequence> ccacaucaucac
<SEQ ID NO. 789;RNA;Artificial Sequence> cucaccaaacaga
<SEQ ID NO. 790;RNA;Artificial Sequence> ggaacaugaugg
<SEQ ID NO. 791;RNA;Artificial Sequence> cauguagacugc
<SEQ ID NO. 792;RNA;Artificial Sequence> ggaucuauuuaug
<SEQ ID NO. 793;RNA;Artificial Sequence> gcacuauuauca
<SEQ ID NO. 794;RNA;Artificial Sequence> aucaguucugc
<SEQ ID NO. 795;RNA;Artificial Sequence> agauuaaaccuac
<SEQ ID NO. 796;RNA;Artificial Sequence> auaaaauccuucu
<SEQ ID NO. 797;RNA;Artificial Sequence> aaugcuguagac
<SEQ ID NO.798;RNA;Artificial Sequence> uugauaggaauag
<SEQ ID NO. 799;RNA;Artificial Sequence> aauggcccuga
741-3781

CA 02677068 2009-09-01
<SEQ ID NO. 800;RNA;Artificial Sequence> uuccucaagca
<SEQ ID NO. 801;RNA;Artificial Sequence> guucagccca
<SEQ ID NO. 802;RNA;Artificial Sequence> gcugcugaacc
<SEQ ID NO. 803;RNA;Artificial Sequence> aaguucucuuca
<SEQ ID NO. 804;RNA;Artificial Sequence> ccagccuagag
<SEQ ID NO. 805;RNA;Artificial Sequence> cucugugaagugu
<SEQ ID NO. 806;RNA;Artificial Sequence> ugagaaaauuucaa
<SEQ ID NO. 807;RNA;Artificial Sequence> aauccuccuga
<SEQ ID NO. 808;RNA;Artificial Sequence> gugacaucauau
<SEQ ID NO. 809;RNA;Artificial Sequence> aaucuucaucaua
<SEQ ID NO. 810;RNA;Artificial Sequence> gacuagcuauuaa
<SEQ ID NO. 811;RNA;Artificial Sequence> ucucuacuaaaaau
<SEQ ID NO. 812;RNA;Artificial Sequence> ucuaucucgccu
<SEQ ID NO. 813;RNA;Artificial Sequence> cuucgguccaguu
<SEQ ID NO. 814;RNA;Artificial Sequence> gauguagccgc
<SEQ ID NO. 815;RNA;Artificial Sequence> ugaggagacuug
<SEQ ID NO. 816;RNA;Artificial Sequence> gaguagugagga
<SEQ ID NO. 817;RNA;Artificial Sequence> cagaugaguacaaa
<SEQ ID NO. 818;RNA;Artificial Sequence> guuguuaaugggc
<SEQ ID NO. 819;RNA;Artificial Sequence> uuuuuaauuuauu
<SEQ ID NO. 820;RNA;Artificial Sequence> uauuuaaauaug
<SEQ ID NO. 821;RNA;Artificial Sequence> uauccuuuguuuc
<SEQ ID NO. 822;RNA;Artificial Sequence> cgucuaaguguuug
<SEQ ID NO. 823;RNA;Artificial Sequence> accugugacaaa
<SEQ ID NO. 824;RNA;Artificial Sequence> ccaggcugaauua
<SEQ ID NO. 825;RNA;Artificial Sequence> gucauucuuacaau
<SEQ ID NO. 826;RNA;Artificial Sequence> ucauucuuacaauug
<SEQ ID NO. 827;RNA;Artificial Sequence> cagagaguguac
<SEQ ID NO. 828;RNA;Artificial Sequence> agaacucagcag
<SEQ ID NO. 829;RNA;Artificial Sequence> uuuauuuucagua
<SEQ ID NO. 830;RNA;Artificial Sequence> ucuuaaauggaa
<SEQ ID NO. 831;RNA;Artificial Sequence> ugccuaaaauugu
<SEQ ID NO. 832;RNA;Artificial Sequence> agacugugagcu
<SEQ ID NO. 833;RNA;Artificial Sequence> ugcuuuuuauuaau
<SEQ ID NO. 834;RNA;Artificial Sequence> cucuucuuacauu
<SEQ ID NO. 835;RNA;Artificial Sequence> cauuuguaaaaaugu
<SEQ ID NO. 836;RNA;Artificial Sequence> aucuuaauucauauu
<SEQ ID NO. 837;RNA;Artificial Sequence> gaacuaaucauga
<SEQ ID NO. 838;RNA;Artificial Sequence> ucugcucuuggg
<SEQ ID NO. 839;RNA;Artificial Sequence> caguagcuuugag
<SEQ ID NO. 840;RNA;Artificial Sequence> cacguaauauuuca
<SEQ ID NO. 841;RNA;Artificial Sequence> uauucucuucacu
<SEQ ID NO. 842;RNA;Artificial Sequence> cuaaugcuaagaaa
<SEQ ID NO. 843;RNA;Artificial Sequence> gcugaaaaucaa
<SEQ ID NO. 844;RNA;Artificial Sequence> aauaugauuacuuu
<SEQ ID NO. 845;RNA;Artificial Sequence> cauuuuguucuaca
<SEQ ID NO. 846;RNA;Artificial Sequence> cccgggacucuc
<SEQ ID NO. 847;RNA;Artificial Sequence> ccuuuaaaguaaag
<SEQ ID NO. 848;RNA;Artificial Sequence> ucuggaagccugg
<SEQ ID NO. 849;RNA;Artificial Sequence> aaaacaaaagagag
<SEQ ID NO. 850;RNA;Artificial Sequence> aucaguuaugccg
<SEQ ID NO. 851;RNA;Artificial Sequence> uaaaagaagucca
<SEQ ID NO. 852;RNA;Artificial Sequence> aggugagguua
<SEQ ID NO. 853;RNA;Artificial Sequence> gggaagaggac
<SEQ ID NO. 854;RNA;Artificial Sequence> aagcaaguauugu
<SEQ ID NO. 855;RNA;Artificial Sequence> auuguagcacuc
<SEQ ID NO. 856;RNA;Artificial Sequence> acaaaaccacaaau
<SEQ ID NO. 857;RNA;Artificial Sequence> uaagcccauaca
<SEQ ID NO. 858;RNA;Artificial Sequence> agcccauacag
<SEQ ID NO. 859;RNA;Artificial Sequence> cagaaaccuucc
<SEQ ID NO. 860;RNA;Artificial Sequence> guauaccuac
<SEQ ID NO. 861;RNA;Artificial Sequence> gccaguuuucgga
<SEQ ID NO. 862;RNA;Artificial Sequence> ggaacaggg
<SEQ ID NO. 863;RNA;Artificial Sequence> uuaacuuuccagu
<SEQ ID NO. 864;RNA;Artificial Sequence> aaaguuugguuuug
<SEQ ID NO. 865;RNA;Artificial Sequence> cuucccacugua
<SEQ ID NO. 866;RNA;Artificial Sequence> ugauaccauauga
<SEQ ID NO. 867;RNA;Artificial Sequence> aacaugggcug
<SEQ ID NO. 868;RNA;Artificial Sequence> caacuuuuucaua
<SEQ ID NO. 869;RNA;Artificial Sequence> caugaggccgga
<SEQ ID NO. 870;RNA;Artificial Sequence> acugcauuugu
<SEQ ID NO. 871;RNA;Artificial Sequence> aauguuuacuacc
<SEQ ID NO. 872;RNA;Artificial Sequence> aauuuuuugaugaaa
741-3782

CA 02677068 2009-09-01
<SEQ ID NO. 873;RNA;Artificial Sequence> cagugugugaauuu
<SEQ ID NO. 874;RNA;Artificial Sequence> gagcaauguaugu
<SEQ ID NO. 875;RNA;Artificial Sequence> aaagcacauauaua
<SEQ ID NO. 876;RNA;Artificial Sequence> guaauaguuucucc
<SEQ ID NO. 877;RNA;Artificial Sequence> aguuucuccaaau
<SEQ ID NO. 878;RNA;Artificial Sequence> uacuuccuagaaa
<SEQ ID NO. 879;RNA;Artificial Sequence> uacaccauauaug
<SEQ ID NO. 880;RNA;Artificial Sequence> auauaugaauggag
<SEQ ID NO. 881;RNA;Artificial Sequence> acgagaagaagau
<SEQ ID NO. 882;RNA;Artificial Sequence> ucauuuacaggga
<SEQ ID NO. 883;RNA;Artificial Sequence> cauuuacagggac
<SEQ ID NO. 884;RNA;Artificial Sequence> agggaccuga
<SEQ ID NO. 885;RNA;Artificial Sequence> uguuugacugcauc
<SEQ ID NO. 886;RNA;Artificial Sequence> uuugacugcaucg
<SEQ ID NO. 887;RNA;Artificial Sequence> gaguucacaggg
<SEQ ID NO. 888;RNA;Artificial Sequence> ggcaccucugucc
<SEQ ID NO. 889;RNA;Artificial Sequence> gguuugucuuuuuaa
<SEQ ID NO. 890;RNA;Artificial Sequence> uuugucuuuuuaag
<SEQ ID NO. 891;RNA;Artificial Sequence> ccuaaagguuguc
<SEQ ID NO. 892;RNA;Artificial Sequence> aagguugucgac
<SEQ ID NO. 893;RNA;Artificial Sequence> accuggcaauugu
<SEQ ID NO. 894;RNA;Artificial Sequence> aguggugcgagg
<SEQ ID NO. 895;RNA;Artificial Sequence> agagacaugaaau
<SEQ ID NO. 896;RNA;Artificial Sequence> auauauuucucca
<SEQ ID NO. 897;RNA;Artificial Sequence> caugaaggcu
<SEQ ID NO. 898;RNA;Artificial Sequence> gcuggaguggu
<SEQ ID NO. 899;RNA;Artificial Sequence> aggaagagagg
<SEQ ID NO. 900;RNA;Artificial Sequence> cuugcaucgggc
<SEQ ID NO. 901;RNA;Artificial Sequence> auauccuacugug
<SEQ ID NO. 902;RNA;Artificial Sequence> uccuacuguguaa
<SEQ ID NO. 903;RNA;Artificial Sequence> ccuuguagugua
<SEQ ID NO. 904;RNA;Artificial Sequence> ucuuuguugauug
<SEQ ID NO. 905;RNA;Artificial Sequence> uuuguugauugaaa
<SEQ ID NO.906;RNA;Artificial Sequence> uucuuuuucuuccau
<SEQ ID NO. 907;RNA;Artificial Sequence> aaucuuccuucua
<SEQ ID NO. 908;RNA;Artificial Sequence> uugaaugcuucau
<SEQ ID NO. 909;RNA;Artificial Sequence> ugaaugcuucaug
<SEQ ID NO. 910;RNA;Artificial Sequence> aauucuacuuuga
<SEQ ID NO.911;RNA;Artificial Sequence> agcaacuacagac
<SEQ ID NO.912;RNA;Artificial Sequence> gaccaaggucaac
<SEQ ID NO. 913;RNA;Artificial Sequence> cgacuaucucgac
<SEQ ID NO. 914;RNA;Artificial Sequence> aaccuucccaaac
<SEQ ID NO. 915;RNA;Artificial Sequence> ccaagcuuagaacu
<SEQ ID NO.916;RNA;Artificial Sequence> agcuuagaacuuuaa
<SEQ ID NO. 917;RNA;Artificial Sequence> aagaccaccac
<SEQ ID NO.918;RNA;Artificial Sequence> gcgagaaauaaagu
<SEQ ID NO. 919;RNA;Artificial Sequence> cgagaaauaaaguu
<SEQ ID NO. 920;RNA;Artificial Sequence> aggaaaugaucc
<SEQ ID NO. 921;RNA;Artificial Sequence> gaagaaaugaaac
<SEQ ID NO. 922;RNA;Artificial Sequence> guuuccauccucc
<SEQ ID NO. 923;RNA;Artificial Sequence> acugaaaaucuuuga
<SEQ ID NO. 924;RNA;Artificial Sequence> ugccguucagg
<SEQ ID NO. 925;RNA;Artificial Sequence> caggguccagaag
<SEQ ID NO. 926;RNA;Artificial Sequence> ucaagacugcuug
<SEQ ID NO. 927;RNA;Artificial Sequence> uccaugucuuugg
<SEQ ID NO. 928;RNA;Artificial Sequence> gccugaaacac
<SEQ ID NO. 929;RNA;Artificial Sequence> ucucuguaccuc
<SEQ ID NO. 930;RNA;Artificial Sequence> agcaagacaaga
<SEQ ID NO. 931;RNA;Artificial Sequence> gcaagacaagaaa
<SEQ ID NO. 932;RNA;Artificial Sequence> uguacaagaucc
<SEQ ID NO. 933;RNA;Artificial Sequence> cguacuugcaga
<SEQ ID NO. 934;RNA;Artificial Sequence> cgaucgauacaga
<SEQ ID NO. 935;RNA;Artificial Sequence> uauaaaaauaaau
<SEQ ID NO. 936;RNA;Artificial Sequence> uaaaaauaaauau
<SEQ ID NO.937;RNA;Artificial Sequence> uuugacugcugug
<SEQ ID NO.938;RNA;Artificial Sequence> ggagaugagagac
<SEQ ID NO. 939;RNA;Artificial Sequence> ucccacuugg
<SEQ ID NO. 940;RNA;Artificial Sequence> guucacggcc
<SEQ ID NO. 941;RNA;Artificial Sequence> accaucacacca
<SEQ ID NO.942;RNA;Artificial Sequence> cugcggguuu
<SEQ ID NO. 943;RNA;Artificial Sequence> uccaguuug
<SEQ ID NO. 944;RNA;Artificial Sequence> uuaaggacuucu
<SEQ ID NO. 945;RNA;Artificial Sequence> agugggacagag
741-3783

CA 02677068 2009-09-01
<SEQ ID NO. 946;RNA;Artificial Sequence> auuuguuauugug
<SEQ ID NO. 947;RNA;Artificial Sequence> ucaaaugcauuu
<SEQ ID NO. 948;RNA;Artificial Sequence> aggaaagcc
<SEQ ID NO. 949;RNA;Artificial Sequence> ggaaagcccu
<SEQ ID NO. 950;RNA;Artificial Sequence> ccagcauggcc
<SEQ ID NO. 95 1;RNA;Artificial Sequence> uucucccuga
<SEQ ID NO.952;RNA;Artificial Sequence> aagaagcccuu
<SEQ ID NO. 953;RNA;Artificial Sequence> gaagcccuuca
<SEQ ID NO. 954;RNA;Artificial Sequence> cccuucagcg
<SEQ ID NO. 955;RNA;Artificial Sequence> cuucagcggc
<SEQ ID NO.956;RNA;Artificial Sequence> cagcggccagu
<SEQ ID NO. 957;RNA;Artificial Sequence> gaaaagcuccg
<SEQ ID NO. 958;RNA;Artificial Sequence> aaagcuccgg
<SEQ ID NO. 959;RNA;Artificial Sequence> gucaacagucug
<SEQ ID NO. 960;RNA;Artificial Sequence> agaguucaaaag
<SEQ ID NO. 961;RNA;Artificial Sequence> gaguucaaaagc
<SEQ ID NO. 962;RNA;Artificial Sequence> ucaaaagcccu
<SEQ ID NO. 963;RNA;Artificial Sequence> caaaagcccuu
<SEQ ID NO.964;RNA;Artificial Sequence> aaagcccuuca
<SEQ ID NO. 965;RNA;Artificial Sequence> aagcccuucag
<SEQ ID NO. 966;RNA;Artificial Sequence> ugaagccgcucg
<SEQ ID NO. 967;RNA;Artificial Sequence> acgccagucaa
<SEQ ID NO. 968;RNA;Artificial Sequence> ucuuggugcgug
<SEQ ID NO. 969;RNA;Artificial Sequence> uuggauucaucag
<SEQ ID NO. 970;RNA;Artificial Sequence> ggaauaccuaag
<SEQ ID NO. 971;RNA;Artificial Sequence> uuugaggcuca
<SEQ ID NO. 972;RNA;Artificial Sequence> cuacaauugg
<SEQ ID NO.973;RNA;Artificial Sequence> aguuaggagcc
<SEQ ID NO. 974;RNA;Artificial Sequence> gucaauauccac
<SEQ ID NO. 975;RNA;Artificial Sequence> uguucagucaca
<SEQ ID NO. 976;RNA;Artificial Sequence> cacacacauac
<SEQ ID NO. 977;RNA;Artificial Sequence> uccuuuugcuu
<SEQ ID NO. 978;RNA;Artificial Sequence> uuuaaaguaauuuuu
<SEQ ID NO. 979;RNA;Artificial Sequence> aacagucaaugg
<SEQ ID NO. 980;RNA;Artificial Sequence> cgacaaaccaau
<SEQ ID NO.981;RNA;Artificial Sequence> cugcuaccacu
<SEQ ID NO. 982;RNA;Artificial Sequence> caagcggucuua
<SEQ ID NO. 983;RNA;Artificial Sequence> gucuuaccggcu
<SEQ ID NO. 984;RNA;Artificial Sequence> auggguuacc
<SEQ ID NO. 985;RNA;Artificial Sequence> uuaccugcga
<SEQ ID NO. 986;RNA;Artificial Sequence> aucuugcugag
<SEQ ID NO. 987;RNA;Artificial Sequence> gcauaaaacagu
<SEQ ID NO.988;RNA;Artificial Sequence> uccuuuauccu
<SEQ ID NO. 989;RNA;Artificial Sequence> aacgcaaguug
<SEQ ID NO. 990;RNA;Artificial Sequence> aacugaaaccau
<SEQ ID NO.991;RNA;Artificial Sequence> cuuuguuaaauau
<SEQ ID NO. 992;RNA;Artificial Sequence> uauauuaaaaguu
<SEQ ID NO. 993;RNA;Artificial Sequence> uuuugacuuaac
<SEQ ID NO. 994;RNA;Artificial Sequence> caaacucagcac
<SEQ ID NO. 995;RNA;Artificial Sequence> gcugaccuca
<SEQ ID NO. 996;RNA;Artificial Sequence> uuauucagaucgc
<SEQ ID NO. 997;RNA;Artificial Sequence> ggguucugggau
<SEQ ID NO. 998;RNA;Artificial Sequence> uauuggaaauuaug
<SEQ ID NO. 999;RNA;Artificial Sequence> uggaagcacuag
<SEQ ID NO. 1000;RNA;Artificial Sequence> uuuuuaugugga
<SEQ ID NO. 1001;RNA;Artificial Sequence> gaauugguaga
<SEQ ID NO. 1002;RNA;Artificial Sequence> uagacuuggaga
<SEQ ID NO. 1003;RNA;Artificial Sequence> uacaguauucca
<SEQ ID NO. 1004;RNA;Artificial Sequence> cacugaugaauuaa
<SEQ ID NO. 1005;RNA;Artificial Sequence> cacaucaucac
<SEQ ID NO. 1006;RNA;Artificial Sequence> ucaccaaacaga
<SEQ ID NO. 1007;RNA;Artificial Sequence> gaacaugaugg
<SEQ ID NO. 1008;RNA;Artificial Sequence> auguagacugc
<SEQ ID NO. 1009;RNA;Artificial Sequence> gaucuauuuaug
<SEQ ID NO. 1010;RNA;Artificial Sequence> cacuauuauca
<SEQ ID NO. 1011;RNA;Artificial Sequence> ucaguucugc
<SEQ ID NO. 1012;RNA;Artificial Sequence> gauuaaaccuac
<SEQ ID NO. 1013;RNA;Artificial Sequence> uaaaauccuucu
<SEQ ID NO. 1014;RNA;Artificial Sequence> augcuguagac
<SEQ ID NO. 1015;RNA;Artificial Sequence> ugauaggaauag
<SEQ ID NO. 1016;RNA;Artificial Sequence> auggcccuga
<SEQ ID NO. 1017;RNA;Artificial Sequence> uccucaagca
<SEQ ID NO. 1018;RNA;Artificial Sequence> uucagccca
741-3784

CA 02677068 2009-09-01
<SEQ ID NO. 1019;RNA;Artificial Sequence> cugcugaacc
<SEQ ID NO. 1020;RNA;Artificial Sequence> aguucucuuca
<SEQ ID NO. 1021;RNA;Artificial Sequence> cagccuagag
<SEQ ID NO. 1022;RNA;Artificial Sequence> ucugugaagugu
<SEQ ID NO. 1023;RNA;Artificial Sequence> gagaaaauuucaa
<SEQ ID NO. 1024;RNA;Artificial Sequence> auccuccuga
<SEQ ID NO. 1025;RNA;Artificial Sequence> ugacaucauau
<SEQ ID NO. 1026;RNA;Artificial Sequence> aucuucaucaua
<SEQ ID NO. 1027;RNA;Artificial Sequence> acuagcuauuaa
<SEQ ID NO. 1028;RNA;Artificial Sequence> cucuacuaaaaau
<SEQ ID NO. 1029;RNA;Artificial Sequence> cuaucucgccu
<SEQ ID NO. 1030;RNA;Artificial Sequence> uucgguccaguu
<SEQ ID NO. 1031;RNA;Artificial Sequence> auguagccgc
<SEQ ID NO. 1032;RNA;Artificial Sequence> gaggagacuug
<SEQ ID NO. 1033;RNA;Artificial Sequence> aguagugagga
<SEQ ID NO. 1034;RNA;Artificial Sequence> agaugaguacaaa
<SEQ ID NO. 1035;RNA;Artificial Sequence> uuguuaaugggc
<SEQ ID NO. 1036;RNA;Artificial Sequence> uuuuaauuuauu
<SEQ ID NO. 1037;RNA;Artificial Sequence> auuuaaauaug
<SEQ ID NO. 1038;RNA;Artificial Sequence> auccuuuguuuc
<SEQ ID NO. 1039;RNA;Artificial Sequence> gucuaaguguuug
<SEQ ID NO. 1040;RNA;Artificial Sequence> ccugugacaaa
<SEQ ID NO. 1041;RNA;Artificial Sequence> caggcugaauua
<SEQ ID NO. 1042;RNA;Artificial Sequence> ucauucuuacaau
<SEQ ID NO. 1043;RNA;Artificial Sequence> cauucuuacaauug
<SEQ ID NO. 1044;RNA;Artificial Sequence> agagaguguac
<SEQ ID NO. 1045;RNA;Artificial Sequence> gaacucagcag
<SEQ ID NO. 1046;RNA;Artificial Sequence> uuauuuucagua
<SEQ ID NO. 1047;RNA;Artificial Sequence> cuuaaauggaa
<SEQ ID NO. 1048;RNA;Artificial Sequence> gccuaaaauugu
<SEQ ID NO. 1049;RNA;Artificial Sequence> acuaacaucugg
<SEQ ID NO. 1050;RNA;Artificial Sequence> gacugugagcu
<SEQ ID NO. 1051;RNA;Artificial Sequence> gcuuuuuauuaau
<SEQ ID NO. 1052;RNA;Artificial Sequence> ucuucuuacauu
<SEQ ID NO. 1053;RNA;Artificial Sequence> auuuguaaaaaugu
<SEQ ID NO. I054;RNA;Artificial Sequence> ucuuaauucauauu
<SEQ ID NO. 1055;RNA;Artificial Sequence> aacuaaucauga
<SEQ ID NO. 1056;RNA;Artificial Sequence> cugcucuuggg
<SEQ ID NO. 1057;RNA;Artificial Sequence> aguagcuuugag
<SEQ ID NO. 1058;RNA;Artificial Sequence> acguaauauuuca
<SEQ ID NO. 1059;RNA;Artificial Sequence> auucucuucacu
<SEQ ID NO. 1060;RNA;Artificial Sequence> uaaugcuaagaaa
<SEQ ID NO. 1061;RNA;Artificial Sequence> cugaaaaucaa
<SEQ ID NO. 1062;RNA;Artificial Sequence> auaugauuacuuu
<SEQ ID NO. 1063;RNA;Artificial Sequence> auuuuguucuaca
<SEQ ID NO. I064;RNA;Artificial Sequence> ccgggacucuc
<SEQ ID NO. 1065;RNA;Artificial Sequence> cuuuaaaguaaag
<SEQ ID NO. 1066;RNA;Artificial Sequence> cuggaagccugg
<SEQ ID NO. 1067;RNA;Artificial Sequence> aaacaaaagagag
<SEQ ID NO. 1068;RNA;Artificial Sequence> ucaguuaugccg
<SEQ ID NO. 1069;RNA;Artificial Sequence> aaaagaagucca
<SEQ ID NO. 1070;RNA;Artificial Sequence> ggugagguua
<SEQ ID NO. 1071;RNA;Artificial Sequence> ggaagaggac
<SEQ ID NO. 1072;RNA;Artificial Sequence> agcaaguauugu
<SEQ ID NO. 1073;RNA;Artificial Sequence> uuguagcacuc
<SEQ ID NO. 1074;RNA;Artificial Sequence> caaaaccacaaau
<SEQ ID NO. 1075;RNA;Artificial Sequence> aagcccauaca
<SEQ ID NO. 1076;RNA;Artificial Sequence> gcccauacag
<SEQ ID NO. 1077;RNA;Artificial Sequence> agaaaccuucc
<SEQ ID NO. 1078;RNA;Attificial Sequence> uauaccuac
<SEQ ID NO. 1079;RNA;Artificial Sequence> ccaguuuucgga
<SEQ ID NO. 1080;RNA;Artificial Sequence> gaacaggg
<SEQ ID NO. 1081;RNA;Artificial Sequence> uaacuuuccagu
<SEQ ID NO. 1082;RNA;Artificial Sequence> aaguuugguuuug
<SEQ ID NO. 1083;RNA;Artificial Sequence> uucccacugua
<SEQ ID NO. 1084;RNA;Artificial Sequence> gauaccauauga
<SEQ ID NO. 1085;RNA;Artificial Sequence> acaugggcug
<SEQ ID NO. I086;RNA;Artificial Sequence> aacuuuuucaua
<SEQ ID NO. 1087;RNA;Artificial Sequence> augaggccgga
<SEQ ID NO. 1088;RNA;Artificial Sequence> cugcauuugu
<SEQ ID NO. 1089;RNA;Artificial Sequence> auguuuacuacc
<SEQ ID NO. 1090;RNA;Artificial Sequence> auuuuuugaugaaa
<SEQ ID NO. 1091;RNA;Artificial Sequence> agugugugaauuu
741-3785

CA 02677068 2009-09-01
<SEQ ID NO. 1092;RNA;Artificial Sequence> agcaauguaugu
<SEQ ID NO. 1093;RNA;Artificial Sequence> aagcacauauaua
<SEQ ID NO. 1094;RNA;Artificial Sequence> uaauaguuucucc
<SEQ ID NO. 1095;RNA;Artificial Sequence> guuucuccaaau
<SEQ ID NO. 1096;RNA;Artificial Sequence> acuuccuagaaa
<SEQ ID NO. 1097;RNA;Artificial Sequence> acaccauauaug
<SEQ ID NO. 1098;RNA;Artificial Sequence> uauaugaauggag
<SEQ ID NO. 1099;RNA;Artificial Sequence> cauuuacaggga
<SEQ ID NO. I 100;RNA;Artificial Sequence> auuuacagggac
<SEQ ID NO. 1101;RNA;Artificial Sequence> gggaccuga
<SEQ ID NO. 1102;RNA;Artificial Sequence> guuugacugcauc
<SEQ ID NO. 1103;RNA;Artificial Sequence> uugacugcaucg
<SEQ ID NO. 1104;RNA;Artificial Sequence> aguucacaggg
<SEQ ID NO. 1105;RNA;Artificial Sequence> gcaccucugucc
<SEQ ID NO. 1106;RNA;Artificial Sequence> guuugucuuuuuaa
<SEQ ID NO. 1107;RNA;Artificial Sequence> uugucuuuuuaag
<SEQ ID NO. 1108;RNA;Artificial Sequence> cuaaagguuguc
<SEQ ID NO. 1109;RNA;Artificial Sequence> agguugucgac
<SEQ ID NO. 1 110;RNA;Artificial Sequence> ccuggcaauugu
<SEQ ID NO. 1111;RNA;Artificial Sequence> guggugcgagg
<SEQ ID NO. 1112;RNA;Artificial Sequence> gagacaugaaau
<SEQ ID NO. 11 13;RNA;Artificial Sequence> uauauuucucca
<SEQ ID NO. 11 14;RNA;Artificial Sequence> augaaggcu
<SEQ ID NO. 11 15;RNA;Artificial Sequence> cuggaguggu
<SEQ ID NO. 1116;RNA;Artificial Sequence> ggaagagagg
<SEQ ID NO. 11 17;RNA;Artificial Sequence> uugcaucgggc
<SEQ ID NO. 11 18;RNA;Artificial Sequence> uauccuacugug
<SEQ ID NO. 1119;RNA;Artificial Sequence> ccuacuguguaa
<SEQ ID NO. 1120;RNA;Artificial Sequence> cuuguagugua
<SEQ ID NO. 1121;RNA;Artificial Sequence> cuuuguugauug
<SEQ ID NO. 1122;RNA;Artificial Sequence> uuguugauugaaa
<SEQ ID NO. 1123;RNA;Artificial Sequence> ucuuuuucuuccau
<SEQ ID NO. 1124;RNA;Artificial Sequence> aucuuccuucua
<SEQ ID NO. 1125;RNA;Artificial Sequence> ugaaugcuucau
<SEQ ID NO. 1126;RNA;Artificial Sequence> gaaugcuucaug
<SEQ ID NO. 1127;RNA;Artificial Sequence> auucuacuuuga
<SEQ ID NO. 1 I28;RNA;Artificial Sequence> gcaacuacagac
<SEQ ID NO. 1129;RNA;Artificial Sequence> accaaggucaac
<SEQ ID NO. 1130;RNA;Artificial Sequence> gacuaucucgac
<SEQ ID NO. 1131;RNA;Artificial Sequence> accuucccaaac
<SEQ ID NO. 1132;RNA;Artificial Sequence> caagcuuagaacu
<SEQ ID NO. 1133;RNA;Artificial Sequence> gcuuagaacuuuaa
<SEQ ID NO. 1134;RNA;Artificial Sequence> aacuuuaagcaac
<SEQ ID NO. 1135;RNA;Artificial Sequence> agaccaccac
<SEQ ID NO. 1136;RNA;Artificial Sequence> cgagaaauaaagu
<SEQ ID NO. 1137;RNA;Artificial Sequence> gagaaauaaaguu
<SEQ ID NO. 1138;RNA;Artificial Sequence> ggaaaugaucc
<SEQ ID NO. 1139;RNA;Artificial Sequence> aagaaaugaaac
<SEQ ID NO. 1140;RNA;Artificial Sequence> uuuccauccucc
<SEQ ID NO. 1141;RNA;Artificial Sequence> cugaaaaucuuuga
<SEQ ID NO. 1142;RNA;Artificial Sequence> gccguucagg
<SEQ ID NO. 1143;RNA;Artificial Sequence> aggguccagaag
<SEQ ID NO. 1144;RNA;Artificial Sequence> caagacugcuug
<SEQ ID NO. 1145;RNA;Artificial Sequence> ccaugucuuugg
<SEQ ID NO. 1146;RNA;Artificial Sequence> ccugaaacac
<SEQ ID NO. 1147;RNA;Artificial Sequence> cucuguaccuc
<SEQ ID NO. 1148;RNA;Artificial Sequence> gcaagacaaga
<SEQ ID NO. 1149;RNA;Artificial Sequence> caagacaagaaa
<SEQ ID NO. 1150;RNA;Artificial Sequence> guacaagaucc
<SEQ ID NO. 1151;RNA;Artificial Sequence> guacuugcaga
<SEQ ID NO. 1152;RNA;Artificial Sequence> gaucgauacaga
<SEQ ID NO. 1153;RNA;Artificial Sequence> auaaaaauaaau
<SEQ ID NO. 1154;RNA;Artificial Sequence> aaaaauaaauau
<SEQ ID NO. 1155;RNA;Artificial Sequence> uugacugcugug
<SEQ ID NO. 1156;RNA;Artificial Sequence> gagaugagagac
<SEQ ID NO. 1157;RNA;Artificial Sequence> cccacuugg
<SEQ ID NO. 1158;RNA;Homo sapiens>
CUGGCGCGCGCGGCCCUGCGGGUGACAGGCAGGCGGGAAGGGGCGGGGCCUCGGGCGGGGCCGCCGUGGGG
AGGAGGGCGGUGGGAGGGGAGGAGUGGAGAUGGCGGCGGCGGCGGCUCAGGGGGGCGGGGGCGGGGAGCCCCGUAG
AACCGAGGGGGUCGGCCCGGGGGUCCCGGGGGAGGUGGAGAUGGUGAAGGGGCAGCCGUUCGACGUGGGCCCGCGCU
ACACGCAGUUGCAGUACAUCGGCGAGGGCGCGUACGGCAUGGUCAGCUCGGCCUAUGACCACGUGCGCAAGACUCGC
GUGGCCAUCAAGAAGAUCAGCCCCUUCGAACAUCAGACCUACUGCCAGCGCACGCUCCGGGAGAUCCAGAUCCUGCU
GCGCUUCCGCCAUGAGAAUGUCAUCGGCAUCCGAGACAUUCUGCGGGCGUCCACCCUGGAAGCCAUGAGAGAUGUCU
741-3786

CA 02677068 2009-09-01
ACAUUGUGCAGGACCUGAUGGAGACUGACCUGUACAAGUUGCUGAAAAGCCAGCAGCUGAGCAAUGACCAUAUCUGC
UACUUCCUCUACCAGAUCCUGCGGGGCCUCAAGUACAUCCACUCCGCCAACGUGCUCCACCGAGAUCUAAAGCCCUCC
AACCUGCUCAUCAACACCACCUGCGACCUUAAGAUUUGUGAUUUCGGCCUGGCCCGGAUUGCCGAUCCUGAGCAUGA
CCACACCGGCUUCCUGACGGAGUAUGUGGCUACGCGCUGGUACCGGGCCCCAGAGAUCAUGCUGAACUCCAAGGGCU
AUACCAAGUCCAUCGACAUCUGGUCUGUGGGCUGCAUUCUGGCUGAGAUGCUCUCUAACCGGCCCAUCUUCCCUGGC
AAGCACUACCUGGAUCAGCUCAACCACAUUCUGGGCAUCCUGGGCUCCCCAUCCCAGGAGGACCUGAAUUGUAUCAU
CAACAUGAAGGCCCGAAACUACCUACAGUCUCUGCCCUCCAAGACCAAGGUGGCUUGGGCCAAGCUUUUCCCCAAGU
CAGACUCCAAAGCCCUUGACCUGCUGGACCGGAUGUUAACCUUUAACCCCAAUAAACGGAUCACAGUGGAGGAAGCG
CUGGCUCACCCCUACCUGGAGCAGUACUAUGACCCGACGGAUGAGGUGGGCCAGUCCCCAGCAGCAGUGGGGCUGGG
GGCAGGGGAGCAGGGGGGCACGUAGGCAUCCCCCAUGCCAGGCCUGAGCCUUGCUGUCUCUACCACCCCAGCCAGUG
GCCGAGGAGCCCUUCACCUUCGCCAUGGAGCUGGAUGACCUACCUAAGGAGCGGCUGAAGGAGCUCAUCUUCCAGGA
GACAGCACGCUUCCAGCCCGGAGUGCUGGAGGCCCCCUAGCCCAGACAGACAUCUCUGCACCCUGGGGCCUGGACCU
GCCUCCUGCCUGCCCCUCUCCCGCCAGACUGUUAGAAAAUGGACACUGUGCCCAGCCCGGACCUUGGCAGCCCAGGCC
GGGGUGGAGCAUGGGCCUGGCCACCUCUCUCCUUUGCUGAGGCCUCCAGCUUCAGGCAGGCCAAGGCCUUCUCCUCC
CCACCCGCCCUCCCCACGGGGCCUCGGGACCUCAGGUGGCCCCAGUUCAAUCUCCCGCUGCUGCUGCUGCGCCCUUAC
CUUCCCCAGCGUCCCAGUCUCUGGCAGUUCUGGAAUGGAAGGGUUCUGGCUGCCCCAACCUGCUGAAGGGCAGAGGU
GGAGGGUGGGGGGCGCUGAGUAGGGACUCAGGGCCAUGCCUGCCCCCCUCAUCUCAUUCAAACCCCACCCUAGUUUC
CCUGAAGGAACAUUCCUUAGUCUCAAGGGCUAGCAUCCCUGAGGAGCCAGGCCGGGCCGAAUCCCCUCCCUGUCAAA
GCUGUCACUUCGCGUGCCCUCGCUGCUUCUGUGUGUGGUGAGCAGAAGUGGAGCUGGGGGGCGUGGAGAGCCCGGCG
CCCCUGCCACCUCCCUGACCCGUCUAAUAUAUAAAUAUAGAGAUGUGUCUAUGGCUGAAAAAAAAAAAAAAAAAAA
AAAAAAAA
<SEQ ID NO. 1159;RNA;Homo sapiens>
CUGGCGCGCGCGGCCCUGCGGGUGACAGGCAGGCGGGAAGGGGCGGGGCCUCGGGCGGGGCCGCCGUGGGG
AGGAGGGCGGUGGGAGGGGAGGAGUGGAGAUGGCGGCGGCGGCGGCUCAGGGGGGCGGGGGCGGGGAGCCCCGUAG
AA CCGAGGGGGUCGGCCCGGGGGUCCCGGGGGAGGUGGAGAUGGUGAAGGGGCAGCCGUUCGACGUGGGCCCGCGCU
ACACGCAGUUGCAGUACAUCGGCGAGGGCGCGUACGGCAUGGUCAGCUCGGCCUAUGACCACGUGCGCAAGACUCGC
GUGGCCAUCAAGAAGAUCAGCCCCUUCGAACAUCAGACCUACUGCCAGCGCACGCUCCGGGAGAUCCAGAUCCUGCU
GCGCUUCCGCCAUGAGAAUGUCAUCGGCAUCCGAGACAUUCUGCGGGCGUCCACCCUGGAAGCCAUGAGAGAUGUCU
ACAUUGUGCAGGACCUGAUGGAGACUGACCUGUACAAGUUGCUGAAAAGCCAGCAGCUGAGCAAUGACCAUAUCUGC
UACUUCCUCUACCAGAUCCUGCGGGGCCUCAAGUACAUCCACUCCGCCAACGUGCUCCACCGAGAUCUAAAGCCCUCC
AACCUGCUCAUCAACACCACCUGCGACCUUAAGAUUUGUGAUUUCGGCCUGGCCCGGAUUGCCGAUCCUGAGCAUGA
CCACACCGGCUUCCUGACGGAGUAUGUGGCUACGCGCUGGUACCGGGCCCCAGAGAUCAUGCUGAACUCCAAGGGCU
AUACCAAGUCCAUCGACAUCUGGUCUGUGGGCUGCAUUCUGGCUGAGAUGCUCUCUAACCGGCCCAUCUUCCCUGGC
AAGCACUACCUGGAUCAGCUCAACCACAUUCUGGGCAUCCUGGGCUCCCCAUCCCAGGAGGACCUGAAUUGUAUCAU
CAACAUGAAGGCCCGAAACUACCUACAGUCUCUGCCCUCCAAGACCAAGGUGGCUUGGGCCAAGCUUUUCCCCAAGU
CAGACUCCAAAGCCCUUGACCUGCUGGACCGGAUGUUAACCUUUAACCCCAAUAAACGGAUCACAGUGGAGGAAGCG
CUGGCUCACCCCUACCUGGAGCAGUACUAUGACCCGACGGAUGAGCCAGUGGCCGAGGAGCCCUUCACCUUCGCCAU
GGAGCUGGAUGACCUACCUAAGGAGCGGCUGAAGGAGCUCAUCUUCCAGGAGACAGCACGCUUCCAGCCCGGAGUGC
UGGAGGCCCCCUAGCCCAGACAGACAUCUCUGCACCCUGGGGCCUGGACCUGCCUCCUGCCUGCCCCUCUCCCGCCAG
ACUGUUAGAAAAUGGACACUGUGCCCAGCCCGGACCUUGGCAGCCCAGGCCGGGGUGGAGCAUGGGCCUGGCCACCU
CUCUCCUUUGCUGAGGCCUCCAGCUUCAGGCAGGCCAAGGCCUUCUCCUCCCCACCCGCCCUCCCCACGGGGCCUCGG
GACCUCAGGUGGCCCCAGUUCAAUCUCCCGCUGCUGCUGCUGCGCCCUUACCUUCCCCAGCGUCCCAGUCUCUGGCAG
UUCUGGAAUGGAAGGGUUCUGGCUGCCCCAACCUGCUGAAGGGCAGAGGUGGAGGGUGGGGGGCGCUGAGUAGGGA
CUCAGGGCCAUGCCUGCCCCCCUCAUCUCAUUCAAACCCCACCCUAGUUUCCCUGAAGGAACAUUCCUUAGUCUCAAG
GGCUAGCAUCCCUGAGGAGCCAGGCCGGGCCGAAUCCCCUCCCUGUCAAAGCUGUCACUUCGCGUGCCCUCGCUGCU
UCUGUGUGUGGUGAGCAGAAGUGGAGCUGGGGGGCGUGGAGAGCCCGGCGCCCCUGCCACCUCCCUGACCCGUCUAA
UAUAUAAAUAUAGAGAUGUGUCUAUGGCUGAAAAAAAAAAAAAAAAAAAAAAAAAAA
<SEQ ID NO. 1160;RNA;Homo sapiens>
CUGGCGCGCGCGGCCCUGCGGGUGACAGGCAGGCGGGAAGGGGCGGGGCCUCGGGCGGGGCCGCCGUGGGG
AGGAGGGCGGUGGGAGGGGAGGAGUGGAGAUGGCGGCGGCGGCGGCUCAGGGGGGCGGGGGCGGGGAGCCCCGUAG
AACCGAGGGGGUCGGCCCGGGGGUCCCGGGGGAGGUGGAGAUGGUGAAGGGGCAGCCGUUCGACGUGGGCCCGCGCU
ACACGCAGUUGCAGUACAUCGGCGAGGGCGCGUACGGCAUGGUCAGCUCGGCCUAUGACCACGUGCGCAAGACUCGC
GUGGCCAUCAAGAAGAUCAGCCCCUUCGAACAUCAGACCUACUGCCAGCGCACGCUCCGGGAGAUCCAGAUCCUGCU
GCGCUUCCGCCAUGAGAAUGUCAUCGGCAUCCGAGACAUUCUGCGGGCGUCCACCCUGGAAGCCAUGAGAGAUGUCU
ACAUUGUGCAGGACCUGAUGGAGACUGACCUGUACAAGUUGCUGAAAAGCCAGCAGCUGAGCAAUGACCAUAUCUGC
UACUUCCUCUACCAGAUCCUGCGGGGCCUCAAGUACAUCCACUCCGCCAACGUGCUCCACCGAGAUCUAAAGCCCUCC
AACCUGCUCAUCAACACCACCUGCGACCUUAAGAUUUGUGAUUUCGGCCUGGCCCGGAUUGCCGAUCCUGAGCAUGA
CCACACCGGCUUCCUGACGGAGUAUGUGGCUACGCGCUGGUACCGGGCCCCAGAGAUCAUGCUGAACUCCAAGGGCU
AUACCAAGUCCAUCGACAUCUGGUCUGUGGGCUGCAUUCUGGCUGAGAUGCUCUCUAACCGGCCCAUCUUCCCUGGC
AAGCACUACCUGGAUCAGCUCAACCACAUUCUGGCCCUUGACCUGCUGGACCGGAUGUUAACCUUUAACCCCAAUAA
ACGGAUCACAGUGGAGGAAGCGCUGGCUCACCCCUACCUGGAGCAGUACUAUGACCCGACGGAUGAGCCAGUGGCCG
AGGAGCCCUUCACCUUCGCCAUGGAGCUGGAUGACCUACCUAAGGAGCGGCUGAAGGAGCUCAUCUUCCAGGAGACA
GCACGCUUCCAGCCCGGAGUGCUGGAGGCCCCCUAGCCCAGACAGACAUCUCUGCACCCUGGGGCCUGGACCUGCCUC
CUGCCUGCCCCUCUCCCGCCAGACUGUUAGAAAAUGGACACUGUGCCCAGCCCGGACCUUGGCAGCCCAGGCCGGGG
UGGAGCAUGGGCCUGGCCACCUCUCUCCUUUGCUGAGGCCUCCAGCUUCAGGCAGGCCAAGGCCUUCUCCUCCCCACC
CGCCCUCCCCACGGGGCCUCGGGACCUCAGGUGGCCCCAGUUCAAUCUCCCGCUGCUGCUGCUGCGCCCUUACCUUCC
CCAGCGUCCCAGUCUCUGGCAGUUCUGGAAUGGAAGGGUUCUGGCUGCCCCAACCUGCUGAAGGGCAGAGGUGGAGG
GUGGGGGGCGCUGAGUAGGGACUCAGGGCCAUGCCUGCCCCCCUCAUCUCAUUCAAACCCCACCCUAGUUUCCCUGA
AGGAACAUUCCUUAGUCUCAAGGGCUAGCAUCCCUGAGGAGCCAGGCCGGGCCGAAUCCCCUCCCUGUCAAAGCUGU
CACUUCGCGUGCCCUCGCUGCUUCUGUGUGUGGUGAGCAGAAGUGGAGCUGGGGGGCGUGGAGAGCCCGGCGCCCCU
GCCACCUCCCUGACCCGUCUAAUAUAUAAAUAUAGAGAUGUGUCUAUGGCUGAAAAAAAAAAAAAAAAAAAAAAAA
AAA
<SEQ ID NO. 1161;RNA;Artificial Sequence> cuggcgcgcgcggcccugc
741-3787

CA 02677068 2009-09-01
<SEQ ID NO. I162;RNA;Artificial Sequence> cgggugacaggcaggcggg
<SEQ ID NO. 1163;RNA;Artificial Sequence> gaaggggcggggccucggg
<SEQ ID NO. 1164;RNA;Artificial Sequence> gcggggccgccguggggag
<SEQ ID NO. 1165;RNA;Artificial Sequence> ggagggcggugggagggga
<SEQ ID NO. 1166;RNA;Artificial Sequence> aggaguggagauggcggcg
<SEQ ID NO. 1167;RNA;Artificial Sequence> ggcggcggcucaggggggc
<SEQ ID NO. 1168;RNA;Artificial Sequence> cgggggcggggagccccgu
<SEQ ID NO. 1169;RNA;Artificial Sequence> uagaaccgagggggucggc
<SEQ ID NO. 1170;RNA;Artificial Sequence> cccgggggucccgggggag
<SEQ ID NO. 1171;RNA;Artificial Sequence> gguggagauggugaagggg
<SEQ ID NO. 1172;RNA;Artificial Sequence> gcagccguucgacgugggc
<SEQ ID NO. 1173;RNA;Artificial Sequence> cccgcgcuacacgcaguug
<SEQ ID NO. 1174;RNA;Artificial Sequence> gcaguacaucggcgagggc
<SEQ ID NO. 1175;RNA;Artificial Sequence> cgcguacggcauggucagc
<SEQ ID NO. 1176;RNA;Artificial Sequence> cucggccuaugaccacgug
<SEQ ID NO. 1177;RNA;Artificial Sequence> gcgcaagacucgcguggcc
<SEQ ID NO. 1178;RNA;Artificial Sequence> caucaagaagaucagcccc
<SEQ ID NO. 1179;RNA;Artificial Sequence> cuucgaacaucagaccuac
<SEQ ID NO. 1180;RNA;Artificial Sequence> cugccagcgcacgcuccgg
<SEQ ID NO. 1181;RNA;Artificial Sequence> ggagauccagauccugcug
<SEQ ID NO. 1182;RNA;Artificial Sequence> gcgcuuccgccaugagaau
<SEQ ID NO. 1183;RNA;Artificial Sequence> ugucaucggcauccgagac
<SEQ ID NO. 11 84;RNA;Artificial Sequence> cauucugcgggcguccacc
<SEQ ID NO. 1185;RNA;Artificial Sequence> ccuggaagccaugagagau
<SEQ ID NO. 1186;RNA;Artificial Sequence> ugucuacauugugcaggac
<SEQ ID NO. 1187;RNA;Artificial Sequence> ccugauggagacugaccug
<SEQ ID NO. 1188;RNA;Artificial Sequence> guacaaguugcugaaaagc
<SEQ ID NO. 1189;RNA;Artificial Sequence> ccagcagcugagcaaugac
<SEQ ID NO. 1190;RNA;Artificial Sequence> ccauaucugcuacuuccuc
<SEQ ID NO. 1191;RNA;Artificial Sequence> cuaccagauccugcggggc
<SEQ ID NO. 1192;RNA;Artificial Sequence> ccucaaguacauccacucc
<SEQ ID NO. 1193;RNA;Artificial Sequence> cgccaacgugcuccaccga
<SEQ ID NO. 1194;RNA;Artificial Sequence> agaucuaaagcccuccaac
<SEQ ID NO. 1195;RNA;Artificial Sequence> ccugcucaucaacaccacc
<SEQ ID NO. 1196;RNA;Artificial Sequence> cugcgaccuuaagauuugu
<SEQ ID NO. 1197;RNA;Artificial Sequence> ugauuucggccuggcccgg
<SEQ ID NO. 1198;RNA;Artificial Sequence> gauugccgauccugagcau
<SEQ ID NO. 1199;RNA;Artificial Sequence> ugaccacaccggcuuccug
<SEQ ID NO. 1200;RNA;Artificial Sequence> gacggaguauguggcuacg
<SEQ ID NO. 1201;RNA;Artificial Sequence> gcgcugguaccgggcccca
<SEQ ID NO. 1202;RNA;Artificial Sequence> agagaucaugcugaacucc
<SEQ ID NO. 1203;RNA;Artificial Sequence> caagggcuauaccaagucc
<SEQ ID NO. 1204;RNA;Artificial Sequence> caucgacaucuggucugug
<SEQ ID NO. 1205;RNA;Artificial Sequence> gggcugcauucuggcugag
<SEQ ID NO. 1206;RNA;Artificial Sequence> gaugcucucuaaccggccc
<SEQ ID NO. 1207;RNA;Artificial Sequence> caucuucccuggcaagcac
<SEQ ID NO. 1208;RNA;Artificial Sequence> cuaccuggaucagcucaac
<SEQ ID NO. 1209;RNA;Artificial Sequence> ccacauucugggcauccug
<SEQ ID NO. 1210;RNA;Artificial Sequence> gggcuccccaucccaggag
<SEQ ID NO. 1211;RNA;Artificial Sequence> ggaccugaauuguaucauc
<SEQ ID NO. 1212;RNA;Artificial Sequence> caacaugaaggcccgaaac
<SEQ ID NO. 1213;RNA;Artificial Sequence> cuaccuacagucucugccc
<SEQ ID NO. 1214;RNA;Artificial Sequence> cuccaagaccaagguggcu
<SEQ ID NO. 1215;RNA;Artificial Sequence> uugggccaagcuuuucccc
<SEQ ID NO. 1216;RNA;Artificial Sequence> caagucagacuccaaagcc
<SEQ ID NO. 1217;RNA;Artificial Sequence> ccuugaccugcuggaccgg
<SEQ ID NO. 1218;RNA;Artificial Sequence> gauguuaaccuuuaacccc
<SEQ ID NO. 1219;RNA;Artificial Sequence> caauaaacggaucacagug
<SEQ ID NO. 1220;RNA;Artificial Sequence> ggaggaagcgcuggcucac
<SEQ ID NO. 1221;RNA;Artificial Sequence> ccccuaccuggagcaguac
<SEQ ID NO. 1222;RNA;Artificial Sequence> cuaugacccgacggaugag
<SEQ ID NO. 1223;RNA;Artificial Sequence> gccaguggccgaggagccc
<SEQ ID NO. 1224;RNA;Artificial Sequence> cuucaccuucgccauggag
<SEQ ID NO. 1225;RNA;Artificial Sequence> gcuggaugaccuaccuaag
<SEQ ID NO. 1226;RNA;Artificial Sequence> ggagcggcugaaggagcuc
<SEQ ID NO. 1227;RNA;Artificial Sequence> caucuuccaggagacagca
<SEQ ID NO. 1228;RNA;Artificial Sequence> acgcuuccagcccggagug
<SEQ ID NO. 1229;RNA;Artificial Sequence> gcuggaggcccccuagccc
<SEQ ID NO. 1230;RNA;Artificial Sequence> cagacagacaucucugcac
<SEQ ID NO. 1231;RNA;Artificial Sequence> cccuggggccuggaccugc
<SEQ ID NO. 1232;RNA;Artificial Sequence> ccuccugccugccccucuc
<SEQ ID NO. 1233;RNA;Artificial Sequence> cccgccagacuguuagaaa
<SEQ ID NO. I234;RNA;Artificial Sequence> aauggacacugugcccagc
741-3788

CA 02677068 2009-09-01
<SEQ ID NO. 1235;RNA;Artificial Sequence> cccggaccuuggcagccca
<SEQ ID NO. 1236;RNA;Artificial Sequence> aggccgggguggagcaugg
<SEQ ID NO. 1237;RNA;Artificial Sequence> ggccuggccaccucucucc
<SEQ ID NO. 1238;RNA;Artificial Sequence> cuuugcugaggccuccagc
<SEQ ID NO. 1239;RNA;Artificial Sequence> cuucaggcaggccaaggcc
<SEQ ID NO. 1240;RNA;Artificial Sequence> cuucuccuccccacccgcc
<SEQ ID NO. 1241;RNA;Artificial Sequence> ccuccccacggggccucgg
<SEQ ID NO. 1242;RNA;Artificial Sequence> ggaccucagguggccccag
<SEQ ID NO. 1243;RNA;Artificial Sequence> guucaaucucccgcugcug
<SEQ ID NO. 1244;RNA;Artificial Sequence> gcugcugcgcccuuaccuu
<SEQ ID NO. 1245;RNA;Artificial Sequence> uccccagcgucccagucuc
<SEQ ID NO. 1246;RNA;Artificial Sequence> cuggcaguucuggaaugga
<SEQ ID NO. 1247;RNA;Artificial Sequence> aaggguucuggcugcccca
<SEQ ID NO. 1248;RNA;Artificial Sequence> aaccugcugaagggcagag
<SEQ ID NO. 1249;RNA;Artificial Sequence> gguggaggguggggggcgc
<SEQ ID NO. 1250;RNA;Artificial Sequence> cugaguagggacucagggc
<SEQ ID NO. 1251;RNA;Artificial Sequence> ccaugccugccccccucau
<SEQ ID NO. 1252;RNA;Artificial Sequence> ucucauucaaaccccaccc
<SEQ ID NO. 1253;RNA;Artificial Sequence> cuaguuucccugaaggaac
<SEQ ID NO. 1254;RNA;Artificial Sequence> cauuccuuagucucaaggg
<SEQ ID NO. 1255;RNA;Artificial Sequence> gcuagcaucccugaggagc
<SEQ ID NO. 1256;RNA;Artificial Sequence> ccaggccgggccgaauccc
<SEQ ID NO. 1257;RNA;Artificial Sequence> ccucccugucaaagcuguc
<SEQ ID NO. 1258;RNA;Artificial Sequence> cacuucgcgugcccucgcu
<SEQ ID NO. 1259;RNA;Artificial Sequence> ugcuucuguguguggugag
<SEQ ID NO. 1260;RNA;Artificial Sequence> gcagaaguggagcuggggg
<SEQ ID NO. 1261;RNA;Artificial Sequence> ggcguggagagcccggcgc
<SEQ ID NO. 1262;RNA;Artificial Sequence> ccccugccaccucccugac
<SEQ ID NO. 1263;RNA;Artificial Sequence> cccgucuaauauauaaaua
<SEQ ID NO. 1264;RNA;Artificial Sequence> auagagaugugucuauggc
<SEQ ID NO. 1265;RNA;Artificial Sequence> ccacauucuggcccuugac
<SEQ ID NO. 1266;RNA;Artificial Sequence> ccugcuggaccggauguua
<SEQ ID NO. 1267;RNA;Artificial Sequence> aaccuuuaaccccaauaaa
<SEQ ID NO. 1268;RNA;Artificial Sequence> acggaucacaguggaggaa
<SEQ ID NO. 1269;RNA;Artificial Sequence> agcgcuggcucaccccuac
<SEQ ID NO. 1270;RNA;Artificial Sequence> ccuggagcaguacuaugac
<SEQ ID NO. 1271;RNA;Artificial Sequence> cccgacggaugagccagug
<SEQ ID NO. 1272;RNA;Artificial Sequence> ggccgaggagcccuucacc
<SEQ ID NO. 1273;RNA;Artificial Sequence> cuucgccauggagcuggau
<SEQ ID NO. 1274;RNA;Artificial Sequence> ugaccuaccuaaggagcgg
<SEQ ID NO. 1275;RNA;Artificial Sequence> gcugaaggagcucaucuuc
<SEQ ID NO. 1276;RNA;Artificial Sequence> ccaggagacagcacgcuuc
<SEQ ID NO. 1277;RNA;Artificial Sequence> ccagcccggagugcuggag
<SEQ ID NO. 1278;RNA;Artificial Sequence> ggcccccuagcccagacag
<SEQ ID NO. 1279;RNA;Artificial Sequence> gacaucucugcacccuggg
<SEQ ID NO. 1280;RNA;Artificial Sequence> ggccuggaccugccuccug
<SEQ ID NO. 1281;RNA;Artificial Sequence> gccugccccucucccgcca
<SEQ ID NO. 1282;RNA;Artificial Sequence> agacuguuagaaaauggac
<SEQ ID NO. 1283;RNA;Artificial Sequence> cacugugcccagcccggac
<SEQ ID NO. 1284;RNA;Artificial Sequence> ccuuggcagcccaggccgg
<SEQ ID NO. 1285;RNA;Artificial Sequence> ggguggagcaugggccugg
<SEQ ID NO. 1286;RNA;Artificial Sequence> gccaccucucuccuuugcu
<SEQ ID NO. 1287;RNA;Artificial Sequence> ugaggccuccagcuucagg
<SEQ ID NO. 1288;RNA;Artificial Sequence> gcaggccaaggccuucucc
<SEQ ID NO. 1289;RNA;Artificial Sequence> cuccccacccgcccucccc
<SEQ ID NO. 1290;RNA;Artificial Sequence> cacggggccucgggaccuc
<SEQ ID NO. 1291;RNA;Artificial Sequence> cagguggccccaguucaau
<SEQ ID NO. 1292;RNA;Artificial Sequence> ucucccgcugcugcugcug
<SEQ ID NO. 1293;RNA;Artificial Sequence> gcgcccuuaccuuccccag
<SEQ ID NO. 1294;RNA;Artificial Sequence> gcgucccagucucuggcag
<SEQ ID NO. 1295;RNA;Artificial Sequence> guucuggaauggaaggguu
<SEQ ID NO. 1296;RNA;Artificial Sequence> ucuggcugccccaaccugc
<SEQ ID NO. 1297;RNA;Artificial Sequence> cugaagggcagagguggag
<SEQ ID NO. 1298;RNA;Artificial Sequence> ggguggggggcgcugagua
<SEQ ID NO. 1299;RNA;Artificial Sequence> agggacucagggccaugec
<SEQ ID NO. 1300;RNA;Artificial Sequence> cugccccccucaucucauu
<SEQ ID NO. 1301;RNA;Artificial Sequence> ucaaaccccacccuaguuu
<SEQ ID NO. 1302;RNA;Artificial Sequence> ucccugaaggaacauuccu
<SEQ ID NO. 1303;RNA;Artificial Sequence> uuagucucaagggcuagca
<SEQ ID NO. 1304;RNA;Artificial Sequence> aucccugaggagccaggcc
<SEQ ID NO. 1305;RNA;Artificial Sequence> cgggccgaauccccucccu
<SEQ ID NO. 1306;RNA;Artificial Sequence> ugucaaagcugucacuucg
<SEQ ID NO. 1307;RNA;Artificial Sequence> gcgugcccucgcugcuucu
741-3789

CA 02677068 2009-09-01
<SEQ ID NO. 1308;RNA;Artificial Sequence> uguguguggugagcagaag
<SEQ ID NO. I309;RNA;Artificial Sequence> guggagcuggggggegugg
<SEQ ID NO. 1310;RNA;Artificial Sequence> gagagcccggcgccccugc
<SEQ ID NO. 1311;RNA;Artificial Sequence> ccaccucccugacccgucu
<SEQ ID NO. 1312;RNA;Artificial Sequence> uaauauauaaauauagaga
<SEQ ID NO. 1313;RNA;Artificial Sequence> augugucuauggcugaaaa
<SEQ ID NO. 1314;RNA;Artificial Sequence> ggugggccaguccccagca
<SEQ ID NO. 1315;RNA;Artificial Sequence> agcaguggggcugggggca
<SEQ ID NO. 1316;RNA;Artificial Sequence> aggggagcaggggggcacg
<SEQ ID NO. 1317;RNA;Artificial Sequence> guaggcaucccccaugcca
<SEQ ID NO. 1318;RNA;Artificial Sequence> aggccugagccuugcuguc
<SEQ ID NO. 1319;RNA;Artificial Sequence> cucuaccaccccagccagu
<SEQ ID NO. 1320;RNA;Artificial Sequence> uggccgaggagcccuucac
<SEQ ID NO. 1321;RNA;Artificial Sequence> ccuucgccauggagcugga
<SEQ ID NO. 1322;RNA;Artificial Sequence> augaccuaccuaaggagcg
<SEQ ID NO. 1323;RNA;Artificial Sequence> ggcugaaggagcucaucuu
<SEQ ID NO. 1324;RNA;Artificial Sequence> uccaggagacagcacgcuu
<SEQ ID NO. 1325;RNA;Artificial Sequence> uccagcccggagugcugga
<SEQ ID NO. 1326;RNA;Artificial Sequence> aggcccccuagcccagaca
<SEQ ID NO. 1327;RNA;Artificial Sequence> agacaucucugcacccugg
<SEQ ID NO. 1328;RNA;Artificial Sequence> gggccuggaccugccuccu
<SEQ ID NO. 1329;RNA;Artificial Sequence> ugccugccccucucccgcc
<SEQ ID NO. 1330;RNA;Artificial Sequence> cagacuguuagaaaaugga
<SEQ ID NO. 1331;RNA;Artificial Sequence> acacugugcccagcccgga
<SEQ ID NO. 1332;RNA;Artificial Sequence> accuuggcagcccaggccg
<SEQ ID NO. 1333;RNA;Artificial Sequence> gggguggagcaugggccug
<SEQ ID NO. 1334;RNA;Artificial Sequence> ggccaccucucuccuuugc
<SEQ ID NO. 1335;RNA;Artificial Sequence> cugaggccuccagcuucag
<SEQ ID NO. 1336;RNA;Artificial Sequence> ggcaggccaaggccuucuc
<SEQ ID NO. 1337;RNA;Artificial Sequence> ccuccccacccgcccuccc
<SEQ ID NO. 1338;RNA;Artificial Sequence> ccacggggccucgggaccu
<SEQ ID NO. 1339;RNA;Artificial Sequence> ucagguggccccaguucaa
<SEQ ID NO. 1340;RNA;Artificial Sequence> aucucccgcugcugcugcu
<SEQ ID NO. 1341;RNA;Artificial Sequence> ugcgcccuuaccuucccca
<SEQ ID NO. 1342;RNA;Artificial Sequence> agcgucccagucucuggca
<SEQ ID NO. 1343;RNA;Artificial Sequence> aguucuggaauggaagggu
<SEQ ID NO. 1344;RNA;Artificial Sequence> uucuggcugccccaaccug
<SEQ ID NO. 1345;RNA;Artificial Sequence> gcugaagggcagaggugga
<SEQ ID NO. 1346;RNA;Artificial Sequence> aggguggggggcgcugagu
<SEQ ID NO. 1347;RNA;Artificial Sequence> uagggacucagggccaugc
<SEQ ID NO. 1348;RNA;Artificial Sequence> ccugccccccucaucucau
<SEQ ID NO. 1349;RNA;Artificial Sequence> uucaaaccccacccuaguu
<SEQ ID NO. 1350;RNA;Artificial Sequence> uucccugaaggaacauucc
<SEQ ID NO. 1351;RNA;Artificial Sequence> cuuagucucaagggcuagc
<SEQ ID NO. 1352;RNA;Artificial Sequence> caucccugaggagccaggc
<SEQ ID NO. 1353;RNA;Artificial Sequence> ccgggccgaauccccuccc
<SEQ ID NO. I354;RNA;Artificial Sequence> cugucaaagcugucacuuc
<SEQ ID NO. 1355;RNA;Artificial Sequence> cgcgugcccucgcugcuuc
<SEQ ID NO. 1356;RNA;Artificial Sequence> cuguguguggugagcagaa
<SEQ ID NO. 1357;RNA;Artificial Sequence> aguggagcuggggggcgug
<SEQ ID NO. 1358;RNA;Artificial Sequence> ggagagcccggcgccccug
<SEQ ID NO. 1359;RNA;Artificial Sequence> gccaccucccugacceguc
<SEQ ID NO. 1360;RNA;Artificial Sequence> cuaauauauaaauauagag
<SEQ ID NO. 1361;RNA;Artificial Sequence> gaugugucuauggcugaaa
<SEQ ID NO. 1362;RNA;Artificial Sequence> cuggcgcgcgcggcccugcggguga
<SEQ ID NO. 1363;RNA;Artificial Sequence> acaggcaggcgggaaggggcggggc
<SEQ ID NO. 1364;RNA;Artificial Sequence> ccucgggcggggcegccguggggag
<SEQ ID NO. 1365;RNA;Artificial Sequence> ggagggcggugggaggggaggagug
<SEQ ID NO. 1366;RNA;Artificial Sequence> ggagauggcggcggcggcggcucag
<SEQ ID NO. 1367;RNA;Artificial Sequence> ggggggcgggggcggggagccccgu
<SEQ ID NO. 1368;RNA;Artificial Sequence> uagaaccgagggggucggcccgggg
<SEQ ID NO. 1369;RNA;Artificial Sequence> ggucccgggggagguggagauggug
<SEQ ID NO. 1370;RNA;Artificial Sequence> gaaggggcagccguucgacgugggc
<SEQ ID NO. 1371;RNA;Artificial Sequence> cccgcgcuacacgcaguugcaguac
<SEQ ID NO. 1372;RNA;Artificial Sequence> caucggcgagggcgcguacggcaug
<SEQ ID NO. 1373;RNA;Artificial Sequence> ggucagcucggccuaugaccacgug
<SEQ ID NO. 1374;RNA;Artificial Sequence> gcgcaagacucgcguggccaucaag
<SEQ ID NO. 1375;RNA;Artificial Sequence> gaagaucagccccuucgaacaucag
<SEQ ID NO. I376;RNA;Artificial Sequence> gaccuacugccagcgcacgcuccgg
<SEQ ID NO. 1377;RNA;Artificial Sequence> ggagauccagauccugcugcgcuuc
<SEQ ID NO. 1378;RNA;Artificial Sequence> ccgccaugagaaugucaucggcauc
<SEQ ID NO. I379;RNA;Artificial Sequence> ccgagacauucugcgggcguccacc
<SEQ ID NO. 1380;RNA;Artificial Sequence> ccuggaagccaugagagaugucuac
741-3790

CA 02677068 2009-09-01
<SEQ ID NO. 1381;RNA;Artificial Sequence> cauugugcaggaccugauggagacu
<SEQ ID NO. 1382;RNA;Artificial Sequence> ugaccuguacaaguugcugaaaagc
<SEQ ID NO. 1383;RNA;Artificial Sequence> ccagcagcugagcaaugaccauauc
<SEQ ID NO. I384;RNA;Artificial Sequence> cugcuacuuccucuaccagauccug
<SEQ ID NO. 1385;RNA;Artificial Sequence> gcggggccucaaguacauccacucc
<SEQ ID NO. 1386;RNA;Artificial Sequence> cgccaacgugcuccaccgagaucua
<SEQ ID NO. 1387;RNA;Artificial Sequence> aaagcccuccaaccugcucaucaac
<SEQ ID NO. 1388;RNA;Artificial Sequence> caccaccugcgaccuuaagauuugu
<SEQ ID NO. 1389;RNA;Artificial Sequence> ugauuucggccuggcccggauugcc
<SEQ ID NO. I390;RNA;Artificial Sequence> cgauccugagcaugaccacaccggc
<SEQ ID NO. 1391;RNA;Artificial Sequence> cuuccugacggaguauguggcuacg
<SEQ ID NO. 1392;RNA;Artificial Sequence> gcgcugguaccgggccccagagauc
<SEQ ID NO. 1393;RNA;Artificial Sequence> caugcugaacuccaagggcuauacc
<SEQ ID NO. 1394;RNA;Artificial Sequence> caaguccaucgacaucuggucugug
<SEQ ID NO. 1395;RNA;Artificial Sequence> gggcugcauucuggcugagaugcuc
<SEQ ID NO. 1396;RNA;Artificial Sequence> cucuaaccggcccaucuucccuggc
<SEQ ID NO. 1397;RNA;Artificial Sequence> caagcacuaccuggaucagcucaac
<SEQ ID NO. 1398;RNA;Artificial Sequence> ccacauucugggcauccugggcucc
<SEQ ID NO. 1399;RNA;Artificial Sequence> cccaucccaggaggaccugaauugu
<SEQ ID NO. 1400;RNA;Artificial Sequence> uaucaucaacaugaaggcccgaaac
<SEQ ID NO. 1401;RNA;Artificial Sequence> cuaccuacagucucugcccuccaag
<SEQ ID NO. 1402;RNA;Artificial Sequence> gaccaagguggcuugggccaagcuu
<SEQ ID NO. 1403;RNA;Artificial Sequence> uuuccccaagucagacuccaaagcc
<SEQ ID NO. 1404;RNA;Artificial Sequence> ccuugaccugcuggaccggauguua
<SEQ ID NO. 1405;RNA;Artificial Sequence> aaccuuuaaccccaauaaacggauc
<SEQ ID NO. 1406;RNA;Artificial Sequence> cacaguggaggaagcgcuggcucac
<SEQ ID NO. 1407;RNA;Artificial Sequence> ccccuaccuggagcaguacuaugac
<SEQ ID NO. 1408;RNA;Artificial Sequence> cccgacggaugagccaguggccgag
<SEQ ID NO. 1409;RNA;Artificial Sequence> ggagcccuucaccuucgccauggag
<SEQ ID NO. 1410;RNA;Artificial Sequence> gcuggaugaccuaccuaaggagcgg
<SEQ ID NO. 1411;RNA;Artificial Sequence> gcugaaggagcucaucuuccaggag
<SEQ ID NO. 1412;RNA;Artificial Sequence> gacagcacgcuuccagcccggagug
<SEQ ID NO. 1413;RNA;Artificial Sequence> gcuggaggcccccuagcccagacag
<SEQ ID NO. 1414;RNA;Artificial Sequence> gacaucucugcacccuggggccugg
<SEQ ID NO. 1415;RNA;Artificial Sequence> gaccugccuccugccugccccucuc
<SEQ ID NO. 1416;RNA;Artificial Sequence> cccgccagacuguuagaaaauggac
<SEQ ID NO. 1417;RNA;Artificial Sequence> cacugugcccagcccggaccuuggc
<SEQ ID NO. 1418;RNA;Artificial Sequence> cagcccaggccgggguggagcaugg
<SEQ ID NO. 1419;RNA;Artificial Sequence> ggccuggccaccucucuccuuugcu
<SEQ ID NO. 1420;RNA;Artificial Sequence> ugaggccuccagcuucaggcaggcc
<SEQ ID NO. 1421;RNA;Artificial Sequence> caaggccuucuccuccccacccgcc
<SEQ ID NO. 1422;RNA;Artificial Sequence> ccuccccacggggccucgggaccuc
<SEQ ID NO. 1423;RNA;Artificial Sequence> cagguggccccaguucaaucucccg
<SEQ ID NO. 1424;RNA;Artificial Sequence> gcugcugcugcugcgcccuuaccuu
<SEQ ID NO. 1425;RNA;Artificial Sequence> uccccagcgucccagucucuggcag
<SEQ ID NO. 1426;RNA;Artificial Sequence> guucuggaauggaaggguucuggcu
<SEQ ID NO. 1427;RNA;Artificial Sequence> ugccccaaccugcugaagggcagag
<SEQ ID NO. 1428;RNA;Artificial Sequence> gguggaggguggggggcgcugagua
<SEQ ID NO. 1429;RNA;Artificial Sequence> agggacucagggccaugccugcccc
<SEQ ID NO. 1430;RNA;Artificial Sequence> cccucaucucauucaaaccccaccc
<SEQ ID NO. 1431;RNA;Artificial Sequence> cuaguuucccugaaggaacauuccu
<SEQ ID NO. 1432;RNA;Artificial Sequence> uuagucucaagggcuagcaucccug
<SEQ ID NO. 1433;RNA;Artificial Sequence> gaggagccaggccgggccgaauccc
<SEQ ID NO. 1434;RNA;Artificial Sequence> ccucccugucaaagcugucacuucg
<SEQ ID NO. 1435;RNA;Artificial Sequence> gcgugcccucgcugcuucugugugu
<SEQ ID NO. 1436;RNA;Artificial Sequence> uggugagcagaaguggagcuggggg
<SEQ ID NO. 1437;RNA;Artificial Sequence> ggcguggagagcccggcgccccugc
<SEQ ID NO. 1438;RNA;Artificial Sequence> ccaccucccugacccgucuaauaua
<SEQ ID NO. 1439;RNA;Artificial Sequence> auaaauauagagaugugucuauggc
<SEQ ID NO. 1440;RNA;Artificial Sequence> ccacauucuggcccuugaccugcug
<SEQ ID NO. 1441;RNA;Artificial Sequence> ggaccggauguuaaccuuuaacccc
<SEQ ID NO. 1442;RNA;Artificial Sequence> caauaaacggaucacaguggaggaa
<SEQ ID NO. 1443;RNA;Artificial Sequence> agcgcuggcucaccccuaccuggag
<SEQ ID NO. 1444;RNA;Artificial Sequence> gcaguacuaugacccgacggaugag
<SEQ ID NO. 1445;RNA;Artificial Sequence> gccaguggccgaggagcccuucacc
<SEQ ID NO. 1446;RNA;Artificial Sequence> cuucgccauggagcuggaugaccua
<SEQ ID NO. 1447;RNA;Artificial Sequence> accuaaggagcggcugaaggagcuc
<SEQ ID NO. 1448;RNA;Artificial Sequence> caucuuccaggagacagcacgcuuc
<SEQ ID NO. 1449;RNA;Artificial Sequence> ccagcccggagugcuggaggccccc
<SEQ ID NO. 1450;RNA;Artificial Sequence> cuagcccagacagacaucucugcac
<SEQ ID NO. 1451;RNA;Artificial Sequence> cccuggggccuggaccugccuccug
<SEQ ID NO. 1452;RNA;Artificial Sequence> gccugccccucucccgccagacugu
<SEQ ID NO. 1453;RNA;Artificial Sequence> uuagaaaauggacacugugcccagc
741-3791

CA 02677068 2009-09-01
<SEQ ID NO. 1454;RNA;Artificial Sequence> cccggaccuuggcagcccaggccgg
<SEQ ID NO. 1455;RNA;Artificial Sequence> ggguggagcaugggccuggccaccu
<SEQ ID NO. 1456;RNA;Artificial Sequence> ucucuccuuugcugaggccuccagc
<SEQ ID NO. 1457;RNA;Artificial Sequence> cuucaggcaggccaaggccuucucc
<SEQ ID NO. 1458;RNA;Artificial Sequence> cuccccacccgcccuccccacgggg
<SEQ ID NO. 1459;RNA;Artificial Sequence> gccucgggaccucagguggccccag
<SEQ ID NO. 1460;RNA;Artificial Sequence> guucaaucucccgcugcugcugcug
<SEQ ID NO. 1461;RNA;Artificial Sequence> gcgcccuuaccuuccccagcguccc
<SEQ ID NO. 1462;RNA;Artificial Sequence> cagucucuggcaguucuggaaugga
<SEQ ID NO. 1463;RNA;Artificial Sequence> aaggguucuggcugccccaaccugc
<SEQ ID NO. 1464;RNA;Artificial Sequence> cugaagggcagagguggaggguggg
<SEQ ID NO. 1465;RNA;Artificial Sequence> ggggcgcugaguagggacucagggc
<SEQ ID NO. 1466;RNA;Artificial Sequence> ccaugccugccccccucaucucauu
<SEQ ID NO. 1467;RNA;Artificial Sequence> ucaaaccccacccuaguuucccuga
<SEQ ID NO. 1468;RNA;Artificial Sequence> aaggaacauuccuuagucucaaggg
<SEQ ID NO. 1469;RNA;Artificial Sequence> gcuagcaucccugaggagccaggcc
<SEQ ID NO. 1470;RNA;Artificial Sequence> cgggccgaauccccucccugucaaa
<SEQ ID NO. 1471;RNA;Artificial Sequence> agcugucacuucgcgugcccucgcu
<SEQ ID NO. 1472;RNA;Artificial Sequence> ugcuucuguguguggugagcagaag
<SEQ ID NO. 1473;RNA;Artificial Sequence> guggagcuggggggcguggagagcc
<SEQ ID NO. 1474;RNA;Artificial Sequence> ccggcgccccugccaccucccugac
<SEQ ID NO. 1475;RNA;Artificial Sequence> cccgucuaauauauaaauauagaga
<SEQ ID NO. 1476;RNA;Artificial Sequence> cccgacggaugaggugggccagucc
<SEQ ID NO. 1477;RNA;Artificial Sequence> cccagcagcaguggggcugggggca
<SEQ ID NO. 1478;RNA;Artificial Sequence> aggggagcaggggggcacguaggca
<SEQ ID NO. 1479;RNA;Artificial Sequence> aucccccaugccaggccugagccuu
<SEQ ID NO. 1480;RNA;Artificial Sequence> ugcugucucuaccaccccagccagu
<SEQ ID NO. 1481;RNA;Artificial Sequence> uggccgaggagcccuucaccuucgc
<SEQ ID NO. 1482;RNA;Artificial Sequence> ccauggagcuggaugaccuaccuaa
<SEQ ID NO. 1483;RNA;Artificial Sequence> aggagcggcugaaggagcucaucuu
<SEQ ID NO. 1484;RNA;Artificial Sequence> uccaggagacagcacgcuuccagcc
<SEQ ID NO. 1485;RNA;Artificial Sequence> ccggagugcuggaggcccccuagcc
<SEQ ID NO. 1486;RNA;Artificial Sequence> ccagacagacaucucugcacccugg
<SEQ ID NO. 1487;RNA;Artificial Sequence> gggccuggaccugccuccugccugc
<SEQ ID NO. 1488;RNA;Artificial Sequence> ccccucucccgccagacuguuagaa
<SEQ ID NO. 1489;RNA;Artificial Sequence> aaauggacacugugcccagcccgga
<SEQ ID NO. 1490;RNA;Artificial Sequence> accuuggcagcccaggccggggugg
<SEQ ID NO. 1491;RNA;Artificial Sequence> gagcaugggccuggccaccucucuc
<SEQ ID NO. 1492;RNA;Artificial Sequence> ccuuugcugaggccuccagcuucag
<SEQ ID NO. 1493;RNA;Artificial Sequence> ggcaggccaaggccuucuccucccc
<SEQ ID NO. 1494;RNA;Artificial Sequence> cacccgcccuccccacggggccucg
<SEQ ID NO. 1495;RNA;Artificial Sequence> gggaccucagguggccccaguucaa
<SEQ ID NO. 1496;RNA;Artificial Sequence> aucucccgcugcugcugcugcgccc
<SEQ ID NO. 1497;RNA;Artificial Sequence> cuuaccuuccccagcgucccagucu
<SEQ ID NO. 1498;RNA;Artificial Sequence> ucuggcaguucuggaauggaagggu
<SEQ ID NO. 1499;RNA;Artificial Sequence> uucuggcugccccaaccugcugaag
<SEQ ID NO. 1500;RNA;Artificial Sequence> gggcagagguggaggguggggggcg
<SEQ ID NO. 1501;RNA;Artificial Sequence> gcugaguagggacucagggccaugc
<SEQ ID NO. 1502;RNA;Artificial Sequence> ccugccccccucaucucauucaaac
<SEQ ID NO. 1503;RNA;Artificial Sequence> ccccacccuaguuucccugaaggaa
<SEQ ID NO. 1504;RNA;Artificial Sequence> acauuccuuagucucaagggcuagc
<SEQ ID NO. 1505;RNA;Artificial Sequence> caucccugaggagccaggccgggcc
<SEQ ID NO. 1506;RNA;Artificial Sequence> cgaauccccucccugucaaagcugu
<SEQ ID NO. 1507;RNA;Artificial Sequence> ucacuucgcgugcccucgcugcuuc
<SEQ ID NO. 1508;RNA;Artificial Sequence> cuguguguggugagcagaaguggag
<SEQ ID NO. 1509;RNA;Artificial Sequence> gcuggggggcguggagagcccggcg
<SEQ ID NO. 1510;RNA;Artificial Sequence> gccccugccaccucccugacccguc
<SEQ ID NO. 1511;RNA;Artificial Sequence> cuaauauauaaauauagagaugugu
741-3792

CA 02677068 2009-09-01
DEMANDES OU BREVETS VOLUMINEUX
LA PRESENTE PARTIE DE CETTE DEMANDE OU CE BREVETS
COMPREND PLUS D'UN TOME.
CECI EST LE TOME 16 DE 16
NOTE: Pour les tomes additionels, veillez contacter le Bureau Canadien des
Brevets.
JUMBO APPLICATIONS / PATENTS
THIS SECTION OF THE APPLICATION / PATENT CONTAINS MORE
THAN ONE VOLUME.
THIS IS VOLUME _16 OF 16
NOTE: For additional volumes please contact the Canadian Patent Office.

Dessin représentatif